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Query: [J] KOG0468 U5 snRNP-specific protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDSDLYDEFGNYIGPDLDSDEEDEQSIYGQPDVQDDPEDAMDEDEVEPQEDEDKEVTAVVLHEDKRYYPSAVEVYGPDVETIVQEEDAQPLDKPLIEPVKKLKFQIKEQDMQETTYDMEFMADLMDTPPLIRNVALVGHLHHGKTTFVDCLIRQTHPQFETMEERQLRYTDTLFTEQERGCSIKATPVTLVLQDVKQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQERQAITVCINKIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTYGAPDDNLLVSPILGNVCFASSLYGFCFTLKSFAKLYADTYEGVAYLDFAKRLWGDMYFNSKTRKFSKKQPHNSAQRSFVEFILEPMYKLIAQVVGDVDTTLSDTLAELNVRVSKEEMKSNIRPLLRLVCNRFMGDCSGFVDMCVEHIKSPLENAKRKVDHIYTGPKEGDIYRDMISCNQYGTLMVHSSKMYPNDDCTFFQVLARIVSGTLHAGQEVRVLGENYTLQDEEDSRILQVGRLWVFESRYKVELNRVPAGNWVLIEGIDQCIVKTSTIVDINVPEDLYIFRPLKFNTQSIIKIAVEPVNPSELPKMLDGLRKVNKSYPLLSTRVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVAFCETVVETSSLKCFAETPNKKNKITMISEPLEKGLAEDIENGTVCINWNKKRIGEFFQVNYDWDLLAARSIWAFGPDSTGPNILVDDTLPSEVDKNLLTAVKDSIVQGFQWGTREGPLCEEPIRNVKFKILDGVIANEALHRGGGQIIPTARRVAYSAFLMATPRLMEPYLFVEVQAPADCVSAVYTVLARRRGHVTQDAPVSGSPIYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIIIRPLEPQQASHLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELARQDVLINYPLLast
1 -290.000[J] KOG0468 U5 snRNP-specific protein  ali  100  1MDSDLYDEFGNYIGPDLDSDEEDEQSIYGQPDVQDDPEDAMDEDEVEPQEDEDKEVTAVVLHEDKRYYPSAVEVYGPDVETIVQEEDAQPLDKPLIEPVKKLKFQIKEQDMQETTYDMEFMADLMDTPPLIRNVALVGHLHHGKTTFVDCLIRQTHPQFETMEERQLRYTDTLFTEQERGCSIKATPVTLVLQDVKQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQERQAITVCINKIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTYGAPDDNLLVSPILGNVCFASSLYGFCFTLKSFAKLYADTYEGVAYLDFAKRLWGDMYFNSKTRKFSKKQPHNSAQRSFVEFILEPMYKLIAQVVGDVDTTLSDTLAELNVRVSKEEMKSNIRPLLRLVCNRFMGDCSGFVDMCVEHIKSPLENAKRKVDHIYTGPKEGDIYRDMISCNQYGTLMVHSSKMYPNDDCTFFQVLARIVSGTLHAGQEVRVLGENYTLQDEEDSRILQVGRLWVFESRYKVELNRVPAGNWVLIEGIDQCIVKTSTIVDINVPEDLYIFRPLKFNTQSIIKIAVEPVNPSELPKMLDGLRKVNKSYPLLSTRVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVAFCETVVETSSLKCFAETPNKKNKITMISEPLEKGLAEDIENGTVCINWNKKRIGEFFQVNYDWDLLAARSIWAFGPDSTGPNILVDDTLPSEVDKNLLTAVKDSIVQGFQWGTREGPLCEEPIRNVKFKILDGVIANEALHRGGGQIIPTARRVAYSAFLMATPRLMEPYLFVEVQAPADCVSAVYTVLARRRGHVTQDAPVSGSPIYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIIIRPLEPQQASHLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELARQDVLINYPL 975
2 -227.000[J] KOG0469 Elongation factor 2  ali follow..  36  1................................................................................................................MVNFTVDEIRALMDRKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAG-SKAGETRFTDTRKDEQERCITIKSTAISLFFEKEKYNGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLFMNKMDRALLELQLGAEELFQTFQRIVENINVIIATYDGPMGPIMVDPSIGNVGFGSGLHGWAFTLKQFAEMYAGKFG-VQVDKLMKNLWGDRFFDLKTKKWSST-QTDESKRGFCQFVLDPIFMVFDAVMNIKKDKTAALVEKLGIKLANDEKDLEGKPLMKVFMRKWLPAGDTMLQMIAFHLPSPVTAQKYRMEMLYEGPHDDEAAVAIKTCDPNGPLMMYISKMVPTSDKGRFYAFGRVFSGKVATGMKARIQGPNYVPGKKEDLYEKTIQRTILMMGRFIEPIEDIPSGNIAGLVGVDQYLVKGGTITT---YKDAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIFEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVQSESNQICLSKSPNKHNRLHCTAQPMPDGLADDIEGGTVNARDEFKARAKILAEKYEYDVTEARKIWCFGPDGTGPNLLMDVTKGV----QYLNEIKDSVVAGFQWATREGVLSDENMRGVRFNVHDVTLHADAIHRGGGQIIPTARRVFYASVLTAEPRLLEPVYLVEIQCPEAAVGGIYGVLNRRRGHVFEESQVTGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPLEAGTK------------PNQIVLDTRKRKGLKEGVPALDNYLDKM............... 852
3 -132.000[J] COG0480 Translation elongation factors (GTPases)  ali follow..  19  1.........................................................................................................................MARINPLEKVRNIGIAAHIDAGKTTTTERILFYSGIIHKIGEVHETAVTDWMDQERERGITITAAAISTSW-----KDYQINIIDTPGHVDFTIEVERSMRVLDGVIAVFCSVGGVQPQSETVWRQADRYKVPRIAFINKMDRTGANFYRVHEQMRDRLRANAIAIQLPIGSENDFKGIVDLVRKRAYMYNNDQ-------------------------------------GTDIEETDIPADLQDQVEEYYTKLVEAVAETDDDLMSKYFDGEPLTEEEIRSALRKGTIAGTIVPVLCGSAFKNKGV-QLMLDAVVDYLPAPTEVPPIQG-------TLPNGDAIERRADDNEPLAALAFKIM--ADPYGRLTFVRVYSGVLKKGSYVL---------NATKNKKERISRLVLMKADDRQDVEELRAGDLGAALGLKDTLTGDTI-----TDEGAPVILESLFIPEPVISVAVEPKTKNDMDKLSKALQSLSEEDPTFRVNVDETNQTVIAGMGELHLEILVDRMLREF-KVEANVGAPQVAYRETIRKPVTVEGKFIRQSGGKGQYGHVVINLEPGEP-------------------------------GTGFEFVSKIVGGVV--------------PKEYIGPAEQGMKESCESGILAGYPLIDVKATLVHGSYHDVDSSEMAFKI--AGSMALKEAVLKASPVLLEPMMKVEVEVPEDYIGNVIGDLISRRGQIESQSTEQGLA--KVASKVPLATMFGYATDIRSKTQGRGIFTMEFSHYEEVPRSVAETIIAKSKGN.................................................. 691
4 -119.000[J] KOG0465 Mitochondrial elongation factor  ali follow..  18  66..............................................................................................................................RCNKLRNIGISAHIDSGKTTFTERVLYYTKRIKAIHEVRGGAKMDSMDLEREKGITIQSAATYCSWD-KEGKNYHFNLIDTPGHIDFTIEVERALRVLDGAVLVVCAVSGVQSQTVTVDRQMRRYNVPRVTFINKMDRMGSDPFRAIEQLNSKLKIPAAAVQIPIGSESSLSGVVDLINRVAIYNKGDN-------------------------------------GEIIEKGPVPENLKPLMEEKRQLLIETLADVDDEMAEMFLEEKEPTTQQIKDAIRRSTIARSFTPVLMGSALANTGI-QPVLDAIVDYLPNPSEVLNTALDV------SNNEAKVNLVPAVQQPFVGLAFKL--EEGKYGQLTYVRVYQGRLRKGNYIT---------NVKTGKKVKVARLVRMHSSEMEDVDEVGSGEICATFGID------CASGDTFTDGSVQYSMSSMYVPDAVVSLSITPNS-KDASNFSKALNRFQKEDPTFRVKFDESKETIISGMGELHLEIYVERMRREY-NVDCVTGKPQVSYRESITIPADFDYTHKKQSGGAGQYGRVIGTLSPVDDI------------------------------TKGNIFETAIVGGRI--------------PDKYLAACGKGFEEVCEKGPLIGHRVLDVKMLINDGAIHAVDSNELSFKT--ATMSAFRDAFLRAQPVIMEPIMNVSVTSPNEFQGNVIGLLNKLQAVIQDTENGHDEF--TLKAECALSTMFGFATSLRASTQGKGEFSLEFSHYAPTAPHVQKELISEFQKKQAKK.............................................. 761
5 -87.600[T] COG1217 Predicted membrane GTPase involved in stress response  ali follow..  16  3................................................................................................................................ENLRNIAIIAHVDHGKTTLVDKLLKLSGTLDR-KEAESERVMDSNDQEKERGITILAKNTAIKW-----NGYNINIVDTPGHADFGGEVERVMSMVDSVLLVVDAQDGPMPQTRFVTQKAFKAGLRPIVVVNKIDRPGARPDWVIDQIFDNLGATDEQLDFPIVYASALNGIAGLDHEKMDD-----------------------------------------------------------------------------------------------------------------------MDALFQAIIDHVPAPVV--------------------------DTEGPFQMQISQLDYNSFLGVIGIGRITRGKVKSNTPVVAISDD------GSKRNGRILKIMGHHGLQRVEVAEAEAGDIVCVSGMEELFISDTL-----CDPQNVEALPPLTVDQPTVSMTFREGKFVTSRNIKERLEKELLHNVALRVEPGSPEKFKVSGRGELHLSVLIETMRREG--FELAVGRPEVVIIEKDGEKQEPYENVTIDIEEQHQGSVMEQMGLRKGDLSNMIPDGKGRV------------------------------------------RLEYTIPARGLIGFRNNFLTLTSGTGILTSTFSHYGPIKAGEVSNRQNGVLVSMATGTALTYSLETLQSRG-KLFLGPGDEI-------YEGQLAGINSRDNDLVIN----PTKGKKLDNMRASGKDEVIALVPPIRFTLEQALEFIADDELVEVTPK-------------------------SIRLRK--------------KMLNENDRKRYERSKV. 605
6 -86.300[J] COG4108 Peptide chain release factor RF-3  ali follow..  14  6.........................................................................................................................TPYFGEVSKRRTFAIISHPDAGKTTITEKVLLFGRAIQVAGTVKGHAKSDWMEMEKERGISVTTSVMQFPY-----GDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDAAKGVEDRTRKLMEVTRLRDTPIVTFMNKLDREIRDPMELMDEVENELKIACSPITWPIGCGKEFKGVYHIHRDETILYTSG----------------------------------------------QGHTIQEERIIKGLDNPELDQAVGADLAAQLREELELVLGASHEFDRELFLQGELTPVFFGTALGNFGV-DHMLDGLTQWAPSPMPRQAAE-------------RVVEASEEKFTGFVFKIQANM-DPKHRDRIAFVRIVSGTYKQGMKMN---------HVRLGKQVNISDAVTFMAGDRARAEEAFAGDIIGLHNHGTIQIGDTFTQGE------TLKFTGIPNFAPELFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVFRPLQNNDLIVGAVGVLQFDVVVSRLKSEY-NVEAIYEGVNVATAECDDVKKFEEFKRKNQSNLALDGGDNLAYIAPT.................................................................................................................................................................................................................................................................................... 509
7 -82.500[M] COG0481 Membrane GTPase LepA  ali follow..  19  2................................................................................................................................KNIRNFSIIAHIDHGKSTLSDRLIQTCGGLSDREMEA--QVLDSMDLERERGITIKAQSVTLNYKAKDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIEMNLEVVPILNKIDLPAADPERVAEEIEDIVGIDAMEAVRCSAKTGV------------------------------------------------------------------------------------------------------------------------------------GIEDVLEEIVHKIPAPEGDPNAPLQ--------------------------ALIIDSWFDNYLGVVSLVRIKNGTLRKGDKIKVMSTG------QSYNVDRLGIFTPKQVDTTILNCGEVGWVVCAIKDILGAPVGDTLTSHNNPASSV---LPGFKKVKPQVYAGLFPISSDDYEAFRDALGKLSLNDASLFYEPENSTGFRCGFLGLLHMEIIQERLEREY-DLDLITTAPTVVYEVEKTDGEVIYVDSPSKLPPLNNITE------------------------------------------------------------------------------------------------------------------------------------------IREPIAECNMLLPQTYLGNVITLCVEKRGVQTNMVYH-GNQVALTYEIPMGEVVLDFFDRLKSTSRGYASLDYGFKRFQAADMVRVDIMINGERVDALAAPYRGRELVEKMRE-RQQ--DIAIQAAIGNHIIVKQLRKNVLAK... 552
8 -80.100[J] KOG0462 Elongation factor-type GTP-binding protein  ali follow..  15  39...............................................................................................................................PDKIRNFGIVAHVDHGKSTLADRLLEMCGAVPPGQK----QMLDKLQVERERGITVKAQTAALRH-----RGYLLNLIDTPGHVDFSAEVSRSLAVCDGILLLVAANQGVQAQTIANFWLAFEKNIQIIPVINKIDLPGADIKSVETQLKNLFEFNPEECLHISAKSGL------------------------------------------------------------------------------------------------------------------------------------NVDKVLEAIIDRVPAP-------------------------TAIIDAPFRSMIFD-SYFDHFRGAIAHIMVKEGSVKKGDKIQSYQNE---------KVYDVSEVGVMRPEKCTELRAGQVGYLVCMRTVNEAVVGE-TLFAETTSRDSVKTFAEIKGVKPTVYAGLFPVETSDYESLKQAVERLCLNDPSVTVIPDSSKGWRIGFLGVLHMEVFGARLSQEY-DASVILCQPSVEYRAKIKDNETIRKKRYDGMEEIRILDPSKFPDESDVDSFLEPMVKVR-----------------------------------------------MIVPNEMMGTVNGLCSECRGERGEITSIDSTRLVILWRLPLAEVAVDFERLKKLTSGYASFDYEPDGWQDTRLVKLTILINSKEVSEFSQIIPAMARDRAKILVQRLKREIP--RQQFEVTIKACIGSSTKAIVIQPMKRDFSQLLKGN-------------------GGGMERLNKKLSHQKKGKERMKMVGNVQIPKEAFLNVLKR......... 645
9 -29.300[J] KOG0460 Mitochondrial translation elongation factor Tu  ali follow..  18  55....................................................................................................................................NIGTIGHVDHGKTTLTAAITKCLSDLGQ-ASFMDYSQIDKAPEEKARGITISSAHVEY-----ETANRHYAHVDCPGHADYIKNMITGAATMDGAIIVVSATDGQMPQTREHLLLARQVGVKQVVYINKVDMVEPD----------MIELVEMEMRELLSEYGFDGDNTPIVSGSALCALEGREPEIGLN----------------------------------------------------------------------------------------------------------SITKLMEAVDSYITLPER-------------------------KTDVPFLMAIEDVFSISGR-GTVVTGRVERGTLKKGAEIEIVGYG-------SHLKTTVTGIEM----FKKQLDAAVAGDNCGLRSIKREQLKRG-------------------------MIVAQPGTVAPHQKFKASFYILTKEEGGRRTGFVDKYRPQLSRTSDVTVELTHPDPNDDNVEMICTLIHPIV........................................................................................................................................................................................................................................................................................................................ 413
10 -27.100[J] COG0050 GTPases - translation elongation factors  ali follow..  18  14....................................................................................................................................NVGTIGHVDHGKTTLTAAITTVLAKTYG-GSARAFDQIDNAPEEKARGITINTSHVEY-----DTPARHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIVFMNKCDMV---------DDEELLELVEMEVRELLSAYDFPGDDLPVVRGSALKALEG------------------------------------------------------------------------------------------------------------EAEWEAKIIELAGYLDSYIPEPER-------------------------AIDKPFLLPIEDVFSISGR-GTVVTGRVERGIVKVGEEVEIVGIK-------DTVKSTCTGVEM----FRKLLDEGRAGENVGLRGIKREDIERG-------------------------QVLAKPGSIKPHTTFESEVYILSKDEGGRHTPFFKGYRPQFFRTTDVTGTIELPEGVEMVMPMIVTLIHPIA........................................................................................................................................................................................................................................................................................................................ 368
11 -26.400[J] KOG0052 Translation elongation factor EF-1 alpha/Tu  ali follow..  15  1............................................................................................................................MGKEKVHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKVLDKLKAERERGITIDIALWKF-----ETAKYYITIIDAPGHRDFIKNMITGTSQADCAVLVVACGTGE--QTREHALLAQTLGVKQLIVCNKMDSTEPPFS------EARFTEITNEVSGFIKKIGYNPKAVPFVPISG-------------------------------------FNGDNMLEVSSNMPWFKGWAVERKEGNAS-------------------------------------------------------GKTLLEALDSIIPPQRPTDR----------------------------LRLPLQDVYKIGGIGTVPVGRVETGIIKPGMVVTFAPQN---------VTTEVKSVEM----HHESLPEAVPGDNVGFN-VKNVSVKDIRRGSVCSDSKQDPAKEARTFHAQVIIMNHPGQISNGYTPV------LDCHTAHIACKFNELKEKVDRRTGKKVEDFPKFLKSGDAGIVELIPTKPLC........................................................................................................................................................................................................................................................................................................................ 411
12 -25.700[J] KOG0466 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  14  43....................................................................................................................................NIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITILDDPSCPRPECYRSCGSSMPDEFPGNFRLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCQPQTSEHLAAIEIMKLKHLILQNKIDLV-----------------------------------------------------------------------------------------------------------------------------KERQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNI---EVVCEYIVKKIPVPPR-------------------------DFTSEPRLIVIRSFDVNDLKGGVAGGSILKGVLKVGQETEVRPGIVSKDSEGKLMCKSIFSKIVSLFAEHNDLQYAAPGGLIGVTKIDPTLCRADRMVGQILGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLVNIGSLSTGGRVSAVKADL---------------GKIVLTNPVCT....................................................................................................................................................................................................................................................................................................................... 435
13 -25.100[P] COG2895 GTPases - Sulfate adenylate transferase subunit 1  ali follow..  15  21............................................................................................................................AQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNLVDGLQAEREQGITIDVAYRYF-----STEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVINKMDLVDYS-EETFTRIREDYLTFAGQLP--------GNLDIRFVPLSA-------------------------------------LEGDNVASQSESM----------------------------------------------------------------------SGPTLLEVL---------------------------ETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSG---------VESNVARIVTFDG----DREEAFAGEAITLVLTDEIDISRGDLLLAADE----ALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKRVDGIRYQVDINNLTQREVENLPLNGI-------------GLVDLTFDEPLV........................................................................................................................................................................................................................................................................................................................ 405
14 -24.900[J] COG5256 Translation elongation factor EF-1alpha (GTPase)  ali follow..  22  1.........................................................................................................................MKIMASQKPHLNLITIGHVDHGKSTLVGRLLYEHGEIPAHIIEEYRKVMDRFKEERERGVTIDLAHRKF-----ETDKYYFTLIDAPGHRDFVKNMITGTSQADAAILVISAREGVMEQTREHAFLARTLGVPQMVVINKMDATSPPYSEK-NEVKADAEKLLRSIG............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 180
15 -24.600[J] KOG0458 Elongation factor 1 alpha  ali follow..  10  39..PTLKAQLQDYQGWDNLSLKLALFDNNFDLESTLAELKKTLKKKKTPKKPIAAANGSANVTQKLANISISQQRPNDRLPDWLDEEESEGERNGEEANDEKTVQRYYKTTVPTKPKKPHDISAFVKSALPHLSFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRIMDQTNEERERGVTVSICTSHF-----STHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNA--QTKEHMLLASSLGIHNLIIMNKMDNVDWS--------QQRFEEIKSKLLPYLVDIGFFEDNINWVPISG-------------------------------------FSGEGVYKIEYTDEVRQ-------------------------------------------------------------------GPNLMSTLENAAFKISKENEGI--------------------NKDDPFLFSVLEIIKKTSNDLALVSGKLESGSIQPGESLTIYPSE---------QSCIVDKIQVGSQQGQEETDVAIKGDFVTLK-LRKAYPEDIQNGDLAASVDYSSIHSAQCFVLELTPFILFIGVKEQPARIKRLISFIDKGN-FVEIELIEVGRVVLRKDGRTIAAGKISEITQ...................................................................................................................................................................................................................................................................................................................................... 611
16 -24.200[R] COG5258 GTPase  ali follow..  15  2................FPPESEDGNVEYKLTLGPQDVDRMAGQLKRRLAEGGGEAVYLIGVSNDGRPLGLPDEELVKALETLREMARRVGASLYILRVSEGIRGKVAEVLLRAVSREEPPPT----------TVVALGNVDAGKSTLVGVL---TTGRLDDGKGLARSYASRYKHEVLTGRTSAVSLRLLGFSGDKRSDKLVLLVDVGGHERYLRTALRGLSQPDYVMLVVAANSGVQKMTKEHLGIAVAIGIPVFVVVTRIDITPSE----------VFQKTVEEVVRILKMPGVSKIPYIIKDTNDVVLAAKAMPA----------------------------------------------------------------------------------------------GRVAPVFYVSSVTGHGL--DLLLRFLSLLPRRRRW------------------------DYGGEFLMYISDIYLVKG-VGVVIGGLVEKGILHVGDRVWL-----GPYSDGKWMQTVVKSIHF----NRTPVESAKAGSFITVALDKVEKVEKGMVLSARPLKAVREVTADVLVLRHPTVIRIKEIDKGELMVGDSGVVKIELSRPWH-----DSGVFVFRILGRI................................................................................................................................................................................................................................................................................................................................................. 508
17 -23.300[J] COG5257 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  17  8....................................................................................................................................NIGLVGHVDHGKTTLTKALS--------------GVWTDTHSEETKRGISIRTAEICERCGTETELLRKVSFVDAPGHETLMATMLSGAALMDGAILVIAANEPCQPQTKEHLMALDVIGVKDIVVQNKIDIV-----------------------------------------------------------------------------------------------------------------------------SKERALESYREIKEFVKGTCAEDAPIIPVSAQQGANI---DILIETIEERIKTPKR-------------------------DVDKPARMYVARSFDIEHLAGGVIGGSLVQGRLRVGDEIEIRPGIQVKKDGKQTWMSLHSTITGLVAGG-EEMEEVGPGGLVGVTLLDPALTKADSLSGSV-----------------AGEPGTLPPVRHSFTMETHLLERVVGTKEETKVEPIKTGEPLMINVGTTTTVGVVKSARADD--ADVVLKLPACA....................................................................................................................................................................................................................................................................................................................... 383
18 -22.700[J] KOG0459 Polypeptide release factor 3  ali follow..  13  1................MDLEAEIRALQLESADENNGVVIPEVHNSHEVENLDKAPEDLKDEVQESIPVPDEQEASEDHDEVMLHPVHNPAKAKEKAAQEKAAKEEAEDVA--------------EANKKRHLNVVFIGHVDAGKSTIGGQILFLSGQVDDRQIQKYEKIMDTNEEERLKGKTVEVGRAHF-----ETESTRFTILDAPGHKSYVPNMISGASQADIGVLVISARKGE--QTREHVQLAKTLGVSKLIVVNKMDDPTVNWSKE-DEIEQKMVPFLKASGY------NTKKDVVFLPISG-------------------------------------LMGKNMDQRMGQEICPWWSG-----------------------------------------------------------------PSFFEVL-DSIEIPPR-------------------------DPNGPFRMPIIDKF---KDMGTVVMGKVESGSIREGDSLVVMPNK---------EQVKVVAIYC----DEDKVKRAGPGENLRITGIEDEDILSGFVLSSIVNPVP---------AVTEFVAQLQILELLDNAIFTAGYKILHIHAVVEECEIIELKSQIDLKTRKPMKKKVLFVKNGAAVVCRIQVTNSIC........................................................................................................................................................................................................................................................................................................................ 495
19 -20.300[J] KOG1145 Mitochondrial translation initiation factor 2 (IF-2; GTPase)  ali follow..  15  183.....................................................................................................................................VTIMGHVDHGKTTLLDKF----------------RKTQVAAVET--GITQHIGAFLVSLPSGE----KITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPE--------KVKKELLAYDVVCEDYGGDVQAVPVSALTG------------------------------------------------------------------------------------DNLMALAEATVALAEMLELKADPNGPVEGT----------VIESFT-------------------------------------------------DKGRGLVTTAIIQRGTLRKGSVLVA---------------KCWAKVRLMFDENGKTIDEAYPSMPVGITGWRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEE--KRKEHKEAHQKAREKYGHLLWKKRSILRFLERKEQIPLKPKEKREDSNVLSVIIKGDVDGSVEAILNIIDT---------------------------------------------------------------ASHECELELVHFGVGDISANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY----------RLVEDLQEELSS--------RLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFKLSLTSLKHHKDDISIVKTG............................................................................... 689
20 -18.400[E] COG4917 Ethanolamine utilization protein  ali follow..  17  1..................................................................................................................................MKRIAFVGSVGAGKTTLFNALQGNY-----------------TLARKTQAVEFNDK----------------GDIDTPGHPRWYHALITTLQDVDMLIYVHGANDPESRLPAGLLDIGV--SKRQIAVISKTDMPDADVAATRKLLLE......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 117
21 -18.200[J] COG3276 Selenocysteine-specific translation elongation factor  ali follow..  24  3.....................................................................................................................................IVTSGHVDHGKTALLKAL---TGT------------TAHLPEEKKRGMTIDLGYAYLPLENKV-----LGFIDVPGHEKFLSNMLAGLGGVHYAMLIVAADEGVAVQTKEHLAILRQLQFHEIVVITKADRTNSAQIESLIQTIKQDYSFLRNANYFVTSAETGQGISEL................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 154
22 -17.700[R] KOG2486 Predicted GTPase  ali follow..  16  132...............................................................................................................................ADGLPEFALVGRSNVGKSSLLNSLVRRKRLALTSKKPGKTQCINHFRINDK-----------------------WYLVDLPGY-KFTKDYFLNRSTLVSVFLLVDASIPVKPIDLEYASWLGQNQVPMTLIFTKCDKR...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 259
23 -17.000[U] KOG0090 Signal recognition particle receptor, beta subunit (small G protein superfamily)  ali follow..  16  53................................................................................................................................TKSNTVLLSGLSGSGKTVLFYQLRDGSSHQGAVTSMEP---------------NEGTFVLHNENNTKKGKVKPVHLIDVPGHSRLISKLEEYLPRAAAVVFVVDALE-IRAASEYLYDSVIKNKTPVLLCCNKTDKVTA---HTKEFIRKQMEKEIDKLR............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 202
24 -16.100[J] COG0532 Translation initiation factor 2 (IF-2; GTPase)  ali follow..  15  448.....................................................................................................................................VTIMGHVDHGKTTLLDRF----------------RESRVTEGEA--GITQHIGAYQIKANGKK-----ITFLDTPGHEAFTSMRARGASVTDITILVVAADDGVMPQTIEAINHSKAAGVPIIVAINKIDKPGANPQRVTQELTEH-------------------------------------------------------------GVFPVAWDP----------------------------------------------------------------ENGSEFVEISAKFNQNLDELLDTVL------------------------VAEVQELKADPTVRAIGTVVEA-RLDQGKGAIATLLVQQGTLHVQDPI-VVGNTY-------------GRVRTMTNDLGRRIKEAGPSTPIELTGLSDVPQAGDHFAVFEDEKAARAAGEERAKRA---LIKRQNTRRVNLDNLFDTLKEGQTKSVNIIIKADVQGS----------AEALAASLQK----------------------------------------------------------------------------------------IEVEGVKVDIVHSAVGAISESDISLAAASNAIIIGFNVRPTGLAREQAAQEEVDIRLHSIIY----------KVIEEVETAMRG--------MLDPEFKEEIIGEAI-VRETFNV--SKVGTIAGFMVIRGKVARDASVRVAIASLKHFKDDVKEVGNA--EGGLMVEDFNDVEIDDTFEVYKMVEIER................................................. 943
25 -15.300[R] COG3596 Predicted GTPase  ali follow..  14  40....................................................................................................................................VIGIMGKTGAGKSSLCNALF-----------------------AGEVSPVSDVAACTPLRFRLQIGEHFMTIVDLPGDTEYAALYREQLPRLDLILWLIKADDRALATDEHFYRQVIGEAYKMLFVISQSDKA...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 160
26 -14.900[R] COG2229 Predicted GTPase  ali follow..  19  5....................................................................................................................................KIIFTGPVGVGKTTAIAAISDEALVQTDASASDMT-----LDRKRNTTVAMDYGAISL------DEDTKVHLYGTPGQERFNFMWEILSQGSMGLVLLLDNARTNPLKDLEFFLHSFRGKAPVVVGITKMD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 127
27 -14.400[R] COG0218 Predicted GTPase  ali follow..  10  22...............................................................................................................................QDELPEIALAGRSNVGKSSFINTMLNRKNLARTSGKPGKTQLLNFFNIDDK-----------------------MRFVDVPGY-CMIEEYLTTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESAIKKKLNFDPSDDFILFSSVSKAGMDEA................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 187
28 -14.000[R] KOG0395 Ras-related GTPase  ali follow..  18  11..........................................................................................................................TLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGR----------EDQYTPTIEDFHRKVYNI------------RGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEELPMVICGNKNDHGELCRQVPTTEAEL......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 158
29 -13.900[TU] KOG1954 Endocytosis/signaling protein EHD1  ali follow..  13  1............MYNFFRTVPRANRNEITFYPDYEEEGQKKKKTRSMFSWLGGDSSKKKNKEVLETVSEGLRKIYKQKLLPLEEFHKFHDFHSPALDD-----------------------PDFDAKP-----ILLVGQYSTGKTTFIRYLLESDFPGIRIGEPTTDRFIAVMHGDEEGSIPGNALVVDAKKQFRALSGF-VTIVDTPGILDFTGVLEWFAERVDRIILLFDAHKDISDEFKRCIEALAGNEDKIRIVLNKSDMV------DHQQLMRVYGALMWSLGKVFKT.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 280
30 -13.800[R] COG1084 Predicted GTPase  ali follow..  15  152........................................................................................................................LRNMPTVDLDAFTVVIAGFPNVGKSTLLRTLTGAEPEVADY------------------FTTKGIQIGHLERKWKR-----IQVIDTPGLLDRPVEMVALENIADVIMFIFDASETCESQYSLYLGIRSVFDIPVVTVFNKMD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 285
31 -13.700[O] KOG0448 Mitofusin 1 GTPase, involved in mitochondrila biogenesis  ali follow..  10  1............................................................MAEPVSPLKHFVLAKKGITAIFDQLLEFVTEGSHFVEATYKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRVAFFGRTSSGKSSVINAMLWDTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK--LVLVDSPG--ELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEWLSKPNIFINRWDASASEPEYMEDVRRQHMERCLHFLVEELKVANALEAQNRIFFVSAKEVLSARKQKAQGMPES-ALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVNLAAEDKRHYSVEEREDQIDRLDIRNQMNLLTLDVKKKIKEVTEEVANKVSCAMTDEICRLSV.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 422
32 -12.500[R] COG1160 Predicted GTPases  ali follow..  15  55....VIDTGG--IDGTEEGVEEKMAEQSLLAIDEADIVLFLVDARAGLTAADIGIANYLRQRQNKITVVVANKTDGIDADSHCAERGVTQLMEQVLAPFAEKMENADENDRTSALIDDALDEELEEEQDKNIKIAIVGRPNVGKSTLTNRILGEDRVVV----------------FDMPGTTRDSIYIPMERDGQQ-----YTLIDTAG----VIKTLQAIQDANVVLLTIDARENISDQDLSLLGFILNAGRSLVIVVNKWDGLDQDVKDRVKS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 349
33 -12.000[P] COG0370 Fe2+ transport system protein B  ali follow..  11  5....................................................................................................................................TYCILGNPNTGKTSLFNAL---TGSYEYVGN----------------GVTVEKKVGTL-------RSKTGKLIDLPGIYDLSRDETVVTRFLDCMLNIVDSSQ--IERNLNLTVQLLEYGAPVVMGLNMIDVAAGRIHLNIQNLAKKLRIPILPVVA--GTEDILSTLSEKHVAPAIPLVLQYGEPAEKAIKEIQALTKELIPAKQSRWLAQFLSKNEVTEAFLTSNSAFEQLQQIRAELESHFHQVRASYIHDICLTSVEYTRNSDIPLSDKLDKIFTHK-GIPIFLGIMWLIFQITFTWVGAPLSDMLDGF-LTTIGASGFIIDLVADGIIAGVGGVLVFVPQILVIFFFISVLEDSGYMARIAVVMDRVMEGCNVPGIMAARSIEESKE-RTLTILVSPFMSCSARLPVYALFVGVFLYVIGILMALIVTKILSKTIKKDNSVFVVELPPYRLPSLKTLWRSTWEKGKGFLRKAGTFIFAGSVIIWLLDVPMGESFLAIIGGM-LAPLLVPLGFGTWQAGATLIPGFLA-KEVVVSTMAIIYAVGESSLGSIVSTFYTPL........................................................................................................................................................................................................................................................................................ 606
34 -11.800[U] KOG0077 Vesicle coat complex COPII, GTPase subunit SAR1  ali follow..  16  18................................................................................................................................QKEAKILFLGLDNAGKTTLLHML-------------------------KDERLVQHQPTQHPTSEELSIGKIKFKAFDLGGHQIARRVWKDYYAKVDAVVYLVDAFAESKRELDALLSDEALATVPFLILGNKIDIPYA---ASEDELRYHLG...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 147
35 -11.700[U] KOG0096 GTPase Ran/TC4/GSP1 (nuclear protein transport pathway), small G protein superfamily  ali follow..  15  14....................................................................................................................................KLVLVGDGGTGKTTFVKRHLTGE----------------EKKYIATIGVEVHPLSFYT-----NFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDLVRNIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISA.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 153
36 -11.700[R] KOG0080 GTPase Rab18, small G protein superfamily  ali follow..  16  1...........................................................................................................................MDEDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATI---------------GVDFKVKTISV-----DGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFAR........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 141
37 -11.500[R] KOG0075 GTP-binding ADP-ribosylation factor-like protein  ali follow..  19  22....................................................................................................................................ELTLVGLQFSGKTTFVNVI------------------------ASGQFAEDMIPTVGFNMRKITRGNVTIKVWDIGGQPRFRSMWERYCRGVNAIVYMVDALEASRNELHSLLDKPQLAGIPVLVLGNKRDLPGA---LDETGLIERMN...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 148
38 -11.400[U] KOG0076 GTP-binding ADP-ribosylation factor-like protein yARL3  ali follow..  19  19....................................................................................................................................SILILGLDNAGKTTFLETL----------KKEYSLAFKALEKIQPTVGQNVATIPVD--------SKQILKFWDVGGQESLRSMWSEYYSLCHGIIFIVDSLDECSTTLQSVVMDEEIEGVPILMLANKQDRQDR---MEVQDIKEVFNKIAEHIS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 158
39 -11.400[R] COG1159 GTPase  ali follow..  16  1...........................................................................................................................MSTDKTYCGFIAIVGRPNVGKSTLLNKLLGQKISITS-----------------RKAQTTRHRIVGIH----TEGPYQAIYVDTPGNRLMNKAASSSIGDVELVIFVVEGTRWTP-DDEMVLNKLRDGKAPVILAVNKVDNV...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 129
40 -11.300[R] KOG0394 Ras-related GTPase  ali follow..  13  1...........................................................................................................................MPSRRRTLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATI---------------GADFLTKEVQF-----EDRLFTLQIWDTAGQERFQSLGVAFYRGADCCVLVYDVNSMKSFENLNNWREEFLENFPFVLIGNKVDVDDGNSRVVSEKKAKAWCASKGNIPYFETSAKVGTNV................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 165
41 -11.100[R] KOG0074 GTP-binding ADP-ribosylation factor-like protein ARL3  ali follow..  19  19....................................................................................................................................RILLLGLDNAGKTTLLKQL-------------------------ASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSFEETGQELAELLEEEKLSCVPVLIFANKQDLLTA---APASEIAEGLN...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 144
42 -11.000[V] KOG1707 Predicted Ras related/Rac-GTP binding protein  ali follow..  10  8............................................................................................................................SSGSPKPIRIVVVGEKGSGKSSLIMAAARNT--------------------HPNIPSLLPYTNLPS---EFFPDRIPATVIDTSSRPEDKGKVVKEVRQADAIVLTFATLDRLSKYWLPLFRQL-EVRVPIIVAGYEVDNKEAYNHFSIEQITSALMKQYREVETSIQWSAQRLDQA-------KDVLYYAQKAVIDPVGPVFDQENNVLKPRCIAALKRIFLDGILSDEELNELQKKCFDTPLVPCEIKQMKNVMQVTFPQGVNERGLTLDGFLFLNTRLIEEARIQTLWTMLRKFGYSNDLRLGDDLVPYSSFKRQADQSVE-EFFDSNGDNNLEPHEMGYLFETAPESPWTKPLYKDVTEENMDGGLSLEAFLS-PSDDPSSAVRVTRKRVLDRKEKKSERKVVQCFV--------FGPKNAGKSALLNQF-SDTDKTLVLKEVRIKDDGFMLSKEALAACDVAIFIYDSSDEYSWNRAVDMLAEVAKTDLDPFPVAIQESTRVTQDIG-IPISSKLGDVSNLFRKILTAAENPHLNIPEIESKKKRSCKLNNR...................................................................................................................................................................................................................................................................................................... 620
43 -10.900[U] KOG0081 GTPase Rab27, small G protein superfamily  ali follow..  21  7................................................................................................................................DYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVG----IDF----REKRVVYRASGPD---ATGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTLNVRNWISQLQMHAYCENPDIVLCGNKSD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 136
44 -10.900[UZ] KOG0073 GTP-binding ADP-ribosylation factor-like protein ARL2  ali follow..  15  18....................................................................................................................................RLLMLGLDNAGKTTILKKF-------------------------NGEDIDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSMQDCQRELQSLLVEERLAGATLLIFANKQDLPGA---LSSNAIREALE...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 143
45 -10.900[H] KOG2743 Cobalamin synthesis protein  ali follow..  18  3............................................................................PAVGSVDEEEDPAEEDCPELVPIETTQSEEEEK---------------SGLGAKIPVTIITGYLGAGKTTLLNYILTEQNESGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDQKKGKFDDILLETTGLADWVDAELGSDIYLDGIITIVDSKYGLKHLTEEKPDGLINEATRQVILINKTD-------LVPEEDVKKLRTTIRSINGLGQILETQRSRVDLSNVLDLHAFD...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 249
46 -10.700[TU] KOG0084 GTPase Rab1/YPT1, small G protein superfamily, and related GTP-binding proteins  ali follow..  17  1...........................................................................................................................MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDSYLDSYISTI---------------GVDFKIRTVEQ-----DGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVTYDVTDLESFNNVKQWDRYASENVNKLLVGNKCD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 124
47 -10.700[U] KOG0071 GTP-binding ADP-ribosylation factor Arf6 (dArf3)  ali follow..  17  23....................................................................................................................................RILMLGLDAAGKTTILYKL-------------------------KLNQSVVTIPTVGFNVETVTYKNIKFNVWDVGGQDKIRPLWRHYFTGTKGLIFVVDSISEARQELHRIISDREMRDCLLLVLANKQDLPGA---LSPAQITDVLQ...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 148
48 -10.700[R] COG1100 GTPase SAR1 and related small G proteins  ali follow..  17  6......................................................................................................................SSMFDKLWGSNKELRILILGLDGAGKTTILYRL-------------------------QIGEVVTTKPTIGFNVETLSYKNLKLNVWDLGGQTSIRPYWRCYYADTAAVIFVVDSMSTASKELHLMLQEEELQDAALLVFANKQDQPGA---LSASEVSKELN...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 145
49 -10.700[U] KOG0070 GTP-binding ADP-ribosylation factor Arf1  ali follow..  16  19....................................................................................................................................RILMVGLDAAGKTTILYKL-------------------------KLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSVVEARDELHRMLNEDELRDAVLLVFANKQDLPNA---MNAAEITDKLG...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 144
50 -10.600[U] KOG0072 GTP-binding ADP-ribosylation factor-like protein ARL1  ali follow..  15  19....................................................................................................................................RILILGLDGAGKTTILYRL-------------------------QVGEVVTTIPTIGFNVEQVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSIGISKDELLYMLREEELAGAILVVLANKQDMDGC---MTVAEVHHALG...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 144
51 -10.500[R] KOG1533 Predicted GTPase  ali follow..  14  1..................................................................................................MQMNLNEKKQLLRVRVYATSEKGENLGSTHWTMYGVLVIGAPGAGKSTFCAGLTDIFSQTKRP-DVNITEMITVNDVMDRLGLGPNGALKYCIETLGANCNWLLQIIDCPGQLELYKSEGELWKVIR-ALHLADSLSKFISVALSTLATMVTMEMPQVNCLSKADLF...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 207
52 -10.500[T] KOG4252 GTP-binding protein  ali follow..  16  2...........................................................................................................................LEEDMEVAIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTI---------------GVDFLERQIQV-----NDEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRGSFEAVSSWREKVVADIPTVLVQNKID........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 124
53 -10.500[T] KOG3886 GTP-binding protein  ali follow..  11  1..................................................................................MEESDSEK---------TTEKENLGPRMDPPLGEPEGSLGWVLPNTAMKKKVLLMGKSGSGKTSMRSIIFADTRRLGATILDRIHSLQINSSLSTYSLVDSVGNTKTFDVEHSHLGNLVLNLWDCGGQDTFMENYFTSFRNVEVLIYVFDVESRELEKDMHYYQSCLEADAKIFCLVHKMDLVQEDQRDLIFKEREE........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 207
54 -10.400[R] KOG1490 GTP-binding protein CRFG/NOG1 (ODN superfamily)  ali follow..  20  155.....................................................................................................................RQHMARLPSIDPNTRTVLICGYPNVGKSSFMNKVTRADVDVQP--------------------FTTKSLFVGHT----DYKYLRYQVIDTPGILDRPFESITALAHLRAAVLFFSGSCGYTIAQQAALFHSIKSLFPLVIVCNKTD-------MPMENISEEDRKLIEEMK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 311
55 -10.400[U] KOG0095 GTPase Rab30, small G protein superfamily  ali follow..  18  3............................................................................................................................MEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATI---------------GVGFMIKTVEI-----NGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWEQYASNKVITVLVGNKID........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 125
56 -10.400[TU] KOG0078 GTP-binding protein SEC4, small G protein superfamily, and related Ras family GTP-binding proteins  ali follow..  20  4.............................................................................................................................KSYDYLIKLLLIGDSGVGKSCLLLRFSEDSFTPSFITTI---------------GIDFKIRTIEL-----DGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLLYDVTDKKSFDNVRTWEQHASENVYKILIGNKCD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 125
57 -10.400[U] KOG0086 GTPase Rab4, small G protein superfamily  ali follow..  19  1...........................................................................................................................MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTI---------------GVEFGSRVVNV-----GGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWRTLASPNIVVILCGNKKD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 124
58 -10.300[R] KOG1673 Ras GTPases  ali follow..  15  103....................................................................................................................................KISLLGDCQTGKTTFVVKYVGDE----------------NQSFLEMTGLNLMDKTFYV-----QGVTISFSIWDVGGD--SKDHIPIACKDAVAILFMFDLTSRSTLNSVFGWYSQARKTAIPILIGTKFDRLPPNLQWTIVTQARAYAKVMNASLFFSSATHNINVNKIFKFILARL......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 266
59 -10.200[U] KOG0093 GTPase Rab3, small G protein superfamily  ali follow..  20  20................................................................................................................................DYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTV---------------GIDFKVKTIYR-----NDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWKTYSWDNAQVLLVGNKCD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 138
60 -10.200[R] KOG0091 GTPase Rab39, small G protein superfamily  ali follow..  17  7................................................................................................................................EYQFRLILIGDSTVGKSSLLKFFTDGKFAELSDPTV---------------GVDFFARLIEM----KDGTQIKLQLWDTAGQERFRSITKSYYRNSVGVLLVYDISEHIPLWMMEAQRHIEPHRPVFALVGCKLDLINAGGHREVT............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 138
61 -10.100[U] KOG0094 GTPase Rab6/YPT6/Ryh1, small G protein superfamily  ali follow..  17  11....................................................................................................................................KLVFLGDQSVGKTSIITRFMYDKFDTTYQATI---------------GIDFLSKTMYL-----EDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDVANRLSFLNTSKWRNERAGDVIIVLVGNKTD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 125
62 -10.100[U] KOG0092 GTPase Rab5/YPT51 and related small G protein superfamily GTPases  ali follow..  17  22....................................................................................................................................KLVLLGESAVGKSSLVLRFVKGQFHEFQESTI---------------GAAFLTQTVCL-----DDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWQRQASPNIVIALSGNKAD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 136
63 -10.100[R] COG1163 Predicted GTPase  ali follow..  11  9............................................................................KAIEDEMARTQKNKATSFHLGQLKAKLAKLRRELLTSASSGSG--IGFDVARTGVASVGFVGFPSVGKSTLLSKLTGTESEAAEYEFT-----------------TLVTVPGVIRYKGAK-----IQMLDLPGIIDGAKDVIAVARTCNLLFIILDVNKPLH-HKQIIEKELEGVGIPPDILIKKKEKGGISITNT............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 195
64 -10.100[U] KOG0097 GTPase Rab14, small G protein superfamily  ali follow..  16  1........................................................................................................................MATAPYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTI---------------GVEFGTRIIEV-----SGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWRNLTNPNTVIILIGNKAD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 127
65 -10.000[R] KOG0088 GTPase Rab21, small G protein superfamily  ali follow..  19  1.......................................................................................................................MLETNVDQKSFKFKIVLLGEGCVGKSSLVLRFVENKFSCKHLSTI---------------QASFQNKTVNV-----EDCQADLHIWDTAGQEKYHALGPIYYRGSNGVLLVFDITDRKSFEKVKNWKTCLGNTAEILIVGNKID........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 128
66 -9.950[R] KOG0079 GTP-binding protein H-ray, small G protein superfamily  ali follow..  16  8................................................................................................................................DHLFKLLIIGDSGVGKSSLLLRFADNTFSENYITTI---------------GVDFKIRTMDI-----NGQRVKLQIWDTAGQERFRTITSTYYRGTHGVVVVYDVTNGESFGNVKRWLQEIENSVQKVLVGNKCE........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 125
67 -9.890[K] KOG1534 Putative transcription factor FET5  ali follow..  13  8.......................................................................................................................................VCGVASSGKSTFCGALMSYMKSVGRS-TVDIRDLISIDDVMEELDYGPNGGLIYCFEFLMENLDWLNEIFDMPGQIELYTHVPILPALIR-AVYLLESQTKFFAGVLSAMSAMVMMEVPHINLLSKMDLL...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 178
68 -9.860[U] KOG0087 GTPase Rab11/YPT3, small G protein superfamily  ali follow..  16  8................................................................................................................................DYLFKTVLIGDSGVGKSNLLMRFTRNEFNIESKSTI---------------GVEFATRNIVL-----DNKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDITKQSSFDNVGRWREHADSNIVIMLVGNKTD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 126
69 -9.790[OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase  ali follow..  13  2................................................................................................................................KRPLIIGVGGPVGAGKTMLIERLTRY---LSTKGYSMAAITNDIYTKEDARILSMNFAAIEEMCDKHPDLQLL--FLESGGDNLSATFSPD---LVDFSIYIIDVAQG----EKIPRKGGQGMIKSDLFIINKVD-LAPYVGANVEVMKADTLKSRGNKDFFVTNLKTDEGLKSV................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 191
70 -9.730[U] KOG0098 GTPase Rab2, small G protein superfamily  ali follow..  19  4................................................................................................................................AYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTI---------------GVEFGARMVTI-----DGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTSWRQHSNSNMVIMLIGNKSD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 122
71 -9.610[T] KOG1486 GTP-binding protein DRG2 (ODN superfamily)  ali follow..  15  8............................................................................KEIEAEMARTQKNKATEYHLGQLKAKIAKLRTQLLEPPKGASGGGEGFEVTKYGHGRVALIGFPSVGKSTLLTMLTGTHSEAAS--------------------TTLTCIPGVIHYNDTK-----IQLLDLPGIIEGASEVIAVAKSSDLVLMVLDASK--EGHRQILTKELEAVGLPPQIYFKKKKTGGISFNTT............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 192
72 -9.560[T] KOG1487 GTP-binding protein DRG1 (ODN superfamily)  ali follow..  12  62................................................................................................................................TGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFT-----------------TLTTVPGVIRYKGAK-----IQLLDLPGIIEGAKDVIAVARTCNLILIVLDVLKPLG-HKKIIENELEGFGIPPNIGFKKKDKGGINLTAT............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 194
73 -9.280[R] COG0523 Putative GTPases (G3E family)  ali follow..  18  2................................................................................................................................TPIAVTLLTGFLGAGKTTLLRHILNEQHIENEFGEVSVDDQLIGDRATQ-SNELEDALLDLLDSRDRGDIAFDRLVIECTGMADFSHDVLCERYLLDGVIALVDAVHANE-QMNQFTIAQSQIGYADRILLTKTDVA---------GDSEKLRERLARINARAPVYTVVHGDIDLS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 193
74 -9.070[DZ] COG5019 Septin family protein  ali follow..  20  97....................................................................................................................................NVLVLGESGSGKSTLVNTLLNRD-------PPTQKSLTGDFGVNPEPTVMINSSAVEI---VENGISLQLNVIDTPGFGDYLELEKHNPRIQDPCIFFIQPTGHAISAMELRVMLALHEKVNIIPIIAKADTLTDD---ELNFTKEMILRDIQYHNIRI............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 271

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.