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# Query Length Result vs. Range Score %id Covered by template(s)
1 gi|108885075|ref|NP_072661.2| DNA polymerase III, beta subunit (MG_001) [Mycoplasma genitalium G37] 380 COG1018 1-380 -86.600 19  [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
CSGID 1-380 -94.700 21  IDP04571 DNA polymerase III subunit beta [Bacillus anthracis str. Sterne] BAS0002 [Bacillus anthracis str. Sterne]
H.sapiens 133-377 -8.090 11  sp|Q6WBX8|RAD9B_HUMAN Cell cycle checkpoint control protein RAD9B OS=Homo sapiens GN=RAD9B PE=1 SV=2
HGM_OVER 3-358 -4.540 PB004476 gi|139436894|ref|ZP_01771054.1| Hypothetical protein COLAER_00025 [Collinsella aerofaciens ATCC 25986]gi|133776541|gb|EBA40361.1| Hypothetical protein COLAER_00025 [Collinsella aerofaciens ATCC 25986]
NEW_HUMAN_DOMAINS 23-88 -5.320 12  sp|Q6ZTY8|CL063_HUMAN Putative uncharacterized protein C12orf63 OS=Homo sapiens GN=C12orf63 PE=2 SV=2
PDB1018 1-380 -95.800 21  4tr6_A mol:protein length:380 DNA polymerase III subunit beta
PfamA32U 1-120 -43.600 20  PF00712.19; DPO3B_CAUVC/1-121; DNA polymerase III beta subunit, N-terminal domain
135-256 -39.300 12  PF02767.16; DPO3B_PSEPK/129-244; DNA polymerase III beta subunit, central domain
258-380 -52.600 29  PF02768.15; DPO3B_BACSU/253-376; DNA polymerase III beta subunit, C-terminal domain
SCOP207 1-121 -47.400 21  d1vpka1 d.131.1.1 (A:1-120) DNA polymerase III, beta subunit {Thermotoga maritima [TaxId: 2336]}
129-257 -40.400 14  d4k3la2 d.131.1.1 (A:123-244) DNA polymerase III, beta subunit {Escherichia coli [TaxId: 562]}
258-380 -51.500 19  d4k3la3 d.131.1.1 (A:245-365) DNA polymerase III, beta subunit {Escherichia coli [TaxId: 562]}
VFDB 1-380 -86.600 19  [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
2 gi|108885076|ref|NP_072662.2| DnaJ domain-containing protein (MG_002) [Mycoplasma genitalium G37] 310 COG1018 2-309 -91.000 17  [O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain
CSGID 2-309 -92.300 20  IDP01653 gene: dnaJ; chaperone protein dnaJ [Bacillus anthracis str. `Ames Ancestor`] GBAA4538 [Bacillus anthracis str. `Ames Ancestor`]
H.sapiens 2-310 -85.000 16  sp|O75953|DNJB5_HUMAN DnaJ homolog subfamily B member 5 OS=Homo sapiens GN=DNAJB5 PE=2 SV=1
HGM_OVER 5-49 -6.680 17  PB002794 gi|86143885|ref|ZP_01062253.1| hypothetical protein MED217_03525 [Flavobacterium sp. MED217]gi|85829592|gb|EAQ48055.1| hypothetical protein MED217_03525 [Leeuwenhoekiella blandensis MED217]
NEW_HUMAN_DOMAINS 1-59 -7.370 13  sp|Q9UBC1|IKBL1_HUMAN NF-kappa-B inhibitor-like protein 1 OS=Homo sapiens GN=NFKBIL1 PE=1 SV=1
PDB1018 2-309 -78.000 17  3lz8_A mol:protein length:329 Putative chaperone DnaJ
PfamA32U 2-61 -35.800 46  PF00226.31; Q22028_CAEEL/17-79; DnaJ domain
121-309 -51.700 10  PF01556.18; T0NBZ6_9EURY/129-343; DnaJ C terminal domain
SCOP207 2-76 -41.500 33  d2o37a_ a.2.3.0 (A:) automated matches {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
115-278 -9.800 10  d3agxa2 b.4.1.0 (A:246-340) automated matches {Human (Homo sapiens) [TaxId: 9606]}
135-223 -17.200 d1exka_ g.54.1.1 (A:) Cysteine-rich domain of the chaperone protein DnaJ {Escherichia coli [TaxId: 562]}
195-266 -17.900 15  d2q2ga1 b.4.1.0 (A:4-86) automated matches {Cryptosporidium parvum [TaxId: 353152]}
VFDB 2-309 -91.000 17  [O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain
3 gi|12044853|ref|NP_072663.1| DNA gyrase subunit B (MG_003) [Mycoplasma genitalium G37] 650 COG1018 3-650 -150.000 47  [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
CSGID 2-650 -200.000 53  IDP04572 DNA gyrase subunit B [Bacillus anthracis str. Sterne] BAS0005 [Bacillus anthracis str. Sterne]
H.sapiens 2-272 -70.300 21  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3
87-410 -80.200 18  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3
277-573 -102.000 24  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3
411-650 -84.900 27  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3
HGM_OVER 396-649 -3.120 PB015879 Q5LJ14_BACFN/120-411 PB015879; Pfam-B_15879;
NEW_HUMAN_DOMAINS 439-535 -6.650 13  sp|Q14703|MBTP1_HUMAN Membrane-bound transcription factor site-1 protease OS=Homo sapiens GN=MBTPS1 PE=1 SV=1
PDB1018 2-650 -181.000 44  4juo_C mol:protein length:670 DNA topoisomerase 4 subunit B
PfamA32U 39-144 -13.700 18  PF13589.6; A5G4D8_GEOUR/22-165; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
228-408 -58.000 39  PF00204.25; A9KS52_LACP7/226-396; DNA gyrase B
546-645 -30.000 17  PF16898.5; K5XBZ3_PHACS/641-767; C-terminal associated domain of TOPRIM
577-639 -31.100 63  PF00986.21; M9X0E0_MANHA/738-800; DNA gyrase B subunit, carboxyl terminus
SCOP207 20-227 -79.900 52  d4k4oa1 d.122.1.0 (A:18-224) automated matches {Enterococcus faecalis [TaxId: 226185]}
228-409 -57.100 36  d1kija1 d.14.1.3 (A:221-392) DNA gyrase B {Thermus thermophilus [TaxId: 274]}
411-644 -48.900 28  d1bjta_ e.11.1.1 (A:) DNA topoisomerase II, C-terminal fragment (residues 410-1202) {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
430-629 -95.200 57  d3m4ia_ e.78.1.1 (A:) DNA gyrase beta-prime domain {Mycobacterium tuberculosis [TaxId: 1773]}
VFDB 3-650 -150.000 47  [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
4 gi|12044854|ref|NP_072664.1| DNA gyrase subunit A (MG_004) [Mycoplasma genitalium G37] 836 COG1018 15-836 -157.000 38  [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
CSGID 14-836 -163.000 45  IDP90834 DNA gyrase, subunit A [Vibrio cholerae O1 biovar eltor str. N16961] VC1258 [Vibrio cholerae O1 biovar El Tor str. N16961]
H.sapiens 2-234 -45.500 25  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3
61-370 -55.600 21  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3
239-496 -23.200 12  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3
246-538 -22.600 13  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3
HGM_OVER 23-189 -2.010 14  HGC00690 gi|162868815|dbj|BABB01001192.1|3.0 TMP00870;
NEW_HUMAN_DOMAINS 49-181 -5.260 21  sp|Q9H1B7|I2BPL_HUMAN Interferon regulatory factor 2-binding protein-like OS=Homo sapiens GN=IRF2BPL PE=1 SV=1
PDB1018 1-497 -116.000 41  4i3h_A mol:protein length:1144 Topoisomerase IV subunit B, DNA topoisomerase 4 subunit A chimera
42-762 -123.000 31  1zvu_A mol:protein length:716 Topoisomerase IV subunit A
512-817 -38.100 38  1zi0_A mol:protein length:307 DNA gyrase subunit A
PfamA32U 44-477 -61.100 19  PF00521.20; A0A0D1DXS4_USTMA/785-1232; DNA gyrase/topoisomerase IV, subunit A
SCOP207 2-528 -63.100 16  d1bjta_ e.11.1.1 (A:) DNA topoisomerase II, C-terminal fragment (residues 410-1202) {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
42-498 -104.000 49  d3ilwa_ e.11.1.0 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
512-817 -37.100 33  d4g3na_ b.68.10.0 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
VFDB 15-836 -157.000 38  [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
5 gi|12044855|ref|NP_072665.1| seryl-tRNA synthetase (MG_005) [Mycoplasma genitalium G37] 417 COG1018 1-416 -129.000 42  [J] COG0172 Seryl-tRNA synthetase
CSGID 1-411 -131.000 43  IDP90689 gene: serS; seryl-tRNA synthetase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0389 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]
H.sapiens 1-417 -116.000 25  sp|P49591|SYSC_HUMAN Seryl-tRNA synthetase, cytoplasmic OS=Homo sapiens GN=SARS PE=1 SV=3
HGM_OVER 213-407 -3.460 10  PB064361 Q64PJ4_BACFR/1-580 PB064361; Pfam-B_64361;
NEW_HUMAN_DOMAINS 244-410 -5.710 17  tr|E5RG91|E5RG91_HUMAN Uncharacterized protein OS=Homo sapiens GN=VPS37A PE=4 SV=1
PDB1018 1-416 -127.000 43  2dq3_A mol:protein length:425 Seryl-tRNA synthetase
PfamA32U 1-104 -29.100 21  PF02403.22; C5WTV8_SORBI/1-114; Seryl-tRNA synthetase N-terminal domain
212-394 -13.500 18  PF00587.25; SYT_ECOLI/318-529; tRNA synthetase class II core domain (G, H, P, S and T)
SCOP207 1-109 -33.400 22  d1seta1 a.2.7.1 (A:1-110) Seryl-tRNA synthetase (SerRS) {Thermus thermophilus, strain hb27 [TaxId: 274]}
112-417 -115.000 36  d1seta2 d.104.1.1 (A:111-421) Seryl-tRNA synthetase (SerRS) {Thermus thermophilus, strain hb27 [TaxId: 274]}
VFDB 1-416 -129.000 42  [J] COG0172 Seryl-tRNA synthetase
6 gi|12044856|ref|NP_072666.1| thymidylate kinase (MG_006) [Mycoplasma genitalium G37] 210 COG1018 3-210 -85.400 31  [F] COG0125 Thymidylate kinase
CSGID 3-209 -86.100 32  IDP90611 gene: tmk; thymidylate kinase [Vibrio cholerae O1 biovar eltor str. N16961] VC2016 [Vibrio cholerae O1 biovar El Tor str. N16961]
H.sapiens 1-207 -68.500 20  sp|P23919|KTHY_HUMAN Thymidylate kinase OS=Homo sapiens GN=DTYMK PE=1 SV=4
HGM_OVER 85-121 -3.160 16  PB004718 Q5LIA4_BACFN/1-189 PB004718; Pfam-B_4718;
NEW_HUMAN_DOMAINS 2-46 -5.690 tr|F8WBB3|F8WBB3_HUMAN Uncharacterized protein OS=Homo sapiens GN=ABHD1 PE=4 SV=1
PDB1018 1-204 -89.700 30  3v9p_A mol:protein length:227 Thymidylate kinase
PfamA32U 9-197 -84.800 34  PF02223.17; KTHY_BACSU/8-199; Thymidylate kinase
SCOP207 4-206 -88.100 27  d4hlca_ c.37.1.0 (A:) automated matches {Staphylococcus aureus [TaxId: 282458]}
VFDB 3-210 -85.400 31  [F] COG0125 Thymidylate kinase
7 gi|12044857|ref|NP_072667.1| DNA polymerase III subunit delta' (MG_007) [Mycoplasma genitalium G37] 254 COG1018 2-254 -77.300 16  [L] COG2812 DNA polymerase III, gamma/tau subunits
CSGID 2-254 -72.300 19  IDP90891 gene: dnaX; DNA polymerase III subunits gamma and tau [Yersinia pestis CO92] YPO3122 [Yersinia pestis CO92]
H.sapiens 2-254 -56.400 sp|P35250|RFC2_HUMAN Replication factor C subunit 2 OS=Homo sapiens GN=RFC2 PE=1 SV=3
HGM_OVER 76-239 -3.980 11  PB007011 gi|160888195|ref|ZP_02069198.1| hypothetical protein BACUNI_00603 [Bacteroides uniformis ATCC 8492]gi|156862330|gb|EDO55761.1| hypothetical protein BACUNI_00603 [Bacteroides uniformis ATCC 8492]
NEW_HUMAN_DOMAINS 19-221 -6.080 10  sp|Q504Y0|S39AC_HUMAN Zinc transporter ZIP12 OS=Homo sapiens GN=SLC39A12 PE=2 SV=3
PDB1018 2-205 -88.700 20  1njf_A mol:protein length:250 DNA polymerase III subunit gamma
2-254 -83.800 17  3glf_B mol:protein length:395 DNA polymerase III subunit tau
PfamA32U 2-143 -72.100 23  PF13177.6; A5VIC8_LACRD/13-171; DNA polymerase III, delta subunit
2-222 -22.800 PF05673.13; Q0K6N5_CUPNH/29-287; Protein of unknown function (DUF815 topsan)
194-254 -9.830 PF12169.8; Q11B01_CHESB/247-389; DNA polymerase III subunits gamma and tau domain III
SCOP207 2-205 -90.100 20  d1njfa_ c.37.1.20 (A:) delta prime subunit of DNA polymerase III, N-domain {Escherichia coli [TaxId: 562]}
3-239 -11.900 10  d2x8aa_ c.37.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
VFDB 2-254 -77.300 16  [L] COG2812 DNA polymerase III, gamma/tau subunits
8 gi|12044858|ref|NP_072668.1| tRNA modification GTPase TrmE (MG_008) [Mycoplasma genitalium G37] 442 COG1018 1-442 -118.000 28  [R] COG0486 Predicted GTPase
CSGID 3-442 -118.000 28  IDP01354 gene: trmE; tRNA modification GTPase TrmE VC0003 [Vibrio cholerae O1 biovar El Tor str. N16961]
H.sapiens 2-442 -117.000 24  sp|Q969Y2|GTPB3_HUMAN tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens GN=GTPBP3 PE=2 SV=2
HGM_OVER 9-442 -2.950 10  PB002589 gi|91201099|emb|CAJ74158.1| hypothetical protein [Candidatus Kuenenia stuttgartiensis]
NEW_HUMAN_DOMAINS 10-113 -4.990 14  sp|Q10571|MN1_HUMAN Probable tumor suppressor protein MN1 OS=Homo sapiens GN=MN1 PE=1 SV=3
PDB1018 2-442 -119.000 26  3gee_A mol:protein length:476 tRNA modification GTPase mnmE
PfamA32U 6-121 -56.500 40  PF10396.9; A4CKF7_ROBBH/5-124; GTP-binding protein TrmE N-terminus
124-439 -82.400 26  PF12631.7; D5XDU4_THEPJ/127-455; MnmE helical domain
SCOP207 5-121 -58.900 42  d1xzpa3 d.250.1.2 (A:1-117) TrmE formyl-THF-binding domain {Thermotoga maritima [TaxId: 2336]}
122-442 -40.500 25  d1xzpa1 a.24.25.1 (A:118-211,A:372-450) TrmE connector domain {Thermotoga maritima [TaxId: 2336]}
217-362 -54.400 30  d2gj8a_ c.37.1.8 (A:) automated matches {Escherichia coli [TaxId: 469008]}
VFDB 1-442 -118.000 28  [R] COG0486 Predicted GTPase
9 gi|12044859|ref|NP_072669.1| TatD family deoxyribonuclease (MG_009) [Mycoplasma genitalium G37] 262 COG1018 1-261 -107.000 27  [L] COG0084 Mg-dependent DNase
CSGID 1-261 -102.000 30  IDP00957 gene: ycfH; predicted metallodependent hydrolase STM1202 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
H.sapiens 1-262 -93.800 23  sp|Q17R31|TATD3_HUMAN Putative deoxyribonuclease TATDN3 OS=Homo sapiens GN=TATDN3 PE=1 SV=1
HGM_OVER 115-259 -3.490 12  PB002104 Q72PH8_LEPIC/1-220 PB002104; Pfam-B_2104;
NEW_HUMAN_DOMAINS 178-260 -6.340 10  sp|P14543|NID1_HUMAN Nidogen-1 OS=Homo sapiens GN=NID1 PE=1 SV=3
PDB1018 1-261 -104.000 31  1j6o_A mol:protein length:268 TatD-related deoxyribonuclease
PfamA32U 4-260 -102.000 29  PF01026.21; Y454_HAEIN/4-256; TatD related DNase
SCOP207 3-261 -104.000 31  d1j6oa1 c.1.9.12 (A:0-255) Hypothetical protein TM0667 {Thermotoga maritima [TaxId: 2336]}
VFDB 1-261 -107.000 27  [L] COG0084 Mg-dependent DNase
10 gi|12044860|ref|NP_072670.1| DNA primase-related protein (MG_010) [Mycoplasma genitalium G37] 218 COG1018 2-218 -63.400 18  [L] COG0358 DNA primase (bacterial type)
CSGID 2-218 -63.400 18  IDP90503 DNA primase [Vibrio cholerae O1 biovar eltor str. N16961] NP_230169 [Vibrio cholerae O1 biovar El Tor str. N16961]
H.sapiens 24-218 -34.400 16  sp|Q96RR1|PEO1_HUMAN(removed signalp:1-19) Twinkle protein, mitochondrial OS=Homo sapiens GN=PEO1 PE=1 SV=1
HGM_OVER 6-159 -3.050 12  PB012991 Q2RHT0_MOOTA/1-175 PB012991; Pfam-B_12991;
NEW_HUMAN_DOMAINS 64-168 -4.870 sp|Q8N122|RPTOR_HUMAN Regulatory-associated protein of mTOR OS=Homo sapiens GN=RPTOR PE=1 SV=1
PDB1018 2-218 -75.900 18  5guj_A mol:protein length:324 DNA primase
PfamA32U 2-106 -40.700 10  PF08275.11; Q8F416_LEPIN/119-248; DNA primase catalytic core, N-terminal domain
114-201 -42.100 22  PF13155.6; Q8EPY5_OCEIH/263-348; Toprim-like
SCOP207 3-218 -73.800 19  d1dd9a_ e.13.1.1 (A:) DNA primase DnaG catalytic core {Escherichia coli [TaxId: 562]}
VFDB 2-218 -63.400 18  [L] COG0358 DNA primase (bacterial type)
11 gi|12044861|ref|NP_072671.1| hypothetical protein (MG_011) [Mycoplasma genitalium G37] 287 COG1018 2-284 -55.400 11  [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
CSGID 6-282 -31.100 14  IDP02693 gene: ddlB; D-alanine--D-alanine ligase B [Francisella tularensis subsp. tularensis SCHU S4] FTT0185 [Francisella tularensis subsp. tularensis SCHU S4]
H.sapiens 6-284 -74.700 15  sp|Q8IXN7|RIMKA_HUMAN Ribosomal protein S6 modification-like protein A OS=Homo sapiens GN=RIMKLA PE=2 SV=2
HGM_OVER 187-284 -3.520 16  PB046158 _JGI.0336690_ 2004028347 [Human Gut Community Subject 8]
NEW_HUMAN_DOMAINS 74-276 -4.520 11  sp|A5YM72|CRNS1_HUMAN Carnosine synthase 1 OS=Homo sapiens GN=CARNS1 PE=1 SV=3
PDB1018 9-279 -78.700 16  3vpb_A mol:protein length:282 Putative acetylornithine deacetylase
PfamA32U 9-91 -15.500 PF18030.1; D3SB52_THISK/1-94; RimK PreATP-grasp domain
94-273 -68.400 19  PF08443.11; RIMK_HAEIN/105-293; RimK-like ATP-grasp domain
SCOP207 21-96 -18.700 13  d3vpda1 c.30.1.0 (A:1-88) automated matches {Thermus thermophilus [TaxId: 274]}
97-279 -66.000 16  d3vpda2 d.142.1.7 (A:89-281) automated matches {Thermus thermophilus [TaxId: 274]}
VFDB 2-284 -55.400 11  [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
12 gi|12044862|ref|NP_072672.1| alpha-L-glutamate ligase (MG_012) [Mycoplasma genitalium G37] 287 COG1018 1-287 -54.000 19  [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
CSGID 2-287 -27.800 12  IDP00575 gene: ddl; D-alanine--D-alanine ligase YPO0557 [Yersinia pestis CO92]
H.sapiens 1-287 -69.300 23  sp|Q8IXN7|RIMKA_HUMAN Ribosomal protein S6 modification-like protein A OS=Homo sapiens GN=RIMKLA PE=2 SV=2
HGM_OVER 203-287 -2.890 PB046158 _JGI.0336690_ 2004028347 [Human Gut Community Subject 8]
NEW_HUMAN_DOMAINS 74-240 -5.760 13  sp|A5YM72|CRNS1_HUMAN Carnosine synthase 1 OS=Homo sapiens GN=CARNS1 PE=1 SV=3
PDB1018 1-287 -71.200 19  3vpb_A mol:protein length:282 Putative acetylornithine deacetylase
PfamA32U 1-87 -14.900 19  PF18030.1; D3SB52_THISK/1-94; RimK PreATP-grasp domain
90-287 -66.500 23  PF08443.11; RIMK_HAEIN/105-293; RimK-like ATP-grasp domain
SCOP207 3-92 -16.100 14  d3vpda1 c.30.1.0 (A:1-88) automated matches {Thermus thermophilus [TaxId: 274]}
82-287 -61.700 12  d1i7na2 d.142.1.3 (A:215-420) Synapsin II {Norway rat (Rattus norvegicus) [TaxId: 10116]}
VFDB 1-287 -54.000 19  [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
13 gi|108885077|ref|NP_072673.2| methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase (MG_013) [Mycoplasma genitalium G37] 273 COG1018 2-266 -103.000 28  [H] COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
CSGID 2-267 -106.000 30  IDP90810 gene: folD; folD bifunctional protein [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0855 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]
H.sapiens 2-271 -102.000 28  sp|P11586|C1TC_HUMAN C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens GN=MTHFD1 PE=1 SV=3
HGM_OVER 145-272 -3.270 16  PB012991 Q2RHT0_MOOTA/1-175 PB012991; Pfam-B_12991;
NEW_HUMAN_DOMAINS 205-253 -5.470 14  tr|B0UZT8|B0UZT8_HUMAN Chromosome 6 open reading frame 10 (Fragment) OS=Homo sapiens GN=C6orf10 PE=4 SV=1
PDB1018 2-267 -106.000 30  3p2o_A mol:protein length:285 Bifunctional protein folD
PfamA32U 2-111 -49.500 31  PF00763.23; FOLD_BACSK/6-121; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
114-264 -68.800 23  PF02882.19; FOLD1_ARATH/184-349; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
SCOP207 1-112 -50.400 33  d4b4ua1 c.58.1.0 (A:1-121) automated matches {Acinetobacter baumannii [TaxId: 575584]}
113-267 -66.800 26  d4cjxa2 c.2.1.0 (A:125-297) automated matches {Trypanosoma brucei [TaxId: 999953]}
VFDB 2-266 -103.000 28  [H] COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
14 gi|12044864|ref|NP_072674.1|(removed signalp:1-25) ABC transporter, ATP-binding/permease protein (MG_014) [Mycoplasma genitalium G37] 598 COG1018 1-590 -121.000 23  [V] COG1132 ABC-type multidrug transport system, ATPase and permease components
CSGID 1-597 -125.000 19  IDP91071 putative ABC transporter, ATP-binding protein [Neisseria gonorrhoeae FA 1090] NGO2165 [Neisseria gonorrhoeae FA 1090]
H.sapiens 14-321 -51.200 12  sp|Q9NUT2|ABCB8_HUMAN ATP-binding cassette sub-family B member 8, mitochondrial OS=Homo sapiens GN=ABCB8 PE=1 SV=3
71-377 -58.200 17  sp|Q03518|TAP1_HUMAN Antigen peptide transporter 1 OS=Homo sapiens GN=TAP1 PE=1 SV=2
153-469 -63.900 23  sp|Q9NP78|ABCB9_HUMAN(removed signalp:1-23) ATP-binding cassette sub-family B member 9 OS=Homo sapiens GN=ABCB9 PE=1 SV=1
195-512 -71.500 24  sp|Q9NP58|ABCB6_HUMAN ATP-binding cassette sub-family B member 6, mitochondrial OS=Homo sapiens GN=ABCB6 PE=1 SV=1
245-557 -73.500 29  sp|P08183|MDR1_HUMAN Multidrug resistance protein 1 OS=Homo sapiens GN=ABCB1 PE=1 SV=3
311-596 -82.800 33  sp|Q9NP78|ABCB9_HUMAN(removed signalp:1-23) ATP-binding cassette sub-family B member 9 OS=Homo sapiens GN=ABCB9 PE=1 SV=1
HGM_OVER 412-595 -3.940 10  HGC00374 gi|162831834|dbj|BABA01012875.1|1.0 TMP00304;
NEW_HUMAN_DOMAINS 338-549 -4.390 11  sp|Q8IVG5|SAM9L_HUMAN Sterile alpha motif domain-containing protein 9-like OS=Homo sapiens GN=SAMD9L PE=1 SV=2
PDB1018 1-595 -123.000 24  3qf4_B mol:protein length:598 Uncharacterized ABC transporter ATP-binding protein TM_0288
PfamA32U 16-296 -11.300 15  PF00664.23; ABCC8_CRICR/318-590; ABC transporter transmembrane region
306-577 -18.600 13  PF09818.9; Q10V01_TRIEI/4-493; Predicted ATPase of the ABC class
358-517 -29.300 22  PF00005.27; YTFR_ECOLI/25-174; ABC transporter
SCOP207 1-325 -53.300 16  d5mkka1 f.37.1.0 (A:11-336) automated matches {Thermus thermophilus [TaxId: 262724]}
340-591 -82.300 31  d1mv5a_ c.37.1.12 (A:) Multidrug resistance ABC transporter LmrA, C-terminal domain {Lactococcus lactis [TaxId: 1358]}
VFDB 1-590 -121.000 23  [V] COG1132 ABC-type multidrug transport system, ATPase and permease components
15 gi|12044865|ref|NP_072675.1|(removed signalp:1-25) ABC transporter, ATP-binding/permease protein (MG_015) [Mycoplasma genitalium G37] 564 COG1018 3-564 -124.000 29  [V] COG1132 ABC-type multidrug transport system, ATPase and permease components
CSGID 3-564 -140.000 33  IDP91084 ABC transporter, ATP-binding/permease protein [Bacillus anthracis str. Ames] BA_2444 [Bacillus anthracis str. Ames]
H.sapiens 3-306 -53.700 14  sp|Q9NUT2|ABCB8_HUMAN ATP-binding cassette sub-family B member 8, mitochondrial OS=Homo sapiens GN=ABCB8 PE=1 SV=3
58-362 -62.800 18  sp|Q03518|TAP1_HUMAN Antigen peptide transporter 1 OS=Homo sapiens GN=TAP1 PE=1 SV=2
140-444 -68.400 23  sp|Q9NP78|ABCB9_HUMAN(removed signalp:1-23) ATP-binding cassette sub-family B member 9 OS=Homo sapiens GN=ABCB9 PE=1 SV=1
182-487 -80.100 30  sp|Q9NP58|ABCB6_HUMAN ATP-binding cassette sub-family B member 6, mitochondrial OS=Homo sapiens GN=ABCB6 PE=1 SV=1
288-562 -85.400 36  sp|Q9NRK6|ABCBA_HUMAN ATP-binding cassette sub-family B member 10, mitochondrial OS=Homo sapiens GN=ABCB10 PE=1 SV=2
322-564 -90.300 40  sp|O75027|ABCB7_HUMAN(removed signalp:1-16) ATP-binding cassette sub-family B member 7, mitochondrial OS=Homo sapiens GN=ABCB7 PE=1 SV=2
HGM_OVER 435-543 -4.640 11  PB202086 Q8G498_BIFLO/2-200 PB202086; Pfam-B_202086;
NEW_HUMAN_DOMAINS 435-543 -4.650 20  sp|Q86UK5|LBN_HUMAN Limbin OS=Homo sapiens GN=EVC2 PE=1 SV=1
PDB1018 3-564 -139.000 33  3qf4_B mol:protein length:598 Uncharacterized ABC transporter ATP-binding protein TM_0288
PfamA32U 44-282 -9.910 16  PF00664.23; ABCC8_CRICR/318-590; ABC transporter transmembrane region
284-552 -19.800 13  PF09818.9; Q10V01_TRIEI/4-493; Predicted ATPase of the ABC class
343-492 -30.000 28  PF00005.27; YTFR_ECOLI/25-174; ABC transporter
SCOP207 3-311 -57.300 22  d4q4hb1 f.37.1.0 (B:10-339) automated matches {Thermotoga maritima [TaxId: 243274]}
327-564 -89.900 36  d1mv5a_ c.37.1.12 (A:) Multidrug resistance ABC transporter LmrA, C-terminal domain {Lactococcus lactis [TaxId: 1358]}
VFDB 3-564 -124.000 29  [V] COG1132 ABC-type multidrug transport system, ATPase and permease components
16 gi|108885078|ref|NP_072678.2| SNF2 family helicase putative (MG_018) [Mycoplasma genitalium G37] 500 COG1018 1-118 -11.900 17  [S] COG4715 Uncharacterized conserved protein
CSGID 58-93 -4.620 13  IDP90175 gene: VGF; CPXV021 protein or CPXV VGF protein AAM13468.1 [Cowpox virus (Brighton Red)]
H.sapiens 1-253 -15.500 14  sp|Q9HCJ5|ZSWM6_HUMAN Zinc finger SWIM domain-containing protein 6 OS=Homo sapiens GN=ZSWIM6 PE=2 SV=2
12-100 -15.600 22  sp|Q9HCJ5|ZSWM6_HUMAN Zinc finger SWIM domain-containing protein 6 OS=Homo sapiens GN=ZSWIM6 PE=2 SV=2
HGM_OVER 45-109 -2.830 13  HGC00991 gi|163600283|dbj|BABF01000984.1|3.0 TMP01348;
NEW_HUMAN_DOMAINS 12-118 -18.000 18  sp|Q9HCJ5|ZSWM6_HUMAN Zinc finger SWIM domain-containing protein 6 OS=Homo sapiens GN=ZSWIM6 PE=2 SV=2
PDB1018 9-82 -7.160 20  6dex_B mol:protein length:201 Suppressor of hydroxyurea sensitivity protein 2
PfamA32U 45-84 -12.000 42  PF04434.17; Y020_MYCPN/46-86; SWIM zinc finger
SCOP207 54-93 -5.330 22  d1q8da_ a.228.1.1 (A:) GDNF receptor alpha {Norway rat (Rattus norvegicus) [TaxId: 10116]}
VFDB 1-118 -11.900 17  [S] COG4715 Uncharacterized conserved protein
17 gi|108885078|ref|NP_072678.2| SNF2 family helicase putative (MG_018) [Mycoplasma genitalium G37] 500 COG1018 30-500 -68.800 21  [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family
CSGID 218-500 -12.600 13  IDP93842 ATP-dependent DNA helicase RecG [Yersinia enterocolitica subsp. palearctica Y11] YP_006006418 [Yersinia enterocolitica subsp. palearctica Y11]
262-500 -30.900 30  IDP06036 SNF2 family N-terminal domain-containing protein [Toxoplasma gondii ME49] XP_002371474 [Toxoplasma gondii ME49]
300-500 -39.300 12  IDP06471 gene: E11L; E11L [Monkeypox virus Zaire-96-I-16] NP_536535 [Monkeypox virus Zaire-96-I-16]
H.sapiens 120-400 -50.800 16  sp|O14981|BTAF1_HUMAN TATA-binding protein-associated factor 172 OS=Homo sapiens GN=BTAF1 PE=1 SV=2
223-495 -63.200 18  sp|Q14527|HLTF_HUMAN Helicase-like transcription factor OS=Homo sapiens GN=HLTF PE=1 SV=2
273-500 -73.000 29  sp|O14981|BTAF1_HUMAN TATA-binding protein-associated factor 172 OS=Homo sapiens GN=BTAF1 PE=1 SV=2
HGM_OVER 297-500 -3.750 11  HGC00166 gi|163579340|dbj|BABE01005762.1|1.0 TMP00473;
NEW_HUMAN_DOMAINS 384-490 -5.200 17  tr|Q5VUY5|Q5VUY5_HUMAN Chromosome 1 open reading frame 158 OS=Homo sapiens GN=C1orf158 PE=2 SV=1
PDB1018 127-496 -11.700 11  4xqk_A mol:protein length:1578 LlaBIII
198-500 -35.700 14  4s20_K mol:protein length:974 RNA polymerase-associated protein RapA
300-500 -57.700 38  1z63_A mol:protein length:500 Helicase of the snf2/rad54 family
PfamA32U 5-321 -23.900 10  PF08455.10; R4KHE0_9FIRM/244-621; Bacterial SNF2 helicase associated
331-500 -46.100 29  PF00176.23; RAD54_SCHPO/267-575; SNF2 family N-terminal domain
SCOP207 272-483 -23.300 17  d2fz4a1 c.37.1.19 (A:24-229) DNA repair protein RAD25 {Archaeoglobus fulgidus [TaxId: 2234]}
317-500 -71.300 41  d1z63a1 c.37.1.19 (A:432-661) Helicase of the SNF2/Rad54 hamily {Sulfolobus solfataricus [TaxId: 2287]}
VFDB 30-500 -68.800 21  [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family
18 gi|108885078|ref|NP_072678.2| SNF2 family helicase putative (MG_018) [Mycoplasma genitalium G37] 500 COG1018 1-500 -108.000 33  [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family
CSGID 54-499 -83.300 16  IDP06471 gene: E11L; E11L [Monkeypox virus Zaire-96-I-16] NP_536535 [Monkeypox virus Zaire-96-I-16]
H.sapiens 23-283 -78.500 28  sp|O14981|BTAF1_HUMAN TATA-binding protein-associated factor 172 OS=Homo sapiens GN=BTAF1 PE=1 SV=2
196-491 -89.600 24  sp|Q5FWF4|ZRAB3_HUMAN Zinc finger Ran-binding domain-containing protein 3 OS=Homo sapiens GN=ZRANB3 PE=2 SV=2
HGM_OVER 291-433 -3.690 PB046158 _JGI.0336690_ 2004028347 [Human Gut Community Subject 8]
NEW_HUMAN_DOMAINS 202-281 -5.900 15  sp|P57076|CU059_HUMAN Uncharacterized protein C21orf59 OS=Homo sapiens GN=C21orf59 PE=1 SV=1
PDB1018 2-130 -26.300 14  5lzp_1 mol:protein length:180 Bacterial proteasome activator
50-500 -129.000 36  1z63_A mol:protein length:500 Helicase of the snf2/rad54 family
PfamA32U 81-354 -66.600 28  PF00176.23; RAD54_SCHPO/267-575; SNF2 family N-terminal domain
326-500 -41.600 15  PF16203.5; Q0UAJ3_PHANO/498-753; ERCC3/RAD25/XPB C-terminal helicase
SCOP207 66-296 -84.700 39  d1z63a1 c.37.1.19 (A:432-661) Helicase of the SNF2/Rad54 hamily {Sulfolobus solfataricus [TaxId: 2287]}
298-500 -70.100 36  d1z5za1 c.37.1.19 (A:663-906) Helicase of the SNF2/Rad54 hamily {Sulfolobus solfataricus [TaxId: 2287]}
VFDB 1-500 -108.000 33  [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family
19 gi|108885078|ref|NP_072678.2| SNF2 family helicase putative (MG_018) [Mycoplasma genitalium G37] 281 COG1018 1-281 -72.500 34  [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family
CSGID 1-262 -50.600 18  IDP06471 gene: E11L; E11L [Monkeypox virus Zaire-96-I-16] NP_536535 [Monkeypox virus Zaire-96-I-16]
H.sapiens 2-281 -82.700 20  sp|Q9NZC9|SMAL1_HUMAN SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 OS=Homo sapiens GN=SMARCAL1 PE=1 SV=1
HGM_OVER 135-281 -4.130 10  PB014033 A5ZI39_9BACE/1-158 PB014033; Pfam-B_14033;
NEW_HUMAN_DOMAINS 43-281 -5.750 12  sp|Q658Y4|F91A1_HUMAN Protein FAM91A1 OS=Homo sapiens GN=FAM91A1 PE=1 SV=3
PDB1018 27-281 -95.800 34  1z5z_A mol:protein length:271 Helicase of the snf2/rad54 family
PfamA32U 1-104 -18.000 28  PF00176.23; RAD54_SCHPO/267-575; SNF2 family N-terminal domain
76-281 -48.800 14  PF16203.5; Q0UAJ3_PHANO/498-753; ERCC3/RAD25/XPB C-terminal helicase
SCOP207 1-46 -10.400 37  d1z63a1 c.37.1.19 (A:432-661) Helicase of the SNF2/Rad54 hamily {Sulfolobus solfataricus [TaxId: 2287]}
48-281 -90.700 35  d1z5za1 c.37.1.19 (A:663-906) Helicase of the SNF2/Rad54 hamily {Sulfolobus solfataricus [TaxId: 2287]}
VFDB 1-281 -72.500 34  [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family
20 gi|12044869|ref|NP_072679.1| chaperone protein DnaJ (MG_019) [Mycoplasma genitalium G37] 389 COG1018 4-388 -112.000 33  [O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain
CSGID 4-389 -120.000 33  IDP01653 gene: dnaJ; chaperone protein dnaJ [Bacillus anthracis str. `Ames Ancestor`] GBAA4538 [Bacillus anthracis str. `Ames Ancestor`]
H.sapiens 6-377 -102.000 27  sp|Q9UBS4|DJB11_HUMAN(removed signalp:1-22) DnaJ homolog subfamily B member 11 OS=Homo sapiens GN=DNAJB11 PE=1 SV=1
HGM_OVER 143-235 -4.150 HGC00991 gi|163600283|dbj|BABF01000984.1|3.0 TMP01348;
NEW_HUMAN_DOMAINS 135-225 -8.690 14  sp|Q6ZRI0|OTOG_HUMAN Otogelin OS=Homo sapiens GN=OTOG PE=2 SV=3
PDB1018 2-377 -92.000 23  3lz8_A mol:protein length:329 Putative chaperone DnaJ
PfamA32U 7-74 -37.500 52  PF00226.31; Q22028_CAEEL/17-79; DnaJ domain
30-226 -9.660 11  PF05458.12; SIVA_HUMAN/1-175; Cd27 binding protein (Siva)
137-355 -77.900 28  PF01556.18; T0NBZ6_9EURY/129-343; DnaJ C terminal domain
SCOP207 1-87 -43.900 26  d2yuaa1 a.2.3.0 (A:8-93) automated matches {Human (Homo sapiens) [TaxId: 9606]}
151-234 -32.500 31  d1exka_ g.54.1.1 (A:) Cysteine-rich domain of the chaperone protein DnaJ {Escherichia coli [TaxId: 562]}
205-277 -20.800 23  d2q2ga1 b.4.1.0 (A:4-86) automated matches {Cryptosporidium parvum [TaxId: 353152]}
278-372 -28.700 24  d3agxa2 b.4.1.0 (A:246-340) automated matches {Human (Homo sapiens) [TaxId: 9606]}
VFDB 4-388 -112.000 33  [O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain


FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rodrigues AP, Grant BJ, Godzik A, Friedberg I. The 2006 automated function prediction meeting. BMC Bioinformatics. 2007 May 22;8 Suppl 4:S1-4.