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Query: [U] KOG0090 Signal recognition particle receptor, beta subunit (small G protein superfamily), from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDNLEDLKIVAEQWSKQGLEFVQKIPPPQLYTAIGVLLLATIWLLSIRLFRRTKSNTVLLSGLSGSGKTVLFYQLRDGSSHQGAVTSMEPNEGTFVLHNENNTKKGKVKPVHLIDVPGHSRLISKLEEYLPRAAAVVFVVDALEFLPNIRAASEYLYDILTNASVIKNKTPVLLCCNKTDKVTAHTKEFIRKQMEKEIDKLRVSRSAISTADIANDFTLGIEGEVFSFSHCHNKVTVAEASGLTGETDQVQEFIREHVKPLast
1 -97.100[U] KOG0090 Signal recognition particle receptor, beta subunit (small G protein superfamily)  ali  100  1MDNLEDLKIVAEQWSKQGLEFVQKIPPPQLYTAIGVLLLATIWLLSIRLFRRTKSNTVLLSGLSGSGKTVLFYQLRDGSSHQGAVTSMEPNEGTFVLHNENNTKKGKVKPVHLIDVPGHSRLISKLEEYLPRAAAVVFVVDALEFLPNIRAASEYLYDILTNASVIKNKTPVLLCCNKTDKVTAHTKEFIRKQMEKEIDKLRVSRSAISTADIANDFTLGIEGEVFSFSHCHNKVTVAEASGLTGETDQVQEFIREHVKP 260
2 -53.200[U] KOG0070 GTP-binding ADP-ribosylation factor Arf1  ali follow..  18  1......................................MGLSFGKLFSRLFAKKEMRILMVGLDAAGKTTILYKLKLGEIV-TTIPTIGFNVETV---------EYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDR-VVEARDELHRMLNEDEL--RDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRHWYIQSTCATSGEGLYEGLDWLSNNIAS.............................. 179
3 -53.200[R] KOG0074 GTP-binding ADP-ribosylation factor-like protein ARL3  ali follow..  17  1......................................MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASED-ISHITPTQGFNIKSV---------QSQGFKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKR-FEETGQELAELLEEEKL--SCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNA.............................. 179
4 -53.000[U] KOG0071 GTP-binding ADP-ribosylation factor Arf6 (dArf3)  ali follow..  20  4.....................................SLFKGFSKPFSRLFSNKEMRILMLGLDAAGKTTILYKLKLNQSV-VTIPTVGFNVETV---------TYKNIKFNVWDVGGQDKIRPLWRHYFTGTKGLIFVVDSADSNR-ISEARQELHRIISDREM--RDCLLLVLANKQDLPGALSPAQITDVLQLDKLKDRLWNVQPTCALTGDGLLEGLAWLSQNAKL.............................. 183
5 -52.900[R] KOG0075 GTP-binding ADP-ribosylation factor-like protein  ali follow..  19  1...................................MLALINRILEWFKSIFWKEEMELTLVGLQFSGKTTFVNVIASGQFAEDMIPTVGFNMRKI---------TRGNVTIKVWDIGGQPRFRSMWERYCRGVNAIVYMVDAADLDK-LEASRNELHSLLDKPQL--AGIPVLVLGNKRDLPGALDETGLIERMNLSSIQDREICCYSISCKEKDNIDITLQWLIQHSKS.............................. 183
6 -52.800[U] KOG0072 GTP-binding ADP-ribosylation factor-like protein ARL1  ali follow..  17  1......................................MDGGVLSYFRGLLGSREMRILILGLDGAGKTTILYRLQVGEVV-TTIPTIGFNVEQV---------TYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSADRDR-IGISKDELLYMLREEEL--AGAILVVLANKQDMDGCMTVAEVHHALGLENLKNRTFQIFKTSATKGEGLDQAMDWLSNTLQS.............................. 179
7 -52.400[UZ] KOG0073 GTP-binding ADP-ribosylation factor-like protein ARL2  ali follow..  17  3.........................................LLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGED-IDTISPTLGFNIKTL---------EHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQR-MQDCQRELQSLLVEERL--AGATLLIFANKQDLPGALSSNAIREALELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSRIFTAD........................ 184
8 -51.900[R] COG1100 GTPase SAR1 and related small G proteins  ali follow..  22  1.....................................MGNIFSSMFDKLWGSNKELRILILGLDGAGKTTILYRLQIGEVV-TTKPTIGFNVETL---------SYKNLKLNVWDLGGQTSIRPYWRCYYADTAAVIFVVDSTDKDR-MSTASKELHLMLQEEEL--QDAALLVFANKQDQPGALSASEVSKELNLVELKDRSWSIVASSAIKGEGITEGLDWLIDVIKE.............................. 180
9 -51.500[U] KOG0076 GTP-binding ADP-ribosylation factor-like protein yARL3  ali follow..  18  1......................................MFHLVKGLYNNWNKKEQYSILILGLDNAGKTTFLETLKKEKALEKIQPTVGQNVATIPVDSK--------QILKFWDVGGQESLRSMWSEYYSLCHGIIFIVDSSDRER-LDECSTTLQSVVMDEEI--EGVPILMLANKQDRQDRMEVQDIKEVFNKIAEHIRDSRVLPISALTGEGVKDAIEWMIVRLER.............................. 188
10 -50.800[U] KOG0077 Vesicle coat complex COPII, GTPase subunit SAR1  ali follow..  17  1...................................MFLFDWFYGILASLGLWQKEAKILFLGLDNAGKTTLLHMLKDER-LVQHQPTQHPTSEELSI---------GKIKFKAFDLGGHQIARRVWKDYYAKVDAVVYLVDAYDKER-FAESKRELDALLSDEAL--ATVPFLILGNKIDIPYAASEDELRYHLGLTNFTTGKGKVTLGDSGV-------------------RPLEVFMCSIVRKGYGEGFKWLSQYIN. 193
11 -29.500[U] KOG3887 Predicted small GTPase involved in nuclear protein import  ali follow..  13  58..................................................STEVKPRILLMGLRRSGKSSIQKVVFHKMSPNETLSTNKICREDVSNSS--------FVNFQIWDFPGQIDFFDPTEMIFRGTGALIFVIDSQDDYM---EALARLHLTVTRAYKVNTDINFEVFIHKVDGLSDDHKIETQRDIHQRANDDLADAGLE-----------------------KIHLSFYLTSIYDHSIFEAFSKVVQKLIP 239
12 -28.700[R] COG2229 Predicted GTPase  ali follow..  18  2.....................................................RENKIIFTGPVGVGKTTAIAAISDEALVQTRNTTVAMDYGAISLD--------EDTKVHLYGTPGQERFNFMWEILSQGSMGLVLLLDNAR-----TNPLKDLEFFLHSFRGLLEKAPVVVGITKMDIRSQPGIDVYHKYLAKHNLNVPVFEIDARKEDDVKQLVSAM------LFSIDPGLEV....................... 178
13 -27.300[T] KOG3886 GTP-binding protein  ali follow..  12  36..................................................NTAMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRATILDRIHSLQINEHSHVRFLGNLVLNLWDCGGQDTFMENYDNIFRNVEVLIYVFDVES--RELEKDMHYYQSCLEAILQNSPDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSR----------------------------PLECSCFRTSIWDETLYKAWSSIVYQLIP 243
14 -25.900[U] KOG0096 GTPase Ran/TC4/GSP1 (nuclear protein transport pathway), small G protein superfamily  ali follow..  14  14........................................................KLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFY-----TNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTS-----RITYKNVPNWHRDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKK------------------------------------NLQYYDISAKSNNFEKPFLWLARKL.. 170
15 -24.700[R] KOG0091 GTPase Rab39, small G protein superfamily  ali follow..  16  11........................................................RLILIGDSTVGKSSLLKFFTDGKFAELSDPTVGVDFFARLI----EMKDGTQIKLQLWDTAGQERFRSITKSYYRNSVGVLLVYDISN-HASFEHIPLWMMEA--QRHIEPHRPVFALVGCKLDLINAGGHREVTTEEAQKFAKQHGLHFVETSARSGANV........................................... 164
16 -24.400[R] KOG0394 Ras-related GTPase  ali follow..  18  10........................................................KVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEV-----QFEDRLFTLQIWDTAGQERFQSLGVAFYRGADCCVLVYDVNS-MKSFENLNNWREEFLIQASPSDENFPFVLIGNKVDVDDGNSRVVSEKKAK-------------------------------AWCASKGNIPYFETSAKVGNVEEAFQCIAKDA.. 176
17 -24.100[R] KOG0395 Ras-related GTPase  ali follow..  14  21........................................................RMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIE------DFHRKVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVLVFSLDNRESFDEVKRLQKQILEVLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEA---------------------------------LLVSGDENCAYFEVSAKKNNVDEMFYVLFSMAK. 191
18 -23.900[R] KOG0079 GTP-binding protein H-ray, small G protein superfamily  ali follow..  14  12........................................................KLLIIGDSGVGKSSLLLRFADNTFSENYITTIGVDFKIRTM-----DINGQRVKLQIWDTAGQERFRTITSTYYRGTHGVVVVYDVTN-----GESFGNVKRWLQEIENNCDSVQKVLVGNKCEENERRVVLESDARNYAQSMNISFFETSAKEDKNVEPMFTCI....................................... 166
19 -23.800[TU] KOG0084 GTPase Rab1/YPT1, small G protein superfamily, and related GTP-binding proteins  ali follow..  17  10........................................................KLLLIGDSGVGKSCLLLRFADDSYLDSYISTIGVDFKIRTV-----EQDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVTYDVTD-LESFNNVKQWLNEI---DRYASENVNKLLVGNKCDLTSQKVVSTETAKAFADELGIPFLETSAKNATNVEEAFMAM....................................... 165
20 -23.700[TU] KOG0078 GTP-binding protein SEC4, small G protein superfamily, and related Ras family GTP-binding proteins  ali follow..  16  11........................................................KLLLIGDSGVGKSCLLLRFSEDSFTPSFITTIGIDFKIRTI-----ELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLLYDVTD-KKSFDNVRTWFSNV---EQHASENVYKILIGNKCDCEDQRQVSFEQGQALADELGVKFLEASAKTNVNVDEAFFTL....................................... 166
21 -23.700[U] KOG0081 GTPase Rab27, small G protein superfamily  ali follow..  16  11........................................................KFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVGPDGATGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTN-EQSFLNVRNWISQL--QMHAYCENPDIVLCGNKSDLEDQR---VVKEEEAIALAEKYGIPYFETSAANGTNI........................................... 170
22 -23.600[U] KOG0095 GTPase Rab30, small G protein superfamily  ali follow..  20  11........................................................KIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVGFMIKTV-----EINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITC-EESFRCLPEWLREI---EQYASNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDL....................................... 166
23 -23.500[R] KOG0080 GTPase Rab18, small G protein superfamily  ali follow..  18  10........................................................KILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTI-----SVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTR-RDTFVKLDNWLNEL--ETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARK............................................................... 142
24 -23.300[U] KOG0092 GTPase Rab5/YPT51 and related small G protein superfamily GTPases  ali follow..  18  22........................................................KLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTV-----CLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITN-EESFARAKNWVKEL---QRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAI....................................... 177
25 -23.300[R] KOG0088 GTPase Rab21, small G protein superfamily  ali follow..  12  14........................................................KIVLLGEGCVGKSSLVLRFVENKFSCKHLSTIQASFQNKTV-----NVEDCQADLHIWDTAGQEKYHALGPIYYRGSNGVLLVFDITD-RKSFEKVKNWVLEI---KTCLGNTAEILIVGNKIDLEEERQVTRQDAEAYAESEGALYMETSAQDNVGISDAFESL....................................... 169
26 -23.300[U] KOG0086 GTPase Rab4, small G protein superfamily  ali follow..  21  10........................................................KFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVV-----NVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITS-RETYNSLAAWLTDA---RTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKC....................................... 165
27 -23.100[U] KOG0093 GTPase Rab3, small G protein superfamily  ali follow..  16  24........................................................KILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTI-----YRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITN-EESFNAVQDWSTQI---KTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERL....................................... 179
28 -23.100[U] KOG0094 GTPase Rab6/YPT6/Ryh1, small G protein superfamily  ali follow..  13  11........................................................KLVFLGDQSVGKTSIITRFMYDKFDTTYQATIGIDFLSKTM-----YLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDVAN-RLSFLNTSKWIEEV---RNERAGDVIIVLVGNKTDLVEKRQVSIEEGDSKGREYGVMFIETSAKAGFNIKPLFRKI....................................... 166
29 -22.900[U] KOG0097 GTPase Rab14, small G protein superfamily  ali follow..  19  13........................................................KYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRII-----EVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITR-RSTYNHLSSWLTDA---RNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEA....................................... 168
30 -22.800[T] KOG4252 GTP-binding protein  ali follow..  14  11........................................................KMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQI-----QVNDEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTD-----RGSFEAVSSWREKVVAEVGDIPTVLVQNKIDLLDDSCIKNEEAEALAKRLRLRFYRTSVKEDLNVNEVFKYL....................................... 165
31 -22.700[U] KOG0087 GTPase Rab11/YPT3, small G protein superfamily  ali follow..  16  12........................................................KTVLIGDSGVGKSNLLMRFTRNEFNIESKSTIGVEFATRNI-----VLDNKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDITK-QSSFDNVGRWLKEL---REHADSNIVIMLVGNKTDLLHLRAVSTEEAQAFAAENNLSFIETSAMDASNVEEAFQTV....................................... 167
32 -22.700[U] KOG0098 GTPase Rab2, small G protein superfamily  ali follow..  17  8........................................................KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMV-----TIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITR-RDTFNHLTSWLEDA---RQHSNSNMVIMLIGNKSDLEARREVKREEGEAFAREHGLVFMETSAKTAANVEEAFIDT....................................... 163
33 -21.700[E] COG4917 Ethanolamine utilization protein  ali follow..  22  2.......................................................KRIAFVGSVGAGKTTLFNALQGNYTLARKTQAVEFNDKG------------------DIDTPGHPRWYHALITTLQDVDMLIYVHGANDPESRLPAGLLDI----------GVSKRQIAVISKTDMPDADVAATRKLLLE................................................................. 117
34 -21.500[R] KOG1673 Ras GTPases  ali follow..  14  103........................................................KISLLGDCQTGKTTFVVKYVGDEN-QSFLEMTGLNLMDKTF-----YVQGVTISFSIWDVGGDERSKDHIPIACKDAVAILFMFDLTS-----RSTLNSVFGWYSQARKWNKTAIPILIGTKFDDFVRLPPNLQWTIVTQARAYAK-----------------------------VMNASLFFSSATHNNVNKIFKFILARL.. 266
35 -20.700[R] COG3596 Predicted GTPase  ali follow..  15  36....................................................HYEPVIGIMGKTGAGKSSLCNALFAGEV------SPVSDVAACTRDPLRFRLQIGEHFMTIVDLPGDTEYAALYREQLPRLDLILWLIKADDRALATDE------HFYRQVIGEAYRHKMLFVISQSDKAEPTSGGNILSTEQKQ............................................................... 175
36 -20.500[R] KOG2486 Predicted GTPase  ali follow..  13  132...................................................ADGLPEFALVGRSNVGKSSLLNSLVRRKRLALTSKKPGKTQCI-------------NDKWYLVDLPGYNKFTKDYFLNRSTLVSVFLLVDA---SIPVKPIDLEYASWL-----GQNQVPMTLIFTKCDKRKKKKNGGKKPEANIKEFQ-----------------------DLIQGFFETTPPWIMTSSVTNQGRDEILLHMAQLRN. 313
37 -20.400[R] KOG0083 GTPase Rab26/Rab37, small G protein superfamily  ali follow..  20  470........................................................KVIMLGDSGVGKTSLLIRFRDGRYVPSYLSTVGIDFRNKVV-----VVDGTRVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDVTN-KTTYDNIRAWLGEI---REYAQEDVVIVLIGNKADCSGSE--RQVKREDGERLGR-------------------------------EHNVPFMETSAKTGNVELSFTAVARQLK. 632
38 -19.900[R] COG1084 Predicted GTPase  ali follow..  18  159...................................................DLDAFTVVIAGFPNVGKSTLLRTLTGAEPEVADYTTKGIQIGHLER---------KWKRIQVIDTPGNNIELQAMVALENIADVIMFIFDASETCGYTLESQYSLY----LGIRSVFDIPVVTVFNKMDLASAFEGRGVSKIIKKLEGLYEKETREAHDN................................................. 335
39 -18.700[V] KOG1707 Predicted Ras related/Rac-GTP binding protein  ali follow..  13  1.........................................MWMGVGDSSGSPKPIRIVVVGEKGSGKSSLIMAAARNTFHPNIPSLLPYTNLPSEF-------FPDRIPATVIDTSSRPEDKGKVVKEVRQADAIVLTFAFDR-PETLDRLSKYWLPLFRQ---LEVRVPIIVAGYEVDNKEAYNHFSIEQITSALMKQYREVETSIQWSAQRLDQAKDV------LYYAQKAVIDPVGPVFDQENNVLKPRCIAALK. 201
40 -18.600[R] COG0218 Predicted GTPase  ali follow..  15  26.......................................................PEIALAGRSNVGKSSFINTMLNRKNLARTSGKPGKTQLL-------------DDKMRFVDVPGYEKWGCMIEEYLTTRENLRAVVSLVDLRHDPSADDVQMYEFLKY-----YEIPVIIVATKADKIPRGKWNKHESAIKKKLNFDPSDDFILFSSVSKAGM........................................... 184
41 -18.000[R] KOG1489 Predicted GTP-binding protein (ODN superfamily)  ali follow..  17  337....................................................KSIADLGLIGLPNAGKSTILNKISNAKPKIGHWTTLSPTIGTVSLGFGQD-------VFTVADIPGDKGMGLEFLRHIERSNGWVFVLDLSN-KNPLNDLQLLIEEVGTLEKVKTK--NILIVCNKVDIDAEKSESFAKYLQVEKFSKSQEWDCVPISALREKT............................................ 499
42 -18.000[P] COG0370 Fe2+ transport system protein B  ali follow..  17  2.....................................................SQNTYCILGNPNTGKTSLFNALTGSYEYVGNWSGVTVEKKV---------GTLRSKTGKLIDLPGIYDLNPISRDETEKFDCMLNIVDSSQIER----------NLNLTVQLLEYGAPVVMGLNMIDVAAGRGIHLNIQNLAKKL.............................................................. 135
43 -17.800[J] COG4108 Peptide chain release factor RF-3  ali follow..  14  13....................................................SKRRTFAIISHPDAGKTTITEKVLLFGRAIQVAGTVKGRGSNISVTTSVMQFPYGDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDAA---KGVEDRTRKLMEVTR-----LRDTPIVTFMNKLDREIRELMDEVENELKIACSPIT.......................................................... 172
44 -17.100[R] KOG1490 GTP-binding protein CRFG/NOG1 (ODN superfamily)  ali follow..  17  169.......................................................RTVLICGYPNVGKSSFMNKVTRADVDVQPYTTKSLFVGHT---------DYKYLRYQVIDTPGRNIIEMCSITALAHLRAVLFFLD---ISGSCGYTIAQQAALFHSIKSLFMNKPLVIVCNKTDLMPMENISEEDRKLIEEM.............................................................. 310
45 -17.000[J] KOG0468 U5 snRNP-specific protein  ali follow..  16  129....................................................PLIRNVALVGHLHHGKTTFVDCLIRQTHPQFETMEERQSIKATPVTLVLQDVKQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAE----VMLNTERLLK-----HAVQERQAITVCINKIDRLILLPPQDAYFKLKHIVEEVN.......................................................... 288
46 -17.000[R] KOG0393 Ras-related small GTPase, Rho type  ali follow..  19  2.....................................................QAIKCVVVGDGAVGKTCLLLSYTTNAFPGEYILTVFDTYST------NVMVDGRPINLSLWDTAGQDDYDQFRHLSFPQTDVFLFALNNPASFENVRAK-------YPEVSHHCPNTPIILVGTKADLREDRDT----------IERLRESRLQPVSHTQGY-----------VMAKEIKAVKYLECSALTQI.............. 163
47 -16.800[R] COG1163 Predicted GTPase  ali follow..  18  61..................................................ARTGVASVGFVGFPSVGKSTLLSKLTGTESEAAEYTTLVTVPGVI---------RYKGAKIQMLDLPGGRGRGKQVIAVARTCNLLFIILDVNKPLHHKQIIEKELEGV----GIRLNKTPPDILIKKKEKGGI............................................................................ 190
48 -16.800[J] KOG0469 Elongation factor 2  ali follow..  16  17....................................................RNIRNMSVIAHVDHGKSTLTDSLERCITIKSTAISLKGENQFETVEVDGKKEKYNGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVS----VCVQTETVLR-----QAIAERIKPVLFMNKMDRALLLGAEELFQTFQRIVENINV......................................................... 199
49 -16.600[T] KOG1487 GTP-binding protein DRG1 (ODN superfamily)  ali follow..  19  60..................................................AKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYTTLTTVPGVI---------RYKGAKIQLLDLPGGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGF----GIRLNSKPPNIGFKKKDKGGI............................................................................ 189
50 -16.400[M] COG0481 Membrane GTPase LepA  ali follow..  16  2....................................................KNIRNFSIIAHIDHGKSTLSDRLIQTCGGLSDREMEAQVLDSMDLERERKAKDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQ--------GVEAQTLANCYTAIEMNLEVVPILNKIDLPAADPERVAEEIEDI................................................................ 150
51 -16.300[J] KOG0462 Elongation factor-type GTP-binding protein  ali follow..  14  40....................................................DKIRNFGIVAHVDHGKSTLADRLLEPPGQKQMLDKLQVERERITVKAQTAALRHRGYLLNLIDTPGHVDFSAEVSRSLAVCDGILLLVAANQGVQA--------QTIANFWLAFEKNIQIIPVINKIDLPGADIKSVETQLKNL................................................................ 181
52 -16.300[R] COG1160 Predicted GTPases  ali follow..  14  212...................................................QDKNIKIAIVGRPNVGKSTLTNRILGEDR------VVVFDMPGTTRDSIYIPMERDGQQYTLIDTAGRGKVHLAVEKFIQDANVVLLTIDARE---NISDQDLSLLGFI-----LNAGRSLVIVVNKWDGLDQDVKDRVKSELDRRLDFIDFARVHFISALHGSGVGNLFDSIKEAYACATQKMT-------TSLLTRILQMATDEHQP 410
53 -15.900[T] KOG1486 GTP-binding protein DRG2 (ODN superfamily)  ali follow..  18  58..................................................TKYGHGRVALIGFPSVGKSTLLTMLTGTHSEAASYTTLTCIPGVI---------HYNDTKIQLLDLPGGKGRGRQVIAVAKSSDLVLMVLDASKSEGHRQILTKELEAV----GLRLNKTPPQIYFKKKKTGGI............................................................................ 187
54 -15.800[T] COG1217 Predicted membrane GTPase involved in stress response  ali follow..  17  3....................................................ENLRNIAIIAHVDHGKTTLVDKLRKEAESERVMDSNDQEKERITILAKNTAIKWNGYNINIVDTPGHADFGGEVERVMSMVDSVLLVVDAQDGPMPQTRFV---------QKAFKAGLRPIVVVNKIDRPGARPDWVIDQIFDL................................................................ 147
55 -15.300[K] KOG1534 Putative transcription factor FET5  ali follow..  14  6.........................................................AFVCGVASSGKSTFCGALMSYMKSVGRSCDYGPNGGLINLDWLNEEIGDYDEDYLIFDMPGQPALIRHLQVTLNFRPCAVYLLESQFLVDRTKFFAGVLSAM---SAMVMMEVPHINLLSKMDLLKDNNNITKAELKRFLNTDPLL--LTGEINETTNPKFHELNRCIVQLIDDFNMVNFLPLESGNEEVSRVLSYIDDATQ. 254
56 -15.200[R] COG1159 GTPase  ali follow..  16  11.........................................................IAIVGRPNVGKSTLLNKLLGQKI------SITSRKAQTTRHRIVGIHTEGPYQAIYVDTPGNRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKL---------RDGKAPVILAVNKVDN--VQEKVDLLPHLQFLASQMNFLDIVPISAETGMNV........................................... 162
57 -15.100[S] KOG4273 Uncharacterized conserved protein  ali follow..  16  2....................................................ESRPGVLVVGSSGVGKRTLLSRLLSVEFEDSSESSSQTEVHGWTINT-----KYYTADVSVCISHICDEYSLPNLPNSHPLVALVMVFDLSE-----LSTLVALQDWVSHTDINSFDILLCI-GNKVDRVPHHLAH--------------DEYRRRLLKASDPSRDLYSDIDDFGISETEGSSLLGSEDASLDIRGACLEWCSEN... 181
58 -15.000[J] COG5256 Translation elongation factor EF-1alpha (GTPase)  ali follow..  16  1.............................................MKIMASQKPHLNLITIGHVDHGKSTLVGRLLYGEIPAHIIEEYRKEAEQVTIDLAHRKFETDKYYFTLIDAPGHRDFVKNMITGTSQADAAILVISAREGEGVMEQTRE--HAFLARTLGVPQ---MVVAINKMDATSPPYSEKRYNEVKADAEKL........................................................... 175
59 -15.000[J] KOG0460 Mitochondrial translation elongation factor Tu  ali follow..  16  49..................................................RKKPHVNIGTIGHVDHGKTTLTAAITK-MDYSQIDKAPEEKARGITISSAHVEYETANRHYAHVDCPGHADYIKNMITGAATMDGAIIVVSATD---QMPQTREHL-LLARQVGVKQ----IVVYINKVDMVEPDMIELVEMEMRELLSE............................................................ 200
60 -14.800[J] COG0480 Translation elongation factors (GTPases)  ali follow..  14  1.............................................MARINPLEKVRNIGIAAHIDAGKTTTTERILFYSGIIHKIGEVHEGTAVITITAAAISTSWKDYQINIIDTPGHVDFTIEVERSMRVLDGVIAVFCSVGGVQPQSETV---------RQADRYKVPRIAFINKMDRTGARVHEQMRDRLRANAIAIQ.......................................................... 163
61 -14.700[R] KOG1533 Predicted GTPase  ali follow..  14  36.........................................................VLVIGAPGAGKSTFCAGLTDIFSQTKRPFGLGPNGALKNCNWLLQKIEANHKKYLIIDCPGQLELYKSEGELWKVIRFLLHLADSLYCSDPSKFISVALSTL---ATMVTMEMPQVNCLSKADLFSEDGTYDLEFFSHLPDVNR---LLDLLNEVPGLEKYRKLNEAICGVISDFDLVSFVPLAVENKEMMKVIQMVDAANG. 282
62 -14.400[J] KOG0466 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  14  34...............................................EVISRQATINIGTIGHVAHGKSTVVKAISDPSCPRPECYRSCGSSMPDEFPTDIPGTKGNVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNE----QPQTSEHL-AAIEIMKLKH----ILILQNKIDLVKERQAKEQYEQILAFVQGT-------------------------------EGAPIIPISAQLKNIEVVCEYIVKKIP. 244
63 -14.100[R] COG0536 Predicted GTPase  ali follow..  21  160.......................................................ADVGLVGFPSAGKSSLISVMSAAKPKIGDYTTLQPNLGVVNVGHE---------TFTMADVPGGKGLGLDFLRHIERTSVLVHVVDTATMDPG-RDPISDIEALEAELAAYQSALPRLVVLNKADVPEA---EELAEFLKEDIEKQFGWPVFIISAVARKGL........................................... 329
64 -14.100[P] COG2895 GTPases - Sulfate adenylate transferase subunit 1  ali follow..  13  23..................................................QHKSLLRFLTCGSVDDGKSTLIGRLLTRQIYEDQLSSLHNDSKRITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKH-------LVVAINKMDLVDYSEETRIREDYLTFAGQL........................................................... 194
65 -14.100[J] KOG0052 Translation elongation factor EF-1 alpha/Tu  ali follow..  17  1................................................MGKEKVHINIVVIGHVDSGKSTTTGHLIYGGIDKRTIEKFEKEAQEITIDIALWKFETAKYYITIIDAPGHRDFIKNMITGTSQADCAVLVVACGEFEAGISKNGQTREHALLAQTLGVKQ--LIVACNKMDSTEPPFSEARFTEITNEVSG............................................................ 176
66 -13.900[J] KOG1145 Mitochondrial translation initiation factor 2 (IF-2; GTPase)  ali follow..  20  178....................................................PRSPVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLP------SGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADD----MKQTVESI------QHAKDAQVPIILAVNKCDKAEADPEKVKKELLAYDVV-----------------------------EDYGGDVQAVPVSALTGNLMALAEAT...... 338
67 -13.900[J] KOG0465 Mitochondrial elongation factor  ali follow..  15  68....................................................NKLRNIGISAHIDSGKTTFTERVLYYTKRIKAIHEVRGRDNVGAKMDSMDDKEGKNYHFNLIDTPGHIDFTIEVERALRVLDGAVLVVCAVS----VQSQTVTVDR-----QMRRYNVPRVTFINKMDRMGSIEKGPVPENLKPLMEEKRQLLIETLADVDDEMAEMFLEEKEPTTQQIKDAIRLMGSALANTGIQPVLDAIVDYLNP 348
68 -13.600[O] KOG0448 Mitofusin 1 GTPase, involved in mitochondrila biogenesis  ali follow..  13  72...................................................SRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAY---RDDLVLVDSPGTTELDSWIDKFCLDADVFVLVANSESTLMNTEK------HFFHKVNEWLSKPNIFILNNRWDASAS-EPEYMEDVRRQHMERC........................................................... 260
69 -13.600[J] COG0012 Predicted GTPase, probable translation factor  ali follow..  15  2........................................................EIGVVGKPNVGKSTFFSAATLVDVEIANYPTIDANVGVTYAQNYEYREGLALIPVKMIDVAG-RGLGNKFLDDLRMASALIHVVDVTGKTDAEGQPTENH-DPIEDIEFLEREIDYWIY------------GILSKGWDKFAKRIKLQRIKLESAIAEHLSGIGVTENDVWEAMHRLGLPSDPTLWSQEDLLAFASEIRRINKP 216
70 -13.600[R] COG5258 GTPase  ali follow..  17  103..................................................EPPPTVTVVALGNVDAGKSTLVGVLTTGEVLTGRTSAVSLNHGLIDPLDEAEVYKRSDKLVLLVDVGGHERLRTALRGLFSSQPDYVMLVVAAN-SGVQKMTKEHLGIAVA-------GIPVFVVVTRIDITPSEVFQKTVEEVVRILKMPGVSKIPYIIKDTNDVVLAAKAMPAGRVAPV-----FYVSSVTGHGLDLLLRFLSLLPRR 330
71 -13.300[TU] KOG1954 Endocytosis/signaling protein EHD1  ali follow..  17  45.......KKKNKEVLETVSEGLRKIYKQKLLPLEEFHKFHDFHSPALDDPDFDAKPMILLVGQYSTGKTTFIRYLL-ESDFPGIRIGPEPTTDRFIAVMHGDEEGSIPESVTIVDTPG--DFTGVLEWFAERVDRIILLFDAHKL-----DISDEFKRCIEALAGNEDKIRIVL--NKSDMVDHQQLMRVYGALMWSLGKVFKTP....................................................... 281
72 -13.100[L] KOG1532 GTPase XAB1, interacts with DNA repair protein XPA  ali follow..  19  38...................................................KKKPIIIIVVGMAGSGKTSFLHRLVFDSKSHGYVVNLDPAVMSLPFGANIDIRDADQLDYVLVDTPGQIEIFTWSASGAIITEAFTYVVDTPRSSSPITFMSNMLYAC---SILYKTRLPLVLAFNKTDVADHKFALEWMEDFEVFQAAIQSDNSYTATLANS---------LSLSLYEFYRNIRSVGVSAISGGMDGFFKAIEA.... 282
73 -13.000[DZ] COG5019 Septin family protein  ali follow..  18  88...............................................RCVRQGFNFNVLVLGESGSGKSTLVNTLLNRDVYPPTQKSLTGDFGVINSSAVEIVENGISLQLNVIDTPGFGDIEGRYDQYLELVHACIFFIQPTGHAISAMEL-RVMLAL-------HEKVNIIPIIAKADTLTDDELNFTKEMILRDIQY............................................................ 266
74 -12.900[J] KOG0459 Polypeptide release factor 3  ali follow..  13  97..................................................NKKRHLNVVFIGHVDAGKSTIGGQILFGQVDDRQIQKYEKEAKDKTVEVGRAHFETESTRFTILDAPGHKSYVPNMISGASQADIGVLVISAREFETGYERGGQTREHVQLAKTLGVSK--LIVVVNKMDDPTVNWSKERYDEIEQKMVPFLKASGYNTKKDVVFLPISGLMGKNMDQRMGQEICPWWSGPSFFEVLDSIEIPPRDPNGP 330
75 -12.800[J] COG0050 GTPases - translation elongation factors  ali follow..  15  5...............................................KFERTKPHVNVGTIGHVDHGKTTLTAAITSARAFDQIDNAPEEKARGITINTSHVEYDTPARHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATD---PMPQTREHI-LLGRQVGVPY----IIVFMNKCDM---VDDEELLELVEMEVREL........................................................... 157

FFAS is supported by the NIH grant R01-GM087218-01
1 3 5 0 9 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.