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# Query Length Result vs. Range Score %id Covered by template(s)
1 IDP00001 aldehyde-alcohol dehydrogenase BA_4599 [Bacillus anthracis str. Ames] 867 COG1018 18-427 -38.500 15  [E] COG0014 Gamma-glutamyl phosphate reductase
413-864 -101.000 34  [C] KOG3857 Alcohol dehydrogenase, class IV
452-867 -103.000 49  [C] COG1454 Alcohol dehydrogenase, class IV
CSGID 5-867 -237.000 64  IDP00757 alcohol dehydrogenase, iron-containing SACOL0135 [Staphylococcus aureus subsp. aureus COL]
H.sapiens 12-446 -37.900 14  sp|Q02252|MMSA_HUMAN(removed signalp:1-19) Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Homo sapiens GN=ALDH6A1 PE=1 SV=2
93-427 -43.300 13  sp|P54886|P5CS_HUMAN Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens GN=ALDH18A1 PE=1 SV=2
467-866 -84.400 24  sp|Q8IWW8|HOT_HUMAN(removed signalp:1-21) Hydroxyacid-oxoacid transhydrogenase, mitochondrial OS=Homo sapiens GN=ADHFE1 PE=1 SV=1
HGM_OVER 603-703 -2.380 15  PB044863 Q5LB69_BACFN/1-105 PB044863; Pfam-B_44863;
NEW_HUMAN_DOMAINS 145-227 -5.240 18  tr|E7ER46|E7ER46_HUMAN Uncharacterized protein OS=Homo sapiens GN=FAM48A PE=4 SV=1
PDB1018 1-458 -102.000 43  3k9d_A mol:protein length:464 ALDEHYDE DEHYDROGENASE
444-866 -113.000 74  3zdr_A mol:protein length:433 ALCOHOL DEHYDROGENASE DOMAIN OF THE BIFUNCTIONAL ACETALDEHYDE DEHYDROGENASE
PfamA32U 12-438 -35.500 16  PF00171.22; BETB_ECOLI/15-479; Aldehyde dehydrogenase family
467-856 -95.400 28  PF00465.19; Q2SC87_HAHCH/11-388; Iron-containing alcohol dehydrogenase
SCOP207 16-427 -43.400 18  d1o20a_ c.82.1.1 (A:) Gamma-glutamyl phosphate reductase {Thermotoga maritima [TaxId: 2336]}
453-864 -93.400 32  d5br4a1 e.22.1.2 (A:1-383) automated matches {Escherichia coli [TaxId: 562]}
VFDB 18-427 -38.500 15  [E] COG0014 Gamma-glutamyl phosphate reductase
413-864 -101.000 34  [C] KOG3857 Alcohol dehydrogenase, class IV
452-867 -103.000 49  [C] COG1454 Alcohol dehydrogenase, class IV
2 IDP00002 surface layer protein, (pxo1-54) GBAA_pXO1_0079 [Bacillus anthracis str. 'Ames Ancestor'] 404 COG1018 58-218 -5.820 9  [K] COG1802 Transcriptional regulators
CSGID 2-217 -70.400 39  IDP01798 S-layer protein, putative [Bacillus anthracis str. `Ames Ancestor`] GBAA1130 [Bacillus anthracis str. `Ames Ancestor`]
20-404 -62.100 33  IDP02517 S-layer protein, putative [Bacillus anthracis str. `Ames Ancestor`] GBAA2315 [Bacillus anthracis str. `Ames Ancestor`]
23-277 -68.200 37  IDP05609 putative S-layer protein [Bacillus anthracis str. Ames] BA_5054 [Bacillus anthracis str. Ames]
H.sapiens 22-219 -6.520 12  sp|P51790|CLCN3_HUMAN H(+)/Cl(-) exchange transporter 3 OS=Homo sapiens GN=CLCN3 PE=1 SV=2
HGM_OVER 21-206 -2.930 15  PB009233 Q7MX23_PORGI/1-175 PB009233; Pfam-B_9233;
NEW_HUMAN_DOMAINS 89-221 -5.260 9  sp|Q6P1X5|TAF2_HUMAN Transcription initiation factor TFIID subunit 2 OS=Homo sapiens GN=TAF2 PE=1 SV=3
PDB1018 40-223 -62.100 29  6bt4_A mol:protein length:202 S-layer protein sap
46-288 -49.600 25  4aq1_A mol:protein length:892 SBSB PROTEIN
PfamA32U 47-90 -21.000 25  PF00395.20; U5LGG8_9BACI/157-200; S-layer homology domain
47-226 -10.500 10  PF09168.10; Q5FJC6_LACAC/1-156; X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal
SCOP207 84-226 -14.600 8  d1lnsa1 a.40.2.1 (A:1-145) X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain {Lactococcus lactis [TaxId: 1358]}
VFDB 58-218 -5.820 9  [K] COG1802 Transcriptional regulators
3 IDP00003 gene: gerXC; spore germination protein xc, (pxo1-112) GBAA_pXO1_0158 [Bacillus anthracis str. 'Ames Ancestor'] 317 COG1018 1-316 -9.480 8  [M] COG3317 Uncharacterized lipoprotein
CSGID 3-317 -81.900 16  IDP05381 gene: gerLC; spore germination protein GerLC [Bacillus anthracis str. Ames] BA_0711 [Bacillus anthracis str. Ames]
H.sapiens 15-94 -5.830 11  sp|A8MVP8|CB142_HUMAN Uncharacterized protein C2orf14-like 2 OS=Homo sapiens PE=4 SV=1
HGM_OVER 1-109 -7.860 14  PB029229 gi|150007903|ref|YP_001302646.1| hypothetical protein BDI_1263 [Parabacteroides distasonis ATCC 8503]gi|149936327|gb|ABR43024.1| conserved hypothetical protein [Parabacteroides distasonis ATCC 8503]
NEW_HUMAN_DOMAINS 50-143 -5.890 12  sp|Q8HWS3|RFX6_HUMAN DNA-binding protein RFX6 OS=Homo sapiens GN=RFX6 PE=1 SV=2
PDB1018 26-317 -67.700 15  3n54_B mol:protein length:350 Spore germination protein B3
PfamA32U 218-317 -30.800 14  PF05504.11; C6D3H9_PAESJ/220-385; Spore germination B3/ GerAC like, C-terminal
SCOP207 23-112 -5.730 11  d3ejva1 d.17.4.28 (A:2-160) Uncharacterized protein Saro2766 {Novosphingobium aromaticivorans [TaxId: 48935]}
VFDB 1-316 -9.480 8  [M] COG3317 Uncharacterized lipoprotein
4 IDP00004 Chromosomal replication initiator protein dnaA BA_0001 [Bacillus anthracis str. Ames] 446 COG1018 3-446 -121.000 42  [L] COG0593 ATPase involved in DNA replication initiation
CSGID 7-446 -123.000 35  IDP90747 gene: dnaA; chromosomal replication initiation protein [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0001 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]
H.sapiens 81-322 -11.800 18  sp|Q96S55|WRIP1_HUMAN ATPase WRNIP1 OS=Homo sapiens GN=WRNIP1 PE=1 SV=2
112-344 -13.500 15  sp|Q9NVI7|ATD3A_HUMAN ATPase family AAA domain-containing protein 3A OS=Homo sapiens GN=ATAD3A PE=1 SV=2
147-365 -15.500 16  sp|Q6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 OS=Homo sapiens GN=ATAD2 PE=1 SV=1
147-420 -13.200 13  sp|Q13608|PEX6_HUMAN Peroxisome assembly factor 2 OS=Homo sapiens GN=PEX6 PE=1 SV=2
HGM_OVER 169-353 -3.560 9  HGC00816 gi|163609134|dbj|BABG01026932.1|1.0 TMP01075;
NEW_HUMAN_DOMAINS 179-376 -5.120 11  sp|Q6ZV50|RFX8_HUMAN DNA-binding protein RFX8 OS=Homo sapiens GN=RFX8 PE=2 SV=2
PDB1018 7-446 -121.000 37  2z4r_A mol:protein length:440 Chromosomal replication initiator protein dnaA
PfamA32U 5-68 -17.600 20  PF11638.8; DNAA_LAWIP/5-67; DnaA N-terminal domain
111-329 -101.000 72  PF00308.18; DNAA_STRCO/317-535; Bacterial dnaA protein
147-431 -10.100 15  PF03969.16; ZAPE_ECOLI/4-371; AFG1-like ATPase
356-424 -34.700 68  PF08299.11; D9QS97_ACEAZ/358-426; Bacterial dnaA protein helix-turn-helix
SCOP207 109-324 -92.500 42  d1l8qa2 c.37.1.20 (A:77-289) Chromosomal replication initiation factor DnaA {Aquifex aeolicus [TaxId: 63363]}
341-446 -43.000 30  d1l8qa1 a.4.12.2 (A:290-399) Chromosomal replication initiation factor DnaA C-terminal domain IV {Aquifex aeolicus [TaxId: 63363]}
VFDB 3-446 -121.000 42  [L] COG0593 ATPase involved in DNA replication initiation
5 IDP00005 internalin, putative BA_0552 [Bacillus anthracis str. Ames] 1070 COG1018 3-891 -63.900 12  [S] COG4886 Leucine-rich repeat (LRR) protein
CSGID 2-899 -93.700 16  IDP05663 hypothetical protein lmo0333 [Listeria monocytogenes EGD-e] lmo0333 [Listeria monocytogenes EGD-e]
172-1070 -76.700 18  IDP05666 gene: inlA; internalin A [Listeria monocytogenes EGD-e] lmo0433 [Listeria monocytogenes EGD-e]
H.sapiens 119-435 -34.900 17  sp|Q9H9A6|LRC40_HUMAN Leucine-rich repeat-containing protein 40 OS=Homo sapiens GN=LRRC40 PE=1 SV=1
157-777 -41.300 11  sp|Q05C16|LRC63_HUMAN Leucine-rich repeat-containing protein 63 OS=Homo sapiens GN=LRRC63 PE=2 SV=2
198-787 -55.200 16  sp|P35858|ALS_HUMAN(removed signalp:1-27) Insulin-like growth factor-binding protein complex acid labile subunit OS=Homo sapiens GN=IGFALS PE=1 SV=1
225-833 -52.000 18  sp|A6NIV6|LRIQ4_HUMAN Leucine-rich repeat and IQ domain-containing protein 4 OS=Homo sapiens GN=LRRIQ4 PE=2 SV=2
551-924 -36.800 16  sp|Q86VH4|LRRT4_HUMAN(removed signalp:1-30) Leucine-rich repeat transmembrane neuronal protein 4 OS=Homo sapiens GN=LRRTM4 PE=2 SV=2
HGM_OVER 519-789 -3.680 7  PB022815 A4DEQ0_LISMO/1-452 PB022815; Pfam-B_22815;
NEW_HUMAN_DOMAINS 558-812 -13.600 7  sp|Q6PIJ6|FBX38_HUMAN F-box only protein 38 OS=Homo sapiens GN=FBXO38 PE=1 SV=3
PDB1018 9-787 -65.600 13  5gmf_A mol:protein length:817 Toll-like receptor 7
89-810 -66.200 16  3w3g_A mol:protein length:811 Toll-like receptor 8
222-880 -63.100 16  4z0c_A mol:protein length:709 Toll-like receptor 13
PfamA32U 577-712 -26.600 22  PF14580.6; H3BFR2_LATCH/1-175; Leucine-rich repeat
706-748 -11.400 34  PF12799.7; A4HHM1_LEIBR/66-108; Leucine Rich repeats (2 copies)
SCOP207 202-647 -32.800 15  d1jl5a_ c.10.2.6 (A:) Leucine rich effector protein YopM {Yersinia pestis [TaxId: 632]}
275-761 -53.100 28  d1o6va2 c.10.2.1 (A:36-416) Internalin A {Listeria monocytogenes [TaxId: 1639]}
535-791 -35.100 17  d2o6qa_ c.10.2.0 (A:) automated matches {Inshore hagfish (Eptatretus burgeri) [TaxId: 7764]}
VFDB 3-891 -63.900 12  [S] COG4886 Leucine-rich repeat (LRR) protein
6 IDP00006 immune inhibitor A metalloprotease BA_0672 [Bacillus anthracis str. Ames] 799 COG1018 1-799 -135.000 32  [S] COG4412 Uncharacterized protein conserved in bacteria
CSGID 1-799 -151.000 61  IDP00033 immune inhibitor A metalloprotease BA_1295 [Bacillus anthracis str. Ames]
H.sapiens 49-395 -10.300 9  sp|Q8TE60|ATS18_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 18 OS=Homo sapiens GN=ADAMTS18 PE=2 SV=3
79-410 -11.700 15  sp|Q8WXS8|ATS14_HUMAN(removed signalp:1-22) A disintegrin and metalloproteinase with thrombospondin motifs 14 OS=Homo sapiens GN=ADAMTS14 PE=2 SV=2
HGM_OVER 216-410 -5.590 8  PB005346 A0R807_PELPD/1-258 PB005346; Pfam-B_5346;
NEW_HUMAN_DOMAINS 312-388 -5.840 20  sp|Q5VYV0|FOXB2_HUMAN Forkhead box protein B2 OS=Homo sapiens GN=FOXB2 PE=2 SV=1
PDB1018 50-799 -154.000 98  4yu5_A mol:protein length:756 Immune inhibitor A, metalloprotease
PfamA32U 152-795 -105.000 27  PF05547.11; Q9S2G1_STRCO/100-774; Immune inhibitor A peptidase M6
SCOP207 241-419 -12.300 15  d5d7wa1 d.92.1.0 (A:4-246) automated matches {Serratia marcescens [TaxId: 615]}
311-412 -12.900 23  d1c7ka_ d.92.1.1 (A:) Zinc protease {Streptomyces caespitosus [TaxId: 53502]}
VFDB 1-799 -135.000 32  [S] COG4412 Uncharacterized protein conserved in bacteria
7 IDP00007 gene: racE-1; glutamate racemase BA_0847 [Bacillus anthracis str. Ames] 276 COG1018 2-265 -82.000 26  [M] COG0796 Glutamate racemase
CSGID 6-267 -91.800 46  IDP06272 glutamate racemase [Streptococcus pneumoniae TIGR4] NP_346313 [Streptococcus pneumoniae TIGR4]
H.sapiens 8-185 -8.190 12  sp|Q93075|TATD2_HUMAN Putative deoxyribonuclease TATDN2 OS=Homo sapiens GN=TATDN2 PE=1 SV=2
HGM_OVER 10-118 -3.960 20  PB012991 Q2RHT0_MOOTA/1-175 PB012991; Pfam-B_12991;
NEW_HUMAN_DOMAINS 17-88 -4.930 14  sp|Q6ZN90|PRAML_HUMAN Leucine-rich repeat-containing protein PRAME-like OS=Homo sapiens GN=PRAMEL PE=2 SV=2
PDB1018 1-276 -97.100 100  2dwu_A mol:protein length:276 Glutamate racemase
PfamA32U 10-219 -85.600 37  PF01177.22; R7EMK1_9BACE/12-229; Asp/Glu/Hydantoin racemase
SCOP207 9-112 -62.400 44  d1b74a1 c.78.2.1 (A:1-105) Glutamate racemase {Aquifex pyrophilus [TaxId: 2714]}
113-267 -51.500 34  d1b74a2 c.78.2.1 (A:106-252) Glutamate racemase {Aquifex pyrophilus [TaxId: 2714]}
VFDB 2-265 -82.000 26  [M] COG0796 Glutamate racemase
8 IDP00008 gene: cysG; uroporphyrin-III C-methyltransferase BA_1445 [Bacillus anthracis str. Ames] 258 COG1018 2-257 -98.100 38  [H] COG0007 Uroporphyrinogen-III methylase
CSGID 2-257 -102.000 47  IDP93866 uroporphyrinogen-III methyltransferase [Yersinia enterocolitica subsp. palearctica Y11] YP_006005134 [Yersinia enterocolitica subsp. palearctica Y11]
H.sapiens 4-256 -51.300 18  sp|Q9H2P9|DPH5_HUMAN Diphthine synthase OS=Homo sapiens GN=DPH5 PE=1 SV=2
HGM_OVER 42-233 -4.150 8  HGC00166 gi|163579340|dbj|BABE01005762.1|1.0 TMP00473;
NEW_HUMAN_DOMAINS 3-100 -6.170 14  sp|Q5VW00|DC122_HUMAN DDB1- and CUL4-associated factor 12-like protein 2 OS=Homo sapiens GN=DCAF12L2 PE=2 SV=1
PDB1018 2-257 -100.000 40  2ybq_A mol:protein length:292 METHYLTRANSFERASE
PfamA32U 3-214 -63.000 25  PF00590.20; Q3A6A0_PELCD/39-272; Tetrapyrrole (Corrin/Porphyrin) Methylases
SCOP207 2-247 -98.500 46  d1pjqa2 c.90.1.1 (A:216-457) Siroheme synthase CysG, domains 4 and 5 {Salmonella typhimurium [TaxId: 90371]}
VFDB 2-257 -98.100 38  [H] COG0007 Uroporphyrinogen-III methylase
9 IDP00009 3-dehydroquinate synthase BA_1538 [Bacillus anthracis str. Ames] 363 COG1018 1-354 -96.400 36  [E] COG0337 3-dehydroquinate synthetase
CSGID 1-358 -102.000 38  IDP01058 gene: aroB; 3-dehydroquinate synthase STM3486 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
H.sapiens 14-350 -14.400 12  sp|Q8IWW8|HOT_HUMAN(removed signalp:1-21) Hydroxyacid-oxoacid transhydrogenase, mitochondrial OS=Homo sapiens GN=ADHFE1 PE=1 SV=1
HGM_OVER 76-165 -3.610 17  PB010473 Q8A4J5_BACTN/121-234 PB010473; Pfam-B_10473;
NEW_HUMAN_DOMAINS 95-163 -5.120 16  sp|Q9HAZ2|PRD16_HUMAN PR domain zinc finger protein 16 OS=Homo sapiens GN=PRDM16 PE=1 SV=3
PDB1018 1-358 -103.000 37  5eks_A mol:protein length:368 3-dehydroquinate synthase
PfamA32U 16-269 -39.400 14  PF13685.6; Q162K0_ROSDO/40-301; Iron-containing alcohol dehydrogenase
68-324 -92.300 42  PF01761.20; AROB_SYNY3/68-330; 3-dehydroquinate synthase
SCOP207 1-362 -94.900 30  d1ujna_ e.22.1.1 (A:) Dehydroquinate synthase, DHQS {Thermus thermophilus [TaxId: 274]}
VFDB 1-354 -96.400 36  [E] COG0337 3-dehydroquinate synthetase
10 IDP00010 uroporphyrin-III C-methyltransferase, putative BA_2144 [Bacillus anthracis str. Ames] 474 COG1018 2-269 -82.000 36  [H] COG0007 Uroporphyrinogen-III methylase
244-468 -34.400 15  [H] COG1587 Uroporphyrinogen-III synthase
CSGID 3-468 -97.300 32  IDP91250 gene: lmo1201; lmo1201 [Listeria monocytogenes] NT01LM1295 [Listeria monocytogenes EGD-e]
H.sapiens 4-256 -42.300 16  sp|Q9H2P9|DPH5_HUMAN Diphthine synthase OS=Homo sapiens GN=DPH5 PE=1 SV=2
252-468 -27.200 16  sp|P10746|HEM4_HUMAN Uroporphyrinogen-III synthase OS=Homo sapiens GN=UROS PE=1 SV=1
HGM_OVER 43-233 -3.980 9  HGC00166 gi|163579340|dbj|BABE01005762.1|1.0 TMP00473;
NEW_HUMAN_DOMAINS 4-101 -6.100 16  sp|Q5VW00|DC122_HUMAN DDB1- and CUL4-associated factor 12-like protein 2 OS=Homo sapiens GN=DCAF12L2 PE=2 SV=1
PDB1018 2-268 -82.500 37  1s4d_A mol:protein length:280 Uroporphyrin-III C-methyltransferase
3-298 -54.600 19  2zvb_A mol:protein length:295 Precorrin-3 C17-methyltransferase
251-468 -31.700 14  3mw8_A mol:protein length:240 Uroporphyrinogen-III synthase
PfamA32U 4-214 -53.600 24  PF00590.20; Q3A6A0_PELCD/39-272; Tetrapyrrole (Corrin/Porphyrin) Methylases
264-473 -30.600 13  PF02602.15; Q6AMG2_DESPS/275-509; Uroporphyrinogen-III synthase HemD
SCOP207 3-247 -83.000 46  d1pjqa2 c.90.1.1 (A:216-457) Siroheme synthase CysG, domains 4 and 5 {Salmonella typhimurium [TaxId: 90371]}
253-468 -28.400 11  d1wcwa1 c.113.1.1 (A:10-261) automated matches {Thermus thermophilus [TaxId: 274]}
VFDB 2-269 -82.000 36  [H] COG0007 Uroporphyrinogen-III methylase
244-468 -34.400 15  [H] COG1587 Uroporphyrinogen-III synthase
11 IDP00011 alcohol dehydrogenase, iron-containing BA_2222 [Bacillus anthracis str. Ames] 392 COG1018 1-386 -99.500 33  [C] COG1454 Alcohol dehydrogenase, class IV
CSGID 1-379 -106.000 35  IDP06308 iron-containing alcohol dehydrogenase [Streptococcus pneumoniae TIGR4] NP_346571 [Streptococcus pneumoniae TIGR4]
H.sapiens 2-381 -87.500 30  sp|Q8IWW8|HOT_HUMAN(removed signalp:1-21) Hydroxyacid-oxoacid transhydrogenase, mitochondrial OS=Homo sapiens GN=ADHFE1 PE=1 SV=1
HGM_OVER 40-89 -2.880 16  PB009661 _Gut.Meta.Jp.0000785_ gi|162567239|dbj|BAAU01000237.1||2 (- 3549:4008~0 complete)
NEW_HUMAN_DOMAINS 85-238 -5.370 5  sp|Q9BPY3|F118B_HUMAN Protein FAM118B OS=Homo sapiens GN=FAM118B PE=1 SV=1
PDB1018 1-381 -104.000 37  3zdr_A mol:protein length:433 ALCOHOL DEHYDROGENASE DOMAIN OF THE BIFUNCTIONAL ACETALDEHYDE DEHYDROGENASE
PfamA32U 2-371 -99.500 33  PF00465.19; Q2SC87_HAHCH/11-388; Iron-containing alcohol dehydrogenase
SCOP207 1-379 -95.100 32  d5br4a1 e.22.1.2 (A:1-383) automated matches {Escherichia coli [TaxId: 562]}
VFDB 1-386 -99.500 33  [C] COG1454 Alcohol dehydrogenase, class IV
12 IDP00012 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) BA_2953 [Bacillus anthracis str. Ames] 429 COG1018 1-427 -90.800 23  [E] COG0128 5-enolpyruvylshikimate-3-phosphate synthase
CSGID 10-427 -106.000 49  IDP01842 gene: aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [Coxiella burnetii RSA 493] CBU_0526 [Coxiella burnetii RSA 493]
H.sapiens 17-367 -5.840 9  sp|Q8N9V6|ANR53_HUMAN Ankyrin repeat domain-containing protein 53 OS=Homo sapiens GN=ANKRD53 PE=2 SV=1
HGM_OVER 316-405 -2.740 15  PB162020 _JGI.0344610_ 2004040329 [Human Gut Community Subject 8]
NEW_HUMAN_DOMAINS 340-418 -5.090 15  tr|E7EM71|E7EM71_HUMAN Uncharacterized protein OS=Homo sapiens GN=HDLBP PE=4 SV=1
PDB1018 1-427 -112.000 66  3rmt_A mol:protein length:455 3-phosphoshikimate 1-carboxyvinyltransferase 1
PfamA32U 11-424 -69.100 21  PF00275.20; MURA_ECOLI/6-406; EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
SCOP207 2-427 -108.000 41  d2pqca_ d.68.2.2 (A:) 5-enol-pyruvyl shikimate-3-phosphate (EPSP) synthase {Agrobacterium sp. [TaxId: 268951]}
VFDB 1-427 -90.800 23  [E] COG0128 5-enolpyruvylshikimate-3-phosphate synthase
13 IDP00013 LPXTG-motif cell wall anchor domain protein BA_3254 [Bacillus anthracis str. Ames] 372 COG1018 3-369 -29.400 9  [S] COG1511 Predicted membrane protein
38-316 -32.800 10  [Z] KOG1003 Actin filament-coating protein tropomyosin
CSGID 3-361 -18.200 10  IDP05431 hypothetical protein lmo1224 [Listeria monocytogenes EGD-e] lmo1224 [Listeria monocytogenes EGD-e]
H.sapiens 1-294 -26.700 11  sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus protein 1 OS=Homo sapiens GN=NUMA1 PE=1 SV=2
38-316 -36.100 8  sp|P09493|TPM1_HUMAN Tropomyosin alpha-1 chain OS=Homo sapiens GN=TPM1 PE=1 SV=2
76-369 -29.400 10  sp|Q15075|EEA1_HUMAN Early endosome antigen 1 OS=Homo sapiens GN=EEA1 PE=1 SV=2
HGM_OVER 59-190 -5.690 12  PB202086 Q8G498_BIFLO/2-200 PB202086; Pfam-B_202086;
NEW_HUMAN_DOMAINS 160-325 -8.990 8  sp|Q9UPR0|PLCL2_HUMAN Inactive phospholipase C-like protein 2 OS=Homo sapiens GN=PLCL2 PE=1 SV=2
PDB1018 2-371 -19.000 9  2bsg_A mol:protein length:487 FIBRITIN
38-316 -35.500 8  2tma_A mol:protein length:284 TROPOMYOSIN
77-364 -23.600 8  4lin_A mol:protein length:300 Tail needle protein gp26
PfamA32U 1-372 -15.700 12  PF15358.6; G1M5D4_AILME/26-577; Testis-specific serine kinase substrate
52-331 -23.800 9  PF10174.9; H2T771_TAKRU/113-856; RIM-binding protein of the cytomatrix active zone
SCOP207 139-302 -7.770 11  d1i4ta_ a.238.1.2 (A:) Arfaptin, Rac-binding fragment {Human (Homo sapiens) [TaxId: 9606]}
VFDB 3-369 -29.400 9  [S] COG1511 Predicted membrane protein
38-316 -32.800 10  [Z] KOG1003 Actin filament-coating protein tropomyosin
14 IDP00014 Protein recA (Recombinase A) BA_3915 [Bacillus anthracis str. Ames] 343 COG1018 1-340 -88.100 60  [L] COG0468 RecA/RadA recombinase
CSGID 1-343 -88.600 59  IDP06090 gene: recA; recombinase A [Helicobacter pylori J99] NP_222862 [Helicobacter pylori J99]
H.sapiens 4-271 -39.300 21  sp|O75771|RA51D_HUMAN DNA repair protein RAD51 homolog 4 OS=Homo sapiens GN=RAD51L3 PE=1 SV=1
HGM_OVER 63-161 -5.710 14  PB044863 Q5LB69_BACFN/1-105 PB044863; Pfam-B_44863;
NEW_HUMAN_DOMAINS 44-196 -7.900 12  sp|Q8IVG5|SAM9L_HUMAN Sterile alpha motif domain-containing protein 9-like OS=Homo sapiens GN=SAMD9L PE=1 SV=2
PDB1018 1-343 -88.800 63  1g18_A mol:protein length:350 RECA PROTEIN
PfamA32U 6-267 -83.200 67  PF00154.21; RECA_ACIAD/7-268; recA bacterial DNA recombination protein
53-307 -16.600 8  PF07088.11; GVPD1_HALSA/23-536; GvpD gas vesicle protein
SCOP207 4-266 -83.300 68  d1u94a1 c.37.1.11 (A:6-268) RecA protein, ATPase-domain {Escherichia coli [TaxId: 562]}
267-325 -18.400 37  d1u94a2 d.48.1.1 (A:269-328) RecA protein, C-terminal domain {Escherichia coli [TaxId: 562]}
VFDB 1-340 -88.100 60  [L] COG0468 RecA/RadA recombinase
15 IDP00015 UDP-N-acetylenolpyruvoylglucosamine reductase 1 (UDP-N-acetylmuramate dehydrogenase 1) BA_4048 [Bacillus anthracis str. Ames] 301 COG1018 1-301 -108.000 62  [M] COG0812 UDP-N-acetylmuramate dehydrogenase
CSGID 1-301 -104.000 39  IDP05232 hypothetical protein lmo1420 [Listeria monocytogenes EGD-e] lmo1420 [Listeria monocytogenes EGD-e]
H.sapiens 1-198 -13.100 14  sp|Q15392|DHC24_HUMAN(removed signalp:1-22) 24-dehydrocholesterol reductase OS=Homo sapiens GN=DHCR24 PE=1 SV=2
29-274 -12.900 13  sp|O00116|ADAS_HUMAN Alkyldihydroxyacetonephosphate synthase, peroxisomal OS=Homo sapiens GN=AGPS PE=1 SV=1
HGM_OVER 41-80 -4.140 7  PB009661 _Gut.Meta.Jp.0000785_ gi|162567239|dbj|BAAU01000237.1||2 (- 3549:4008~0 complete)
NEW_HUMAN_DOMAINS 97-301 -4.950 13  sp|Q9UG01|IF172_HUMAN Intraflagellar transport protein 172 homolog OS=Homo sapiens GN=IFT172 PE=1 SV=2
PDB1018 1-301 -109.000 64  4pyt_A mol:protein length:309 UDP-N-acetylenolpyruvoylglucosamine reductase
PfamA32U 35-164 -14.100 14  PF01565.23; Q82SS0_NITEU/46-186; FAD binding domain
201-299 -60.700 50  PF02873.16; Q24TE7_DESHY/186-285; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
SCOP207 2-195 -61.800 39  d1hska1 d.145.1.2 (A:15-208) Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain {Staphylococcus aureus [TaxId: 1280]}
196-301 -63.600 38  d1hska2 d.146.1.1 (A:209-317) Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain {Staphylococcus aureus [TaxId: 1280]}
VFDB 1-301 -108.000 62  [M] COG0812 UDP-N-acetylmuramate dehydrogenase
16 IDP00016 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase) (Meso-diaminopimelate-adding enzyme) (Meso-A2pm-adding enzyme) (UDP-N-acetylmuramyl-tripeptide synthetase) (UDP-MurNAc-tripeptide synthetase) BA_4053 [Bacillus anthracis str. Ames] 491 COG1018 1-488 -124.000 42  [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase
CSGID 1-485 -126.000 43  IDP05067 gene: murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Clostridium difficile 630] CD2664 [Peptoclostridium difficile 630]
H.sapiens 79-458 -23.000 16  sp|Q05932|FOLC_HUMAN(removed signalp:1-19) Folylpolyglutamate synthase, mitochondrial OS=Homo sapiens GN=FPGS PE=1 SV=3
HGM_OVER 336-419 -3.250 15  PB031792 gi|154174791|ref|YP_001409041.1| flavodoxin family protein [Campylobacter curvus 525.92]gi|112804021|gb|EAU01365.1| flavodoxin family protein [Campylobacter curvus 525.92]
NEW_HUMAN_DOMAINS 397-464 -4.860 15  tr|E9PIW9|E9PIW9_HUMAN Uncharacterized protein OS=Homo sapiens GN=SAMD1 PE=4 SV=1
PDB1018 1-491 -128.000 39  4c12_A mol:protein length:501 UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--L-LYSINE LIGASE
PfamA32U 1-259 -23.600 9  PF16292.5; A9WF69_CHLAA/4-305; Domain of unknown function (DUF4938 topsan)
106-312 -76.100 37  PF08245.12; MURE_THEMA/108-304; Mur ligase middle domain
332-418 -51.700 46  PF02875.21; MURE_HELPY/294-375; Mur ligase family, glutamate ligase domain
SCOP207 2-96 -33.100 31  d1e8ca1 c.98.1.1 (A:3-103) UDP-N-acetylmuramyl tripeptide synthetase MurE {Escherichia coli [TaxId: 562]}
97-331 -75.800 31  d1e8ca3 c.72.2.1 (A:104-337) UDP-N-acetylmuramyl tripeptide synthetase MurE {Escherichia coli [TaxId: 562]}
332-487 -67.500 42  d1e8ca2 c.59.1.1 (A:338-494) UDP-N-acetylmuramyl tripeptide synthetase MurE {Escherichia coli [TaxId: 562]}
VFDB 1-488 -124.000 42  [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase
17 IDP00017 gene: ribBA; Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase); GTP cyclohydrolase-2 (GTP cyclohydrolase II)] BA_4333 [Bacillus anthracis str. Ames] 397 COG1018 2-397 -97.200 50  [H] KOG1284 Bifunctional GTP cyclohydrolase II/3,4-dihydroxy-2butanone-4-phosphate synthase
CSGID 2-397 -120.000 54  IDP05201 gene: ribA; riboflavin biosynthesis protein [Clostridium difficile 630] CD1698 [Peptoclostridium difficile 630]
H.sapiens 217-320 -5.270 17  sp|P07202|PERT_HUMAN(removed signalp:1-18) Thyroid peroxidase OS=Homo sapiens GN=TPO PE=1 SV=4
HGM_OVER 236-371 -4.080 14  PB001025 Q1QFV3_NITHX/1-288 PB001025; Pfam-B_1025;
NEW_HUMAN_DOMAINS 319-397 -4.660 19  sp|P15036|ETS2_HUMAN Protein C-ets-2 OS=Homo sapiens GN=ETS2 PE=1 SV=1
PDB1018 2-396 -114.000 56  4i14_A mol:protein length:425 Riboflavin biosynthesis protein RibBA
PfamA32U 6-196 -61.500 53  PF00926.19; R7D2C4_9BACE/10-201; 3,4-dihydroxy-2-butanone 4-phosphate synthase
205-371 -72.200 57  PF00925.20; G4T1J0_META2/10-176; GTP cyclohydrolase II
SCOP207 3-196 -60.900 32  d1snna_ d.115.1.2 (A:) 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB {Methanocaldococcus jannaschii [TaxId: 2190]}
204-375 -73.400 55  d2bz1a_ c.144.1.1 (A:) GTP cyclohydrolase II, RibA {Escherichia coli [TaxId: 562]}
VFDB 2-397 -97.200 50  [H] KOG1284 Bifunctional GTP cyclohydrolase II/3,4-dihydroxy-2butanone-4-phosphate synthase
18 IDP00018 gene: racE-2; glutamate racemase BA_4717 [Bacillus anthracis str. Ames] 269 COG1018 2-262 -82.200 25  [M] COG0796 Glutamate racemase
CSGID 4-268 -95.300 58  IDP00347 gene: racE; hypothetical protein lmo1237 lmo1237 [Listeria monocytogenes EGD-e]
H.sapiens 7-182 -8.110 17  sp|Q93075|TATD2_HUMAN Putative deoxyribonuclease TATDN2 OS=Homo sapiens GN=TATDN2 PE=1 SV=2
HGM_OVER 7-115 -3.950 17  PB012991 Q2RHT0_MOOTA/1-175 PB012991; Pfam-B_12991;
NEW_HUMAN_DOMAINS 14-85 -5.230 15  sp|Q6ZN90|PRAML_HUMAN Leucine-rich repeat-containing protein PRAME-like OS=Homo sapiens GN=PRAMEL PE=2 SV=2
PDB1018 2-268 -95.700 100  2gzm_A mol:protein length:267 Glutamate racemase
PfamA32U 7-216 -86.200 39  PF01177.22; R7EMK1_9BACE/12-229; Asp/Glu/Hydantoin racemase
SCOP207 6-109 -62.700 47  d1b74a1 c.78.2.1 (A:1-105) Glutamate racemase {Aquifex pyrophilus [TaxId: 2714]}
110-266 -49.900 33  d1b74a2 c.78.2.1 (A:106-252) Glutamate racemase {Aquifex pyrophilus [TaxId: 2714]}
VFDB 2-262 -82.200 25  [M] COG0796 Glutamate racemase
19 IDP00019 gene: pykA-2; pyruvate kinase BA_4843 [Bacillus anthracis str. Ames] 585 COG1018 1-472 -122.000 41  [G] COG0469 Pyruvate kinase
475-585 -27.300 63  [T] COG3848 Phosphohistidine swiveling domain
CSGID 1-585 -148.000 60  IDP90253 gene: pyk; pyruvate kinase [Staphylococcus aureus subsp. aureus MRSA252] SAR1776 [Staphylococcus aureus subsp. aureus MRSA252]
H.sapiens 1-473 -122.000 44  sp|P14618|KPYM_HUMAN Pyruvate kinase isozymes M1/M2 OS=Homo sapiens GN=PKM2 PE=1 SV=4
HGM_OVER 107-310 -2.610 12  PB021133 Q64YN4_BACFR/1-310 PB021133; Pfam-B_21133;
NEW_HUMAN_DOMAINS 125-328 -5.510 17  sp|Q7Z2Z1|TICRR_HUMAN Treslin OS=Homo sapiens GN=TICRR PE=1 SV=2
PDB1018 1-585 -150.000 60  3t05_A mol:protein length:606 Pyruvate kinase
PfamA32U 1-343 -101.000 49  PF00224.21; KPYK_EMENI/32-379; Pyruvate kinase, barrel domain
356-469 -41.400 28  PF02887.16; D5C1C2_NITHN/363-477; Pyruvate kinase, alpha/beta domain
506-575 -18.500 40  PF00391.23; I4BU05_ACEMN/423-506; PEP-utilising enzyme, mobile domain
SCOP207 1-337 -79.900 57  d3hqna1 c.1.12.1 (A:1-87,A:187-357) Pyruvate kinase, N-terminal domain {Trypanosome (Leishmania mexicana) [TaxId: 5665]}
354-472 -38.500 34  d1e0ta3 c.49.1.1 (A:354-470) Pyruvate kinase, C-terminal domain {Escherichia coli [TaxId: 562]}
473-581 -24.000 30  d1kbla2 c.8.1.1 (A:377-509) Pyruvate phosphate dikinase, central domain {Clostridium symbiosum [TaxId: 1512]}
VFDB 1-472 -122.000 41  [G] COG0469 Pyruvate kinase
475-585 -27.300 63  [T] COG3848 Phosphohistidine swiveling domain
20 IDP00020 UDP-N-acetylenolpyruvoylglucosamine reductase 2 (UDP-N-acetylmuramate dehydrogenase 2) BA_5315 [Bacillus anthracis str. Ames] 305 COG1018 3-302 -105.000 40  [M] COG0812 UDP-N-acetylmuramate dehydrogenase
CSGID 1-305 -109.000 60  IDP00658 gene: murB; UDP-N-acetylenolpyruvoylglucosamine reductase SACOL0801 [Staphylococcus aureus subsp. aureus COL]
H.sapiens 4-292 -14.300 13  sp|Q8N465|D2HDH_HUMAN(removed signalp:1-22) D-2-hydroxyglutarate dehydrogenase, mitochondrial OS=Homo sapiens GN=D2HGDH PE=1 SV=3
HGM_OVER 70-273 -4.630 9  PB001823 Q5L7Q9_BACFN/1-326 PB001823; Pfam-B_1823;
NEW_HUMAN_DOMAINS 99-301 -5.180 12  sp|Q9UG01|IF172_HUMAN Intraflagellar transport protein 172 homolog OS=Homo sapiens GN=IFT172 PE=1 SV=2
PDB1018 1-305 -107.000 59  1hsk_A mol:protein length:326 UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUCTASE
PfamA32U 38-166 -15.200 20  PF01565.23; Q82SS0_NITEU/46-186; FAD binding domain
202-300 -61.200 52  PF02873.16; Q24TE7_DESHY/186-285; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
SCOP207 4-196 -66.800 50  d1hska1 d.145.1.2 (A:15-208) Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain {Staphylococcus aureus [TaxId: 1280]}
197-305 -64.700 78  d1hska2 d.146.1.1 (A:209-317) Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain {Staphylococcus aureus [TaxId: 1280]}
VFDB 3-302 -105.000 40  [M] COG0812 UDP-N-acetylmuramate dehydrogenase

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. Discovering new genes with advanced homology detection. Trends Biotechnol. 2002 Aug;20(8):315-6.