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Query: gi|30260200|ref|NP_842577.1| DNA gyrase subunit B (BA_0005) [Bacillus anthracis str. Ames], from B.anthracis

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MEQKQMQENSYDESQIQVLEGLEAVRKRPGMYIGSTSGKGLHHLVWEIVDNSIDEALAGYCDEINVSIEEDNSIRVTDNGRGIPVGIQEKMGRPAVEVIMTVLHAGGKFGGGGYKVSGGLHGVGASVVNALSTELEVFVHREGKIHYQKYERGIPVADLKVIGDTDQTGTITRFKPDPEIFQETTVYEFDTLATRMRELAFLNRNIKLTIEDKREHKQKKEFHYEGGIKSYVEHLNRSKQPIHEEPVYVEGSKDGIQVEVSLQYNEGYTNNIYSFTNNIHTYEGGTHEVGFKTALTRVINDYGRKNSILKDADSNLTGEDVREGLTAIVSIKHPNPQFEGQTKTKLGNSEARTITESVFSEAFEKFLLENPNVARKIVEKGTMAARARVAAKKARELTRRKSALEVSSLPGKLADCSSKDPAISEIYIVEGDSAGGSAKQGRDRHFQAILPLKGKIINVEKARLDKILSNDEVRTIITAIGTNIGGDFDIEKARYHKVIIMTDADVDGAHIRTLLLTFFYRYMRQIIEHGYIYIAQPPLFKVQQGKKIQYAYNEKELEKILAELPAQPKPGIQRYKGLGEMNPTQLWETTMDPEVRSLLQVSLQDAIEADETFEILMGDKVEPRRNFIQENAKYVKNLDILast
1 -97.700sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3  ali   23  4.........................................................................................................................................................................................................................................................................SEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKK---NKGGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQPKSFGSTCQLSEKFIKAAIGCGIVESILNW----VKFKAQVQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS.............................................................................. 300
2 -92.200sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3  ali   24  12...........................................................................................................................................................................................................................................................ELANERWDVCLTLSEKG-FQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKK---NKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILNW----VKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVK................................................................................................... 300
3 -84.300sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3  ali   24  2...............................................................................................................................................................................................................................................................................................................................................................................................................KYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPED-DAAITLAFSKKKIDDRKEWLTNFMEDRRQRRL 248
4 -82.800sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3  ali   25  1...................................................................................................................................................................................................................................................................................................................................................................................................................................NSTECTLILTEGDSAKTLAVSGLGRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSSTPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRH-RIQFKYSGPEDDAAISLAFSKKQIDDRKEWLTNFMEDRRQRKL 227
5 -77.800sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3  ali   19  1.......................................................................................HKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKL-DKDIVALMTRRAYDLAGSCRGVKVMFNGK-----KLPVNGFRSYVDLYVKDKLDETGVALKVIHELANERWDVCL-TLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKK---NKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCG-----IVESILNWVKFKAQTQLNKKCSS................................................................................................................................................................................................................................................. 300
6 -71.700sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3  ali   19  1............................................................................................................YDDDEKKVTGGRNGYGAKLCNIFSTKFTVETREYKKMFKQTWMDNMGRAGEMELKPNGEDYTCITFQPDLSKFKMQSLDKDALMVRRAYDIAGSTKDVKVFLNGNKLPVK--------GFRSYVDMYLKDKLDETGNSLKVIHEQVNHRWEVCLTMSEKG-FQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKK---NKGGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQPKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQVQLNKKCSAV----KHNRIKGIPKLDDANDAGGR............................................................................................................................................................................................................................. 300
7 -71.500sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3  ali   21  20.KNEDAKKRLSVERIYQKKTQLEHILLRPDTYIGSTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQTWMDNMGRAGEMPFNGEDYTCITFQPDLSKFKMQSLDKDALMVRRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNSLKVIHEQV.......................................................................................................................................................................................................................................................................................................................................................................................................... 293
8 -69.100sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3  ali   23  40ANKNDSSKKLSVERVYQKKTQLEHILLRPDTYIGSVEVPGLYKIFDEILVNAADNKQRDKNMTCIKVSPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETACKKHSFKQTWMNNMMKTSEAKIKHDGEDYTCITFQPDLSKFKMEKLDKDALMTRRAYDLAGSCRGVKVMFNGKK--------LPVNGFRSYVDLYVKDK................................................................................................................................................................................................................................................................................................................................................................................................................. 299
9 -16.200sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3  ali   18  1.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ASKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRFRYAGPEDDAAITLAFS---KKKIDDRKEWLTNFMED...... 92
10 -13.800sp|Q9Y6X9|MORC2_HUMAN MORC family CW-type zinc finger protein 2 OS=Homo sapiens GN=MORC2 PE=1 SV=2  ali   17  1MAFTNYSSLNRAQLTFEYLHTN------------STTHEFLFGALAELVDNARDAD----ATRIDIYAERREDLCFLDDGAGM-----------DPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMIGKDFILFTKKEDT................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 124
11 -13.600sp|Q86VD1|MORC1_HUMAN MORC family CW-type zinc finger protein 1 OS=Homo sapiens GN=MORC1 PE=2 SV=2  ali   15  3................DRYPALQRAQLRLD-FIHANSTTHLFGALAELLDNARDAG----AERLDVFSQGGFMLCFLDDGCGM-----------SPEEASDIIYFGRSKKRLSTLKFIGQYGNGLKSGSMIGKDFILFTKKEETMTCVFFS......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 130
12 -12.800sp|Q9UHC1|MLH3_HUMAN DNA mismatch repair protein Mlh3 OS=Homo sapiens GN=MLH3 PE=1 SV=3  ali   15  2...............IKCLSVEVQAKLRSGLAISSLG-----QCVEELALNSIDAE----AKCVAVRVNMETQVQVIDNGFGMGSD---------VEKVGNRYFTSHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMFVKLFQSGKALKACEADVTRASAGTTVTVYPVRRKCMDPRL-EFEKVRQRIEALSLMHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYISSEAHYNKNMQFL-FVNKRLVLR---------TKLHKLIDFLLRKESIICKPKNGPTSRQMNSS............................................................................................................................................................................................................................................................................................................................ 293
13 -12.600sp|A6NHR9|SMHD1_HUMAN Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens GN=SMCHD1 PE=1 SV=2  ali   13  100LQSVNQLLLTATKERIDFLPHYDTLVKSG-EYYASEGQNPLPFALAELIDNSLSATSRN-VRRIQIKLQGKPAVAVIDNGRGM-----------TSKQLNNWAVYRLSKFTRQGDFESSYFGVGGKQAVFVGQSARMISKPADS................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 259
14 -12.300sp|P40692|MLH1_HUMAN DNA mismatch repair protein Mlh1 OS=Homo sapiens GN=MLH1 PE=1 SV=1  ali   13  1MSFVAGVIRRLDETVVNRIAAGE-VIQRPA------------NAIKEMIENCLDAK----STSIQVIVKEGGLIQIQDNGTGIRKE---------LDIVCERFTTSQSFEDLASISTYGFRGEALASISHVAHTITTKTADGKCAYRASYSDGKLKAPPKPCAGNQGTQITVE-IATRRKALKNPSEEYGKILEVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDKTLAFKMNISNANYSVKKCIFLLFINH.......................................................................................................................................................................................................................................................................................................................................................................... 264
15 -12.200sp|Q8TE76|MORC4_HUMAN MORC family CW-type zinc finger protein 4 OS=Homo sapiens GN=MORC4 PE=1 SV=2  ali   16  10.GPGAPGCGLARPGGGPQAFGIRLSTMSPR-YLQSNSSSHPFSAIAELLDNAVDPD----VSARTVFIDVEEVLTFTDDGCGM-----------TPHKLHRMLSFGFTDKVIKKSQCPGVFGNGFKSGSMLGKDALVFTKNGGTLTVGLLS......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 152
16 -11.900sp|Q14149|MORC3_HUMAN MORC family CW-type zinc finger protein 3 OS=Homo sapiens GN=MORC3 PE=1 SV=3  ali   20  1MAAQPPRGIRLSALCPKFLHTN------------STSHTWPFSAVAELIDNAYDPD----VNAKQIWIDKTVILTFTDNGNGM-----------TSDKLHKMLSFGFSDKVTMNGHVPGLYGNGFKSGSMLGKDAIVFTKNGES................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 124
17 -11.700sp|P54278|PMS2_HUMAN Mismatch repair endonuclease PMS2 OS=Homo sapiens GN=PMS2 PE=1 SV=2  ali   15  2..ERAESSSTEPAKAIKPIDRKSVHQICSGQVV-----LSLSTAVKELVENSLDAG----ATNIDLKLKDYGLIEVSDNGCGVEEE---------FEGLTLKHHTSQEFADLTQVETFGFRGEALSSLCALSD-VTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQ--HKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGS................................................................................................................................................................................................................................................................................................................................................................................................................... 229
18 -11.600sp|P03950|ANGI_HUMAN(removed signalp:1-24) Angiogenin OS=Homo sapiens GN=ANG PE=1 SV=1  ali follow..  17  1................QDNSRYTHFLTQ---HYDAKPQGRDDRYCESIMRR---RGLTSPCKDINTFIHGRSIKAICENKNGNPHRENLRISKSSFQVTTCKLHGGSPWPPCQYRATAGFRNVVVACENGLPVHLDQSIFR................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 121
19 -10.500sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3  ali   16  1..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRFKYSGPEDDAAISLAFS---KKQIDDRKEWLTNFMEDRR.... 73
20 -10.300sp|O95744|PM2L2_HUMAN Putative postmeiotic segregation increased 2-like protein 2 OS=Homo sapiens GN=PMS2L2 PE=5 SV=1  ali follow..  16  64..PVQPAKLTEPAKAIKPIDRKSVHQICSGPVV-----LSLSTAVKKIVGNSLDAG----ATNIDLKLKDYGLIEVSGNGCGVEEENFEGLSLSALKHHTSKI---REFADLTRVETFGFQGKALSSLCALSD-VTISTCHVSAKVGTRLVFDHDGKIIKKTPYPHPRGTTVSVK---QLFSTLPVRHKEFQRNIKKKRACFPFAFC................................................................................................................................................................................................................................................................................................................................................................................................................................................. 254
21 -10.200sp|P54277|PMS1_HUMAN PMS1 protein homolog 1 OS=Homo sapiens GN=PMS1 PE=1 SV=1  ali   14  1...............MKQLPAATVRLLSSSQIITSVVS-----VVKELIENSLDAG----ATSVDVKLENYGKIEVRDNGEGIKAV---------APVMAMKYYTSNSHEDLENLTTYGFRGEALGSICCIAE-VLITTRTAADNFSTQYVLDGSGHILSQKPSHLGQGTTVTALPVRKQFAKKCKDEIKKIQDLLMSFGILKPDLRIVFVHN........................................................................................................................................................................................................................................................................................................................................................................................................................................... 193
22 -10.100sp|O95746|PM2LG_HUMAN Postmeiotic segregation increased 2-like protein 16 OS=Homo sapiens GN=PMS2L16 PE=2 SV=1  ali follow..  29  37...........................................AVKKIVGNSLDAG----ATNIDLKLKDYGLIEVSGNGCGVEEE.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 77
23 -10.100sp|Q13400|PM2L8_HUMAN Postmeiotic segregation increased 2-like protein 8 OS=Homo sapiens GN=PMS2L8 PE=3 SV=1  ali follow..  13  149.LERAENSSTEPAKAIKPIDRKSVHQICSGPVVPSLRPN----AVKELVENSLDAG----ATNVDLKLKDYGLIEVSGNGCGVEEE---------FEGFTLKHHTCQEFADLTQVETFGFRGEALSSLCALSD-VTISTCRVSAKVGTRLVFDHYGKIIQKTPYPRPRGMTVSVKPVHHKEFQRNIKKKRACFPFAFCRDCQFPEASPAM.............................................................................................................................................................................................................................................................................................................................................................................................................................................. 350
24 -9.650sp|Q15118|PDK1_HUMAN [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial OS=Homo sapiens GN=PDK1 PE=1 SV=1  ali follow..  15  273........................................LYHMVFELFKNAMRATMEHHANRIQVHVTLGNTVKMSDRGGGVPLRKIDR--------LFNYMYSRPRVETSRAVPLAGF-GYGLPISRLYAQYF......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 369
25 -9.620sp|Q16654|PDK4_HUMAN [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial OS=Homo sapiens GN=PDK4 PE=1 SV=1  ali follow..  15  248........................................LHHMLFELFKNAMRATVEHQENQIEVIVVLGKTIKISDRGGGVPLR--------IIDRLFSYTYSTAVMDNSRNAPLAGF-GYGLPISRLYAKYF......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 344
26 -9.600sp|Q13670|PM2LB_HUMAN Putative postmeiotic segregation increased 2-like protein 11 OS=Homo sapiens GN=PMS2L11 PE=5 SV=1  ali follow..  15  143CNAPLPGPGPYRTEPAKAIKPIDRKSVHQ-ICSGPV-VLSLSTAVKELVENSLDAG----ATNIDLKLKDYGMIEVSGNGCGV-----EEENFEGLMMSPFL-PATSRRRLGL-----DWCLITMGKSSRRP............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 259
27 -9.310sp|Q15120|PDK3_HUMAN [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial OS=Homo sapiens GN=PDK3 PE=1 SV=1  ali follow..  16  241........................................LFHMLFELFKNSMRATVELYEDRVKTLVTLGKSIKISDLGGGVPLR--------KIDRLFNYMYSTAP-EPTRAAPLAGF-GYGLPISRLYARYF......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 338
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 5 1 8   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Lukasz Jaroszewski, Zhanwen Li, S. Sri Krishna, Constantina Bakolitsa, John Wooley, Ashley M. Deacon, Ian A. Wilson, Adam Godzik, Exploration of Uncharted Regions of the Protein Universe. Plos Biology. 2009 Sep. 7(9):e1000205