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Query: [R] KOG1334 WD40 repeat protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPGLKAAICADDLIVMVVASLILATQNPDSVQPFGYCSGAKKLSDVRILWRTIGASEVKLFPYRDKNDHQHLPEGVSNKDFQSGATRKLLLPGVPDQLQQTSFEMSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFLNDASTENQNTDSESSSEDVELESMGEGLFGYPLPRMCPRCGGTNHDQCLLDEDQALEEWISSETSALPRSRWQVLTALRQRQLGSSARFVYEACGARTFVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEPHPYLPVLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNLNYTDSFDNRMLRFFVRHLLQRAHQPGWRDHGAEFPDEEELDESSSTSDTSEEEGQDRVQCIPSLast
1 -218.000[R] KOG1334 WD40 repeat protein  ali  100  1MPGLKAAICADDLIVMVVASLILATQNPDSVQPFGYCSGAKKLSDVRILWRTIGASEVKLFPYRDKNDHQHLPEGVSNKDFQSGATRKLLLPGVPDQLQQTSFEMSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFLNDASTENQNTDSESSSEDVELESMGEGLFGYPLPRMCPRCGGTNHDQCLLDEDQALEEWISSETSALPRSRWQVLTALRQRQLGSSARFVYEACGARTFVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEPHPYLPVLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNLNYTDSFDNRMLRFFVRHLLQRAHQPGWRDHGAEFPDEEELDESSSTSDTSEEEGQDRVQCIPS 681
2 -99.000[S] KOG0293 WD40 repeat-containing protein  ali follow..  16  9.PPLKRA--------KRLADEPNGFSANSSVRGSSVNSNSLGDLMARPLPSQGDDETIGSKGVIRKSEFVRIITRALYSLGYDKTGAMLEEES--GISLHNSTIKLFLQQVKDGKWDQSVKTLHRIG----PDEKAVKAASFLLLEQKFLEFLKVEKIADALRTLRNEMAPLRIN-TKRVHELASSLISPSSFISHTTSTPGKESVNSRSKVLEELQTLLPASVIIPEKRLNSLHIQRDSCVFHNTLDSDLSLYSDHQCGKHQIPS-QTAQILESHTDEVWFLQFSHNGKYLASSSKDQTAIIWEISADGSLKHTLVGHHKPVIAILWSPD--DRQVLTCGAEEVIRRWDVDSG---DCVHMYEKGGISPISCGWYPDG-QGIIAGMTDRSICMWDLDGRE-----KECWKGQRTQKVSDIAMTDDG-KWLVSVCKDSVISLFDREATVE---------------RLIEEEDMITSFSLSNDNKYILVNLLNQEIRLWNIEGDP--KIVSRYKGHKRSRFIIRSCFGGYKQAFIASGSEDSQVYIWHRSTGKLIVELPG-HAGAVNCVSWSPTNLMLASASDDGTIRIWGLDRINQKKKLVQGSSSNGVIHRCNGN................................................................. 589
3 -86.100[R] KOG1310 WD40 repeat protein  ali follow..  24  1...................................................................................................................................................................................................................................MDNLSFHDGNIFNLLHTRSQDPSHEVDQRMQFHSSLVRRLSQEQELEGHQGCVNALAWNSNGSLLISGSDDLRINIWNYSSRKLLHSIDTGHTANIFCTKFVPETSDELVVSGAGDAEVRLFNTSRLSG-IPSALYQCHTRRVKKLAVEPGNPNVVWSASEDGTLRQHDFRESTSCPPRALADPPKQTLSLKSCDISATRPHLLLVGGSDAFARLYDRRMLPPLASSRKRMPPPPCVNYFGRTNLHLTHVTFSPNGEEVLLSYSGEHVYLMNVNNGTAIDMKRRYVGHCNVGTIKQASFLGQRGEYIASGSDDGRWFIWEKQTGRLMKVLVG-DESVLNCIQCHPFDSVVATSGIDNTIKIWSPTASVSIVAGGSAGPATANVVEVMESNQQKLSRNRENPLSVELMQRFRMQ--------------------------EFAEGNFHPFECTQS 754
4 -75.000[R] KOG4227 WD40 repeat protein  ali follow..  18  1................................................................................................................................................................................................................................MKRRAGLGGSMRSVVGFLSQRGLHGDPLLTQDFQRRRLRGCRNLYKKDLLGHFGCVNAIEFSNNGQWLVSGGDDRRVLLWHMEQAVKPIQLKGEHHSNIFCLAFNSG--NTKVFSGGNDEQVILHDVESSE----TLDVFAHEDAVYGLSVSPVNDNIFASSSDDGRVLIWDIRESPHGEPFCL---ANYPSAFHSVMFNPVEPRLLATANSKEGVGLWDIRKPQSSLL----------RYGGNLSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHSRLPV-FQFDNQGYFNSCTMKSCCFAGDRDQYILSGSDDFNLYMWRIPADPEAGMVLKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSPYKQPTGDLDGRIEDDSRCLYTHEEYISLVLNSGSGLS--SVQEDPRMMAFFDSLVRREIEGWSSDSDSDLSESTILQLHAGVSE...... 452
5 -73.900[ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA cleavage factor II complex, subunit SWD2  ali follow..  20  9......................................................................................................................................................................................................................................................................VVRSFKVAKIFRENTDKINAIDFAPNGEHLISCSEDDQIVIYDCEKGTQSRTV-NSKKYGVDLIHFTHANNTAIHSSTKVDDTIRYLSLHDN---KYLRYFPGHTKKVISLCISPVE-DTFLSGSLDKTLRLWDLRSPNCQGLM-------HLSGRPIAAYDPEG-LIFAAGVNSESIKLYDLRSFDKGPF--------VTFKLNQEKECDWTGLKFSRDGKTILISTNGSVIRLVDAFHGT---PLQTFTGYPNNKGIPIEASFSPDSQFIFSGSTDGRVHIWNADTGNKVSVLNGDHPGPVQCVQFNPKYMMLASACTNMAFWLPTSEE........................................................................................ 315
6 -69.500[D] KOG0642 Cell-cycle nuclear protein, contains WD-40 repeats  ali follow..  12  49LPGIRAELQAKDLVIKMLEYALKQERAKYHKYGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALDVTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESAAADFSDEDEDDDVDGREKSVIDTSTIVRKVTSEEGDNESRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKRPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSGKSFIMGADEALESELGPGELNPKFTLRSHFDGIRALAFHPI--EPVLITASEDHTLKMWNLQKTADVEPIYTFRAHKGPVLCVVMSSNG-EQCYSGGTDGLIQGWNTTNPNYDPSVLRGPLLGHTDAVWGLAYSAAHQ-RLLSCSADGTLRLWNTTEVAPALSV---------FNDIKELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNVDTANSSCQINRVISHPTLSISITAHEDRHIKFYDNNTGKLIHSMVA-HLEAVTSLAVDPNGLYLMSGSHDCSIRLWNESKTCIQEFTAHEESIHDVAFHPSKCYIASAGADALAKVF................................................... 779
7 -65.800[R] KOG0289 mRNA splicing factor  ali follow..  11  83.............................................................................................................................................................................................................................DAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARLTKEVTAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQKL--QDKATVLTTERKKRG------KTVPEELVKPEELSKRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSSEQ-----ILATLKGHTKKVTSVVFHPSQD-LVFSASPDATIRIWSVPNASC-------------VQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDE----TSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG-HSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLK............. 500
8 -65.700[S] KOG4328 WD40 protein  ali follow..  11  6..............................................................ERKRLENIRRNDEMLAALNVRAKASSLLSAAKRSRDDSKSFKKKKPKPASTPTVIRMSLRTRGLNPDSAGLPDGFSDFRMGSQITHNQPSPQKQSPRLLAPIPFESAYEGYGSYTQLVDTLL------GIESKSCRGKLVKGEIGVVKDENESPMVRTRSSSRVSKVSVKKEEPEDDSFSDYVNKEFSIPVKPEKIEFDLDLLTLEPQNVARVVPGRIFVVQFLPNVKMVAAGDKLGNVGFWNLDCGNEEIYLFTPHSAPVSSIVFQQNSL-SRVISSSYDGLIRLMDVEKS----VFDLVYSTDEAIFSLSQRPNDEQSLYFGQDYGVFNVWDLRAGKS-----VFHWELHERRINSIDFNPQNPHVMATSSTDGTACLWDLRSMGAKK---------PKTLSTVNHSRAVHSAYFSPSGLSLATTSLDNYIGVLSGANFENTCMIYHN--NTSRWISKFKAVWGWDDSYIYVGNLSKKIDVINPKLKRTVMELHNPLRAIPCRIHCHPNVGTLAGSTAGGQVYVWTTK......................................................................................... 516
9 -65.200[S] KOG0310 Conserved WD40 repeat-containing protein  ali follow..  13  17...........................................................................................................................................................................................................................................................................ETILLDEDEPAVVSSVRISPKKPYHVATTSSVRLTLYDTVVCEPLNLF-SRFKKGVCSIDFRHD--GRLLAIGGDEGKVRIFDVETGSSKVALRVMQASQSTVKSVHFSPRG-DTVFSMADDGKIKQYRVADTAYVNAVPIIEIQAHEDAIRCGAVSSINDHIVLTGGYDHKVRLWDIRSKEKSLEL--------------DCEHPVESVLFLPGEQ-LIATAAGPIVKIWDTTTGRQLTALQAHYK------TVTSLRLATNSTCLLSAGIDRRVNAFRTTNYSLINSW--SMPSPVLDIDVSRDDQTMAIGMGNLLALYRREIKKEATASAAIEDKRSLIRTSAPPVKLVEKDRDMQKVDVVAKNAKLKIPKIDGMLSNFKHAAVIKLLFGGK................... 389
10 -63.600[S] KOG0282 mRNA splicing factor  ali follow..  11  1.............MSAAIAALAASYGSGSGSESDSDSESSRCPLPAADSLMHLTKSPSSKPSLKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFATYGYALDPSLDNHQVSAKYIGSVEEAEKNQGLTVFETGQKKTEKRKKFKENDYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPK-KQIHVWSGHTKGVSAVRLFPLGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTA--GTQFLSAAYDRYLKLWDTETGQCISRFT----NRKVPYCVKFNPDEQNLFVAGMSDKKIVQWDIRSGE-----IVQEYDRHLGAVNTIVFVDEN-RRFVSTSDDKSLRVWEWDIPVDFKY------------IAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGH-MVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKA-HDKVCIGAVWHPETSKVITCGWDGLIKLWD........................................................................................... 579
11 -63.200[A] KOG0265 U5 snRNP-specific protein-like factor and related proteins  ali follow..  19  12....................................................................................................................................................................................................................................LAQEAKRSKNDLMAYTNRDKALLESGVRRTSNLQ-----APIMQLEGHEGEIFTAEFHPEGELLLSSGFDRQIYIWQVYEDCENVMAMSGHSGAVMEAHFTPD--GSHIFTCSTDKTLAFWDIATG---QRQRRFKGHGNFVNSVQGSRRGQQLLCSGSDDRTIKIWDARKKHAAHTL------ESPFQVTAVCFGDTG-EQVISGGIDNEVKIWDIRKQAVLHH-------------LRGHSDTITGMSLSPEGDFILTNAMDNTLRVWDVRPAPGERCVKVFQGHQHNEKNLLRCAWSPGSDKITSGSADRHVYIWDVNTRRILYKLPG-HNGSVNAVDFSPKEPLILSGSSDKTLYLGEID......................................................................................... 346
12 -62.700[U] KOG1332 Vesicle coat complex COPII, subunit SEC13  ali follow..  16  5............................................................................................................................................................................................................................................................................INTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREENGT--EKSHEHAGHDSSVNSVCWAPHDGLILACGSSDGAISLLTYTGEGQWE--VKKINNAHTIGCNAVSWAPAVVKRFASGGCDNLIKLWKEEEDGQ-----------KEEQKLEAHSDWVRDVAWAPSI--------------------------------------------GLPTSTIASCSQDGRVFIWTCDDASWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVVCISDVNKGQGSVSSVTEGQQNEQ................................................................ 322
13 -62.600[U] KOG0276 Vesicle coat complex COPI, beta` subunit  ali follow..  12  1......................................................................................................................................................................................................................................................................MPLRLEIKRKLAQRSERVKSVDLHPTEPWILASLYSGTLCIWNYQTQVMAKSF-EVTELPVRSAKFVAR--KQWVVAGADDMYIRVYNYNTM---DKVKVFEAHSDYIRCVAVHPTLP-YVLSSSDDMLIKLWDWEKGWA----CTQIFEGHSHYVMQVTFNPKDTNTFASASLDRTIKIWNLGSPD-------------PNFTLDAHQKGVNCVDYFTGGDKLITGSDDHTAKVWDYQTKSCVQTLEGHTHN------VSAVCFHPELPIIITGSEDGTVRIWHATTYRLENTLNY-GLERVWAIGYIKSSRRVVIGYDEGTIMVKLGREIPVASMDNTGKIIWAKHNEIQTANIKSIGADYEVTDGERLPLVKELGTCDLYPQSLKHNPNGRFVVVCGDGE................ 375
14 -62.500[A] KOG0647 mRNA export protein (contains WD40 repeats)  ali follow..  12  3...........................................................................................................................................................................................................................................................................................FFNRSNTTSALGTSTAMANEKDLAND---IVINSPAEDSISDIAFSPQQD-FMFSASSWDGKVRIWDVQNGV--PQGRAQHESSSPVLCTRWSNDG-TKVASGGCDNALKLYDIASGQ------TQQIGMHSAPIKVLRFVPSNTECIVTGSWDKTIKYWDMRQPQPVSTV--------------MMPERVYSMDNKQSLLVVATAERHIAIINLANPTTIFKATTSPLKWQ------TRCVACYNEADGYAIGSVEGRCSIRYIDDGMQKKSGFSSLVYPVNSIAFHPLYGTFVTAGGDGTFNFWDKQRHRLKGYPTLQASIPVCSFNRNGSVFAYALSYDWHQGHMGNRPDYPNVIRLHATTDEEVKEKKKR........................ 365
15 -62.500[S] KOG0270 WD40 repeat-containing protein  ali follow..  13......................................................SSEFPEKYVLDDEEVERINQLAQLNLDDAKATLEEAEGESGVEDDAATGSSNKLKDQLDIDDDLKEYNLEEYDDEEIADNEDVSMFPGLSNDSDVKFHEGEKGEDPYISLPNQEDSQEEKQELQVYPSDNLVLAARTEDDVSYLDIYVYDDGAGFHSSDIPVEEGDEADPDVARGLVRDPALYVHHDLM-----------------------LPAFPLCVEWLDYKVGSNSEEAANYAAIGTFDPQIEIWNLDCVDKA-------------------FPDMILGEPLDNSMVSLKSKKKKKKSKTGHITTHHTDAVLSMAHNKYFRSVLASTSADHTVKLWDLNSGNAARSL---ASIHSNKNVSSSEWHMLNGSILLTGGYDSRVALTDVRISDESQMS---------KYWSAMAGEEIETVTFASENI-ILCGTDSGNVYSFDIRNNENRKPVWTLKAHDAG---ISTLCSNKFIPMSTGAMGEKTVKLWKFPLDDATNT-RDFDVGNVLTSSFAPDIETMVIGGVNKVLKLWDVFTNRRKSFKSELENVQARAKEEAQKIGKSSRIARKYTSNDNPDTTIDDQGEDEEEREGGDEHDDM......................... 575
16 -61.800[A] KOG0268 Sof1-like rRNA processing protein (contains WD40 repeats)  ali follow..  12  49...................................................................................................................................................................................................................................................................KLERVFAKPFLASLDGHRDGVNCLAKHPEKATVLSGACDGEVRIWNLTQRNCIRTI-QAHEGFVRGICTRFC--GTSFFTVGDDKTVKQWKMDGPGYGDEEEPLHTILGKTVYTGIDHHWKE-AVFATCGQQVDIWDEQRTNP-----ICSMTWGFDSISSVKFNPIETFLLGSCASDRNIVLYDMRQATPLKKV--------------ILDMRTNTICWNPMEAFIFTAANDYNLYTFDMRALD--TPVMVHMDHVSA---VLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSREVYHTKRMQHVICVKWTSDSKYIMCGSDEMNIRLWKAASEKLGVLTSREKAAKKFQHYPHIKRIA-RHRHLPKSIYSQIQEIMKEARRRKEVNRIKHSKPGSVPLVSEKKKHV.............. 440
17 -61.700[S] KOG0271 Notchless-like WD40 repeat-containing protein  ali follow..  14  92.......................................................................................................................................................................................................................................................................RPVTRCSASIPGHGEPVISAQFSPDGRGLASGSGDQTMRIWDIELELPLHTC-KSHKSWVLCIAWSPD--ATKIASACKNGEICIWNAKTGE--QIGKTLKRHKQWITSLAWQPMTCRLLASCGKDGNIFIWDTVQGT-----VVRCLSGHTASVTCLRWGGEG--LIYSGSQDRTVKMWRADDGV-------------MCRNMTGHAHWINTLALNTDYALRTSCFEPSKRCIKPDTVEECQKVAQTR---------YEAALEIAGGERLVSGSDDFTLFMWNPKETKQSINRMTGHMQLVNQVVFSPDTRYIASASFDKSVKLWCGTGKYLASLRGHVGPVYQVAWSADSRLLVSGSADSTLKVFELKTKYYDLPGHGDEVFTVDWSPEGTKVVSGGKDKVLK............. 469
18 -61.000[Z] KOG0313 Microtubule binding protein YTM1 (contains WD40 repeats)  ali follow..  14  95..............................................................................................................................................................................................................................................................................EQCMFHDDWISSIKGAEEW--ILTGSYDKTSRIWSLEGK--SIMTIVGHTDVVKDVAWVKKDSSCLLLSASMDQTILLWEWNVERKVKALHCCRGHAGSVDSIAVDGSG-TKFCSGSWDKMLKIWSTVPTDEEDEMEIVTLSGHMEAVSSVLWSDAE--EICSASWDHTIRVWDVGSGSLKSTL--------------TGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTG----VTSVKWSPTHEQLISGSLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKLYSYRYSPTT...................................................................................... 418
19 -60.900[A] KOG0299 U3 snoRNP-associated protein (contains WD40 repeats)  ali follow..  11  14.....................................................................................................................................................................RKARSATSKREKENQKLERNGPANEDLASISSESEFNGFEDEIDEENEDTYETAAEKRLRLAREYLDEVKNELASRLKEDVLEKKGQMYLDYTSKINPDVKIETAQLRGRHMRPLVGVVAYENF--VYSADKSGLIQKWEALQEKDTENRENDHVKEITCLAISND--GRWIVTGGLDHRIVIRDSVTL---EPQHCWKHHRDAVMGLAMRRGT-NEMFSCSADRSIKVWSLDQMS-----YIETLFGHQDVIFGVDALARE-RCVSVGGRDRTSRLWKIVEESQLVFRSGGT----SMKATAGYMEGSVDCVAMIDEDHFVTGSDNGVIALWSVQRKKPLFTYPLAHG-PPQPRWITSLAAIPYSNLFASGSWDGNIRLWKIAEGLRSFEPLTSVYGCINSLSLSLQGKVFAACGRETRVGRWKTLRGIPNSGFVFNIPLTVIPSVTDGDEID.............................................................. 523
20 -60.500[S] KOG0296 Angio-associated migratory cell protein (contains WD40 repeats)  ali follow..  13  27..................................................................................................................................................................................................................................................LMDQGVTEDEAEQEQNDTMNNMVMDMSVQGFFEHKDSVFSVSINPVHNLCASGGGDDLGYIWDITTGEQICQL-TGHKDSIVAIDWSFD--GTYIATGGMDSQVRLWKSSTG---FEFITAFETVDEIVWLSWHPKG-LFLAAGCNDGSIWMWSLPSGK-----VVQVMYGHTAPVNAGKFIPPGVKRLATVDDSGTLIVWNPATGAPECRMSSDD--HRFDPGNEETAAGWTSFDCNAEGNVLFLGGSSGKVKVVNINSSHILASLEAQTES------VEAIALCTALPICACASVDGTVALYDSASLKFRKSL--PHEQAVIDCKFLPNTPYLLTACADCVIRKWDVSGQLLGEYTGHQEPILCMAITPDGKRVVTGSDDTELLVFDCEH............................................... 399
21 -60.100[S] KOG0316 Conserved WD40 repeat-containing protein  ali follow..  18  9...........................................................................................................................................................................................................................................................................KEAHILKGHEGAVLAARFNGDGNYALTCGKDRTIRLWNPHRGILIKTY-KSHGREVRDVHVTSD--NAKFCSCGGDRQVYYWDVSTG---RVIRKFRGHDGEVNAVKFNDSS-SVVVSAGFDRSLRVWDCRSHS-----VEPVQIIDTFLDTVMSVVLTKTE-IIGGSVDGTVRTFDMRIGR---------------EMSDNLGQPVNCISISNDGNCVLAGCLDSTLRLLDRTTGE---LLQVYKGHISKSFKTDCC-LTNSDAHVIGGSEDGLVFFWDLVDAKVLSKFRAH--DLVNSIDVDFYLRKFFVAGDKRELPPEGRYVDFFGRWYNSCLEMKKQQILTSIDFVIYVSNSPFFFYYRL................................................. 343
22 -60.000[Z] KOG1523 Actin-related protein Arp2/3 complex, subunit ARPC1/p41-ARC  ali follow..  13  1.............................................................................................................................................................................................................................................................................MSLHQFLLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQVKAHELKEHNGHITGIDWAPK--SDRIVTCGADRNAYVWSQKDGV--KPTLVILRINRAATFVKWSPLE-NKFAVGSGARLISVCYFEAEND---VSKHIKKPIRSTVLSLDWHPNN-VLLAAGSCDFKCRVFSAYIKEVDEKKASTPWGSKMEFGGSGTGGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLKTEFL-------LLSVSFVSENSVVAAGHDC-CPMLFIYDDRGCLTFVSK-HQNSITQVSIKQDCRKFCTTGIDGAMTIWDFKTLE...................................................................................... 361
23 -59.900[S] KOG1409 Uncharacterized conserved protein, contains WD40 repeats and FYVE domains  ali follow..  19........................................................................................................................................................................................................................................................................AKPALLHRITGHVARINDVILLSKDEGVWTASDDRSVRLYLKRDNDQFWPIHHFMPVAPTSLYYSEE--TYKLLVGLINGNVYEFSVADDNSMTESRKWTCHAGPISGLGFALSS-ELIFSCSRDKSIVWHCSENSNK--------MGSYLLENSCTAMVIDLPF-VFVGDHGGHVTVLRIVDNQP-----------NLVSKLSAHTNAITSLTWDGNKKVLYSGSSDHLIIMWDIGGGR--GEAYELNGHNGK---VTTLCAAPAAKRLFSADEHGKLMCWDMNCKRVETPEWKTTCGSAVCGSCCDNWTTYPPMGYETKIRICNDNLTPLAIPHEIHTGITAMHLQETLGLLVTSGQNRVIMIWDVRSVCSAPSGSQ...................................... 415
24 -59.800[YU] KOG2445 Nuclear pore complex component (sc Seh1)  ali follow..  11  1............................................................................................................................................................................................................................................................................MQPFDSGHDDLVHDVVYDFYGRHVATCSSDQHIKVFKLDKDTELSDSWRAHDSSIVAIDWASPEYGRIIASASYDKTVKLWEEDPDQEENKLCTLNDSKGSLYSVKFAPAHGLKLACLGNDGILRLYDALEPSDLRSVLSIPPANHLQSDFCLSWCPSRFSEKLAVSALEQAIIYQRGKDGK-----------HVAAKLPGHKSLIRSISWAPSYQLIATGCKDGRIRIFKITEKLSPLASEESLTN------SNMFDNSADVDMDAQGRSDSNT-LQSNLQVELLSEHDD-HNGEVWSVSWNLTGTILSSAGDDGKVRLWKATYKCMSVITAQQ.............................................................................. 349
25 -59.300[S] KOG1407 WD40 repeat protein  ali follow..  15  13.............................................................................................................................................................................................................................................................................SREYQGHKKKVHSVAWNSNGTKLASGSVDQTARIWNIEPHGAKDLELKGHTDSVDQLCWDPK-HSDLVATASGDKSVRLWDARSGKCTQQV----ELSGENINITYKPDG-THVAVGNRDDELTILDVRKFKPLHRR------KFNYEVNEIAWNMPGD-FFFLTTGLGTVEVLSYPSLK-------------PLDTLTAHTAGCYCIAIDPKGRYFAVGSADSLVSLWDISDMLCLRTFTKLEW-------VRTISFNYSGEYIASASEDLFIDIANVQTGRTVHQIPCR--AAMNSVEWNPKYNLLAYAGDDKNPKYNTDEG........................................................................................ 305
26 -59.200[T] KOG4378 Nuclear protein COP1  ali follow..  10  1.......................................................................................................................................................................................................................................................................................MMSNLVEPSWRLLAASGGD-TVKLFDVSADSCVLSYTPSPGCAVNSVKWNHT--NLVVASTGEDKKISLWRKNGQSLGTVKDGGDSAEECLSAISFSKKGSRYICSGGTGQIVKIWDLQRKL-----CIKKLKGHTSTITGVMYNCKDEH-LASVSVGGDLIVHNLASGARATELKDPNG------QVVQFVHVLRLLDYSRSSRHL-----------------------------------------------LVTAGDDGTVHLWDTTGRSPKMSWLKQHSAPTAGVCFSPSNEIIASVGMDKKLYTYDSGSRRSSSCIAYEAPFSSLAFGDNGYILVAGTSNGRVVFYDIRGTVLHAFSNSEDVTSLSWQTSKPVIVNEKNYTSE.............. 339
27 -59.100[JT] KOG0643 Translation initiation factor 3, subunit i (eIF-3i)/TGF-beta receptor-interacting protein (TRIP-1)  ali follow..  15  5...............................................................................................................................................................................................................................................................................LLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTY-MGHTGAVWCVDADWD--TKHVLTGSADNSCRLWDCETGKQLALL----KTNSAVRTCGFDFGGNIIMFSTDKQCFVSFFDLRDSQIDNNEPYMKIPCNDSKITSAVWGPLG-ECIIAGHESGELNQYSAKSGEVLVN-------------VKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTF-------RTERPVNSAALSPNYDHVVLGGGQEAARFFHLAFEEEFGRVKG-HFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQY...................................................................................... 318
28 -58.900[R] KOG0286 G-protein beta subunit  ali follow..  16  8...................................................................................................................................................................................................................................RQEAEQLKKQIADARKACADVTLAELVSGL--EVVGRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAI-PLRSSWVMTCAYAPS--GNFVACGGLDNMCSIYNLKSRENVKVSRELSAHTGYLSCCRFLDDNN--IVTSSGDTTCALWDIETGQQ-----KTVFVGHTGDCMSLAVSPDF-NLFISGACDASAKLWDVREGTCRQT-------------FTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHE----SIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSG-HDNRVSCLGVTADGMAVATGSWDSFLKIWN........................................................................................... 340
29 -58.600[R] KOG0645 WD40 repeat protein  ali follow..  13  1.................................................................................................................................................................................................................................................................................SGHTGRLWSVAAHPMLPLFATSSQDKSVRIYNSNTYNLVHVIDGFHTRSIRRVAWRPI-ERPVLAVASFDSVVSINEKIDDD--ECTAALEGHENEVKCIAWSCNG-NYLATCSRDKSVWIWEATEDDEFD--CLAVLQEHTQDVKVVTWHPTED-LLVSGSYDNSICFWRDDGDD------------ALTCQLQGHTNTVWALAFSPNGNTLASADNDGNVFLWIKISSNEDVATIDSTN-HIHKGAVYTISWMNDAT-LCSAGGDGKIVVYQREKHDAYEQDHAHGVYEINSLEYLRDD-RLLSGGDDGECRVWS........................................................................................... 320
30 -57.600[R] KOG0322 G-protein beta subunit-like protein GNB1L, contains WD repeats  ali follow..  12  9.............................................................................................................................................................................................................................................................................VFSLRSPDGAVNSLCFQESDR-LLAGTIKGSVFLWDLQTNRSALHF-EVGSDPITSLHHTPDR----LVTQEKGGTITMFSIGGSSYVKERSHLGFCRSALHTNTSKTNE-QLLFYPCEESSIGVLHVTDAAAPTQILVPDDPQLPKLGSVTCFKCASQLFLLAGYESGHFLTWDISS--------------SVILDVMELAQDATSVDYDPVTNRGIVGGPTDKLISFSYQRSSMQMQLGSE--LCIKNPGVNGVRIRPDQKVFASAGWDGRIRIFSWKSLRPLAVLTQHKNGGVMDLAFSSQAPIMAAAGMDGQISLWD........................................................................................... 320
31 -57.600[A] KOG0291 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  184..............................................................................................................NLSGHTDAIVACFFEANSLHLNTISRNGQLCLWECSLAPSDLEDAERPKIAPPQRKKEKKAVSDNESEDDVENVVEKDALKEESTKEAEDVNHIKNEDETKSHPFFYKKITRHYLADEPRKEQRDVQLTAANYNTRTKVLVVAFSSGAFYLYELPDVNMIHSLSISDYPISAALFNCTGDWVALASREGQLLVWEWQSEQYIMKQ-QGHSSEMTCIAYSSD--GQFIATGGEDSKVKLWNTQSS---FCFVTFSEHTSGVTGIQFSRNK-KFLVSSSLDGTVRAFDVNRYRNFRTFT----SPNPAQFSCVAVDYSGELVVAGGQDVFDIFLWSVKTGK-------------LLEIISGHEGPVVSIAFSPTSSTLVSGSWDKTVKIWNCLESNSEHETIDAVSD------VTNVTFSPSGEEIAVATLSGNITIFDIKSAGQVTTIEGRQANYFSTIEYSADGECILAAGKSANICIYHVREAILHSLDGLNDFISRKHLSEFGNMALVEEREEAIRLPGVQRGSSRRFQQEVRVFSVKFSPTGQAFAAAGTEG................ 747
32 -57.500[S] KOG0308 Conserved WD40 repeat-containing protein  ali follow..  13  16.......................................................................................................................................................................................................................................................................ISFIIRDEHEYSNRSAVSALQYDAQNGRLFTGGSDTIIRTWSVPHHKDAFSALEQHTDWVNDMILCGH--GKILISASNDTTVKVWNIERDNKHGFIDCIRTHKDYVSCLAYAPIV-EKAVSASFDHNIFVYDINANFK----TVNNLIGCKDSIYSLATTPNLS-LVLGAGTEKCIRLFDPRTNEKIMK-------------LRGHTDNVRALVVNDDGTRALSAGSDATIRLWDIGQQRCIATCIAHEE------GVWTLQVDSSFTTVYSAGKDKMVVKTPLYDFTKSQLLFK-EEAPVKKLLLSEKDNSLWVGTWKSDIKRWSRPSAQLSIGGDEDGPSTSNANHSVSASSSPPVTFKYIRVKDQKGQQSTPEPGAPAIKKHAMLSDKRHVLTRDSDGNVALYD.......... 419
33 -57.000[R] KOG1188 WD40 repeat protein  ali follow..  13  27...................................................................................................................................................................................................................................................................................LGIDTSKTVQAGKENLVAVLCSNGSIRIYDKERLNVLREF-SGYPGLLNGVRFANS--CDSVYSACTDGTVKCWDARVAREKPVQLFKGYPSNIFISFDINCNDHIICAGTDDDALLVFWDARMNSQTKDSLGAYSETHSDDVTQVRFHPSNPNMVVSGSSDGLVNVFDINIDNEEDAL----------VTTCNSISSVSCIGWSGKGYKIYCMTHDEGFYWWDLNHLDTDEPVTRLN-KEDALDYLIGGLYHEKTDHVIGGTNKGRIHLMNCSMSGLVTSLQGGHAATVRSFCWNVQDDSLLTGGEDAQLLLWKPAIEKTFTKKESMKIASSVHQRVRVHSNDSYKRRKKQ...................................................... 387
34 -56.900[A] KOG0306 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  13  59....................................................................................................................................................................................................................................LILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRL-KGHKDAITQALFLRE--KNLLVTSGKDTMVKWWDLDTQ---HCFKTMVGHRTEVWGLVLLSEE-KRLITGASDSELRVWDIAYLQEIEDKAGSIMREGRDRVVNLAVDKTG-RILACHGTDSVLELFCILSKKEIQKLPTPQPVRTSRITIGGHRSDVRTLSFSSDNRQVVIGTKTGKLQLYDLASGNLLETIDAHDG-LQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYG-HKLPVICMDISHDGALIATGSADRNVKIWGLDGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTRE...... 707
35 -56.700[D] KOG1036 Mitotic spindle checkpoint protein BUB3, WD repeat superfamily  ali follow..  15  1....................................................................................................................................................................................................................................................................MTTVTPSAGRELSNPPSDGISNLRFSNNSDHLLVSSWDKRVRLYDVSTNSLKGEF--LHGGAVLDCCFHDDFS---GFSVGADYKVRRIVFNVGK----EDILGTHDKAVRCVEYFDFVTGQVITGSWDKTVKCWDPRGASGPERTQV---GTYLQPERVYSMSLVGH-RLVVATAGRHVNIYDLRNMSQ-----------PEQRRESSLKYQTRCVRCYPNGTGYALSSVEGRVAMEFFDLSEAAQAKRKSEAGRDIVYPVNSIAFHPIYGTFATGGCDGFVNIWDGNNKKRLYQYSK-YPTSISALSFSRDGQLLAVASSYEAIFVRSNEIEVKPKPKVYPNPAA.......................................................................... 354
36 -56.700[A] KOG0319 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  24.............................RWSANGQKLFSTCTNVVKVIDLADNTASYTIGDPEDELRITCTAVDKNRNRLLVAYNNQIIREYSIPLDPSTTKPELARTWKTIHTAPILVMEFNEEGHLLATGSADHIVKVWNLTEQQCTHTLKGPSVVSAILFGHEKLVVGYIEGQLNLYNIMRGAPKKLVNTWKSHNS--VPDSRVVVALSRDQTMSIHETETQETLRVLPLYESIEGGAIGHN-GNLFTVGEEGVVKEFVIETAKLVRKKRIASSNLDHLAYDVVSNRFLAISAEQNLIILDFENLKIARQIVGFHDEIYSCCLLGKD--ESHMAVASNTSEIRLYNTKTLD---CQLIRGHTESVLSVVSPTWDT-SLLASCSKDNSIIFWRLVTSSCSTLVPVAAATGHANTVTALAISNTGRAFLASVSTDCTIKLWGLGVSTKLKEVKIDAEKDTCSSTMVAHGKDVNCVDISESDALIATGGMDKLVKLWQVDTHKQLGIAGTLSGHRRG---VGDVKFAKNSHKLASCSGDMTIKIWNISEKSCLQTISG-HSCAVFRVIFARNDSQLISADSAGIIKIWTKTADCECSIDAHTDKIWSLSKNHNESEFVTAGTDGRIVVWKDVTEEKQKAEDNKRREAIEQDQTLTNLLSQKRYSEA.............. 671
37 -56.700[Z] KOG0318 WD40 repeat stress protein/actin interacting protein  ali follow..  92..............................................................................................................................................................................DTVNKEHLLKNEFQPIAGPIKDISWSPDNQRIVAVGEGRERFGHVFMSETGTSVGEISGQSKSINSADFRPARPRIVTGSEDNTIAVFEGPPFKFKMTKQDHSRFVQAVRYSPDGKFFASAGFDGKVFLYDGTSSELVGEFGPAHKGGVYALAWKPD--STQLLTCSGDKTCRLWTVESRELVSEF--VMGTTVDDQQVSCLWQGDN-LITVSLSGVITYLNVADPSK----PLRVVKGHNKPITVLGLSDDRS-TIYTGSHDGVVTNWNSGSGTN--------------DRITGTGHGNQINGIAAWGDFVYTCGIDDSLRQFSVEGNSYTDYVVKLNCQLPIKYEASSIAVNADTSDVAVGGDDQKLHIYTLKGGVLEPKVELDHLGAVTDVSYSPDLKYLVACDAHRKVVLYSVEEYKNKEWGFHSARVNTVAWSPNSLLVASGSLDTTIIIWSVANPTIIKNAHPQSQITRLVWLDNNTVISTGQDCNTKVWHVEN....... 607
38 -56.600[B] KOG0639 Transducin-like enhancer of split protein (contains WD40 repeats)  ali follow..  70..GLNIEM-QTEIAKRLVAQAVERAKQVTMAELNAIIGQQQLQAQHLSHGHGPPVPLTPHPSGLQPPGIPPLGGSAGLLALSSALSGQSHLAIKDDKKHHDAEHHRDREPGTSNSLLVPDSLRGTDKRRNGPEFSNDIKKRKVDDKDSSHYDSDGDKSDDNLVVDVSNEDPSSPRASPAHSPRENGIDKNRLLKKDASSSPASTASSASSTSLKSKEMSLHEKASTPQAAAGLRTPLAVPGPYPAPFGMVPHAGMNGELTSPGAAYASLHNMSPQMSAAAAAAAVVAYGRSPMVGFDPPPHMRVPTIPPNLAG---IPGGKPAYSFHVTAD--GQMQPVPFPPDALIGPGIPRHA---RQINTLNHGEVVCAVTISNPTRHVY--TGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKLLPDG-CTLIVGGEASTLSIWDLAAPT-----------PRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTD-------ASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQH--DFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYE.......... 767
39 -56.600[B] KOG0273 Beta-transducin family (WD-40 repeat) protein  ali follow..  10  2..............................................................SITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPSASILQKGLQYVEAEISINKDGTVFDSRPIESLSLIVAVIPDVVQMRQQAFGEKLTQQQASAAATEASAMAKAATMTPAAISQQNPPKNREATVNGEENGAHEINNHSKPMEIDGDVEIPPNKA---------------------------------------TVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQVPSNKDVTSLDWNSD--GTLLAMGSYDGFARIWTENG----NLASTLGQHKGPIFALKWNKKG-NYVLSAGVDKTTIIWDAHTGE-----AKQQFPFHSAPALDVDWQNNMT--FASCSTDMCIHVCRLGCDH-------------PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKE------IYTIKWSPTGPMLASASFDSTVRLWDVEQGVCTHTLMK-HQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQGTGGIFEVCWNARGDKVGASASDGSVCVLDL................................................. 522
40 -56.500[K] KOG0263 Transcription initiation factor TFIID, subunit TAF5 (also component of histone acetyltransferase SAGA)  ali follow..  10  1...MSATN-QPQDLNRIVLDYLAKKGYSRTE------AMLRLEASGSGVSVEEKLKSIEETPDAYTHTYTILRDWVDSSELYKAELHRILFP----SQDHYEAAKQFYELFKDDHTDLHDFDVKNLKSLSLPSHVAEDRTAQQYRQNKYQLHFSRITFDLLLHFLFENVSNGGSNQHIDIHIVPGRPTVLENAKVINEQEGITGQSFERGDAQLQPVKLQQMPMDKEMEKIVEMDLEEEDMMHQNDPNNQSPKLLKEFRKLHEPNAEDAPSRDYIPLPPHKGVDILSEVEAVKDWSKRLHLGPRASLPSVCMYTF-HHTNNNMNCAEFSPD--STMIACGFQESYIRLWSIKADKDSDGSVRLLSHSGPVYGTTFSPDN-KYLLSCSEDASARLWSVDTKTA-----LVAYKGHTGPVWDVAFGPFG-HYFATASHDQTAQLWSCDHIY-------------PLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCRLWDVHRGHSVRVFNGHTQ-------VTAVAIAPDGHTMASADSEGLIHLWDIGTGRRIKTMRG-HRGNIYSLSFSRESTVLVSGGSDCTVRAWDVKTNYNNPVSSSLTGSVVTPFSAKTSTFNEVNWSTS------PDQMVALYTKQTPIFNVSFTRRNLCLAISVS.................. 643
41 -56.400[A] KOG0285 Pleiotropic regulator 1  ali follow..  13  86..........................................................................................................................................................................................................PKGSKELRKSATEKALVVGPTLPPRDLNNTGNPGKSTAILPAPGSFSERNLSTSRWPRPEWHAPWKNYRVLQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTL-TGHIGQVRGLAVSNR--HTYMFSAGDDKQVKCWDLEQN---KVIRSYHGHLHGVYCLALHPTL-DVVLTGGRDSVCRVWDIRTKMQIFVL------PHDSDVFSVLARPTDP-QVITGSHDSTIKFWDLRYGKS-------------MATITNHKKTVRAMALHPKENDFVSASADNIKKFSLPKGEFCHNMLSLQRD------IINAVAVNEDGV-MVTGGDKGGLWFWDWKSGHNFQRAETESEAGIYAACYDQTGSRLVTCEGDKTIKMWKED-------EDATPETHPLNFKPPKEIRR.............................................................. 476
42 -56.300[U] KOG0277 Peroxisomal targeting signal type 2 receptor  ali follow..  14  3.......................................................................................................................................................................................................................................................................AVCGGAARMLRTPGRHGYAAEFSPLPGRLACATAQGTLLILDPDEAGLRLFRSFDWNDGLFDVTWSEN-NEHVLITCSGDGSLQLWDTAKAA--GPLQVYKEHAQEVYSVDWSQTRGELVVSGSWDQTVKLWDPTVGKS-----LCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAG-------------VRIVIPAHQAEILSCDWCKNENLLVTGAVDCSLRGWDLRNVRQP--VFELLGHTYA---IRRVKFSPHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPQVADCSWDETIKIYDPACLT...................................................................................... 320
43 -56.200[S] KOG0321 WD40 repeat-containing protein L2DTL  ali follow..  13  120.............................................................................................................................................................................................................................................................................SECLMMLNQLPFCLGFANNESLLAVCTETGALELFDSRFYDRRIHGWLAHNNAIFSVNFSKD--DSLLATSSGDQTSKVFDLSTQQCITRLGVDGYHSHSVKQVNFCNDSPYNLVSCSRDGSIIFWDMRTHGITRIRKAHENSGRDCSITSATWLPQSTSVISSCSANSALKLWDLRTVHTVRPLPAAT---TPELTTSKRDFGVTNVCTSPDGERIYAASRDSIIYEYSSRHLNSGFCKTYKDPRLRISSFYVKLACSPDGATLACGGKTSGVVVFDTTRNSSSAMLTGGHTKDVTAVDWSSEGQ-LASISDDGSVRVWNSSLHGSNLREKNFSEIFYWGFSEK................................................................... 490
44 -56.000[R] KOG1273 WD40 repeat protein  ali follow..  13  18...............................................................................................................................................................................................................................................................................EEYLEHGVIKCVAFNHRGSLLAAGCADGGCVIWDFETRGIAKEIRNDCSAAITSVSWSKY--GHRLLVSAADKSLTLWDVSTGEKIARTI----LQQTPLQARLNPGSPSLCLACPLSSAPMIVDFDIDCTTPQRSKCPESNPPFSPAAACFNKCG-DLVYIGNSKGEILIVDYKSVRVLAL------------VSASGAAPVKNIVFSRNGQYLLTNSHDRTIRIYENLLPAKLTLFREFQDSVT-KMHWKAPCFSGDGEWVVGGSGEHKIYIWDR-AGHLVKILEG-PKEALIDLAWHPVHPIIVSVSLAGLVYIWAKYTENWSAFAPDFKELENEEYVEREDEFDLIPETEKVKVLDVNEDVDIDTVEKDAFSDSDMSVEELRYLPAEPIPDTNDQQDN........ 432
45 -55.900[S] KOG0295 WD40 repeat-containing protein  ali follow..  11  2......................................................................................................................................................................................................................SLSERQKEEINRAIAEYMQNNGYSESFSVFLKESSLSENDIKPLGGILEKKWTTVLRLQRKVNDLESKLQESQREINHGAPTRDKRQAADWIPRPPETQKL-TGHRLPITRVIFHPL--WTIMASCSEDATIKVWDYETGQ---LERTLKGHTDAVNDIAIDAAG-KQLVSCSSDLSIKLWDFGQTYD----CLKSLKGHEHTVSSVTFLPTGD-FVLSASRDHTIKQWDISTGYC-------------VYTFRGHNDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLRDHEHAVECTNVTGQQPEGNSTHILFSGSRDRSIKAWNINTGDVLFTLLA-HENWVRGLAFHPKGKYLISVADDKTLRVWESAQRCMKAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVWECR................................................ 404
46 -55.600[BK] KOG1063 RNA polymerase II elongator complex, subunit ELP2, WD repeat superfamily  ali follow..  10  31..GLVSFGAQNAVAVQILTTLPGHKASVNCTHPTSKFAFKAKKLDRQYLLSGDSDGIIILWELSTLNNDQQWRHVLQLPLSHKKGVTCITAYMVSETDAMFASASSDGVDVSFPSQPSEECKVVCLDSICVDTKAIVTLSLAELPQNPGRFALALGGLDNKIKLYSGERTGK-----TSVCELKGHTDWIRSLDFSLPLHTTEEIPNSIMLVSSSQDKVIR---KLVLVGDVGSWRREITLASYIEGPVFVSGTFTY--------QISVESVLIGHEDWVYSVEWQPPVISILSASMDKTMMIWRPEKKTVCVGELSHCALGFYGGHWSPN--SLSILAHGYGGAFHLWRNVSSSKEQMQKVPSGHFAAVTDVTWARTG-EYLLSVSQDQTTRVFSAWKNDEGHELARPQVHGHDINCVAMVQGKGN-HRFVSGAEEKVVRVFEAPLSFLKTLNHTCAGGEPESHKLYGHGNELFSLCSDHKGNLVASSCKAQSIWLWEVGTWKAVGRLQSHSL------TVTHLEFSYDDTLLLSVSRDRHFSVFSIQRTDKLMAKVEAHKRIIWACSWNPFGHQFATSSRDKTVKIWSVENKQILVLPPFGSSVTAVAWTGLDRNVAVGMESGLIELSNVKLRLEPFMCHVSAVNRLAWRPTEKCLTSCGDDNCVR............. 834
47 -55.400[R] KOG4497 Uncharacterized conserved protein WDR8, contains WD repeats  ali follow..  12  1.............................................................................................................................................................................................................................................................................MNFSEVFKLSSLLCKFSPDGKYLASCVQY-RLVVRDVNTLQILQLY--TCLDQIQHIEWSADSL-FILCAMYKRGLVQVWSLEQPE----HCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCTKS------VSYIKYPKACLQGITFTRDGRYMALAERRDDYVSIFVCSDWQLLRH-------------FDTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLG---IKSVAWSPSSQFLAVGSYDGKVRILNHVTWKMITEFRANPKMGIGMLAFSPDSYFLATRNDNNAVWVWDIQKLRLFAVLEQLSPVRAFQWDPQQPRLAICTGGSRLYLWSPAGCVQVPGEGDFAVLSLCWHLSGDSMALLSKDH................ 437
48 -54.900[S] KOG2106 Uncharacterized conserved protein, contains HELP and WD40 domains  ali follow..  11  166.............................................................................................................................................................................................................................................................................QRHYAGHNDDVKCLAVHPDRITIATGQVAGTVRIWDSVTLNTLHVIGGFFDRAVTCIAFSKSNGGTNLCAVDNDHVLSVWDWQKE---EKLADVKCSNEAVFAADFHPTDTNIIVTCG-EITSLLLDTRRKLPLIRSKDYSRTRKAKVVLCVTFSENGD--TITGDSSGNILVWGKGTNRISYA------------VQGAHEGGISPLCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTEIPEQFTQGHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGHRPVWDK--IIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQ.... 608
49 -54.800[D] KOG0267 Microtubule severing protein katanin p80 subunit B (contains WD40 repeats)  ali follow..  17  2...............................................................................................................................................................................................................................................................................SLCGHTSPVDSVAFNSEEVLVLAGASSGVIKLWDLEESKMVRAF-TGHRSNCSAVEFHPF--GEFLASGSSDTNLRVWDTRKKG---CIQTYKGHTRGISTIEFSPDG-RWVVSGGLDNVVKVWDLTAGK-----LLHEFKCHEGPIRSLDFHPLE-FLLATGSADRTVKFWDLETFELIGT-------------TRPEATGVRAIAFHPDGQTLFCGLDDG-LKVYSWEPVICRDGVDMGWSTLG-------DFCINEGKFIGCSYYRNSVGIWVSDISELEPY-EDKNECMVKRFSVLNDQSERMGSGPRGSVSP-----------DYETREIKNIYVDSTGGNLNVAQNPGSLKATLPLESGKVATMVSEKQNAAYFGPAGDKYSSTSRDSDSGEESSYSERE.... 365
50 -54.700[I] KOG0301 Phospholipase A2-activating protein (contains WD40 repeats)  ali follow..  10  3..........................................................................................................................................................................................................................................................DDGLGDVPMETESMPQYTISHVIEAHKSDTKALAVTQGGC-LISGGRDETVKFWAKKGKQKTHAFEQPKGITVNSIAYAELADGWRLFVGRRDGTIAVFGPSQAE---PYAIFNEHKQNVCCLHINEKA-THMLSGSWDSNVIIWPITELNSSS-FTTIVCPGHTLSVWALASFPDLPNTYLSASADKTIRMWFGDT---------------TLSVFKGHTDVVRALVVLSSSH-FLSAGNDGHIIHWDVASASILRKFATQAHEF-------IYSMTLSDSHILTTGEDGTLEFWAIDGGKDGNLVIQLPTTNTWDAKVLLNSD-IAVAGSDGRIYIMTTDKNRDDILDAFDAEVVAKLTAKTERMKQEEHETVTIKVDIDDLNLKYKKGTDPGLCAQEFLSENNLPIHYLEEITR.............. 404
51 -54.300[S] KOG0772 Uncharacterized conserved protein, contains WD40 repeat  ali follow..  12  4......................................................................................................................................................................NTAPKKNSEKKARVFDLQAMFAQTISNAPRTEEPTHVPQSVSVSSKSESGVSSSAVSLPPGFQMQQSEAGPSSSRAEGPEDSDDSDFDETEAISIIKLIPAACEAKISHGTQAISALRVEPPGVRFASGGLDYYVKLFDFQKMDMSKELLPAESHVINSLAFSPN--GETLVVASGEAIIRLLDRAGKQWSETVRITKGHTATVNCVEFNPLNKNEFISCSDDGSLRLWNLDDHKHRKVIKTKGANGKRVSPQVCTFSPDG-KWIAAGCDDGSVQAWKYGS----------QYVNVNYLVRKAHNGSITSIAFSPDSKRLLSRGFDDTLKMWSLDNPKEPLLVKTGLENAFK---STDCGFSPRAEVVFTGTTPGTLQFFDPMTFDLVYKIDY-PGISCHRIQWHPRLNQIIAGLSDGTIHVYDQTMSQRGVMSCVTKPLKRNRFQPRGEEGEEKEVTGWRIKKYLRMQLRPEFRKPADMPINGKSANGRVAASGGSLHSYLAKQ.......... 549
52 -54.200[T] KOG0279 G protein beta subunit-like protein  ali follow..  13  1......................................................................................................................................................................................................................................................................MAEGLVLKGTMCAHTDMVTAIATPVDNDVIVTSSRDKSIILWKLTKEDKAQRRMTGHSHFVQDVVLSSD--GQFALSGSWDGELRLWDLATG---ESTRRFVGHTKDVLSVAFSTDN-RQIVSASRDRTIKLWNTLGECK---YTISEADGHKEWVSCVRFSPNTLVTIVSASWDKTVKVWNLQNCKLRNT-------------LAGHSGYLNTVAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLEAGS-------IIHSLCFSPNRYWLCAAT-ENSIRIWDLESKSVVEDLKVDKVIYCTSLNWSADGNTLFSGYTDGVIRVWGIGR........................................................................................ 325
53 -54.100[R] KOG1539 WD repeat protein  ali follow..  12  126......................................................................................................................................................................................................................AFKGIEEHLAPIGNLQLTGKFTPTSIVHPDTYLNKVLVGSQEGPLQLWNINTKKMLYQFKGWGSSVTSCVSSPALDVVAIGCADGKIHVHNIKLDEEIVTFEHASRGAVTALSFSTDGR-PLLASGGSFGVISIWNLNKKRLQSVIR--DAHDSSIISLNFLANEP-VLMSASADNSLKMWIFDTNDGDP-RLLRFRSGHSAPPLCIRFYSNG-RHILSAGQDRAFRLFSVIQEQQSRELSQRHISRRAKVSRNHLLLAILACAISACGNFAVVGTAGGWIERFNLQSGISRGSYFDMSEKRAHDGEVIGVACDSTNTLMISAGYHGDLKVWDFKKRELKSQW--DVGCSLVKIVYHRVNGLLATVADDFVIRLYDVTLKMVREFRGHTDRITDLCFSEDGKWVISSSMDGSLRIWDVLAKQIDGVHVDVPITALSLSPNMDVLATAHSDQN............... 642
54 -53.800[R] KOG0315 G-protein beta subunit-like protein (contains WD40 repeats)  ali follow..  16  3.............................................................................................................................................................................................................................................................................................DQQQLILATGGYDHTIKVWQAHTGNCIKTMRFVETSQVNALDRTPDKT---RLAACGYQCIRLYDLESNCT-APVINFDGVQKNVTRLGFQEDG-NWMFTAGEDHHVRIWDMIAAPP----HCSRIFDCEAPVNAACLHPNQV-EIAMGSQNGSVFLWDVKSER-------------HERIVPEVDASIQDVAISPDGRYLAAANNKGNCYIWSLTSQDQMSTLRPNRKIPAHSRYILRCKFSPDSRLLLTTSGDGTVCIWKTDDFSKWRELCI-ENYWVWDAAFSADSKWLFTASSDGIARLWKQTKSSIRDYTGHTKAITALSFKDEIPVKSTNISDVQSSAKPPT----QRDNPPGTNNLAFFETVGRVAMNPYMGNTTTELN.......... 362
55 -53.800[J] KOG0650 WD40 repeat nucleolar protein Bop1, involved in ribosome biogenesis  ali follow..  1.................MTKKLALKRRGKDSEPTNEVVASSEASENEEEEEDLLQAVKDPGEDSTDDEGIDQEYHSDSSEELQFESDEEGNYLGRKQSSSAEEDEESSDEEDNEEEESTDGEEVEDEEKDSKSKQTDDKPSGSGAASKKALTAELPKRDSSKPEYQDSDTSDEEDIRNTVDEYKHIGYDWDAKKIIKPPQGDQIDEFLRKIEDPDFWRTVKDPLTGQDVRLTDEDIALIKRIVSGRIPNKDH-KRSFLPSVSEKKRVSYSRYLRERFLRCLDLYLCPRAKRVKLNIDAEYLIPKLPSPRDVESMVYRGHTDLVRSVSVEPK--GEYLVSGSDDKTVKIWEIATGRCIRTI----ETDEVVRCVAWCPNPKLSIIAVATGNRLLLVNPKVGDK------VLVKKTDDLLAEAPSQDVIE-SERIKTAVQWSNAEADEQEK-------------GVRVVITHFKPIRQVTWHGRGDYLATVMPEGANRSALIHQLSKRRSQIPFSKSKGL---IQFVLFHPVKPCFFVAT-QHNIRIYDLVKQELVKKLLT-NSKWISGMSIHPKGDNLLVSTYDKKMLWFDLSTKPYQTMRLHRNAVRSVAFHLRYPLFASGSDDQAVIVSHGMVYLKKLQTHEFGVLDVNWHPVQPWVFSTGADSTIR............. 781
56 -53.600[A] KOG0640 mRNA cleavage stimulating factor complex; subunit 1  ali follow..  17  99.............................................................................................................................................................................................................................................................................TAYVTSHKQACRAGAFSCDGSLVATGSVDASIKILDVERGHPVIRTLYDHTDEVSYLEFHPK--EHILASASRDGTVKLFDIAKPSVKK-AHKVFTDCEPVLCLSFHPTG-DYVAIGTEHNVLRVYDVATTQC--FVSAIPSQQHKAGVTCVKYSPTG-KLYATGSYDGDIKIWDGISGRCINTIA------------AHGGAAICSLEFTRNGKYLLSSGMDSLVYLWELCTSRPIQTYTGAGTTGKQEHQTEAVFNHTEDYVLFPDEATTSLCSWNSRNGCRLTLNSLGHNGPVRYITHSPNGPAFLTCSDDFRARFWYRRANN...................................................................................... 423
57 -53.300[R] KOG2444 WD40 repeat protein  ali follow..  4..................................................................................................................................................................................................................................................................................EFDNPPLCMKSNKDGSRLVVGFVDGSIRFYDTQQHEEEFQEKFQTKSSIRGVDLDEH--KKRVYAVTKNRSLCVFDIDTGKRVRCI--LKCHRSVPTAICTLPPKSQQLATADESGEVKTWNLDPEVASENANIRKWQEQDEDINDLKVDVKSN--LLATSSDGTLGAYDLRKAKLKMRS---------------ELMHSELYSVCGTNRSVYVGGEDGYVEVFNLNEYGNL-LERVESGFEMG---VNGIVELRSGLLGLTSQGSNRMRLLNVQPSKRLGYAGYHDDDGIDAITISTDKSVFTMISMSCTIKKWDMGPIIDEIPILRAQDAKSKKMRKTEGFFDGLVGPKNDSDSDDDDEPKSKKRRNDEDSDEEIDEEEQEEDDEEEEEDSD............. 383
58 -53.100[T] COG5170 Serine/threonine protein phosphatase 2A, regulatory subunit  ali follow..  12  26.................................................................................................................................................................................................................................................................................ITEADIISAVEFDHTGDYLATGDKGGRVVLFERNHSKKGCEYSLEIEEKINKIRWCKRTNRAHFLLSTNDKTIKLWKLYEKNLKVVAVYANAHAYHINSISVNSDAE--TYISADDLRINLWNLSISDHSVDIKPENMEELTEVITSAEFHPINCNHLMYSSSKGNIKLLDLRQSALCDNPCKLQEDQDSKSFFSEIISSISDVKFSQNGRYILSR-DYLTLKIWDVNMEK--APVKTIPLHDVLRS-KFECTFSGDDKHVLSGSYSNNFGIYPTDSSLPGDRGQIDYNKKILHASWHPFEDSVAIAATNN-LFVFS........................................................................................... 461
59 -52.600[R] KOG0288 WD40 repeat protein TipD  ali follow..  15  164..................................................................................................................................................................................................................LQKMQDAERLNEANDLYEEMLAKLKANGLETLARQQVDGIVRRNEDGTDHFVSTIPSTCANRIHAHEGGCGSIVFEYNSGTLFTGGQDRAVKMWDTNSGTLIKSL-YGSLGNILDMAVTHD--NKSVIAATSSNNLFVWDVSSG---RVRHTLTGHTDKVCAVDVSKFSSRHVVSAAYDRTIKLWDLHKGYCTNTV------LFTSNCNAICLSIDG-LTVFSGHMDGNLRLWDIQTGKLLSE-------------VAGHSSAVTSVSLSRNGNRILTSGRDNVHNVFDTRTLEICGTLRASGNRLASN--WSRSCISPDDDYVAAGSADGSVHVWSLSKGNIVSILKE-QTSPILCCSWSGIGKPLASADKNGYVCTWT........................................................................................... 515
60 -52.600[A] KOG1272 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  11  3..................................................................................................................................................................................................................................................ISSEDNNLMEKVLPPVEQVLTWTLIQICMQESDVELETKVKKYLRGEGANLETLKDKKLKTQLASREKLYGKS-AKAAAKIEKWLLPAE--AGYLETEGLEKTWRVKQTDDILSSRNQYDIVLPDFGPYKLDFTASG-RHMLAGGRKGHLALLDMMNMS------LIKEIQVRETVRDVAFLHND-QFFAAAQKKYAYIYGRDGT----------------ELHCLKERGPVARLRFLKNHFLLASVNMSGQLHYQDVTHGGMVASIRTGKGR------TDVMEVNPYNSVVGLGHSGGTVTMWKPTSQAPLVQMQC-HPGPVSSVAFHPNGHLMATSGKERKIKIWDLRKFEE-VQTIHSFHAKTLSFSQKGLLAAGTGSFVQILSHNYTRYMNHSMVKGYQIEKVMFRPYEDVIGIGHSMGWSS............. 405
61 -52.200[R] KOG0646 WD40 repeat protein  ali follow..  11  2.....................................................................................................................................................................................................................................................EITVIASSSIDEGIGSWDLKTGTEQLQFKPCASPAHGLTAVGESSQLSARNTSGSIFYWSWTKPQA--EVKSYPVEPIKALAANNE--GTYLVGGGISGDIYLWEVATG---KLLKKWHGHYRSVTCLVFSGDD-SLLVSGSQDGSIRVWSLIRRQQGNTLYEHNFNEHTMSVTDIVIDYGGCNVIISSSEDRTCKVWSLSRGKLLKNI--------------IFPSVINALALDPGGCVFYAGARDSKIYIGAINATSEYQVLGSVSEKGKA---ITCLAYCADGNLLISGSEDGVVCVWDPKSLRHVRTLIHAKGSRKGPVNNIQIVRKTIVANSNKTQVSWKSGALIPPPLEKYERPV---EDTMDGIVTVDPPPFSDVPVYSSFLSADLIDEQVKELQQQGSAATEMEMERLKLEYK............... 408
62 -52.100[B] KOG0264 Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1  ali follow..  14  116.............................................................................................................................................................................................................................................................................CEIKINHEGEVNRARYMPQNPIIATKTPSSDVLVFDYTKECNPDLRLRGHQKEGYGLSWNSNLSG-HLLSASDDHTVCLWDINAGPKVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSK--PSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLH------------TFESHKDEIFQVHWSPH-----------------------------------------------NETILASSGTDRRLNVWDLSKIGELLFIHGGHTAKISDFSWNPNEPVICSVSEDNIMQIWQMAEN---IYNDEESDVTTSELEGQGS................................................................. 425
63 -51.700[R] KOG2055 WD40 repeat protein  ali follow..  2..................................................................................................EKDTEELELENAVFGNINNFSSFLDKENETFDVMMNEAPELSEDNDAQEDELEKLEDAEL----MFDTGSADGAKDSVPLDIIAGDNTVKEDEEASNEIPSIWEDSDDERLMISLQDHSRLRKLRQYEDEDMVNGLQYA---ERVYPVPEWAKKQDVTEEEDEFNALSEKSVIPKSLKSLFKSSVSYINQSSKLLAPGTINIKRLKDANF-------QAPSHSGIRCMSIHPY--FPLLLTCGFDRTLRIYQL-DGKVNPLVTSLHLRSSALQTALFHPDG-KRVIAAGRRKYMYIWDLESAQVQKVSRMYGQENFQPSMERFHVDPTGK-YIALEGRSGHINLLHALTGQFATSF--------------KIEGVLSDVLFTSDGSEMLVLSYGAEVWHFNVEQRSVVRRWQVQDGVS-----TTHFCLDPSNKYLAIGSKSGIVNIYDLQTSNADAATLDNITFSINSMSFSQDSQVLAIASKKDTLRLVHVPSFSVPTSATPLGRVTCLAFGKGG-ELCVGNEAGRVGLWKLAHYDLKFVPDKIINWEIRLGKFGYVLLGIQILILHVD............ 552
64 -51.600[T] KOG1354 Serine/threonine protein phosphatase 2A, regulatory subunit  ali follow..  12  23...............................................................................................................................................................................................................................................................................DDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISEREASPRRIFANAHTYHINSISINSDYETYL--SADDLRINLWHLEITDRSVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTR-DYLSVKIWDLNMEN--RPVETYQVHEYLRSKKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASDFNKKILHTAWHPKENIIAVATTNN-LYIFQDKVN....................................................................................... 447
65 -51.600[R] KOG1524 WD40 repeat-containing protein CHE-2  ali follow..  10  1.......................................................................................................................................................................................................................................................................MKLKLSASRKTRHTEMVCGVGWIGTEA-ILSAADDHVFLLTNTATNESQQILNMPETFFPTSLHIFPRSQNDVFAVSTSDGKINILS----RNGKVENMVDAHNGAALCARWNSDG-TGLLSSGEDGFVKMWSRSGM------LRSVLAQFATAVYCVAWDSTSSN-VLYCNADHCYIKSLKMQ--------------VAPIKWKAHDGIILCCDWNPTSDLIVTGGEDLKFKVWDGFGQILFNS-------SVHDYPITSISWNTDGTLFAVGSHN-ILRLCDKSGWSH--SLEKMNAGSVMALSWSPDGTQLAVGTAAGLVFHAHIIDKRLNTPTMIEYNERTVNIIVQCEKIFLVSDGMTITIFTYEGRKLIQVMALLDERKIDLANDTLVVRDRADNKVLHFFDPTTG...... 447
66 -50.900[U] KOG0771 Prolactin regulatory element-binding protein/Protein transport protein SEC12p  ali follow..  1......................................................................................................................................................................................................................................................................MASNQQPPSNLQTYGVPIYAVDWILEEAVRSKITKDQDDDDDDGSSSSSYIVLSGGGGEGRSGIP-----NVILICRVDLHTNSL--------SEQPIGRRVIGTDLPYRMAIHPRQGGLICALPNSCRLFDWEIEDDNEEESEKVVKELKDVGQQLSLSFNQDGT-VLATGAEDGTLRVFEWPSMKTLLN-------------ESKTHASVKSLTFSESGKFLVSL-GAPLCRVWDVNASAAIASLSK-----EKDEMFASCRFSVDNSVAANTQRGGSIITWDTTSWRRRSSKLIKRNNSISAFNVSADGKLLAVGTLEGDVLIIDSTKMQTIVKKAHLGLVTALTFSPDSRCLVSVSFDSRARLTVIKQKGEKRRWVAALLFVLVYVVLYYLMVAMGII................. 382
67 -50.800[A] KOG0284 Polyadenylation factor I complex, subunit PFS2  ali follow..  12  17................................................................................................................................................................TIQPSTSSMQNSQPRIMNNHHHPHNRFQREHVMPDVMGDGPGRRLRKNVANVRRHVDYVSTVLNHCENRLWQYGKQRILQQPDILYQQYAVPADSTPDVPVDCILTKFIRTAMNKVKCPVYSVCWSPEGKRLITGCQTGEFTLWNGTAFNFETIL-QAHDSAIRALKWASN--EQWLLSADQGGYVKYWQPNMNN---AHMFSAHKDEAIRGLAFAPTD-VKFATASDDGTARVWDFARYTE-----ERVLRGHGAEVRCIDWHPTK-GLIATGSRDTPVKIWDPKSGSC-------------LATLQEHKSSVMAVEFNKNGNWLLTGGRDHLVKMYDIRMMKEMRTYRAHKKE------VISLAWHPIHELFVSGGGDGSIVYWMVDGEKEIGLLEHAHDQAIWSMKWHPLGHILATGSNDNNTKFWARFGLSNTNMIGHLDKEREPRMAPPKPSIETQETYRPDTFIPGEHLYEQLNRDHNMMTTDSTLLVPDDLTRQNFAPMIGAKRTLIKQPPAKK 522
68 -50.400[R] KOG2096 WD40 repeat protein  ali follow..  10  2.........................................................................................................................................................................................................................................................................................DSVLVVGIASVILGALIAVLFFGSYFRKRTSEV-QSMAKAEPQDPIRNPK--SNHPAPKKNHPKSQASDKNQNKRHHDLNTLKGHGDAVTGLCFSSDG-KSLATACADGVIRVFKLDDASSLKFRFLRINLPAGGHPTAVAFADDASSIVVACHHMSGSSLYMYGEDKQKDQQGKLPLPSHEKRSVLTISGATATYGTADGSVVIASCSEGTDIVLWHGKTGRNLGHVDTNQLK------NHMAAVSPNGRFLAAAAFTADVKVWEIVYQKRVMQLKG-HKSAVTWLCFSPNSEQIITASKDGSIRVWNINVRPLCDSGGNPLHYDRLSLCPEGKILAASH-GSTLQWLCAETG-TAEKAHEGDITCISWAPKAITLGTSGDDKKVKLWEAPKS...... 451
69 -50.400[S] KOG0283 WD40 repeat-containing protein  ali follow..  92...MAAPGSISERRRRLLHGMGLASNKDMVSAVSIRRVVSNAPVVSNGEEKKMKKKMNHEVDEQDHDHVPVMLARSRSESDSKQRLTRTYSTICPTRTRICQYQTPIRQTPAVCGNGKALRGGGEALTSVMSNARVGAFFLIKNLDTGKEFIVNEYDEDGMWNRLSDLQTGKQLTLEEFEKCVGYSPVVKELMRRENVNRINYEPLMDLRKFNSYLSKNIKGVAHSMSLRVADKDVSDGSTDSPKKGKDHKHGKANEWVKVR-LSALHMCQEIQAHEGAVWTIKFSQDAHYLASGGADRVIHVWEVQECELMSMNEKGHLDAILDLSWSKSQ---LLLSSSMDKTVRLWDIETKT----CLKLFAHNDYVTCIQFSPVDENYFLSGSLDAKIRIWSIQDRH------VVEWSDLHEMVTAACYTPDG-QGALIGSHKGICRAYDTEDCKLSQTNQI----DVQSNKKSQAKRKITSFQFSPVNPEVLVTSADSRIRILDGSEVIHKFKGFRNTCS------QLSASYSQDGKYIICASEDSQVYLWKNDFHRTRSTLTTQSHEHHGHVRGEPPPVQIHSKRHSKRISTSSPSSTISSPTKEETSATGPTTSNRNKKSGLPPMPKKAATKSQILSSWSWFDSGGHGPQTIQPTAWGMVIVTATVHGEIR............. 885
70 -50.000[DO] KOG0305 Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits  ali follow..  10  2................................................................................................................................................................................................DSGMRATCTVPEHFLPRKLSKQNLDRFIPNRSAK---DFDFANYALTQGSKRNLDEVTSASRKAYMTQLAVVMNQNRTRILAFRNKPKSLLSTNHSDSPHQNPKPVKPRRYIPQNSERVLDAPGLRDDFSLNLLDWGSAN----VLAIALGDTVYLWDASSGST-SELVTIDEDKGPVTSINWTQDG-LDLAVGLDNSEVQLWDCVSNRQVRTL------RGGHESRVGSLAWDN-HILTTGGMDGKIVNNDVRIRSSIVE------------TYLGHTEEVCGLKWSESGNKQASGGNDNVVHIWDRSLASSKQTRQWLHRFEEHTAAVRALAWCPFQASLLAGVGDGKIKFWNTHTGACLNSVETGSQ--VCSLLWSQSERELLSSFTQNQLTLWKPSMSKMAELNGHTSRVLFMAQSPNGCTVASAAGDENLRLWNVGEPPKTTKKAASKKYPELFSHVNS......................... 442
71 -47.700[R] KOG2919 Guanine nucleotide-binding protein  ali follow..  11  3.....................................................................................................................................NHNVSFSSTMVTSNGDLSLPKLSVTLSAEEILKLRSGRPKNAVESPHAGVPMETSLAAEEEANGDEEEESVRVVDIEDTLELTSNGNEAKPEDQELAIAP--------------------VLQYFQGALVELGRRCWTSSTEAQHYTKGCYWSPDGTCLLVPVHLDGMHVIEMPSDKLQSEVHVPEGGTVYDCVWYPQPETCLWLATRQHEPIHMWDAFDGSLRCSYSGYDDEVMAAISLAFSHDGEQIY--AGYKRCIKIFDTSRPGRF-----CDDYPVKFAISCIAQTTAHPHTLTCGNWHGYIQHFDLRCSHKQGP----------LFTLGGHKGGITQLRYGEFGNGFSGARKCDKILQWDMRNYKQPLVELQRHVDTNQRIQFD---LASDSNWLASGDTRGFVNVWDLKKYGDPSVLPL-HSDCCNGVALNPAMPILATSSGQFHFT--DQSAQGDNVTLNGTETTELPAPADVNQNQKEVLYENAVVMWWCGQT.............................................. 486
72 -47.700[R] KOG2394 WD40 protein DMR-N9  ali follow..  11  122........................................................................................................................................................................................................................................................................SRISGSFAASNSNTSMTNTNFDGKGTYLVNVSDAIFICDLNSQEKDPVKSI-HFSNSNPMCHAFDPDADGHDLLIGLNSGDVYTVSLRQQLQDVSKKSVNNRQDRCTSISWVPGGDGAFVVAHADGNLYNKDGAT--------------------------ESTFPAIRDPTQFSVDKAKYSKSN-------------PVARWHICQGSINSIAFSNDGAHLATVGRDGYLRIFDFLTQKLVCGGKSYYG-------LLCCSWSMDGKYILTGGEDDLVQVWSMEDRKVVAWGEG-HNSWVSGVAFDSNWSSFGSVGQDTQLLLWDPKLSPIIAHRVHTEPLSGLMFTQES--VVTACREGHIKIWTRPSENSSEANPTTALLSTSFTKDNKASLSSKIISGSTFKQ.......... 556
73 -47.400[S] KOG0281 Beta-TrCP (transducin repeats containing)/Slimb proteins  ali follow..  13  106......................................................................................................................................................................................................................DARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKG------LSESRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNQRIQCRSENSKGVYCLQY----DDEKIISGLRDNSIKIWDKTSLE---CLKVLTGHTGSVLCLQY---DERVIVTGSSDSTVRVWDVNTGE-----VLNTLIHHNEAVLHLRFSNGL---MVTCSKDRSIAVWDMASATDITLRR----------VLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKR--------GIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEG-HEELVRCIRFDNK--RIVSGAYDGKIKVWDASTLCLRTLVEHSGRVFRLQF--DEFQIISSSHDDTILIWDFLNVSAQNETRSPSRTYTYIS............................. 507
74 -47.100[E] KOG0280 Uncharacterized conserved protein  ali follow..  12  51...................................................................................................................................................................................................................................................................................LYDTKEDVLSPHDASVLAVAHSTGHVSFYRHQFRAELMFLRGDSSVLMLSLDFSDS--GKELAVSMSNGSVLIIDIDSG---VIKNKWKEHDYEAWTCHYSRQDNNLLYSGGDDAALVCYDQRIPNS---CIWRDIQVHHSGVVSILSRAPFGPYIATGEYGDFMHTLDTRNIGKP-------------LFSANLGGGVWRLEHMETTE---------------------------------------------NYHKVLGILMHRGAQVLRISNDFASKRIFKEHESMCYGGDWRHTDGLLATCSYDKRVCLWED.......................................................................................... 309
75 -46.700[R] KOG2321 WD40 repeat protein  ali follow..  2............................................................................................................................................................................................................................................................................SLKVQNPNNVRVYTVSGEGVTQRLPNWISKRKLKKDYALSHRIELLQDFEYPEASNRIKCTRDGK-YAMATGVYKPHIKVFDFAEMS---LKFERHTDAENVQFEILSDDW-TKSVHLQTDRTVDFHSQGGIHYSTRI--------PKYGRDLKYHYPNCD-LYLAAAGDEVYRLNLEQGR------FLNPLKIESAQIDSPTGGVNVIDINPMHQLLAFGTDAGSVEFWDPRDRSRVGILEIPST-SDNSRSVTALKYRNDGLNVAIGLSDGATLLYDLRSSSPYMSKDQGYSMPIKSLHWMDSALARVLSADSKIIKIWEKDTGKPFSSIEPTVELNDVCPIEGTGLILTANEGSPMHAFYIPSL-RWCSFLDNITEEMEENPDDYKFVTKKELLNLG............. 397

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zhao Y, Hong DH, Pawlyk B, Yue G, Adamian M, Grynberg M, Godzik A., Li T. The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesis. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3965-70. Epub 2003 Mar 21.