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Query: gi|30260209|ref|NP_842586.1| deoxynucleoside kinase family protein (BA_0015) [Bacillus anthracis str. Ames], from B.anthracis

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWSFQTEMFFLCNRYKQLEDINIKYLNQRKPVVADYHIFKNVIFASRTLKDSQYDKYMQIYRILTQDMPVPNVIVYLTASLETLQRRIAMRGREFEKNMDPNYLLQLTKDYETAMDAFKKDHPDIPVLKFNGDDMDFVKNPDDLNVILSALQNTLLKESKLast
1 -72.100[F] COG1428 Deoxynucleoside kinases  ali follow..  23  4.VGNKVIVLAGMIGAGKSSYTELIANELGTKAFYESIKDNRILEMFYDDPKRWAFALQIYFLNTRFRSIKAALTDQNNVLDRSIYEDALFTQINFEEGNISEPEMDTYLDLLDNMMEELKAPDLLIYLRGSLDTVLSRISLRGRPYEQTFDLDYYKHLHSRYDSWFESY----DKSDTLVINIDEVDI-NKPSDAKYVMQLIHEKLKR... 214
2 -58.500[C] KOG3877 NADH:ubiquinone oxidoreductase, NDUFA10/42kDa subunit  ali follow..  17  80.ENSKVICVEGPIAAGKSKFAKELAEELDMEYYPAVDLDLIYVRNFCLDPHDLAAQFQIRMYMLRYSQYIDALQHVLSTGQGVVLERSPYSDFVFMEGYLSRGARSVYNELRQNTIGELLKPHLVIYLDLPVDAVKKQIKARNVDYEKVFSDAYLSDLEQLYKQQYLKDIS--THAELLIYDWTA------GGETEVVVEDIERIDFNQFE 313
3 -40.600[F] COG0125 Thymidylate kinase  ali follow..  18  2..SGLFITFEGPEGAGKTTVLQEIKNILTAEGLQVMATREPGGIDIAEQIRE-PKTEALLYAAARRQHLVEKVKPALEQGFIVLCDRFIDSPLAYQGYARGLGIDEV--LSINEFAIGDMMPHVTVYFSIDPEEGLKRIYANGSREKNRLDLDFHTKVQEGYQELMKRFPE-----RFHSVDAGQ----SKDLVVQDVLKVIDEALKKIQ. 211
4 -28.800[F] KOG3327 Thymidylate kinase/adenylate kinase  ali follow..  15  6...............RSSSIGQVINSYLT------------------NSKDLPDEVIHLMFSANRWEHINQVK-EKLLEGTTLVVDRYSFSGVAYSAAK------GLDFDWCYAPERGLIKPDAVFYLRAPPNDLTHRGQYGKERYEK---VEFQGRVAEVFNRICSK-----EGSYFHQFDARQ----SVEDLHAQIASITEELLPKVAT 164
5 -24.900[F] COG2019 Archaeal adenylate kinase  ali follow..  1....MRSVITGVAGVGKTTVLDIVARESGIPVVN---YGTLMFEVAKRRGLVENRDQIRKLSRETQVDLQKLAGEEIGKMENAIVDTHM--SIKTPFGYLPGLPEWVLRSI---------NASVFVIIEADPAIIKRRRDNDPTRARDDEGVDSIREHQEMNRYFAAAYSIFS-GATVKIVKNEE-------GKPEQAADEIVRVIK.... 181
6 -24.400[R] COG0645 Predicted kinase  ali follow..  16  3.....LAVTHGVSAVGKSQVAMRLVEALGAVRLRSDIERKR-LFGEQPEHDRGQFAAGIYSSQASYAHLHQLAAKILQAGYPVVIDAAYLKQN--------------QRQAACHIAEETGVPFLILDCQAPEAVIAGWLAQRQAEGKSDATLDVIRTQQATREPLTAA-----ETVQSKRVDTHD------AASLDGLVDGIRQRLPGL.. 185
7 -23.600[V] COG3896 Chloramphenicol 3-O-phosphotransferase  ali follow..  15  20MPEGKLILLNGGSSAGKTSLALAFQDLAAECWMHIGIDL----SAVEADGLEWFTVHPGPILDLAMHSRYRAIRAYLDNGMNVIADDVIWTREWLVDALRVFEGCRVW----------------MVGVHVSDEEGARRELERGDRHPGWNRGSA-RAAHADAE---------------FELDTTATP--------HELARELHESYQACPY 212
8 -22.600[F] KOG3347 Predicted nucleotide kinase/nuclear protein involved oxidative stress response  ali follow..  19  1MLLPN-ILLTGTPGVGKTTLGKELASKSGLKYINGDLAREEQLYDGYDEEYDCPILDEDRVVDELDNQMRE---------GGVIVDYHGCDFFPERWF------------------------HIVFVLRTDTNVLYERLETRGYNEKKLTDNIQCEIFQVLYEEATASYKEE------IVHQLPSNKPEELENNVDQILKWIEQWIKDHNS 172
9 -22.500[F] COG1936 Predicted nucleotide kinase (related to CMP and AMP kinases)  ali follow..  16  3......IAITGTPGVGKTTVAKLLAKKLNYEYVS--------LKDFALEKGCGRRVNDEV--EVEIDELAYFIERELKGKNAVLDGH----------------------------LSHLMPVDLVVVLRAHPKLIGERLRERGYDREKIGENVEAELVDAVLIEAIEEHE------NVIEVDTTNKS--------EDVVEEIVSLINSGIK 156
10 -22.000[G] COG2074 2-phosphoglycerate kinase  ali follow..  10  88CKEPLIILIGGASGVGTSSIAFEVANRLGIRNMISTDMIREVMRKIVSRELLPSIYESSYTAYQSLRIPPPPELDEVLIGFRDHVESVSIGVEAVIERALTEGISIVIEGFIREDLVNKENVAMFVLTVSDENVHKGRFYSRCRQMWARRPLKRYISYFWAIRRIHRYIENQARKHGVPVIENIDVV-----TTIDSIIKSLTKTTVKGGE 299
11 -21.600[H] COG3172 Predicted ATPase/kinase involved in NAD metabolism  ali follow..  11......VAILGGESSGKSTLVNKLANIFNTTSAWE-YGRDYVFSHLGGDEIALQYSDYDKIALGHAQYIDFAVKYA---NKVAFIDTDFVTTQAFCKKYEGREHPFVQALIDEY--------DLVILLENNTPWVADGLRSLGSSVDR-------KEFQNLLVEMLEEN-----NIEFVRVEEEDY-----DSRFLRCVELVREMMGEQR. 187
12 -20.300[R] COG3911 Predicted ATPase  ali follow..  10  3NDFDRVFVLTGGPGSGKTTLIAALRRA-GFATSVV-AGRGIVRDQSSIGGTALPWSDRTLFAELMLSWEMRSYQNAVEQKGPVFFDRGVPETLGYLRLSGLPVADHVSTAAKRF--------NPRVFIAPPWPDIFAQDEERKQTPDEAKCTY--HALAEIYTEL---------GYELVPLPLAPV-----ETRLRFVLADAG........ 181
13 -20.000[F] COG4088 Predicted nucleotide kinase  ali follow..  1MP---LIIVSGYPSSGKTTRSNELKKALEDRIHQNIDNTKDYRVIIINDESLNIEKETYRESKNERGLLYSAVQRELSKSTFVICDALNYIKG--------------FRYQLYCESKSMYTTHCVIHVAVPQDLCRKFNSNKEQPYPDDVLEQLMFRYEEPIDDIWSVLIHNKNVKPNQATMVKPPAEVNYLYELDKTTQDVIMLILDNSN 218
14 -19.200[F] COG0572 Uridine kinase  ali follow..  12  6.HQCVIIGIAGASASGKSLIASTLYRELREQVGDQHIG----EDGYYKDQSHLSMEERVKTNYDHPSNLLLEHLQALKAGKPVELPLYSYTERKKETVHLEPKKVIILEGILLLTDIRLRQ-NFSIFVDTPLDICLMRVNERGRSMDSVMA-QYQKTVRPMFLQFIEPSKQYAD----IIVPRG----GKNRIAIDILKAKISQFFE.... 213
15 -19.100[F] KOG3308 Uncharacterized protein of the uridine kinase family  ali follow..  12  3.RKTIIVGVSGASCSGKSTLCQLLHAIFEGSSLVHE-------DDFYKTDAEIPVSLNLDAFLENLHYIRDNRENKNVAPEALIEYADIIKEFKAPAIPTLEQHLVFVDGFMMYVNEDLIN-DIRLMLVTDFDTLKRRREARLEGFWQDPPHYFENYVWPGYVHGHSHLFVNGDDKRIQLSPSSKMSV---RDNVQWAINSILNALQ.... 230
16 -19.000[G] COG3265 Gluconate kinase  ali follow..  11  2..SGKCIIVMGVSGTGKSCVGQALALALGAKFID--------GDDLHPRANIQKMAAGQPLNDQDLERLSDVAYSLQQKNEVGFLV-------------------SALKKQYRDRLREGNEGIRFLWLTGDYDLVLHRMQQRGHFMPESLLKSQFATLEAPGSD----------EPDVIPIDISS--------SIADVVEHCIAALSLENH 171
17 -18.800[S] COG4185 Uncharacterized protein conserved in bacteria  ali follow..  12  9LEQPVFLIVAGPNGSGKSSVYANADLELEGRSVWIV-------DLLAGRISEVENKPLPEANLVAVQRIEAWIQSSISVHKTIGVETVLSTDKYR--------------RLVEAAEAVGFAIWLFYTVLDSPERSIERIKLRVAKGGHDVPADKVRARYARSLDQLPWFLERADRAWILIGEKQDGVIGLDENALAVVASAVKSIATE... 206
18 -18.300[G] KOG3354 Gluconate kinase  ali follow..  16  12.PYKYVFVVIGPAGSGKTTMAKAVSEKLGFEYIE---------DDLHPKANIEKMSQGHPLNNDRWGWLHNCGGACAMELDKESIKGVVLTCSALKRS---------YRDILRSSLEHRPAILRFIYLAASRETLIKRTTSRKNHY---MKADMVESQLAILEA-------TADEKDVITISVEN----GKEQSEEECLDIVHKMVNENKQ 192
19 -18.100[P] COG3709 Uncharacterized component of phosphonate metabolism  ali follow..  16  12LSPGTMIVIVGPSGAGKDTLMDYAAAQLGFHFTRRVITRSC--HEFNQLEDAGAFAVSWQAHGLKY--IPAAVYRHLEAGDVVIAN-------------GSRSALPHFGTAFSRL--------KVVNIVARPDVLARRLEQRGRESRDDIL-----------RRLERSSLAVAGDFDVTTVD--------NSGAIEDAGKTIMQVLQQSA. 194
20 -17.800[F] COG1102 Cytidylate kinase  ali follow..  12  3.KGCLVITVSGLAGSGTTTLCRNLAKHYGFKHVYAGLIFRQMAKERGMSLEEFQKYAEL----EIDREVDRRQVEAAKECNVVIEGRLA-----------------------------VKNADLKIWLDAPIRVRAERVAKREGISVEEAFMKIAEREMQNRKRYLNLYGIDINDLSILIIDTSKWSP---EGVFAIVKAAIDHLYEKV.. 181
21 -17.600[F] COG0283 Cytidylate kinase  ali follow..  12  1MNRQKVIAIDGPGASGKGTVAARVAAALGYDYLDT--------GALYRLTALYAQKQGVGW-EENVSELAKKLPAVFSDSRILLGGEDVSDGIRTEAIGMGASAVAQLPKVRASLLQRFPQAELKIFLTAESKI---RAERRAKQIGIPCEGLAFERILSDIEA--DEADRNRKVAPLLLLDTSRLTIEETVKKVLDWYRKV......... 218
22 -17.100[R] KOG3062 RNA polymerase II elongator associated protein  ali follow..  13  3.....LVVITGLPASGKSTRARQLRDHFVERGRKVHLISENEAVPKAGFGKNSHTGDSQKEKVVR-SDLKSEASRHLNQEDLVILDAGNYIKG--------------YRYELYCMSKVSRTTQCTVFTCIPQEEAWTFNSQRTAPDELPGDSERVQPVDNSDVPY.............................................. 147
23 -16.700[F] KOG3079 Uridylate kinase/adenylate kinase  ali follow..  12  32LMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGF--------------PRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASK--------SVDEVFDEVVQIFDKEG. 228
24 -16.500[R] COG4639 Predicted kinase  ali follow..  16  5IPELSLVVLIGASGAGKSTFARKHFQPF------EVISSDFCRGLVSNDENSQSASRDAF------DVLHYITTKRLAAGKLTVID----------ATNVQPEDRKTLLQ----MAKQYHCFTVAIVFDLPEELCHERNQQRS---DRQFGSHVVRRHTQMLRRSLR---------SLEKEGFRYVYTLKSPEEIANVAIELQPLWNNKKH 177
25 -16.200[TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin  ali follow..  16  63.DGLILVGLAGPSGAGKTIFTEKILNFMPSIAIIN-------MDNYNDGTRVIDGLTDYDTLLDNIHGLRD--------GKPVIYDFKSSSRIGYRTLEVPSSRIVILEGIYALSEKLRPLLDLRVSVTGGVHFDLVKIQRAGQEPEEIIH-QISETVYPMYKAFIEPDLKT---AQIKILNKFN.......................... 241
26 -15.300[R] KOG4622 Predicted nucleotide kinase  ali follow..  12  16.RKRGLCVLCGLPAAGKSTFARALAHRLQQEVAYDDVMPDAFLAGARARPAPSQWKLLRQELLKYLEYCYLLTKTAVSRPLFLVLD--------------DNFYYQSMRYEVYQLARKYSLGFCQLFLDCPLETCLQRNGQR----PQALPPETIHLMGRKLEK---NPEKNAWEHNSLTIPSPACASEASLEVTDLLLTALENPVKYAED 256
27 -15.200[C] COG3954 Phosphoribulokinase  ali follow..  12  3.AKHPVIAVTGSSGAGTTTTSLAFRKIFAQLNLHAAEVE---GDSFHRYTRPEMDMAIRKARDAGRHSLLEHTFIEYGQTGKGQSRKYLHTY---WQPLPEPTDVLFYEGLHGGVVTPQHD-DLLVGVVPIVNLEWIQTSERGHSREAVMDS--VVRSMDDYINYITPQFSRTH----INFQRVPTVDTSNPFAAKGIPSLDESFVV.... 231
28 -14.100[FH] KOG2702 Predicted panthothenate kinase/uridine kinase-related protein  ali follow..  11  125.NLKRLVGLAGPPGAGKSTVANEVVRRVNKLWPQKAASFDA-MDGFHLYRSQWTFDPALLLCLKKLKNEGSVYVPSF--------DHGVGDPVEDDIFVSLQHKVVIVEGNYILLEEG----DEKWFIDVNLDTAMQRVENR--HISTGKPPDVAKWRVDYNDRPNAELIIKSKTNADLLIRSMNI......................... 333
29 -13.500[F] COG0194 Guanylate kinase  ali follow..  17  43.ERGLLIVLSGPSGVGKGTVRQAIFSQEDTKFEYS-------ISVTTRSPREGEVNGVDYFFKTR-DEFEQMIADNKLLEWAEYVGNYYGTPVDYVEQTLQDGKDVFLEQGALQVRNAFPEGLFIFLAPPSLSELKNRIVTRGTETDALIE----NRMKAAKAEIEM---------------MDAYDYVVENDNVETACDKIKAIVLAEH. 227
30 -13.300[H] COG1072 Panthothenate kinase  ali follow..  11  78.RIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVE----TDGFLHPNQVFPESYDMHRLVKFVSDLKSGVPNVTA-----VYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYP-DFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMTLWKEINWLNLKQNILPTRERASLIHAVEEVRLRK.. 308
31 -13.200[S] COG2326 Uncharacterized conserved protein  ali follow..  13  57.GARIVIVFEGRDAAGKGGVIKRITERVSPRVFRVVALPAPTDRE------------------KTQIYMQRYIQQFPAAGEVVIFDRSWYNRPGVERGFCSEKKAKRFLEIAPRFEAAMIESGIVLFLDVSEEEQDRRFRQRINDPLRQESYRRWWDYTRAYDEMIRM--TDTDDAPWWIVPSDNKKQAR--NCIAHILSSIPYERVKFED 258
32 -13.100[E] COG0703 Shikimate kinase  ali follow..  14  68MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSD-RTGADVGWVFDLEGEEGFR----------DREEKVINELTEKQGIVLA----------GGSVKSRETRNRLSA------------GVVVYLETTIEKQLARTQRDKKR------LHVETPPREVLEALANERNPLYEEIADVTIRTDDQS-------AKVVANQIIHMLES... 239
33 -12.900[S] COG5324 Uncharacterized conserved protein  ali follow..  10  389.RTKFLIFPISVIGCGKTTTSQTLVNLFPGHIQNDDITGKDKSQLMKKSLELLSKKEIKCVIVDRNNHQFRERKQLF----------------------------EWLNELKEDYLVYDTNIKVIGVLSEIRDITLQRVIKRGNNHQEKKVVGIMNGFLKRYQPVNLDKSPDNMFDLMIELDFGQAD--SSLTNAKQILNEIHK....... 579
34 -12.600[L] KOG2134 Polynucleotide kinase 3` phosphatase  ali follow..  15  11KAKQIVVLLIGPPGSGKSTFCDTAMRSSHSRICQDIVNNGKAGTK---------------------AQCLKMATDSLREGKSVFIDRC----------NLDREQRSEFIKLGGP------FEVHAVVLELPAQVCISRSVKR-TGHEGNLQGGRAAAVVNKMLQSKELPKVNEGFSRIMFCYSDA.......................... 161
35 -12.400[P] KOG0635 Adenosine 5`-phosphosulfate kinase  ali follow..  10  113.QKGCVVWITGLSGSGKSTVACALSKALFERGKLTYTLDG--------DNVRHGLNRDLTFKEHRTENIRRIVAKLFADVGVICIASLISPYRRDRDACRSLLPDGDFVE---------------VFMDVPLHVCESRDPKGLYKLARAGKIKGFTGIDDPYEA---------PVNCEVVLKHTG---DDESCSPRQMAENIISYLQNKG. 289
36 -12.200[F] KOG0707 Guanylate kinase  ali follow..  13  135.NAEKPIVISGPSGVGKGTLISMLMKEFPSMFGFS-------VSHTTRSPRSMEMDGVHYHFADK-KVMEKEIKDGKFLEFASVHGNLYGTSIESVEAVTDSGKRCILDQGARSVRASSLDAIFIFVCPPSMKELEDRLRARGTETEEQIQ----KRLRNAEAEIKEGI------------SSGIFGLILYNDNLEECYKKLKVNHLLLI. 322
37 -12.100[P] COG0529 Adenylylsulfate kinase and related kinases  ali follow..  10  1.QKPAVLWFTGLSASGKSTIANRLEQRLHALGKHTYLLDG--------DNVRHGLNSDLGFSADRVENIRRVVARLMADAGLITPVSFISPFREERDQVRARLPEGEFIE---------------IFIDTPIEECMARDPKGLYAQALRGEIKAFTGIDSPYEP---------PVAPELRLNTAGRT-------VDELIAEVENYLAERG. 173
38 -12.000[F] COG1618 Predicted nucleotide kinase  ali follow..  12  8.KTMLRIAVTGSPGVGKSTVVAKTAEKLAEKP---------RTAEIRKEGHREGFSIRDLATGKTGILSHVKGSGPRLGKYHVNLD--------------------DLERIGANAVRNALACDLVVIDEIGPMELISQSFVSAVEEVLESDKPVLAVLHHSSRHPLAQ--RFRKGFEVLTVDKGNRD-----ELPEKITNRFLRKL..... 183
39 -12.000[OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase  ali follow..  11  1MKRPLIIGVGGPVGAGKTMLIERLTRYLSTKGYSMAAITN--------------------------DIYTKEDARILLNTSVLPADRIAGVETGGCPHTAIREDASMNFAAIEEMCDKHPDLQLLFLYIIDVAQGEKIPRKGGQGMIKS-KVDLAPYVGANVEVMKADTLKSRGNKDFFVTNL------KTDEGLKSVADWIEKRLQLALL 204
40 -11.900[F] COG0563 Adenylate kinase and related kinases  ali follow..  3......LILMGLPGAGKGTQAEKIIEKYGIPHI----STGDMFRAAMKNETELGLKAKSYM--DAGELVPDEVTIGIVRDR--LSQDDCQNGFLLDGFPRTVAQAEALEDILASLDKKL---DYVINIDVPEQLLMDRLTGR---QRDDDKPETVKKRLEVNQKQAQPLIDFYSEKGYLQ--------INGDQDISRVFEDINELLKGLSS 217
41 -11.800[F] KOG3078 Adenylate kinase  ali follow..  10  13.PKGIRAVLLGPPGAGKGTQAPRLAENFCVCHL----ATGDMLRAMVASGSELGKKLKATM--DAGKLVSDEMVVELIEKN--LETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKL---DSVIEFSIPDSLLIRRITGR---RRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS--------IDASQTPDVVFASILAAFSKATS 232
42 -11.500[R] COG3910 Predicted ATPase  ali follow..  35..KTPITFFAGNNGSGKSTLLEGLAAGMTAYYLQHAETVAKAFYFARKKYPKIRMFLRAEDVLGYIRRQNENALDDFRWEREKALKKGEDFPEETPEIFRGIVRNNSLDRRSHDIMHRRLHGAGLYFLDEPESPLSPQKQLELAAIIRQAADSGGQLIIATHSPVLLAIP----EATIYYFDEDGIDELENIAFLRRFLDRPSKYLDD... 258
43 -11.200[H] KOG3220 Similar to bacterial dephospho-CoA kinase  ali follow..  12  2....FIVAVTGGIATGKSTISKVFERVFGDEVLLPEINRAVLGKMIFEDKELRGKLNKITHPTIHRKIFWQVCKLLVTGHAWIVLD----LPLLFETGVLMD--------------------HKIVCVTCDSDKQLERLIARNELSESEARHRVDSQMPLDKKCEKSHF----------VID-NNGSVEEAESSAMSIYNLMRDSKQHWLN 205
44 -10.900[J] KOG1384 tRNA delta(2)-isopentenylpyrophosphate transferase  ali follow..  10  63.RKDKVVVILGATGAGKSRLSVDLATRFPSEIINQVYEGLEITTNQITLQDRRGVPHHLLLTAGEFRSAASNVVKEITSRQKIAGGSNSFVHALLAQRFDPKFDPFSSGS--CLISSDLRYECCFIWVDVSETVLYEYLLRR----DEMMDSGMFEELSRFYDPVKSGLETRFGIRKAIGVKKMIKWDALRKAAYDKAVDDIKRNTWTLAK 296
45 -10.900[H] COG0237 Dephospho-CoA kinase  ali follow..  13  3....LVIGLTGGIASGKSTVANMLIEEFGEDILLSDIDRKKLGALVFTNEQKRLALNAIVHPAVRQEMLNRRDEAVANREAFVVLDIPLLFESKLESLV-----------------------DKIIVVSVTKELQLERLMKRNQLTEEEAVSRIRSQMPLEEKTARADQ------------------VIDNSGTLEETKRQLDEIMNSWA. 197
46 -10.500[QP] COG4615 ABC-type siderophore export system, fused ATPase and permease components  ali follow..  10  346IKRGELLFLIGGNGSGKSTLAMLLTG-------------------LYQPQSGEILLDGKPVSGEQPEDYRKLFS-------AVFTDVWLFDQLLGPEGKPA-----------------------------NPQLVEKWLAQLKMAHKLELSNGRIVKLSKGQKKRVALLLALAEERDIILLD--EWAADQDPHFRREFYQVLLPLMQEMGK 501
47 -10.300[E] COG4917 Ethanolamine utilization protein  ali follow..  14  1MKR---IAFVGSVGAGKTTLFNALQG----------------------------------------NYTLARKTQAVEFNDKGDID--------------TPGEYFNHPRWYHALITTLQDVDMLIYVNDPESRLPAGLLDIGVSKRQIAVISKTDMPDADVAATRKLLLETGFEEPMFELNS------HDPQSVQQLVDYLASLTKQEE. 150
48 -10.200[R] COG4240 Predicted kinase  ali follow..  86.KRPFIQGILGSQGTGKTTMSLVIQLILQHLGYRTLSLS---LDDLY-------------KTYSDRLVLLQQDPRLIWRGPPGTHDIDLGLNVLEQ---IRQGKSPVIVPRFDKSAHAITGVDILIF----RPIDPSLFNFPPSPILTDEDKAFARDMNLRLNHYLPLWEK----DSLILLYPTDYRCSLEWRKQAEQKTQIEEFVNYFWR 297
49 -9.880[S] COG4916 Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain  ali follow..  11  35SQVGKHLLIEGPSGIGKTCVVFKVFEELQWSVGCRDQNAEQIIDDFLKNAAAGNALSPCVLVIDDFHLLSQAKRMEIGSTLKRLSDKVILIGIPTAGVSLLSDAYDLGPRLGSYALTRASDVEIDKLISEGEQALAVLFEDRDVLLAESAGNFWLAQYVCNKVCAIEEVYETQDDAKILTFDILGIRGRLMAELTQRYLPIARTFAKGKRW 261
50 -9.840[E] COG4161 ABC-type arginine transport system, ATPase component  ali follow..  25CPQGETLVLLGPSGAGKSSLLRVLSGTLNIAGNHFDFTKTPSDKAIRDLRRNVGMVFQQYNLWPHLTVQQNLIEAPCRVLGLSKDQALARAEKLLERLRLKPYSDRYPLHL--AIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETNITQVIVTHEV-----VARKTASRVVYMENGHIVEQGDASCFTE.............. 230
51 -9.770[S] COG4983 Uncharacterized conserved protein  ali follow..  10  498..QSAYLFITEETGIGRNWLSSVLVRVLRGYVAAGIDIQEMLDGTFNGRLSRKLLAVVDEAKAGMQGYGRWSHSEKL---KSMINPEMRRINEKHGLEF-HRQSPDYYERIYSQIANPDFISAVRKRL---ELLDISGFKPGAIPDMNEAKRKALGAMASDLDNLLAAFRDEWPGPLAERSDVINYLHVSIAKLPGE--KTINKLIEQAG. 730
52 -9.710[U] KOG0090 Signal recognition particle receptor, beta subunit (small G protein superfamily)  ali follow..  13  53.TKSNTVLLSGLSGSGKTVLFYQL----------------------------------------RDGSSHQGAVTSMEPNEGTFVLHNENNTKKGKVKPVHLIDVPGHSRLISKLEEYLPRAAAVVFV----------VDALEFLPNIRAASEYLYDI-------LTNASVIKNKTPVLLC-CNKTDKVTAHTK-EFIRKQMEKEIDKLRV 203
53 -9.640[O] COG4133 ABC-type transport system involved in cytochrome c biogenesis, ATPase component  ali follow..  24LNAGEWVQITGSNGAGKTTLLRLLTGLSRPDAGEVLWQGQPLHQVRDSYHQNLLWIGHQPGIKTRLTALENLHFYHRDGDTAQCLEALAQAGLAGFEDIPVNQLSAGQQRRVALARLWLTRATLWIL-----DEPFTAIDVNGVDRLTQRMAQHTEQGGIVILTTHQPLNVAESKIRRISLTQTRA......................... 204
54 -9.420[L] KOG2859 DNA repair protein, member of the recA/RAD51 family  ali follow..  10  40LRAGNVVEITGASTSAKTQILIQAAISC-------------ILPKTWNGIHYGGLGKLVLFLVLRLSQMLKHRLLQANWLGNGAWWQLEESNVKSCKSAEEKTKTVFDEELYASCMKR-----FLYVRCYDSLELLSSLKT--------------------LHYRIQQQEACGSQVGVLMIDSIGAFHNRKSLSLTNVVETIVQELKKLLL 233
55 -9.380[E] COG1126 ABC-type polar amino acid transport system, ATPase component  ali follow..  13  24ITQGEVVVIIGPSGSGKSTLLRCINVITRGQLIVDGLDVNSPNIDERQIRLEAGMVFQQFYLFPHLTALENVAFGPTKVRGTSKEEAKKQALALLSKVGLEDRAHHYPAEL--AIARALAVKPKLMLFDEPTSALDPELRHEVLTVMKDLAEEGMTMVIVTHEV-----FAQKVASRLIFIDKGRIAEDGDPDSL................ 223
56 -9.370[R] COG0802 Predicted ATPase or kinase  ali follow..  16  25LLAGDVITLEGDLGAGKTSFTKGLALGLGI--------KRVVKSPTFTIIREYKGRLPLYHMVYRLNEEEEDL-----------FDEYFHGDGV------------TVVEWASLIEGRLPPVRLAITITHAGENERQSFTAYGERWEEVLK............................................................ 147
57 -9.330[E] COG4598 ABC-type histidine transport system, ATPase component  ali follow..  12  28ANAGDVISIIGSSGSGKSTFLRCINQTINLVRDKDGQLKVADKNQLRLLRTRLTMVFQHFNLWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEM-----FARHVSTHVIFLHQGKIEEEGAPEQLNPQSPRLQRFLKGSLK 257
58 -9.260[R] COG4136 ABC-type uncharacterized transport system, ATPase component  ali follow..  24VDKGDIVTLMGPSGCGKSTLFSWMIGALAEQF--ELWLNEQRIDILPTAQRQIGILFQDALLFDQFSVGQNLLATLKGNARRNAVNDALERSGLEGAFHQDPATLSGGQRARVALLRALLAQPKALLLDEPFSRLDVALRDNFRQWVFSEVRA.......................................................... 182
59 -9.220[R] KOG2878 Predicted kinase  ali follow..  13  23.GRPFILGISGPQGSGKSTLASALDTELTRKNESVVKFS---LDDFYLTHAE-AGTHDVTFLNNVLNAFVKGSDEEVSTTTYVIFERSTRWQNIEGSLLWVNRKLADYQPIFQKIDSELEAQEINYVYRWRLQQEHALKARIHKGMSDEEVIEFVNHYMPQYVFYLGTLSNKVHLNPEIILDENR.......................... 271
60 -9.220[H] COG3840 ABC-type thiamine transport system, ATPase component  ali follow..  22VERGEQVAILGPSGAGKSTLLNLIA--FLTPASGALTIDGVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIPGLKLNAVQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSTSCQQQMTLLMVSHSV----EDAARIATRSVVVADGRIAWQGMTNELLSGKASASALLGITG. 232

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.