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Query: [O] KOG0448 Mitofusin 1 GTPase, involved in mitochondrila biogenesis, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAEPVSPLKHFVLAKKGITAIFDQLLEFVTEGSHFVEATYKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEWLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVANALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVNLAAEDKRHYSVEEREDQIDRLDFIRNQMNLLTLDVKKKIKEVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPNPDVLKIYKSELNKHIEDGMGRNLADRCTDEVNALVLQTQQEIIENLKPLLPAGIQDKLHTLIPCKKFDLSYNLNYHKLCSDFQEDIVFRFSLGWSSLVHRFLGPRNAQRVLLGLSEPIFQLPRSLASTPTAPTTPATPDNASQEELMITLVTGLASVTSRTSMGIIIVGGVIWKTIGWKLLSVSLTMYGALYLYERLSWTTHAKERAFKQQFVNYATEKLRMIVSSTSANCSHQVKQQIATTFARLCQQVDITQKQLEEEIARLPKEIDQLEKIQNNSKLLRNKAVQLENELENFTKQFLPSSNEESLast
1 -146.000[O] KOG0448 Mitofusin 1 GTPase, involved in mitochondrila biogenesis  ali  100  1MAEPVSPLKHFVLAKKGITAIFDQLLEFVTEGSHFVEATYKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEWLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVANALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVNLAAEDKRHYSVEEREDQIDRLDFIRNQMNLLTLDVKKKIKEVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPNPDVLKIYKSELNKHIEDGMGRNLADRCTDEVNALVLQTQQEIIENLKPLLPAGIQDKLHTLIPCKKFDLSYNLNYHKLCSDFQEDIVFRFSLGWSSLVHRFLGPRNAQRVLLGLSEPIFQLPRSLASTPTAPTTPATPDNASQEELMITLVTGLASVTSRTSMGIIIVGGVIWKTIGWKLLSVSLTMYGALYLYERLSWTTHAKERAFKQQFVNYATEKLRMIVSSTSANCSHQVKQQIATTFARLCQQVDITQKQLEEEIARLPKEIDQLEKIQNNSKLLRNKAVQLENELENFTKQFLPSSNEES 741
2 -26.900[R] COG3596 Predicted GTPase  ali follow..  10  5.........................................NFEVLQPLQNSLSGLPLWVSERILQQINQLTHYEPVIGIMGKTGAGKSSLCNALFAGEVSPVSDVAACT----------------------------------------------------LRFRLQIGEHFMTIVDLPGVGESGVRDALYREQLPRLDLILWLIKADDRALATDEHFYRQVIGEAYRHKMLFVISQSDKAEPTSGGNILSTEQKQN------RKICLLHELFQPVHPVCAVSVRLQ--------------------------WGLRVMAERMIKCLPREPSSPVVALLQHPFRTAREQARDDFGETVDTILDTVSTFPLIPAPVRTIIQAVRSSVVSVARAVWDFF....................................................................................................................................................................................................................................................................................................................................................... 288
3 -24.700[TU] KOG1954 Endocytosis/signaling protein EHD1  ali follow..  14  9.PRANRNEITFYPDYEEEGQKKKKTRSMFSWLGGDSSKKKNKEVLETVSEGLRKI----YKQKLLPLEEFHKFHDFHILLVGQYSTGKTTFIRYLLESDFIRIGPEPTTDRFIAVMHGDEEGSI-----VDAKKQFRALSGFGNAFLN----------RFQCSTLPNQVLES-VTIVDTPGILSGEKQTGVLEWFAERVDRIILLFDAHKLDISDEFKRCIEALAGNE-DKIRIVLNKSDMVDHQQ----------LMRVYGALMWSLGKVFKTPEVSRVYLGS......................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 290
4 -20.700[R] COG0699 Predicted GTPases (dynamin-related)  ali follow..  10  217....................................EDTLTADEKRKLAQESKEDRMMLFTKKMIEIRNILQD---SIVVIGSQSSGKSSVLEAIVGHEFLPKGSNMVTPIELTLVHSADTAIPYGEFSGVQLGKITDFSKIQHILTDLNMDDNPIRLTIYASHIP------NLSLIDLPGYDLDMKISKLCEKYIREPNIILAVCAADVDLANSAALRASRRVDPLGLRTIGVVTK--DLVPPSKAISILHNNNYPLHYGYIGVISRIVPTGRFS-------AGQNLTDLVSTQENSYFSTHQQFADARIGNYLGIQSLRKCLINVLE-YTMSKNLQHTADSIRTELEECNYQYKVQNDRVLTADSYIAEGLDIFKAAFKEFTQKFSEVRDLLKSSLNEKVMDLLAERYWTDDDISNWSKHTNALDEHWKYKLDSCVSTLTRM-TLLVTDSISKCIDEITKASPFADHPAAMQYIMNAAQDILRRRFHATSEQVENCVKPYKYDVEVNDDEWKSSRGQAEKLLQRELGLCQSALEKIKNAVGSRRMNQVLQYLEEQKTSSEPLPASYSTALLEQGRMLQYLKMREDILKLRISVLKS-----------------------------KEAKYTCPEIFLNAVSDKLVNTAVLFINELLSEFYYQFPRELDQRLIHSLSS--EQLNAFVNENPKSQLQLQHKRQCLELALQKINSLVILEQQADSD................ 903
5 -19.600[E] COG4917 Ethanolamine utilization protein  ali follow..  13  3............................................................................RIAFVGSVGAGKTTLFNALQGNYT-------------------------------------------------------------LARKTQAVEFNDKGDIDTPGE-NHPRWYHALITTLQDVDMLIYVHGANDPESRLPAGLLDIGVSK----RQIAVISKTDMPDADVAATRKLLLET-------------------FEEPMFELNSHDP--------------------------QSVQQLVDYLASLTKQEEAGEK..................................................................................................................................................................................................................................................................................................................................................................................................................... 154
6 -18.800[UR] KOG0446 Vacuolar sorting protein VPS1, dynamin, and related proteins  ali follow..  13  1.......................................MSVDDLPPSSASAVTPLGSSVIPIVNKLQDIFAQ---QVAVVGSQSSGKSSVLEALVGRDFLPRGNDICTPLRLQLVQTKPSSDGGSDEEWGEFLHHDPVRRIYDFSEIRREIEASDIPIGLKIFSP----VLDISLVDLPGIDIEARIRTMILTYIKEPSCLILVSPANTDLANSDALQIAGNADPDGHRTIGVITK--DIMDRGTDARNHLLGKTVNRSQEDILMNRSIKDALVAEEKFFRSRPVYSGLTDR----------------------GVPQLAKKLNQVLVQH------------IKALLPSLKSRINNALFATAKEYESYGDITESRGGQGALLLSFITKYCEAYSSTLE...................................................................................................................................................................................................................................................................................................................................................... 365
7 -18.700[R] KOG2486 Predicted GTPase  ali follow..  11  119..........................................................DYVKSSVKTEDCPADGLPEFALVGRSNVGKSSLLNSLVRRKLALTSKKPGKT---------------------------------------------QCINHFR-------INDKWYLVDLPGYGLKQDWNKFTKDYFSTLVSVFLLVDASIPVKPIDLEYASWLGQNQ----MTLIFTKCDKRKKKKNG-----GKKPEANIKEFQDLIQGFFETTPP--WIMTSSVTN..................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 298
8 -17.500[R] COG1084 Predicted GTPase  ali follow..  12  84VDELKKSLGALNWAVGILNQLESDYMARIKRSKPSDASHLRREAFGRISSVIKRIEGDDFAKNKLRNMPTVDLDAFTVVIAGFPNVGKSTLLRTLTGAEPEVADYPFTTIQIGHLERKWKR----------------------------------------------------IQVIDTPGLDMNNIELQAMVALENIADVIMFIFDASETCGYTLESQYSLYLGIRSVIPVVTVFNKMDLAENVKYLEEYINM-----------------------EDPLKVSAFEG--------------------------RGVSKIIKKLEGLYEKETREAHDN................................................................................................................................................................................................................................................................................................................................................................................................................... 335
9 -16.700[J] KOG1191 Mitochondrial GTPase  ali follow..  12  291..............SSLVKSLRAQCIELLTEIEARLD----EDEMPPLDIESVINKITSMSQDVESALDKLLQSGLQIAIVGRPNVGKSSLLNAWSKSEAIVTEVAGTTRDVVE----------------------------------------------------ANVTVRGITLLDTAGIRETNDIVEKSETAAKVADVIIMAVSAVEGWTEEDTELLRKIQSDKLKQPMILVMNKIDCAPPGSCDQLEDQRKK-----------------EEVFHKSVFTSAVTLGLDRVPTGGHQWTVNQRQCEQLVRTKEALVRLREAIEDEIPIDFWTIELREAALSLAQISGQD...................................................................................................................................................................................................................................................................................................................................................................................................... 596
10 -16.400[R] KOG2203 GTP-binding protein  ali follow..  10  11..............................................QLIDGNGEFNVKGLDNFVKKTKLSDCGLSYAVVIMGPQSSGKSTLLNHLFKTSF--AGRSQTTKGI------------------------------------------------------CVGIEPFTIAMDLEGTDGRERGED---DTTFEKQSALFAIAVADIVQAANKPLLKTVFQSPRKTTLLFVIR--DKTKTPIELLERALREDIQKIWDSVRKPEAHKNTPLNE--FFNVMEQEVAELRQRFFHSISPGGLAGDRRGVVPASGFSFSSQQIWKVIKENR-AHKVMVATVRCEEIANEKLRDLATNESWLELHEAAEGGLVPGFGKKLSSILEKYKEKRLQLKLNALDFVYPSATMLGHLRSNALESFKIRLEQSLNQGEGFAKAVRDSQQSCLMVFDKGCEDAAVKQATWDASKIREKLCRDIDAHTFFARSAKLSELTANYEKRLTQALSEPVE......................................................................................................................................................................................................................................... 473
11 -15.800[R] COG1159 GTPase  ali follow..  13  11.............................................................................IAIVGRPNVGKSTLLNKLLGQKISITSRKAQTT-IVGIHTEGPYQ---------------------------------------------------AIYVDTPGLHMEEKMNKAASSSIGDVELVIFVVEGTRW-TPDDEMVLNKLRDG--KAPVILAVNKVDNVQEKVD----------------LLPHLQFLASQMNFLDIVPISAETG--------------------------MNVDTIAGIVRKHLPEAIHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVTNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEA........................................................................................................................................................................................................................................................................................................................... 271
12 -15.700[DZ] COG5019 Septin family protein  ali follow..  78...............................................................FASLPNQWHRRNFNVLVLGESGSGKSTLVNTLLNRDVYPPTQKSLTG------------------------------------DFGVNPEPTVMINSSAVEIVENGISLQLNVIDTPGFGDFIDNTD-VLTDIERVHACIFFIQTGHAISAMELRVMLALHEKVNI--IPIIAKADTLTDDELNFTKEMILRDIQY--TDDPESVAENADIMSRIPFAIIASNTFVVNNEGKRVRGRRYPWGVVEVDNEEHSDFPKLREML------------IRTHLEELKEQTNKLYEAYRTERLSSGISQDHSVFREVNPSAKLEEERALHEEKLMKMEAEMKTIFSQKVQEKEDRLKQSENELRTRHREMKAALEKQKADLIDHKNRLMQAKAAAENEKSKRKFFK...................................................................................................................................................................................................................................................................................... 469
13 -15.600[R] COG0218 Predicted GTPase  ali follow..  14  9..........................................................EILLSAANKSHYPQDELPEIALAGRSNVGKSSFINTMLNRKNLATSGKP-TQLLNFFN-----------------------------------------------------IDDKMRFVDVPGYGEREKWGCMIEEYLTTREAVVSLVDLRHDPSADDVQMY-EFLKYYEIPVIIVATKADKIPRGKWNKHESAIKKKLN---------------FDPSDDFILFSSVS...................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 180
14 -15.300[R] COG1160 Predicted GTPases  ali follow..  13  141.....EIEQIAASQGRGVTQLMEQVLAPFAEKMENADENDRTSEEEQDEWEQEFDFDSEEDTALIDDLEEEQDKNIKIAIVGRPNVGKSTLTNRILGEDVVVFDMPGTTR--------DSIYIPMERDGQQ------------------------------------------YTLIDTAGVRKRGKVHLAVEKFIQDANVVLLTIDARENISDQDLSLLGFILNAG--RSLVIVVNKWDGLDQDVKDR--------------VKSELDRRLDFIDFARVHFISALHG--------------------------SGVGNLFDSIKEAYACATQKMTTSLLTRILQMATDEHQPPMIGGRRIKLKYAHPGGYNPPIIVVHGNQMDKLPDSYKRYLSNYYRKSLKIIGSPIRLLFQEGSNPFAGRKNKLTPNQLRKRKRLMKFIKKAKR...................................................................................................................................................................................................................................................................................................... 504
15 -14.600[R] COG0486 Predicted GTPase  ali follow..  15  164..............SNKVNQLVDSVIYLRTYVEAAID----DEEIDFLADGKIEAHLNDIITQLDHVRSSILREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTT---------------------------------------------------VLREHIHIDGMPLHIIDTAGLREATDEVERAWSEIEQADRILLMLDSTEADNQDLEKVRSEFLTKLPSNIVTIVRNKADLSGENEGIVEQ------------------------NGYTVITLSAKTQ--------------------------QGIALLREHLKQSMGYQTNMEGGFLARRRHLEALEQAATHLQQGHVQLTQAGELLAEELRRVQNHLSEITGQFTS................................................................................................................................................................................................................................................................................................................................................................ 450
16 -13.700[J] KOG0468 U5 snRNP-specific protein  ali follow..  10  61LHEDKRYYPSAVEVYGPDVETIVQEEDAQPLDKPLIEPVKKLKFQIKEQDMQETTYDMEFMADLMDTPPLIRN----VALVGHLHHGKTTFVDCLIRQ----------THPQFETMEERQLRYTDTLFTEQERGCSIKATPVTLVLQDVKQKS--------------------LNIFDTPG-----NFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQERQAITVCI--NKIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTYGAPDDNLLVSPILGNVCFASSLYGFCFTLKS--AKLYADTYEGVAYLDFAKRLWGDMYFNSKTRKFSKKQPHNSAQRSFVEFILEPMYKLIAQVVGDVDTTLSDTLAELN-VRVSKEEMKSNIRPLLRLVCNRFMGDCSGFVDMCVEHIKS............................................................................................................................................................................................................................................................................................................................... 443
17 -13.600[U] KOG0090 Signal recognition particle receptor, beta subunit (small G protein superfamily)  ali follow..  13  52.......................................................................RTKSNTVLLSGLSGSGKTVLFYQLRDGSSHQGAVTSMEPNEGTFVLHNENNTK----------------------------------------------VKPVHLIDVPG---HSRLISKLEEYLPRAAAVVFVVDALEFLPNIRADILTNASVIKNKTPVLLCCNKTDKVTATKEFIRKQMEKEIDKL................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 201
18 -13.500[R] KOG1490 GTP-binding protein CRFG/NOG1 (ODN superfamily)  ali follow..  13  95......ALGQVNTARNLISKISKDYVKLLKYGDSLYRCKCLKVA-RITPSLAYLEQIRQHMARLPSIDPNTRT----VLICGYPNVGKSSFMNKVTRADVQPYAFTTKSLFVGHTDYKYLR----------------------------------------------------YQVIDTPGINIIEMCSITALAHLRAAVLFFLDISGSCGYTAQQAALFHSIKSLFMNKPLVIVCNKTDLMPMEN-----ISEEDRKLIEEMKSEAMKTAMGASEEQVLLKMSTLTD--------------------------EGVMSVKNAACERLLDQRVEAKMKS.................................................................................................................................................................................................................................................................................................................................................................................................................. 360
19 -13.400[R] COG2229 Predicted GTPase  ali follow..  13  2.........................................................................RENKIIFTGPVGVGKTTAIAAISDEALVQTDASASDMTL-----DRKRNTTVAMDYGAISLDEDTK----------------------------------VHLYGTPG---QERFNFMWEILSQGSMGLVLLLDNARTNPLKDLEFLHSFRGLLEKAPVVVGITKMDIRSQPGIDVYHKYLAKHNLNVP-----------------VFEIDARKEDDVKQ................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 163
20 -13.400[J] KOG0469 Elongation factor 2  ali follow..  11  7..........................................................DEIRALMDRKRNIRN----MSVIAHVDHGKSTLTDSLVSKAGIIAGSKAGETRFTDTRKDEQERISLFFELEKKDLEFVKGENQFETVEVDGKKEKYNGFL--------------INLIDSPG-----DFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLFM--NKMDRALLELQLGAEELFQTFQRIVENINVIIATYGDDDGPMGPIMVD---PSIGNVGFGSGLHGWAFTLKQFAEMYAGKFGVQVDKLMKNLWGDRLKTKKWSSTQTDESKRGFCQFVLDPIFMVFDAVMNIKKDKTAALVEKLG-IKLANDEKDLEGKPLMKVFMRKWLPAGDTMLQMIAFHLPSPVT............................................................................................................................................................................................................................................................................................................................ 357
21 -13.200[DTZ] KOG1547 Septin CDC10 and related P-loop GTPases  ali follow..  12  263...............................................................IDSILEQMRRKEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSE--------------------ERIPKTIEIKSITHDIEEKG-------------------VRMKLTVIDTPGFGDHINNEN-IMKFINRVHCCLYFIPTGHSLRPLDIEFMKRL---SKVVNIVPVIAKADTLTLE--ERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLL------------IRTHMQNIKDITSSIHFE-AYRVKRLNEGSSAMANGVEEKEPEAPEM...................................................................................................................................................................................................................................................................................................................................................................... 568
22 -13.200[P] COG2895 GTPases - Sulfate adenylate transferase subunit 1  ali follow..  12  1................................................MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHD----------TRQI------YEDQLSSLHNDSKRHGTQGEKLDLALLVDGQAEREQGITIDVAYRYFSTE--KRKFIIADTPG------HEQYTRNMASTCELAILLIDARKGVLDQTRRHS--ISTLLGIKHLVVAINKMDLVDYSEETFTRIRED---------YLTFAGQLPGNLDIRFVPLSALEG..................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 210
23 -13.000[J] KOG0466 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  13  25............................................................VTKLTPLSHEVRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYQLDDPSCPRPECYRSCGSSMPDEFPTDIPGTKGNFR-----------VRHVSFVDCPG------HDILMATMLNGADAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKERQ---AKEQYEQILAFVQ---------GTVAEGAPIIPISAQLK..................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 229
24 -12.900[P] COG0370 Fe2+ transport system protein B  ali follow..  11  2.........................................................................SQNTYCILGNPNTGKTSLFNALTGSY----------------YVGNWSGVTVEKKVGT-------------------------------------LRSKTGKLIDLPGLNPISRDETVVTRFLEKFDCMLNIVDSSQ-----ERNLNLTVQLLEYGAPVVMGLNMIDVAAGRGIHLNIQNLAKKLRI------------------PILPVVARSGKGTEDILSTLSEKHVAPAIPLVLQYGEPAEKAIKEIQALTKELIPAKQSRWLAIQFLSKNEVTEAFLTSNSAFEQLQQIRAELESELNGKLENHFHQVRASYIHDICLTSVEYTRNSDIPLSDKLDKIFTH.................................................................................................................................................................................................................................................................................................................................. 278
25 -12.900[R] KOG1673 Ras GTPases  ali follow..  14  102...........................................................................LKISLLGDCQTGKTTFVVKYVGDEN--QSFLEMTGL-------NLMDKTFYVQGVTIS----------------------------------------FSIWDVGG--DEKRSKDHIPIACKDAVAILFMFDLTSRSTLNSFGWYSQARKWNKTAIPILIGTKFDDFVRLPPNLQWTIVTQARAYAK------------VMNASLFFSSATHNINVNK................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 257
26 -12.900[DZU] KOG2655 Septin family protein (P-loop GTPase)  ali follow..  10  18...............................................................FANLPNQVHRKEFTLMVVGESGLGKSTLVNSLFLTDLYPERIIPDAI---------------------------------------EKQKQTVKLEASTVEIEERGVKLRLTVVDTPGFGDAIDNSGAILEYIDRIHCCFYFISFGHGLKPLDVEFMKKLHSKVNI--VPVIAKADCLTKKEILRLKCRIMQEIES--SDEDEDYKEQVKQLKEAVPFAVCGANTLLEVKGKKVRGRLYPWGVVEVENPDHCDFIKLRTMLITHMQDLQEVTQEVHYENYRSDRLAKGIK--GKENGVKAERDSSSQVVSNSVLGEKDRILQEKEAELRRMQEMLAQMQARMQAQ............................................................................................................................................................................................................................................................................................................................................. 360
27 -12.700[T] KOG3886 GTP-binding protein  ali follow..  10  1...................................MEESDSEKTTEKENLGPRMDPPLGEPEGSLGWVLPNTAMKKKVLLMGKSGSGKTSMRSIIF-ANYIARDTRRLGATI-----LDRIHSLQINSSLSTYSLVDSVGNTKTFDVEHSHVRFLGNLV--------------LNLWDCGGQDTFMENTSQRDNIFRNVEVLIYVFDVESRELEKDMHYLEAILQNSPDAKIFCLVHKMDLVQEDQRD------LIFKEREEDLRRLSRPLECSCFRTSIWDETLYKAWSSIVYQ----------NVQQLEMNLRNFAEIIEADEVLLFERATFLVISHYQCKEQEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFTSNTYVMVVVSDPSIPSAATLINRNARKHFEKLER................................................................................................................................................................................................................................................................................................................................... 363
28 -12.700[T] COG1217 Predicted membrane GTPase involved in stress response  ali follow..  13  1..................................................................MIENLRN----IAIIAHVDHGKTTLVDKLL------------SGTLDRKEAESER------------------------VMDSNDQEKERGITILAKNTAIKWNGYNINIVDTPG---HADFGGEVERVMSMVDSVLLVVDAQDGP-MPQTRFVTQKAFKAGLRPIVVV-NKIDRPGARPDWVIDQIFDLFDNL................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 151
29 -12.700[R] KOG0410 Predicted GTP binding protein  ali follow..  12  214CDRTALILDIFNQAATHEAALQVALAQMEYQLPRLTRMWTHLER--EVDKRILRTQIGVLKKELESVSRRVAIPVPVVSLVGYTNAGKSTLLNQLTGANVLAENRLFAT---------DPTTRRVQMQNGKE-----------------------------------------FLLTDTVGFTTLVAAFRATLEEIAESSLLVHVVDISHPLAEQQIEAVEKVMSELDVSSKLVVWNKVDRVDDPQKVKLEAEET----------------------GDTICISALTG--------------------------EGLDDFCNAVHEKLKDSMVWVEALLPFDKGDLL.......................................................................................................................................................................................................................................................................................................................................................................................................... 491
30 -12.500[D] KOG3859 Septins (P-loop GTPases)  ali follow..  25...............................................................FDSLPDQLVNKCFNILCVGETGLGKSTLMDTLFNTKFEG--------------------------------------------EPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSIVEFIDA--CLYFIAPTGHSLKSLDLVTMKKLD---SKVNIIPIIAKADAISKS--ELTKFKIKITSELVSNGVQIYQFPTDDESVAEIFAVIGSTEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR--CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA-EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELPQSQGSQAGGSQTLKRDKEKK.......................................................................................................................................................................................................................................................................... 426
31 -12.300[U] KOG3887 Predicted small GTPase involved in nuclear protein import  ali follow..  10  59.......................................................................TEVKPRILLMGLRRSGKSSIQKVVF-HKMSPNETLFLESTN-----------------------------------CREDVSNSSFVN--------------FQIWDFPGQIDFFDPTFDYEMIFRGTGALIFVIDSQDDYMEALARLVTRAYKVNTDINFEVFIHKVDGLSDDHKI------ETQRDIHQRANDDLADAGLEKIHLSFYLTSIYD--HSIFEAFSKVVQKLIPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSTPVDELCCDMIDVVIDISCIYGLKEDGAGTPYDKESTAIIKLNNTTVLYLKEVTKFL....................................................................................................................................................................................................................................................................................................................................................... 336
32 -12.200[J] KOG0458 Elongation factor 1 alpha  ali follow..  16  164.......................................................................ALPHLSFVVLGHVDAGKSTLMGRLL------------------YDLNIVNQSQLRKLQRESETMGKSSFKFAWIMDQNEERERGVTVSICTSHFSTH--RANFTIVDAPG------HRDFVPNAISQADMAILCVDCST--NAFESGFDLDLASSLGIHNLIIAMNKMDNVD--------WSQQRFEEIKSKLLPYLVDIGFFEDNINWVPISGFSG..................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 356
33 -11.800[J] KOG0462 Elongation factor-type GTP-binding protein  ali follow..  13  40....................................................................DKIRN----FGIVAHVDHGKSTLADRLL----------EMCGAV---------------------------PPGQKQMLDKLQVERERGITVKAQTAALRHRGYLLNLIDTPG---HVDFSAEVSRSLAVCDGILLLVAANQGVQAQTIANFWLAFEKN---QIIPVINKIDLPGADIKSVETQLKN...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 180
34 -11.600[J] KOG0052 Translation elongation factor EF-1 alpha/Tu  ali follow..  12  4.......................................................................EKVHINIVVIGHVDSGKSTTTGHLIYK----------CGGI-------DKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETA--KYYITIIDAPG------HRDFIKNMISQADCAVLVVACGTGEFEAGISKNGQTREHAGVKQLIVACNKMDSTEPP------FSEARFTEITNEVSGFIKKIGYNPKAVPFVPISGFNG..................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 198
35 -11.500[J] KOG0459 Polypeptide release factor 3  ali follow..  16  63....................................DEVMLHPVHNPAKAKEKAAQEKAAKEEAEDVAEANKKRHLNVVFIGHVDAGKSTIGGQILFL----------SGQV-------DDRQIQKYEKEAKDKSRESWYMAYIMDTNEEERLKGKTVEVGRAHFETE--STRFTILDAPG------HKSYVPNMISQADIGVLVISARK--GQTREHVQ--LAKTLGVSKLIVVVNKMDDPT------VNWSKERYDEIEQKMVPFLKASGYNTKKDVVFPISGLMG..................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 293
36 -11.300[R] COG1163 Predicted GTPase  ali follow..  11  1.....................MSTTVEKIKAIEDEMARTQKNKATSFHLGQLKAKLAKLRRELLTSASSG-RTGVASVGFVGFPSVGKSTLLSKLTGTEAAEYEFTTLVTVPGVIRYKGAK----------------------------------------------------IQMLDLPGIKDGRGRGKQVIAVARTCNLLFIILDVNKPLHHKQEKELEGVGIRLNKTPPDILIKKKEK.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 187
37 -11.300[R] KOG2037 Guanylate-binding protein  ali follow..  11  25.........................................................PEALKILSAITQPVV-----VAIVGLYRTGKSYLMNKLAGKK-LGSTVKSHTKGI----------------------------------------------------WCVPHPKKPVLLDTEGLGDIEKGDNENDSWIFALAILLTFVYNSMGTINQQAMDQLHYVTELTDRAFVWTLRDFTLELEVDGEPIDDYLELSLKLRKGTDKKSKSFNDPRLCIRKFFPKRKCFVFDWPAPKKYLAHLEQLKEEELNPDFIEQVAEFCSYI---LSHSNVKTLSGGIAVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIEN-----SAAVEKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFM----------KNSFKDVDQMFQRKLGAQLEARRDDFCKQNSKASSDCCMALLQDIFGPLEEDVKQGTFSKPGGYRLFTQKLQELKNKYYQVPR---GIQAKEVLKKYLESKEDVADALLQTDQSLSEKEKAIEVERIKAESAEAAKKMLEEIQ-----------------------------------------------KKNEEMMEQKEKSYQEH-VKQLTEKMERDRAQLMAEQEKTLALKLQEQERLLKEGFENESKRLQKDIWDIQMRSKSLEPICNIL............................. 591
38 -11.300[M] COG0481 Membrane GTPase LepA  ali follow..  12  2....................................................................KNIRN----FSIIAHIDHGKSTLSDRLI----------QTCGG---LSDREMEAQVLDSMDLERERGITIKAQSVTLNYKAKDGETYQ-----------------LNFIDTPG---HVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIEMN---EVVPILNKIDLPAADPERVAEEIED...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 149
39 -11.200[J] KOG0460 Mitochondrial translation elongation factor Tu  ali follow..  16  50.......................................................................KKPHVNIGTIGHVDHGKTTLTAAITK--------------------------CLSDLGQASFMDYSQIDKA------PEEKARGITISSAHVEYETA--NRHYAHVDCPG------HADYIKNMITTMDGAIIVVSATDGQMPQTREHL-LLARQVGVKQIVVYINKVDMVEPD----------MIELVEMEMRELLSEYGFDGDNTPIVSGSALCALEGREP............................................................................................................................................................................................................................................................................................................................................................................................................................................................... 224
40 -11.100[T] KOG1487 GTP-binding protein DRG1 (ODN superfamily)  ali follow..  11  1.................MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKA-----RLAKLRRELITPKGG-KTGDARIGFVGFPSVGKSTLLSNLAGVEVAAYEFTTLTTVPGVIRYKGAK----------------------------------------------------IQLLDLPGIKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKENELEGFGIRLNSKPPNIGFKKKDK.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 186
41 -11.000[V] KOG1707 Predicted Ras related/Rac-GTP binding protein  ali follow..  15  3...............................................................MGVGDSSGSPKPIRIVVVGEKGSGKSSLIMAAARNTFIPS-LLPYTNLPSEFFPDRIP----------------------------------------------------ATVIDTSS---RPEDKGKVVKEVRQADAIVLTFAFDRPLDRLSKYWLPLFRQLEVRVPIIVAGYEVDNKEAYNHFSIEQITSALMKQYREVETSIQWSAQRLDQKDVLYYAQKAVI.................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 178
42 -11.000[R] KOG0083 GTPase Rab26/Rab37, small G protein superfamily  ali follow..  18  469...........................................................................GKVIMLGDSGVGKTSLLIRFRDGRYVPSYFLSTVGI-------DFRNKVVVVDGTRVK----------------------------------------LQIWDTAG---QERFRSVTHAYYRDAHALLLLYDVTNKTTYDNRAWLGEIREYAQEDVVIVLINKADCSGSERQVKREDGERLGREH----------------NVPFMETSAKTGLNVE----------------------LSFTAVARQLKSRGYEHGDDGKFN................................................................................................................................................................................................................................................................................................................................................................................................................... 645
43 -10.900[R] KOG0395 Ras-related GTPase  ali follow..  17  17........................................................................KNSYRMVVLGASRVGKSSIVSRFLNGRFED-QYTPTI--------EDFHRKVYNIRGDMYQ----------------------------------------LDILDTSG---NHPFPAMRRLSILTGDVFILVFSLDNRESFDEKRLQKQILEVKSCLKMVICGNKNDHGELCRQVPTTEAELLVSG---------------DENCAYFEVSAKKNTN................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 178
44 -10.900[R] COG2262 GTPases  ali follow..  12  101IDRTGLILDIFAQARTHEGKLQVELAQLRHLATRLVRGWTHLERQKETDRRLLRNRIVQIQSRLERVEKRIKADVPTVSLVGYTNAGKSTLFNRITEARVYAADQLFAT---------DPTLRRIDVADVGE-----------------------------------------TVLADTVGFHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIEAVNTVLEEIDAHETLLVMNKIDMLEDFEPRIDRDEENKPIRV---------------------WLSAQTG--------------------------AGIPQLFQALTERLSGEVAQHTL.................................................................................................................................................................................................................................................................................................................................................................................................................... 370
45 -10.800[J] COG5257 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  11  3.......................................................................NQSEINIGLVGHVDHGKTTLTKALSGVWT---------------THSEETKRGISIRLGYADITFRK--------PQCEAPMCYTTAEICERCGTETELLRKVSFVDAPG------HETLMATMLSGADGAILVIAANEPCPQPQTKEHLMALDVIGVKDVIVVQNKIDIVSKERALESYREIKEFVK------------GTCAEDAPIIPVSAQQG..................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 183
46 -10.700[F] COG1618 Predicted nucleotide kinase  ali follow..  13  7.......................................................................EKTMLRIAVTGSPGVGKSTVVAKTA-EKLAEKPGFKIGGIRTAEIRKEGHREGFSIRDLATGKTGILSHVKGSGPRLGKYHVNLDDLERIGANAVRNALACDLVVIDEIGPMELISQSSAVEEVLESDKPVLAVL---------HHSSRHPLAQRFRKGFEVL-----TVDKGNRDELPEKITNRFLRKLG............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 184
47 -10.600[U] KOG0096 GTPase Ran/TC4/GSP1 (nuclear protein transport pathway), small G protein superfamily  ali follow..  12  1...............................................................MSAPAANGEVPTFKLVLVGDGGTGKTTFVKRHLTGE-FEKKYIATIGV-------EVHPLSFYTNFGEIK----------------------------------------FDVWDTAG---QEKFGGLRDGYYINAQCAIIMFDVTSRITKNVPNWHRDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKN--------------------QYYDISAKSNYN................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 158
48 -10.600[T] KOG4252 GTP-binding protein  ali follow..  18  1..................................................................MLEEDMEVAIKMVVVGNGAVGKSSMIQRYC-KGIFTKDYKKTIGVDFLER-------QIQVNDEDVR----------------------------------------LMLWDTAG---QEEFDAITKAYYRGAQACVLVFSTTDRGSEAVSSWREKVVAEVGDIPTVLVQNKIDLLDDSCIKNEEAEALAKRLRLRFYRTSVKE---DLNVNEVFKYLAEKYLQKLKQQIAE........................................................................................................................................................................................................................................................................................................................................................................................................................................................... 179
49 -10.600[OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase  ali follow..  11  1.......................................................................MKRPLIIGVGGPVGAGKTMLIERLT-RYLSTKGY--SMAAITNDIYTKEDARILLNTSVLPADRIAGVE--TGGCPHTAIREDASMNFAAIEEMCDKHPDLQLLFLESGGDN----LSATFSPDLVDFSIYIIDVAQGEKIPRKGGQGMIKS---------LFIINKVDLAPYVGANVEVMKADTLK---------------SRGNKDFFVTNLKTD..................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 185
50 -10.600[J] COG5256 Translation elongation factor EF-1alpha (GTPase)  ali follow..  15  7.......................................................................QKPHLNLITIGHVDHGKSTLVGRLLYE----------HGEI-------PAHIIEEYRKEAEQKGKATFEFAWVMDRFKEERERGVTIDLAHRKFETD--KYYFTLIDAPG------HRDFVKNMISQADAAILVISAREVMEQTREHAF--LARTLGVPQMVVAINKMDATSPP------YSEKRYNEVKADAEKLLRSIG---KDISFVPISGYKG..................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 194
51 -10.500[R] COG5258 GTPase  ali follow..  10  58......................EELVKALETLREMARRVGASLYILRVSEGIRGKVAEVLLRAVSREEPP---PTVTVVALGNVDAGKSTLVGVLTTGRL---------------DGKGLARSYASRYKHEVLTGRTSAVSLRLLGFSGDKVVNHGLIDPLDEAEVYKRSDKLVLLVDVGG------HERYLRTALRQPDYVMLVVAANSGVQKMTKEHL-GIAVAIGIPVFVVVTRIDITPSEVFQKTVEEVVRILKM.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 275
52 -10.500[R] KOG1489 Predicted GTP-binding protein (ODN superfamily)  ali follow..  17  335..............................................................ELKSIAD--------LGLIGLPNAGKSTILNKISNAKIGHWQFTTLSPTIGTVSLGFG--------------------------------------------------QDVFTVADIPGIIQGASLDKGMLRHIERSNGWVFVLDLSNKNPLNDLQLLIGTLEKVKTKNILIVCNKVDIDAEKSE--SFAKYLQVEKFSK------------SQEWDCVPISALRE..................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 497
53 -10.500[J] COG0050 GTPases - translation elongation factors  ali follow..  14  1...............................................................MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITT--------------------------VLAKTYGGSARAFDQIDNAPE--------EKARGITINTSHVEYDTPARHYAHVDCPG------HADYVKNMITQMDGAILVVAATDGPMPQTREHI-LLGRQVGVPYIIVFMNKCDMVDDEE---------LLELVEMEVRELLSAYDFPGDDLPVVRGSALKALEGEAE............................................................................................................................................................................................................................................................................................................................................................................................................................................................... 184
54 -10.500[R] KOG1533 Predicted GTPase  ali follow..  10  1............................................MQMNLNEKKQLLRVRVYATSEKGENLGSTHWYGVLVIGAPGAGKSTFCAGLTKRPFLTINLDPANDTM--------------YAPDVNITEMITVNDVMDRLGLGPNGALKYCIETLGANCNIEANHKKYLIIDCPGQLELYKSEGELWKVIRFLECALHLADS--LYCSDPSKFISVALSTLAT--QVNCLSKADLFSED................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 210
55 -10.400[U] KOG0077 Vesicle coat complex COPII, GTPase subunit SAR1  ali follow..  12  16......................................................................LWQKEAKILFLGLDNAGKTTLLHMLKDERL--VQHQPTQHTSEELSIGKIK----------------------------------------------------FKAFDLGG---HQIARRVWKDYYAKVDAVVYLVDAYDKERFAEKRELDALLSDEALATFLILGNKIDIPYAASEDELRYHLG-----LTNFTTGKGKVTLGDSGVRPLEVFMCSIVRKM................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 179
56 -10.400[R] KOG0393 Ras-related small GTPase, Rho type  ali follow..  14  2.........................................................................QAIKCVVVGDGAVGKTCLLLSYTTNA-FPGEYILTV---------DTYSTNVMVDGRPIN----------------------------------------LSLWDTAGQDDYDQFRHLSF---PQTDVFLFALNNPASFENVRAKWYPEVSHHCPNTPIILVGTKADL-REDRDTIERLRESRLQPVSHTQGYVMAKALTQIGLKQVFDEAIRTGLTPPQTPQTRAKKS....................................................................................................................................................................................................................................................................................................................................................................................................................................................... 190
57 -10.200[R] KOG0075 GTP-binding ADP-ribosylation factor-like protein  ali follow..  13  12..................................................................FKSIFWKEEMELTLVGLQFSGKTTFVNVIASGQFA-EDMIPTVGFMRKITRGNVT----------------------------------------------------IKVWDIGG---QPRFRSMWERYCRGVNAIVYMVDAADLDKLEARNELHSLLDKPQLAGVLVLGNKRDLPGALDETG--------------LIERMNLSSIQDREICCYSISCKEK..................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 167
58 -10.200[R] KOG2485 Conserved ATP/GTP binding protein  ali follow..  11  60LSSANEDLQSQMSAKRRI-NKKDLANPNVLNVIRFFKWTRHFESSKQDCIAINAHSRSSVMKLLDLVELKLKEPTLLVMVVGVPNVGKSALINSIHQLKRATVGPLPVTQDIAGFKIAHRP---------------------------------------------------SIYVLDSPGVDIETGLKLALSGSVKDAQYFLAILNIRGTPLHWKYLVEGINEGPHADCIDKPSYNLKDLRHQRTKQPDSSALHYVGDMISEVQRSLYITLSEFDGDTEDENDLECLIEQQFEVLQKALKIPHKASEARLMVSKKF------LTLFRTGRLGPFILDDVPETETDHPNSKRVVV.................................................................................................................................................................................................................................................................................................................................................................................................. 390
59 -10.200[K] KOG1534 Putative transcription factor FET5  ali follow..  12  4...........................................................................VAAFVCGVASSGKSTFCGALVGRSCHLVNLDPAAENF--------------WEPTVDIRDLISIDDVMEELDYGPNGGLIYCFEFLMENLDIGDYDEDYLIFDMPGQIELYTHVPILPALIRHLQCAVYLLES--QFLVDRTKFFAGVLSAMSA--HINLLSKMDLLKDNNNI............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 184
60 -10.000[R] KOG2484 GTPase  ali follow..  13  147VIENADVVLEVVDARDPLGTRCNEVERAVRGAPGNKRLVLVLNKADLVPRENLNNWIKYFRRSGPVTRNKGIKTSIRVGVVGIPNVGKSSIINSLTRGRSCMVGSTPVTKSMQEVE-----------------------------------------------------LDSKIKLIDCPGIGDVKDPFTIAESVLKRASKEYFCTMYDITNYDTFEEFFAKKAARMGK................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 388
61 -9.870[T] KOG1486 GTP-binding protein DRG2 (ODN superfamily)  ali follow..  14  2.......................GIIERIKEIEAEMARTQKNKATEYHLGQLKA-KIAKLRTQLLEPPKGASGGG-RVALIGFPSVGKSTLLTMLTGTEAASYEFTTLTCIPGVIHYNDTK----------------------------------------------------IQLLDLPGISEGKGRGRQVIAVAKSSDLVLMVLDASKSEGHRQTKELEAVGLRLNKTPPQIYFKKKKT.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 184
62 -9.800[R] KOG1424 Predicted GTP-binding protein MMR1  ali follow..  15  365.......................................................SKQELLELFKELHRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATP-TKHFQTL-----------------------------------------------------YVEPGLCLCDCPGL---------VMPSFVSTKAEM-TCSGILPIDQMRDHVVSLVCQNIPRHVLEATYGINIITPREDED............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 499
63 -9.690[J] COG4108 Peptide chain release factor RF-3  ali follow..  13  17............................................................................TFAIISHPDAGKTTITEKVL-----------FGRAIQVA-------------------TVKGRGSNQHAKSDWMEMEKERGISVTTSVMQFPYGDCLVNLLDTPG---HEDFSEDTYRTLTAVDSCLMVIDAAKGVEDRTRKLMEVTRLRDTPIVTFM--NKLDREIRDPMELMDEVENELK................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 165
64 -9.630[R] KOG0074 GTP-binding ADP-ribosylation factor-like protein ARL3  ali follow..  15  13......................................................................APDQEVRILLLGLDNAGKTTLLKQLASEDI--SHITPTQGFIKSVQSQGFK----------------------------------------------------LNVWDIGG---QRKIRPYWKNYFENTDILIYVIDSADRKRFEEGQELAELLEEEKLSCVLIFANKQDLLTAAPASE--------------IAEGLNLHTIRDRVWQIQSCSALTG..................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 163
65 -9.620[R] KOG0394 Ras-related GTPase  ali follow..  17  9...........................................................................LKVIILGDSGVGKTSLMNQYVNKKF-----------------------------SNQYKATIGADFLTKEVQFEDRLFT-------------------LQIWDTAG---QERFQSLGVAFYRGADCCVLVYDVNSMKSENLNNWREEFLIQASPSDFVLIGNKVDVDDGNSRVVSEKKAKAWCASKGNIPYFETSAKVGTNVEEAFQCIAKDALKSGEEEE............................................................................................................................................................................................................................................................................................................................................................................................................................................................. 184
66 -9.610[J] COG3276 Selenocysteine-specific translation elongation factor  ali follow..  13  1...........................................................................MIIVTSGHVDHGKTALLKALTGTS-----------------------------------------------TAHLPEEKKRGMTIDLGYAYLPLENKVLGFIDVPG------HEKFLSNMLAGLHYAMLIVAADEGVAVQTKEHL-AILRQLQFHEIIVVITKADRTNSA--------------QIESLIQTIKQDYSFLRNANYFVTSAETG--------------------------QGISELRHYLANLAELADTQKPFRYAIDRVFSV.......................................................................................................................................................................................................................................................................................................................................................................................................... 181
67 -9.590[D] COG0455 ATPases involved in chromosome partitioning  ali follow..  13  24...........................................................IYDQASGLRRLTQPSVTKVISVGKGGVGKSNVLGMAIGKKVMVLDAIRPKRNLGHVLAGECELKDAIVEGPHGIRIIPATSGTQSMTELSHAQHVGLIRAFGTLEDEMDIL-----LIDTAGISDM------VVSFSRAAQDVVVVVCDEPTSITDAYALIKLLSKEHQVQRFKIVANMVR--YREGRELFAKLTLVTERFLNVSLELVACIPLDD--------NVRQAVKRQK-----------VDAYPRSPAALAISSLANKALTWPIPRTPSGHLEFFVERLLNRSET....................................................................................................................................................................................................................................................................................................................................................................................................... 306
68 -9.580[R] COG3911 Predicted ATPase  ali follow..  10  8............................................................................VFVLTGGPGSGKTTLIAALAGFATSV-----------------VAGRGIVRDQSSIGGTALPWSDRTLFAELMLSWEMRSYQNAVE--------QKGPVFFDR-------------------PETLGYL----RLSGLPVADHVSTAAKRFRYNPRVFIAP--DEERKQTPDEAKCTYHALAEIYTELGYELVPLPLAPVETRLRFVLADAGLN................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 183
69 -9.520[D] COG3640 CO dehydrogenase maturation factor  ali follow..  14  5.........................................................................GMPKLIISGRGGSGKSTLVTLIAKKRVLVVDSDESNIGLSGILGIEPAEKTLMDYLGGKPRVMKKLRSMIRDGETEPELFREKFDLESLSQPMGAVTRDQWVLVDTEGVEH------FGRGIVEGADAVVMVVDPSSDAVLLAEKAAKLTHEAD---RFGVILNKID--EETEPILTELLTSEGNEIKGVLPYSPAITKMNLKGESLGAYAVKNEVDEIIRE.............................................................................................................................................................................................................................................................................................................................................................................................................................................................. 259
70 -9.500[I] KOG0064 Peroxisomal long-chain acyl-CoA transporter, ABC superfamily  ali follow..  427AADAIERLMSSYKEIVSLAGYTFRVAGMMDVFEETALGVYCKTSVMESNQSNGIIEFRNGKPIVPKLTLCIEPGV-HLLITGPNGCGKSSLFRILSG--YIPQRPYMSIGSL-QIIYPDMKRKHITENELRSILKMVSLEHIAQRDSFDVVRDWKDILEKQRMAIARLFYHRRYALLDTSAVSI--DVESSIYEIAKGMGITLLTITHRPTLWKYHTHILE........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 706
71 -9.480[U] KOG0076 GTP-binding ADP-ribosylation factor-like protein yARL3  ali follow..  13  14.......................................................................KKEQYSILILGLDNAGKTTFLETLKKEYSLAEKIQPTVGQVATIPVDSKQI---------------------------------------------------LKFWDVGG---QESLRSMWSEYYSLCHGIIFIVDSSDRERLDESTTLQSVVMDEEIEGILMLANKQDR.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 137
72 -9.460[R] KOG0091 GTPase Rab39, small G protein superfamily  ali follow..  12  10...........................................................................FRLILIGDSTVGKSSLLKFFTDGKFAELSD-PTVGV--------------------------------DFFARLIEMKDGTQIK--------------LQLWDTAG---QERFRSITKSYYRNSVGVLLVYDISNHASFEHPLWMMEAQRHIEPHRPALVGCKLDLINAGGHREVTTEEAQKFAKQHGLHFVETSARSGANVEEAFRMVTQEVYARIRSGE............................................................................................................................................................................................................................................................................................................................................................................................................................................................. 183
73 -9.450[E] COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family  ali follow..  11  37.........................................................QALSTQLLDAIMPYCGNTLRLGVTGTPGAGKSTFLEAFGGLKVAVIAVDPSSPVTGGSILGDKTRMNDLARAEAAFIRPVPSSGHLGGASQRAREL-------------CEAAGYDVVIVETVGVGQSE------TEVARMVDCFISLQGGGDDLQGIKKGLME-----------LIVINKDDGDNHTNVAIARHMYESALHILRRKYDE---------QPRVLTCSALEK--------------------------RGIDEIWHAIIDFKTALTASGRLQQ--VRQQQSVEWLRKQTEEEVLNHLFANEDFDRYYRQTLLAVKNNTLSPRTGLRQLSEFIQT..................................................................................................................................................................................................................................................................................................................................................... 327
74 -9.440[R] KOG0079 GTP-binding protein H-ray, small G protein superfamily  ali follow..  14  11...........................................................................FKLLIIGDSGVGKSSLLLRFA-DNTFSENYITTIGVDFKIR-------TMDINGQRVK----------------------------------------LQIWDTAG---QERFRTITSTYYRGTHGVVVVYDVTNGESFGNKRWLQEIENNCDSVQKVLVGNKCEENERRVVLESDARNYAQSMNISFFETSAKE---DKNVEPMFTCITSLVLTAKLANP............................................................................................................................................................................................................................................................................................................................................................................................................................................................. 178
75 -9.440[J] KOG0465 Mitochondrial elongation factor  ali follow..  11  72............................................................................NIGISAHIDSGKTTFTERVL--------YTKRIKAIHEVRGRDNVGAKMDSMDLEREKGITIQSAATYCSWDKEGKN------------------YHFNLIDTPG---HIDFTIEVERALRVLDGAVLVVCAVSGVQSQTVTVDRQMRRYNVPRVTFI--NKMDRMGSDPFRAIEQLNSKL-------------------KIPAAAVQIPIGSESSLSGVVDLINRVAIYNKGDNGEIIEKGPVPENLKPLMEEKRQLL--------IETLADVDDEMAEMFLEEKEPTTQQIKDAIRR.............................................................................................................................................................................................................................................................................................................................................................................. 313

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Bossy-Wetzel E, Barsoum MJ, Godzik A., Schwarzenbacher R, Lipton SA. Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr Opin Cell Biol. 2003 Dec;15(6):706-16. Review.