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Query: [B] KOG0639 Transducin-like enhancer of split protein (contains WD40 repeats), from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFPQSRHPTPHQAAGQPFKFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELNAIIGQQQLQAQHLSHGHGPPVPLTPHPSGLQPPGIPPLGGSAGLLALSSALSGQSHLAIKDDKKHHDAEHHRDREPGTSNSLLVPDSLRGTDKRRNGPEFSNDIKKRKVDDKDSSHYDSDGDKSDDNLVVDVSNEDPSSPRASPAHSPRENGIDKNRLLKKDASSSPASTASSASSTSLKSKEMSLHEKASTPVLKSSTPTPRSDMPTPGTSATPGLRPGLGKPPAIDPLVNQAAAGLRTPLAVPGPYPAPFGMVPHAGMNGELTSPGAAYASLHNMSPQMSAAAAAAAVVAYGRSPMVGFDPPPHMRVPTIPPNLAGIPGGKPAYSFHVTADGQMQPVPFPPDALIGPGIPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIYLast
1 -192.000[B] KOG0639 Transducin-like enhancer of split protein (contains WD40 repeats)  ali  100  1MFPQSRHPTPHQAAGQPFKFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELNAIIGQQQLQAQHLSHGHGPPVPLTPHPSGLQPPGIPPLGGSAGLLALSSALSGQSHLAIKDDKKHHDAEHHRDREPGTSNSLLVPDSLRGTDKRRNGPEFSNDIKKRKVDDKDSSHYDSDGDKSDDNLVVDVSNEDPSSPRASPAHSPRENGIDKNRLLKKDASSSPASTASSASSTSLKSKEMSLHEKASTPVLKSSTPTPRSDMPTPGTSATPGLRPGLGKPPAIDPLVNQAAAGLRTPLAVPGPYPAPFGMVPHAGMNGELTSPGAAYASLHNMSPQMSAAAAAAAVVAYGRSPMVGFDPPPHMRVPTIPPNLAGIPGGKPAYSFHVTADGQMQPVPFPPDALIGPGIPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY 770
2 -82.700[D] KOG0642 Cell-cycle nuclear protein, contains WD-40 repeats  ali follow..  10  31...AAAGDGAAAAGAARAQYSLPGIL-------HFLQHEWARFEVERAQWEVERAELQAQIAF-------LQGERKGKKDLVRRIKMLEYAL------KQERAKYHKLKYGTELNQGDMKPPSYDSDEG------------------------------------NETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALLGFSIDVTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESAAADFSDEDEDDDVDGREKSVIDTSTIVRKKPDSGEDRDTKEALKEFDFLVTSEEGDNESRSAGDGTDWEKEDQCLMPEAWNVDQGVITKVKRPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSGKSFIMGADEAL-------ESELGPGELAGLTVANEADSLTYDIANNKDALRKTWNP-----KFTLRSHFDGIRALAFHPIEPVLITASDHTLKMWNLQKTAPAKKSTIYTFRAHKGPVLCVVMSSNGEQCYSGGTDGLIQGWNTTNPNSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVKELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLNSSCQINRVISHPTLSISITAHEDRHIKFYDNNTGKIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEKKFEESIHDVAFHPSKCYIASAGADALAKVF.... 779
3 -75.100[A] KOG0306 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  13  51............................................................................................................................................................................................................................DLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAYLQEIKKIKGSSPGIQDTLEAEDGAFETDEAPEDRILSC--RKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLELFCILSKKEIITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTM-------TCEYALCSFFVPGDRQVVIGTKTGKLQLYDLA--SGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHITLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERT. 705
4 -75.000[A] KOG0291 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  2...........................KFSYKFSNLLGTIYRNG-DGNSVISPVGN-----ITVYDLKNNKSRTLSLESR----------YNYTNIALSPDGSLLIAVNEKGEAQLISMMS-------TVIHRHKFQTGVQCICFSPNGAFFAVAVQNVVLIFCAPGEITGEYNPFVLRRRFLGGFDDVTWLDWSSDSR-------AIGCRDSSTKIVAINYTKNFRTYNLSGHTDAIVACFFEANSLHLNTISRNGQLCLWECSLAPSDL-EDAERPKIAPPQRKKEKKAVSDNESEDDVENVVEKDALKEESTKEAEDVNHIKNEDETKSHPFFYKKITRHYLADEPR-----KEQRDVQLTAANYNTRTKVLVVAFSSGAFYLYELPDVNMIHSLSISDYPISAALFNCTGDWVALASREILVWEWQSEQYIMKQQGHSSEMTCIAYSSDGQFIATGGEDSKVKLWNTQSSFCFVTFSEHTSGVTGIQFSRNKKFLVSSSDGTVRAFDVNRYRNFRTF----TSPNPAQFSCVAVDYSGELVVAGGQDVDIFLWSVK--TGKLLEIISGHEGPVVSIAFSPTSSTLVSGSWDKTVKIWNCLESNSEHETIDAVSDVTNVTFSPSGEEIAVATLSGNITIFDIKSAGQVTTIEQANYFSTIEYSADGECILAAGKSANICIYHVREAILHSLDGLNDFISRKHLSEFGNMALVEGGRVAIRLPGVQRGDMSRRFQQEVRVFSVKFSPTGQAFAAAGTEGLCIYA.... 752
5 -74.300[A] KOG0319 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  12  44..........................................................................................................................................................................................................................DLADNTASYTIGDPEDELRITCTAVDKNRNRLLVAYNNQIIREYSIPLDPSTTKKTIHTAPILVMEFNEEGHLLATGSADHIVKVWNLTEQQCTHTLKGPSVVSAILFGKHEKLVVGYIEGQLNNIMRGAPKKLVNTWKSHNSHITALLQVPDSRVVVALSRDQTMSIHETETQETLRVLPLYES-IEGGAIGHNGNLFTVGEEGVKEFVIETAKLVRKKRIASSNLDHLAYDVVSNRFLAISAEQNLIILDFENLKIARQIVGHDEIYSCCLLGKDESHMAVASTSEIRLYNTKTLD-----CQLIRGHTESVLSVVSPTWDTSLLASCSKDNSIIFWRLVTSTLVPVAAATGHANTVTALAISNTGRFLASVSTDCTIKLWGLGKLTCSSTMVAHGKDVNCVDISESDALIATGGMDKLVKLWQVDTHKMQLGIGHRRGVGDVKFAKNSHKLASCSGDMTIKIWNISEKSLQTISGHSCAVFRVIFARNDSQLISADSAGIIKIWTIKTADCESIDAHTDKIWSLSKNHNESEFVTAGTDGRIVVWKDV. 637
6 -74.000[S] KOG0271 Notchless-like WD40 repeat-containing protein  ali follow..  14  3......................................................................................................................................................................................................................................................................................................................................................................ESPQISVSFVSEDENELGGSGILVPVDISTNELQILNQLLGSSDDPVPISFFTTEGAEIVDSIRKSLERVRPVTRCSASIPGHGEPVISAQFSPDGRGLASGSGDQTMRIWDIELELPLHTCKSHKSWVLCIAWSPDATKIASACNGEICIWNAKTGEQIGK----TLKRHKQWITSLAWQPTCRLLASCGKDGNIFIWDTV--QGTVVRCLSGHTASVTCLRWGGEGL-IYSGSQDRTVKMWRADDGVMCRNMTGHAHWINTLALNTDGERLVSGSDDFTLFMWNPKETKQSRMTGHMQLVNQVVFSPDTRYIASASFDKSVKLWCGRTGKLASLRGHVGPVYQVAWSADSRLLVSGSADSTLKVFELKTKSLYDLPGHGDEVFTVDWSPEGTKVVSGGKDKVLKLWR... 472
7 -73.200[S] KOG0295 WD40 repeat-containing protein  ali follow..  18  20...............................................................................................................................................................................................................................................................................................................................................................................................................QNNGYSESFSVFLKESSLSENDIKPLILEKKWTTVLRLQRKVNDLESKLQESQREINHGAPTRDKRQAADWIPRPPETQKLTGHRLPITRVIFHPLWTIMASCSDATIKVWDYETGQLER-----TLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFGQ-TYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVYTFRGHNDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLDHEHAVECVEWAPDTAYLFSGSRDRSIKAWNINTGDLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWELSAQRCMAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVWEC.. 403
8 -71.400[Z] KOG0318 WD40 repeat stress protein/actin interacting protein  ali follow..  10  10.............................................................................................................................................................................................................................ENKNIYATLPRTQRGQPIVLGADPKGKNFLYTNGN-SVIIRNIENPAIADVYTEHSCAVNVAKYSPSGFYIASGDASGKIRIWDTVNKEKNEFQPIAGPIKDISWSPDNQRIVAVGEGRFGHVFMSETGTSVGEISGQSKSINSADFRPARPRIVTGSEDNTIAVFEGPPFKFKMTKQDHSRFVQAVRYSPDGKFFASAGFDGKVFLYDGTSGEFGSPAHKGGVYALAWKPDSTQLLTCSGDKTCRLWTVESRELVSEFVGTTVDDQQVSCLWQGDNLITVSSGVITYLNVADPSK----PLRVVKGHNKPITVLGLSDDRSTIYTGSHDGVVTNWNSGSGT---NDRITGTGHGNQINGIAAWGDFVYTCGIDDSLRQFSVEGNSYTDYVVKLNCQASSIAVNADTSDVAVGGDDQKLHIYTLKGGVLEPKVDHLGAVTDVSYSPDLKYLVACDAHRKVVLYSVEEYKPAEWGFHSARVNTVAWSPNSLLVASGSLDTTIIIWSVANPAKHIKNAHPQSQITRLVWLDNNTVISTGQDCNTKVWHV.. 605
9 -69.800[A] KOG0285 Pleiotropic regulator 1  ali follow..  17  2...............................................................................................................................................................................................................................................................................................................................................................................................IALNREVETQSLKKLSLKSVRRAREIFSPVHGQFPQPDPESKRIRLTRIADHNSEKTAPLKALALPGPKGSKELRKSATEKALVVGPT-LPPRDLNNTGNPGKSTAILPAPGSFSTAALMERMPSRWPRPE--HAPWKNYRVLQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVA--TGVLKLTLTGHIGQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKVIRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVWDIRTKMQIFVLPHDSDVFSVLARPTDPQVITGSHDSTIKFWDLRYGKSMTITNHKKTVRAMALHPKENDFVSASADGGLWFWDWKSGHNFQSLESEAGIYAACYDQTGSRLVTCEGDKTIKMWKE.. 455
10 -69.400[K] KOG0263 Transcription initiation factor TFIID, subunit TAF5 (also component of histone acetyltransferase SAGA)  ali follow..  10  2.......SATNGPQPQDLNRIVLDYLAKYSRTEAMLRLEASSVEEKLKSIEETPDAYTHTYTILRDWVDS-SLELYK-AELHRILFPIFVHSLNLLSQDHYEAAKQFYELLHDFDVKNLKSLSLPSHVAEDRTAQQ---------------------------------------------------------------------------------RQNKYQLHFSRITFDLLLHFLFENVSNGGSIIIKLINQHIDIHIVPGRPT----------------------------------------------VLENAKVINEQEGITGQSFERGDAQLQPVKLQQMPMDKEMEKIVEMDLEEEDMMHQNDPNNQSPKLLKEFRKLHEPNAEDAPSRDYIPLPPHKGVDILSEVEAVKDWSKRLHLGPRASLPSVYTFHHTNNNMNCAEFSPDSTMIACGFQESYIRLWSIKADKKSVRLLSHSGPVYGTTFSPDNKYLLSCSDASARLWSVDTKTALV-----AYKGHTGPVWDVAFGPFGHYFATASHDQTAQLWSCD--HIYPLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCRLWDVHRGHSVRVFNGHTQPVTAVAIAPDGHTMASADSEGLIHLWDIGTGRRIKTMGHRGNIYSLSFSRESTVLVSGGSDCTVRAWDVFKTNNNPVSSSLTGSVVTPFSAKTSTFNE--------VNWSTSPDQMALYTKQTPIFNVSFTRRNLCLAISVS........... 643
11 -68.700[S] KOG0282 mRNA splicing factor  ali follow..  4.....................................................................................................................................................................AIAALAASYGSGSGSESDSDSESSRCPLPAADSLMHLTKSPSSKPSLAVAVDSAPEVAVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRT--------------------------------FATYGYALDPSLDNHQVS-AKYIGSVEEAEKNQGLTVFETGQKKTEKRKKFKENDASNIDGFLGPWAKYVDEK-DVAKPSEEEQKELDEITAKRQKKGKQEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPK-KQIHVWSGHTKGVSAVRLFPLGHLLLSCSDCKIKLWEVYGERR----CLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTE--TGQCISRFTNRK-VPYCVKFNPDEDLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLN-HMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYRFKAHDKVCIGAVWHPETSKVITCGWDGLIKLWD... 579
12 -68.500[R] KOG1539 WD repeat protein  ali follow..  10  14..........................................................................................................................................................................................................................................TSTVPFSVQRLGTETFVTVSVGKAFQIYNCAKKFFLLLKPKLPKKIRALASYRDYTFVAFGNEIAVFR----RAHQVATWSKHVAKVDLLLVF--GEHVLSLDVEGNMFIWAFKGIEEHLALTGKFTPTSIVHPDTYLNKVLVGSQEGPLQLWNINTKKMLYQFKGWGSSVTSCVSSPALDVVAIGCADGKIHVHNIKLDEEIVTASRGAVTALSFSTDGRLLASGGSFGVISIWNLNKKRLQSVIRAHDSSIISLNFLANEPVLMSASDNSLKMWIFDTNDGDPRL-LRFRSGHSAPPLCIRFYSNGRHILSAGQDRAFRLFSVIQEIKGVFVSRNHLLLAILACAISACGNFAVVGTAGGWIERFNLQSGISRGSYYAHDGEVIGVACDSTNTLMISAGYHGDLKVWDFKKRELKSQWDVGCSLVKIVYHRVNGLLATVADDFVIRLYDVVTLKMREFRGHTDRITDLCFSEDGKWVISSSMDGSLRIWDVILAKQIDGVHVDVPITALSLSPNMDVLATAHSDQNVYLWV... 648
13 -68.500[R] KOG0286 G-protein beta subunit  ali follow..  17  2............................................................................................................................................................................................................................................................................................................................................................................................................................................GEMEQLRQEAEQLKKQIADARKACADVTLAEL--VSGLEVVGRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASDGKLIVWDSYTTNKVH-----AIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN... 340
14 -68.400[B] KOG0273 Beta-transducin family (WD-40 repeat) protein  ali follow..  13  16................................................................................................................................................................................................................................................................................LQESGFSHSAFTFGIESHISQSNINGTLVPPSAL---ISILQKGLQYVEAEISINKDGTVFDSRPIESLSLI-----VAVIPDVVQMRQQAFGEKLTQQQASAAATEASAMAKAATMTPAAISQQNPEATVNGEENGAHEINNHSKPMEIDGDVEI--PPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSEGGHDVPSNKDVTSLDWNSDGTLLAMGSDGFARIWTENGN------LASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAH--TGEAKQQFPFHSAPALDVDWQNNMT-FASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLAHSKEIYTIKWSPTGPMLASASFDSTVRLWDVEQGVTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQGTGGIFEVCWNARGDKVGASASDGSVCVLDL.. 522
15 -68.100[R] KOG0288 WD40 repeat protein TipD  ali follow..  12  30...................................................................................................................................................................................................................................................................................LEEGAHAPAISALSKPLISQGSEWKEKTEKLETELQQCYKAQSRLSEQLVIEVAESRTSKAILQEKELL---------NDLQKELTQRREDCTRLQEELEEKTKTVDVLIAENLEIRSQLEEMTSRVQKAETENKMLIDRWMLQKMQDAERLNEANDLYEEMLAKLKANGLETLARQQVDGIVRRNEDGTDHFVESTPSTCANRIHAHEGGCGSIVFEYNSGTLFTGGDRAVKMWDTNSGTLIK-----SLYGSLGNILDMAVTHDNKSVIAATSSNNLFVWDVS--SGRVRHTLTGHTDKVCAVDVSKFSRHVVSAAYDRTIKLWDLHKGYCTNTV-LFTSNCNAICLSIDGLTVFSGHMDGNLRLWDIQTGKLLSEVGHSSAVTSVSLSRNGNRILTSGRDNVHNVFDTRTLEICTLRASGNRLASSCISPDDDYVAAGSADGSVHVWSLSKGNIVILKEQTSPILCCSWSGIGKPLASADKNGYVCTWT... 515
16 -68.000[S] KOG0308 Conserved WD40 repeat-containing protein  ali follow..  14  1................................................................................................................................................................................................................................................................................................................................................................................................................................MSSCVNTSQTGKISFIIRDEHEYSNRSAVSALQYDAQNGRLFTGGSDTIIRTWSVPHHKDQGSLEQHTDWVNDMILCGHGKILISASDTTVKVWNIERDNKHGFID--CIRTHKDYVSCLAYAPIVEKAVSASFDHNIFVYDINA-NFKTVNNLIGCKDSIYSLATTPNLSLVLGAGTEKCIRLFDPRTNEKIMKLRGHTDNVRALVVNDDGTRALSAGSDATIRLWDIGQQRCIATCAHEEGVWTLQVDSSFTTVYSAGKDKMVVKTPLYDFTKQLLFKEEAPVKKLLLSEKDNSLWVGTWKSDIKRWSIRPSAQLLVIPGAPAIKKHAMLSDKRHVLTRDSDGNVALYDVL. 421
17 -67.800[A] KOG0640 mRNA cleavage stimulating factor complex; subunit 1  ali follow..  13  2.................................................................................................................................................................................................................................................................................................................................................................................RDEILDPSNLVKNREILYRLMISQL--MYDGLEKFAMELSMLVKADQCAPSERLLHVMIATLSDKDKTNSDDVLPGIDLEFEPEASALAPEPHSYETA-----------YVTSHKQACRAGAFSCDGSLVATGSDASIKILDVERMEQQGHPVIRTLYDHTDEVSYLEFHPKEHILASASRDGTVKLFDIAKPSVKKAHKVFTDCEPVLCLSFHPTGDYVAIGTEHNVLRVYDVATTQCFVSAQQHKAGVTCVKYSPTGKLYATGSYDGDIKIWDGISGRCINTIHGGAAICSLEFTRNGKYLLSSGMDSLVYLWELCTSRPIQTGKQEHQTEAVFNHTEDYVLFPDEATTSLCSWNSRNGCRLNSLGHNGPVRYITHSPNGPAFLTCSDDFRARFWYR.. 419
18 -67.700[S] KOG0772 Uncharacterized conserved protein, contains WD40 repeat  ali follow..  13  2..................................................................................................................................................................................................................................................................................................................................................................................DDNTAPKKNSEKKARVFDLQNAPRTEEPTHVPQSVSVSSKSESGVSSSAVSDDEDDFMPDLPPGFQMQQSEAGPSSSRAEGPEDSDDSDFDETEAISIIKLIPAACEAKISHGTQAISALRVEPPGVRFASGGDYYVKLFDFQKMDMSMRYDKELLPAESHVINSLAFSPNGETLVVASGEAIIRLLDRAGKQ-IDLNITKGHTATVNCVEFNPLNKEFISCSDDGSLRLWNLDDHKVIKGANGKRVSPQVCTFSPDGKWIAAGCDDGSVQAWKYGSQYVNVNYAHNGSITSIAFSPDSKRLLSRGFDDTLKMWSLDNPKEKTGLENAFKSTDCGFSPRAEVVFTGDTPGTLQFFDPMTFDLVKIDYPGISCHRIQWHPRLNQIIAGLSDGTIHVYY... 446
19 -67.300[D] KOG0267 Microtubule severing protein katanin p80 subunit B (contains WD40 repeats)  ali follow..  12  1...................................................................................................................................................................................................................................................................................................................................................................................................................................................MSLCGHTSPVDSVAFNSEEVLVLAGASSGVIKLWDLEESKMVRAFTGHRSNCSAVEFHPFGEFLASGSDTNLRVWDTRKKGCIQ-----TYKGHTRGISTIEFSPDGRWVVSGGLDNVVKVWDLT--AGKLLHEFKCHEGPIRSLDFHPLEFLLATGSADRTVKFWDLETFELIGTTRPEATGVRAIAFHPDGQTLFCGLDDG-LKVYSWEPVICRDGVDMGWSTLGDFCINEGKFIGCSYYRNSVGIWVSDISELESEDKNECMVKRFSVLNDQSERMGSGPRGSVSP-----------DYETREIKNIYVDSTGGNLNVAQNPGSLKATLPL. 321
20 -66.100[U] KOG0276 Vesicle coat complex COPI, beta` subunit  ali follow..  12  2....................................................................................................................................................................................................................................................................................................................................................................................................PLRLEIKRKLAQRSERVKSVDLHPTEPWILASLYSGTLWNYQTQVMAKSFEVTELPVRSAKFVARKQWVVAGADDMYIRVYNYNTMDKVKVFEAHSDYIRCVAVHPTLPYVLSSSDMLIKLWDWEKGWA----CTQIFEGHSHYVMQVTFNPKDNTFASASLDRTIKIWNLG--SPDPNFTLDAHQKGVNCVDYFTGGDYLITGSDDHTAKVWDYQTKSCVQTLEGHTHNVSAVCFHPELPIIITGSEDGTVRIWHATTYRLENTLNGLERVWAIGYIKSSRRVVIGYDEGTIMVKLGREIPVASMDNTGKIIWAKHNEIQTANIKSIGADYEVTDGERLPLSVKELGTCDLYPQSLKHNPNGRFVVVCGDGEYIIYTAL.. 382
21 -65.600[S] KOG0296 Angio-associated migratory cell protein (contains WD40 repeats)  ali follow..  15  1....................................................................................................................................................................................................................................................................................................................................................................................................MAEEEENQELYIAENEVEEVKLMDQGVTEDEAEQEQNMNNMVMDMSVQGFFEHKDSVFSVSINPVHNLCASGGGDDLGYIWDITTGEQICQLTGHKDSIVAIDWSFDGTYIATGGDSQVRLWKSSTGFEF-----ITAFETVDEIVWLSWHPKGLFLAAGCNDGSIWMWSLP--SGKVVQVMYGHTAPVNAGKFIPPGKRLATVDDSGTLIVWNPATGAPECRMSETAAGWTSFDCNAEGNVLFLGGSSGKVKVVNINSSHILASLAQTESVEAIALCTALPICACASVDGTVALYDSASLKFRKSLPHEQAVIDCKFLPNTPYLLTACADCVIRKWDVRSGQLLEYTGHQEPILCMAITPDGKRVVTGSDDTELLVFDC.. 397
22 -65.500[R] KOG0315 G-protein beta subunit-like protein (contains WD40 repeats)  ali follow..  12  3..........................................................................................................................................................................................................................................................................................................................................................................................................................DQQQLILATGGYDHTIKVWQAHTGNCIKTVETSQVNALDRTPDKTRLAACG-YQCIRLYDLESNCPVINFDGVQKNVTRLGFQEDGNWMFTAGDHHVRIWDMIAAPPHCS----RIFDCEAPVNAACLHPNQVEIAMGSQNGSVFLWDVK--SERHERIVPEVDASIQDVAISPDGRYLAAANNKGNCYIWSLTSQRPNRKIPAHSRYILRCKFSPDSRLLLTTSGDGTVCIWKTDDFSKWRELIENYWVWDAAFSADSKWLFTASSDGIARLWKLQTKSIRDYTGHTKAITALSFKDEIPVKSTNISDVQSSAKPPTQRD-----NPPGTNNLAFFETVGRVAMNPYMGNTTTELN... 362
23 -65.500[S] KOG0283 WD40 repeat-containing protein  ali follow..  11  2..............................EDGNKLDRK-KTMTMNWEGLGDFEDEDDDRFF-----------------ETHDRLSSALTFDMANASSSDEDEDFDDCRLSFSSAVSSLTTASRKFRTPAMSPDYD-------MAAPGSISERRRRLLHGMG----ASNKDMVSAVSIRRVVSNAPVVSNGEEKKMKKKMNHEVDEQDHDHVPVMLARSRSESDIERFLIEKRRKEEILGKISKQRLTRTYSTICPTRTRICQYQTPIRQTPAVCGNGKALRGGGEALTSVMSNARAFFLIKNLDTGKEFIVNEYDEDGMWNRLSDLQTGKQLTL------------------------EEFEKCVGYSPVVKELMRRENVNRINY--------------EPLMDLRKFNSYLSKSVRLSKRRGAALLKNAHSMSLRVADKDVSDGSTDSPKKGKDHKHGKANEWVKVRELSALHMCQEIQAHEGAVWTIKFSQDAHYLASGGDRVIHVWEVQECELMS-----MNEGSLTPIHPSLCDSSGNEITVVEKKKKGKGSSGRRHSDKPVCSLKGHLDAILDLSWSKSQL-LLSSSMDKTVRLWDIETKTCL-KLFAHNDYVTCIQFSPDENYFLSGSLDAKIRIWSIQDRHVVEWSDLHEMVTAACYTPDGQGALIGSHKGICRAYDTEDCKLSKKSQAKRKITSFQFSPVNPEVLVTSADSRIRILDGSEVIHKFKFRNTCSQLSASYSQDGKYIICASEDSQVYLWKN.. 711
24 -65.400[S] KOG2106 Uncharacterized conserved protein, contains HELP and WD40 domains  ali follow..  11  2..............................................................................................................................................ALCYQRYLLALYHPPPGSGKILLCQQPKVTSRG-PALLNECLLGVEGKAMGIPEETGIAQAPPAALPVAKKNSESKPKEPVFSAEEGYVKLFLRGRPVTMYMPKDQVDSYSLEAKVELPTKRLKLEWVYGYRGRDC-RNNLYLLPTGETVYFIASVVVLYNVEEQLQRH--YAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPH-GIGFFDRAVTCIAFSKSNGGTNLCAVDDDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGEITSLLLDTRRKLPLIRRKAKVVLCVTFSENGDTI-TGDSSGNILVWGKGTNRISYAVQAHEGGISPLCMLRDGTLVSGGGDRKLISWSGNYQKTLSGDFTPITQGHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGHR---PVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRIYGGHSSHVTNVDFLCEDSHLISGGKDTSIMQWRVI. 717
25 -64.900[A] KOG1272 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  12  1...................................................................................................................................................................................................................................................................................................................................MEISSEDNNLMEKVLPPVEQVLTWTLIQICMQESDVELETKVKKYLRGEGANLETLKDKKLKTQLASREKLYGKSAKAAAKIEKWLLPAEAGYLETEGLEKTWVDILSSRNQYDIVLPDFGPYKLDFTASGRHMLAGGRKGHLALLDMMNMS-LIKEIQVRETVRDVAFLHNDQFFAAAQKKYAYIYGRDG-------TELHCLKERGPVARLRFLKNHFLLASVNMSGQLHYQDVT--HGGMVASIRTGKGRTDVMEVNPYNSVVGLGHSGGTVTMWKPTSQAPLVQMQCHPGPVSSVAFHPNGHLMATSGKERKIKIWDLRKFEEVQTI-HSFHAKTLSFSQKGLLAAGTGSF--VQILGDSSGGMNHSMVKGYQIEKVMFRPYEDVIGIGHSMGWSSILIPGSGEPNFDSWVANPFETSKQRREKHSLLDKLPPETIMLDPSK. 453
26 -64.300[A] KOG0265 U5 snRNP-specific protein-like factor and related proteins  ali follow..  15  6.............................................................................................................................................................................................................................................................................................................................................................................................................................................PNNSVILAQEAKRSKNDLMAYTNRDKALLESGVRRTSNLQ-----APIMQLEGHEGEIFTAEFHPEGELLLSSGDRQIYIWQVYEDCE----NVMAMSGHSGAVMEAHFTPDGSHIFTCSTDKTLAFWDIA--TGQRQRRFKGHGNFVNSVQGSRRGQLLCSGSDDRTIKIWDARKKHAAHTLESP-FQVTAVCFGDTGEQVISGGIDNEVKIWDIRKQAVLHHLGHSDTITGMSLSPEGDFILTNAMDNTLRVWDVRPYAVKVFQGHEKNLLRCAWSPGSDKITSGSADRHVYIWDVNTRRILKLPGHNGSVNAVDFSPKEPLILSGSSDKTLYLGEI.. 345
27 -63.500[A] KOG0272 U4/U6 small nuclear ribonucleoprotein Prp4 (contains WD40 repeats)  ali follow..  15  2....................................................................................................................................................................................................................................................SDDDDIQYIKRQRTLHYGSLEESERKR---QNAAASGAAATTTSGTTASSGAGTTTTGTGGQLEDIDSDEDYEESTKKTSNAKQAGAPPPTAATLANKIDDDYFDLEMEMERD-KVALLEEFERKKRARQINVSTDDTEIKSNLRQLNERLKELLAGLGENAINKRQYEDEERKQQQREQDQATWYHARLWLADYSLPRAKDRLVRAREALEVPSAARAGRMVEKKLQSLAPLCSQVGDTRPVSSAAFSEDSSLLLTSSSGLCKLWSVPDCELKQ-----TLRGHASYVGGVALRPGVKAMASGGHDGAVKLWGFN--NEESIADITGHPHRVSKVAFHPSGRFLATACYDSSWRLWDLEQKTEVLHQEGHAKPVHCLSYHSDGSVLVTGGLDAFGRVWDLRTGRCIMFLGHLGAVFGVDFSPNGFHIATGSQDNTCKIWDLRRRQVYTIPAHTNLISDVKYQQEGSFLVTCSYDSTTKIWSNKTWQPLTLQGHDNKVISVDIAPNSQYIATTSFDRTFKLWSP.. 551
28 -63.100[BK] KOG1063 RNA polymerase II elongator complex, subunit ELP2, WD repeat superfamily  ali follow..  10  4.....................................................................................................................................................................................................................................................................NTKVEAKRVFIGAGCNRVVNNVSWGASGLVSFGAQNAVAVFCPKTA-QILTTLPGHKASVNCTHWLPTSKYLLSGDSDGIIILWELSTLNNDQQWKKGVTCITAYMVSETDAMFASASSDGVVNVWDVSFPSCLDSICVDTKAIVTLSLNPGRFALALGGLDNKIKLYSGERTVCELKGHTDWIRSLDFSLPLHMLVSSSQDKVIRIWKLVLVGDVSVLIGHEDWVYSVEWQPPVIILSASMDKTMMIWRPEKKTGVNVVCVGELSHCALGFYGGHWSPNSLSILAHGYGGAFHLWRNVSSSKQMQKVPSGHFAAVTDVTWARTGEYLLSVSQDQTTRVFSAWKNDARPQVHGHDINCVAMVQGKGNHRFVSGAEEKVVRVFEAPLSESHKLYGHGNELFSLCSDHKGNLVASSCKAQSIWLWEVGTWKAVRLQSHSLTVTHLEFSYDDTLLLSVSRDRHFSVFSIQRTDMAKVEAHKRIIWACSWNPFGHQFATSSRDKTVKIWSV.. 725
29 -62.900[T] KOG0279 G protein beta subunit-like protein  ali follow..  16  2............................................................................................................................................................................................................................................................................................................................................................................................................................................AEGLVLKGTMCAHTDMVTAIATPVDNDVIVTSSRDKSIILWKLTKGVAQRRMTGHSHFVQDVVLSSDGQFALSGSDGELRLWDLATGESTR-----RFVGHTKDVLSVAFSTDNRQIVSASRDRTIKLWNTLGECKYTISEADGHKEWVSCVRFSPNTLVIVSASWDKTVKVWNLQNCKLRNTLAGHSGYLNTVAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLEAGSIIHSLCFSPNRYWLCAAT-ENSIRIWDLESKSV--VEDLKVDLKAEAEKTDGSTGIG-------------------NKTKVIYCTSLNWSADGNTLFSGYTDGVIRVWGIG. 324
30 -62.800[R] KOG2394 WD40 protein DMR-N9  ali follow..  12  3...............................................................................................................................................................................................................................................................NTSNGMISAPSSSSSPAANPQSPGIKTYFKTPEGKYKLHYEKTHSSGHGKTVTQVTIAQLKERAAPSTPTGTSSGYSASSGFRSATARLLGTGNGSRALSFVGGNGGGKSVSTSSRISGSF--------------------AASNSNTSMTNTNFDGKGTYLVFNVSDACDLNSQEKDPVKSIHFSNSNPMCHAFAKDGHDLLIGLNSGDVYTVSLRQQLQDVSVNNRQDRCTSISWVPGGDFVVAHADGNLYNKDGATEKYSKSNPVARWHICQGSINSIAFSNDGAHLATVGRDGYLRIFDFL--TQKLVCGGKSYYGALLCCSWSMDGKYILTGGEDDLVQVWSMEDRKVVAWGEGHNSWVSGVAFDSNWSRFGSVGQDTQLLLWDLEMDEIVVPLRAPGGSPTYSTGSSAHWDNVGTLQPAPCKRDVPKLSIIAHRVHTEPLSGLMFTQES--VVTACREGHIKIWTRPSESETSEANPTTALLSTSFTKDNKASLSSKIISGSTFKQ... 556
31 -61.800[T] KOG4378 Nuclear protein COP1  ali follow..  15  1......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MMSNLVEPSWRLLAASGGDTVKLFDVSADSGDPCVLS-YTPSPGCAVNSVKWNHTNLVVASTGEDKKISLWRKNGQS-TGKDGGDSAEECLSAISFSKKGRYICSGGTGQIVKIWDLQRKLCIKKLKGHTSTITGVMYNCKDEHLASVSVGGDLIVHNLASGARATELQFVHVLRLLDYSRSSRLLVTAGDDGTVHLWDTTGRSPKMLKQHSAPTAGVCFSPSNEIIASVGMDKKLYTYDSGSRRSSSCIAYEAPFSSLAFGDNGYILVAGTSNGRVVFYDI.. 299
32 -61.200[A] KOG0284 Polyadenylation factor I complex, subunit PFS2  ali follow..  13  2.....................................................................................................................................................................................................................................................................................................................NGGMMRGNQMPNVTLTIQPSTSSMQNSQPRIMNNHHHPHNRFQ------REHVMPDVMGDGPGRRLRKNVANVRRHVDYVSTVCENRLWQYGKQRILQQPDILYQQYAVPADSTPDVDCILTKFIRTAMNKVKCPVYSVCWSPEGKRLITGCQTGEFTLWNGTAFNFETILQAHDSAIRALKWASNEQWLLSADGGYVKYWQPNMNNAHM-----FSAHKDEAIRGLAFAPTDVKFATASDDGTARVWDFA--RYTEERVLRGHGAEVRCIDWHPTKGLIATGSRDTPVKIWDPKSGSCLATLQEHKSSVMAVEFNKNGNWLLTGGRDHLVKMYDIRMMKEMRTYAHKKEVISLAWHPIHELFVSGGGDGSIVYWMVDGEKEIGEHAHDQAIWSMKWHPLGHILATGSNDNNTKFWARNRPSNTNMIGHLDKEREPRMAPPKPSIETQETYRPDTFIPGM. 470
33 -61.100[R] KOG2096 WD40 repeat protein  ali follow..  13  2......................................................................................................................................................................................................................................................................................................................................................................................................................DSVLVVGIASVILGALIAVLGSYFRKRTSEVQSMAKAEPQDPIRNPKSNHPAPKKNHPKSQASDKNQNKRLNTLKGHGDAVTGLCFSSDGKSLATACDGVIRVFKLDDASSKSFRFLRINLPAGGHPTAVAFADDASSIVVGKLPLPSIKWDHH--HIHEKRSVLTISGATATYGTADGSVVIASCSEGTDIVLWHGKTGRNLGHVDTNQLKNHMAAVSPNGRFLAAAAFTADVKVWEIVYQKDMQLKGHKSAVTWLCFSPNSEQIITASKDGSIRVWNINVRPLCDSGGNPLHYDRLSLCPEGKILAASH-GSTLQWLCAETGNVLAEKAHEGDITCISWAPKAMVLGTSGDDKKVKLWEAP. 449
34 -60.600[R] KOG0289 mRNA splicing factor  ali follow..  14  2......................................................................................................................................................................................................................................................SLICSISNEVPEHPCVSPVSN--------------------EKYIAENGTDPINNQPLSEEQLIDIKVAHPIRPKPPSATSIPAILKALQDEWDAVMLHSFTLRQQLQT--------TRQELSHALYQHDAACRVIARLTKETAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGTPEIIQKLQDKATVLTTERKKRGKTVP----EELVKPEELSKASHVGLHSASIPGILALDLCPDTNKILTGGDKNVVVFDKSSEQILA-----TLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVP--NASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLDNNFEVKSLIFDQSGTYLALGGTD--VQIYICKQWTEIHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL.. 504
35 -60.300[S] KOG0293 WD40 repeat-containing protein  ali follow..  13  184...........................................................................................................................................................................................................................................................................................................................................................................................................SSFISHTTSTPGKESVNSRSKVLEELQPASVIIPEKRLECLVENSLHIQRDSCVFHNTLDSDLSLYSDHQCGKHQIP-SQTAQILESHTDEVWFLQFSHNGKYLASSSDQTAIIWEISADGHIS--LKHTLVGHHKPVIAILWSPDDRQVLTCGAEEVIRRWDVD--SGDCVHMYEKGGISPISCGWYPDGQGIIAGMTDRSICMWDLDGREKECWKGQRTQKVSDIAMTDDGKWLVSVCKDSVISLFDREATVER-LIEEEDMITSFSLSNDNKYILVNLLNQEIRLWNIEGDPKSRYKGHKRSIRSCFGGYKQAFIASGSEDSQVYIWHRSTGKLIELPGHAGAVNCVSWSPTNLMLASASDDGTIRIWGL.. 561
36 -59.700[S] KOG0316 Conserved WD40 repeat-containing protein  ali follow..  15  7..............................................................................................................................................................................................................................................................................................................................................................................................................................................PTKEAHILKGHEGAVLAARFNGDGNYALTCGKDRTIRLWNPHRGILIKTYKSHGREVRDVHVTSDNAKFCSCGDRQVYYWDVSTGRVIR-----KFRGHDGEVNAVKFNDSSSVVVSAGFDRSLRVWDCR--SHSVEPVQIIDTFLDTVMSVVLTKTEIIGGSVDGTVRTFDMRIGREMSDNLGQP--VNCISISNDGNCVLAGCLDSTLRLLDRTTGELLQVYKSKSFKTDCCLTNSDAHVIGGSEDGLVFFWDLVDAKVLSKFRAHDLVNSIDVDFYLRKFFVAGDKRELPPEGRLYVDFFGRWSCLEKMKKQQILTSIDFVIYVSNSPFFFYYRL.. 343
37 -59.400[J] KOG0650 WD40 repeat nucleolar protein Bop1, involved in ribosome biogenesis  ali follow..  1..........................................................................MTKKLALKRRGKD---------SEPTNEVVASSEASENEEEEEDLLQAVKDPGEDSTDDEGIDQEYHSDSSEELQFESDEEGNYLGRKQSSSAEEDEESSDEEDNEEEESTDGEEVEDEEKDSKSKQTDDKPSGSGAASKKALTAELPKRDSSKPEYQDSDTSDEEDIRNDAKKIIKPPQGDQIDEFLRKIEDPDFWRTVKDPLTGQDVRLTDEDIPNKDHEEYEPWIEWFTSEVEKMPIKNVPDHKRSFLPSVSEKKRVSRMVHALKMGWMKTTEEVEREKQAKRGPKFYMLWETDTSREHMRRIHDPVSAPKRSYNPPPEYLFDAKETKEWLKLKDEPHKRKLHFMPQKFKSLRVPAYSRYLRERFLRCLDLYLCPRAKRVKLNIDAEYLIPKLPSPTVESMVYRGHTDLVRSVSVEPKGEYLVSGSDKTVKIWEIATGR------CIRTIETDEVVRCVAWCPNPKLIIAVATGNRLLLVNPKVGQEKGVRVVITHFKPIRQVTWHGRGDYLATVMPEGANRIHQLSKRRSQIPFSKSKGLIQFVLFHPVKPCFFVAT-QHNIRIYDLVKQELVKKLTNSKWISGMSIHPKGDNLLVSTYDKKMLWFDLDLSTKQTMRLHRNAVRSVAFHLRYPLFASGSDDQAVIVSHGMVYNDLKLQTHEFGVLDVNWHPVQPWVFSTGADSTIRLYT... 784
38 -58.900[A] KOG0268 Sof1-like rRNA processing protein (contains WD40 repeats)  ali follow..  14  3....................................................................................................................................................................................................................................................................................................................................................................................................................VKMLSRNPDNYVRETK--------------------LDLQRVPRNYDPALHPFEVPREYNATKLERVFAKPFLASLDGHRDGVNCLAKHPEKLATVLSGDGEVRIWNLTQRNCIR-----TIQAHEGFVRGICTRFCGTSFFTVGDDKTVKQWKMDGPGGDEEEPLHTILGKTVYTGIDHHWKEAVFATCGQQVDIWDEQRTNPICSMTWGFDSISSVKFNPIETLLGSCASDRNIVLYDMRQATPLKKVILDMRTNTICWNPMEAFFTAANEDYNLYTFDMRALDTMVHMDHVSAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSVYHTKRMQHVICVKWTSDSKYIMCGSDEMNIRLWKA.. 354
39 -58.700[S] KOG0310 Conserved WD40 repeat-containing protein  ali follow..  20  2..............................................................................................................................................................................................................................................................................................................................................................................................................................................................AQPYLPAEKFLSR-------------KQETILLDEDEPAVVSSVRISPKKPYHVATTSVRLTLYDTVVCEPLN-----LFSRFKKGVCSIDFRHDGRLLAIGGDEGKVRIFDVEKSSKVALRVMQASQSTVKSVHFSPRGDTVFSMADDGKIKQYRVADAVPIIEIQAHEDAIRCGAVSSNDHIVLTGGYDHKVRLWDIRSKEKSLELDCEHPVESVLFLPGEQLIATAA-GPIVKIWDTTTGRQLALQAHYKTVTSLRLATNSTCLLSAGIDRRVNAFRTTNYSLINSWSMPSPVLDIDVSRDDQTMAIGMGNLLALYRRA.. 316
40 -58.600[S] KOG0321 WD40 repeat-containing protein L2DTL  ali follow..  14  5..................................................................................................................................................................................................................................................................................................IGKALSDVGGLRDITSRANNSLPPTPDSSPAAPSKKHKLYDFLESRGKIETPRKRIVFEKKPLL--------------------------HKPVHIQKKPAQLCKELLIRQLGGSRSHPFSTKTSRHVGGRLNLETY---YSRPSECLMMLNQLPFCLGFANNESLLAVCTETGALELFDSPSARRIHGWLAHNNAIFSVNFSKDDSLLATSSDQTSKVFDLSTQQCITRLGRRVDGYHSHSVKQVNFCNDSPNLVSCSRDGSIIFWDMRTHG-RKAHENSGRDCSITSATWLPQSTVISSCSANSALKLWDLRTVHTVRPLSKRDFGVTNVCTSPDGERIYAASRDSIIYEYSSRHLNS-PRLRISSFYVKLACSPDGATLACGGKTSGVVVFDTTRNCAMLTGGHTKDVTAVDWSSEGQ-LASISDDGSVRVWNSSLHGSALREKNFSEIFYWGFSEK.................... 490
41 -58.600[JT] KOG0643 Translation initiation factor 3, subunit i (eIF-3i)/TGF-beta receptor-interacting protein (TRIP-1)  ali follow..  12  4...................................................................................................................................................................................................................................................................................................................................................................................................................................................ILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSDNSCRLWDCETGKQLALL------KTNSAVRTCGFDFGGNIIMFSTDKQMVSFFDLRDDNNEPYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTS---------------------------TRIGKFEARFFHLAFEEEFRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYF.. 314
42 -58.600[R] KOG2055 WD40 repeat protein  ali follow..  2.........................................................................................................................................................................................................................EKDTEELELENAVFGNINNFSSFLDKENETFDVMMNEAPELSEDNDAQEDELEKLEDAELFMFDTGSADGAKDSVAGDNTVKEDEEASNEIPSIWEDSDDERLMISLQDHSRLRKLRQYEDEDMVNGLQYARRLRTQFER----------VYPVPEWAKKQDVTEEEDEFNALSEKSVIPKSLKSLFKSSVSYINQSSKLLAPGTINIKRLKDAN----FQAPSHSGIRCMSIHPYFPLLLTCGFDRTLRIYQLDVNPLVTSLHLRSSALQTALFHPDGKRVIAAGRKYMYIWDLESAQVQKVSRMYGQENFQPSMERFHVDPTGKYIALEGRSGHINLLHALTGQ---FATSFKIEGVLSDVLFTSDGSEMLVLSYGAEVWHFNVEQRSVVRRWQVQDGSTTHFCLDPSNKYLAIGSKSGIVNIYDLQTSNADAADNITFSINSMSFSQDSQVLAIASKKDTLRLVHVPSFSVFTSATPLGRVTCLAFGKGGE-LCVGNEAGRVGLWKLAHYDLKFVP-DKIINWEIRLGKFGYVLLGIQVDVVI....... 555
43 -58.400[S] KOG1409 Uncharacterized conserved protein, contains WD40 repeats and FYVE domains  ali follow..  3.............................................................................................................................................................................................................................................................................................................................................................................................................................AIINQRVEQGESSMGGAKPALLHRITGHVARINDVILLSKDEGVWTASDDRSVRLYLKRDNDQFWPSIFMPVAPTSLYYSEETYKLLVGLNGNVYEFSVAD-DFNSMTESRKWTCHAGPISGLGFALSSELIFSCSRDKSIVWHCSENSN-----KMGSYLLENSCTAMVIDLPFVFVGDHGGHVTVLRIVDNQLVSKLSAHTNAITSLTWDGNKKVLYSGSSDHLIIMWDIGGGRGEELNGHNGKVTTLCAAPAAKRLFSADEHGKLMCWDMNCKRVETPERTCGSAVCGSCCDNWTTYPPMGYETKIRICNDCNARLAIPHEIHTGITAMHLQETLGLLVTSGQNRVIMIWDV.. 404
44 -57.800[R] KOG0645 WD40 repeat protein  ali follow..  16  1................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SGHTGRLWSVAAHPMLPLFATSSDKSVRIYNSNTYNLVHVIDG----FHTRSIRRVAWRPIERVLAVASFDSVVSINEKIDDDWECTAALEGHENEVKCIAWSCNGNYLATCSRDKSVWIWEATEDDCLAVLQEHTQDVKVVTWHPTEDLLVSGSYDNSICFWRDDGDDTCQLQGHTNTVWALAFSPNGNTLASADNDGNVFLWIKISSNTSLPHIHKGAVYTISWMNDAT-LCSAGGDGKIVVYQREKHDEALHAHGVYEINSLEYLRDDR-LLSGGDDGECRVWSF.. 321
45 -57.000[R] KOG1524 WD40 repeat-containing protein CHE-2  ali follow..  11  8.......................................................................................................................................................................................................................................................................................................................SRKTRHTEMVCGVGWIGTEA-ILSAADDHVFLLTNTATNESQQILNMPETFFPSQTKGGQNDVFAVSTSDGKINILS-RNGKVENMVDAHNGAALCARWNSDGTGLLSSGEDGFVKMWSSGMLRSVLAQFATAVYCVAWDSTSSNVLYCNADHCYIKS-LKMQVAPIKWKAHDGIILCCDWNPTSDLIVTGGDLKFKVWDGFGQ------ILFNSSVHDYPITSISWNTDGTLFAVGSHN-ILRLCD---KSGWSHSLEKMNAGSVMALSWSPDGTQLAVGTAAGLVFHAHIIDKRLTNTPTMIEYNERTVNIIVQCEKIFLVSDGMTITIFTYEGRKLINQVMALLDERKIDLANDTLVVRDRADNKVLHFFDPTTGKAQGNLKHEHDIVELTVNQCGRNVAFRDQIGAVHIAMVKTFGVSRMVKIGSLVEQLVFNDVTNMLCGIS-EGKIAVWPL.. 532
46 -56.700[R] KOG0646 WD40 repeat protein  ali follow..  16  2....................................................................................................................................................................................................................................................................................................................................................................................................................................................................EITVIASSSIDEGIGSWDLKTGTEQLQFKPCASPAHGLTAVGEKQLSARNTSGSIFYWSWTKPQ------AEVKSYPVEPIKALAANNEGTYLVGGGISGDIYLWEVA--TGKLLKKWHGHYRSVTCLVFSGDDSLLVSGSQDGSIRVWSLIRTLYEHNFNEHTMSVTDIVIDYGGCVIISSSEDRTCKVWSLSRGKLLKNIIFPSVINALALDPGGCVFYAGARDSKIYIGAINATSEYSVSEKGKAITCLAYCADGNLLISGSEDGVVCVWDPKSLRHVTLIHAKGSRKGPVNNQIVRKTIVANSNKTQVSWKS.. 335
47 -56.600[R] KOG1334 WD40 repeat protein  ali follow..  3.....................................................................GLKAAI--ADDLIVMV------------------VASLILATQNPDSVQPFGYCSGAKKLSDVRILWRTIGASEVKLFPYRDKNDHQHLPEGVSNKDFQSGATRKLLLPGVPDQLQQTSFEMSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFLNDASTENQNTDSESSSEDVELESMGEGLFGYPLPRMCPRCGGTNHDQCLLDEDQALEEWISSE---------------------------------------TSALPRSRWQVLTALRQRQLGSSARFVYEACGARTFVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLSGHDINVIQAKFFPNDSTLAMCGHDGQVRVAELINASNTKRVAKHRGPAHELALEPDSPYKFSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANYQFAVGGHDQFVRIYDQRRIDTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQYVKRYKG-KCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMDRGDIVNCLEPHPYLPVLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNLNYTDSFDNRMLRFFVR-HLLQRAHQPGWRDHGAEFPDEEELDESSSTSDTSEEE... 671
48 -56.300[A] KOG0299 U3 snoRNP-associated protein (contains WD40 repeats)  ali follow..  16  90........................................................................................................................................................................................................................................................................................................................................................................................................................................................GGFDAKEVDRELLASRLKEDVLEKTSKINPDVKIETAQLRGRHMRPLVGVVAYENF--VYSADSGLIQKWEALQEKDKFSRSRRGENDHVKEITCLAISNDGRWIVTGGLDHRIVIRDSV--TLEPQHCWKHHRDAVMGLAMRRGTNEMFSCSADRSIKVWSLDQMSYIETLFGHQDVIFGVDALARERCVSVGGRDRTSRLWKIVEESQLATAGYMEGSVDCVAMIDEDHFVTGSDNGVIALWSVQRKKPVTIPPQPRWITSLAAIPYSNLFASGSWDGNIRLWKIAEGLRATPLSVYGCINSLSLSLQGKVFAACGRETRVGRWKTL. 496
49 -55.900[S] KOG1407 WD40 repeat protein  ali follow..  13  2.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................EETTIPFKSLHSR----EYQGHKKKVHSVAWNSNGTKLASGSDQTARIWNIEPHGH-SKAKDLELKGHTDSVDQLCWDPKHSLVATASGDKSVRLWDARSGK---CTQQVELSGENINITYKPDGTHVAVGNRDDELTILDVRKFKPLHRR-KFNYEVNEIAWNMPGDFFFLTTGLGTVEVLSYPSLKPLDTLAHTAGCYCIAIDPKGRYFAVGSADSLVSLWDISDMLLRTFTKLEWPVRTISFNYSGEYIASASEDLFIDIANVQTGRTVHQIPCRAAMNSVEWNPKYNLLAYAGDDKNPKYNT... 302
50 -55.700[DO] KOG0305 Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits  ali follow..  13  30............................................................................................................................................................................................................................................................................................................................................................PNRSAKDFDFANYALTQGSKRNLDEVTSASRKAYMTQLAVVMNQNRTRILAFRNKPKSLLSTNHSDSPHQNPKPVKPRRYIPQNSERAPGLRDDFSLNLLDWGSANVLAIAL--GDTVYLWDASSGSELVTIDEDKGPVTSINWTQDGLDLAVGDNSEVQLWDCVSNRQVRTLR------GGHESRVGSLAWDNHILTTGGMDGKIVNNDVRIRS-SIVETYLGHTEEVCGLKWSESGNKQASGGNDNVVHIWDRSLASSLHRFEEHTAAVRALAWCPFQASLLATGGDGKIKFWNTHTGACLNSVETGSQVCSLLWSQSERELLSGFTQNQLTLWKYPSMSMAELNGHTSRVLFMAQSPNGCTVASAAGDENLRLWNVFGEPPKTTKKAASKKYPELFSHVNSL................. 443
51 -55.300[R] KOG4227 WD40 repeat protein  ali follow..  14  2................................................................................................................................................................................................................................................................................................................................................................................................................................................KRRAGLGGSMRSVVGFLSQRGLHGDPLLTQDFQRRRLRGCRNLYKKDLLGHFGCVNAIEFSNNGQWLVSGGDRRVLLWHMEQAIHSRVKPIQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVILHDVESSE---TLDVFAHEDAVYGLSVSPVNNIFASSSDDGRVLIWDIRESPEPFCLANYPSAFHSVMFNPEPRLLATANSKEGVGLWDIRKPQSSLLRLSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHSRLDNQGYFNSCTMKSCCFAGDRQYILSGSDDFNLYMWRIPADPEAVLKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWS... 361
52 -55.000[Z] KOG0313 Microtubule binding protein YTM1 (contains WD40 repeats)  ali follow..  15  52..............................................................................................................................................................................................................................................................................................................................................................................................................................................................EFDFLIKGQFLRMPLDK-EIEYVEKCTAPQPEQCMFHDDWISSIKGAEEWILTGS-YDKTSRIWSLEGK------SIMTIVGHTDVVKDVAWVKKDSLLLSASMDQTILLWEWNVERNKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEIVTLSGHMEAVSSVLWSDAEE-ICSASWDHTIRVWDVGSGSLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDSLSLTSHTGWVTSVKWSPTHQQLISGSLDNIVKLWDTRSCKAPLLAAHEDKVLSVDWTDTGL-LLSGGADNKLYSYRYS. 415
53 -54.800[S] KOG4328 WD40 protein  ali follow..  12  8.......................................................................................................................................................................................................................................................................................KRLENIRRNDEMLAALNVRAKASSLLSAAKRSRDDSKSFKKKKPKPASTPTVIRMSLRTRGLNPDSAGLPDGFSDFRMGSQITHNQPSPQKQSPRLLAPIPFESAYEGYGSYTQLVDTLLGIESKSCRGKLVKGEIGVVKDENESPMVRTRSSSSKVSVKKEEPEDDSFSDYVNKEFSIPVKPEKIEFDLDLLTLEPQNVARVVPGRIFVVQFLPNVKMVAAGDLGNVGFWNLDCGNEEDNDGIYLFTPHSAPVSSIVFQQNSSRVISSSYDGLIRLMDVEKS---VFDLVYSTDEAIFSLSQRPNDQSLYFGQDYGVFNVWDLRAGKSVFHWELHERRINSIDFNPQNPVMATSSTDGTACLWDLRSMGALSTVNHSRAVHSAYFSPSGLSLATTSLDNYIGVLSGANFENTCMIYHNNSKFKAVWGWDDSYIYVGNLSKKIDVINPKLKRTVMELLQRAIPCRIHCHPNVGTLAGSTAGGQVYVWTT.. 515
54 -54.700[S] KOG0281 Beta-TrCP (transducin repeats containing)/Slimb proteins  ali follow..  14  148...................................................................................................................................................................................................................................................................................................................................................................................................SESRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRNLQRIQCRSENSKGVCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSDSTVRVWDVNTGEVLN-----TLIHHNEAVLHLRFSNGL--MVTCSKDRSIAVWDMASATDTLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQY--RDRLVVSGSSDNTIRLWDIECGACLRVLGHEELVRCIRF--DNKRIVSGAYDGKIKVWDLQAALLRTLVEHSGRVFRLQF--DEFQIISSSHDDTILIWDFLNVPPSQNETRSPSRTYTYIS...................... 507
55 -54.400[R] KOG1273 WD40 repeat protein  ali follow..  11  15.................................................................................................................................................................................................................................................................................................................................................................................................................................................EVIEEYLEHGVIKCVAFNHRGSLLAAGCADGGCVIWDFETRGIAKEIRDNSAAITSVSWSKYGHRLLVSADKSLTLWDVSTGEKIARTILCLACPLSSAPMIVDFDIDCTTLLPVSVPEMPDVLAP---PQRSKCPESNPPFSPAAACFNKCGDLVYIGNSKGEILIVDYKSVRVLALVSSGAAPVKNIVFSRNGQYLLTNSHDRTIRIYENLLPAKNKMKTTKMHWKAPCFSGDGEWVVGGSGEHKIYIWDRAGHLVKILEGPKEALIDLAWHPVHPIIVSVSLAGLVYIWAKDYTESAFAPDFKELEENEEYVEREDEFDLIPETEKVKVLDV.. 389
56 -54.400[I] KOG0301 Phospholipase A2-activating protein (contains WD40 repeats)  ali follow..  13  1.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................MADDGLGDVPMETESMPQYTISHVIEAHKSDTKALAVTQGGCLISGGRDETVKFWAKKGKQYTKTHAFEQ--PKGITVNSIAYAEDGWRLFVGRRDGTIAVFGPS--QAEPYAIFNEHKQNVCCLHINEKATHMLSGSWDSNVIIWPITESFTTIVCPGHTLSVWALASFPDLNTYLSASADKTIRMWFGDTTLSVFK-GHTDVVRALVVLSSSH-FLSAGNDGHIIHWDVASASILRKFATQAHEFIYSMTLSDSHILTTGEDGTLEFWAIDGGKEAVIQLPTTNTWDAKVLLNSD-IAVAGSDGRIYIMTT.. 321
57 -54.200[U] KOG0771 Prolactin regulatory element-binding protein/Protein transport protein SEC12p  ali follow..  14  2............................................................................................................................................................................................................................................................................................................................................................................................................................................ASNQQPPSNLQTYGVPIYAVDWILEEAVRSKITKDQDDDDDDGSSSSSYIVLSGGTDLPYRMAIHPRQGGLICALPNSCRLFDWENINEEESEKVVKELKDVGQQLSLSFNQDGTVLATGAEDGTLRVFEW--PSMKTLLNESKTHASVKSLTFSESGKFLVSLG-APLCRVWDVNASAAIASLSKEKDEFASCRFSVDNSVAANTQRGGSIITWDTTSWRRRSSIKRNNSISAFNVSADGKLLAVGTLEGDVLIIDSTKMQTNQKKAHLGLVTALTFSPDSRCLVSVSFDSRARLTVIKQKGEKVYLWVAALLFVLVYVVLYYLMVAMGIIH......... 383
58 -54.100[Z] KOG1523 Actin-related protein Arp2/3 complex, subunit ARPC1/p41-ARC  ali follow..  11  1............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MSLHQFLLEPITCHAWNRDRTQIALSPNHEVHIYKKNGSQ----VKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQKDGVWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFEAENSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEEFGGSGTGGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVVSTLKTEFLPLLSVSFVSENSVVAAGH-DCCPMLFIYDDRGCLLETLHQNSITQVSIKQDCRKFCTTGIDGAMTIWDF.. 357
59 -54.000[R] KOG4497 Uncharacterized conserved protein WDR8, contains WD repeats  ali follow..  12  1..........................................................................................................................................................................................................................................................................................................................................................................................................MNFSEVFKLSSLLCKFSPDGKYLASCVQYRLVVRDVNTLQILQLYTCLDQIQHIEWSADSLFILCAMKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTHLRITVWSLCTKS------VSYIKYPKACLQGITFTRDGRYMALAERRDCVSIFVCS--DWQLLRHFDTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSDGRLLSTYSEWSLGIKSVAWSPSSQFLAVGSYDGKVRILNHVTWKMITEFGHPAAINDLAFSPDSYFLATRNDNNAVWVWDIQKLRLFAVLEQLSPVRAFQWDPQQPRLAICTGGSRLYLWSPAGCMSVVPGEGDFAVLSLCWHLSGDSMALLSKDHFCLCFLET. 445
60 -53.900[DK] KOG0973 Histone transcription regulator HIRA, WD repeat superfamily  ali follow..  15  2..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TFVGHTGSILAIDCHPSGKKFITCGNGLVVVWNAKKASNENVPKLLFQVESQSQSNSCRWSPDGKRFAFGSDDSSVSVWEYVGLINKECCVLRGHSMEVLTVEWSPNGKYLASGSIDYRIIIYNARKPDRITVLNDIQLPVKGLSWDPIGKYLASLEGDKKLRFWATDSWQCVKSVTEETMLTRLDWSPDGKYLMTPAAVRSIKLIQRQTKSDQFLAGHHKGTTCVRAMPQLTCAAVGSRDKSISIWVFPGTLKLFVINNIFNHTVMDFAWCGRNLLACSQDGTVKVIHL.. 346
61 -53.800[ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA cleavage factor II complex, subunit SWD2  ali follow..  10  2................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KIKLIDVRSFKVAKIFRENTDKINAIDFAPNGEHLISCSDDQIVIYDCEKGTQSR-----TVNSKKYGVDLIHFTHANNTASSTKVDDTIRYLSLH--DNKYLRYFPGHTKKVISLCISPVEDTFLSGSLDKTLRLWDLRSPNCQGLM--HLSGRPIAAYDPEGLIFAAGVNSESIKLYDLRSFDKGPFVEKECDWTGLKFSRDGKTILISTNGSVIRLVDAFHGTPLQTPNNKGIPIEASFSPDSQFIFSGSTDGRVHIWNADTGNKVSVLDHPGPVQCVQFNPKYMMLASACTNMAFWLPTS.. 313
62 -53.600[R] KOG2919 Guanine nucleotide-binding protein  ali follow..  12  4..........................................................................................................................................................................................................................................................................................................................HNVSFSSTMVTSNGDLSLPKLSVTLSAEEILKLRSGRPKNAVESPHAGVPMETSLAAEEEANGDEEEESVRVVDIEDTELTSNGNEAKPEDQELAIAPVLQYFQGALVELGRRCWTSST------EAQHYTKGCYWSPDGTCLLVPVHLDGMHVIEMPSDLQSEVHVPEGGTVYDCVWYPHMNWLATRQHEPIHMWDAFDGSLRCSYSGYDAVDEVMAAISLAFSHDGEQIYAGY-KRCIKIFDTSRPG--RFCDDYPVKFAISCIAQTTAHPTLTCGNWHGYIQHFDLRCSHPLFTLGGHKGGITQLRYGEFGNLFSGARKCDKILQWDMRNYKQLQRHVDTNQRIQFDLASDSNWLASGDTRGFVNVWDLKKYGDSVLPLHSDCCNGVALNPAMPILATSSGQFHFTDQSAQGDNV--TLNGTETTELPAPADVNQNQKEVLYENAVVMWWC.. 483
63 -52.800[R] KOG2321 WD40 repeat protein  ali follow..  11  2.........................................................................................................................................................................................................................................................................................................................................................................................................SLKVQNPNNVRVYTVSGEGVTQRLPNWISKRKLKALSHRIELLQDFEYPEASNRIKCTRDGKYAMATGVKPHIKVFDFAEMSLKFERHTDAENVQFEILSDDWTKSVHLQDRTVDFHSQGGIHYSTRI--------PKYGRDLKYHYPNCDLYLAAAGDEVYRLNLEQGRKIESAQIDSPTGGVNVIDINPMHQLLAFGTDAGSVEFWDPRDRSRVGILEDNSRSVTALKYRNDGLNVAIGLSDGATLLYDLRSSSPYMSKGYSMPIKSLHWMDDGTARVLSADSKIIKIWEKDTGKPFSSIEPTVELNDVCPIEGTGLILTANEGSPMHAFYIPSLNPAWCSFLDNITEEMEENPDDYKFVTKKELLNLGLDHLV. 402
64 -52.500[BL] KOG1009 Chromatin assembly complex 1 subunit B/CAC2 (contains WD40 repeats)  ali follow..  14  9...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AWHNKEPVYSLDFQHGTARLASAGDTNVRIWKVEKGPDGKAIVEFNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKVNDNKETVVKTLRGHLEDVYDICWATDGNLMASASVDNTAIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYVATLSCDRVLRVYSIQKKRVAFNVSMKSFFRRLSFTPDGSLLLTPAGCVESGENVMNTTYVFSLPCPGKATLAVRCCPYRLVFAVASEDS-VLLYDTQQSFPFGYV-HYHTLSDISWSSDGAFLAISSTDGYCSFVTF.. 375
65 -52.400[R] COG2319 FOG: WD40 repeat  ali follow..  12  96...................................................................................................................................................................................................................................................................................................................................................................................................DTISLGRHSSLSRNLVNKTKNASETYQQLLEYALEVERDDNVFTYAKLQKSDMTQK-CPTMVASEKDNKGKLNEKKNRSPENLLPFRILDAPELRDDFYTSLLSWSPKGD-LAIGLAENIYLWSKELG------PTRVLEESIYDVSSVAYSYNGDILAVGRVDGTLQFWQDNERV---PRISIHHPGDIGVLAWKPETNRLLVGKGNGNIFVYDIIAVLVATITNAHDEQVCGLTWNHDGSQFASGGNDNRVCLFKGSDLRQPLYVQQNAAVKALSFCPWQRSLLAGSHDKHIRFYNCFNGKKIDELYCGAQITSIHWSPKYREFSVTTVQHRFAVYSWPQLECLVSVVPDIRCVHSVLTSQTDSIIIASSNETIKFFDL.. 497
66 -51.700[U] KOG0277 Peroxisomal targeting signal type 2 receptor  ali follow..  15  2.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SAVCGGAARMLRTPGRHGYAAEFSPLPGRLACATCGTLLILDPDEAGLR----LFRSFDWNDGLFDVTWSENNEVLITCSGDGSLQLWDTAKAA-GPLQVYKEHAQEVYSVDWSQTRGLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPIPGCFASASGDQTLRIWDVKAAGVRIVIAHQAEILSCDWCKNENLLVTGAVDCSLRGWDLRNVRQFELLGHTYAIRRVKFSPHASVLASCSYDFTVRFWNFSKPDSLTVEHHTEFTCGLDFSLQSPQVADCSWDETIKIYDP.. 316
67 -51.700[A] KOG0647 mRNA export protein (contains WD40 repeats)  ali follow..  10  3................................................................................................................................................................................................................................................................................................................................................................................................................................................................FFNRSNTTSALGTSTAMANEKDLANDIVINS--PAEDSISDIAFSPQQDFMFSASDGKVRIWDVQNGVPQG----RAQHESSSPVLCTRWSNDGTKVASGGCDNALKLYDIASGQ---TQQIGMHSAPIKVLRFPSNTECIVTGSWDKTIKYWDMRQPQPVSTVMMPER-VYSMDNKQSLLVVATAERHIAIINLANPTTIFKATTPLKWQTRCVACYNEADGYAIGSVEGRCSIRYIDDGMQSNGQSLVYPVNSIAFHPLYGTFVTAGGDGTFNFWDKNQRHRLGYPTLQASIPVCSFNRNGSVFAYALSYDWHQGHM... 339
68 -51.200[S] KOG0294 WD40 repeat-containing protein  ali follow..  13  2...................................................................................................................................................................................................................................................................................................................................................................................................................................................................PPEMEIIEATNEELLLGFKLIKSPTKQTFADSSYARSITSLAVQWPWVASGGDGRIFVYDMRTRKQSQ-----IILSHAGRVNTLKFTPDLSLLLSGSDDGHMIATRVGSWTKEYDWQKAHAGQAVTHVSCHPSSKLALSLGGDQVLNTWNLVNGCVAHKTNTLDFQTGCLSWSKQGDHFTLSG-PLVLEIWGIENAHVMRRIEMPSKPICITWL-DGNECLTGLDNGNIAWISLKDEDPTFILAHEVRVKAIAYL--NEFLATVSIAGQIKVWKIDMEEEIARSFMDCRPTDLGLLDLRQFGNVRPVEQRTKVEE... 332
69 -50.500[S] KOG1333 Uncharacterized conserved protein  ali follow..  10  50...................QQLMQVYDALRDYWSYLERRFSRLEDIYRPTIHKKTSLFRFYLVY--------IQTNRNDKAQEFFAKQATELLPFLPSPDTNPTFATYRQWADTFIVSLHNFLSV-----------------------------------------------------------------------QCMPVPVILNFDAECQRTNQVQEENEVLRQKLFALQAEIHRLKKEEQQPEEEEALVQHKLPPYVSNMDRLGDSELAMVCSQRNASLSQSLRVGFLSSLLPQSKKSPSRLSPAQGPPQPQSSAKKESFGGQGTKGKDPTSGAKDGKSLLSGLATGES--GWSQHRQRRLQDHGKERKELFSTTTSQCAEKKPEASG-----PEAEPCPELHTEPVEPLTRASSAGPEGGGVRPEQIVLGQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLLLGVGTVRLYDTEAKKN---LCEININDNMPRILSLACSPNGASFVCNQVPGRLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHECAMSWRAHYGEVYSVEFSYDENTVYSIGEDGKFIQWNIHKSGLKEYSLPSDATGPFVLSGYSG----------------------YKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYKLGGDEKCLSLGGHRAPVVTVDWSTDCGTCLTASMDGKIKLTTLL. 743
70 -50.100[D] KOG1036 Mitotic spindle checkpoint protein BUB3, WD repeat superfamily  ali follow..  15  1...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MTTVTPSAGRELSNPPSDGISNLRFSNNSDHLLVSSDKRVRLYDVSTNSLKGEF------LHGGAVLDCCFHDDFSGFSVGA-DYKVRRIVFNVGKEDILGT-FSILFFYTLCLFCDVTGQVITGSWDKTVKCWDPRGASGPERTQTYLQPERVYSMSLVGHRLVVATAGRHVNIYDLRNMSQRRESSLKYQTRCVRCYPNGTGYALSSVEGRVAMEFFDLSESEAGRDIVYPVNSIAFHPIYGTFATGGCDGFVNIWDGNNKKRLQYSKYPTSISALSFSRDGQLLAVASSYTAIFVRSVN. 338
71 -50.100[R] KOG2444 WD40 repeat protein  ali follow..  12  4.......................................................................................................................................................................................................................................................................................................................................................................................................................................................EFDNPPLCMKSNKDGSRLVVGFVDGSIRFYDTQQHEEEFQEIQTKSSIRGVDLDEHKKRVYAVTNRSLCVFDIDTGKRVRCIL----KCHRSVPTAICTLPKSQQLATADESGEVKTWNLDPEENANIRKWQEQDEDINDLKVDVKSNLLATSS-DGTLGAYDLRKAKLKMRSELMHSEL--YSVCGTNRSVYVGGEDGYVEVFNLNEYGNLLERGFEMGVNGIVELRSGLLGLTSQGSNRMRLLNVQPSKRLDEKSDDDGIDAITISTDKSTVTMISMSCTIKKWDMGPIIDEIPILRAQDAKSKKMRKTEGFFDGLVGPKNDSDSD... 346
72 -49.900[T] COG5170 Serine/threonine protein phosphatase 2A, regulatory subunit  ali follow..  13  1.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................MDDIEDSLDQWKFAQCFGDKGDVEDITEADIISAVEFDHTGDYLATGDGGRVVLFERNHSKKGCEYKYLKSLEIEEKINKIRWCKRTNHFLLSTNDKTIKLWKLYEKNYPRRVYANAHAYHINSISVNSDAETYISAD-DLRINLWNLSISDHSENMEELTEVITSAEFHPNCNHLMYSSSKGNIKLLDLRQSALCDNPEIISSISDVKFSQNGRYILSR-DYLTLKIWDVNMEKAKTIPLHDVDKFECTFSGDDKHVLSGSYSNNFGIYPTDSSLPGDRGDYNKKILHASWHPFEDSVAIAATNN-LFVFS... 461
73 -49.900[T] KOG1354 Serine/threonine protein phosphatase 2A, regulatory subunit  ali follow..  12  2..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................AGAGGGNDIQWCFSQVGAVDDDVAEADIISTVEFNHSGELLATGDGGRVVIFQQEQENKIQSHSRLKSLEIEEKINKIRWLPQKNQFLLSTNDKTIKLWKISEEASPRRIFANAHTYHINSISINSDYETYLSAD-DLRINLWHLEITDRSANMEELTEVITAAEFHPNSNTFVYSSSKGTIRLCDMRASALCDRHEIISSISDVKFSHSGRYMMTR-DYLSVKIWDLNMENRETYQVHEYDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEDFNKKILHTAWHPKENIIAVATTNN-LYIFQ... 443
74 -49.600[R] KOG0322 G-protein beta subunit-like protein GNB1L, contains WD repeats  ali follow..  13  2.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AVLPPDPVFSLRSPDGAVNSLCFQESDRLLAGTIKGSVFLWDLQTNRSAL-----HFEVGSDPITSLHHTPDR--LVTQEKGGTITMFSIGGSSYVKERSIPGNRSALHTNTSKTNEQLLFYPCEESSIGVLHVTDAAAPTQILVPDDPCFKPFECASQLFLLAGYESGHFLTWDISSSVILDVMELAQDATSVDYDPVTNRGIVGGPTDKLISFSYQRSSGSELCIKNPGVNGVRIRPDQKVFASAGWDGRIRIFSWKSLRPLAVLTKNGGVMDLAFSSQAPIMAAAGMDGQISLWDL.. 321
75 -48.900[U] KOG1332 Vesicle coat complex COPII, subunit SEC13  ali follow..  15  9...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DTSHEDMIHDAQMDYYGTRLATCSDRSVKIFDVRNGGQI---LIADLRGHEGPVWQVAWAHPGNILASCSYDRKVIIWREENGTWEKSHEHAGHDSSVNSVCWAPHGLILACGSSDGAISLLTYTGEEVKKINNAHTIGCNAVSWAPAVKRFASGGCDNLIKLWKEEEDGQWKEEAHSDWVRDVAWAPSTSTIASCSQDGRVFIWTCDDASPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQSDVNKGQGSVSSVTEGQQNEQ................. 322

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zhao Y, Hong DH, Pawlyk B, Yue G, Adamian M, Grynberg M, Godzik A., Li T. The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesis. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3965-70. Epub 2003 Mar 21.