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Query: [A] KOG0306 WD40-repeat-containing subunit of the 18S rRNA processing complex, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGLTKQYLRYVASAVFGVIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAYLQEIEDPEEPDPKKIKGSSPGIQDTLEAEDGAFETDEAPEDRILSCRKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLELFCILSKKEIQKKMDKKMKKARKKAKLHSSKGEEEDPEVNVEMSLQDEIQRVTNIKTSAKIKSFDLIHSPHGELKAVFLLQNNLVELYSLNPSLPTPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTMTCEYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLILEEEREMEREAEYEESVAKEDQPAVPGETQGDSYFTGKKTIETVKAAERIMEAIELYREETAKMKEHKAICKAAGKEVPLPSNPILMAYGSISPSAYVLEIFKGIKSSELEESLLVLPFSYVPDILKLFNEFIQLGSDVELICRCLFFLLRIHFGQITSNQMLVPVIEKLRETTISKVSQVRDVIGFNMAGLDYLKRECEAKSEVMFFADATSHLEEKKRKRKKREKLILTLTLast
1 -223.000[A] KOG0306 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali  100  1MGLTKQYLRYVASAVFGVIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAYLQEIEDPEEPDPKKIKGSSPGIQDTLEAEDGAFETDEAPEDRILSCRKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLELFCILSKKEIQKKMDKKMKKARKKAKLHSSKGEEEDPEVNVEMSLQDEIQRVTNIKTSAKIKSFDLIHSPHGELKAVFLLQNNLVELYSLNPSLPTPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTMTCEYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLILEEEREMEREAEYEESVAKEDQPAVPGETQGDSYFTGKKTIETVKAAERIMEAIELYREETAKMKEHKAICKAAGKEVPLPSNPILMAYGSISPSAYVLEIFKGIKSSELEESLLVLPFSYVPDILKLFNEFIQLGSDVELICRCLFFLLRIHFGQITSNQMLVPVIEKLRETTISKVSQVRDVIGFNMAGLDYLKRECEAKSEVMFFADATSHLEEKKRKRKKREKLILTLT 943
2 -125.000[A] KOG0291 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  12  1.........MKFSYKFSNLLGTIYRNGNLVFTPDGNSVIS-PVGNRITVYDLKNNKSRTLSLESRYNYTNIALSPDGSLLIAVNEKGEAQLISMMSCTVIHRH-KFQTGVQCICFSPNGAFFAVAVQNVVLIFCAYNPFVLRRRFLGGFDDVTWLDWSSDSRLLAIGCRDSSTKIVAINYTKRTYNLSGHTDAIVACFFEANSLHLNTISRNGQLCLWECSLAPS---------DLEDAERPKIAPPQRKKEKKAVSDNESEDDVENVVEKDAESTKEAEDVNHIKNEDETKSHPFFYKKITRHYLADEP-----RKEQRDVQLTAANYNTRTKVLVVAFSSGAFYLYELPDVNMIHSL-SISDYPISAALFNCTGDWVALASREIGQLLVWEWQ--------SEQYIMKQQGHSSEMTCIAYSSDGQFIATGGEDKVKLWNTQSSFCFVTFSEHTVTGIQFSRNKKFLVSSSLDGTVRAFDVNRYRNFRTFSPNPAQFSCVAVDYSGELVVAGGQDVDIFLWSVKTGKLLEI-----------ISGHEGPVVSIAFSPTSSTLVSGSWDKTVKIWNCLESNSEHETIDAVSDVTNVTFSPSGEEIAVATLSGNITIFDIKSAGQVTTIEGRNDYFSTIEYSADGECILAAGKSANICIYHVREAILLKKLDGLNDFISRKHLSEFGNMALVEGGRVAIRLPGVQRGDMSRFQQEVRVFSVKFSPT----GQAFAAAGTEGLCIYAKGVVFDPFDLSLEVTPKAVHESLKQQNYTKALVMSLKLNEPNLIA------------------LVLERVPYKDVELVCADLSPEFAQRLLQQLARQLQSTPHIEFYLQWSCCLLTKHGNQDGVFQ--HTGLLALHEVLSRKYEMLNKICDYNKYTLKVLLDRADKLEQKNEGKPNATEEDSDEEMLLIRS....... 924
3 -111.000[A] KOG0319 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  15  1MTEPIKEIAAKRS-------EAVYTGGTVRWSANGQKLFSTC-TNVVKVIDLADNTASYTIGDPEDEITCTAVDKNRNRLLVAYNNQIIREYSIPLDPSTTKKTIHTAPILVMEFNEEGHLLATGSADHIVKVWNLTEQQCTHTLKGP-SVVSAILFGKHEK-LVVGYIEGQLNLYNIAPKKLVNTWKSHNSHITALLQVPDSRVVVALSRDQTMSIHETETQETLRVL-----------------------------------------------PLYESIEGGAIGHNGN-LFTVGEEGVVKEFVIETAKLVRKKRIASSNLDHLAYDVVSNRFLAISAEQNLIILDFENLKIARQIVGFHDEIYSCCLLGKDES-HMAVASNTSEIRLYNTK--------TLDCQLIRGHTESVLSVVSPTWDTSLLASCSKDSIIFWRLVTSPEND-------------------------------SCSTLVPVAAATGHANTVTALAISNTGRFLASVSTDCTIKLWGLGVSTKLKEVKIPKLTCSSTMVAHGKDVNCVDISESDALIATGGMDKLVKLWQVDTHKIAGTLSGHRRGVGDVKFAKNSHKLASCSGDMTIKIWNISEKSCLQTISGHSCAVFRVIFARNDSQLISADSAGIIKIWTIKTADCECSIDAHTDKIWSLSKNHNESEFVTAGTDGRIVVWKDVTEEKQKAEDNKRREAIEQDQTL----TNLLSQKRYSEALVFALTLAKPFCAFKVI-------------------------------------------------ALMAEETPEELGSAIRRLDTRQIEILLQFTVKWNTNSRTSSVAQRVLYEIVHIVDEELVSMPGAYGYIESFLPYTQRHMDRLDRAKQ-DVSLFDFVWRQMR................................. 790
4 -109.000[BK] KOG1063 RNA polymerase II elongator complex, subunit ELP2, WD repeat superfamily  ali follow..  13  5........TKVEAKRVFIGAGCNRVVNNVSWGASG--LVSFGAQNAVAVFCPKTAQILTTLPGHKASVNCTHWLPDRQYLLSGDSDGIIILWELSTLNVLQLPLSHKKGVTCIMVSETDAMFASASSDGVVNVWDVSFPVCLDSICVDTKAIVTLSLNPGRFALALGGLDNKIKLYSGERTTSVCELKGHTDWIRSLDFSLPLHMLVSSSQDKVIRIWKLVLVGD------------VGSWRREITLASYIEGPVFVSGTFTYQISVE----SVLIGHEDWVYSVEWQPPVISILSASMDKTMMIWRPEKKTGVWVNVVCVGEL------------------------------------SHCALGFYGGHWSPNSL-SILAHGYGGAFHLWRNVSSSKE-SENWQMQKVPSGHFAAVTDVTWARTGEYLLSVSQDTTRVFSAWKNDEGNEAEDENCVAMVQGKGNHRFVSGAEEKVVRVFEAPLSHTCAGGEGSFPEDLQADVQVLGANMSALGLSQKPIYLH-------------SSSEPLERNGGGEGLDTFETVPEAAPAELKEPPIEDQLAFHTLWPESHKLYGHGNELFSLCSDHKGNLVASSCKAQSIWLWEVGTWKAVGRLQSHSLTVTHLEFSYDDTLLLSVSRDRHFSVFSIQRHKLMAKVEAHKRIIWACSWNPFGHQFATSSRDKTVKIWSVENDALVLPPFGSSVTAVAWTGLDNEKSGCVAVGMESGLIELSNVKIIEPFMCHVSAVNRLAWRPTEKCLTSCGDDNCVRVFNF............................................................................................................................................................ 838
5 -109.000[R] KOG1539 WD repeat protein  ali follow..  14  5.............EPFRAIGYITSTVPFSVQRLGTETFVTVSVGKAFQIYNCAKLNLVLLKPKLPKKIRALASYRDYTFVAFGN-----EIAVFRRAHQVATWSKHVAKVDLLLVF--GEHVLSLDVEGNMFIWAFKGIEEHLALTGKFTPTSIVHPDTYLNKVLVGSQEGPLQLWNINTKKMLYQFKGWGSSVTSCVSSPALDVVAIGCADGKIHVHNIKLDEEIVTFE-------HASRGAVTALSFSTDGRLLASGGSFGVISIWNLQSVIRDAHDSSIISLNFLANEPVLMSASADNSLKMWIFDTNRLLRFRSGHSAPPLCIRFYSNGRHILSAGQDRAFRLFSVIQEQQSREL-SQRHISRRAKKLRLKEE----------ELKLKPVVSFDCAEIRERDWCNVVTCHMDTAEAYVWRLQNFVLGEHILKPCPENPTPIKGVFVSRNHLLILACAISACGNFAVVGTAGGWIERFNLQSGISRGSYYAHDGEVIGVACDSTNTLMISAGYHGDLKVWDFKKRELKSQ------------WDVGCSLVKIVYHRVNGLLATVADDFVIRLYDVVTLKMVREFRGHTDRITDLCFSEDGKWVISSSMDGSLRIWDVILAKQIDGV-HVDVPITALSLSPNMDVLATAHSDQNVYLWVNQSGLPSVESYASGKDVVNVKLPSVSALTSSEADDDMDRQVLENSEALISQKQIPELVTLSLLPKSQ-----WQSLINLDIIKARNKPIEPPKKPEKAFFLPSIPSLSGDILFKANDSEADGENEENNKKDSKHLKSSWDSKHFLDFTNYMKSLSPSALDMELRMLEFILIGQLLDYFINEVSCKNDFEFMQAVVKLFLKIHGETIRCHPSLQEKAKKLLETQSLVWQKMEKLFQSTRCIVTFLSN.................................... 928
6 -101.000[Z] KOG0318 WD40 repeat stress protein/actin interacting protein  ali follow..  13  11..........NKNIYATLPRTQRGQPIVLGADPKGKNFLYTN-GNSVIIRNIENPAIADVYTEHSCAVNVAKYSPSGFYIASGDASGKIRIWDTVNKEHLLEFQPIAGPIKDISWSPDNQRIVAVGEGREGHVFMSETGTSVGEISGQSKSINSADFRPARPFIVTGSEDNTIAVFEGPPFKFKMTKQDHSRFVQAVRYSPDGKFFASAGFDGKVFLYDGTSSELVGEFG--------------------------------------------SPAHKGGVYALAWKPDSTQLLTCSGDKTCRLWTVESRELVSE------------------------------------------FVMGTTVDDQQVSCLWQGD-NLITVSLSGVITYLNVADP-------SKPLRVVKGHNKPITVLGLSDDRSTIYTGSHDVVTNWNSGSGTNDRTGTGHGNQINGIAAWGDFVYTCGIDDSLRQFSVEGNSYTDYVVKLNCQPRGLAILRNENIIALACIKELTLVQDQKKIF---------------SLPIKYEASSIAVNADTSDVAVGGDDQKLHIYTLKGGVLEKVELDHLGAVTDVSYSPDLKYLVACDAHRKVVLYSVEEYKPAHNWGFHSARVNTVAWSPNSLLVASGSLDTTIIIWSVANPKHTIIKNAHPQSQITRLVWLDNNTVISTGQDCNTKVWHVEN............................................................................................................................................................................................................................................. 607
7 -94.000[U] KOG0276 Vesicle coat complex COPI, beta` subunit  ali follow..  12  3..........LRLEIKRKLAQRSERVKSVDLHPTEPWILASLYSGTLCIWNYQTQVMAKSFEVTELPVRSAKFVARKQWVVAGADDMYIRVYNYNTMDKVKVFEAHSDYIRCVAVHPTLPYVLSSSDDMLIKLWDWEKGACTQIFEGHSHYVMQVTFNPKDNTFASASLDRTIKIWNLGSPDPNFTLDAHQKGVNCVDYFTGGDYLITGSDDHTAKVWDYQTKSCV----------------------------------------------QTLEGHTHNVSAVCFHPELPIIITGSEDGTVRIWHATTYRLENTLNYGLERVWAIGYIKSSRRVVIGYDEGTIMVKLGRE-----------------------------------------------------IPVASMDNTGKIIWAKHNEIQTANIKSIGADEVTDGERLPLSVELGTCDLYPQSLKHNPNGRFVVVCGDGEYIIYTALAW------RNRSFGSGLEFVWSSEGECAVRESSSKIKIFSK-----------------NFQEKRSIRPTFSAEKIFGGTLLAMCS-SDFICFYDWAECR---LIQRIDVTVKNLYWADSGDLVAIASDTSFYILK-FNRDLVTSHFDSGRPTEEEGVLHENDERVRTGIWVGDCFIYNNSSWKLNYTMYHLDRPMYLLGYLASQSRVFLVDKEFNVIGYTLLLSLIVMRGDLDKASEILPTIPKDQHNSVAHFLESRGMIEDALEIATDPDYRFE----AIQLGRLEIAQEIAVEVQSESKWKQ---------LGELAMSSGKLQMAEECMKYAMDLSGLLLLYSSLGDAEGVTKLATLAKEQGKNNVAFLCLFML-RIPEAALMARSYLPSKVSEIVALWRKDLSKVNSKAAESLA---------DPEEYSNLFEDWQVALSVEAKAVETRGVY..... 819
8 -88.900[S] KOG2106 Uncharacterized conserved protein, contains HELP and WD40 domains  ali follow..  12  1.................MALCYQRYLLALYHPPPGSGKILLCQQPKVALLNECLLGVEGKAMGIPEETGIAQAPPAALPVAKKNSESKPKEPVFSAEEGYVKLFLRGRPV--TMYMPKDQVDSYSLEAKVELPTKRLKLEWVYGYRGR-DCRNNLYLLPTGETVYFIA--SVVVLYNVEEQL-QRHYAGHNDDVKCLAVHPDRITIATGQVAGTVRIWDSVTLNTLHVI------GIGFFDRAVTCIAFS------------------------------------KSNGGTNLCAVDNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGEITSLLLDTRRKLPLIRSRTRKAKVVLCVTFSENGD--TITGDSSGNILVWGKGT-------NRISYAVQGAHEGGISPLCMLRDGTLVSGGGKDKLISWSGNYQKLRKTEEQFGPIRTVAEGKGDVILIGTTRNFVLQGTL-SGDFTPITQGHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGHR------------PVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVESDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQHIYGGHSSHVTNVDFLCE---DSHLISTGGKDTSIMQWR.................................................................................................................................................................................................... 715
9 -86.000[S] KOG0271 Notchless-like WD40 repeat-containing protein  ali follow..  16  2..............................................................TESPQISVSFVSEDENELGGSGILVPVDISTNELQILCQLLGSSDDPVPISFFTTEGAEIVDSIRKSLEEIRVRPVTRCSASIPGHGEPVISAQFSPDGRGLASGSGDQTMRIWDIELELPLHTCKSHKSWVLCIAWSPDATKIASACKNGEICIWNAKTGEQIG-------KTLKRHKQWITSLAWQPMH---------------------------------KDPTCRLLASCGKDGNIFIWDTVQGTVVR----------------------------------------------------------------------------------------------CLSGHTASVTCLRWGGEGL----------------------------------------IYSGSQDRTVKMWRADDGVMCRNMTGHAHWINTLALNTDYALRTSCFEPSKRCIKPDTVEECQKVAQTRYE--------------AALEIAGGERLVSGSDDFTLFMWNPETKQSINRMTGHMQLVNQVVFSPDTRYIASASFDKSVKLWCGRTGKYLASLRGHVGPVYQVAWSADSRLLVSGSADSTLKVFELKTKSLYYDLPGHGDEVFTVDWSPEGTKVVSGGKDKVLKLWRQ............................................................................................................................................................................................................................................... 473
10 -84.400[S] KOG0308 Conserved WD40 repeat-containing protein  ali follow..  12  1.....................................MSSCVNTSQTGPKKISFIIRDEHEYSNRSAVSALQYDAQNGRLFTGGSDTIIRTWSVPHHKDAGSLEQHTDWVNDMILCGHGKILISASNDTTVKVWNIERDNFIDCIRTHKDYVSCLAYAPIVEKAVSASFDHNIFVYDINANKTVNNLIGCKDSIYSLATTPNLSLVLGAGTEKCIRLFDPRTNEKI----------------------------------------------MKLRGHTDNVRALVVNDDGTRALSAGSDATIRLWDIGQQRCIATCIAHEEGVWTLQVDSSFTTVYSAGKDKMVVKTPLY----------------------------------------------------DFTKSQLLFKEEAPVKKLLLSEKDNLWVGTWKSDIKRWSIRPSAQLSIGEDGPSTSNANHSVSASSSPPVTFKYIRVKDQKGQQSTELVIPGAPAIKKHAMLSDKRHVLTRDSDGNVALYDVLAARKIKDYGKR------IFEEVVDENSRQVYIPSWFVVDSKSGMLQITLDELDALS-------------SWLSSKDAGFDDNDTKQIIVNYGGM-------MLRSLFERWPPCKMTNVDAADADDVQKATLNFISLPEHTPLIICEGNGRPLYRLLVGDAGKEFEANELAQIAPMWVID---AIERNQLPKFNKMPFYLLPHPSTNPKQPKKD----RLSATEMLQVKKVMEHVYEKILSTNDVGSIPLNQIHTKMEM............................................................................................................................................................... 648
11 -83.900[D] KOG0642 Cell-cycle nuclear protein, contains WD-40 repeats  ali follow..  14  147...............................PQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALLGFSIDVTDRE------------DDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESAAADFSDDVDGREKSVIDTSTIVRKKALPDSGEDRDTK----EALKEFDFLVTSEEGDNESRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKEQYKKER--------------------------------KGKKGVKRPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSGKSFIMGADEALESELGP----------GELAGLTVANEADSLTY-DIANNKDALRKTWNP-------------KFTLRSHFDGIRALAFHPIEPVLITASEDTLKMWNLQKTAPAKKSHKGPVLCVVMSSNGEQCYSGGTDGLIQGWNTTNPNIRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFNDIK-------ELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLENSSCQINRVISHPTLSISITAHEDRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHEESIHDVAFHPSKCYIASAGADALAKVF................................................................................................................................................................................................................................................. 779
12 -80.400[R] KOG1524 WD40 repeat-containing protein CHE-2  ali follow..  1...................................................MKLKLSASRKTRHTEMVCGVGWIGTEA-ILSAADDHVFLLTNTATNESQQILNMPETFFRSQTKGGQNDVFAVSTSDGKINILS-RNGKVENMVDAHNGAALCARWNSDGTGLLSSGEDGFVKMWSR-SGMLRSVLAQFATAVYCVAWDSTSSNVLYCNADHCYIKSLKMQVAPIK-----------------------------------------------WKAHDGIILCCDWNPTSDLIVTGGEDLKFKVWDG-FGQILFNSSVHDYPITSISWNTDGTLFAVGS---------------------------------------------HNILRLCD---------KSGWSHSLEKMNAGSVMALSWSPDGTQLAVGTAGLVFHAHIIDKRLIVQTQKTVIEVRDVSSEVSRETLETKERISKIIYIYSSKNWNTPTMIEYNERTVNIIVQCEKIFLVSDGMTITIFTYE--------RKLINLNPPGQVMALLDERKIDLANDTLVVRDRADNKVLHFFDPTTGKAQGDNLKHEHDIVELTVNQCGRNVAFRDQIGAVHIAMVKTFGVSQRMVKIGSLVEQLVFNDVTNMLCGIS-EGKIAVWPLPNVAHDRNLLQKSLIQKNIGSVGKFPQLANFA-GNTIVIRKSDGCLLGILPFYGTLITMASQSKW---DQAIRLCRSIGNDTMWATFAGLAVLHKNMIVMEIAYAALEDDEKVSLINEIKDKTDKETRQAMQVVLTGKLADADVLLERSGLSFRSLMLKRALELGL-QWLEIVMGYREKYLKNCGQKETDPLF-----------LKHMSEVEIDWVHIRELIAAEKAKGNN.................................................. 760
13 -77.500[A] KOG0285 Pleiotropic regulator 1  ali follow..  15  2..................................................................................................................................IALNREVETQSLKKLSLKSVRRAREIFSPVHGQFPQPDPESKRIRLCHK----------------------------IQVAFGGVEPASKPTR---------------------------------------------IADHNSEKTAPLKALALPGPKGSKELRKSATEKALVVGPT-LPPRDLNNTGNPGKSTAILPAPGSFSERN----------------------------------------LSTAALMERMPSRWPRP----EWHAPWKNYRVLQGHLGWVRSVAFDPSNEWFCTGSADTIKIWDVATGVLKLTLTGHQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKVIRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVWDIRTKMQI------------FVLPHDSDVFSVLARPTDPQVITGSHDSTIKFWDLRYGKSMATITNHKKTVRAMALHPKENDFVSASADNIKKFSLPKGEFCHNMLSLQRDIINAVAVNEDGV-MVTGGDKGGLWFWDWKSGHNFQRAETSEAGIYAACYDQTGSRLVTCEGDKTIKMWKEDED------ATPETHPLNFKPPKE....................................................................................................................................................................................................................... 473
14 -77.300[S] KOG0772 Uncharacterized conserved protein, contains WD40 repeat  ali follow..  12  2.................................DDNTAPKKNSEKKARVFDLQNAPRTEEPTHVPQSVSVSSKSESGVSSSAVSDDEDDFMPDLPPGF--QMQQSEAGPSSSRAEGPEDSDDSDFDETEAISIIKLIPAACEAKISHGTQAISALRVEPPGVRFASGGLDYYVKLFDFQKMDMSELLPAESHVINSLAFSPNGETLVVASGEAIIRLLDRAGKQWSETVRGD----------------------------------QYIIDLNITKGHTATVNCVEFNPLNKEFISCSDDGSLRLWNLDDHKVITKCINKHRKVIKTK------------------------------GANGKRVSPQVCTFSPDGKW-IAAGCDDGSVQAWKYGSQYVNVN-----YLVRKAHNGSITSIAFSPDSKRLLSRGFDTLKMWSLDNPKEPLLVNAFKSTDCGFSPRAEVVFTGTTPGTLQFFDPMTFDLVYKIDYPGISCHRIQWHPRLNQIIAGLSDGTIHVYYDQTMSQRGV-----------MSCVTKPLKRNRASEVV------------------------REDMVLSPLSLEMFQPRGEEGEEKEVTGWRIKKYLRMQNKLRPEFRKPADMPINGKSANGRVAASGGSLHSYLAKQIGTARNAEFLKDT---------DVRASILKHAKDAEENPLYIDKAYR---KTQPKKIFQETAVEPEDQDDEELQPVFK............................................................................................................................................................................................................ 615
15 -76.500[B] KOG0273 Beta-transducin family (WD-40 repeat) protein  ali follow..  12  1...............................................................................MSITSDEVNFLVYRY--------LQESGFSHSAFTFGIESHISQSNINGTLVPPSAL--------ISILQKGLQYVEAEISINKDGTVFDSRPIESLSL-IVAVIPDVVQMRQQAFGEKLTQQQASAAATEASAMAKAATMTPAAISQQNPPKN----REATVNGEENGAHEINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRH--------------------------------------------------------------------------------CIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDFARIWTE-NGNLASTLGQHKIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMT-FASCSTDMCIHVCRLGCDHPVKT-----------FQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQGT-GGIFEVCWNARGDKVGASASDGSVCVLDL............................................................................................................................................................................................................................................... 522
16 -75.700[D] KOG0267 Microtubule severing protein katanin p80 subunit B (contains WD40 repeats)  ali follow..  12  2.................SLCGHTSPVDSVAFNSEEVLVLAGASSGVIKLWDLEESKMVRAFTGHRSNCSAVEFHPFGEFLASGSSDTNLRVWDTRKKGCIQTYKGHTRGISTIEFSPDGRWVVSGGLDNVVKVWDLTAGKLLHEFKCHEGPIRSLDFHPLEFLLATGSADRTVKFWDLETFELIGTTRPEATGVRAIAFHPDGQTLFCGLDDG-LKVYSWEPVICRDGVDMG-----------------------------------------------WSTLGDFCINEGKFIGCSYYRNSVGIWVSDISEGAVSEDKNECMVKRFSVLNDQSERMGSGPRGSV----------------------------------------------------------------SPDYETREIKNIYVDSTGGNLNVAQPGSLKATLPLESGKVATMVSEKQNAAYFGPAGDKYSSYSERESIPFSRTKSGMLLRPAHVRKT---LAKFEESKQSAVVQSATRKKSGLAVEEEPQTQNAFLSEQNASKPFDAEDSIIKGITNKFEKALSSEPPTDEANRMFLKPPRIHRSSNSKYNDTRRAMSADPATFGKGGMENSGDVEIPSKTERVLSREKPGDEQKNTEYPSGSRELNPVKIVEGVNVVSGRTRS--LVEKFERGEKTTHTEGASTTIEQNNNAVQEDPRKTSRQTGETPVISTRRARSTPARVMPIVLNRDSNVTSDEPPLTQPARTSSFPVMPVILNQIQPACDNMPQKEEPNISDREDDSDITENLMLTHNEFLSTLQSRLTK---LQIVRHFERSDVKGAIGAL--DQSVDVISILTE--IEILTLDMFSQLVPVLTSLLGSRTVSLDMLLKLVAVFGTVIRSTVSAPRI-VGVDLHANERNLP-GTAQDSKNSSSSRKKRRSNNKKGSRTKPSSSRTIA 968
17 -75.500[S] KOG0283 WD40 repeat-containing protein  ali follow..  143...................KKMNHEVDEQDHDHVPVMLARSRSESDIERFLIE--------KRRKEEILGKISKQRLTRTYSTICPTRTRICQYQTPIRQTPAVCGNGKALRGGGEALTSVMSNARVGAFFLIKNLDTGKEFIVNEYDEDGMNRLSDLQTGKQLTLEEFEKCVGY-ELMRRENVNRINYEPLMDLRKFNSYLSKSVRLSKRRGAALLKNIKGVA------HSMSLRVADKDVSDGSTDSPKKGKDHKHGKANEWVKVRPHMCQEIQAHEGAVWTIKFSQDAHYLASGGADRVIHVWEVQECELMSMNEGSLTPIHPSLCDSSGNEITVVEKKKKGKGSSGRRHNHIPD----------------------------------YVHVPETVFSFSDKPVCSLKGHLDAILDLSWSKSQLLLSSSMDKTVRLWDIETKTCLKLFHNDYVTCIQFSPDENYFLSGSLDAKIRIWSIQDRH-VVEWSDLHEMVTAACYTPDGQGALIGSHKGICRAYDTEDCKLSQTN--QIDVQSNKKSQAKRKITSFQFSPVNPEVLVTSADSRIRILDGSEVIHKFKGFRNTCSQLSASYSQDGKYIICASEDSQVYLWKNDFHRTRSTLTTQSHEHGHVRGEPPPVQIHSKRHSKRISTSSQPSSTISSPTKEETSATGPTTSNRNKKSGLPPMPKKAATKSQIQPEEEAELGSSESFRSSMNSSE----QHSSRFGESPSINTSSRLSSWSWFDSGGHGPQTIQPTAWGMVIVTATVHGEIRSYQNFGLP-----RRIGRQTT........................................................................................................................................... 901
18 -75.100[B] KOG0639 Transducin-like enhancer of split protein (contains WD40 repeats)  ali follow..  13  221..................................................SNDIKKRKVDDKDSSHYDSDGDKSDDNLVVDVSNEDPSSPRASPAHSPRENGIDKNRLLKKDASSSPASTASSASSTSLKSKEMSLHEKAS-TPVLKSSTPTPRSDMPTPGTSATPGLRPGLGKPPAIDPLVNQAAAGLRTPLAVPGPYPAPFGMVPHAGMNGELTSPGAAYASLH--------NMSPQMSAAAAAAAVVAYGRSPMVGFDPPPHMRVIPPNLAGIPGGKPAYSFHVTADGQMQPVPFPPDALIGPGIPRHARQ----------------------------------------------------------------------------------------------INTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLATPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQ-----------FQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQH-DFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPD-KYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASI-FQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVI.............................................................................................................................................................................................................................................. 769
19 -74.800[S] KOG0282 mRNA splicing factor  ali follow..  15  2...........SAAIAALAASYGSG------SGSESDSDSESSRCPLPAAD-SLMHLTKSPSSKPSLAVAVDSAPE---VAVKEDLETGVHLDPAVKE--------------VQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFATYDNHQVSAKYIGSVEEAEKNQGLTVFETGQKKTEKRKKFKENDASNIDGFLGPWAKYVDE---------KDVAKPSEEEQKELDEITAKRQKKGKQEEEKEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPK--------------------------------------------KQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGE-------RRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDYLKLWDTETGQCISRFTNRKPYCVKFNPDEDLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAE----------PSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAVWHPETSKVITCGWDGLIKLWD.......................................................................................................................................................................................................................................................................................... 579
20 -74.700[T] KOG4378 Nuclear protein COP1  ali follow..  11  1...................................................................MMSNLVEPSWRLLAASG-GDTVKLFDVSADSVLSYTPSPGCAVNSVKWNHTNLVVASTGEDKKISLWRKNGQSGKDGGDSAEECLSAISFSKKGSYICSGGTGQIVKIWDLQRKLCIKKLKGHTSTITGVMYNCKDEHLASVSVGGDLIVHNLASGARATELKDPN---------------------------------------GQVVQFVHVLRLLDYSRSSRLLVTAGDDGTVHLWDTTGRSPKMS------------------------------------------WLKQHSAPTAGVCFSPSNEKIIASVGMDKKLYTYDSGSRRS---------SSCIAYEAPFSSLAFGDNGYILVAGTSNRVVFYDIRGKPQPVTVNSEDVTSLSWQTSKPVIVNEKNYTSEMALLGSTVEIPDPLPSTTPSASQSAMAPGSRGVSASTVNASSVEQTPNRNHLWPS---------GPLGRLHALRANDSYNDDMGVFSPIIDVSSVEKWADSEGYNNKDHLVVDNKPSSLLFPSSSKGYSFGSKEHPIFDWKPSSTS--KQDDPRAAFSSFGSITPTASSKSEDSALTPPEAWGGDKFSEKFNQLANEKFSDKFSHLHAPSRLAVSSTGASTSGSMFSRDFPLSHGQTNFANASLEFPRIRDFSSTFETSSTQTDNNLPSSPLFTKGITAPGNIDSLRLSPNFTRRFSTYAERISTTSSFSDGASLSLGGSPKIKKTGSETREEVLNHLLAR-PETVVATEAGAMPLMNGGLKQSQTDQQQVMGSSNFTLQLFQ---------RTLEGTLDSFQNSIHDDVR--------NLH-IEILRQHMHEMEMSKVLSSILENQAEQMKERKENQELRQRL. 787
21 -73.800[R] KOG2394 WD40 protein DMR-N9  ali follow..  10  2MNTSNGMISAPSSSSSPAANPQSPGIKTYFKTPEGKYKLHYEKTHSSGLLHYAHGKTVTQVTIAQLKPSTPTGTSSGYSASSGFRSATARLLGTGNGSRALSFVGGNGGGKSVSTSSRISGSFA--------------------ASNSNTSMTNTNFDGKGTYLVFNVSDAFICDLNSQEKDPVKSIHFSNSNPMCHAFAKDGHDLLIGLNSGDVYTVSLRQQ------------LQDVSKKLVGALHYNKDGS--------------------VNNRQDRCTSISWVPGGDAFVVAHADGNLYNKD--------------------GATESTFPAIRDPTQFSVDKAKYSKSNPV----------------------------------------------------ARWHICQGSINSIAFSNDGAHLATVGRDYLRIFDFLTQKLVCGGKSYYLLCCSWSMDGKYILTGGEDDLVQVWSMEDRKVVAWGEGHNSWVSGVAFDSNWSSPNSDGSG----------------------------------------EHVMYRFGSVGQDTQLLLWDLEMDEIVVPLRRAPGGSPTYSTGSSAHWDNVGTLQPAPCKRDVPKLSPIIAHRVHTEPLSGLMFTQES--VVTACREGHIKIWTRPSEQTNSSEANPTTALLSTSFTKDNKASLSSKIISGSTFKQ................................................................................................................................................................................................................................................ 556
22 -73.500[K] KOG0263 Transcription initiation factor TFIID, subunit TAF5 (also component of histone acetyltransferase SAGA)  ali follow..  12  133..................................................HVAEDRTAQQYRQNKYQLSRITFDLLLHFLFENVSNGGSIIIKLINQHIDIHIVPNAKVINEQEGITGQSFERGDAQLQPVKLQQMPMDKEMEKIVEMDLEEEDMMHQNDPNNQSPKLLKEFRKLHEPNAEDAPSRDYIPLPPHKGVDILSEVEAVKDWSKRLHLGPRASLPSVCM----------------------------------------------YTFHHTNNNMNCAEFSPDSTMIACGFQESYIRLWSIKADKKSLPKSTS---------------------------------------------------------------------------------VEDSDGSVRLLSHSGPVYGTTFSPDNKYLLSCSEDSARLWSVDTKTALVAYKGHTVWDVAFGPFGHYFATASHDQTAQLWSCDHIYPLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCRLWDVHRGHSVRV-----------FNGHTQPVTAVAIAPDGHTMASADSEGLIHLWDIGTGRRIKTMRGHRGNIYSLSFSRESTVLVSGGSDCTVRAWDVFKTNYNNPVSSSLTGSVVTPFSAKTSTFNE--------VNWSTSPDQMVALYTKQTPIFNVSFTRRNLCLAISVS........................................................................................................................................................................................................................................................ 643
23 -73.200[S] KOG0295 WD40 repeat-containing protein  ali follow..  17  10....................................................EINRAIAEYMQNNGYSESFSVFLKESSLSENDIKPLGGILEKKWTTVLRLQRKVNDLESKLQESQREINHGAPTRDKRQAADWIPRPPETQKLTGHRLPITRVIFHPLWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFGQT---------------------------------------------YDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVY----------------------------------------------------------------------------------------------TFRGHNDWVRMIRISNDGTLFASASL---------------------------------------DQTVTVWSFATKSAKLVLRDHEHAVECVEWAPDTA--------------------------------------YTNVTGQQPEGNSTHILFSGSRDRSIKAWNINTGDVLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWELSAQRCMKAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVWECR........................................................................................................................................................................................................................................................................................ 404
24 -72.700[A] KOG0284 Polyadenylation factor I complex, subunit PFS2  ali follow..  11  4................GMMRGNQMPNVTLTIQPSTSSMQNSQPRIMNNHHHPHNRF------QREHVMPDVMGDGPGRRLRKNVANVRRHV-TVLNHCENRLWQYGKQRILQQPDILYQQYAVPADSTPDVPVDCILTKFIRTAMNKVKCPVYSVCWSPEGKRLITGCQTGEFTLWNGTAFNFETILQAHDSAIRALKWASNEQWLLSADQGGYVKYWQPNMNNAH----------------------------------------------MFSAHKDEAIRGLAFAPTDVKFATASDDGTARVWDFARYTEER----------------------------------------------------------------------------------------------VLRGHGAEVRCIDWHPTKGLIATGSRDPVKIWDPKSGSCLATLQEHSVMAVEFNKNGNWLLTGGRDHLVKMYDIRMMKEMRTYRAHKKEVISLAWHPIHELFVSGGGDGSIVYWMVDGEKEIGLLEH----------AHDQAIWSMKWHPLGHILATGSNDNNTKFWARNFGLSNTNMIGHLDKEREPRMAPPKPSIETQETYRPDTFIPGMGLDLYEQLNRDHNMMTTDSTLLVPDDLTRQNFAPMIGAKRTLIKQPPKKAQRQFERMWNNSKGIGAGSDDFTTMKGGLGREDAEGAQFPTTGGSLLGPSQPRPQEFRSVPPPQQQQGPPPNWRHQGPPMSGPGQGYGPPGRMGGNQGGWQRPPPQGSYGGQGPPQGSYGGQGT..................................................................................................................................................... 655
25 -71.800[A] KOG1272 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  14  1................................................................................................................MEISSEDNNLMEKVLPPVEQVLTWTLIQICMQESDVELETKVKKYLRGEGANLETLKDKKLKTQLASREKLYGKSAKAAAKIEKWLLPAEAGYLETEGLEKTWRVKQTDIANEVDILSSRNQYDIVLPDFG--------------------------------------PYKLDFTASGRHMLAGGRKGHLALLDMMNMS-----------------------------------------------------------------------------------------------LIKEIQVRETVRDVAFLHNDQFFAAAQKKYAYIYGRDGTELHCLKERGPVARLRFLKNHFLLASVNMSGQLHYQDVTHGGMVASIRTGKGRTDVMEVNPYNSVVGLGHSGGTVTMWKPTSQAPL-----------VQMQCHPGPVSSVAFHPNGHLMATSGKERKIKIWDLRKFEEVQTI--HSFHAKTLSFSQKGLLAAGTGSF--VQILGDSSGGSSHNSMVKGYQIEKVMFRPYEDVIGIGHSMGWSSILIPGSGEPNFDSWVA-NPFETSKQRREKEVLLDKLPPETIMLDPSKIGAM-RRKEKPSRGEIEAEKEVAIEAAKNKTKGRNKPSKRTKKKKEMVENAKRTFPEQEHNTAIKKRRIVEDAAA................................................................................................................................................................... 535
26 -70.600[R] KOG0288 WD40 repeat protein TipD  ali follow..  13  19....................................................DALRALRKRHLLEEGAHAPAISALSKPLISQGSEWKEKTEKL-ETELQQCYKAQSRLSEQLVIEVAESRTSKAILQEKELLINDLQKE-LTQRREDCTRLQEELEEKTKT-------VDVLIAENLEIRSQLEEMTSRVQKAETENKMLIDRWMLQKMQD--AERLNEANDLYE----------------------------------------------EMLAKLKANGLETLARQQVDGIVRRNEDGTDHFVES---------------------------------------------------------------------------------------------TIPSTCANRIHAHEGGCGSIVFEYNSGTLFTGGQDAVKMWDTNSGTLIKSLYGSNILDMAVTHDNKSVIAATSSNNLFVWDVSSGRVRHTLTGHTDKVCAVDVSKFSRHVVSAAYDRTIKLWDLHKGYCTNT------------VLFTSNCNAICLSIDGLTVFSGHMDGNLRLWDIQTGKLLSEVAGHSSAVTSVSLSRNGNRILTSGRDNVHNVFDTRTLEICGTLRASGNRLASSCISPDDDYVAAGSADGSVHVWSLSKGNIVSILKEQTSPILCCSWSGIGKPLASADKNGYVCTWT................................................................................................................................................................................................................................................ 515
27 -69.300[R] KOG4227 WD40 repeat protein  ali follow..  10  7..................LGGSMRSVVGFLSQRGLHGDPLLTQDFQRRRLRGCRNLYKKDLLGHFGCVNAIEFSNNGQWLVSGGDDRRVLLWHMEQAKPIQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVILHDVESSETLDVF-AHEDAVYGLSVSPVNNIFASSSDDGRVLIWDIRESP-PFCLANYPSAFHSVMFNPEPRLLATANSKEGVGLWDIRKPQ-----SSLLRYGGNLSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHSRLGYFNSCTMKSCCFAGDRQYILSGSDDFNLYMWRIPADPEFMVLKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSPYKQPGCTGDLDGRIEDDSRCLYTHEEYISLVLNSGSGLSHDYANQS-------VQEDPRMMAFFDSLVRREIEGWSSDSDSDLSESTLQLHAGVSERSGYTDSESSVDESADNAFHLGPLRVTTTNTVASTPPTPTQRLSALRRYQDKRLLALSNESDSEENVCEVELDTDLFPRPRSPSPEDESSS---------SSSSSSSEDEEELNERRASTWQRNAMRRRQKTTREDKPSAPIKPTNTYIGE--DNYDYPQIKVDDLSSSPTSSPERSTSTLEIQPSRASPTSDIESVERKIYKAYKWLRYSYISYSNNKDGETSLVTGEADEGRAGTSHKDNPAPSSSKEACLNIAMAQRNQDLPPEKEETPRTPSNGPGHEHSSHAWAEVPEGTSQDTGNSGSVEHPFETKKLNGK---ALSSRAEEPPSPPVPKASGSTLNSGSGNCPRTQSDDSEERSLETICANHNNGRLH-PRPPHPHNNGQNLLEVVAYSSPGHSDTD--DNSSLTGTLLHKDCCGSEMACETPNAGTREDPTDATDSSRAVHG---SGLK--RQRIE-------LEDTDSENSSSEKKLKT......... 942
28 -68.900[R] KOG0286 G-protein beta subunit  ali follow..  19  1.............................................................................................................................................................................................................................................................................................................................................................MGEMEQLRQEAEQLKKQIADARKACADV---TLAELVSGLEVVG--------RVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDKLIVWDSYTTNKVHAIRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETGQQKTV-----------FVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESCGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN................................................................................................................................................................................................................................................ 340
29 -68.000[I] KOG0301 Phospholipase A2-activating protein (contains WD40 repeats)  ali follow..  10  1..............................................................................MADDGLGDVPMETESMPQYTISHVIEAHKSDTKALAVTQGGC-LISGGRDETVKFWAKKGKQTHAFEQPKGITVNSIAYAEDGWRLFVGRRDGTIAVFGPSQAEPYAIFNEHKQNVCCLHINEKATHMLSGSWDSNVIIWPITELNS----SSFTTIVCPGHTLSVWALASFPDL-------------------------------------PNTYLSASADKTIRMWF------------------------------------------------------------------------------------------------GDTTLSVFKGHTDVVRALVVLSSSHFLSAGNDGHIIHWDVASASILRKFATQAEFIYSMTLSDSHILTTGEDGTLEFWAIDGGKSEAVIQLPTTNTWDAKVLLNSD-IAVAGSDGRIYIMTTDKNRKADD---------DILDAFDAEVVAKLTAKTERMKQEEHETVTIKVDDRPTQLNLKYKKGTDPGLCAQEFLSENNLPIHYLEEITRFIKDLKSGKKVIVDGKEYDYALGVNFGKGEPDKQMPFNVNESPQFAAQRFVERHQLPVSPSLAGMISQEMDKLSKGAASAQSGYEDPFTGPGRYVPQGSSNSGGHGADPFTGSGR----YVPQASNSSGFDTGFSGDPLTGDGGYRASAPENTGSHAVPLSSLPQNKKKPRGPLVPVPDFYIIGLAGKGE----KAIAKLKELNEKQDAFQLNPDQINGLEELFVLPTSSNYSSEVTQSAFEMSLQWPVEHLTPVLDFLRIAQELVGRLIAILVSDPADVALKVLVCRCIANAFSHPVGRNLFASTELSTRQVLNEKTVLQMSAATA. 756
30 -68.000[S] KOG0296 Angio-associated migratory cell protein (contains WD40 repeats)  ali follow..  16  1...................................................................................................................................................................................................................................................................................................................MAEEEENQELYIAENEVEEVKLMDQGVTEDEAEQEQNDTMNNMVMDMSVQGF-FEHKDSVFSVSINPVHSNLCASGGGDDLGYIWDIT--------TGEQICQLTGHKDSIVAIDWSFDGTYIATGGDSQVRLWKSSTGFEFITATVDEIVWLSWHPKGLFLAAGCNDGSIWMWSLPSGKVVQVMYGHTAPVNAGKFIPPGKRLATVDDSGTLIVWNPATGAPECRMSSDDHRFDPGNEETAAGWTSFDCNAEGNVLFLGGSSGKVKVVNINSSHILASLEAQTESVEAIALCTALPICACASVDGTVALYDSASLKFRKSL-PHEQAVIDCKFLPNTPYLLTACADCVIRKWDVRSGQLLGEYTGHQEPILCMAITPDGKRVVTGSDDTELLVFDCEH............................................................................................................................................................................................................................................. 399
31 -67.700[R] KOG1310 WD40 repeat protein  ali follow..  10  1...............MDNLSFHDGNIFNLLHTRSQDPSHEVDQRMQFHSSLVRRLSQEQELEGHQGCVNALAWNSNGSLLISGSDDLRINIWNYSSRKLLHSITGHTANIFCTKFVPEDELVVSGAGDAEVRLFNTSRLSGSALYQCHTRRVKKLAVEPGNNVVWSASEDGTLRQHDFRESTALADPPKQTLSLKSCDISARPHLLLVGGSDAFARLYDRRMLPPLASSRKR-------------------------MPPPPCVNYFCPMHLSERGRTNLHLTHVTFSPNGEEVLLSYSGEHVYLMNVNNGTGIMQYTPGDVDNLFSFSNNLHDVESPPQVSTTPQNGFHRSSNAATVKKCTELVEIAKWSLEEGTDVFYAIEAANEVLDAHSNDIESALRHECLCTRAALLLKRKWKNDAHMAVRDCHNARRIDAS--------------------FKAHYYMSEALQQLGKCKEALDFATAAQHMNPSDADIVAKVESIKRDLQAAGAEKNEETGAGTTRVLSLSDILYRSEANSDSSHDMSRSEREDSDYDEELELDIQTSLSDDEGRDTDSNSMRGSLNLRIHRVGDDKPMENTVDNASSGTASSSQNDRTSYQPEGAIDMKRRYVGHCNVGTDIKLGQRGEYIASGSDDGRWFIWEKQTGRLMKVLVGDESVLNCIQCHPFDSVVATSGIDNTIKIWSPTASVPSIVAGGSAGPATANVVEVMESNQQKLSRNRENPLSVELMQRFRMQEFAEGNFHPFECTQS.............................................................................................................................................................................. 754
32 -67.700[R] KOG2096 WD40 repeat protein  ali follow..  13  2...............................................................................................................DSVLVVGIASVILGALIAVLFFGSYFRKRTSEVQSMAKAEPQDPIRNPKSNHPAPKKNHPKSQASDKNQNKDLNTLKGHGDAVTGLCFSSDGKSLATACADGVIRVFKLDDASSKSF------------------------------------------------NRWEFTLQAHFHDLTVFFVCFLKFRFLRI---------------------------------------------------------------------------------------------------------NLPAGGHPTAVAFADDASSIVVACHHM-----------------SGSSLYMYGEDKQKDQQGKLPLPSIKWDHHHIHEKRSVLTISGATATYGTADGSVVIASCSEGTDIVLWHGKTGRNLGH-----------VDTNQLKNHMAAVSPNGRFLAAAAFTADVKVWEIVYQKRVMQLKGHKSAVTWLCFSPNSEQIITASKDGSIRVWNINVRYPLCDSGGNPLHYDRLSLCPEGKILAASH-GSTLQWLCAETGNVLDTAKAHEGDITCISWAPKAMVLGTSGDDKKVKLWEAPKSQSL......................................................................................................................................................................................................................................... 454
33 -67.600[A] KOG0272 U4/U6 small nuclear ribonucleoprotein Prp4 (contains WD40 repeats)  ali follow..  15  2................................SDDDDIQYIKRQRTLHYGSLEESERKRQ---NAAASGAAATTTSGTTASSGAGTTTT-GTGGQLEDIDSDEDYEESTKKTSNAKQAGAPPPTAATLANKIDDDYFDLE-MEMERDKVALLEEFERKKRARQINVSTDDTEIKSNLRQLNE-LKELLAGLGENAINKRQYEDEERKQQQREQDQATWYHEGPDSLR--IARLWLADYSLPRAKDRLVRAREALEVPSAARAGRMVEMLAPLCSQVGDTRPVSSAAFSEDSSLLLTSSWSGLCKLWSVPDCELKQ----------------------------------------------------------------------------------------------TLRGHASYVGGVALRPGVK--------------------------------ADEENVVAMASGGHDGAVKLWGFNNEESIADITGHPHRVSKVAFHPSGRFLATACYDSSWRLWDLEQKTEVLH-----------QEGHAKPVHCLSYHSDGSVLVTGGLDAFGRVWDLRTGRCIMFLEGHLGAVFGVDFSPNGFHIATGSQDNTCKIWDLRRRQPVYTIPAHTNLISDVKYQQEGSFLVTCSYDSTTKIWSNKTWQPLKTLQGHDNKVISVDIAPNSQYIATTSFDRTFKLWSPDS............................................................................................................................................................................................................................................. 553
34 -67.400[R] KOG0289 mRNA splicing factor  ali follow..  15  1MSLICSISNEVPEH---CVSPVSNHVYERRL----EKYIAENGTDPINNQPLSEEQLIDKVAHPIRPKPPSATSIPAILKALQDEWDAVMLHSF-------TLRQQLQTT-RQELSHALYQHDAACRVIARLTKEVTAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQKL-QDKATVLTTERKKRGKTVP----EELVKPEELSKYRQV------------------------------------------ASHVGLHSASIPGILALDLCPDTNKILTGGADKNVVVFDKSSEQILA----------------------------------------------------------------------------------------------TLKGHTKKVTSVVFHPSQDLVFSASP---------------------------------------DATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDE---------TSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQDNNFEVKSLIFDQSGTYLALGGTDVQI--YICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL............................................................................................................................................................................................................................................... 504
35 -66.100[A] KOG0640 mRNA cleavage stimulating factor complex; subunit 1  ali follow..  15  2....................................................................................................................RDEILDPSNLVKNREILYRLMISQ--LMYDGLEKFAMELSMLVKADQCAPSERLLHVMIAGMQTSDKDKTNSDDVLPGIDLEFEPEASALAPEPHSYETAY---------------------------------------------------------VTSHKQACRAGAFSCDGSLVATGSVDASIKILDVERMLAKSAPEDIEPGRE----------------------------------------------------------------------------QQGHPVIRTLYDHTDEVSYLEFHPKEHILASAS---------------------------------------RDGTVKLFDIAKPSVKKKVFTDCEPVLCLSFHPTGDYVAIGTEHNVLRVYDVATTQCFVSA--------IPSQQHKAGVTCVKYSPTGKLYATGSYDGDIKIWDGISGRCINTIAEAHAAICSLEFTRNGKYLLSSGMDSLVYLWELCTSRPIQTYTGQEHQTEAVFNHTEDYVLFPDEATTSLCSWNSRNGCRLLNSLGHNGPVRYITHSPNGPAFLTCSDDFRARFWYRRANN........................................................................................................................................................................................................................................... 423
36 -65.500[A] KOG0265 U5 snRNP-specific protein-like factor and related proteins  ali follow..  19  1..........................................................................................................................................................................................................................................................................................................................................................MGTKRPNNSVILAQEAKRSKNDLMAYTNRDKA-LLESGVRRTSNLQAP-------------IMQLEGHEGEIFTAEFHPEGELLLSSGFDQIYIWQVYEDCENVMAHSGAVMEAHFTPDGSHIFTCSTDKTLAFWDIATGQRQRRFKGHGNFVNSVQGSRRGQQLLSGSDDRTIKIWDARKKHAA------------HTLESPFQVTAVCFGDTGEQVISGGIDNEVKIWDIRKQAVLHHLRGHSDTITGMSLSPEGDFILTNAMDNTLRVWDVRGERCVKVFQGHQHNLLRCAWSPGSDKITSGSADRHVYIWDVNTRRILYKLPGHNGSVNAVDFSPKEPLILSGSSDKTLYLGEIDE............................................................................................................................................................................................................................................. 347
37 -65.100[A] KOG0268 Sof1-like rRNA processing protein (contains WD40 repeats)  ali follow..  15  2..................................................................KVKMLSRNPDNYVRET----------------------KLDLQRVPRNYDPALHPFEVPREYNATKLERVFAKPFLASLDGHRDGVNCLAKHPEKATVLSGACDGEVRIWNLTQRNCIRTIQAHEGFVRGICTRFCGTSFFTVGDDKTVKQWKMDGPGYGDEE-------------------------------------------EPLHTILGKTVYTGIDHHWKEAVFATCGQQVDIWDEQRTNPIC----------------------------------------------------------------------------------------------SMTWGFDSISSVKFNPIETFL--------------------------------------LGSCASDRNIVLYDMRQATPLKKV-ILDMRTNTICWNPMEAFFTAANEDYNLYTFDMRALDTP----------VMVHMDHVSAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSREVYHKRMQHVICVKWTSDSKYIMCGSDEMNIRLWKANASEKLGVLTSREKAAKKFQHYPHIKRIARHR-HLPKSIYSQIQEQRIMKEARRRKEVNRIKHSKPGSVPLVSEKKKHV-VAVVK.............................................................................................................................................................................................................................................. 445
38 -64.900[R] KOG0315 G-protein beta subunit-like protein (contains WD40 repeats)  ali follow..  16  1.............................................................................................................................................................................................................................................................................................MGDQQQLILATGGYDHTIKVWQAHTGNCIKTMRVETSQVNALDRTPDKTRLAACG---------------------------------------------YQCIRLYDLESN------CTAPVINFDGVQKNVTRLGFQEDGNWMFTAGEDHVRIWDMIAAPPHCSRCEAPVNAACLHPNQVEIAMGSQNGSVFLWDVKSERHERIVPEVDASIQDVAISPDGRYLAAANNKGNCYIWSLTSQDQKMSTLRPN----RKIPAHSRYILRCKFSPDSRLLLTTSGDGTVCIWKTDDFSKWRELCIENYWVWDAAFSADSKWLFTASSDGIARLWKLQTKSSIRDYTGHTKAITALSFKDEIPVKSTNISDVQSSAKP------PTQRDNPPGTNNLAFFETVGRVAMNPYMGNTTTELN................................................................................................................................................................................................................................................ 362
39 -63.100[J] KOG0650 WD40 repeat nucleolar protein Bop1, involved in ribosome biogenesis  ali follow..  177............................IGYDWDAKKIIKPPQGDQITVKDPLTGQDVRLTDEDIALIKRIV-DHKRSFLPSVSEKKRVS-WMKTTEEVEREKQAKRGPKFYMLWETDTSREHMRRIHDPVSAGHAESYNPPPEYLFDAKETKEWLKLKDEPHKRKLHFMPQKFKSLREVPAYSRYLRERFLRCLDLYLCPRAKRVKLNIDAEYLIPKLPSPRDLQPFP---------------------------------------TVESMVYRGHTDLVRSVSVEPKGEYLVSGSDDKTVKIWEIATGRCIRTI-----------------------------------------------------------------------------------------------ETDEVVRCVAWCPNPKIIAVATGNRLLLVNPKVGKVLVKKTDDLLAEAPSQDVIESERIKTAVQWSNAEADEQEKGVRVVITHFKPIRQVTWHGRGDYLATVMPEGANRSALI---------QLSKRRSQIPFSKSKGLIQFVLFHPVKPCFFVAT-QHNIRIYDLVKQELVKKLLTNSKWISGMSIHPKGDNLLVSTYDKKMLWFDLDSTKPYQTMRLHRNAVRSVAFHLRYPLFASGSDDQAVIVSHGMVYN-LKKLQTHEFGVLDVNWHPVQPWVFSTGADSTIRLYT................................................................................................................................................................................................................................................ 784
40 -62.800[S] KOG0310 Conserved WD40 repeat-containing protein  ali follow..  11  4........................................................................................................................................................................................................................................................................................................................................................................................................PYLPAEKFLSRKQETILLDEDEPAVVSSVRISPKKPYHVATTSSRLTLYDTVVCEPLNLFSRKGVCSIDFRHDGRLLAIGGDEGKVRIFDVSSKVALRVMQASQSTVKSVHFSPRGDTVFSMADDGKIKQYRVADTAYGVN-----AVPIIEIQAHEDAIRCGAVSSNDHIVLTGGYDHKVRLWDIRSKEKSLEL-DCEHPVESVLFLPGEQLIATAA-GPIVKIWDTTTGRQLTALQAHYKTVTSLRLATNSTCLLSAGIDRRVNAFRTTNYSLINSW-SMPSPVLDIDVSRDDQTMAIGMGNLLALYRRAEIKKEASAAIEDKRSLIRTSAP----PVKLVEKDRDMQKVVAKNADKLKIPKIDGMLSNFKHAAVIKLLFGGK-----------------------RSAMDTAVVSYLRVIMRGAIHRALAGQERSVQKNILVFLNHNLYKAQYFSTLKEVVNAFFDVYALEK-LDKDVVKHVQSLRGSLGRELEVQKMISSL-IGSIDLISSSTALIEDNDVFGEPTIRARDLDELKPSDQGA..... 536
41 -62.600[JT] KOG0643 Translation initiation factor 3, subunit i (eIF-3i)/TGF-beta receptor-interacting protein (TRIP-1)  ali follow..  13  4........................................................................................................................................................................................................................................................................................................................................................................................................................ILLQGHERSITQIKYNREGDLLFTVAKDIVNVWYSVNGERLGTYMGHTVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALL-KTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDNNEPYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTF-RTERPVNSAALSPNYDHVVLGGGQEAARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFE....................................................................................................................................................................................................................................... 322
42 -62.600[T] KOG0279 G protein beta subunit-like protein  ali follow..  23  2.................................................................................................................................................................................................................................................................................................................................................................................................................AEGLVLKGTMCAHTDMVTAIATPVDNSDVIVTSDKSIILWKLTKEDKRMTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLATGESTRRFVGHTKDVLSVAFSTDNRQIVSASRDRTIKLWNTLGEC---------KYTISEADGHKEWVSCVRFSPNTLVIVSASWDKTVKVWNLQNCKLRNTLAGHSGYLNTVAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLEAG-SIIHSLCFSPNRYWLCAAT-ENSIRIWDLESKSVVEDLKTKVIYCTSLNWSADGNTLFSGYTDGVIRVWGIGR............................................................................................................................................................................................................................................. 325
43 -62.500[S] KOG0316 Conserved WD40 repeat-containing protein  ali follow..  14  1....................................................................................................................................................................................................................................................................................................................................................................................................MSATEL---------PTKEAHILKGHEGAVLAARFNGDGNYALTCGKDTIRLWNPHRGILIKTYKSHGVRDVHVTSDNAKFCSCGGDRQVYYWDVSTGRVIRKFRGHDGEVNAVKFNDSSSVVVSAGFDRSLRVWDCRSHSVEPV-----------QIIDTFLDTVMSVVLTKTEIIGGSVDGTVRTFDMRIGREMSDNLGQ--PVNCISISNDGNCVLAGCLDSTLRLLDRTTGELLQVYKGHISKKTDCCLTNSDAHVIGGSEDGLVFFWDLVDAKVLSKFRAH-DLVNSIDVDFYLRKFFVAGDKRELPPEGRLYVDFFGR--YNSCLEKMKKQQILTSIDFVIYVSNSPFFFYYR.................................................................................................................................................................................................... 342
44 -61.900[S] KOG0293 WD40 repeat-containing protein  ali follow..  14  76................................................LYSLGYDKTGAMLEEESGSLHNSTIKLFLQQVKDGKWDQSVKTLHRIGFPDEKAVKAASFLLLEQKFLE-RNEMAPLRINTKRVHELASSLISPSSFISHTTSTPGKESVNSRSKVLEELQTLLPASVIIPEKRLECLVNSLHIQRDSCVFHNTLDSDLSLYSDHQCGKHQIP-----------------------------------------------SQTAQILESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEISADGHISLKH-------------------------------------------------------------------------------------------TLVGHHKPVIAILWSPDDRQVLTCGAEVIRRWDVDSGDCVHMYEKGGPISCGWYPDGQGIIAGMTDRSICMWDLDGREKECWKGQRTQKVSDIAMTDDGKWLVSVCKDSVISLFDREATVE-------------RLIEEEDMITSFSLSNDNKYILVNLLNQEIRLWNIEGDPKISRYKGHKRSIRSCFGGYKQAFIASGSEDSQVYIWHRSTGKLIVELPGHAGAVNCVSWSPTNHMLASASDDGTIRIWGLDRINQQNQKLVQGSSSNGVIHRCNGN............................................................................................................................................................................................................................................................... 589
45 -61.600[S] KOG1409 Uncharacterized conserved protein, contains WD40 repeats and FYVE domains  ali follow..  11  2................................................................................................................................................................AAIINQRVEQGESSMGG-AKPALLHRITGHVARINDVILLSKDEGVWTASDDRSVRLYLKRDNDQFWP--------------------------------------------SIHHFMPVAPTSLYYSEETYKLLVGLINGNVYEFSVADDFN------------------------------------------------------------------------------------------SMTESRKWTCHAGPISGLGFALSSELIFSCSRDKSIVWHCSENSNKMGSYLLENSCTAMVIDLPFVFVGDHGGHVTVLRIVDNQLVSKLSAHTNAITSLTWDGNKKVLYSGSSDHLIIMWDIGGGRG----------EAYELNGHNGKVTTLCAAPAAKRLFSADEHGKLMCWDMNCKRVETPEWKTSDCCQKCPFFWNLQAMWQRKVVGLRQHHCRTCGS-----------AVCGSCCDNWTTYPPMGYETKIRICNDCNLTPLAIPHEIHTGITAMHLQETLGLLVTSGQNRVIMIWDVRSVCSAPSGSQ.................................................................................................................................................................................................................................... 415
46 -61.000[S] KOG0321 WD40 repeat-containing protein L2DTL  ali follow..  12  2...................................NMDIGKALSDVGGLRDITSANNSLPPTPDSSPAAPSKKHKLYDFLESRGKIETPRKRIVPAQLCKELLIRQLGGSRSHPFSTKTSRHVGGRLNLETYYSRPSE-----CLMMLNQLPFCLGFANNESLLAVCTETGALELFDSRSARRIHGWLAHNNAIFSVNFSKDDSLLATSSGDQTSKVFDLSTQQCITRLGRR----------------------------------------GVDGYHSHSVKQVNFCNDSPNLVSCSRDGSIIFWDMRTHGITIDGEHFQKPVLRIRKAH------------------------------------------------------------------------------ENSGRDCSITSATWLPQSTVISSCSANSLKLWDLRTVHTVRPLP------------------------------AATTPELTTSKRDFGVTNVCTSPDGERIYAASRDSIIYEYSSRHLN-----SGFCKTYKDPRLRISSFYVKLACSPDGATLACGGKTSGVVVFDTTRNSSAMLTGGHTKDVTAVDWSSEGQ-LASISDDGSVRVWNSSLHGSAANLEKNFSEIFYWGFSEK........................................................................................................................................................................................................................................................................................................... 490
47 -60.400[R] KOG1273 WD40 repeat protein  ali follow..  12  2.......................................................................................NAPIIDPLQGDFPEVIELEHGVIKCVAFNHRGSLLAAGCADGGCVIWDFETRGIAKEIRDNSAAITSVSWSKYGHRLLVSAADKSLTLWDVSTGEKIARTILQ-QTPLQARLNPGLS----------------------------------------------------------------SPSLCLACPLSSAPMIVDFDIDCTTLLPVSVPEMPDVLAPPQRS-----------------------------------------------------------------------------------------------KCPESNPPFSPAAACFNKCGDLVYI---------------------------------------GNSKGEILIVDYKSVRVLALVSSGAAPVKNIVFSRNGQYLLTNSHDRTIRIYENLLPAKNKMKTVGSKFREFQDSVTKMHWKAPCFSGDGEWVVGGSAEHKIYIWDR-AGHLVKILEGPKEALIDLAWHPVHPIIVSVSLAGLVYIWAKDYTENWSAFAPDFKELENEEYVEREDEFDLIPETEKVKVLDVNEDEEVDIDTVEKDAFSDSDMSVEELRYLPAEPIPDTN----DQQDNLVESIKLIEGQISASPQNGHHASSPQAGKKDSNSVI...................................................................................................................................................................................................... 474
48 -60.300[S] KOG1407 WD40 repeat protein  ali follow..  16  2................................................................................................................................................................................................................................................................................................................................................................................................EETTIPFKSLHSR------------EYQGHKKKVHSVAWNSNGTKLASGSVDTARIWNIEPHGHSKAKHTDSVDQLCWDPKHSLVATASGDKSVRLWDARSGKCTQQVE-LSGENINITYKPDGTHVAVGNRDDELTILDVRKFKPL------------HRRKFNYEVNEIAWNMPGDFFFLTTGLGTVEVLSYPSLKPLDTLTAHTAGCYCIAIDPKGRYFAVGSADSLVSLWDISDMLCLRTFTKLEWPVRTISFNYSGEYIASASEDLFIDIANVQTGRTVHQIPCR-AAMNSVEWNPKYNLLAYAGDDKNPKYNTDEGVFRIFGFESS................................................................................................................................................................................................................................... 315
49 -60.300[R] KOG2055 WD40 repeat protein  ali follow..  11  14.................VFGNINNFSSFLDKENETFDVMMNEAPELSEDNDAQEDELEKLEDAELFMFDTGSADGAKDSVPLDIIAGDNTVKEDEEASNEIP-SDDERLMISLQDHSRLRKLRQYEDEDMVNGLQYAR-----RLRTQ-----FERVYPVPEWAKKQDVTEEEDEFNALSEKSVIPKSLKSLFKSSVSYINQSSKLLAPGTINIKRLKDANF----------------------------------------------------QAPSHSGIRCMSIHPYFPLLLTCGFDRTLRIYQLDGK--------------------------------------------------------------------------------------------VNPLVTSLHLRSSALQTALFHPDGKRVIAAGRRYMYIWDLESAQVQKVSFQPSMERFHVDPTGKYIALEGRSGHINLLHALTGQFATSFK-IEGVLSDVLFTSDGSEMLVLSYGAEVWHFNVEQRSVVRRWQV----------QDGVSTTHFCLDPSNKYLAIGSKSGIVNIYDLQTSKPVTTLDNITFSINSMSFSQDSQVLAIASRKDTLRLVHVPSFSVFRNWATPLGRVTCLAFGKGGE-LCVGNEAGRVGLWKLAHYDLKFVPDKII--NWEIRLGKFGYVLLGIQVDVVI.................................................................................................................................................................................................................................................... 555
50 -60.200[R] KOG0645 WD40 repeat protein  ali follow..  17  1...........................................................................................................................................................................................................................................................................................................................................................................................................................SGHTGRLWSVAAHPMLPLFATSSQDSVRIYNSNTYNLVHVIHTRSIRRVAWRPIERVLAVASFDSVVSINEKIDWECTAALEGHENEVKCIAWSCNGNYLATCSRDKSVWIWEATEDDEFDCL--------AVLQEHTQDVKVVTWHPTEDLLVSGSYDNSICFWRDDDWALTCQLQGHTNTVWALAFSPNGNTLASADNDGNVFLWIKISSNQTSLPHIHKGAVYTISWMNDAT-LCSAGGDGKIVVYQREKHDEEQDHAHGVYEINSLEYLRDDR-LLSGGDDGECRVWSFK.............................................................................................................................................................................................................................................. 322
51 -59.300[ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA cleavage factor II complex, subunit SWD2  ali follow..  14  2...................................................................................................................................................................................................................................................................................................................................................................................................KIKLID------SVVRSFKVAKIFRENTDKINAIDFAPNGEHLISCSEDQIVIYDCEKGTQSRTVNSKKVDLIHFTHANNTAIHSSVDDTIRYLSLHDNKYLRYFPGHTKKVISLCISPVEDTFLSGSLDKTLRLWDLRSPNCQGLM-------------HLSGRPIAAYDPEGLIFAAGVNSESIKLYDLRSFDTFKLNQEKECDWTGLKFSRDGKTILISTNGSVIRLVDAFHGTPLQTFTGYPNNPIEASFSPDSQFIFSGSTDGRVHIWNADTGNKVSVLNGHPGPVQCVQFNPKYMMLASACTNMAFWLPTSEEG............................................................................................................................................................................................................................................ 316
52 -59.100[S] KOG0281 Beta-TrCP (transducin repeats containing)/Slimb proteins  ali follow..  18  106............................................................................................................................................................................................................................................................................................................DARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSESRGWDQ-------YLFKNRPTDGPPNSFYRSLY-PKIIQDIETIESNWRCGRHN---------LQRIQCRSENSKGVCLQYDDEKIISGLRDSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGL--MVTCSKDRSIAVWDMASATDIT--------LRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQY--RDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDLQSTLCLRTLVEHSGRVFRLQF--DEFQIISSSHDDTILIWDFLNVPPSNETRSPSRTYTYISR.......................................................................................................................................................................................................................... 508
53 -58.700[DK] KOG0973 Histone transcription regulator HIRA, WD repeat superfamily  ali follow..  10  4..................VGHDTGSILAIDCHPSGKKFITCGSNGLVVVWNAEP-PKLLFQVESQSQSNSCRWSPDGKRFAFGSDDSSVSVWEYVGLKECCVLRGHSMEVLTVEWSPNGKYLASGSIDYRIIIYNARKPDRITVLNDIQLPVKGLSWDPIGKYLASLEGDKKLRFWATDSWQCVKSVTIEETMLTRLDWSPDGKYLMTPAAVRLIKLIQRQTWKSD--------QFLAGHHKGTTCVRAMPQLTCAAVGSRDKSISIWVFPGTFVINNIFNHTVMDFAWCGRNLLACSQDGTVKVIHLSESVEMISNEAMSDLCYQIYSIRPPRYELTDKEEDESQDSFNNNASFVTCPEDVLIKRKKLVAAQQSSDIQLTKSMEDNSKENESKNSEKTMMEERNKQIDVRKDGKRRIQPVFCGTTTADPMTSLSSEGKKTVAPPPAKRKALAPAVPAKKGEVDLEDSSDSDDDDEEEEEDMEISDIESVRNKKRKVPATTSQPMLALDLKKPALRPMEPKSLKTQEGTVLMEAPEQQPKLSQHVVDRKGMFVEIDNRWKHGGVETTTAENEDDMMDGERRVNHECLWMAVLGSPVIIVAANKHNVVLGCGDKCLRVYRTFCGTHIVSLRLDS---LPVLIGVTEHAAYALTENGRLSTWNLKLGKAVVT-ASTDNSLISADVSETGVPLIVFSNNVSLSCWIQAITTNVLGRLTSPISDAQLSCSNGTTNSAGPLVRLLKRM----RKQATAPGVAPQVVKAVKE---------------------------------------------------SQLEQLLHCAPQDYQTMLMLYVETLCEGGSEKKL--NILNDLSRSGAPMQVCGLRRSALYDDVTRMIKLKQPAIAA---------RIVAGVAASTTTKSLF......................... 927
54 -58.400[R] KOG1963 WD40 repeat protein  ali follow..  7...EVKKNDKDPWSKTAYLGGRLVSKIPAVYSNDNKFVFLTYD-TFIGIFSLITGDCINRIFFPNNLPVAVLLSPNAFELYVIFQSGYVCVHDWSNSELLRTMENEFLALDSSLRDNNLATVAVITTDKAIFSLNVPKKKRSQRWHLFNMPQKLTNVSLCGSACAVSDDEGKIHVINSNEKFNPQILHWHANPLNGLSWALNGEYLLSGGQEGVLVLWQMETSHR-----------------------------------------------QFLPRLGSSILSIATSHDSDSYALHLGDNSLVVIRAVDLAEQIHVSGINSFESKYLTSTGPKNTSKQLQGLVQFSSVSPNGELLSSSFNGHSVSVQEYDLTKDSTIRKFEAARYSYS----------SVSKNSDDATSLDNGHVGSVAVTSSRNGLYIATVKQTALKFWQFDSVQ-------------------------------KTWVLMT--RIDNPHGNLEVVTALKMMTSSNRFITVGTDATLRIWALLPGSSAWKCVAIHHFAQASIKQRYGFSKALTCSLDDSIIGFG-YGSCMHFINSETLEEISTVDLPHGGQLENAQFLNAEHCVIIS-QRRLLVWNVISASVQWTLASKFTGL--LASSSSGNDFAVIDFNSSLIIFSPDSPKIQSIHI-FKTLPVALHYLHGGFVVLD--NKSIIHVYAGDLTTKIPSAQLSIDNTSR-NVPLLNLENPISGSQGLHYKRLTTDMIHNLFNVPSNSPVNMQ.................................................................................................................................................................................. 772
55 -57.700[R] KOG4497 Uncharacterized conserved protein WDR8, contains WD repeats  ali follow..  13  1...............MNFSEVFKLSSLLCKFSPDGKYLASCV-QYRLVVRDVNTLQILQLY-TCLDQIQHIEWSADSLFILCAMKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEHLRITVWSLCTKS-VSYIKYPKACLQGITFTRDGRYMALAERRDCVSIFVCSDWQLLRHFDTDTQDLTGIEWAPNGCVLAVWDTCLEYKIL-----------------------------LYSLDGRLLSTYS--------------AYEWSLGIKSVAWSPSSQFLAVGSYDGKVRILNHVTWKMITEF-----------------------------------------------------------------------------------------------GHPAAINDPKIVVYKEAEKSPQLG--------------------LGCLSFPPPRAGAGPLPSSESSVPVSLQTLKPVTDRANPKMGIGMLAFSPDSYFLATRNDNNAVWVWDIQKLR------------LFAVLEQLSPVRAFQWDPQQPRLAICTGGSRLYLWSPAGCMSVQVPGEGDFAVLSLCWHLSGDSMALLSKDHFCLCFLEVVGTACRQLGGHT...................................................................................................................................................................................................................................................................................................................... 460
56 -56.900[R] KOG1334 WD40 repeat protein  ali follow..  13  229..........................................................SALPRSRWQVLTALRQRQLGSSARFVYEACGARTFVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFSGHDINVIQAKFFPNDSTLAMCGHDGQVRVAELINAENTKRVAKHRGPAHELALEPDSYKFLTSGEDAVVFTIDLRQDRPASK-----------------------------------------VVVTRENDKKVGLYTISMNPANYQFAVGGHDQFVRIYDQRRIDKKEN---------------------------------------------------------------------------------NGVLKKFTPHHLVYCDFPTNITCVVYSHDG---------------------------------------TELLASYNDEDIYLFNSSLSDGAQYVKRYKG------------------------------------------------RNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGRGDIVNCLEPHPYLPVLATSGLDQHVRIWTPT-AKTATELTGLKDVIKKNKQERDEDNLNYTDSFDNRMLRFFVRH--LLQRAHQPGWRDHGAEFPDEEELDESSSTSDTSEEEGQDR............................................................................................................................................................................................................................................ 675
57 -56.500[A] KOG0299 U3 snoRNP-associated protein (contains WD40 repeats)  ali follow..  10  57.......................................................................................................................................................................................................DEENEDTYETAAEKRLRL-EVKNELVEDGGFDAKEVDRELLASRLKEDVLEKKGQMYLDYTSKINPDVKIETAQLRGRHMRPLVGVVAYENF--VYSADKSGLIQKWEALQEKDTENRENDDHEIGKAIKLHFRP-------------------------------------------------------------------IKFSRSRRGENDHVKEITCLAISNDGRWIVTGGLDRIVIRDSVTLEPQHCWKHHRVMGLAMRRGTNEMFSCSADRSIKVWSLDQMSYIETLFGHQDVIFGVDALARERCVSVGGRDRTSRLWKIVEESQLVFRSG--GTSMKATAGYMEGSVDCVAMIDEDHFVTGSDNGVIALWSVQRKKPLFTYPLAHGLDPILAPGRHS----------------AETSPDPVTIPPQPRWITSLAAIPYSNLFASGSWDGNIRLWKIAEGLRSATPLSVYGCINSLSLSLQGKVFAACGRETRVGRWKTLRGIPNGFVFNIPLTVIPSVTDGDEIDE................................................................................................................................................................................................................... 524
58 -56.500[R] KOG2919 Guanine nucleotide-binding protein  ali follow..  11  4.............................................................HNVSFSSTMVTSNGDLSLPKLSVTLSAEEILKLRSGRPKNAVESPHAGVPMETSLAAEEEANGDEEEESVRVVDIEDTLELTSGNEAKPEDQELAIAPVLQYFQGALVELGRRCWTSST--------EAQHYTKGCYWSPDGTCLLVPVHLDGMHVIEMPSDLYSADTVQPQSEVHVPEGGTVYDCVWYPHMN-------------------------------SLQPETCLWLATRQHEPIHMWDAFDGSLRCSYSGYDA-----------------------------------------------------------------------------------------VDEVMAAISLAFSHDGEQIYAGYKRCIKIFDTSRPGRFCDDVKFAISCIAQTTAHPTLTCGNWHGYIQHFDLRCSHPLFTLGGHKGGITQLRYGEFGNLFSGARKCDKILQWDMR----------------------------------------------------NYKQPLVELQRHVDTNQRIQFDSDSNWLASGDTRGFVNVWDLKKYGDPSVLPLHSDCCNGVALNPAMPILATSSGQ---FHFTDQSAQGDNVTLNGTETTELPAPADVNQNQKEVLYENAVVMWWCGQT............................................................................................................................................................................................................................................ 486
59 -56.400[R] KOG0646 WD40 repeat protein  ali follow..  13  4.........................................................................................................................................................................................................................................................................................................................................................................................TVIASSSIDEGIGSWDLK--------TGTEQLQFKPCASPAHGLTAVGEKQLSARNTSGSIFYWSWTKPQAVKSYPVEPIKALAANNEGTYLVGGGISGDIYLWEVATGKLLKKWHGHYRSVTCLVFSGDDSLLVSGSQDGSIRVWSLIRLFDDFQRQQGNTLYEHNFNEHTMSVTDIVIDYGGCVIISSSEDRTCKVWSLSRGKLLKNI-IFPSVINALALDPGGCVFYAGARDSKIYIGAINATQVLGSVSEKGKAITCLAYCADGNLLISGSEDGVVCVWDPKSLRHVRTLIHAKGSRKGPVNNQIVRKTIVANSNKTQVSWKSRGALIPLEKYERPV-------EDTMDGIVTVDPPPFSDVPVYSSFLSADL............................................................................................................................................................................................. 380
60 -55.500[DO] KOG0305 Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits  ali follow..  13  37..................................................................................................................................................................................................................................................................................FDFANYALTQGSKRNLDEVTSASRKAYMTQLAVVMNQNRTRILAFRNKPKSLLSTNHSDSPHQNPKPVKPRRYIPQNSERVLDAPGLRDDFSLNLLDWGSAN---VLAIALGDTVYLWDASSG------STSELVTIDEDKGPVTSINWTQDGLDLAVGLDNEVQLWDCVSNRQVRTLRGHESRVGSLAWDNHILTTGGMDGKIVNNDVRIRSIVETYLGHTEEVCGLKWSESGNKQASGGNDNVVHIWDRSLASSKQTRQ-----WLHRFEEHTAAVRALAWCPFQASLLAGVGDGKIKFWNTHTGACLNSVETGS-QVCSLLWSQSERELLSGFTQNQLTLWKYPSMSKMAELNGHTSRVLFMAQSPNGCTVASAAGDENLRLWNVFGEP-PKTTKKAASKKYPELFSHVNSL.............................................................................................................................................................................................................................................................. 443
61 -55.400[Z] KOG1523 Actin-related protein Arp2/3 complex, subunit ARPC1/p41-ARC  ali follow..  13  1.......................................................................................................................................................................................................................................................................................................................................................................................................................MSLHQFLLEPITCHAWNRDRTQIALSPNNEVHIYKKNGSQHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQKDGVPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFEAEN-------DWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVEFGGSGTGGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLKTEFLPLLSVSFVSENSVVAA-GHDCCPMLFIYDDRGCLTFVSKLDIPKQSIQRNMSAMERFRNMDKRAT---TEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKTLESSIQGLRIM...................................................................................................................................................................................... 370
62 -54.300[R] KOG2321 WD40 repeat protein  ali follow..  10  3.........................................................................................................................................................................................................................................................................................................................LKVQNPNNVRVYTVSGEGVTQRLPNWISKRKLKKDYALSHRIELLQDFEYPEASNRIKCTRDGKYAMATGVYKPHIKVFDFA--------EMSLKFERHTDAENVQFEILSDDWTKSVHLQTDTVDFHSQGGIHYSTRIP-KYGRDLKYHYPNCDLYLAAAGDEVYRLNLEQGRFLNPLKSPTGGVNVIDINPMHQLLAFGTDAGSVEFWDPRDRSRVGILEIPSTVPSTPYSDNSRSVTALKYRNDGLNVAIGLSDGATLLYDLRSSSPYMSDQGYSMPIKSLHWMDDGTARVLSADSKIIKIWEKDTGKPFSSI-EPTVELNDVCPIEGTGLILTANEGSPMHAFYIPSLNPAPRWCSFDNITEEMEENPDDYKFVTKKELLNLGLDHLVGTGVIRA-HGFFIDNNLYEKA----RLIANPFSYEEHRQKIVKERLEKQRASKIRSQNRPKVNAGLASRLSYQENKLR--------------------------------KKTGVTDGPSILEDERFKNVFT------DKEFEVD------------------EDTLEYKQLHPSRSEARGLTAAEESEEEKEHTKGIKFSSDEESLSDMEEENETFDALVDRRKTEQQVSN...... 575
63 -53.600[T] KOG1354 Serine/threonine protein phosphatase 2A, regulatory subunit  ali follow..  1....................................................................................................................................................................MAGAGGGNDIQWCFQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQS------HSRGEYNVYSTFQSHEPEFDYLKSL-----------------EIEEKINKIRWLPQKNQFLLSTNDKTIKLWKI--SERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPM----------------------------------------------------DLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNI--------------------------------VDIKPANMEELTEVITAAEFHPNSNTFVYSSSKGTIRLCDMRASALCDRHEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRD-YLSVKIWDLMENRPVETYQVHEYDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLD----------FNKKILHTAWHPKENIIAVATTNN-LYIFQDKVN............................................................................................................................................................................................................................................ 447
64 -52.600[A] KOG0647 mRNA export protein (contains WD40 repeats)  ali follow..  16  2.................................................................................................................................................................................................................................................................................................................................................................................SFFNRSNT-TSALGTSTAMANEKDLANDIVI----------NSPAEDSISDIAFSPQQDFMFSASDGKVRIWDVQNGVPQGRASSSPVLCTRWSNDGTKVASGGCDNALKLYDIASGQ-TQQIGMHSAPIKVLRFPSNTECIVTGSWDKTIKYWDMRQPQPVST------------VMMPERVYSMDNKQSLLVVATAERHIAIINLANPTTIFKATTSPLKWQTRCVACYNEADGYAIGSVEGRCSIRYIDDGMQKKSGQSLVYPVNSIAFHPLYGTFVTAGGDGTFNFWDKNQRHRLKGYPTLQASIPVCSFNRNGSVFAYALSYDWHQGHMGNRPDYPNVIRLHATTDEEVKEKKKR...................................................................................................................................................................................................................... 365
65 -52.400[U] KOG0277 Peroxisomal targeting signal type 2 receptor  ali follow..  17  1...............................................................................................................................................................................................................................................................................................................................................................................................................MSAVCGGAARMLRTPGRHGYAAEFSPLPGRLACATAQTLLILDPDEAGLRLFRWNDGLFDVTWSENNEHLITCSGDGSLQLWDTAKAGPLQVYKEHAQEVYSVDWSQTRGLVVSGSWDQTVKLWDPTVGKSLCT-----------FRGHESIIYSTIWSPIPGCFASASGDQTLRIWDVKAAGVRIVIPAHQAEILSCDWCKNENLLVTGAVDCSLRGWDLRNRQPVFELLGHTYAIRRVKFSPHASVLASCSYDFTVRFWNFSKDSLLETVEHHTEFTCGLDFSLQSPQVADCSWDETIKIYDPACLTIP......................................................................................................................................................................................................................................... 322
66 -51.800[U] KOG0771 Prolactin regulatory element-binding protein/Protein transport protein SEC12p  ali follow..  12  1........................................................................................................................................................................................................................................................................MASNQQPPSNLQTYGVPIYAVDWILEEAVRSKITKDQDDDDDDGSSSSSYIVLSGGGGEGRS---------------------------------------------------------GIPNVILICRVDLHTN--SLSEQPIGRRVIGTDLPYRMAIHPRQGGLICALPNSCRLFDWENIIEDDNEDVGQQLSLSFNQDGTVLATGAEDGTLRVFEWPSMKTLLNESKTHASVKSLTFSESGKFLVSLG-APLCRVWDVNASAAIASLSK----------EKDEMFASCRFSVDNSVAANTQRGGSIITWDTTSWRRRSSLIKRNNSISAFNVSADGKLLAVGTLEGDVLIIDSTKMQTNQIVKAHLGLVTALTFSPDSRCLVSVSFDSRARLTVIKQKGEKRRVLWVAALLFVLVYVVLYYLMVAMGII....................................................................................................................................................................................................................................................... 382
67 -51.400[BL] KOG1009 Chromatin assembly complex 1 subunit B/CAC2 (contains WD40 repeats)  ali follow..  14  4.......................................................ITCEIAWHNKEPVYSLDFQHGTARLASAGVDTNVRIWKVEKGEFLSNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKVNDNTVVKTLRGHLEDVYDICWATDGNLMASASVDNTAIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYVATLSCDRVLRVYSIQKKRVA--------FNVSKMLSGIGAEGEARSYRMFHDD-----------------SMKSFFRRLSFTPDGSLLLTPAGCVESGENVMNTTYVFSR-------------------------------------------------------------------------------------KNLKRPIAHLPCPGKATLAVRCCPVYFELRPVVET--------------------GVELMSLPYRLVFAVASEDSVLLYDTQQSFPFGYVSNIHYHTLSDISWSSDGAFLAISSTDGYCSFVTFEKDELGIPLK-------------EKPVLNMRTPDTAKKTKSQTHRGSSPGPRPVEGTPASRTQDPSSPGTTPPQARQAPAPTVIRDPPSI........................................................................................................................................................................................................................................................................................................................................ 452
68 -50.700[Z] KOG0313 Microtubule binding protein YTM1 (contains WD40 repeats)  ali follow..  17  5.....................................................................QTRFYTDNKKYAVDDVPAASEIADL-SNIINKLLKDKNEFHKHVEFLIKGQFLRMPLDK-EIEYVEKCTAPQPEQCMFHDDWISSIKGAEEW--ILTGSYDKTSRIWSLE-GKSIMTIVGHTDVVKDVAWVKKDSLLLSASMDQTILLWEWNVERNK------------------------------------------VKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQL--------------------------------------------------------------------GLTRTPIVTLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVGSGSLKSTL-----------------------------------------TGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDG--------SLVSLSLTSHTGWVTSVKWSPTHQQLISGSLDNIVKLWDTRSCKALYDLAAHEDKVLSVDWTDTGL-LLSGGADNKLYSYRYSPTT............................................................................................................................................................................................................................................................................................................................... 418
69 -50.400[D] KOG1036 Mitotic spindle checkpoint protein BUB3, WD repeat superfamily  ali follow..  16  4.................................................................................................................................................................................................................................................................................................................................................................................................................VTPSAGRELSNPPSDGISNLRFSNNSDHLLVSSDKRVRLYDVSTNSLKGEFHGGAVLDCCFHDDFSGFSVGA-DYKVRRIVFNVGK-EDILGTHDKAVRCCLFCDVTGQVITGSWDKTVKCWDPRGASGPERTQ---------VGTYLQPERVYSMSLVGHRLVVATAGRHVNIYDLRNMSEQRRESSLKYQTRCVRCYPNGTGYALSSVEGRVAMEFFDLSEKSEAGRDIVYPVNSIAFHPIYGTFATGGCDGFVNIWDGNNKKRLYQYSKYPTSISALSFSRDGQLLAVASSYTAIFVRSVNEIEV.......................................................................................................................................................................................................................................... 342
70 -50.400[T] COG5170 Serine/threonine protein phosphatase 2A, regulatory subunit  ali follow..  10  1..................................................................................................................................................................MDDIEDSLDQWKFAQCFGDKGDVEDITEADIISAVEFDHTGDYLATGDKGGRVVLFERNHSKKGCE-----------YKFFTEFQSHEPEFDYLKS-----------------LEIEEKINKIRWCKRTNHFLLSTNDKTIKLWKLYEKNLKVVAENNLSDSFHSPMQGPLTTPSQLRLPRLNHHDMIIAAYPRRVY---------------------------------------------------ANAHAYHINSISVNSDAETYISADDLRINLWNLSISDHSFNI--------------------------------VDIKPENMEELTEVITSAEFHPNCNHLMYSSSKGNIKLLDLRQSALCDNPCKLFQDSKSFFSEIISSISDVKFSQNGRYILSRD-YLTLKIWDVNMKAPVKTIPLHDVDKFECTFSGDDKHVLSGSYSNNFGIYPTDSSL-PGDRGQIVLQADKAAFRARKSAANNVPKLNAVKNNGSASVGLDPDNLDYNKKILHASWHPFEDSVAIAATNN-LFVFS................................................................................................................................................................................................................................................ 461
71 -50.200[S] KOG0294 WD40 repeat-containing protein  ali follow..  12  2..........................................................................PPEMEIIEATNEELLLGFKLIKSELKQTFADSSYARSITSLAVQWPWVASGGTDGRIFVYDMRTRKQSQIILSHAGRVNTLKFTPDLSLLLSGSDDGHMIATRVGSWTKEYDWQKAHA--------------------------------------------------------------------------------------GQAVTHVSCHPSSKLALSLGGDQVLNTWNLVNGCVAHKTNLK-----------------------------------------------------------------------------------------NKATLDFQTGCLSWSKQGDHFTLSGPLVLEIWGIENAHVMRRIEMPSKPICITWLDGNECLTGLDNGNIAWISLKDEDPPTFILAHEVRVKAIAY--LNEFLATVSIAGQIKVWKIDMETRKLEEIARSFM--------DCRPTDLGLLDLRQFGNVRPVEQRTKVEEKPKAKV-SAKPAAPRGFVTIEYEQDKKLDAEKKKEKKKNKKDEESSESNSSEDKENDDFSDSDSDVSSDHGHRKRKPMKREQQPTPASKGKAKQQKKK............................................................................................................................................................................................................................................................................ 434
72 -50.200[S] KOG4328 WD40 protein  ali follow..  10  1..........................................................................................MATEYERKRLENIRRNDEMLAALNVRAKASSLLSAAKRS--------RDDSKSFKKKKPKPASTPTVIRMSLRTRGLNPDS-----AGLPDGFSDFRMGSQITHNQPSPQKQSPRLLAPIPFESAYEGYGSYTQLVDTLLGIESKSCRGKLVKGEIGVVKDENESPMVRTRSSS----RVSKVSVKKEEPEDDSFSDYVNKEFSIPVKPEKIEFDLDLLTLEPQNVARVVPGRIFVVQFLPCE------------------------------------------NVKMVAAGDKLGNVGFWNLDCGNEE---DNDGIYLFTPHSAPVSSIVFQQNSRVISSSYDGLIRLMDVEKSVFDLVYTDEAIFSLSQRPNDQSLYFGQDYGVFNVWDLRAGKSVFHWELHERRINSIDFNPQNPVMATSSTDGTACLWDLRSMGAKKP-------KTLSTVNHSRAVHSAYFSPSGLSLATTSLDNYIGVLSGANFENTCMIYHNNTSKFKAVWGWDDSYIYVGNLSKKIDVINPKLKRTVMELHNPRAIPCRIHCHPNVGTLAGSTAGGQVYVWTTK........................................................................................................................................................................................................................................................................................ 516
73 -50.100[YU] KOG2445 Nuclear pore complex component (sc Seh1)  ali follow..  15  2.......................................................................................................................................................................................................................................................................................................................................................................................................................QPFDSGHDDLVHDVVYDFYGRHVATCSSDHIKVFKLDKDTDSWRAHDSSIVAIDWASPGRIIASASYDKTVKLWEEDPDQKLCTLNDSKGSLYSVKFAPAGLKLACLGNDGILRLYDALEPSDLRSLTSEMKVLSIPPANHLQSDFCLSWCPSRFEKLAVSALEQAIIYKDGKLHVAAKLPGHKSLIRSISWAPSYQLIATGCKDGRIRIFKITEKLSPLASEESLTNSNMFDNSADVDMDAQGRSDSNTELQSNLQVELLSEHDDHNGEVWSVSWNLTGTILSSAGDDGKVRLWKATYSN-VITAQQ.................................................................................................................................................................................................................................... 349
74 -49.900[R] COG2319 FOG: WD40 repeat  ali follow..  11  105.................................................................................................................................................................................................................................................................................SLSRNLVNKTKNASETYQQLLEYAEVERDDNVFTYAKLQKSDM----TQKCPTMVASEKDNKGKLNEKKNRSPENLLPF----------------------------------------------------RILDAPELRDDFYTSLLSWSPKGDLAIGLA-ENIYLWSKELGPTRVL-SIYDVSSVAYSYNGDILAVGRVDGTLQFWQDNERV-PRISIHHPGDIGVLAWKPETNRLLVGKGNGNIFVYDIIWSESTSKAVLVA----TITNAHDEQVCGLTWNHDGSQFASGGNDNRVCLFKGSDLRQPLYVWQQNAAVKALSFCPWQRSLLAGSHDKHIRFYNCFNGKKIDELYCGAQ-ITSIHWSPKYREFSVTTVQHRFAVYSWPQLECLVSVLPPDIRCVHSVLTSQTDSIIIASSNETIKFFDLSEESSWLTWHGIFDSQILEMLEG-------IDGKIDSHLR....................................................................................................................................................................................................... 535
75 -49.900[R] KOG0322 G-protein beta subunit-like protein GNB1L, contains WD repeats  ali follow..  10  1...............................................................................................................................................................................................................................................................................................................................................................................................................MAVLPPDPVFSLRSPDGAVNSLCFQESDRLLAGTIKGSVFLWDLQTNRSALHFEVGSDPITSLHHTPDRLVTQEKGGTITMFSIGGSSYVKELGFCRSALHTNTSKTNEQLLFYPCEESSIGVLHVTDAAAPTQILVPDDPQLPKL--GSVTCFKPFECASQLFLLAGYESGHFLTWDISSSVIL-DVMELAQDATSVDYDPVTNRGIVGGPTDKLISFSYQRSQLGSELCIKNPGVNGVRIRPDQKVFASAGWDGRIRIFSWKSLRPLAVLTQHNGGVMDLAFSSQAPIMAAAGMDGQISLWDLYN............................................................................................................................................................................................................................................. 323

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zhao Y, Hong DH, Pawlyk B, Yue G, Adamian M, Grynberg M, Godzik A., Li T. The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesis. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3965-70. Epub 2003 Mar 21.