current user: public
If you have questions about the server, please let us know.

Query: gi|30260213|ref|NP_842590.1| DNA polymerase III subunits gamma and tau (BA_0019) [Bacillus anthracis str. Ames], from B.anthracis

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470    .  480    .  490    .  500    .  510    .  520    .  530    .  540    .  550    .  560
# Score Template Links and tools%idFirst MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDERVTTEDVLAVTGSVSQQYLGNLVECIRENDVSRALRIIDEMMGKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVMVDEQFRMLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGADRLQAIMNRMQQLEKELEQVKKNGVPVGVQQEVKETRAAPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKAYNKVAFAVLLENSEPVAASDDTYVLAFQYEIHCKMASENREAMDTVEQALFELLSKKLNMIAIPKSEWGKIREDFLKREGGSSEESPEKKEDPLIEEAIKLVGQELIEIKELast
1 -65.900PF13177.6; A5VIC8_LACRD/13-171; DNA polymerase III, delta subunit  ali follow..  32  1....................QPAIITRFQKILSNNELAHAYLFVGPGGSGKMSIAQWLSLRLFCLHPQDNEPDLTCAECQRILSGNHPDIVYAAPEGRQKVDEIRRLKAEFSKSAVEGNKKIFIIKDADKMTNGAANSLLKFIEEPGAGVYIFMLTTNKSAVLPTIRSRTQVIELPPL................................................................................................................................................................................................................................................................................................................................................................................................ 159
2 -40.200PF05496.12; RUVB_BACAN/21-179; Holliday junction DNA helicase RuvB P-loop domain  ali follow..  19  1.........LRPQTLRQYIGQDKAKHNLEVFIEAAKMREETLLYGPPGLGKTTLANIIANEMGVNVRTTSGPAIERPGDLAA------VLTSLQPGDVLFIDEIHRLHRSIELYPAMEDFCLDIVIGKGPSA--------RSVRLDLPPFTLVGATTRAGALSAPLRDRFGVLS.................................................................................................................................................................................................................................................................................................................................................................................................... 157
3 -32.900PF05673.13; Q0K6N5_CUPNH/29-287; Protein of unknown function (DUF815 topsan)  ali follow..  14  19.GYLQPVRQLPPIHLDDLKNIERQKDAIVANTRSKLPANNVLLTGARGTGKSSLIKACLNAFVRDG---------------------LRLVEVD---KDDLGDLGDIVELVAQRPE--RFVIFCDDLSFEEGESGYKSLKSALDAQSDNVLIYATSNRRHLLPEYMKDNETHTDDGEIHPGEVVEEKISLSERFGLWLS-AIVGHWLRHFGCTDEDIAAARGDALVWASGRVAWQFARDWGG................................................................................................................................................................................................................................................................................................................................ 257
4 -24.800PF12169.8; Q11B01_CHESB/247-389; DNA polymerase III subunits gamma and tau domain III  ali follow..  18  1.......................................................................................................................................................................................................................................VTAETVRDMLGLADRARVIDLFEHLMKGDVAAALAEYRAQYDAGADPAAVLTDLAEFNHLVTRMRFVPDANDGSLPQEERTRGLEFSKNLSVRVLSRTWQMLLKGIQEVQGSSRPISAGEMVLIRIAHAANLPTLDEALKT.............................................................................................................................................................................................. 142
5 -16.300PF03215.15; RAD24_YEAST/58-237; Rad17 P-loop domain  ali follow..  17  10......YEKFKPNCLEQVAIHKDVQEALDAMFLPNAKHRILLLSGPSGCSKSTVIKELSKILVPKYRQNSNG-----------TSFRSTPNEHKVTEFRGDCIVNDLPQMESFSEVMSNLSLILIEDLNVFHIDTRRRFQQLILQ-------WLYSSEPLLPPLVIC........................................................................................................................................................................................................................................................................................................................................................................................................... 165
6 -12.800PF17864.1; RUVB_ALKMQ/186-259; RuvB AAA lid domain  ali follow..  15  2..................................................................................................................................................................................NNKQLTAIVKRSARILDAYIDDEGATEIASRSRGTPRIANRLLRRVRDYADGRITKRVAEEALILLEVD........................................................................................................................................................................................................................................................................................................................... 74
7 -12.100PF00004.29; LON_BRECH/351-493; ATPase family associated with various cellular activities (AAA)  ali follow..  23  2.........................................CLVGPPGVGKTSLARSVARALG-------------REFVRISLGGVRDEAEIRGHRRTYVGAL-RIIQGMKQAGTIN--PVFLLDEIDKLASDPASALLEVLDPNQTNVMFITTANSLDTIPRPLLDRMEVISI................................................................................................................................................................................................................................................................................................................................................................................................... 140
8 -12.000PF07724.14; Q7PAG5_RICSI/595-759; AAA domain (Cdc48 subfamily)  ali follow..  21  5.......................................SFLFLGPTGVGKTELTKALAGFL-----------DDRNAILRIDMSEYMEKHAISRLIGAGYDQGGVLTEAVRRRP----YQVILFDEVEKAHPDIFNIMLQILDE--KNTIIVLTS----NLGAEILVNQKEDEDTYKVKDEVMEYVKAVFKPEFLN............................................................................................................................................................................................................................................................................................................................................................................. 160
9 -11.400PF01637.18; A8M939_CALMQ/15-228; ATPase domain predominantly from Archaea  ali follow..  11  1..............F---TDREVAIRQIEKLAEKGT-WNPVVIYGPEGCGKSAFLKQAVEVLSPLEDESNEKLRYSEELRGLFRDIMTRIPTPFNDASALIDIAISLLYDVVRRRIRRKI-ALLADDVFAIGLDKAELLVKRLLN--YERIVVIVATSEGVTWGRIGRHAEIMAMWNMPREGFGKLYNALPGPK------PPFEEVWRWTGGN---ALEML..................................................................................................................................................................................................................................................................................................................................................... 214
10 -11.200PF01078.21; Q8EJV7_SHEON/193-396; Magnesium chelatase, subunit ChlI  ali follow..  17  1.............CLSEVIGQYQAKQALEIAAAGN---HNLLMLGPPGTGKTMLASRMMALLPALNYEEALEVAAIHSVAGINIKPQDFLKRPFRAPHHTCSSISLVGGGSIPKPSLAHRGVLFLDEVAEFPRKVLDCLREPMET-LSRFQLIAAMNP---------SPSGDID-------------------GPNRATPDQIQRYLARLSGPFIDRFDLTIEVPKLPAGTL.......................................................................................................................................................................................................................................................................................................................................... 204
11 -11.100PF00308.18; DNAA_STRCO/317-535; Bacterial dnaA protein  ali follow..  14  1.....LNPKYLFDTF--VIGASN-AAAVAVAEAPAKAYNPLFIYGESGLGKTHLLHAIGHYA-----------------RSLYPGTRVRYVSSEEFTNEFINSIRD-GKGDSFRKRYREMDILLVDDIQFLADHTFNTLVLSSDRPPKQL---------VTLEDRLRNRFEWGLITDVQPPELETRIAILAVQEQLNAPPEVLEFIASRISRNIRELEGALIRVTAFAS............................................................................................................................................................................................................................................................................................................................................. 217
12 -11.000PF06144.13; Q8E0E6_STRA5/20-192; DNA polymerase III, delta subunit  ali follow..  11  1.........................................VLAGEDLGQYAQMKEKLFQVIG-------------------FNKDDLAYSYFDLSE----EDYQNAELDLESLPFLSDYKVVIFDQFQDITTDKMKRFEAYLQNPVDTTRLVICAPGKRRLVKLLKRDARVLEANTLKESDLKTYFQKYAHQEGLVFEAGVFDELLIKSNYDFSDTLTNIAFL.................................................................................................................................................................................................................................................................................................................................................. 172
13 -10.600PF03266.15; NTPTH_METAC/3-167; NTPase  ali follow..  11  2........................................IAVTGSPGVGKSTVVAKTAEKLAEKPGFKIG---RTAEIRKEGHREGFSIRDLATGKTGILSHVKGSGPRANAVRNALACDLVVIDEIGPMESQSFVSAVEEVLESDKPVLAVLHHSSRHPLAQRFRKGFEVLTVDKGNRDELPEKI....................................................................................................................................................................................................................................................................................................................................................................................... 164
14 -10.300PF07726.11; Q87G66_VIBPA/36-166; ATPase family associated with various cellular activities (AAA)  ali follow..  19  3.........................................LVEGPPGLAKTRAVKSLSDCVEGDHRIQFTP----------------DLLPAD----TGTDIFRPETGEFTFQSGPIFNSLILADEINRAPAKVQAAMLEAMAEALPELFLVMATQNPYPLPEAQLDR......................................................................................................................................................................................................................................................................................................................................................................................................... 128
15 -10.200PF02689.14; HELI_EHV2/2-789; Helicase  ali follow..  15  1.......EEPGAGFILNMTSDSKVRAIVGRGLAAKTVPSTFLITGTAGAGKSTSISALYQSLNCL--ITGATAVAAQNLSNGLKTYCPTIYSAFGFKSRHINDMEGINELCKYTPTLWTTNIIVIDEAHILTAVVFNSWLQT----PLYVVCVGSPTQTDAIQSTYNHSMQKHHIQE-CDNILTFLMKHEAVSRYVDLNHNWALFIKRCTDPEFGHLLKTLEYNLDISPRMVDYID...................................................................................................................................................................................................................................................................................................................................... 315
16 -9.990PF18748.1; A0A0A0YSQ1_9CAUD/11-206; P-loop Nucleotide Kinase1  ali follow..  12  3.......................LMKPKPVQTRYPARGELFYVKACNGAGKSTIPSYCAERDPEAYTVSQD--------YGMLAFGKYDKSKSKGVDSLKDYDEMKKAVELSELEEFIGYTA-FFEGV--IPSTILHTWVEYLNRPARPLTTVFIDTDLETCLSRVNSRNGGAEFNADLVTEKFNRVMSHKTRHK--------ELFPSVPAVTIRSQGITIDEMVS................................................................................................................................................................................................................................................................................................................................................ 196
17 -9.770PF12170.8; F0LND5_VIBFN/559-697; DNA polymerase III tau subunit V interacting with alpha  ali follow..  16  1..................................................................................................................................................................................................................................................................................................................................................................................................................................ALEHEKTPEMTAKLIHEAIELDEWANIVQRLHTAK--LVEQLALNSTYKK-SGASIELTLRPS---HAHLNTDKAQSELLQALNDQLQEDCHLSVTIGDDGETPLERERLYQGKLSQAIDHLVADPTVQFIERRFSAELDK... 136
18 -9.690PF06309.11; O45271_CAEEL/5-130; Torsin  ali follow..  14  24...............RFIYGQHLVIDTVVRSIKHPQKPLVLSFHGGPGTGKNYVTEIIAKNT-------------------FRSGLQSPYVKYFVATKKHIEDYKLLKEQLIQSADGCDRSIFVF..................................................................................................................................................................................................................................................................................................................................................................................................................................................... 126
19 -9.660PF07652.14; Q32ZD8_9FLAV/1675-1822; Flavivirus DEAD domain  ali follow..  12  1...............................FKKKQLI---VLDPHPGAGKTRLPEFIRQAVEALAPTRVVAAEMAEALNGLPVRYLTPAVIQQHTGKEIVDLMCHFTMRLLSGGRVPNYNMFIMDEAHFTDPSSRGYISTKVDMGEASAVFMTATPPGSREP............................................................................................................................................................................................................................................................................................................................................................................................................... 142
20 -9.340PF05621.11; B7J739_ACIF2/21-211; Bacterial TniB protein  ali follow..  16  17.....................NRLLDNLRSLMEKPVRPRMLLIVGDSNNGKTTVIRRFQKLHG----------------GVNEDAEPVPVIVSEAPPSADEKGLSKLRYQVVHLMRDCHVRILVIDEFHSLLTGTVTKAIKLLCNELAIPIVGVGIREAVRVLHTDPQHASRFDVVTLPPWEL........................................................................................................................................................................................................................................................................................................................................................................................... 189
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 8   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.