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Query: [D] KOG0267 Microtubule severing protein katanin p80 subunit B (contains WD40 repeats), from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSLCGHTSPVDSVAFNSEEVLVLAGASSGVIKLWDLEESKMVRAFTGHRSNCSAVEFHPFGEFLASGSSDTNLRVWDTRKKGCIQTYKGHTRGISTIEFSPDGRWVVSGGLDNVVKVWDLTAGKLLHEFKCHEGPIRSLDFHPLEFLLATGSADRTVKFWDLETFELIGTTRPEATGVRAIAFHPDGQTLFCGLDDGLKVYSWEPVICRDGVDMGWSTLGDFCINEGKFIGCSYYRNSVGIWVSDISELEPYGAVSEDKNECMVKRFSVLNDQSERMGSGPRGSVSPDYETREIKNIYVDSTGGNLNVAQNPGSLKATLPLESGKVATMVSEKQNAAYFGPAGDKYSSTSRDSDSGEESSYSERESIPFSRTKSGMLLRPAHVRKTLAKFEESKQSAVVQSATRKKSGLAVEEEPQTQNAFLSEQNASKPFDAEDSIIKGITNKFEKALSSEPPTDEANRMFLKPPRIHRSSNSKYNDTRRAMSADPATFGKGGMENSGDVEDIPSKTERVLSREKPGDEQKNTEYPSGSRELNPVKIVEGVNVVSGRTRSLVEKFERGEKTTHTEGASTTIEQNNNAVQEDPRKTSRQTGETPVISTRRARSTPARVMPIVLNRDSNVTSDEPPLTQPARTSSFPVMPVILNQASNVTYDEPSVALTQESRTSHARILPVTFNQATNITSEEASVTLRRQRRNSAARVRPVLLSQATSHECPVTSVRPLRTSPARVMPTKLNQSVNMTSDTSHIASMHRVSPTQMLATPTVIDQVADMTLDETHATQIQPACDNMPQKEEPNISDREDDSDITENLMLTHNEFLSTLQSRLTKLQIVRHFWERSDVKGAIGALRKLTDQSVDVISILTEKIEILTLDMFSQLVPVLTSLLGSRTERPVNVSLDMLLKLVAVFGTVIRSTVSAPRIVGVDLHANERNLPNLFCGTAQDSKNSSSSRKKRRSNNKKGSRTKPSSSRTIAASKTKNLast
1 -218.000[D] KOG0267 Microtubule severing protein katanin p80 subunit B (contains WD40 repeats)  ali  100  1MSLCGHTSPVDSVAFNSEEVLVLAGASSGVIKLWDLEESKMVRAFTGHRSNCSAVEFHPFGEFLASGSSDTNLRVWDTRKKGCIQTYKGHTRGISTIEFSPDGRWVVSGGLDNVVKVWDLTAGKLLHEFKCHEGPIRSLDFHPLEFLLATGSADRTVKFWDLETFELIGTTRPEATGVRAIAFHPDGQTLFCGLDDGLKVYSWEPVICRDGVDMGWSTLGDFCINEGKFIGCSYYRNSVGIWVSDISELEPYGAVSEDKNECMVKRFSVLNDQSERMGSGPRGSVSPDYETREIKNIYVDSTGGNLNVAQNPGSLKATLPLESGKVATMVSEKQNAAYFGPAGDKYSSTSRDSDSGEESSYSERESIPFSRTKSGMLLRPAHVRKTLAKFEESKQSAVVQSATRKKSGLAVEEEPQTQNAFLSEQNASKPFDAEDSIIKGITNKFEKALSSEPPTDEANRMFLKPPRIHRSSNSKYNDTRRAMSADPATFGKGGMENSGDVEDIPSKTERVLSREKPGDEQKNTEYPSGSRELNPVKIVEGVNVVSGRTRSLVEKFERGEKTTHTEGASTTIEQNNNAVQEDPRKTSRQTGETPVISTRRARSTPARVMPIVLNRDSNVTSDEPPLTQPARTSSFPVMPVILNQASNVTYDEPSVALTQESRTSHARILPVTFNQATNITSEEASVTLRRQRRNSAARVRPVLLSQATSHECPVTSVRPLRTSPARVMPTKLNQSVNMTSDTSHIASMHRVSPTQMLATPTVIDQVADMTLDETHATQIQPACDNMPQKEEPNISDREDDSDITENLMLTHNEFLSTLQSRLTKLQIVRHFWERSDVKGAIGALRKLTDQSVDVISILTEKIEILTLDMFSQLVPVLTSLLGSRTERPVNVSLDMLLKLVAVFGTVIRSTVSAPRIVGVDLHANERNLPNLFCGTAQDSKNSSSSRKKRRSNNKKGSRTKPSSSRTIAASKTKN 974
2 -75.600[A] KOG0306 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  12  18.VIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSLRVWDIAYLQEIEDPEEPDRVVNLAVDKTGRILACHGTDSVLELFCILSKK----EIQKKMDKKMKKARKKAKLHSSKGEEEDPEVNVTIGGHRSDVRTLSFSSDNIAVLSAA-ADSIKIWNRSTLQCIRTMTCEYALCSFFVPGDRQVVI------------GTKTGKLQLYDLASGNLLETIDAHDGSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVK-IWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLILEEEREMEREAEYEESVAKEDQPAVPGETQGDSYFTGKKTIETVKAAER--------------------------------------------------------------------------------------------------------------------------------------IMEAIELYREETAKMKEHKAICKAAGKEVPLPSNPILMAYGSISPSLEIFKGI-KSSELEESLLVL----SYVPDILKLFNE-QLGSDVELICRCLFFLLRIHFGQI-----TSNQMLVPVIEKLRETTISKVSQVRDIGFNMAGLDYLKR----CEAKSEVMFFADATSHLEEKKRKRKKREKLILTLT...... 943
3 -71.900[K] KOG0263 Transcription initiation factor TFIID, subunit TAF5 (also component of histone acetyltransferase SAGA)  ali follow..  18  319.TFHHTNNNMNCAEFSPDSTMIACGFQESYIRLWSIKDSDGSVRLLSHSGPVYGTTFSPDNKYLLSCSEDASARLWSVDTKTALVAYKGHTGPVWDVAFGPFGHYFATASHDQTAQLWSCDHIYPLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCRLWDVHRGHSVRVFNGHTQPVTAVAIAPDGHTMASADSEGIHLWDIGTGRRIKTMRGHRGNISLSFSRESTVLVSGGSDCTVRAWDVFKTNYNN----PVSSSLTGSVVTPFSAKTSTFNETSPDQMVALYTKQTPIFNVSFTRRNLCLAISVS....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 643
4 -70.900[S] KOG0271 Notchless-like WD40 repeat-containing protein  ali follow..  15  100.SIPGHGEPVISAQFSPDGRGLASGSGDQTMRIWDIELELPLHTCKSHKSWVLCIAWSPDATKIASACKNGEICIWNAKTGEQIKTLKRHKQWITSLAWQPTCRLLASCGKDGNIFIWDTVQGTVVRCLSGHTASVTCLRWGGEGL-IYSGSQDRTVKMWRADDGVMCRNMTGHAHWINTLALNTDYALRTSCFEPSRCIKPDTVEECQKVAQTRYEAA--LEIAGGERLVSGSDDFTLFMWNPKETK-----INRMTGHMQLVNQVVFSPDTRYIASASFDKSVSLRGHVGPVYQVAWSADSRLLVSGSADSTLKVFELKTKSLYYDLPGHG----------DEVFTVDWSPEGTKVVSGGKDKVLKLWR........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 472
5 -70.500[U] KOG0276 Vesicle coat complex COPI, beta` subunit  ali follow..  17  10.KLAQRSERVKSVDLHPTEPWILASLYSGTLCIWNYQTQVMAKSFEVTELPVRSAKFVARKQWVVAGADDMYIRVYNYNTMDKVKVFEAHSDYIRCVAVHPTLPYVLSSSDDMLIKLWDWEKGACTQIFEGHSHYVMQVTFNPKDNTFASASLDRTIKIWNLGSPDPNFTLDAHQKGVNCVDYFTGGDYLITGSDDHAKVWDYQTKSCVQTLEGHTHNVAVCFHPELPIIITGSEDGTVRIWHATTYRLEN----TLNYGLERVWAIGYIKSSRRVVIGYDEGTIELGTCDLYPQSLKHNPNGRFVVVCGDGEYIIYTALAWRNR----SFGSGLEFVWSSEGECAVRESSSKFGGTLLAMCSSDFICFYDWAECRLIQRIDVTVKNLYWADSGDLVAIASDTS.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 485
6 -70.500[Z] KOG0318 WD40 repeat stress protein/actin interacting protein  ali follow..  11  18.LPRTQRGQPIVLGADPKGKNFLYTN-GNSVIIRNIENPAIADVYTEHSCAVNVAKYSPSGFYIASGDASGKIRIWDTVNKEHLNEFQPIAGPIKDISWSPDNQRIVAVGEGRFGHVFMSETGTSVGEISGQSKSINSADFRPARPFIVTGSEDNTIAVFEGPPFKFKMTKQDHSRFVQAVRYSPDGKFFASAGFDGVFLYDGTSSELVGEFPAHKGGVALAWKPDSTQLLTCSGDKTCRLWTVESRELVSE----VMGTTVDDQQVSCLWQGDNLITVSLSGVITVKGHNKPITVLGLSDDRSTIYTGSHDGVVTNWNSGSGTNDRTGTGHGNQINGIAAWGDFVYTLAILRNENIIALACIKELTLVQDQKKIFSL-PIKYEASSIAVNADTSDVAVGGDDQKLHIYTLKGGVLEP----------KVELDHLGAVTDVSYSPDLKYLVACDAHRKVVLYSVEEYKPAHNKGFHSARVNTVAWSPNSLLVASGSLDTTIIIWSVANPAKHTIIKNAHPQSQITRLVWLDNNTVISTGQDCNTKVWHVENI...................................................................................................................................................................................................................................................................................................................................................................................................................................... 608
7 -70.200[S] KOG0308 Conserved WD40 repeat-containing protein  ali follow..  12  24.HEYSNRSAVSALQYDAQNGRLFTGGSDTIIRTWSVPHHKDAGSLEQHTDWVNDMILCGHGKILISASNDTTVKVWNIERDNFIDCIRTHKDYVSCLAYAPIVEKAVSASFDHNIFVYDINANKTVNNLIGCKDSIYSLATTPNLSLVLGAGTEKCIRLFDPRTNEKIMKLRGHTDNVRALVVNDDGTRALSAGSDAIRLWDIGQQRCIATCIAHEEGVTLQVDSSFTTVYSAGKDKMVVKTPLYDFT----KSQLLFKEEAPVKKLLLSEKDNSLWVGTWKSDIKRGDEDGPSTSNANHSVSASSSPPVTFKYIRVKDQKGQQSTPELVIPGAPAI---------KKHAMLSDKRHVLTRDSDGNVALYDVLAARKIKDVVDENSRQVYIPSWFVVDSKSGMLQITLDELDDDNDRETKQIIVNYGGMMLRSLFERWPPCKMTNVDAADADDVQKATLNFISLPEHTPLIICEGNGRPLYRLLVGDAGKEFEANELAQIAP........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 571
8 -69.800[A] KOG0291 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  15  303.RKEQRDVQLTAANYNTRTKVLVVAFSSGAFYLYELPDVNMIHSLSISDYPISAALFNCTGDWVALASREGQLLVWEWQSEQYIMKQQGHSSEMTCIAYSSDGQFIATGGEDSKVKLWNTQSSFCFVTFSEHTSGVTGIQFSRNKKFLVSSSLDGTVRAFDVNRYRNFRTFSPNPAQFSCVAVDYSGELVVAGGQDVIFLWSVKTGKLLEIISGHEGPVSIAFSPTSSTLVSGSWDKTVKIWNCLESN----SEHETIDAVSDVTNVTFSPSGEEIAVATLSGNITINAQANYFSTIEYSADGECILAAGKSANICIYHVREAILLKKFEITQISRKHLSEFGNMALVEEREE------LEGGRVAIRLPGVQRGDMSSRQEVRVFSVKFSPTGQAFAAAGTEGLC------------IYALDKGVVFDPFDLSLEVTPKAVHESLKQQNYTKALVMSLKLNEPN............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 796
9 -68.300[S] KOG0295 WD40 repeat-containing protein  ali follow..  19  59.LQRKVNDLESKLQESQREINHGAPTRDKRQAADWIPRPPETQKLTGHRLPITRVIFHPLWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVYTFRGHNDWVRMIRISNDGTLFASASLDQVTVWSFATKSAKLVLRDHEHAVECVEGNSTHILFSGSRDRSIKAWNINTGDVL----FTLLAHENWVRGLAFHPKGKYLISVADDKTLAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVWECR............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 404
10 -67.800[A] KOG0285 Pleiotropic regulator 1  ali follow..  13  72.SEKTAPLKALALPGPKGSKELRKSATEKALVVGPT-LPPRDLNNTGNPGKSTAILPAPGSFLSTAALMERMPSRWPRPPWKNYRVLQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKVIRSYHGHLHGVYCLALHPTLDVVLTGGRDSCRVWDIRTKMQIFVLPHDSDVFSVLARPTDPQVITGSHDSTIKFWDLRYGKSMA----TITNHKKTVRAMALHPKENDFVSASADNIKKFSLQRDIINAVAVNEDG-VMVTGGDKGGLWFWDWKSGHNFQRAETIVQPGSLESEAG--IYAACYDQTGSRLVTCEGDKTIKMWKEDED-----ATPETHPLNFKPPKEIRR................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 476
11 -67.800[A] KOG0319 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  13  105..KTIHTAPILVMEFNEEGHLLATGSADHIVKVWNLTEQQCTHTLKGP-SVVSAILFGKHEK-LVVGYIEGQLNLYNIAPKKLVNTWKSHNSHITALLQVPDSRVVVALSRDQTMSIHETETQETLRVLPLYES-IEGGAIGHNGN-LFTVGEEGVVKEFVIETAKLVRKKRIASSNLDHLAYDVVSNRFLAISAEQLIILDFENLKIARQIVGFHDEICCLLGKDESHMAVASNTSEIRLYNTKTLDCQLI----RGHTESVLSVVSPTWDTSLLASCSKDNSIIFTGHANTVTALAISNTGRALASVSTDCTIKLWGLGVSTKLKEVKIDAEKDSTMVAHGKDVNCVDISESDALIATGGMDKLVKLWQVDTHKTLSGHRRGVGDVKFAKNSHKLASCS-----------GDMTIKIWNISEKSCLQTISGHSCAVFRVIFARNDSQLISADSAGIIKIWTIKTADCECSIDAHTDKIWSLSKNHNESEFVTAGTDGRIV........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 632
12 -67.700[T] KOG4378 Nuclear protein COP1  ali follow..  10  1.........MMSNLVEPSWRLLAASG-GDTVKLFDVSADSVLSYTPSPGCAVNSVKWNHTNLVVASTGEDKKISLWRKNGQSLGTGGDSAEECLSAISFSKKGRYICSGGTGQIVKIWDLQRKLCIKKLKGHTSTITGVMYNCKDEHLASVSVGGDLIVHNLASGARATELKDPNGQLRLLDYSRSSRLLVTAGDDGVHLWDTTGRSKMSWLKQHSAPTAGVFSPSNEIIASVGMDKKLYTYDSGSRRSSSC------------------------------------AYEAPFSSLAFGDNGYILVAGTSNGRVVFYDIRGKPQPVTVNSEDVTSLSWQTSKPVIVNEKNYTSEMALLGSTVEDSVVIPDPLPS-----TTPSASQSAMAPGSRGVSASTVNASSVEQTPNRNHLWPS---------GPLGRLHALRANDSYNDDMGVFSPIIDVSSVEKWADSEGYNNKDHLVVDNKPSSLLFPSSSKGYSFGDNGSKEHPIFDWKPSSTSKQDDPRAAFSSFGSITPTASSKSEDSALTPPEAWGGDKFSEKFNQLANEKFSDKFSHLHAPSRLAVSSTGASTSGSMFSSSRDFPLSHGQTNFANASLEFPRIRDFSSTFETSSTQTDNNLPSSPLFTKGITAPGNIDSLRLSPNFTRRFSTYAERISTTSSFSDGASLSLGGSPKIKKTGSETREEVLNHLLARPETVVATEAGAMPLMNGGLKQSQTDQQQVM--------------------------------------------------------GSSNFTLQLFQRTLEGTDSFQNSIHDDVRNLEILRQF-HEMEMSKVLSSILENQAEQMKELKLLRKENQELRQRL......................................................................................................... 787
13 -67.200[B] KOG0639 Transducin-like enhancer of split protein (contains WD40 repeats)  ali follow..  12  436LAGIPGGKPAYSFHVTADGQMQPVPFPPDALIGPGIPRHARQINTLNHGEVVCAVTISNPTRHVYTGG-KGCVKVWDISHPGNKSDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLATPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKY-----QLHLHESCVLSLKFAYCGKWFVSTGKDNLLNASKESSSVLSCDISVDDKYIVTGSGDKKATVYEVI............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 769
14 -67.000[R] KOG1539 WD repeat protein  ali follow..  12  140LQLTGKFTPTSIVHPDTYLNKVLVGSQEGPLQLWNINTKKMLYQFKGWGSSVTSCVSSPALDVVAIGCADGKIHVHNIKLDEEIVTFEASRGAVTALSFSTDGRLLASGGSFGVISIWNLNKKRLQSVIDAHDSSIISLNFLANEPVLMSASADNSLKMWIFDTNRLLRFRSGHSAPPLCIRFYSNGRHILSAGQDRFRLFSVIQEQQSRELSQRHISRAKKLRLKEEELKLKPVVSFDCAEIRERD------CNVVTCHMDTAEAYVWRLQNFVLGEPIKGVFVSRNHLLLAILACAISACGNFAVVGTAGGWIERFNLQSGISRGSYFDMSEKRR--YAHDGEVIGVACDSTNTLMISAGYHGDLKVWDFKKRELKSDVGCSLVKIVYHRVNGLLATVA-----------DDFVIRLYDVVTLKMVREFRGHTDRITDLCFSEDGKWVISSSMDGSLRIWDVILAKQIDGV-HVDVPITALSLSPNMDVLATAHSDQNGVYLQSMFSGLPSVESYASGKDVVNVKLPSVSALTSSEADDDMDRQVLENSEALQASSFSISQKQIPELVTLSLLPKSQWQSLINLDIIKARNKPIEPPKKPEKAPFFLPSIPSLSGDILFK---------------------------------------------------------------------------------------------------------------------------------------------------------------------ANDSEADGENEENNKKDQNSMKNFDALESPFSKHLKSSW------DSKHFLDFTNYMKSLSPSALDMLRMLEIIDE--EFILIGQLLDYFINEVSCKNDFEFMQAV--VKLFLKIHGETIRCHPSLQEKA--KLLETQSLV.............................................. 908
15 -66.200[T] KOG0279 G protein beta subunit-like protein  ali follow..  21  10.TMCAHTDMVTAIATPVDNDVIVTSSRDKSIILWKLTKGVAQRRMTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLATGESTRRFVGHTKDVLSVAFSTDNRQIVSASRDRTIKLWNTLGEYTISEADGHKEWVSCVRFSPNTLVIVSASWDKTVKVWNLQNCKLRNTLAGHSGYLNTVAVSPDGSLCASGGKDGILLWDLAEGKKLYSLEAGSIIHSLCFSPNRYWLCAAT-ENSIRIWDLESKSV-------VEDLKVDLKAEAEKTDGSTGIG--------NKTKVIYCTSLNWSADGNTLFSGYTDGVIRVWGIGR............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 325
16 -65.500[R] KOG0286 G-protein beta subunit  ali follow..  16  10.EAEQLKKQIADARKACADVTLAEL--VSGLEVVGRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSRKVSRELSAHTGYLSCCRFLDDNNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDAAKLWDVREGTCRQTFTGHESDINAIFFPNGEAICTGSDDASCRLFDLRADQ--ELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 340
17 -64.500[R] KOG4227 WD40 repeat protein  ali follow..  10  6.GLGGSMRSVVGFLSQRGLHGDPLLTQDFQRRRLRGCRNLYKKDLLGHFGCVNAIEFSNNGQWLVSGGDDRRVLLWHMEQAKPIQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVILHDVESSETLDVF-AHEDAVYGLSVSPVNNIFASSSDDGRVLIWDIRESP-PFCLANYPSAFHSVMFNPEPRLLATANSKEVGLWDIRKPQSSLLRYGGNSAMSVRFNSNGTQLLALRRRLPPVLYDIHSRLPVFQFDNQGYFNSCTMKSCCFAGDRDQYILSGSD-FMVLKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSPYKQPGCTGDLDGRIEDDS--------RCLYTHEEYISLVLNSGSGLSHDYANQSVQ-------EDPRMMAFFDSLVRREIEGWSSDSDSDLSESTILQLHAGVSERSGYTDSESSASLPRSPPPTVDESADNAFHLGPLRVTTTNTVASEDAASRQQRLSALRRYQDKRLLALSNESDSEENVCEVELDTDLFPRPRSPSPEDESSSSSSSSSSEDEEELNERRASTWQRNAMRRRQKTTREDKPSAPIKPTNTYIGEDNYDYPQIKVDDLSSSPTSSPERSTSTLEIQPSRASPTSDIESVERKIYKAYKWLRYSYISYSNNKDGETSLVTGEADEGRAGTSHKDNPAPSSSKEACLNIAMAQRNQDLPPEGCSKDTFKEETPRTPSNGPGHEHSSHAWAEVPEGTSQDTGNSGSVEHPFETKKLNGKALSSRAEEPPSPPVPKASGSTLNSGSGNCPRTQSDDSEERSLETICANHNNGRLHPRPPHPHNN-----GQNLGELEVV--------------AYSSPGHSDTD----------------------------------------------------------DNSSLTGTLLHKD-----C--CGSEMACETPNAGTRSRAVHGHSG-LKRQRIELE---TDSEN 933
18 -64.400[B] KOG0273 Beta-transducin family (WD-40 repeat) protein  ali follow..  20  174.VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIWTE-NGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMT-FASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMLKIWSMKQDACVHDLQAHSKEIYTIWSPTGPMLASASFDSTVRLWDVEQGVCT----HTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHI-QGTGGIFEVCWNARGDKVGASASDGSVCVLDL.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 522
19 -64.300[D] KOG0642 Cell-cycle nuclear protein, contains WD-40 repeats  ali follow..  15  458.TLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDGLIQGWNTTNPNLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVKELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLENSSCQINRVISHPTLSISITAHEDRIKFYDNNTGKLIHSMVAHLEAVSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAKV............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 778
20 -63.400[S] KOG0772 Uncharacterized conserved protein, contains WD40 repeat  ali follow..  12  76.MQQSEAGPSSSRAEGPEDSDDSDFDETEAISIIKLIPAACEAKISHGTQAISALRVEPPGVRFASGGLDYYVKLFDFQKMDMSELLPAESHVINSLAFSPNGETLVVASGEAIIRLLDRAGKQWLNITKGHTATVNCVEFNPLNKEFISCSDDGSLRLWNLDDHKVIKGANGKRVSPQVCTFSPDGKWIAAGCDDGVQAWKYGSQYVYLVRKAHNGSISIAFSPDSKRLLSRGFDDTLKMWSLDNPK-EPLLVKTGLENAFKSTDCGFSPRAEVVFTGTSDLVYKIDYPGISCHRIQWHPRLNQIIAGLSDGTIHVYYDQTMSQRGVMVTKPLKRNRASEVVRELSLEMFQPRGEEGEEKEVTGWRIKKYLRMQRPEFRKPADMPINGKSANGRVAASGGSLHSYLAKQIGTARNAEFLKDTD--------------------VRASILKHAKDAEENPLYIDKAYRKTQPKKIFQETAVEPEDQDDEELQPVFKMPRT.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 619
21 -63.400[R] KOG0288 WD40 repeat protein TipD  ali follow..  17  226.RIHAHEGGCGSIVFEYNSGTLFTGGQDRAVKMWDTNSGTLIKSLYGSLGNILDMAVTHDNKSVIAATSSNNLFVWDVSSGRVRHTLTGHTDKVCAVDVSKFSRHVVSAAYDRTIKLWDLHKGYCTNTV-LFTSNCNAICLSIDGLTVFSGHMDGNLRLWDIQTGKLLSEVAGHSSAVTSVSLSRNGNRILTSGRDNHNVFDTRTLEICGTLRASGNRLRSCISPDDDYVAAGSADGSVHVWSLSKGNIVS----------------------------------ILKEQTSPILCCSWSGIGKPLASADKNGYVCTWT............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 515
22 -63.400[BK] KOG1063 RNA polymerase II elongator complex, subunit ELP2, WD repeat superfamily  ali follow..  11  14.IGAGCNRVVNNVSWGASG--LVSFGAQNAVAVFCPKTAQILTTLPGHKASVNCTHWLPTSKYLLSGDSDGIIILWELSTLNVLQLPLSHKKGVTCIMVSETDAMFASASSDGVVNVWDVSFPVCLDSICVDTKAIVTLSLNPGRFALALGGLDNKIKLYSGERTTSVCELKGHTDWIRSLDFSLPLHMLVSSSQDKIRIWKLVLVSVESVLIGHEDWVSVEWQPPVISILSASMDKTMMIWRPEKKTVNVVCVGELSHCALGFYGGHWSPNSLSILAHGYGGAFVPSGHFAAVTDVTWARTGEYLLSVSQDQTTRVFSAWKNDEGNEAEDEHWHELAVHGHDINCVAMVQGKGNHRFVSGAEEKVVRVFEAPLSFLKTLNHTCAGGEGSFPEDLQADVQVLGANMSALGLSQ----KPIYLHSSSEPLERNGGGEGLDTFETVPEAAPAELKEPPIEDQLAFHTLWPESHKLYGHGNELFSLCSDHKGNLVASSCKAQSASWLWEVGTWKAVGRLQSHSLTVTHLEFSYDDTLLLSVSRDRHFSVFSIQR....................................................................................................................................................................................................................................................................................................................................................................................................................................... 678
23 -62.100[A] KOG0265 U5 snRNP-specific protein-like factor and related proteins  ali follow..  19  13.AQEAKRSKNDLMAYTNRDKALLESGVRRTSNLQ-----APIMQLEGHEGEIFTAEFHPEGELLLSSGFDRQIYIWQVYEDENVMAMSGHSGAVMEAHFTPDGSHIFTCSTDKTLAFWDIATGQRQRRFKGHGNFVNSVQGSRRGQLLCSGSDDRTIKIWDARKKHAAHTLESP-FQVTAVCFGDTGEQVISGGIDNVKIWDIRKQAVLHHLRGHSDTIGMSLSPEGDFILTNAMDNTLRVWDVRGERCVKVFQGHQHNFEKNLLRCAWSPGSDKITSGSADRHVKLPGHNGSVNAVDFSPKEPLILSGSSDKTLYLGEIDE............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 347
24 -62.000[S] KOG0316 Conserved WD40 repeat-containing protein  ali follow..  16  13.ILKGHEGAVLAARFNGDGNYALTCGKDRTIRLWNPHRGILIKTYKSHGREVRDVHVTSDNAKFCSCGGDRQVYYWDVSTGRVIRKFRGHDGEVNAVKFNDSSSVVVSAGFDRSLRVWDCRSHSVEPVQIIDTFLDTVMSVVLTKTEIIGGSVDGTVRTFDMRIGREMSDNLGQP--VNCISISNDGNCVLAGCLDSLRLLDRTTGELLQVYKGHISKTDCCLTNSDAHVIGGSEDGLVFFWDLVDAKVLS----KFRAHDL-VNSIDVDFYLRLLK----------------------------FFVAGDKRELPPEGRLYVDFFGRWYNSCLEKM---------KKQQILTSIDFVIYVSNSPFFFYYR........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 342
25 -62.000[S] KOG0296 Angio-associated migratory cell protein (contains WD40 repeats)  ali follow..  17  56.GFFEHKDSVFSVSINPVHNLCASGGGDDLGYIWDITTGEQICQLTGHKDSIVAIDWSFDGTYIATGGMDSQVRLWKSSTGFEFITAFETVDEIVWLSWHPKGLFLAAGCNDGSIWMWSLPSGKVVQVMYGHTAPVNAGKFIPPGKRLATVDDSGTLIVWNPATGAPECRMSETAAGWTSFDCNAEGNVLFLGGSSGVKVVNINSSHILASLEAQTESVEAILCTALPICACASVDGTVALYDSASLKFRKS------PHEQAVIDCKFLPNTPYLLTACADCVIEYTGHQEPILCMAITPDGKRVVTGSDDTELLVFDCEH............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 399
26 -61.700[A] KOG0284 Polyadenylation factor I complex, subunit PFS2  ali follow..  13  128.AMNKVKCPVYSVCWSPEGKRLITGCQTGEFTLWNGTAFNFETILQAHDSAIRALKWASNEQWLLSADQGGYVKYWQPNMNNAHMFSAHKDEAIRGLAFAPTDVKFATASDDGTARVWDFARYTEERVLRGHGAEVRCIDWHPTKGLIATGSRDQPVKIWDPKSGSCLATLQEHKSSVMAVEFNKNGNWLLTGGRDHVKMYDIRMMKEMRTYRAHKKEVSLAWHPIHELFVSGGGDGSIVYWMVDGEKEIGL---LEHAHDQAIWSMKWHPLGHILATGSNDNNTNMIGHLDKEREPRMAPPKPSIETQETYRPDTFIPGMG--------LDEHLYEQLNRDHNMMTTDSTLLVPDDLTRQNFAPMIGAKRTLIKKKAQRQFERMWNNSKGIGAGSDDFTTMKGGLGREDAEGAQFGP----SKSFLGPPTTGGSLLGPSQPRPQEFRSVPPPQQQQG.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 599
27 -61.600[R] KOG0315 G-protein beta subunit-like protein (contains WD40 repeats)  ali follow..  13  35....VETSQVNALDRTPDKTRLAACGYQ-CIRLYDLESNAPVINFDGVQKNVTRLGFQEDGNWMFTAGEDHHVRIWDMIAAPHCSRIFDCEAPVNAACLHPNQVEIAMGSQNGSVFLWDVKSERHERIVPEVDASIQDVAISPDGRYLAAANNKGNCYIWSLTSQRPNRKIPAHSRYILRCKFSPDSRLLLTTSGDGVCIWKTDDFSKWRELCIENYWVDAAFSADSKWLFTASSDGIARLWKLQTKSSIR----DYTGHTKAITALSFKDEIPVKSTNISDVQSSADNPPGTNNLAFFETVGRVAMNPYMGNTTTELN............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 362
28 -60.800[JT] KOG0643 Translation initiation factor 3, subunit i (eIF-3i)/TGF-beta receptor-interacting protein (TRIP-1)  ali follow..  11  4ILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALL-KTNSAVRTCGFDFGGNIIMFSTDKQMVSFFDLDNNEPYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRI---------------------KFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 325
29 -60.600[A] KOG0640 mRNA cleavage stimulating factor complex; subunit 1  ali follow..  18  101.YVTSHKQACRAGAFSCDGSLVATGSVDASIKILDVERMPVIRTLYDHTDEVSYLEFHPKEHILASASRDGTVKLFDIAKPSVAHKVFTDCEPVLCLSFHPTGDYVAIGTEHNVLRVYDVATTQCFVSAQQHKAGVTCVKYSPTGKLYATGSYDGDIKIWDGISGRCINTIAEAHGGICSLEFTRNGKYLLSSGMDSVYLWELCTSRPIQTYTGAGTT-AVFNHTEDYVLFPDEATTSLCSWNSRNGCRL---------------------------------TLNSLGHNGPVRYITHSPNGPAFLTCSDDFRARFWYRRANNQ......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 424
30 -60.300[A] KOG0272 U4/U6 small nuclear ribonucleoprotein Prp4 (contains WD40 repeats)  ali follow..  22  256.SQVGDTRPVSSAAFSEDSSLLLTSSWSGLCKLWSVPDCELKQTLRGHASYVGGVALRPGVKAMASGGHDGAVKLWGFNNEESIADITGHMPHVSKVAFHPSGRFLATACYDSSWRLWDLEQKTEVLHQEGHAKPVHCLSYHSDGSVLVTGGLDAFGRVWDLRTGRCIMFLEGHLGAVFGVDFSPNGFHIATGSQDNCKIWDLRRRQPVYTIPAHTNLISDVYQQEGSFLVTCSYDSTTKIWSNKTWQP----------------------------------LKTLQGHDNKVISVDIAPNSQYIATTSFDRTFKLWSPDS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 553
31 -60.300[S] KOG0283 WD40 repeat-containing protein  ali follow..  13  350.RVADKDVSDGSTDSPKKGKDHKHGKANEWVKVRELSALHMCQEIQAHEGAVWTIKFSQDAHYLASGGADRVIHVWEVQECELMSMNEGSLTPIHPSLCDSSGNEITVVEKKKKGKGSSGRSDKPVCSLKGHLDAILDLSWSKSQL-LLSSSMDKTVRLWDIETKTCL-KLFAHNDYVTCIQFSPDENYFLSGSLDAIRIWSIQDRHVVEWSDLHEMVTAACYTPDGQGALIGSHKGICRAYDTEDCKLSDVQSNKKSQAKRKITSFQFSPVNPEVLVTSADSRIRIFRNTCSQLSASYSQDGKYIICASEDSQVYLWKNDFHRTRSTLTTQSHEHFDVSAAVPWHGHVRGEPPPVQIHSKRHSKRISTSSQPSSTISSPTKEETSATG--------PTTSNRNKKSGLPPMPKKAATKSQIQPEEEAGPELGSSESFRSSMNSSEQ---HSSRFGESPSINTSSRLSSWSWFDSGGHGPQTIQPTAWGMVIVTATVHGEIR........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 885
32 -60.200[R] KOG1524 WD40 repeat-containing protein CHE-2  ali follow..  11  9.RKTRHTEMVCGVGWIGTEA-ILSAADDHVFLLTNTATNESQQILNMPETFFRSQTKGGQNDVFAVSTSDGKINILS-RNGKVENMVDAHNGAALCARWNSDGTGLLSSGEDGFVKMWSRSMQVAPIKWKAHDGIILCCDWNPTSDLIVTGGEDLKFKVWD-GFGQILFNSSVHDYPITSISWNTDGTLFAVGSHNILRLCDKSGWSHSLEKMNAGSVMALSWSPDGTQLAVGTAAGLVFHAHIIDKRLTYEEFEIVQTQKTVIEVRDVSSEVSRETLETKERISTPTMIEYNERTVNIIVQCEKIFLVSDGMTITIFTY-EGRKLINLNPPGQVM-----ALLDERKIDLANDTLVVRDRADNKVLHFFDPTTGKAQGDHEHDIVELTVNQCGPL-------NDRNVAFRDQIGAVHIAMVKTFGVSQRMVKIGSLVEQLVFNDVTNMLC-GISEGKIAVWPLPNVAFHDRN--LQKSLIQKNIGSVGKFPQLANFAGNTIVIRKSDGCLLPTGILPFYGTLITMASQSKWDQAIRLCRSIGND............................................................................................................................................................................................................................................................................................................................................................................................................................................. 612
33 -60.100[S] KOG0282 mRNA splicing factor  ali follow..  18  283.VWSGHTKGVSAVRLFPLGHLLLSCSMDCKIKLWEVGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNR-KVPYCVKFNPDEDLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIEPSMHSMPAVTLSPNGKWLACQSMDNILIFGAQNRFRLNKKKIFKGACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYS----RFKAHDKVCIGAVWHPH-----------------------------ETSKVITCGWDGLIKLWD............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 579
34 -59.400[A] KOG1272 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  11  32.QESDVELETKVKKYLRGEGANLETLKDKKLKTQLASREKLYGKSAKAAAKIEKWLLPAEAGYLETEGLEKTWRVKDILSSRNQYDIVLPDFGPYKLDFTASGRHMLAGGRKGHLALLDMMNMSLIKEIQKERGPVARLRFLKNHFLLASVNMSGQLHYQDVTHGGMVASIRTGKGRTDVMEVNPYNSVVGLGHSGGVTMWKPTSQAPLVQMQCHPGPVSVAFHPNGHLMATSGKERKIKIWDLRKFEEV------QTIHSFHAKTLSFSQKGLLAAGTGSFVQIHSMVKGYQIEKVMFRPYEDVIGIGHSMGWSSILIPGSGEPNFDSWVANFETSKQRREKEV----------HSLLDKLPPETIMLDPSKIGAMRPSRRKEKPSRGIEAEKEVAIEAAKSTELKNKTKGRNKPSKRTKKKKEMVENAKRTFPEQEHNTAIKKRRIVEDAAAELPTS................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 540
35 -59.200[I] KOG0301 Phospholipase A2-activating protein (contains WD40 repeats)  ali follow..  10  24.VIEAHKSDTKALAVTQGGC-LISGGRDETVKFWAKKGKKTHAFEQPKGITVNSIAYAEDGWRLFVGRRDGTIAVFGPSQAEPYAIFNEHKQNVCCLHINEKATHMLSGSWDSNVIIWPITESFTTIVCPGHTLSVWALASFPDLNTYLSASADKTIRMWF--GDTTLSVFKGHTDVVRALVVLSSSHFLSAGNDGHIIHWDVASASILRKFATQAHEFIYSMTLSDSHILTTGEDGTLEFWAIDGGKDGNLAIVSEA---------------------------VIQLPTTNTWDAKVLLNSD-IAVAGSDGRIYIMTTDKN-----------------------------------------------RKADDDILDAFDAEVVAKLTAKTERMKQEEHETVTIK---------VDIDDRPTQLNLKYKKGTDPGLCAQEFLSENNLPIHYLEEITRFIKDRIPEARAFDLKSGKDYALGVNFGKGEPDKQMPFNVNESP-AAQRFVERHQLPVSVIPSLAGMISQEMDKLSKGAASAQSGYEDPFTGPGRYVPQGSSNSGGHGADPFTGSGRYVPQASNSSGFDTGFSGDPLTGDGGYRASAPENTGSHAVPLSSLPQN----KKKPRGPLVPVPDFYIIGLAGKGEKAIAKLKELNEKQDAFQLNPDQINGLEELFVLPTSSNYSSEVTQSAFEMSLQWPVEHLTPVLDFLRIALTHHSLNSYFCDRERGQELVGRLIAILVSDPADVALKVLVCR------------------------------------------CIANAFSHPVGRNLFASTELSTLAPLVVR-EKTVLQMSAATA--LANWSL----LLQQSEQCEQLGPKEDLLRAILNGIESVDSF--YLGEDAIIRLLQALVTVMASVIRLAKNRNIDAVSNDSGKNIRDIVEMTYAV.................................. 858
36 -58.600[DK] KOG0973 Histone transcription regulator HIRA, WD repeat superfamily  ali follow..  10  2.TFVGHDTSILAIDCHPSGKKFITCGSNGLVVVWNAEP-PKLLFQVESQSQSNSCRWSPDGKRFAFGSDDSSVSVWEYVGLKECCVLRGHSMEVLTVEWSPNGKYLASGSIDYRIIIYNARKPDRITVLNDIQLPVKGLSWDPIGKYLASLEGDKKLRFWATDSWQCVKSVTIEETMLTRLDWSPDGKYLMTPAAVRIKLIQRQTWKSDQFLAGHHKGTTCVAMPQLTCAAVGSRDKSISIWVFP----------------------------------GTLKPLFVINNIFNHTVMDFAWCGRNLLACSQDGTVKVIHLSESVIGEMISNEAMSDLCYQIYSIRPPRYELTDKEEDESQDSFNLSDLSSSANNASFVTCPEDVLIKRKKLVAAQQSSDIQLTKSMEDNSKENESKNSEKTMMEERNKQIDVRKDGKRRIQPVFCGTTTADPMTSLSSEGKKTVAPPPAKRKALAPAVPAKKGEVDLEDSSDSDDDDEEEEEDMEISDIESVRNKKRKVPATTSQPMLALDLKKPALRPMEPKSLKTQEGTVLMEAPEQQPKLSQHVVDRKGMFVEIDNRWKHGGVETTQIKLIKKKQQTAENEDDMMDGERRVNHECLWMAVLGSPVIIVAANKHNVVLGCGDKCLRVYRTFCGTHIVSLRLDSLPVLIGVTEHAAYALTENGRLSTWNLKLGKAVVTRQPLFDCVEASTDNSLISADVSETGVPLIVFSNGSIFTFNVSLSCWIQAITTNVLGRLTSPISDAQLSCSNGTTNSAGPLVRLLKRMRKQATAPGVAPQVVKAVKESQLEQLLHCAEQLGNQTMLMLYVETLCEGG-------SEKKLKNILNDLSR----PMQVCGLALYDDVTRMIKLKQPAIAAR-IVAGVAASTTTKSLF....................................................................... 927
37 -58.000[R] KOG0289 mRNA splicing factor  ali follow..  15  133.TLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQKLSASIPGILALDLCPDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVETSGCSLTCAQFHPDGLIFGTGTMDSIKIWDLKERTNVANFPGHSGPISIAFSENGYYLATAADDSSVKLWDLRKLKNFKT----QLDNNFEVKSLIFDQSGTYLALGGTDVQIHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 504
38 -58.000[R] KOG0645 WD40 repeat protein  ali follow..  16  1...SGHTGRLWSVAAHPMLPLFATSSQDKSVRIYNSNTYNLVHVIDGHTRSIRRVAWRPIERVLAVASFDSVVSINEKDDWECTAALEGHENEVKCIAWSCNGNYLATCSRDKSVWIWEATEDDCLAVLQEHTQDVKVVTWHPTEDLLVSGSYDNSICFWRDDDWALTCQLQGHTNTVWALAFSPNGNTLASADNDGVFLWIKISSNQTSLPHIHKGAVTISWMNDAT-LCSAGGDGKIVVYQREKHD----------------------------ALWHVAYEQDHAHGVYEINSLEYLRDDR-LLSGGDDGECRVWSFK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 322
39 -58.000[S] KOG1409 Uncharacterized conserved protein, contains WD40 repeats and FYVE domains  ali follow..  26.RITGHVARINDVILLSKDEGVWTASDDRSVRLYLKRDNDQFWPSHFMPVAPTSLYYSEETYKLLVGLINGNVYEFDFNSMTESRKWTCHAGPISGLGFALSSELIFSCSRDKSIVWHCSENSN---KMGSYLLENSCTAMVIDLPFVFVGDHGGHVTVLRIVDNQLVSKLSAHTNAITSLTWDGNKKVLYSGSSDHIIMWDIGGGREAYELNGHNGKVTTLAAPAAKRLFSADEHGKLMCWDMNCKRVET--PEWKTSDCCQKCNQPFFWNLQAMWQRKVVGLRQHCRTCGSAVCGSCCDNWTTYPPMGYETKIRICNDCNARMKDNPQNFNLTPLAIPHEIHTITAMHLQETLGLLVTSGQNRVIMIWDVRSVCSAPSGS................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 414
40 -57.400[S] KOG0293 WD40 repeat-containing protein  ali follow..  17  227LVENSLHIQRDSCVFHNTLDSDLSLYSDHQCGKHQI-PSQTAQILESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEISADSLKHTLVGHHKPVIAILWSPDDRQVLTCGAEEVIRRWDVDSGDCVHMYEKGGISPISCGWYPDGQGIIAGMTDRSICMWDLDGREKECWKGQRTQKVSDIAMTDDGKWLVSVCKDSISLFDREATV--ERLIEEEDMISFSLSNDNKYILVNLLNQEIRLWNIEGDPKIVSRYKGHKRSRFIIRSCFGGYKQAFIASGSEDSQVELPGHAGAVNCVSWSPTNLMLASASDDGTIRIWGLDRINQQNQKQGSSSNGVIHRCNGN...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 589
41 -57.300[R] KOG2096 WD40 repeat protein  ali follow..  10  2...........DSVLVVGIASVILGALIAVLFFGSYFRKRTSEVQSMAKAEPQDPIRNPKSNHPAPKKNHPKSQASDKNQNKDLNTLKGHGDAVTGLCFSSDGKSLATACADGVIRVFKLDDARFLRINLPAGGHPTAVAFADDASSIVVGKLPLPSIKWDHHHIHEKRSVLTISGATATYGTADGSVVIASCSEGTIVLWHGKTGRNLGHVDTNQLKNMAAVSPNGRFLAAAAFTADVKVWEIVYQKDGSVKEMQLKGHKSAVTWLCFSPNSEQIITASKDGSIRVGGNPLHYDRLSLCPEGKILAASH-GSTLQWLCAETGNVLDTAHEGDITCISWAPKAITVG----ERHAMVLGTSGDDKKVKLWEAPKSQSL.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 454
42 -57.200[S] KOG1407 WD40 repeat protein  ali follow..  17  15.EYQGHKKKVHSVAWNSNGTKLASGSVDQTARIWNIESKAKDLELKGHTDSVDQLCWDPKHSLVATASGDKSVRLWDARSGKCTQQV-ELSGENINITYKPDGTHVAVGNRDDELTILDVRKFKPLHRR-KFNYEVNEIAWNMPGDFFFLTTGLGTVEVLSYPSLKPLDTLTAHTAGCYCIAIDPKGRYFAVGSADSVSLWDISDMLCLRTFTKLEWPVTISFNYSGEYIASASEDLFIDIANVQTGR-----------------------------------TVHQIPCRAAMNSVEWNPKYNLLAYAGDDKNPKYNTDEGVFRIFGFESS.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 315
43 -56.900[Z] KOG1523 Actin-related protein Arp2/3 complex, subunit ARPC1/p41-ARC  ali follow..  13  3.LHQFLLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQKDGVPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFEAENSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVEFGGSGTGGWVHGVSFSASGSRLAWVSHDSVSVADASKSVQVSTLKTEFLPLSVSFVSENSVVAAGH-DCCPMLFIYDDRGCLTF----VSKLDIPKQSIQRNMSAMERFRNEDRNTALETLHQNSITQVSIKQDCRKFCTTGIDGAMTIWDFKTLESS........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 363
44 -56.800[S] KOG0310 Conserved WD40 repeat-containing protein  ali follow..  14  20LLDEDEPAVVSSVRISPKKPYHVATTSSVRLTLYDTVVCEPLNLFSRFKKGVCSIDFRHDGRLLAIGGDEGKVRIFDVESKVALRVMQASQSTVKSVHFSPRGDTVFSMADDGKIKQYRVADTAYIIEIQAHEDAIRCGAVSSNDHIVLTGGYDHKVRLWDIRSKEKSLEL-DCEHPVESVLFLPGEQLIATAAGPIVKIWDTTTGRQLTALQAHYKTVSLRLATNSTCLLSAGIDRRVNAFRTTNYSLI-----NSWSMPSPVLDIDVSRDDQTMAIGMGNLLALYAAIEDKRSLIRTSAPPVKLVEKDRDMQKVDVVAKNADKLKPKIDGMLSNFKHAAVIKLLF-------GGKFRSAMDTAVVSYLRVMRGAIHRALAGQERSV.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 422
45 -56.700[ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA cleavage factor II complex, subunit SWD2  ali follow..  14  18.IFRENTDKINAIDFAPNGEHLISCSEDDQIVIYDCEKGTQSRTVNSKKYGVDLIHFTHANNTASSTKVDDTIRYLSLHDNKYLRYFPGHTKKVISLCISPVEDTFLSGSLDKTLRLWDLRSPNCQGLM--HLSGRPIAAYDPEGLIFAAGVNSESIKLYDLRSFDTFKLNQEKECDWTGLKFSRDGKTILISTNGSIRLVDAFHGTPLQTFTGYPNPIEASFSPDSQFIFSGSTDGRVHIWNADTGNKVS---------------------------------VLNGDHPGPVQCVQFNPKYMMLASACTNMAFWLPTSEEG........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 316
46 -56.600[A] KOG0268 Sof1-like rRNA processing protein (contains WD40 repeats)  ali follow..  11  14VRETKLDLQRVPRNYDPALHPFEVPREYNATKLERVFAKPFLASLDGHRDGVNCLAKHPEKATVLSGACDGEVRIWNLTQRNCIRTIQAHEGFVRGICTRFCGTSFFTVGDDKTVKQWKMDGPGYGDELHTILGKTVYTGIDHHWKEAVFATCGQQVDIWDEQRTNPICSMTWGFDSISSVKFNPIETFLLGASDRNIVLYDMRQATPLKKVILDMRTNTICWNPMEAIFTAANEDYNLYTFDMRALD---TPVMVHMDHVSAVLDVDYSPTGKEFVSASFDKSIRITKRMQHVICVKWTSDSKYIMCGSDEMNIRLWKANASEKLGVLTSREKAAKDYNQKLKEKFQ----YPHIKRIARHRHLPKSIYSQIQEQRIMKEARRRKRIKHSKPGSVPLVSEKKKH......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 439
47 -56.400[BL] KOG1009 Chromatin assembly complex 1 subunit B/CAC2 (contains WD40 repeats)  ali follow..  11  8.IAWHNKEPVYSLDFQHGTARLASAGVDTNVRIWKVEKGEFLSNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKVNDNTVVKTLRGHLEDVYDICWATDGNLMASASVDNTAIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYVATLSCDRVLRVYSIQKKRVAFNVSSMKSFFRRLSFTPDGSLLLTPAGCVSGENVMNTTYVFSHLPCPGKATLAVSLPYRLVFAVASEDSVLLYDTQQSFPF----------------------------------GYVSNIHYHTLSDISWSSDGAFLAISSTDGYCSFVTFEKDELGIPLKEKPVLNMRTPDTAKKTKSQTHRGSSPGPRPVEGTPASRTQDPSSPGTTPPQARQAPAPTVIRDPPSITPAVKSPLPGPSEEKTLQPSSQNTKAHPSRRVTLNTLQAWSKTTPRRINLTPLKTDTPPSSVPTSVISTPSTEEIQSETPGDAQGSPPELKRPRLDENKGGTESLD....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 558
48 -56.300[J] KOG0650 WD40 repeat nucleolar protein Bop1, involved in ribosome biogenesis  ali follow..  12  393.YLRERFLRCLDLYLCPRAKRVKLNIDAEYLIPKLPSPTVESMVYRGHTDLVRSVSVEPKGEYLVSGSDDKTVKIWEIATGRCIRTI-ETDEVVRCVAWCPNPKLSIIAVATGNSNAEADEQEKGVRVVITHFKPIRQVTWHGRGDYLATVMPEGANRIHQLSKRRSQIPFSKSKGLIQFVLFHPVKPCFFVATQHNIRIYDLVKQELVKKLLTNSKWISGMIHPKGDNLLVSTYDKKMLWFDLDLST------QTMRLHRNAVRSVAFHLRYPLFASGSDDQAVIVKRDEFGVLDVNWHPVQPWVFSTGADSTIRLYT............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 784
49 -55.900[S] KOG0281 Beta-TrCP (transducin repeats containing)/Slimb proteins  ali follow..  17  198.RIQCRSENSKGVCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGL--MVTCSKDRSIAVWDMASATLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQY--RDRLVVSGSSDNIRLWDIECGACLRVLEGHEELVRCIRF-DNKRIVSGAYDGKIKVWDLQAAL-------------------------DPRAPASTLCLRTLVEHSGRVFRLQF--DEFQIISSSHDDTILIWDFLNVPPSAQNRSPSRTYTYIS.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 507
50 -55.500[S] KOG2106 Uncharacterized conserved protein, contains HELP and WD40 domains  ali follow..  13  123LKLEGYRGRRNNLYLLPTGETVYFIA--SVVVLYNVEEQL-QRHYAGHNDDVKCLAVHPDRITIATGQVAGTVRIWDSVTLNTLHVIGFFDRAVTCIAFSNGGTNLCADSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGEITSLLLDTRRKLPLIRSTRKAKVVLCVTFSENGDTITGDSSGNILVWGKGTNRISYAVGAHEGGISPLMLRDGTLVSGGGKDRKLISWSGNYQKLRK----TEIPEQFGPIRTVAEGKGDVILIGTTRNFVITQGHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGHRPVWDKIIE-----------DPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNG-------RKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVESDGTDINAVCRAHEKKLLSTGDDFGKVHSYPCSQFRAPSHIYGGHSSHVTNVDFLCEDSHLISTGGK................................................................................................................................................................................................................................................................................................................................................................................................................................................. 707
51 -55.100[A] KOG0299 U3 snoRNP-associated protein (contains WD40 repeats)  ali follow..  13  136.LRGRHMRPLVGVVAYENF--VYSADKSGLIQKWEALQEKDTENRNDHVKEITCLAISNDGRWIVTGGLDHRIVIRDSVTLEPQHCWKHHRDAVMGLAMRRGTNEMFSCSADRSIKVWSLDQMSYIETLFGHQDVIFGVDALARERCVSVGGRDRTSRLWKIVEESQLKATAGYMEGSVDCVAMIDEDHFVTGSDNGIALWSVQRKKPLFTYPLAHGLDSLAAIPYSNLFASGSWDGNIRLWKIAEGLFEPLTIATPLSVYGCINSLSLSLQGKGK-----------------------QSEVRVFAACGRETRVGRWKTLRGIPNSGFFNIPLTVIPSVTDGDEID................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 523
52 -55.000[R] KOG0646 WD40 repeat protein  ali follow..  12  2.................EITVIASSSIDEGIGSWDLKTGTEQLQFKPCASPAHGLTAVGESSQLSARNTSGSIFYWSWTKPQ-AEVKSYPVEPIKALAANNEGTYLVGGGISGDIYLWEVATGKLLKKWHGHYRSVTCLVFSGDDSLLVSGSQDGSIRVWSLIRTLYEHNFNEHTMSVTDIVIDYGGCVIISSSEDTCKVWSLSRGKLLKNIIFPSVINALALDPGGCVFYAGARDSKIYIGAINATS-----------------------------EYGTQVLGSVSEKGKAITCLAYCADGNLLISGSEDGVVCVWDPKSLRHVRTLIHAK---------GSRKGPVNNIQIVRKTIVANSNKTQVSWKSRGALIPPPLEKYERPVEDTMDGIVTVDPPPFSDVPVYSSFLSADL-IDEQVKELQQQGSAATEMEMERLKLEYKR............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 409
53 -54.800[R] KOG1334 WD40 repeat protein  ali follow..  17  272.LLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFSGHDINVIQAKFFPNDSTLAMCGHDGQVRVAELINASNTKRVAKHRGPAHELALEPDSYKFLTSGEDAVVFTIDLRQDRVVTRENDKKVGLYTISMNPANYQFAVGGHDQFVRIYDQRRIDKKENYCDFPTNITCVVYSHDGTELLASYNDEIYLFNSSLSDGAQYVKRYKGHRNNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQF----EGDRGDIVNCLEPHPYLPVLATSGLDQHVRITGLKDVIKKNKQERDEDNLNYTDSFDNRMLRFFVRHLLQRAHQPGWRDHGAEFPDEEELDESSSTSDTSEEEGQDRVQ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 677
54 -54.600[R] KOG2394 WD40 protein DMR-N9  ali follow..  13  172.SIHFSNSNPMCHAFAKDGHDLLIGLNSGDVYTVSLRQQLQ-GSVNNRQDRCTSISWVPSTFPAIRDPTQFSVDKAKYSKSNPVARWHICQGSINSIAFSNDGAHLATVGRDGYLRIFDFLTQKLVCGGKSYYGALLCCSWSMDGKYILTGGEDDLVQVWSMEDRKVVAWGEGHNSWVSGVAFDSNWSSPNSDGSGE---------------------------HVMYRFGSVGQDTQLLLWDLEMDEIVV----PLRRAPGGSPTYSTGSSAHWDNVIPMSPIIAHRVHTEPLSGLMFTQES--VVTACREGHIKIWTRPSESETQTNSS-------EANPTTALLSTSFTKDNKASLSSKIISGSTFKQ........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 556
55 -54.400[R] KOG2055 WD40 repeat protein  ali follow..  12  176.PKSLKSLFKSSVSYINQSSKLLAPGTINIKRLKDANFQA------PSHSGIRCMSIHPYFPLLLTCGFDRTLRIYQLKVNPLVTSLHLRSSALQTALFHPDGKRVIAAGRRKYMYIWDLESAQVQKVQENFQPSMERFHVDPTGKYIALEGRSGHINLLHALTGQFATSFK-IEGVLSDVLFTSDGSEMLVLSYGAVWHFNVEQRSVVRRWQVQDGTTHFCLDPSNKYLAIGSKSGIVNIYDLQTSNADAAPKTTLDNITFSINSMSFSQDSQVLAIASRGKK-TSATPLGRVTCLAFGKGGE-LCVGNEAGRVGLWKLAHYDLKFVPDKIINWEIRLGKFGYVLLGIQ--------LILHVDVVI............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 555
56 -54.400[S] KOG0321 WD40 repeat-containing protein L2DTL  ali follow..  17  122.CLMMLNQLPFCLGFANNESLLAVCTETGALELFDSRSARRIHGWLAHNNAIFSVNFSKDDSLLATSSGDQTSKVFDLSTQQCITRLGYHSHSVKQVNFCNDSPNLVSCSRDGSIIFWDMRTHGITHENSGRDCSITSATWLPQSTVISSCSANSALKLWDLRTVHTVRTTSKRDFGVTNVCTSPDGERIYAASRDSIYEYSSRHLNS-PRLRISSFYVKLACSPDGATLACGGKTSGVVVFDTTRN--------------------------------CSSSAMLTGGHTKDVTAVDWSSEGQ-LASISDDGSVRVWNSSLHGSAANLNFSEIFYWGFSEK........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 490
57 -54.100[R] KOG1273 WD40 repeat protein  ali follow..  13  17IEEYLEHGVIKCVAFNHRGSLLAAGCADGGCVIWDFETRGIAKEIRDNSAAITSVSWSKYGHRLLVSAADKSLTLWDVSTGEKIARTINPPFSPAAACFNKCGDLVYIGNSKGEILIVDYKSVRVLALVSSGAAPVKNIVFSRNGQYLLTNSHDRTIRIYENLLPAKNKMKTVTKMHWKAPCFSGDGEWVVGGSACKIYIWD-RAGHLVKILEGPKEALDLAWHPVHPIIVSVSLAGLVYIWAKDYTE------------------SAFAPDFKEL-----------------EENEEYVEREDEFDLIPETEKVKVLDVNEDEEVDIDTVEKFSDSDMSVEELRYLPAEPIPD---------------TNDQQDNLVESIKLIEGQISASPASEEAGQNGHHASSPQAGKKDSNS.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 472
58 -52.100[S] KOG0294 WD40 repeat-containing protein  ali follow..  12  2................PPEMEIIEATNEELLLGFKLIKSELKQTFADSSYARSITSLAVQWPWVASGGTDGRIFVYDMRTRKQSQIILSHAGRVNTLKFTPDLSLLLSGSDDGHMIATRVGSWTKEYDWKAHAGAVTHVSCHPSSKLALSLGGDQVLNTWNLVNGCVAHKTNTLDFQTGCLSWSKQGDHFTLSGPLVLEIWGIENAHVMRRIE-MPSKPICITWLDGNECLTGLDNGNIAWISLKDEDDTPPT--FILAHEVRVKAIAYL--------------------------------NEFLATVSIAGQIKVWKIDMETRKLEE-------IARSFMDCRPTDLGLLDLRQFGNVRPVEQRTKVEEKPKAKVKPAAPRGFVTIEYEQDKKLDAEKKKEKKKNKKDEE----------SSEESNSSEDKENDDFSDSDSDVSSDHGHRKRKPMKREQQPTPASKGKAKQQKKK................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 434
59 -52.000[U] KOG1332 Vesicle coat complex COPII, subunit SEC13  ali follow..  14  8.VDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGLIADLRGHEGPVWQVAWAHPGNILASCSYDRKVIIWREENGTKSHEHAGHDSSVNSVCWAPHGLILACGSSDGAISLLTYTGEEVKKINNAHTIGCNAVSWAPAVKRFASGGCDNLIKLWKEEEDGEEQKLEAHSDWVRDVAWAPSTSTIASCSQDGVFIWTCDDASSPKLLHKFNDVVHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 322
60 -51.400[T] KOG1354 Serine/threonine protein phosphatase 2A, regulatory subunit  ali follow..  13  23.DDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKYLKSLEIEEKINKIRWLPQKNQFLLSTNDKTIKLWKVEASPRRIFANAHTYHINSISINSDYETYLSAD-DLRINLWHLEITDRSANMEELTEVITAAEFHPNSNTFVYSSSKGTIRLCDMRASALCSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNENRPVETYQVHEYLRECCWNGSDSVVMTGSYNNFFRMFDRNTKR----DITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDDFNKKILHTAWHPKENIIAVATTNN-LYIFQDKVN........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 447
61 -50.600[U] KOG0277 Peroxisomal targeting signal type 2 receptor  ali follow..  17  11.MLRTPGRHGYAAEFSPLPGRLACATAQGTLLILDPDEGLRLFRSFDWNDGLFDVTWSENNEVLITCSGDGSLQLWDTAKAAPLQVYKEHAQEVYSVDWSQTRGLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPIPGCFASASGDQTLRIWDVKAAGVRIVIPAHQAEILSCDWCKNENLLVTGAVDCLRGWDLNVRQPVFELLGHTYAIRVKFSPHASVLASCSYDFTVRFWNFS---------------------------------KPDSLLETVEHHTEFTCGLDFSLQSPQVADCSWDETIKIYDPACLTIPA....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 323
62 -50.000[U] KOG0771 Prolactin regulatory element-binding protein/Protein transport protein SEC12p  ali follow..  11  10.NLQTYGVPIYAVDWILEEAVRSKITKDQDDDDDDGSSSSSYIVLSGGGGEGRS---IPNVILICRVDLHTNS------SEQPIGRRVIGTDLPYRMAIHPRQGGLICALPENIIEDDNEEESEKVVKELKDVGQQLSLSFNQDGTVLATGAEDGTLRVFEWPSMKTLLNESKTHASVKSLTFSESGKFLVSLGAPLCRVWDVNASAAIASLSKEKDEMSCRFSVDNSVAANTQRGGSIITWDTTSWRRRS---SKLIKRNNSISAFNVSADGKLLAVGTLEGDVLIKAHLGLVTALTFSPDSRCLVSVSFDSRARLTVIKQKGEKRRVVAALLFVLVYVVLYYLMVAMGIIH............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 383
63 -49.900[DO] KOG0305 Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits  ali follow..  19  162VTIDEDKGPVTSINWTQDGLDLAVGLDNSEVQLWDCVSNRQVRTLRGGHE-SRVGSLAWDNHILTTGGMDGKIVNNDVRIRSIVETYLGHTEEVCGLKWSESGNKQASGGNDNVVHIWDRSLAQWLHRFEEHTAAVRALAWCPFQASLLAGVGDGKIKFWNTHTGACLNSVETGSQ-VCSLLWSQSERELLSSTQNQLTLWKYPSMSKMAELNGHTSRVFMAQSPNGCTVASAAGDENLRLWNVFGEPPK-----TTKKAASKKYPELFSHVNSLR.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 444
64 -49.900[R] COG2319 FOG: WD40 repeat  ali follow..  13  189....RDDFYTSLLSWSPKGDLAIGLA--ENIYLWSKELGP-TRVLEESIYDVSSVAYSYNGDILAVGRVDGTLQFWQDNERV-PRISIHHPGDIGVLAWKPETNRLLVGKGNGNIFVYDIIAVLVATITNAHDEQVCGLTWNHDGSQFASGGNDNRVCLFKGSDLRQPLYVWQQNAAVKALSFCPWQRSLLATGDKHIRFYNCFNGKKIDELYCGAQITSIHWSPKYREFSVTTVQHRFAVYSWPQLE--CLVSVLPSVPDIRCVHSVLTSQLNETTGRC--------------------EMTDSIIIASSNETIKFFDLSEESSWHNSRVLTDSQILEMLEG---------------IDGKIDSHLR.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 535
65 -49.600[R] KOG2919 Guanine nucleotide-binding protein  ali follow..  121.SSTEAQHYTKGCYWSPDGTCLLVPVHLDGMHVIEMPSDLYSADTVQEGGTVYDCVWYPHMNLWLATRQHEPIHMWDAFDGSLRCSYSGYDMAAISLAFSHDGEQIYAGY-KRCIKIFDTSRPGRFCDDYPVKFAISCIAQTTAHPTLTCGNWHGYIQHFDLRCSHPLFTLGGHKGGITQLRYGEFGNFSGARKCDKILQWDMRYKQPLVELQRHVDTNQRILASDSNWLASGDTRGFVNVWDLKKYG----DPSVLPLHSDCCNGVALNPAMPILATSSGQFHFVTLNGTETTELPAPADVNQNQKEVLYENAVVMWWCGQTG.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 487
66 -49.400[S] KOG4328 WD40 protein  ali follow..  19  209.VARVVPGRIFVVQFLPNVKMVAAGDKLGNVGFWNLDCGNEIYLFTPHSAPVSSIVFQQNSSRVISSSYDGLIRLMDVEKSV-FDLVYSTDEAIFSLSQRPNDQSLYFGQDYGVFNVWDLRAGKSVFHWELHERRINSIDFNPQNHVMATSSTDGTACLWDLRSMGKTLSTVNHSRAVHSAYFSPSGLSLATTSLDNIGVLSGANFENTCMIYHNNSKFKAVWGWDDSYIYVGNLSKKIDVINPKLKRT--VMELHNPLQRAIPCRIHCHPY-----------------------------NVGTLAGSTAGGQVYVWTTK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 516
67 -49.400[Z] KOG0313 Microtubule binding protein YTM1 (contains WD40 repeats)  ali follow..  13  40.LLKDKNEFHKHVEFLIKGQFLRMPLDK-EIEYVEKCTAPQPEQCMFHDDWISSIKGAEEW--ILTGSYDKTSRIWSL-EGKSIMTIVGHTDVVKDVAWVKKDSLLLSASMDQTILLWEWNVEKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDPIVTLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVGSGSLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKD-GSLVSLSLTSHTGWVTSVKWSPTHQQLISGSLDNIVDLAAHEDKVLSVDWTDTGL-LLSGGADNKLYSYRYSPTTS......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 419
68 -48.900[T] COG5170 Serine/threonine protein phosphatase 2A, regulatory subunit  ali follow..  14  26...ITEADIISAVEFDHTGDYLATGDKGGRVVLFERNHSKKGCEYKEIEEKINKIRWCKRTNHFLLSTNDKTIKLWKLYEKNLKVVANAHAYHINSISVNSDAETYISAD-DLRINLWNLSISDHSENMEELTEVITSAEFHPNCNHLMYSSSKGNIKLLDLRQSALKSFFSEIISSISDVKFSQNGRYILSRDYLTLKIWDVNEKAPVKTIPLHDDKFECTFSGDDKHVLSGSYSNNFGIYPTDSSLPGDRGQIVLQADKAAFRA-WRSQPQAAMGSASVGLDPDNLDYNKKILHASWHPFEDSVAIAATNN-LFVFS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 461
69 -48.600[YU] KOG2445 Nuclear pore complex component (sc Seh1)  ali follow..  14  4.FDSGHDDLVHDVVYDFYGRHVATCSSDQHIKVFKLDKDELSDSWRAHDSSIVAIDWASPGRIIASASYDKTVKLWEEDPDQKLCTLNDSKGSLYSVKFAPAGLKLACLGNDGILRLYDALEPSDLRSPANHLQSDFCLSWCPSRFEKLAVSALEQAIIYKDGKLHVAAKLPGHKSLIRSISWAPSIG------------------------------------RWYQLIATGCKDGRIRIFKITEKL----SPLASEESLTNSNMFDNSADVDMDAQGRSDSNTEHDDHNGEVWSVSWNLTGTILSSAGDDGKVRLWKATYSNE......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 338
70 -48.300[R] KOG4497 Uncharacterized conserved protein WDR8, contains WD repeats  ali follow..  3.FSEVFKLSSLLCKFSPDGKYLASCV-QYRLVVRDVNTLQILQLY-TCLDQIQHIEWSADSLFILCAMKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEHLRITVWSLCTKS-VSYIKYPKACLQGITFTRDGRYMALAERRDCVSIFVCSDWQLLRHFDTDTQDLTGIEWAPNGCVLAVWDTCEYKILLYSDGRLLSTYSAYEWSLSVAWSPSSQFLAVGSYDGKVRILNHVTWKMITEFGHPEKSPQLGLGCLSFPPPRAGAGPLPSSESKDRANPKMGIGMLAFSPDSYFLATRNDNNAVWVWDIQKLR-----------LFAVLEQLSPVRAFQWDPQQPRLAICTGGSRLYLWSPAGCMSVQEGDFAVLSLCWHLSGDSMALLSKDHFCLCFLETEAVVGTACRQLGGHT................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 460
71 -48.300[R] KOG2321 WD40 repeat protein  ali follow..  47LQDFEYPEASNRIKCTRDGKYAMAGVYKPHIKVFDFAEMSLKFERHTDAENVQFEILSDDWTKSVHLQTDRTVDFHSQGGIHYSTRIPKY---GRDLKYHYPNCDLYLAAAGDEVYRLNLEQGRFLNPLKSPTGGVNVIDINPMHQLLAFGTDAGSVEFWDPRDRSRVGILEDNSRSVTALKYRNDGLNVAIGLSDGTLLYDLRSSSPYMSDQGYSMPIKSLHALDGTARVLSADSKIIKIWEKDTGKPF-----SSIEPTVELNDVCPIEGTGLILTANEGSPMHASFLDNITEEMEENPDDYKFVTKKELLNLGLDHLVGTGVIRAYHGFFIDNNLYEKARLIANPFSYEEHRQKIVK---------------ERLEKQRASKIRSQNRPKVNAGLASRLSYQENKLRKKTGVTDGPSILEDERFKNVFTDKEFEVD--EDTLEYKQLHPSRSEARGLTAAEESEEEKEHTKGIKFSSDEESLSDMEEENETFDALVDRRKTEQQVSNEKTPQETIRSTPSGMEMTFKVEKKKKSKPVNRDEDSTSGKKKQVTQGRRSASKNV......................................................................................................................................................................................................................................................................................................................................................................................................................... 630
72 -48.100[A] KOG0647 mRNA export protein (contains WD40 repeats)  ali follow..  17  2............SFFNRSNTTSALGTSTAMANEKDLANDIVI--NSPAEDSISDIAFSPQQDFMFSASSDGKVRIWDVQNGVPQRAQHESSSPVLCTRWSNDGTKVASGGCDNALKLYDIASGQ-TQQIGMHSAPIKVLRFPSNTECIVTGSWDKTIKYWDMRQPQPVSTVMMPER-VYSMDNKQSLLVVATAERHAIINLANPTTIFKATTSPLKWQTRCVCYNEADGYAIGSVEGRCSIRYIDDGMQKKSGGSNGQSLVYPVNSIAFHPLYGTFVTAGGDGTFGYPTLQASIPVCSFNRNGSVFAYALSYDWHQGHMGNRPDYPNVIRLHATTDEEVKEKKKR..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 365
73 -47.800[R] KOG2444 WD40 repeat protein  ali follow..  14  4....EFDNPPLCMKSNKDGSRLVVGFVDGSIRFYDTQQHEEEFQEIQTKSSIRGVDLDEHKKRVYAVTKNRSLCVFDIDTGKRVRCIKCHRSVPTAICTLPKSQQLATADESGEVKTWNLDPNANIRKWQEQDEDINDLKVDVKSNLLATSS-DGTLGAYDLRKAKLKMRSELMHSEL--YSVCGTNRSVYVGGEDGVEVFNLNENLLERVESGFEMGVGIVELRSGLLGLTSQGSNRMRLLNVQPSKRLGYYHGDEKSDDDGIDAITISTDKSTVFTMISMSCTIPILRAQDAKSKKMRKTEGFFDGLVGPKNDSDSDDDDEPKSKKRRNDEDSDEEIDEEEQEEDDEEEEEDS........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 382
74 -46.900[R] KOG1310 WD40 repeat protein  ali follow..  16  45.ELEGHQGCVNALAWNSNGSLLISGSDDLRINIWNYSSRKLLHSITGHTANIFCTKFVPEDELVVSGAGDAEVRLFNTSRLSPSALYQCHTRRVKKLAVEPNPNVVWSASEDGTLRQHDFRESTALADPPKQTLSLKSCDISARPHLLLVGGSDAFARLYDRRMLPPLSERGRTNLHLTHVTFSPNGEVLLSYSGEHVYLMN-GAIDMKRRYVGHCNVGTDILGQRGEYIASGSDDGRWFIWEKQTGRLMKV----------------------------------LVGDESVLNCIQCHPFDSVVATSGIDNTIKIWSPTASVPSIVAGGSA................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 702
75 -46.800[D] KOG1036 Mitotic spindle checkpoint protein BUB3, WD repeat superfamily  ali follow..  12  12.LSNPPSDGISNLRFSNNSDHLLVSSWDKRVRLYDVSTNSLKGEF-LHGGAVLDCCFHDDFSGFSVGA-DYKVRRIVFNVGK-EDILGTHDKAVRCVLFCDVTGQVITGSWDKTVKCWDPRGASGPERTQTYLQPERVYSMSLVGHRLVVATAGRHVNIYDLRNMSEQRRESSLKYQTRCVRCYPNGTGYALSSVEGVAMEFFDLSRKSEAGRDIVYPVNSIFHPIYGTFATGGCDGFVNIWDGNNKK----RLYQYSKYPTSISALSFSRDGQLLAVASSYTFEE---------------------KSQEPEAIFVRSVNEIEVKPKPKVYP................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 350

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zhao Y, Hong DH, Pawlyk B, Yue G, Adamian M, Grynberg M, Godzik A., Li T. The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesis. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3965-70. Epub 2003 Mar 21.