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Query: [T] KOG4603 TBP-1 interacting protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSKGRAEAAAGAAGILLRYLQEQNRPYSSQDVFGNLQREHGLGKAVVVKTLEQLAQQGKIKEKMYGKQKIYFADQDQFDMVSDADLQVLDGKIVALTAKVQSLQQSCRYMEAELKELSSALTTPEMQKEIQELKKECAGYRERLKNIKAATNHVTPEEKEQVYRERQKYCKEWRKRKRMATELSDAILEGYPKSKKQFFEEVGIETDEDYNVTLPDPLast
1 -92.400[T] KOG4603 TBP-1 interacting protein  ali  100  1MSKGRAEAAAGAAGILLRYLQEQNRPYSSQDVFGNLQREHGLGKAVVVKTLEQLAQQGKIKEKMYGKQKIYFADQDQFDMVSDADLQVLDGKIVALTAKVQSLQQSCRYMEAELKELSSALTTPEMQKEIQELKKECAGYRERLKNIKAATNHVTPEEKEQVYRERQKYCKEWRKRKRMATELSDAILEGYPKSKKQFFEEVGIETDEDYNVTLPDP 217
2 -21.400[DR] COG5124 Protein predicted to be involved in meiotic recombination  ali follow..  16  1MVT-VKMKSDQKKSILLEIIRGSKSFFKLQEL-ESLGSKKGIVVNTIKEILQQLVDDGLVTAEKVGTSNLYWSFASEGIQKKKLRCKELMEECERMSQDICRKREYIENEKMS----HYTEERNELENKLNALMKIEQDQREELGKFEET----DPIAYDKLVADRKEMADECNRIIDNVFIIQDYICSKFPMEKSEFNSSFGIPPDLD........ 200
3 -21.400[DR] KOG3433 Protein involved in meiotic recombination/predicted coiled-coil protein  ali follow..  16  1MVT-VKMKSDQKKSILLEIIRGSKSFFKLQEL-ESLGSKKGIVVNTIKEILQQLVDDGLVTAEKVGTSNLYWSFASEGIQKKKLRCKELMEECERMSQDICRKREYIENEKMS----HYTEERNELENKLNALMKIEQDQREELGKFEET----DPIAYDKLVADRKEMADECNRIIDNVFIIQDYICSKFPMEKSEFNSSFGIPPDLD........ 200
4 -11.600[K] COG3682 Predicted transcriptional regulator  ali follow..  15  4.........TAAEAHVMEAL--RRSPLSADELVAEVGAAQSWGEATVKTLINRLLKKKAIKSERAEGKHGYRPLVDRSAYVQAESQGLLDR-ISHFAQHRPLKPDEVAKLKKLIDEMGE.................................................................................................. 120
5 -11.100[K] COG1695 Predicted transcriptional regulators  ali follow..  3..........RYAIKALVLLSK--KPRTLYQMSKEISTGVQVSHGTLMPMIRKLLQERYIDFETRGREKVYHLTERGSRFVESKIEEDVKQNLISRNDTSEAIKSAIQILLPAIIAQVEYAFRMLMEGHREEVEGVARDLLRKYGEIDDEQS................................................................. 158
6 -10.900[P] COG0735 Fe2+/Zn2+ uptake regulation proteins  ali follow..  10  2....VTPQLTKNQSLVMGALAHSDGPMSAYTILDKLRDNGFRAPLQVYRALDKLLEYGLVHRLESLNAFVACSCPHEHEHDHGVTAFTICEGCGQVTEFHDEVIEDRLSTLVRAQEFKTEKTTIEI........................................................................................... 123
7 -10.600[K] COG0640 Predicted transcriptional regulators  ali follow..  10  1................................MNEITMQTQADQPKVSSNLAILSEARLVDSIQMGREKIY--------RIAPEKFEDMVDWLDSILHSKSSGGSANYGLSPVNDLNYARTCYDHLAGEMGVYLLEELLKRKWIILDDPEKPRLTTAGAEELTVRGVSLPPRANGKRMFAYGCKD------TVKRFHLGGFLG.............. 160
8 -10.600[K] COG1510 Predicted transcriptional regulators  ali follow..  11  30.........PSTVGRVLGIIYMNRKPMTLSELSEAT----GMSKTRMSQVVREMIDANIAVFEKGVRKDLYDVEQDYYQTFISLFAANWTKVVSKNKVLYKKLNRELSDLLQRDG------LTPEAEEKVNQLLNELKEWLHYYDWLSRLIEFFESEEVFRY....................................................... 174
9 -10.000[K] COG5625 Predicted transcription regulator containing HTH domain  ali follow..  17  20.........KKNEIRIYRLLVEKRRGMRIREIQREL----GISERSVRTHVLNLYRRGLLKREL-WLGYIYTPVSP--LEILQKIKEHLMKSIEELERDLKNQTRS............................................................................................................... 113
10 -9.410[K] COG1777 Predicted transcriptional regulators  ali follow..  13........ENSTRREIIRMLTQFE-RSYALELSRSI----GLSQQAILKQLEMLERANLVTSIGFVPSSVG----------------AKRKLYEPTGFSTLIVDYGRNFLMIQRIPLEND--SERVSVSFDEAISKLESIQHHIEELTKKRTELVKKKDELMAAIKYQLEDEDPITREIVLEYLNTF------DVEEVSRRTALPLEI......... 183
11 -9.400[K] COG2345 Predicted transcriptional regulator  ali follow..  11  1MGDVVKGNDGDTRRKILLILLERA-PVIASDIAEQL----QLSTVGVRRHLDNLVEENLAEAAN-GRPAKTYRLTDKGRSIFGHEYDSLAAAALATLREVGGDDAVRQFARKRIETIVEGITPA--DVTDQSIEDTAKSLVEAFSRHGYAATVDATRNGLQLCQHHCPISTVATEFPELCEQAVSELLGQHTQPLATIAD................. 211
12 -9.360[S] COG2512 Uncharacterized membrane-associated protein/domain  ali follow..  15  247.........SPELCEVLDIIRGHKGRITQKDLRSKL----DYSEVKVSLMLSELEKRGLIRKLRNGRENILVLVDEE............................................................................................................................................ 310
13 -9.230[S] COG3398 Uncharacterized protein conserved in archaea  ali follow..  10  100ITERADVFENSNRARIYEYIKT--RP------LSEIIEKAGIDRGAARYHIKILKAHHKIEAYRESGKTRYFQNNSTYGEEEKKVVSALQNATN--QRIISEIQNGKCNTNLALAR-EIGVSRATISWYVKNLKET--GLIDETRSGRSIIYSINPSYEPLIEK..................................................... 253
14 -9.160[KH] COG1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon  ali follow..  10  2.........KMKTLFLLIKLAKMGAIGKEITVTRELSRELDVSPQTVLRWLEELKEQGYIHKRESRKGTLVELTEKGINLLEKEEISTALYSGFIVGEVISGIGEGAYYVRQYAPLIREYLGFDPYPGTLNVRVLFPKTIFDALCTARPNGRTFGDVRAYRVRIDGIEGAIVIPSRTVHPPKIAEIIAP------VKLRDALNLKDGDKVRIEV... 211
15 -9.070[K] COG5631 Predicted transcription regulator, contains HTH domain (MarR family)  ali follow..  11  73MAAAGLPGLSPIEILILHSIRHRDREKKLADICLALD-----DTHIATYAIRKLEKAGLLTTGKAAKEKTVKITAKGAEACAHANARPSEETLSELAALLRFMSGAFNQATRSAITL.................................................................................................... 199

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Topczewski J, Godzik A., Paszewski A. The Aspergillus nidulans cysA gene encodes a novel type of serine O-acetyltransferase which is homologous to homoserine O-acetyltransferases. Microbiology. 2000 Oct;146 ( Pt 10):2695-703.