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Query: [T] KOG0279 G protein beta subunit-like protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAEGLVLKGTMCAHTDMVTAIATPVDNSDVIVTSSRDKSIILWKLTKEDKSYGVAQRRMTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLATGESTRRFVGHTKDVLSVAFSTDNRQIVSASRDRTIKLWNTLGECKYTISEADGHKEWVSCVRFSPNTLVPTIVSASWDKTVKVWNLQNCKLRNTLAGHSGYLNTVAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLEAGSIIHSLCFSPNRYWLCAATENSIRIWDLESKSVVEDLKVDLKAEAEKTDGSTGIGNKTKVIYCTSLNWSADGNTLFSGYTDGVIRVWGIGRYLast
1 -95.100[T] KOG0279 G protein beta subunit-like protein  ali  100  1MAEGLVLKGTMCAHTDMVTAIATPVDNSDVIVTSSRDKSIILWKLTKEDKSYGVAQRRMTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLATGESTRRFVGHTKDVLSVAFSTDNRQIVSASRDRTIKLWNTLGECKYTISEADGHKEWVSCVRFSPNTLVPTIVSASWDKTVKVWNLQNCKLRNTLAGHSGYLNTVAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLEAGSIIHSLCFSPNRYWLCAATENSIRIWDLESKSVVEDLKVDLKAEAEKTDGSTGIGNKTKVIYCTSLNWSADGNTLFSGYTDGVIRVWGIGRY 326
2 -72.200[K] KOG0263 Transcription initiation factor TFIID, subunit TAF5 (also component of histone acetyltransferase SAGA)  ali follow..  24  311.SLPSVCMYTFHHTNNNMNCAEFSPDST-MIACGFQESYIRLWSIKADKVEDSDGSVRLLSHSGPVYGTTFSPDNKYLLSCSEDASARLWSVDTKTALVAYKGHTGPVWDVAFGPFGHYFATASHDQTAQLWSCDHI--YPLRVFAGHLSDVDCVTFHPNSAY--VLTGSSDKTCRLWDVHRGHSVRVFNGHTQPVTAVAIAPDGHTMASADSEGLIHLWDIGTGRRIKTMRGHGNIYSLSFSRESTVLVSGGDCTVRAWDVFKTNYNNPVSSSSVVTPFSAKTSQMVALYTKQTPIFNVSFTRRNLCLAISVS............ 643
3 -71.600[R] KOG0286 G-protein beta subunit  ali follow..  21  1MGEMEQLRQEAEQLKKQIADARKACADVTL---AELVSGLEVVGR-----VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGKVSRELSAHTGYLSCCRFLDDNN---IVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHSDINAICFFPNGEAICTGSDASCRLFDLRADQELICFSHEITSVAFSLSGRLLFALSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN.... 340
4 -70.000[D] KOG0642 Cell-cycle nuclear protein, contains WD-40 repeats  ali follow..  23  454.....NPKFTLRSHFDGIRALAFHPIEP-VLITASEDHTLKMWNLQKTAPADVEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDGLIQGWNTTNPNLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPSVFNDIKELGIPASVDLVSSDPS--HMVASFSKGYTSIFNMETQQRILTLENSSCQINRVISHPTLSISITAHEDRHIKFYDNNTGKLIHSMVAHEAVTSLAVDPNGLYLMSGSDCSIRLWNLESKTCIQEFTAH---------------RKKFEESIHDVAFHPSKCYIASAGADALAKVF..... 779
5 -68.000[S] KOG0295 WD40 repeat-containing protein  ali follow..  21  51.KKWTTVLRLQRKVNDLESKLQESQREI-NHGAPTRDKRQAADWIPR-----PPETQKLTGHRLPITRVIFHPLWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDF-GQTYDCLKSLKGHEHTVSSVTFLPTGDF--VLSASRDHTIKQWDISTGYCVYTFRGHNDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLRDHHAVECVEWAPDTALFSGSRDRSIKAWNINTGDVLFTLLAHVRGLAFHPKGKYLISIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVWECR.. 404
6 -67.500[S] KOG0271 Notchless-like WD40 repeat-containing protein  ali follow..  20  91VRPVTRCSASIPGHGEPVISAQFSPDGR-GLASGSGDQTMRIWDIE-----LELPLHTCKSHKSWVLCIAWSPDATKIASACKNGEICIWNAKTGEQIKTLKRHKQWITSLAWQPTCRLLASCGKDGNIFIWDTVQGT--VVRCLSGHTASVTCLRWGGEGL---IYSGSQDRTVKMWRADDGVMCRNMTGHAHWINTLALNTDYALRTSCFEPSKRCIKPDTVEECQKVAQTRQLVNQVVFSPDTRYIASASDKSVKLWCGRTGKYLASLRGHVYQVAWSADSRLLVSLPGHGDEVFTVDWSPEGTKVVSGGKDKVLKLWR.... 472
7 -67.100[A] KOG0285 Pleiotropic regulator 1  ali follow..  19  155.HAPWKNYRVLQGHLGWVRSVAFDPSN-EWFCTGSADRTIKIWDV-----ATGVLKLTLTGHIGQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKVIRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVWDIRTKMQIFVL---PHDSDVFSVLARPTDP--QVITGSHDSTIKFWDLRYGKSMATITNHKKTVRAMALHPKENDFVSASADNIKKFSLPKGEFCHNMLSLQDIINAVAVNEDGVMVTGGDKGGLWFWDWKSGHNFQRAE-----------TIVQPGSLESEAGIYAACYDQTGSRLVTCEGDKTIKMWKEDE. 457
8 -66.700[S] KOG0308 Conserved WD40 repeat-containing protein  ali follow..  17  16.ISFIIRDEHEYSNRSAVSALQYDAQNG-RLFTGGSDTIIRTWSVPHHKNSPVQYQGSLEQHTDWVNDMILCGHGKILISASNDTTVKVWNIERDNFIDCIRTHKDYVSCLAYAPIVEKAVSASFDHNIFVYDINAN-FKTVNNLIGCKDSIYSLATTPNLS--LVLGAGTEKCIRLFDPRTNEKIMKLRGHTDNVRALVVNDDGTRALSAGSDATIRLWDIGQQRCIATCIAHEGVWTLQVDSSFTTVYSAGDKMVVKTPLYDFTKSQLLFKEVKKLLLSEKDNPVSLVIPGAPAIKKHAMLSDKRHVLTRDSDGNVALYDVLA. 422
9 -66.600[JT] KOG0643 Translation initiation factor 3, subunit i (eIF-3i)/TGF-beta receptor-interacting protein (TRIP-1)  ali follow..  16  5.........LLQGHERSITQIKYNREG-DLLFTVAKDPIVNVWYSV-----NGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALL-KTNSAVRTCGFDFGGNIIMFSTDKQMVSFFDLRDDNNEPYMKIPCNDSKITSAVWGPLGE--CIIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGQEAMDVTTTSTRIGKFEAR-----FFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDP. 316
10 -66.200[D] KOG0267 Microtubule severing protein katanin p80 subunit B (contains WD40 repeats)  ali follow..  21  2.........SLCGHTSPVDSVAFNSEE-VLVLAGASSGVIKLWDLEE-----SKMVRAFTGHRSNCSAVEFHPFGEFLASGSSDTNLRVWDTRKKGCIQTYKGHTRGISTIEFSPDGRWVVSGGLDNVVKVWDLTAG--KLLHEFKCHEGPIRSLDFHPLEFL--LATGSADRTVKFWDLETFELIGTTRPEATGVRAIAFHPDGQTLFCGLDDG-LKVYSWEPVICRDGVDMGWSTLGDFCINEGKFIGCSYRNSVGIWVSDISELEDKNECMVKRFSVLNDQSERMGPDYETREIKNIYVDSTGGNLNVAQNPGSLKATLPLE. 322
11 -66.000[A] KOG0265 U5 snRNP-specific protein-like factor and related proteins  ali follow..  21  41TSNLQAPIMQLEGHEGEIFTAEFHPEG-ELLLSSGFDRQIYIWQVYED----CENVMAMSGHSGAVMEAHFTPDGSHIFTCSTDKTLAFWDIATGQRQRRFKGHGNFVNSVQGSRRGQQLCSGSDDRTIKIWDARKKHAAHT----ESPFQVTAVCFGDTGE--QVISGGIDNEVKIWDIRKQAVLHHLRGHSDTITGMSLSPEGDFILTNAMDNTLRVWDVRGERCVKVFQGHKNLLRCAWSPGSDKITSGSDRHVYIWDVNTRRILYKLP-------------------GHNGSVNAVDFSPKEPLILSGSSDKTLYLGEIDE. 347
12 -65.600[A] KOG0291 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  19  337.LPDVNMIHSLSISDYPISAALFNCTGDWVALASREIGQLLVWEWQS-----EQYIMKQQGHSSEMTCIAYSSDGQFIATGGEDSKVKLWNTQSSFCFVTFSEHTSGVTGIQFSRNKKFLVSSSLDGTVRAFDVNRYRNFR-TFTSPNPAQFSCVAVDYSGEL-VVAGGQDVFDIFLWSVKTGKLLEIISGHEGPVVSIAFSPTSSTLVSGSWDKTVKIWNCLESNSEHETIDASDVTNVTFSPSGEEIAVATSGNITIFDIKSAGQVTTIEGRNDLSGRLETDIITARKNAQANYFSTIEYSADGECILAAGKSANICIYHVRE. 658
13 -65.200[U] KOG0276 Vesicle coat complex COPI, beta` subunit  ali follow..  21  1MPLRLEIKRKLAQRSERVKSVDLHPTEP-WILASLYSGTLCIWNYQ-----TQVMAKSFEVTELPVRSAKFVARKQWVVAGADDMYIRVYNYNTMDKVKVFEAHSDYIRCVAVHPTLPYVLSSSDDMLIKLWDWEKG-WACTQIFEGHSHYVMQVTFNPKDT-NTFASASLDRTIKIWNLGSPDPNFTLDAHQKGVNCVDYFTGGDYLITGSDDHTAKVWDYQTKSCVQTLEGHHNVSAVCFHPELPIIITGSDGTVRIWHATTYRLENTLN-------------------YGLERVWAIGYIKSSRRVVIGYDEGTIMVKLGRE. 302
14 -65.100[B] KOG0273 Beta-transducin family (WD-40 repeat) protein  ali follow..  19  165VEIPPNKATVLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIWTE-NGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGE--AKQQFPFHSAPALDVDWQNNMT---FASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHKEIYTIKWSPTGPLASASFDSTVRLWDVEQGVCTHTLMKHVYSVAFSPDGKYLASGSFGTGGIFEVCWNARGDKVGASASDGSVCVLDL... 522
15 -64.300[R] KOG0645 WD40 repeat protein  ali follow..  20  1...........SGHTGRLWSVAAHPMLP-LFATSSQDKSVRIYNSNT-----YNLVHVIDGHTRSIRRVAWRPIERVLAVASFDSVVSINEKDDWECTAALEGHENEVKCIAWSCNGNYLATCSRDKSVWIWEATEDDEDCLAVLQEHTQDVKVVTWHPTEDL--LVSGSYDNSICFWRDDDWALTCQLQGHTNTVWALAFSPNGNTLASADNDGNVFLWIKISSNEDVATIDSGAVYTISWMNDATLCSAGGDGKIVVYQREKHD------------EALWHVAYEQDHAHGVYEINSLEYLRDDR-LLSGGDDGECRVWSFK.. 322
16 -64.000[S] KOG0282 mRNA splicing factor  ali follow..  23  277...PKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGE----RRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNR-KVPYCVKFNPDEDLFVAGMSDKKIVQWDIRSGE--IVQEYDRHLGAVNTIVFVDENR--RFVSTSDDKSLRVWEWDIPVDFKYIEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKVAGYACQVDFSPDMSYVISGDNGKLNIWDWKTTKLYSRFK-------------------AHDKVCIGAVWHPETSKVITCGWDGLIKLWD.... 579
17 -63.900[S] KOG0316 Conserved WD40 repeat-containing protein  ali follow..  19  7...PTKEAHILKGHEGAVLAARFNGDG-NYALTCGKDRTIRLWNPHR-----GILIKTYKSHGREVRDVHVTSDNAKFCSCGGDRQVYYWDVSTGRVIRKFRGHDGEVNAVKFNDSSSVVVSAGFDRSLRVWDCRSHS--VEPVQIIDTFLDTVMSVVLTKT--EIIGGSVDGTVRTFDMRIGREMSDNLGQP--VNCISISNDGNCVLAGCLDSTLRLLDRTTGELLQVYKGHISKTDCCLTNSDAHVIGGSDGLVFFWDLVDAKVLSKFRAH--------------------DLVNSIDVDFYLRKFFVAGDKRELPPEGRLY. 302
18 -63.500[S] KOG0296 Angio-associated migratory cell protein (contains WD40 repeats)  ali follow..  16  48.MVMDMSVQGFFEHKDSVFSVSINPVHSNLCASGGGDDLGYIWDIT-----TGEQICQLTGHKDSIVAIDWSFDGTYIATGGMDSQVRLWKSSTGFEFITAFETVDEIVWLSWHPKGLFLAAGCNDGSIWMWSLPSGK--VVQVMYGHTAPVNAGKFIPPGVGKRLATVDDSGTLIVWNPATGAPECRMSETAAGWTSFDCNAEGNVLFLGGSSGKVKVVNINSSHILASLEAQESVEAIALCTALPICACASDGTVALYDSASLKFRKSLEQAVIDCKFLPNGQLLGEYTGHQEPILCMAITPDGKRVVTGSDDTELLVFDCEH. 399
19 -63.200[S] KOG1407 WD40 repeat protein  ali follow..  16  6IPFKSLHSREYQGHKKKVHSVAWNSNGT-KLASGSVDQTARIWNIEPH-GHSKAKDLELKGHTDSVDQLCWDPKHSLVATASGDKSVRLWDARSGKCTQQV-ELSGENINITYKPDGTHVAVGNRDDELTILDVRKFKPL---HRRKFNYEVNEIAWNMPGD--FFFLTTGLGTVEVLSYPSLKPLDTLTAHTAGCYCIAIDPKGRYFAVGSADSLVSLWDISDMLCLRTFTKLEPVRTISFNYSGEYIASASDLFIDIANVQTGRTVHQIPCR--------------------AAMNSVEWNPKYNLLAYAGDDKNPKYNTDEG. 305
20 -62.900[B] KOG0639 Transducin-like enhancer of split protein (contains WD40 repeats)  ali follow..  16  429.VPTIPPNLAGIPGGKPAYSFHVTADG-QMQPVPFPPDALIGPGIPR-----HARQINTLNHGEVVCAVTISNPTRHVYTGG-KGCVKVWDISHPGNKSDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKV--CFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMSSNVEVLHVNKPDKLHLHESCVLSLKFAYCGKWFVSQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVI.. 769
21 -62.700[A] KOG0640 mRNA cleavage stimulating factor complex; subunit 1  ali follow..  16  93.EPHSYETAYVTSHKQACRAGAFSCDGS-LVATGSVDASIKILDVERMEQQGHPVIRTLYDHTDEVSYLEFHPKEHILASASRDGTVKLFDIAKPSVKKKVFTDCEPVLCLSFHPTGDYVAIGTEHNVLRVYDVATTQCVSAIPSQQHKAGVTCVKYSPTGKL--YATGSYDGDIKIWDGISGRCINTIAEAHGAICSLEFTRNGKYLLSSGMDSLVYLWELCTSRPIQTYTGAGTTEAVFNHTEDYVLFPDETTSLCSWNSRNGCRLT------------------LNSLGHNGPVRYITHSPNGPAFLTCSDDFRARFWYRRA. 421
22 -62.600[A] KOG0306 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  23  402.QPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAA--ADSIKIWNRSTLQC-------IRTMTCEYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKSVKQTRTLQLDEDVLCVSYSPNQKL--LAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDSVMYLQFVPKSHLFFTAGDHKIKQWDADKFEHIQTLE-------------------GHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTR. 706
23 -62.300[Z] KOG0318 WD40 repeat stress protein/actin interacting protein  ali follow..  22  9YENKNIYATLPRTQRGQPIVLGADPKGKNFLYTN--GNSVIIRNIEN-----PAIADVYTEHSCAVNVAKYSPSGFYIASGDASGKIRIWDTVNKEHLNEFQPIAGPIKDISWSPDNQRIVAVGEGRERFGHVFMSETGTSVGEISGQSKSINSADFRPARPF-RIVTGSEDNTIAVFEGPPFKFKMTKQDHSRFVQAVRYSPDGKFFASAGFDGKVFLYDGTSSELVGEFGHKGGVYALAWKPDSTQLLTCSDKTCRLWTVESRELVSEFTVDDQQVSCLWQGDNLITVKGHNKPITVLGLSDDRSTIYTGSHDGVVTNWNSGS. 356
24 -61.800[R] KOG0288 WD40 repeat protein TipD  ali follow..  23  217STIPSTCANRIHAHEGGCGSIVFEYNSG-TLFTGGQDRAVKMWDTN-----SGTLIKSLYGSLGNILDMAVTHDNKSVIAATSSNNLFVWDVSSGRVRHTLTGHTDKVCAVDVSKFSRHVVSAAYDRTIKLWDLHKGY---CTNTVLFTSNCNAICLSIDGL--TVFSGHMDGNLRLWDIQTGKLLSEVAGHSSAVTSVSLSRNGNRILTSGRDNVHNVFDTRTLEICGTLRASSNWSRSCISPDDDYVAAGSDGSVHVWSLSKGNIVSILK-------------------EQTSPILCCSWSGIGKPLASADKNGYVCTWT.... 515
25 -61.600[ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA cleavage factor II complex, subunit SWD2  ali follow..  18  9VVRSFKVAKIFRENTDKINAIDFAPNG-EHLISCSEDDQIVIYDCEK-----GTQSRTVNSKKYGVDLIHFTHANNTASSTKVDDTIRYLSLHDNKYLRYFPGHTKKVISLCISPVEDTFLSGSLDKTLRLWDLRSPNCQGL-----HLSGRPIAAYDPEGL--IFAAGVNSESIKLYDLRSFDTFKLNQEKECDWTGLKFSRDGKTILISTNGSVIRLVDAFHGTPLQTFTGYGIPIEASFSPDSQFIFSGSDGRVHIWNADTGNKVSVLNGD------------------HPGPVQCVQFNPKYMMLASACTNMAFWLPTSEE. 315
26 -61.500[R] KOG0315 G-protein beta subunit-like protein (contains WD40 repeats)  ali follow..  17  23AHTGNCIKTMRFVETSQVNALDRTPDKTRLAACG--YQCIRLYDLESNC---TAPVINFDGVQKNVTRLGFQEDGNWMFTAGEDHHVRIWDMIAAPHCSRIFDCEAPVNAACLHPNQVEIAMGSQNGSVFLWDVKSER--HERIVPEVDASIQDVAISPDGRY--LAAANNKGNCYIWSLTSQRPNRKIPAHSRYILRCKFSPDSRLLLTTSGDGTVCIWKTDDFSKWRELCIENWVWDAAFSADSKWLFTASDGIARLWKLQTKSSIRDYTGHITALSFKDEIPVKSTRDNPPGTNNLAFFETVGRVAMNPYMGNTTTELN.... 362
27 -61.500[Z] KOG1523 Actin-related protein Arp2/3 complex, subunit ARPC1/p41-ARC  ali follow..  13  1.......MSLHQFLLEPITCHAWNRDRT-QIALSPNNHEVHIYKKNGSQ----VKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQKDGKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFEAENDVSKHIKKPIRSTVLSLDWHPNNV--LLAAGSCDFKCRVFSAYIKEVEFGGSGTGGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLKTEFPLLSVSFVSENSVVAAGHDCCPMLFIYDDRGCLTFVSKLKQSIQRNMSAMERALETLHQNSITQVSIKQDCRKFCTTGIDGAMTIWDFKT. 359
28 -61.100[R] KOG0289 mRNA splicing factor  ali follow..  18  208.RQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSS-----EQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLI--FGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQNNFEVKSLIFDQSGTYLALGGTD-VQIYICKQWTEILHFT-------------------EHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL... 504
29 -60.900[A] KOG0319 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  20  263.IETAKLVRKKRIASSNLDHLAYDVVSNR-FLAISAEQNLIILDFEN-----LKIARQIVGHDEIYSCCLLGKDESHMAVASNTSEIRLYNTKTLDCQLIRGHTESVLSVVSPTWDTSLLASCSKDNSIIFWRLVTSTLVPVAAATGHANTVTALAISNTGRAPFLASVSTDCTIKLWGLGKLTCSSTMVAHGKDVNCVDISESDALIATGGMDKLVKLWQVDTHKMAGTLSGHRGVGDVKFAKNSHKLASCSDMTIKIWNISEKSCLQTISGHVFRVIFARNDSQLISIDAHTDKIWSLSKNHNESEFVTAGTDGRIVVWKDVT. 638
30 -60.200[S] KOG0772 Uncharacterized conserved protein, contains WD40 repeat  ali follow..  20  110.LIPAACEAKISHGTQAISALRVEPPGVR-FASGGLDYYVKLFDFQKMDMSMRYDKELLPAESHVINSLAFSPNGETLVVASGEAIIRLLDRAGKQWLNITKGHTATVNCVEFNPLNKEFISCSDDGSLRLWNLDDHKVITTKGANGKRVSPQVCTFSPDGKW--IAAGCDDGSVQAWKYGSQYVYLVRKAHNGSITSIAFSPDSKRLLSRGFDDTLKMWSLDNPKEPLLVENAFKSTDCGFSPRAEVVFTGTPGTLQFFDPMTFDLVYKID-------------------YPGISCHRIQWHPRLNQIIAGLSDGTIHVYYDQT. 449
31 -59.900[S] KOG0293 WD40 repeat-containing protein  ali follow..  18  263...PSQTAQILESHTDEVWFLQFSHNGK-YLASSSKDQTAIIWEISADGHI--SLKHTLVGHHKPVIAILWSPDDRQVLTCGAEEVIRRWDVDSGDCVHMYEKGGISPISCGWYPDGQGIIAGMTDRSICMWDLDGRE--KECWKGQRTQKVSDIAMTDDGKW--LVSVCKDSVISLFDREATV--ERLIEEEDMITSFSLSNDNKYILVNLLNQEIRLWNIEGDPKIVSRRSRFIIRSCFGGYKQAFIASGSDSQVYIWHRSTGKLIVELP-------------------GHAGAVNCVSWSPTNLMLASASDDGTIRIWGLDR. 563
32 -59.800[R] KOG4227 WD40 repeat protein  ali follow..  15  40.GCRNLYKKDLLGHFGCVNAIEFSNNGGQWLVSGGDDRRVLLWHMEQAIHSRVKPIQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVILHDVESSETLDVF-AHEDAVYGLSVSPVNNIFASSSDDGRVLIWDIRESPHGEPFCLANYPSAFHSVMFNPVEP-RLLATANSKEGVGLWDIRKPQLRYGGNLSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHSRLPVFQFDNSCTMKSCCFAGDRDILSGSDDFNLYMWRIPADPEAGGIGRVV--------NGAFMVLKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSPYK. 364
33 -59.300[A] KOG1272 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  16  65LASREKLYGKSAKAAAKIEKWLLPAEAG-YLETEGLEKTWRVKQANEVDILSSRNQYDIVLPDFGPYKLDFTASGRHMLAGGRKGHLALLDMMNMSLIKEI-QVRETVRDVAFLHNDQFFAAAQKKYAYIYGRDGTE-----LHCLKERGPVARLRFLKNHFL--LASVNMSGQLHYQDVTHGGMVASIRTGKGRTDVMEVNPYNSVVGLGHSGGTVTMWKPTSQAPLVQMQCHGPVSSVAFHPNGHLMATSGERKIKIWDLRKFEEVQTIHSFAKTLSFSQKGLLAAGSMVKGYQIEKVMFRPYEDVIGIGHSMGWSSILIPGS. 411
34 -59.300[S] KOG0321 WD40 repeat-containing protein L2DTL  ali follow..  19  121........ECLMMLNQLPFCLGFANNES-LLAVCTETGALELFDSRFYDQPSARRIHGWLAHNNAIFSVNFSKDDSLLATSSGDQTSKVFDLSTQQCITRLGYHSHSVKQVNFCNDSPNLVSCSRDGSIIFWDMRTHGITIAHENSGRDCSITSATWLPQSTSQVISSCSANSALKLWDLRTVHTVRTTSKRDFGVTNVCTSPDGERIYAASRDSIIYEYSSRHLNS-PRLRISSFYVKLACSPDGATLACGGTSGVVVFDTTRNC-----------------SSSAMLTGGHTKDVTAVDWSSEGQ-LASISDDGSVRVWNSSL. 467
35 -59.000[A] KOG0272 U4/U6 small nuclear ribonucleoprotein Prp4 (contains WD40 repeats)  ali follow..  22  248.LQSLAPLCSQVGDTRPVSSAAFSEDSS-LLLTSSWSGLCKLWSVPD-----CELKQTLRGHASYVGGVALRPGVKAMASGGHDGAVKLWGFNNEESIADITGHMPHVSKVAFHPSGRFLATACYDSSWRLWDLEQKT--EVLHQEGHAKPVHCLSYHSDGSV--LVTGGLDAFGRVWDLRTGRCIMFLEGHLGAVFGVDFSPNGFHIATGSQDNTCKIWDLRRRQPVYTIPAHNLISDVKYQQEGSFLVTCSDSTTKIWSNKTWQPLKTLQ-------------------GHDNKVISVDIAPNSQYIATTSFDRTFKLWSPDS. 553
36 -58.100[R] KOG2096 WD40 repeat protein  ali follow..  17  78......DLNTLKGHGDAVTGLCFSSDGK-SLATACADGVIRVFKLDDASSLKFRFLRINLPAGGHPTAVAFADDASSIVVGKLPLPSIKWDHHHIHEKRSVLTISGATATYGTADGSVVIASCSEGTDIVLWHGKTGR--NLGHVDTNQLKNHMAAVSPNGRF--LAAAAFTADVKVWEIVYQKRVMQLKGHKSAVTWLCFSPNSEQIITASKDGSIRVWNINVRYHLDE-GNPLHYDRLSLCPEGKILAASHGSTLQWLCAETGNVLDTA------------------EKAHEGDITCISWAPKAMVLGTSGDDKKVKLWEAPK. 450
37 -57.900[A] KOG0299 U3 snoRNP-associated protein (contains WD40 repeats)  ali follow..  16  128.DVKIETAQLRGRHMRPLVGVVAYENF---VYSADKSGLIQKWEALQEKIKFSRSRRGENDHVKEITCLAISNDGRWIVTGGLDHRIVIRDSVTLEPQHCWKHHRDAVMGLAMRRGTNEMFSCSADRSIKVWSLDQMS--YIETLFGHQDVIFGVDALARERC--VSVGGRDRTSRLWKIVEESQLKATAGYMEGSVDCVAMIDEDHFVTGSDNGVIALWSVQRKKPLFTYPLARWITSLAAIPYSNLFASGSDGNIRLWKIAEGLRSFEPLTIATPL-------------SVYGCINSLSLSLQGKVFAACGRETRVGRWKTLR. 497
38 -57.900[I] KOG0301 Phospholipase A2-activating protein (contains WD40 repeats)  ali follow..  16  16.MPQYTISHVIEAHKSDTKALAVTQGGC--LISGGRDETVKFWAKKGKQYT--KTHAFEQPKGITVNSIAYAEDGWRLFVGRRDGTIAVFGPSQAEPYAIFNEHKQNVCCLHINEKATHMLSGSWDSNVIIWPITESSSFTTIVCPGHTLSVWALASFPDLP-NTYLSASADKTIRMWF--GDTTLSVFKGHTDVVRALVVLSSSH-FLSAGNDGHIIHWDVASASILRKFATQAHEFIYSMTLSDSHILTTGDGTLEFWAIDGGKDGNL------------AIVSEAVIQLPTTNTWDAKVLLNSD-IAVAGSDGRIYIMTTDK. 323
39 -57.800[S] KOG1409 Uncharacterized conserved protein, contains WD40 repeats and FYVE domains  ali follow..  13  18.GAKPALLHRITGHVARINDVILLSKD-EGVWTASDDRSVRLYLKRDNDFNSMTESRKWTCHAGPISGLGFALSSELIFSCSRDKSIVWHCSENSN---KMGSYLLENSCTAMVIDLPFVFVGDHGGHVTVLRIVDNQPNLVSKLSAHTNAITSLTWDGNKKV--LYSGSSDHLIIMWDIGGGREAYELNGHNGKVTTLCAAPAAKRLFSADEHGKLMCWDMNCKRVETPEWKTGSAVCGSCCDNWTTYPPGYETKIRICNDCNARMKDNPQ--------NFNLTPLAIPHEIHTGITAMHLQETLGLLVTSGQNRVIMIWDVRS. 406
40 -57.700[R] KOG2394 WD40 protein DMR-N9  ali follow..  17  230........GSVNNRQDRCTSISWVPGGDGAFVVAHADGNLYNKDGATESYSKSNPVARWHICQGSINSIAFSNDGAHLATVGRDGYLRIFDFLTQKLVCGGKSYYGALLCCSWSMDGKYILTGGEDDLVQVWSMEDR--KVVAWGEGHNSWVSGVAFDSNWSSPNFGSVGQDTQLLLWDLEMDEIVVPLRRAPGGSPTYSTGSSAHWDNVGTLQPAPCKRDVPKLSPIIAHRVHEPLSGLMFTQES-VVTACREGHIKIWTRPSESETQTNS----------------SEANPTTALLSTSFTKDNKASLSSKIISGSTFKQ.... 556
41 -57.600[J] KOG0650 WD40 repeat nucleolar protein Bop1, involved in ribosome biogenesis  ali follow..  14  384LREVPAYSRYLRERFLRCLDLYLCPRAKR-VKLNIDAEYLIPKLPSPRDLQPTVESMVYRGHTDLVRSVSVEPKGEYLVSGSDDKTVKIWEIATGRCIRTVITHFKPIRQVTWHGRGDYLATVMPEGANRSALIQLSKRRSQIPFSKSKGLIQFVLFHPVKPCFFVAT---QHNIRIYDLVKQELVKKLLTNSKWISGMSIHPKGDNLLVSTYDKKMLWFDLDSTKPYQTMRLHNAVRSVAFHLRYPLFASGSDQAVIVSHGMVYNDLLQ----------NPLIVPLKKLQTHEKRVLDVNWHPVQPWVFSTGADSTIRLYT.... 784
42 -57.600[S] KOG0283 WD40 repeat-containing protein  ali follow..  15  342.GVAHSMSLRVADKDVSDGSTDSPKKGK-DHKHGKANEWVKVRPTGKSELSALHMCQEIQAHEGAVWTIKFSQDAHYLASGGADRVIHVWEVQECELMSMNEGSLTPIHPSLCDSSGNEITVVEKKKKGKGSSGRRHSDKPVCSLKGHLDAILDLSWSKSQL---LLSSSMDKTVRLWDIETKTCL-KLFAHNDYVTCIQFSPDENYFLSGSLDAKIRIWSIQDRHVVEWSDLHEMVTAACYTPDGQGALIGSKGICRAYDTEDCKLSQTNQIDITSFQFSPVNPSEVLVTSNTCSQLSASYSQDGKYIICASEDSQVYLWKNDF. 713
43 -57.300[BK] KOG1063 RNA polymerase II elongator complex, subunit ELP2, WD repeat superfamily  ali follow..  16  291.TYQISVESVLIGHEDWVYSVEWQPPVIDSILSASMDKTMMIWRPEKKTGVNVVCVGELSHCALGFYGGHWSPNSLSILAHGYGGAFHLWRNVSSQMQKVPSGHFAAVTDVTWARTGEYLLSVSQDQTTRVFSAWKNDELARPQVHGHDINCVAMVQGKGNH--RFVSGAEEKVVRVFEAPLSPESHKLYGHGNELFSLCSDHKGNLVASSCKAQSIWLWEVGTWKAVGRLQSHSTVTHLEFSYDDTLLLSVSDRHFSVFSIQRTD------------NGEVSHKLMAKVEAHKRIIWACSWNPFGHQFATSSRDKTVKIWSVEN. 727
44 -57.000[T] KOG4378 Nuclear protein COP1  ali follow..  17  30.SGDPCVLSYTPSPGCAVNSVKWNHTNL-VVASTGEDKKISLWRKNGQSLGT-TGKDGGDSAEECLSAISFSKKGRYICSGGTGQIVKIWDLQRKLCIKKLKGHTSTITGVMYNCKDEHLASVSVGGDLIVHNLASGARATEGQVVQFVHVLRLLDYSRSSR-HLLVTAGDDGTVHLWDTTGRSPKMSLKQHSAPTAGVCFSPSNEIIASVGMDKKLYTYDSGSRRSSSCIAYEAPFSSLAFGDNGYILVAGTNGRVVFYDIRGKPQPVTV----------------LHAFSNSEDVTSLSWQTSKPVIVNEKNYTSEMALLGST. 346
45 -57.000[U] KOG0277 Peroxisomal targeting signal type 2 receptor  ali follow..  18  3.AVCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQGTLLILDPDEA----GLRLFRSFDWNDGLFDVTWSENNEVLITCSGDGSLQLWDTAKAGPLQVYKEHAQEVYSVDWSQTRGLVVSGSWDQTVKLWDPTVGK--SLCTFRGHESIIYSTIWSPHIP-GCFASASGDQTLRIWDVKAAGVRIVIPAHQAEILSCDWCKNENLLVTGAVDCSLRGWDLRNRQPVFELLGHTAIRRVKFSPHASVLASCSDFTVRFWNFSKPD------------------SLLETVEHHTEFTCGLDFSLQSPQVADCSWDETIKIYDPAC. 318
46 -56.900[A] KOG0268 Sof1-like rRNA processing protein (contains WD40 repeats)  ali follow..  13  53.VFAKPFLASLDGHRDGVNCLAKHPEKLATVLSGACDGEVRIWNLTQ-----RNCIRTIQAHEGFVRGICTRFCGTSFFTVGDDKTVKQWDEQRTNPICSMTWGFDSISSVKFNPIETLLGSCASDRNIVLYDMRQATPL---KKVILDMRTNTICWNPMEAF-IFTAANEDYNLYTFDMRADTPVMVHMDHVSAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSREVYKRMQHVICVKWTSDSKYIMCGSEMNIRLWKANASEKLGVLTSRKEKFQHYPHIKRIAREARRRKEVNRIKHSKPGSVPLVSEKKKHV-VAVVK.. 445
47 -56.700[S] KOG0281 Beta-TrCP (transducin repeats containing)/Slimb proteins  ali follow..  26  190.RCGRHNLQRIQCRSENSKGVCLQYDD-EKIISGLRDNSIKIWDKT-----SLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGL--MVTCSKDRSIAVWDMASATDTLRRVLVGHRAAVNVVDFDDK----YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQY--RDRLVVSGSSDNTIRLWDIECGACLRVLEGHELVRCIRFDNK-RIVSGAYDGKIKVWDLQAALDPRAPA----------STLCLRTLVEHSGRVFRLQF--DEFQIISSSHDDTILIWDFLN. 487
48 -56.200[R] KOG1539 WD repeat protein  ali follow..  19  217IKLDEEIVTFEHASRGAVTALSFSTDGRPLLASGGSFGVISIWNLNKKRLQS----VIRDAHDSSIISLNFLANEPVLMSASADNSLKMWIFDTNRLLRFRSGHSAPPLCIRFYSNGRHILSAGQDRAFRLFSVIQEQKGVFVSRNHLLLAILACAISACGNF--AVVGTAGGWIERFNLQSGISRGSYYAHDGEVIGVACDSTNTLMISAGYHGDLKVWDFKKRELKSQWDVGCSLVKIVYHRVNGLLATVADFVIRLYDVVTLKMVREFR-------------------GHTDRITDLCFSEDGKWVISSSMDGSLRIWDVIL. 609
49 -56.100[R] KOG1524 WD40 repeat-containing protein CHE-2  ali follow..  17  2..KLKLSASRKTRHTEMVCGVGWIGTEA--ILSAADDHVFLLTNTAT-----NESQQILNMPETFFRSQTKGGQNDVFAVSTSDGKINILS-RNGKVENMVDAHNGAALCARWNSDGTGLLSSGEDGFVKMWSRSGM---LRSVLAQFATAVYCVAWDSTSS--NVLYCNADHCY-IKSLKMQVAPIKWKAHDGIILCCDWNPTSDLIVTGGEDLKFKVWDGFGQILFNSSVHDYPITSISWNTDGTLFAVGSHNILRLCD--------------------KSGWSHSLEKMNAGSVMALSWSPDGTQLAVGTAAGLVFHAHIID. 298
50 -55.500[S] KOG0310 Conserved WD40 repeat-containing protein  ali follow..  16  13.SRKQETILLDEDEPAVVSSVRISPKKP-YHVATTSSVRLTLYDT-----VVCEPLNLFSRFKKGVCSIDFRHDGRLLAIGGDEGKVRIFDVESKVALRVMQASQSTVKSVHFSPRGDTVFSMADDGKIKQYRVADTNAVPIIEIQAHEDAIRCGAVSSIND-HIVLTGGYDHKVRLWDIRSKEKSLEL-DCEHPVESVLFLPGEQLIATAA-GPIVKIWDTTTGRQLTALQAHKTVTSLRLATNSTCLLSAGDRRVNAFRTTNYSLINSWS--------------------MPSPVLDIDVSRDDQTMAIGMGNLLALYRRAEI. 318
51 -55.400[YU] KOG2445 Nuclear pore complex component (sc Seh1)  ali follow..  17  1......MQPFDSGHDDLVHDVVYDFYGRH-VATCSSDQHIKVFKLDK-DTSNWELSDSWRAHDSSIVAIDWASPGRIIASASYDKTVKLWEEDPDQKLCTLNDSKGSLYSVKFAPAGLKLACLGNDGILRLYDALEPSKVLSIPPANHLQSDFCLSWCPSRFSPEKLAVSALEQAIIYKDGKLHVAAKLPGHKSLIRSISWAPSYQLIATGCKDGRIRIFKITEKLSPLASEESTNSNMFDNSADVDMDAQGRSDSAELQSNLQVELLSEHD-------------------DHNGEVWSVSWNLTGTILSSAGDDGKVRLWKATY. 335
52 -55.300[A] KOG0284 Polyadenylation factor I complex, subunit PFS2  ali follow..  18  120.ILTKFIRTAMNKVKCPVYSVCWSPEGKR-LITGCQTGEFTLWNGTA-----FNFETILQAHDSAIRALKWASNEQWLLSADQGGYVKYWQPNMNNAHMFSAHKDEAIRGLAFAPTDVKFATASDDGTARVWDFARYT--EERVLRGHGAEVRCIDWHPTKGLIATGSRDTQQPVKIWDPKSGSCLATLQEHKSSVMAVEFNKNGNWLLTGGRDHLVKMYDIRMMKEMRTYRAHKEVISLAWHPIHEGLSGGGDGSIVYWMVDGEKEIGLL------------------EHAHDQAIWSMKWHPLGHILATGSNDNNTKFWARNR. 420
53 -54.200[R] KOG1334 WD40 repeat protein  ali follow..  13  263FVQRFRLQYLLGSHAGSVSTIHFNQRG-TRLASSGDDLRVIVWDWVRQKP----VLNFESGHDINVIQAKFFPNDSTLAMCGHDGQVRVAELINAENTKRVAKHRGPAHELALEPDSYKFLTSGEDAVVFTIDLRQDRPVVVTRENDKKVGLYTISMNPANIY-QFAVGGHDQFVRIYDQRRIDKKENYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQYVKRYKIKCVNFYGPRSEFVVSGSCGHVFFWEKSSSQIIQFMEGD------------------RGDIVNCLEPHPYLPVLATSGLDQHVRIWTPTA. 593
54 -54.100[R] KOG0646 WD40 repeat protein  ali follow..  18  20.LKTGTEQLQFKPCASPAHGLTAVGEKSSQLSARNTSGSIFYWSWTKPQ------AEVKSYPVEPIKALAANNEGTYLVGGGISGDIYLWEVATGKLLKKWHGHYRSVTCLVFSGDDSLLVSGSQDGSIRVWSLIRGNTLYEHNFNEHTMSVTDIVIDYGGCNAVIISSSEDRTCKVWSLSRGKLLKNI-IFPSVINALALDPGGCVFYAGARDSKIYIGAINATSEYGT-EKGKAITCLAYCADGNLLISGSDGVVCVWDPKSLRHVRTLIHAKGSRK-SRGALIPPPLEKYER---PVEDTMDGIVTVDPPPFSDVPVYSSFL. 376
55 -54.000[DO] KOG0305 Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits  ali follow..  19  112QNSERVLDAPGLRDDFSLNLLDWGSAN---VLAIALGDTVYLWDASSGSTS---ELVTIDEDKGPVTSINWTQDGLDLAVGLDNSEVQLWDCVSNRQVRTLRGGHE-SRVGSLAWDNHILTTGGMDGKIVNNDVRIR-SSIVETYLGHTEEVCGLKWSESGN--KQASGGNDNVVHIWDRSLAQWLHRFEEHTAAVRALAWCPFQASLLAGVGDGKIKFWNTHTGACLNSVETGSQVCSLLWSQSERELLSSTQNQLTLWKYPSMSKMAELN-------------------GHTSRVLFMAQSPNGCTVASAAGDENLRLWNVFG. 419
56 -53.700[U] KOG1332 Vesicle coat complex COPII, subunit SEC13  ali follow..  17  5......INTVDTSHEDMIHDAQMDYYGT-RLATCSSDRSVKIFDVRNGGQ---ILIADLRGHEGPVWQVAWAHPGNILASCSYDRKVIIWREENGEKSHEHAGHDSSVNSVCWAPHGLILACGSSDGAISLLTYTGEGQEVKKINNAHTIGCNAVSWAPAVV-KRFASGGCDNLIKLWKEEEDKEEQKLEAHSDWVRDVAWAPSTSTIASCSQDGRVFIWTCDDASSNTWSKFNDVVWHVSWSITANILAVSGDNKVTLWKESVDG----------------QWVCISDVNKGQGSVSSVTEGQQNEQ.................. 322
57 -53.700[S] KOG4328 WD40 protein  ali follow..  13  201.LLTLEPQNVARVVPGRIFVVQFLPCENKMVAAGDKLGNVGFWNLDCGNEEDNDGIYLFTPHSAPVSSIVFQQNSSRVISSSYDGLIRLMDVEKSV-FDLVYSTDEAIFSLSQRPNDQSLYFGQDYGVFNVWDLRAGK--SVFHWELHERRINSIDFNPQNP-HVMATSSTDGTACLWDLRSMGAKKSTVNHSRAVHSAYFSPSGLSLATTSLDNYIGVLSGANFENTCMIYHNNSKFKAVWGWDDSYIYVGNSKKIDVINPKLKRTVMELHNP-----------------LQRAIPCRIHCHPNVGTLAGSTAGGQVYVWTTK.. 516
58 -53.500[BL] KOG1009 Chromatin assembly complex 1 subunit B/CAC2 (contains WD40 repeats)  ali follow..  18  7........EIAWHNKEPVYSLDFQHGTAGRLASAGVDTNVRIWKVEPDGKAIVEFLSNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKVNDNTVVKTLRGHLEDVYDICWATDGNLMASASVDNTAIIWDVSKGQ--KISIFNEHKSYVQGVTWDPLGQY--VATLSCDRVLRVYSIQKKRVAFNVSSMKSFFRRLSFTPDGSLLLTPAGCVESGENVMNTTYVFSRKNPGKATLAVRCCPYRLVFAVASEDSVLLYDTQQSFPFGYVS------------------NIHYHTLSDISWSSDGAFLAISSTDGYCSFVTFEK. 377
59 -52.900[R] KOG2055 WD40 repeat protein  ali follow..  15  210.......ANFQAPSHSGIRCMSIHPYFP-LLLTCGFDRTLRIYQL---DGKVNPLVTSLHLRSSALQTALFHPDGKRVIAAGRRKYMYIWDLESAQVQKVQENFQPSMERFHVDPTGKYIALEGRSGHINLLHALTGQ---FATSFKIEGVLSDVLFTSDGS--EMLVLSYGAEVWHFNVEQRSVVRRWQVQDGSTTHFCLDPSNKYLAIGSKSGIVNIYDLQTSNADAA-NITFSINSMSFSQDSQVLAIASKDTLRLVHVPSFSVFRNWP----------------TSATPLGRVTCLAFGKGGE-LCVGNEAGRVGLWKLAHY 518
60 -52.800[R] COG2319 FOG: WD40 repeat  ali follow..  12  178.LPFRILDAPELRDDFYTSLLSWSPKGD---LAIGLAENIYLWSKELGP------TRVLEESIYDVSSVAYSYNGDILAVGRVDGTLQFWQDNERV-PRISIHHPGDIGVLAWKPETNRLLVGKGNGNIFVYDIISKAVLVATITNAHDEQVCGLTWNHDGSQ--FASGGNDNRVCLFKGSDLRQPLYVWQQNAAVKALSFCPWQRSLLAGSHDKHIRFYNCFNGKKIDELYCGAQITSIHWSPKYREFSVTVQHRFAVYSWPQLECLVSVLPS-----------------VPDIRCVHSVLTSQTDSIIIASSNETIKFFDLSE. 499
61 -52.600[S] KOG0294 WD40 repeat-containing protein  ali follow..  15  2........................PPEME-IIEATNEELLLGFKLIKSDSVKFELKQTFADSSYARSITSLAVQWPWVASGGTDGRIFVYDMRTRKQSQIILSHAGRVNTLKFTPDLSLLLSGSDDGHMIATRVGSWTKEYDWQKAHAGQAVTHVSCHPSSKL--ALSLGGDQVLNTWNLVNGCVAHKTNTLDFQTGCLSWSKQGDHFTLSG-PLVLEIWGIENAHVMRRIEMPSKPICITWLDGNECLTGLDNGNIAWISLKDEDDTP-----------------PTFILAHEVRVKAIAYL--NEFLATVSIAGQIKVWKIDM. 290
62 -52.200[Z] KOG0313 Microtubule binding protein YTM1 (contains WD40 repeats)  ali follow..  24  88.KCTAPQPEQCMFHDDWISSIKGAEEW---ILTGSYDKTSRIWSLE------GKSIMTIVGHTDVVKDVAWVKKDSLLLSASMDQTILLWEWNVEKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTTRTPIVTLSGHMEAVSSVLWSDAEE---ICSASWDHTIRVWDVGSGSLKSTL-TGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSSHTGWVTSVKWSPTHELISGSLDNIVKLWDTRSCK------------------APLYDLAAHEDKVLSVDWTDTGL-LLSGGADNKLYSYRYSP. 416
63 -51.800[R] KOG1273 WD40 repeat protein  ali follow..  13  18.........EEYLEHGVIKCVAFNHRG-SLLAAGCADGGCVIWDFE-----TRGIAKEIRDNSAAITSVSWSKYGHRLLVSAADKSLTLWDVSTGEKIARTIPLSSAPMIVDFDIDCTTLLPVSVPEMPDVLAPPQRS---KCPESNPPFSPAAACFNKCGDL--VYIGNSKGEILIVDYKSVRVLALVSSGAAPVKNIVFSRNGQYLLTNSHDRTIRIYENLLPAKNKMKTVGSHWKAPCFSGDGEWVVGGSEHKIYIWDR--------------------AGHLVKILEGPKEALIDLAWHPVHPIIVSVSLAGLVYIWAKDY. 348
64 -51.400[U] KOG0771 Prolactin regulatory element-binding protein/Protein transport protein SEC12p  ali follow..  14  1MASNQQPPSNLQTYGVPIYAVDWILEEA-VRSKITKDQDDDDDDGSSSSSLSEQPIGRRVIGTDLPYRMAIHPRQGGLICALPENIIEDDNEEESEKVVKELKDVGQQLSLSFNQDGTVLATGAEDGTLRVFEWPSMK--TLLNESKTHASVKSLTFSESGK---FLVSLGAPLCRVWDVNASAAIASLSKEKDEFASCRFSVDNSVAANTQRGGSIITWDTTSWRRRSSIKRNNSISAFNVSADGKLLAVGTEGDVLIIDSTKMQTNQIVK------------------KAHLGLVTALTFSPDSRCLVSVSFDSRARLTVIKQ. 349
65 -51.400[DK] KOG0973 Histone transcription regulator HIRA, WD repeat superfamily  ali follow..  16  2.........TFVGHDTSILAIDCHPSGKKFITCGTSNGLVVVWNAKKASNENVPKLLFQVESQSQSNSCRWSPDGKRFAFGSDDSSVSVWEYVGLKECCVLRGHSMEVLTVEWSPNGKYLASGSIDYRIIIYNARKL-PDRITVLNDIQLPVKGLSWDPIGKY--LASLEGDKKLRFWATDSWQCVKSVTIEETMLTRLDWSPDGKYLMTPAAVRLIKLIQRQTWKSDQFLAGHHGTTCVRAMPRTCAAVGSRDKSISIWVFPGTLKPLFVINNIFN-------------------HTVMDFAWCGRNLLACSQDGTVKVIHLSE. 348
66 -51.300[D] KOG1036 Mitotic spindle checkpoint protein BUB3, WD repeat superfamily  ali follow..  14  4.VTPSAGRELSNPPSDGISNLRFSNNS-DHLLVSSWDKRVRLYDVSTNS------LKGEFLHGGAVLDCCFHDDFSGFSVGA-DYKVRRIVFNVGKEDIFDFSILFFYTLCLFCDVTGQVITGSWDKTVKCWDPRGASGPERTQVGTYLQPERVYSMSLVGH--RLVVATAGRHVNIYDLRNMSEQRRESSLKYQTRCVRCYPNGTGYALSSVEGRVAMEFFDLSEAAQAKDIVYPVNSIAFHPIYGTFATGGDGFVNIWDGNNKKRLYQYS-------------------KYPTSISALSFSRDGQLLAVASSYTAIFVRSVNE. 339
67 -51.300[S] KOG2106 Uncharacterized conserved protein, contains HELP and WD40 domains  ali follow..  14  349.GTNRISYAVQGAHEGGISPLCMLRDGT-LVSGGGKDRKLISWSGNYQKLRSGDFTPITQGHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGHRPVWD-KIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKD--LVTVHTDGNEQLSVMRYSPDGNF--LAIGSHDNCIYIYGVSDNTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETGTDINAVCRAHEKKLLSTGDFGKVHLFSYPCSQFRAPSH----------------IYGGHSSHVTNVDFLCEDSHLISGGKDTSIMQWRV... 716
68 -50.400[T] KOG1354 Serine/threonine protein phosphatase 2A, regulatory subunit  ali follow..  13  14FSQVKGAVDDDVAEADIISTVEFNHSG-ELLATGDKGGRVVIFQQEQENKIQSHSRGKSLEIEEKINKIRWLPQKNQFLLSTNDKTIKLWKVEASPRRIFANAHTYHINSISINSDYETYLSAD-DLRINLWHLEITDRIKPANMEELTEVITAAEFHPNSC-NTFVYSSSKGTIRLCDMRASALCSFFSEIISSISDVKFSHSGRYMMTRD-YLSVKIWDLMENRPVETYQVHEDKFECCWNGSDSVVMTGSNNFFRMFDRNTKRDITLEASRKPRTVLKPRKVCASGKRDFNKKILHTAWHPKENIIAVATTNN-LYIFQDKV. 446
69 -49.900[R] KOG2444 WD40 repeat protein  ali follow..  14  4............EFDNPPLCMKSNKDG-SRLVVGFVDGSIRFYDTQQHEEE--FQEIWKFQTKSSIRGVDLDEHKKRVYAVTKNRSLCVFDIDTGKRVRCIKCHRSVPTAICTLPKSQQLATADESGEVKTWNLDPEENANIRKWQEQDEDINDLKVDVKSN---LLATSSDGTLGAYDLRKAKLKMRSELMHSEL--YSVCGTNRSVYVGGEDGYVEVFNLNEYGNLLE-GFEMGVNGIVELRSGLLGLTSQSNRMRLLNVQPSKRLGYAGYH-------------GDEKSDDDGIDAITISTDKSTVTMISMSCTIKKWDMGP. 308
70 -49.200[A] KOG0647 mRNA export protein (contains WD40 repeats)  ali follow..  16  22EKDLANDIVINSPAEDSISDIAFSPQQDFMFSASSWDGKVRIWDVQNGVPQG----RAQHESSSPVLCTRWSNDGTKVASGGCDNALKLYDIASGQ-TQQIGMHSAPIKVLRFPSNTECIVTGSWDKTIKYWDMRQPQPVSTVMMPER---VYSMDNKQSLL--VVATAERHIAIINLANPTTIFKATTSPLKWQTRCVACYNEADGYAIGSVEGRCSIRYIDDGMQKKSQSLVYPVNSIAFHPLYGTFVTAGDGTFNFWDKNQRHRLKGYP-------------------TLQASIPVCSFNRNGSVFAYALSYDWHQGHMGNR. 342
71 -49.200[KL] KOG4283 Transcription-coupled repair protein CSA, contains WD40 domain  ali follow..  17  1.....MWEAIKDRETGRIRSNSFA----------NRFKSRRILSLQ-----LSNRKDFVSPHRGSVNSLQVDLEGRYLLSGAADGSAAVFDVQRATDKQHENGHKYAISSAIWYPDTGLFITGSFDHYLKVWDTNTAQAVVDFKMPGKVYRTAMSSMAMSHTL--IAAGTEDVQVRLCDIASGAFSHTLSGHRDGVMSVEWSTSSEVLYTGGCDGAIRFWDIRRAGCFRVLDQS--QTQLGFRPPILKRTAVGSKVCS.................................................................... 254
72 -49.000[R] KOG2919 Guanine nucleotide-binding protein  ali follow..  15  113.ELGRRCWTSSTEAQHYTKGCYWSPDGT-CLLVPVHLDGMHVIEMPSDRSLTKLQSEVHVPEGGTVYDCVWYPHMNLWLATRQHEPIHMWDAFDGSLRCSYSGYDMAAISLAFSHDGEQIYAGY-KRCIKIFDTSRPGR--FCDDYPVKFAISCIAQTTAHP-HTLTCGNWHGYIQHFDLRCSHPLFTLGGHKGGITQLRYGEFGNLFSGARKCDKILQWDMRNKQPLVELQRHVDTNQFDLASDSNWLASGDRGFVNVWDLKKYGDPSVLPLHCNGVALNPAMPILATSSGGTETTELPAPADVNQNQKEVLYENAVVMWWCGQ. 485
73 -49.000[R] KOG0322 G-protein beta subunit-like protein GNB1L, contains WD repeats  ali follow..  10  11.........SLRSPDGAVNSLCFQESDR--LLAGTIKGSVFLWDLQ-----TNRSALHFEVGSDPITSLHHTPDR--LVTQEKGGTITMFSIGGSSYVKELGFCRSALHTNTSKTNEQLLFYPCEESSIGVLHVTDAAAPTQDPQLPKLGSVTCFKPFECASQLFLLAGYESGHFLTWDISSSVIL-DVMELAQDATSVDYDPVTNRGIVGGPTDKLISFSYQRSSMQMQLGKNPGVNGVRIRPDQKVFASAGDGRIRIFSWKSLRPLAVLTQH------------------KNGGVMDLAFSSQAPIMAAAGMDGQISLWDLYN. 323
74 -48.600[T] COG5170 Serine/threonine protein phosphatase 2A, regulatory subunit  ali follow..  14  16.CFGDKGDVEDITEADIISAVEFDHTG-DYLATGDKGGRVVLFERNHSKKEPEFDYLKSLEIEEKINKIRWCKRTNHFLLSTNDKTIKLWKLYEKNLKVVANAHAYHINSISVNSDAETYISAD-DLRINLWNLSISDHIKPENMEELTEVITSAEFHPINC-NHLMYSSSKGNIKLLDLRQSALKSFFSEIISSISDVKFSQNGRYILSRD-YLTLKIWDVNMKAPVKTIPLHDDKFECTFSGDDKHVLSGSSNNFGIYPTDSSLPGDRGQIVLQADMGSASVGLDPDNLDYNKKILHASWHPFEDSVAIAATNN-LFVFS.... 461
75 -48.400[R] KOG2321 WD40 repeat protein  ali follow..  10  51............EYPEASNRIKCTRDGKYAMATGVYKPHIKVFDFAE-----MSLKFERHTDAENVQFEILSDDWTKSVHLQTDRTVDFLNLEQGRFLNPLKSPTGGVNVIDINPMHQLLAFGTDAGSVEFWDPRDRSRVPSTPYSDNSRSVTALKYRNDGL--NVAIGLSDGATLLYDLRSSSPYMSDQGYSMPIKSLHWMDDGTARVLSADSKIIKIWEKDTGKPFSSIEPTVELNDVCPIEGTGLILTANGSPMHAFYIPSLNPAPRWCSFLDNI------------------TEEMEENPDDYKFVTKKELLNLGLDHLVG. 403

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zhao Y, Hong DH, Pawlyk B, Yue G, Adamian M, Grynberg M, Godzik A., Li T. The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesis. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3965-70. Epub 2003 Mar 21.