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Query: [J] KOG1145 Mitochondrial translation initiation factor 2 (IF-2; GTPase), from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLNGAALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNTDIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRSPVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKVKKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITGWRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREKYGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDASHECELELVHFGVGDISANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIYRLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFKLTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAKTSWDPGFLast
1 -171.000[J] KOG1145 Mitochondrial translation initiation factor 2 (IF-2; GTPase)  ali  100  1MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLNGAALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNTDIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRSPVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKVKKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITGWRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREKYGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDASHECELELVHFGVGDISANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIYRLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFKLTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAKTSWDPGF 727
2 -124.000[J] COG0532 Translation initiation factor 2 (IF-2; GTPase)  ali follow..  32  271.APATDSFTPATSGKTSRRDRDRKKSDNNRDNTKDGNRKGGPLRVNDNRNQVRNARNSNWNQKGGRGRYQNNQSSSVPATQRKFHELPESLEYEVGMNVQDIAKSIKREPAEIIKKLFMMGT---MVNQNQSLDEDTIELILMDYGVTPVKKVEEDKSDIE-RLFVEDGYLKEENMVERPAVVTIMGHVDHGKTTLLDRFRESRVTEGEAGGITQHIGAYQIKA-NGKKITFLDTPGHEAFTSMRARGASVTDITILVVAADDGVMPQTIEAINHSKAAGVPIIVAINKIDKPGANPQRVTQELTEHGVFPVAWDPGSEFVEISAKFNQNLDELLDTVLLVAEVQELKADPTVRAIGTVVEARLDQGKGAIATLLVQQGTLHVQDPIVVGNTYGRVRTMTNDLGRRIKEAGPSTPIELTGLSDVPQAGDHFAVFEDEKAARAAGEERAKRAQLIKRQNTRRV-------------------------------------NLDNLFDTLKEGQTKSVNIIIKADVQGSAEALAASLQKI-EVEGVKVDIVHSAVGAISESDISLAAASNAIIIGFNVRPTGLAREQAAQEEVDIRLHSIIYKVIEEVETAMRGMLDPEFKEEIIGEAIVRETFNVS---KVGTIAGFMVIRGKVARDASVRVIREGVVIHDGAIASLKHFKDDVKEVGNAQEGGLMVEDFN-DVEIDDTFEVYKMVEIERK....... 944
3 -30.800[E] COG4917 Ethanolamine utilization protein  ali follow..  20  4......................................................................................................................................................................................IAFVGSVGAGKTTLFNALQGNYTLARK----TQAVEFNDK--------GDIDTPGHPRWYHALITTLQDVDMLIYVHGANDP--ESRLPAGLLDIGVSKRQIAVISKTDMPDADVAATRKLL-------LETGFEEPMFELNSHDPQSVQQLVDYLASLTKQEEAGEKTHHS..................................................................................................................................................................................................................................................................................................................................................................................... 158
4 -28.000[M] COG0481 Membrane GTPase LepA  ali follow..  17  7......................................................................................................................................................................................FSIIAHIDHGKSTLSDRLIQTCGGLSDREMEAQVLDSMDLERERG-QLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIEMNLEVVPILNKIDLPAADPERVAEEIEDI---------AMEAVRCSAKTGVGIEDVLEEIV--HKIPAPEGDPNAPLQALIIDSWFDNYLGVVSLVRIKNGTLRKGDKIKVMST-DRLGIFTPKQVDTTILNCGEVGWVVCAIKDILGAGDTLTSHNNPKKVKPQVYAGLFPISSDDYEAFRDALGKLSLNDASLFYEPENSTALGFGFRCGFLGLLHMEIIQERLEREYDDLITTAPTVVYEVEKTDGEVIYVDSPSKLPPLNNCNMLLPQTYLGNVITL-LTYEIPMGEVVLDFFDRLKSTSRQAADMVRVDIMINGERVDALALIVHKDNAPYRGRELVEKMRELIPRQQFDIAIQA---------AIGNHIIARSTVKQLRKNVLAYGGDVSRKKKLKEGKKRMKSLGNVEVPQEAFLAILHVGK.................... 596
5 -27.700[J] KOG0462 Elongation factor-type GTP-binding protein  ali follow..  16  45......................................................................................................................................................................................FGIVAHVDHGKSTLADRLLEMCGAVPPGQGIT--VKAQTAALRRGYLLNLIDTPGHVDFSAEVSRSLAVCDGILLLVAANQGVQAQTIANFWLAFEKNIQIIPVINKIDLPGADIKSVETQLKNL---------PEECLHISAKSGLNVDKVLEAII--DRVPAPTAIIDAPFRSMIFDSYFDHFRGAIAHIMVKEGSVKKGDKIQSYQN-SEVGVMRPEMVKCTELRAGQVGYLVCNMRTVNEAGETLFAETTSRDSVKTFAEIKGVK-FPVETSDYESLKQAVERLCLNDPSVTVIPDSSKALGLGWRIGFLGVLHMEVFGARLSQEYDASVSVEYRAKIKDNETIRKKRYDGMEEIVKVRMIVPNEMMGTVNGL-ILWRLPLAEVAVDFFERLKKLTSGYASFDYEPDGWQDTRLVKLTILINSKESQIIPAAMARDRAKILVQRLKRIPRQQFEVTIKACIGSSTKALSQIVIQPMKRDFSQ-ERLNKKLSHQKKGKERMKMVGNVQIPKEAFLNVLK....................... 644
6 -27.400[J] COG3276 Selenocysteine-specific translation elongation factor  ali follow..  23  2.....................................................................................................................................................................................IIVTSGHVDHGKTALLKALTGTSLPEEKKRGMTIDLGYAYLPLENKV-LGFIDVPGHEKFLSNMLAGLGGVHYAMLIVAADEGVAVQTKEHLAILRQLQFH-IVVITKADRTNSAIESLIQTIKQDYSFLR----NANYFVTSAETGQGISELRHYLANLAE----LADTQKPFRYAIDRVFSVKGAGTVVTGTAFSGTVKVNDEILSTGQKIRIKAI-HAQNTSSEQGIAGLALNLNA-RTPMKRGDWLLQNEPLPPTDRI............................................................................................................................................................................................................................................................................................ 263
7 -26.700[T] COG1217 Predicted membrane GTPase involved in stress response  ali follow..  18  8......................................................................................................................................................................................IAIIAHVDHGKTTLVDKLKLSGTLDRKE-GIT--ILAKNTAIKNGYNINIVDTPGHADFGGEVERVMSMVDSVLLVVDAQDGPMPQTRFVTQKAFKAGLRPIVVVNKIDRPGARPDWVIDQIFD---LFDNLGATDEQLDFPIVYASALNGIAGLDHEKMHVPAPVVDTEGPFQMQISQLDYNSFLGVIGIGRITRGKVKSNTPVVAISD-LKIMGHHGLQRVEVAEAEAGDIVCVSGMEEL-FISDTLCDPQNVEALPPLTVDQPTVSMTFQVNDSPFAGREGKFVTSRNIKERLEKELLHNVALRVEPGDSPEKFKVETMRREGFELAVGRPEVVIIEKDGEKQEPYENVTIDIEEQVRLEYTIPARGLIGFRNNFLTLTSGTGILFSHYGPIKAGEVSNRQNGVLVSMATGTALTYSLETLQSRGKLFLGPIYEGQLAGINSRDNDLVINPTKGKKLDNMRASGKDEVIALVPPIRFTLEQALEEVTPKSIRLRKKMLNENDRKRY.................................... 600
8 -24.000[J] KOG0466 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  15  1............................................................................................................................................MAGGEAGVTLGQPHLSRQDLTTLDVTKLTPLSHEVISRQATIIGTIGHVAHGKSTVVKAIRNITIKLGRPECYRSCGSSMPDEFPLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCQPQTSEHLAAIEIMKLKILILQNKIDLVKERAKEQYEQILA--FVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPP--RDFTSEPRLIVIRSEVDDLKGGVAGGSILKGVLKVGQETEV-SIFSKIVSL-FAEHNDLQYAAPGGLIGV-------TKIDPTLCRADRMVGQILGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKV------QKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPV------CTEVGEKIALSRRVEKHWRLIGWGQIRR......................................................................................................................................................................... 461
9 -23.500[J] KOG0460 Mitochondrial translation elongation factor Tu  ali follow..  23  55.....................................................................................................................................................................................NIGTIGHVDHGKTTLTAAITKDKAPEEKARGITISSAHVEYETANRH-YAHVDCPGHADYIKNMITGAATMDGAIIVVSATDGQMPQTREHLLLARQVGVKIVVYINKVDMVEPD-ELVEMEMRE--LLSEYGFDGDNTPIVSGSALCALEGREPEIKLMEAVDSYITLPERKTDV-IEDVFSISGRGTVVTGRVERGTLKKGAEIEI-HLKTTVTGIMFKKQLDAAVAGDNCGLLLRSIKREQLKRGMIVAQPGTVAPHQKFKASFYILTKEE................................................................................................................................................................................................................................................................................ 358
10 -22.800[J] COG5257 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  25  8.....................................................................................................................................................................................NIGLVGHVDHGKTTLTKALSGVTHSEETKRGISIRLGYADITFRKCRKVSFVDAPGHETLMATMLSGAALMDGAILVIAANEPCQPQTKEHLMALDVIGVKVIVVQNKIDIVSKEALESYREIKE--FVKGTCAEDAPIIPVSAQQGANIDILIETIEERIKTPK--RDVDKPARMYVARSDPEHLAGGVIGGSLVQGRLRVGDEIEI-SLHSTITGL-VAGGEEMEEVGPGGLVGV..................................................................................................................................................................................................................................................................................................................... 292
11 -22.700[J] COG0050 GTPases - translation elongation factors  ali follow..  24  14.....................................................................................................................................................................................NVGTIGHVDHGKTTLTAAITTVNAPEEKARGITINTSHVEYDTPARH-YAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPIIVFMNKCDMVDDE-ELVEMEVRE--LLSAYDFPGDDLPVVRGSALKALEGEAEWEAKIIELAGYERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIVKVGEEVEIDTVKSTCTGVMFRKLLDEGRAGENVGVLLRGIKREDIERGQVLAKPGSIKPHTTFESEVYILSKDE................................................................................................................................................................................................................................................................................ 316
12 -22.000[R] COG5258 GTPase  ali follow..  19  21.................................................................................................DVDRMAGQLKRRLAE--EAVYLIGVSNDLPDEELVKALETLREMARRVGASLYILRVSEGIRGKVAEVLLRAVSREEPPPT---TVVALGNVDAGKSTLVGVLTTGRLDDGKG-GRTSAVSLRLLGFSGDKLVLLVDVGGHERYLRTALRGSSQPDYVMLVVAANSGVQKMTKEHLGIAVAIGIPVFVVVTRIDITPSEVEEVVRILKMPGVSKIPYGRVAPVFYVSSVTGHGLDLLLRFLSLLPRR---RWDYGGEFLMYISDIYLVKGVGVVIGGLVEKGILHVGDRVWLGPY-TVVKSI-HFNRTPVESAKAGSFITV-ALDKVEKVEKGMVLSARPLKAVREVTAD........................................................................................................................................................................................................................................................................................ 435
13 -21.400[J] KOG0465 Mitochondrial elongation factor  ali follow..  15  73......................................................................................................................................................................................IGISAHIDSGKTTFTERVAIHEVRGRDN-GITIQSAATYCS-GKNYHFNLIDTPGHIDFTIEVERALRVLDGAVLVVCAVSGVQSQTVTVDRQMRRYNVPRVTFINKMDRMGSDPFRAIEQLNSK--SESSLSGVVDLINRSALANTGIQPVLDAIV-NEAKVNLVPAVQQPFVGLAFKL-EEGKYGQLTYVRVYQGRLRKGNYITNVKT-ARLVRMHSSEMEDVDEVGSGEICATFGIDCA--SGDTFTDGSVQYSMSSMLSITPNSKDASNFSKALNRFQKEDPTFRVKFDPESKETIISGMGELHLEIYVERMRREYNVDCVTGKPQVSYRESITIGRVIGTLSPVDDITKGNIFETAIVGGRIPDKYLAACGKGFEEV-CEKGPLIGHRVLDVKMLINDGAIHAVDSNELSFKTATMSAFRDAFLRIMEPIMNVSVTSPNEFQGNVIGLLNKLQAVIQDTENGHDEFTLKAEC------------ALSTMFGFATSLRASTQG...................................... 728
14 -21.200[P] COG2895 GTPases - Sulfate adenylate transferase subunit 1  ali follow..  16  30......................................................................................................................................................................................FLTCGSVDDGKSTLIDQLSSLHNDSKRHGGITIDVAYRYFSTEK-RKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKLVVAINKMDLVDYSEETFTRIREDYLTFAGQLP-DIRFVPLSALEGDNVASQSESM-TLLEVLE-RVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVSGVESNVARIVTF-DGDREEAFAGEAITLVLTDEI-SRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREV-------------ENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTV--GAGMVHE......................................................................................................................................................................... 436
15 -21.000[J] COG4108 Peptide chain release factor RF-3  ali follow..  14  18......................................................................................................................................................................................FAIISHPDAGKTTITEKVLLFGRAIQVAGGISVTTSVMQFP--GDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDAAKGVEDRTRKLMEVTRLRDTPIVTFMNKLDREIRDPMELMDEVENE--CGKEFKGVYHIHR-TALGNFGVDHMLDGLT-AERVVEASEEKFTGFVFKIQANMDPKHRDRIAFVRIVSGTYKQGMKMNHVRL-SDAVTFMAGDRARAEEAFAGDIIGLHNHGTI-QIGDTFTQ--------------------------------------------------------------------ETLKFTGIPNFAPELFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVDLIVGAVG-----VLQFDVVVSRLKSEYNVEAIYEGVNVATARWVE....................................................................................................................................... 477
16 -20.900[J] KOG0458 Elongation factor 1 alpha  ali follow..  13  170......................................................................................................................................................................................FVVLGHVDAGKSTLMSQLRKLQRESETMGGVTVSICTSHFSTHR-ANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNAFEQTKEHMLLASSLGIHLIIAMNKMDNVDWSQQRFEEIKSKLLPYLVDIGDNINWVPISGFSGEGV-STLENAAFKISKENEGINKDDPFL--IIPSKKTSNDLALVSGKLESGSIQPGESLTISEQSCIVDKITNHEETDVAIKGDFVTLKLRKAYPEDIQNGDLAASVDYSSIHSAQCFVL-------------------------------------------------ELTTFDMNRPLLPGTPFILFI--VKEQPARIKRLISFIDKGNTASKKKIRHLGS--KQRAFVEIELIEVKRWIPLLTAHENDRLGRVVLRKDGRTIAA-GKISEITQ........................................................................................................................... 611
17 -20.300[J] KOG0468 U5 snRNP-specific protein  ali follow..  15  134......................................................................................................................................................................................VALVGHLHHGKTTFVDCLRYTDTLFTEQ-GCSIKATPVTLVLQDVKLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQERQAITVCINKIDRLILELKKLKHIVEEVNGLLSTYGAPDDNLLVSPILGTTLSDTLAELNVRVSKEEMKSNIRPLLRLVFVDMCVDDCTFFQVLARIVSGTLHAGQEVRV-LQVGRLWVFESRYKVELNRVPAGNWVLIEGIDQCIVKTSTIVDINVPEDLYIFRPLKFNTQSIIKIAVEPVNPSEKMLDGLRKVNKSYPLLSTRVEESGEHVILGTGELYLDCVMHDLRK-MYSEIDIKVADPVVAFCETVVETSSL--GPDSTGPNILVDDTLPSEVDKNLLTAVKDSIVQGFQWGTREGPLCEEPIRNVKFKILDGVIQIIPTARRVAYSLMEPYLFVEVQAPADCVSAVYTVLARRRGHVTQDAPVSGSPIYTIKAFI----------PAIDSFGFETDLRTHTQG...................................... 896
18 -20.100[J] KOG0459 Polypeptide release factor 3  ali follow..  28  104......................................................................................................................................................................................VVFIGHVDAGKSTIGRQIQKYEKEAKDKSGKTVEVGRAHFETES-TRFTILDAPGHKSYVPNMISGASQADIGVLVISARKGEFEQTREHVQLAKTLGVSLIVVVNKMDDPTVNEQKMVPFLKASGYNTKK---DVVFLPISGLMGKNMDQRMGQEISFFEVLDSIEIPPRDPNGPF--IDKFKDMGTVVMGKVESGSIREGDSLVVNKEQVKVVAICDEDKVKRAGPGENLRVRITGIEDE-LSGFVLSSIVNPVPAVTEFVAQ........................................................................................................................................................................................................................................................................................ 425
19 -20.000[J] COG0480 Translation elongation factors (GTPases)  ali follow..  18  13......................................................................................................................................................................................IGIAAHIDAGKTTTTERIKIGEVHEGTA-GITITAAAISTS--KDYQINIIDTPGHVDFTIEVERSMRVLDGVIAVFCSVGGVQPQSETVWRQADRYKVPRIAFINKMDRTGANFYRVHEQMRDR----NDFKGIVDLVRKSAFKNKGVQLMLDAVV-NGDAIERRADDNEPLAALAFKIMADP-YGRLTFVRVYSGVLKKGSYVLNATK-SRLVLMKADDRQDVEELRAGDLGAALGLKDT-LTGDTIVILESLFIPEPVISVAVEPKTKNDMDKLSKALQSLSEEDPTFRVNVDPETNQTVIAGMGELHLEILVDRMLREFK---EANVGAPQVAYRETIRKPVTNVEGKFIRQSGGKVINLEPGEPGTGFEFVSKIVGGVVPKEYI-GMKESCESGILAGYPLIDVKATLVHGSYHDVDSVLKASPVLLEPMMKVEVEVPEDYIGNVIGDLISRRGQIESQSTEQGLAKVASKV------------PLATMFGYATDIRSKTQG...................................... 662
20 -19.600[J] KOG0469 Elongation factor 2  ali follow..  16  22......................................................................................................................................................................................MSVIAHVDHGKSTLTDSVSKAGIIAGSKACITIKSTAISLFFENGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLFMNKMDRALLELQLGAEELVQVDKLMKNLWGDPLMKVFMRKWLPAGDTMLQMIA-EAAVAIKTCDPNGPLMMYISKMVPSDKGRFYAFGRVFSGKVATGMKARI-KTIQRTILMMGRFIEPIEDIPSGNIAGLVGVDQFEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVQSESNQICLSKSPNKHNRLHCTAQPMPDGLADDIEGGTVNARDEFKARAKILAEKYEYDVTEARKIWCFGPDGTGPNLLMDVTKGVQYLNEIK-----DSVVAGFQWATREGVLSDENMRGVRFNVHDVTLHFYASVLTAEPRLLEPVYLVEIQCPEAAVGGIYGVLNRRRGHVFEESQVTGTPMFVVKAYL----------PVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPLEAGTKPNQIVLDTRKRKGL 838
21 -18.000[R] KOG2486 Predicted GTPase  ali follow..  22  136....................................................................................................................................................................................PEFALVGRSNVGKSSLLNSLRKRLALTSKKPGKTQCINHFRI----NDKWYLVDLPGYNKFTKDYFLNRSTLVSVFLLVDASIPVKPIDLEYASWLGQNQVPMTLIFTKCDKRKKKKNGGKKPEANIKEFQDLIQTTPPWIMTSSVTNQGRDEILLHMAQLRN................................................................................................................................................................................................................................................................................................................................................................................................ 313
22 -17.900[J] COG5256 Translation elongation factor EF-1alpha (GTPase)  ali follow..  23  13......................................................................................................................................................................................LITIGHVDHGKSTLVHIIEEYRKEAEQKGGVTIDLAHRKFETDK-YYFTLIDAPGHRDFVKNMITGTSQADAAILVISAREGVMEQTREHAFLARTLGVPMVVAINKMDATSPPYSEKRYNEVKADALLRSIGKDISFVPISGYKGDNVTKLLQAL---DAFKVPEKPINKPLRIPVEDVYSITGIGTVPVGRVETGVLKPGDKVIFADKQGDVKSIMHHEPLQQAEPGDNIGFNVRGIAKN-KRGDVCGHLDTPPTVVKAFTAQ........................................................................................................................................................................................................................................................................................ 326
23 -17.500[J] KOG0052 Translation elongation factor EF-1 alpha/Tu  ali follow..  23  10......................................................................................................................................................................................IVVIGHVDSGKSTTTRTIEKFEKEAQEMGGITIDIALWKFETAK-YYITIIDAPGHRDFIKNMITGTSQADCAVLVVACGTGEFEQTREHALLAQTLGVKLIVACNKMDSTEPP-TEITNEVSGFIKKIGYNPKAVPFVPISGFNGDNMKTLLEAL---DSIIPPQRPTDRPLRLPLQDVYKIGGIGTVPVGRVETGIIKPGMVVTFQNVTTEVKSVMHHESLPEAVPGDNVGFNVKNVSVKDIRRGSVCSDSKQDPAKEARTFHAQ...................................................................................................................................................................................................................................................................................... 343
24 -16.800[R] COG3596 Predicted GTPase  ali follow..  17  2...............................................................................................................................................VMKNFEVLQPLQNSLSGLPLWVSERILQQINQLTHYEPVIGIMGKTGAGKSSLCNALFAGEVSVSDVAACTRDPLRFRLQI-GEHFMTIVDLPGDTEYAALYREQLPRLDLILWLIKADDRALATDEHFYRQGEAYRHKMLFVISQSDKAEPSTEQKQNISRKICLLHELFQPVHPVCAVSVRLQWGLRVMAERMI.................................................................................................................................................................................................................................................................................................................................................................................................... 213
25 -16.300[R] COG0218 Predicted GTPase  ali follow..  17  26....................................................................................................................................................................................PEIALAGRSNVGKSSFINTMRKNLARTSGKPGKTQLLNFFNI----DDKMRFVDVPGYRVSKKEREKWGCMIEAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESAIKKKL---NFDPSDDFILFSSVSKAGMDEAWDAI..................................................................................................................................................................................................................................................................................................................................................................................................... 191
26 -15.600[R] COG2229 Predicted GTPase  ali follow..  18  6......................................................................................................................................................................................IIFTGPVGVGKTTAIAAISDEALVQTDASASTVAMDYGAISLDEDTKVHLYGTPGQERFNFMWEILSQGSMGLVLLL---DNARTNPLKDLEFGLLEKAPVVVGITKMDIRSQGIDVYHKYLAKHNL-------NVPVFEIDARKEDDVKQLVSAMLFSID................................................................................................................................................................................................................................................................................................................................................................................................ 173
27 -14.900[R] COG1159 GTPase  ali follow..  21  7..................................................................................................................................................................................YCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGPYQAIYVDTPGNRLMNKAASSSIGDVELVIFVVEGTRWT-PDDEMVLNKLRDGKAPVILAVNKVDN------QEKVDLLPHLQFLASQMNFLDIVPISAETGMNVDTIAGIVIIREKLMRFLGAELPYSVTVEIERFVTNERGGYGLILVEREGQKK---MVIGNKGAKIKTIGIEARKDMQE.............................................................................................................................................................................................................................................................................................................................. 267
28 -14.400[R] KOG0075 GTP-binding ADP-ribosylation factor-like protein  ali follow..  17  23......................................................................................................................................................................................LTLVGLQFSGKTTFVNVIASGQFAEDMIPTVGFNMRKITR---GNVTIKVWDIGGQPRFRSMWERYCRGVNAIVYMVDAAD-SRNELHSLLDKPQLAGIPVLVLGNKRDLPGADETGLIERMNLSSIQDREI----CCYSISCKEKDNIDITLQWLI.................................................................................................................................................................................................................................................................................................................................................................................................... 178
29 -14.400[U] KOG0076 GTP-binding ADP-ribosylation factor-like protein yARL3  ali follow..  21  20......................................................................................................................................................................................ILILGLDNAGKTTFLETLKKEYSLAKALEKIQPTVGVATIPVDSKQILKFWDVGGQESLRSMWSEYYSLCHGIIFIVDSSD-CSTTLQSVVMDEEIEGVPILMLANKQDRQDREVQDIKEVFNKIAEHISA---DSRVLPISALTGEGVKDAIEWMI.................................................................................................................................................................................................................................................................................................................................................................................................... 183
30 -14.000[R] COG1084 Predicted GTPase  ali follow..  16  130...................................................................................................................................................RISSVIKRIEGDLDFLDFAKNKLRNMPTVDLDAFTVVIAGFPNVGKSTLLRTLTGAEPEVADYPFTTKGIQIGHLER-KWKRIQVIDTPGNNIELQAMVALENIADVIMFIFDASETCGYTLESQYS-RSVFDIPVVTVFNKMDL--AENVKYLEEYINM-----------DPLKVSAFEGRGVSKIIKKLEGLYEKETREAHDN....................................................................................................................................................................................................................................................................................................................................................................................... 335
31 -13.900[U] KOG0090 Signal recognition particle receptor, beta subunit (small G protein superfamily)  ali follow..  20  53.................................................................................................................................................................................TKSNTVLLSGLSGSGKTVLFYQLRDGSSHQGAVTSMEPNEGTFVLHNEKVKPVHLIDVPGHSRLISKLEEYLPRAAAVVFVVDALE--IRAASEYLASVIKNKTPVLLCCNKTDKVTAHTKEFIRKQMEKEID-SHCHNKVTVAEASGLTG-ETDQVQEFI..................................................................................................................................................................................................................................................................................................................................................................................................... 254
32 -13.900[R] KOG0074 GTP-binding ADP-ribosylation factor-like protein ARL3  ali follow..  22  20......................................................................................................................................................................................ILLLGLDNAGKTTLLKQLASEDISH-----ITPTQGFNIKSVQQGFKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSAD-TGQELAELLEEEKLSCVPVLIFANKQDLLTAPASEIAEGLNLHTIRDRVW----QIQSCSALTGEGVQDGMNWVC.................................................................................................................................................................................................................................................................................................................................................................................................... 174
33 -13.700[U] KOG0071 GTP-binding ADP-ribosylation factor Arf6 (dArf3)  ali follow..  21  24......................................................................................................................................................................................ILMLGLDAAGKTTILYKLKLNQSVV-----TIPTVG-FNVETVTYKNIKFNDVGGQDKIRPLWRHYFTGTKGLIFVVDSAD-ARQELHRIISDREMRDCLLLVLANKQDLPGASPAQITDVLQLDKLKDRLW----NVQPTCALTGDGLLEGLAWLS.................................................................................................................................................................................................................................................................................................................................................................................................... 178
34 -13.600[U] KOG0070 GTP-binding ADP-ribosylation factor Arf1  ali follow..  18  20......................................................................................................................................................................................ILMVGLDAAGKTTILYKLKLGEIVT-----TIPTIG-FNVETVEYKNISFTDVGGQDKIRPLWRHYFQNTQGLIFVVDSND-ARDELHRMLNEDELRDAVLLVFANKQDLPNANAAEITDKLGLHSLRQRHW----YIQSTCATSGEGLYEGLDWLS.................................................................................................................................................................................................................................................................................................................................................................................................... 174
35 -13.600[U] KOG0072 GTP-binding ADP-ribosylation factor-like protein ARL1  ali follow..  20  20......................................................................................................................................................................................ILILGLDGAGKTTILYRLQVGEVVT-----TIPTIG-FNVEQVTYKNLKFQDLGGQTSIRPYWRCYYSNTDAIIYVVDSAD-SKDELLYMLREEELAGAILVVLANKQDMDGCTVAEVHHALGLENLKNRTF----QIFKTSATKGEGLDQAMDWLS.................................................................................................................................................................................................................................................................................................................................................................................................... 174
36 -13.600[UZ] KOG0073 GTP-binding ADP-ribosylation factor-like protein ARL2  ali follow..  20  19......................................................................................................................................................................................LLMLGLDNAGKTTILKKFNGEDIDT-----ISPTLGFNIKTLERGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSAD-CQRELQSLLVEERLAGATLLIFANKQDLPGASSNAIREALELDSIRSHHW----CIQGCSAVTGENLLPGIDWLL.................................................................................................................................................................................................................................................................................................................................................................................................... 173
37 -13.400[R] COG1100 GTPase SAR1 and related small G proteins  ali follow..  20  21......................................................................................................................................................................................ILILGLDGAGKTTILYRLQIGEVVT-----TKPTIGFNVETLSKNLKLNVWDLGGQTSIRPYWRCYYADTAAVIFVVDSTD-ASKELHLMLQEEELQDAALLVFANKQDQPGASASEVSKELNLVELKDRSW----SIVASSAIKGEGITEGLDWLIDVIKEEQL............................................................................................................................................................................................................................................................................................................................................................................................ 183
38 -13.300[U] KOG0077 Vesicle coat complex COPII, GTPase subunit SAR1  ali follow..  19  23......................................................................................................................................................................................ILFLGLDNAGKTTLLHMLKDERLVQHQP---TQHPTSEELSIGK--KFKAFDLGGHQIARRVWKDYYAKVDAVVYLVDAYD-SKRELDALLSDEALATVPFLILGNKIDIPYASEDELRYHLGLTNFTTGK-VRPLEVFMCSIVRKMGYGEGFKWLS.................................................................................................................................................................................................................................................................................................................................................................................................... 189
39 -13.200[R] COG1160 Predicted GTPases  ali follow..  12  4....................................................................................................................................................................................PVVALVGRPNVGKSTLFNRLRTRDALVADFPGLTRDRKYGHAHI-AGYDFIVIDTGGEEKMAEQSLLAIDEADIVLFLVDARAGLTAADIGIANYLQRQNKITVVVANKTD--GIDADSHCAEFYQLGL---------EIEQIAASQGRGVTQLMEQVLAPFAEKMENADENDRTS-IAIVGRPNVGKSTLTNRILGEDRVVVFD--MPGTTRDSIYIPMERDGQQYT-------IDTAGVRKRGKVHLAVEKFSVIKTLQAI-----QDANVVLLTIDARENISDQDLSLLGFILNAGRSLVIVVNKWDGLDQDVKDRVKSELDRRLDFIDFARV-HFISALHGSGVGNLFDSIKEACATQKMTTSLLTRILQMATDEHQPPMIGGRRIKLKY-----------AHPGGYNPPIIVVHGNQMDKLPDSYKRYLSNYYRKSLIIGSPIRLLFQEGSNP......................................................................................... 476
40 -13.100[R] KOG0393 Ras-related small GTPase, Rho type  ali follow..  16  6......................................................................................................................................................................................CVVVGDGAVGKTCLLLSYTTNAFPGEYILTVFDTYSTNVMVDGRPINLSLWDTAGQDDYDQFRHLSFPQTDVFLVCFALNENVRAKWYPEVSH-HCPNTPIILVGTKADLREDRDTIERLRESRLQPVSHTQGKAVKYLECSALTQIGLKQVFDEAIRTGLTPPQTPQTRAKKSNCTV............................................................................................................................................................................................................................................................................................................................................................................... 194
41 -12.800[R] KOG0395 Ras-related GTPase  ali follow..  21  22......................................................................................................................................................................................MVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDN--VKRLQKQILEVKSCELPMVICGNKNDHGEL--CRQVPTTEAELLVSGDEN--CAYFEVSAKKNTNVDEMFYVLFSMAK................................................................................................................................................................................................................................................................................................................................................................................................ 191
42 -12.700[R] KOG0091 GTPase Rab39, small G protein superfamily  ali follow..  18  12......................................................................................................................................................................................LILIGDSTVGKSSLLKFFTDGKFAELSDPTVGVDFFARLIEMKDGTQIKL-DTAGQERFRSITKRNSVGVLLVYDISNHAEHIPLWMMEAQRHIEPHRPVFALVGCKLDLINAGGHREVTTEEAQKFAKQH---GLHFVETSARSGANVEEAFRMVT.................................................................................................................................................................................................................................................................................................................................................................................................... 172
43 -12.500[R] KOG0394 Ras-related GTPase  ali follow..  19  11......................................................................................................................................................................................VIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVQFEDRLTLQIWDTAGQERFQSLGVRGADCCVLVYDVNSMKENLNNWREEFLIQASPSNFPFVLIGNKVDVDDGNSRVVSEKKAKA-----ASKGNIPYFETSAKVGTNVEEAFQCIA.................................................................................................................................................................................................................................................................................................................................................................................................... 173
44 -11.800[P] COG0370 Fe2+ transport system protein B  ali follow..  13  2..................................................................................................................................................................................SQNTYCILGNPNTGKTSLFNALTGSYEYVGNWSGVTKKVGTL-----RSKTGKLIDLPGIYDLNPISRDETVVTRFLCMLNIVDSSQIERNLNLTVQLLEYGAPVVMGLNMIDVAAGRGIHLNIQNLAKKL-------RIPILPVVARSGKGTEDILSTL---SEKHVAPAIPLVLQYGEPAEKAIKE--------------------------------------ALTKELIPAKQSRWLAIQFLSKNEVTEAFLTSNSAFEQLQQIRAELESELNGKLENHFHQVRASYIHDICLTSVEYTRNSDIPLSDKLDKIFTHKLLG-IFQITFTWVGAPLSDMLDGFIGGSLTDWVTSFLTTIGASGFIIDLVADGIIAGVGGVLVFVPQILVIFFFISV---------LEDSGYMARIAVVMDRVMEIF---------------LNGKAFIPMI--IGFGCNVPGIMAARSIEESKERTLTILVS................................................................. 426
45 -11.800[OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase  ali follow..  13  1................................................................................................................................................................................MKRPLIIGVGGPVGAGKTMLIERLYSMAAITNDIASMNFAAIEEMCDKHPDLQLLFLESGGDNLSATFSPDLVDFS-IYIIDVAQGEKIPRKGGQGMIKSD------LFIINKVDLAPY----VGANVEVMKADTLKSRGNKDFFVTNLKTDEGLKSVADWIEKRLQLALLE........................................................................................................................................................................................................................................................................................................................................................................................... 205
46 -11.500[R] KOG0080 GTPase Rab18, small G protein superfamily  ali follow..  19  11......................................................................................................................................................................................ILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKKLAIWDTAGQERFRTLTPRGAQGVILVYDVTRRDVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKH-------SMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKGVKLSHREEGQGG...................................................................................................................................................................................................................................................................................................................................................................... 196
47 -11.400[R] KOG0410 Predicted GTP binding protein  ali follow..  16  171........................................................................SGKVAEIKSAINALDVETVIFDDELSLRNLEKAFGGDVRVCDRTALILDIFNQRAATHEALQVALAQM---EVDKRILRTQIGVLKKELESVRKHRKQYRSRRVAIPVPVVSLVGYTNAGKSTLLNQLTGANVLAENRLFATLDPTTRRVQMQNGKEFLLTDTVGTTLVAAFRATLEEISSLLVHVVDISHPLAEQQIEAVEKVDVSSIPKLVVWNKVDRVDDPQKVKLEAEETGD-----------TICISALTGEGLDDFCNAVHEKLK-----------DSMVWVEALLPFDKGDLLSTIHKVGMV.......................................................................................................................................................................................................................................................................................................................................................... 500
48 -11.300[U] KOG0096 GTPase Ran/TC4/GSP1 (nuclear protein transport pathway), small G protein superfamily  ali follow..  17  15......................................................................................................................................................................................LVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFGEKFDVWDTAGQEKFGGLRDGYYINAQCAIIMF---DVTSRITYKNVPNRVCENIPIVLCGNKVDVKERKVKAKTITFHRKK--------NLQYYDISAKSNYNFEKPFLWLA.................................................................................................................................................................................................................................................................................................................................................................................................... 167
49 -11.000[U] KOG0094 GTPase Rab6/YPT6/Ryh1, small G protein superfamily  ali follow..  19  12......................................................................................................................................................................................LVFLGDQSVGKTSIITRFMYDKFDTTYQATIGIDFLSKTMYLEDRTRLQLWDTAGQERFRSLIPRDSSVAVVVYDVANRLS--TSKWIEEVRNERAGDVIIVLVGNKTDKRQVSIEEGDSKGREYGVM---------FIETSAKAGFNIKPLFRKIA.................................................................................................................................................................................................................................................................................................................................................................................................... 167
50 -10.900[U] KOG0092 GTPase Rab5/YPT51 and related small G protein superfamily GTPases  ali follow..  19  23......................................................................................................................................................................................LVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTKFEIWDTAGQERYHSLAPRGAQAAIVVYDITNEES--AKNWVKELQRQASPNIVIALSGNKADLANVDFQEAQSYADDNSLL---------FMETSAKTSMNVNEIFMAIALPKNEPQNPGANSARGRGVDLTEPTQPTRNQCCS.................................................................................................................................................................................................................................................................................................................................................................. 214
51 -10.900[R] KOG0088 GTPase Rab21, small G protein superfamily  ali follow..  16  15......................................................................................................................................................................................IVLLGEGCVGKSSLVLRFVENKFSCKHLSTIQASFQNKTVNVEDCQDLHIWDTAGQEKYHALGPRGSNGVLLVFDITDRKS--VKNWVLEIKTCLGNTAEILIVGNKIDLEE------ERQVTRQDAEAYAESEGALYMETSAQDNVGISDAFESLT.................................................................................................................................................................................................................................................................................................................................................................................................... 170
52 -10.700[T] KOG4252 GTP-binding protein  ali follow..  17  12......................................................................................................................................................................................MVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDRLMLWDTAGQEEFDAITKRGAQ----CVLVF---STTDRGSFEAVSSAEVGDIPTVLVQNKIDLLDIKNEEAEALAKRLRL---------RFYRTSVKEDLNVNEVFKYLA.................................................................................................................................................................................................................................................................................................................................................................................................... 166
53 -10.500[U] KOG0086 GTPase Rab4, small G protein superfamily  ali follow..  19  11......................................................................................................................................................................................FLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTKLQIWDTAGQERFRSVTRRGAAGALLVYDITSRET--LAAWLTDARTLASPNIVVILCGNKKDLDP------EREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCA.................................................................................................................................................................................................................................................................................................................................................................................................... 166
54 -10.500[U] KOG0097 GTPase Rab14, small G protein superfamily  ali follow..  21  14......................................................................................................................................................................................YIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKKLQIWDTAGQERFRAVTRRGAAGALMVYDITRRST--LSSWLTDARNLTNPNTVIILIGNKADLEAVTYEEAKQFAEENGLL---------FLEASAKTGENVEDAFLEAA.................................................................................................................................................................................................................................................................................................................................................................................................... 169
55 -10.500[U] KOG0098 GTPase Rab2, small G protein superfamily  ali follow..  22  9......................................................................................................................................................................................YIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVTIDGKQKLQIWDTAGQESFRSITRRGAAGALLVYDITRRDT--LTSWLEDARQHSNSNMVIMLIGNKSDLEAVKREEGEAFAREHGLV---------FMETSAKTAANVEEAFIDTA.................................................................................................................................................................................................................................................................................................................................................................................................... 164
56 -10.400[U] KOG0087 GTPase Rab11/YPT3, small G protein superfamily  ali follow..  17  13......................................................................................................................................................................................TVLIGDSGVGKSNLLMRFTRNEFNIESKSTIGVEFATRNIVLDNKKKAQIWDTAGQERYRAITSRGAVGALIVYDITKQSS--VGRWLKELREHADSNIVIMLVGNKTDLLHVSTEEAQAFAAENNL---------SFIETSAMDASNVEEAFQTVL.................................................................................................................................................................................................................................................................................................................................................................................................... 168
57 -10.400[U] KOG0095 GTPase Rab30, small G protein superfamily  ali follow..  19  12......................................................................................................................................................................................IVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVGFMIKTVEINGEKKLQIWDTAGQERFRSITQRSANALILTYDITCEES--LPEWLREIEQYASNKVITVLVGNKIDLAEVSQQRAEEFSEAQDM---------YYLETSAKESDNVEKLFLDLA.................................................................................................................................................................................................................................................................................................................................................................................................... 167
58 -10.300[U] KOG0081 GTPase Rab27, small G protein superfamily  ali follow..  17  12......................................................................................................................................................................................FLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGHLQLWDTAGQERFRSLTTRDAMGFLLLFDLTNEQLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDVKEEEAIALAEKYGI---------PYFETSAANGTNISQAIEMLL.................................................................................................................................................................................................................................................................................................................................................................................................... 178
59 -10.200[U] KOG0093 GTPase Rab3, small G protein superfamily  ali follow..  16  25......................................................................................................................................................................................ILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRKLQIWDTAGQERYRTITTRGAMGFILMYDITNEES--VQDWSTQIKTYSWDNAQVLLVGNKCDMEDVSSERGRQLADHLGF---------EFFEASAKDNINVKQTFERLV.................................................................................................................................................................................................................................................................................................................................................................................................... 180
60 -10.200[J] KOG1191 Mitochondrial GTPase  ali follow..  15  258.........................................................................................RLDLSQAENVEKLISAKSSAAADAALEGIQGGFSSLVKSLRAQC-IELLTEIEARLDFEDEMPPLDIESVINKITSMSQDTANYDKLLQSGLQIAIVGRPNVGKSSLLNAWKSERAIVTEVAGTTRDVVEANVTV-RGVPITLLDTAGRETNDIVEKIGVERSDVIIMAVSAVEGWTEEDTELLRKIQSLKQPMILVMNKIDCAPPGSCDQLEDQRKKEEVFHK------SVFTSAVTGQGIEELEDAILEILGLDRVPTGGHQWTVNQRQCEQLVRTKEALVRLREAIEDEIPID-FWTIELREAALSLAQISGQDVSE.............................................................................................................................................................................................................................................................................................................................. 599
61 -10.200[R] KOG0083 GTPase Rab26/Rab37, small G protein superfamily  ali follow..  20  471......................................................................................................................................................................................VIMLGDSGVGKTSLLIRFRDGRYVPSYF-GIDFRNKVVVV---DGTRVKL-DTAGQERFRSVTHRDAHAL-LLLYDVTNKTTYIRAWLGEIREYAQEDVVIVLIGNKADCSGSE-RQVKREDGER--LGREHN--VPFMETSAKTGLNVELSFTAVARQLKSRGYEHGDDGKFNVHDFVRDNTKARSVCAQC................................................................................................................................................................................................................................................................................................................................................................. 663
62 -9.850[TU] KOG0084 GTPase Rab1/YPT1, small G protein superfamily, and related GTP-binding proteins  ali follow..  20  11......................................................................................................................................................................................LLLIGDSGVGKSCLLLRFADDSYLDSYISTIGVDFKIRTVEQDGKTKLQIWDTAGQERFRTITSRGAHGIIVTYDVTDLES--VKQWLNEIDRYASENVNKLLVGNKCDLTSVSTETAKAFADELGI---------PFLETSAKNATNVEEAFMAMT.................................................................................................................................................................................................................................................................................................................................................................................................... 166
63 -9.800[TU] KOG0078 GTP-binding protein SEC4, small G protein superfamily, and related Ras family GTP-binding proteins  ali follow..  16  12......................................................................................................................................................................................LLLIGDSGVGKSCLLLRFSEDSFTPSFITTIGIDFKIRTIELDGKRKLQIWDTAGQERFRTITTRGAMGILLLYDVTDKKS--VRTWFSNVEQHASENVYKILIGNKCDCEDVSFEQGQALADELGV---------KFLEASAKTNVNVDEAFFTLAREIKKQKIDAENEFSNQANNVDLGNDRTVKRCC................................................................................................................................................................................................................................................................................................................................................................... 200
64 -9.720[R] KOG1673 Ras GTPases  ali follow..  14  104......................................................................................................................................................................................ISLLGDCQTGKTTFV-----VKYVGDENQSFLEMTGL-TFYVQGVTSFSIWDVGGDEDHIPIACKDAVA---ILFMF---DLTSRSTLNSVFRKWNKTAIPILIGTKFDDFVRLPPNLQWTIVTQARAYAK---NASLFFSSATHNINVNKIFKFILARLFNLPWKIDRNLTLGEPIIDYD............................................................................................................................................................................................................................................................................................................................................................................ 287
65 -9.710[R] COG2262 GTPases  ali follow..  15  60........................................................................EGKAVEIAEAVKATGASVVLFDHALSERNLERLCECRVIDRTGLILDI-FAQRARTHEGKLQVELAQL---ETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRITEARVYAADQLFATLDPTLRRIDVADVGETVLADTVGHDLVAAFKAQETRQATLLLHVIDAADVRVQENIEAVNTVDAHEIPTLLVMNKIDMLEDFEPRIDRDEENKP----------IRVWLSAQTGAGIPQLFQALTERLS-----------GEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSVSLQVRM......................................................................................................................................................................................................................................................................................................................................... 406
66 -9.530[R] KOG0079 GTP-binding protein H-ray, small G protein superfamily  ali follow..  18  13......................................................................................................................................................................................LLIIGDSGVGKSSLLLRFADNTFSENYITTIGVDFKIRTMDINGQRKLQIWDTAGQERFRTITSRGTHGVVVVYDVTNGEGNVKRWLQEIENNCD--SVQKVLVGNKCEENEVLESDARNYAQSMNI---------SFFETSAKEDKNVEPMFTCIT.................................................................................................................................................................................................................................................................................................................................................................................................... 167
67 -9.230[R] KOG1490 GTP-binding protein CRFG/NOG1 (ODN superfamily)  ali follow..  12  169....................................................................................................................................................................................RTVLICGYPNVGKSSFMNKVTRADVDVQPYAFTTKFVGHTDY---KYLRYQVIDTPGFEDRNIIEMCSAHLRAAVLFFLDISGSCGYTIAQQAALFHSMNKPLVIVCNKTDLMPME-KLIEEMKSEAMKTAMGASEEQVLLKMSTLTDEGVMSVKERLLDQRVEAKMKSKKINDHLNRFHVAIPKPRDSIERLPCIPQVVLEAKAKEAAAMEKRKTEKDLEEENQHDEWKEDIMPEILDGHNVA-----DFIDPDILQRLAELEREEGIREAGVEEADMEMDIEKLSDEQLKQLSEIRKKKAILIKNHRLKKTVAQNRSTVPRKFDKDKKYTTKRMGRELSADPSSAMDRARSKSRGRKRDRSEDAGNDAMDVDDEQQSNKKQRVRSKS-----RSQSRPPAHEVVPGEGFK-----------DSTQKLSAIKISNKSHKKR-GEAD-----VIPTLRPKHLFSGKR-GKGKTDRR....................................................................... 671
68 -9.070[TU] KOG1954 Endocytosis/signaling protein EHD1  ali follow..  17  44.................................................................................................................................SKKKNKEVLETVSEGLRKIYKQKLLPLEEFHKFHDFHSPALDDPD---DAKPMILLVGQYSTGKTTFIRYLLESDFPGIRIGAFLNRFQCSTLPNQVLESVTIVDTPG-SGEKQRIDRGAERVDRIILLFDAHKDISDEFKRCIEALAGNEDKIRIVLNKSDMDHQQLMRVYGALM-WSLGKVFKTPEVSRVYLGSFWDHPLHYDLNRRLFQDEQHDLFQDLQALPR................................................................................................................................................................................................................................................................................................................................................................................... 321

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Bossy-Wetzel E, Barsoum MJ, Godzik A., Schwarzenbacher R, Lipton SA. Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr Opin Cell Biol. 2003 Dec;15(6):706-16. Review.