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# Query Length Result vs. Range Score %id Covered by template(s)
1 gi|6319249|ref|NP_009332.1|(removed signalp:1-20) hypothetical protein; Pau8p (YAL068C) [Saccharomyces cerevisiae] 100 PfamA32U 2-95 -43.900 23  PF00660.17; E7KHT3_YEASA/13-116; Seripauperin and TIP1 family
2 gi|33438754|ref|NP_878038.1| Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; Yal067w-ap (YAL067W-A) [Saccharomyces cerevisiae] 75 PfamA32U 22-64 -6.960 32  PF05432.11; D2GX57_AILME/17-317; Bone sialoprotein II (BSP-II)
3 gi|6319250|ref|NP_009333.1| Putative permease, member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide; Seo1p (YAL067C) [Saccharomyces cerevisiae] 593 PfamA32U 96-593 -19.700 PF06609.13; Q8NII4_FUSAU/1-598; Fungal trichothecene efflux pump (TRI12)
131-564 -20.800 11  PF00083.24; STP1_ARATH/26-489; Sugar (and other) transporter
146-548 -26.400 PF06779.14; Q8Y185_RALSO/36-399; Uncharacterised MFS-type transporter YbfB
4 gi|6319252|ref|NP_009335.1| Putative protein of unknown function; has homology to FLO1; possible pseudogene; (YAL065C) [Saccharomyces cerevisiae] 128 PfamA32U 89-126 -6.990 36  PF07666.11; Q8EWG6_MYCPE/16-144; M penetrans paralogue family 26
5 gi|6319253|ref|NP_009336.1| Fungal-specific protein of unknown function; Yal064w-bp (YAL064W-B) [Saccharomyces cerevisiae] 126 PfamA32U 13-78 -7.580 35  PF17608.2; Q74KI2_LACJO/1-124; Family of unknown function (DUF5504 topsan)
6 gi|7839146|ref|NP_058136.1| Putative protein of unknown function; YAL064C-A is not an essential gene; Yal064c-ap (YAL064C-A) [Saccharomyces cerevisiae] 126 PfamA32U 1-98 -44.300 30  PF10528.9; B4UN21_CANGA/106-200; GLEYA domain
7 gi|6319254|ref|NP_009337.1| Protein of unknown function; may interact with ribosomes, based on co-purification experiments; (YAL064W) [Saccharomyces cerevisiae] 108 PfamA32U 15-82 -6.810 16  PF01822.19; A7ERH4_SCLS1/37-114; WSC domain
8 gi|33438755|ref|NP_878039.1| Putative protein of unknown function; identified by expression profiling and mass spectrometry; Yal063c-ap (YAL063C-A) [Saccharomyces cerevisiae] 96 PfamA32U 31-94 -6.790 25  PF13798.6; X2GN24_9BACI/8-168; Protein of unknown function with PCYCGC motif
9 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] 500 PfamA32U 4-216 -9.730 11  PF07691.12; Q7SG54_NEUCR/449-597; PA14 domain
112-213 -24.800 34  PF10528.9; B4UN21_CANGA/106-200; GLEYA domain
242-500 -13.900 PF08549.10; E3Q6J3_COLGM/3-717; Fungal domain of unknown function (DUF1750 topsan)
10 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] 500 PfamA32U 1-500 -11.800 11  PF06070.11; PP150_HCMVM/1-1048; Herpesvirus large structural phosphoprotein UL32
114-500 -13.300 PF17076.5; SBE22_CANGA/1-813; SBE2, cell-wall formation
11 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] 500 PfamA32U 1-500 -11.600 12  PF06070.11; PP150_HCMVM/1-1048; Herpesvirus large structural phosphoprotein UL32
61-496 -13.200 12  PF17076.5; SBE22_CANGA/1-813; SBE2, cell-wall formation
12 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] 500 PfamA32U 1-453 -13.200 PF17076.5; SBE22_CANGA/1-813; SBE2, cell-wall formation
412-500 -12.100 PF05466.12; F6R3X8_HORSE/2-233; Brain acid soluble protein 1 (BASP1 protein)
13 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] 298 PfamA32U 19-284 -15.600 PF17076.5; SBE22_CANGA/1-813; SBE2, cell-wall formation
14 gi|6319256|ref|NP_009339.1| NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources; Gdh3p (YAL062W) [Saccharomyces cerevisiae] 457 PfamA32U 3-454 -22.600 13  PF05088.12; A4XWG7_PSEMY/77-1608; Bacterial NAD-glutamate dehydrogenase
40-168 -73.700 31  PF02812.18; R6WCN3_9CLOT/34-162; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
185-454 -72.400 32  PF00208.21; DHE3_ORYSJ/176-408; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
15 gi|6319257|ref|NP_009340.1| Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3; BDH2 is an essential gene; Bdh2p (YAL061W) [Saccharomyces cerevisiae] 417 PfamA32U 26-159 -44.900 35  PF08240.12; A9CHB7_AGRFC/24-130; Alcohol dehydrogenase GroES-like domain
144-417 -10.300 11  PF08704.10; Q6DFS3_XENTR/64-300; tRNA methyltransferase complex GCD14 subunit
167-387 -40.800 18  PF16912.5; I7BJ28_NATSJ/144-370; Glucose dehydrogenase C-terminus
16 gi|6319258|ref|NP_009341.1| NAD-dependent (R,R)-butanediol dehydrogenase, catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source; Bdh1p (YAL060W) [Saccharomyces cerevisiae] 382 PfamA32U 26-159 -46.200 32  PF08240.12; A9CHB7_AGRFC/24-130; Alcohol dehydrogenase GroES-like domain
167-382 -42.000 19  PF16912.5; I7BJ28_NATSJ/144-370; Glucose dehydrogenase C-terminus
17 gi|6319259|ref|NP_009342.1| Protein of unknown function, localized in the nucleoplasm and the nucleolus, genetically interacts with MTR2 in 60S ribosomal protein subunit export; Ecm1p (YAL059W) [Saccharomyces cerevisiae] 212 PfamA32U 31-152 -61.400 52  PF09135.11; Q6CLT8_KLULA/8-125; Alb1
18 gi|6319260|ref|NP_009343.1|(removed signalp:1-19) Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast; Cne1p (YAL058W) [Saccharomyces cerevisiae] 483 PfamA32U 14-394 -125.000 32  PF00262.18; R4XC34_TAPDE/40-408; Calreticulin family
19 gi|41629666|ref|NP_009345.2| Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; homolog of Gpb1p; Gpb2p (YAL056W) [Saccharomyces cerevisiae] 880 PfamA32U 258-851 -34.400 11  PF03089.14; F6YI02_MONDO/51-390; Recombination activating protein 2
20 gi|6319263|ref|NP_009346.1| Putative peroxisomal membrane protein required for import of peroxisomal proteins, functionally complements a Pichia pastoris pex22 mutation; Pex22p (YAL055W) [Saccharomyces cerevisiae] 180 PfamA32U 51-167 -55.300 22  PF12827.7; C4Y073_CLAL4/43-162; Peroxisomal biogenesis protein family


FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rodrigues AP, Grant BJ, Godzik A, Friedberg I. The 2006 automated function prediction meeting. BMC Bioinformatics. 2007 May 22;8 Suppl 4:S1-4.