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Query: gi|30260213|ref|NP_842590.1| DNA polymerase III subunits gamma and tau (BA_0019) [Bacillus anthracis str. Ames], from B.anthracis

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDERVTTEDVLAVTGSVSQQYLGNLVECIRENDVSRALRIIDEMMGKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVMVDEQFRMLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGADRLQAIMNRMQQLEKELEQVKKNGVPVGVQQEVKETRAAPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKAYNKVAFAVLLENSEPVAASDDTYVLAFQYEIHCKMASENREAMDTVEQALFELLSKKLNMIAIPKSEWGKIREDFLKREGGSSEESPEKKEDPLIEEAIKLVGQELIEIKELast
1 -133.000[L] COG2812 DNA polymerase III, gamma/tau subunits  ali follow..  51  1MSYQALYRVWRPQKLQDVVGQEHITKTLQNALVQEKFSHAYLFSGPRGTGKTSAAKIIAKAINCEQAPIAEPCNECRACKGITSGSIVDVMEIDAASNNGVDEIRDIRDHVKFAPSEVRYKVYIIDEVHMLTTGAFNALLKTLEEPPSHAIFILATTEPHKIPLTIISRCQRFDFKRISNDALVGRMKEILTHEGIEAEDEALVLVARAAEGGMRDSLSLLDQAISFADERVTVEDVLAITGAVSHEVLTQVVESAQKGETAEALQLVNQLLANGKDPLRFVEDLIYYYRDLMLFKAAPEASQLLERAQINDSFKTLAGEINDASLFAAIEILNDCQQRMRWSSHPRVALELGVVTLCQQVVQVPASPQAGAATHPNQQLEQAVQSLKVNGVANVTAEEPKTKQASRRPLKQMPKSQAPTGKIKELLKEASKQQLQLVNGRWGEVMERVKAQN-VPAHAWLMDCKPAAASPKFILLAFQNEMHRDMI--DTKFRPFIESVLRDIFQAPLDFQTLLQSQWNKVKEE---YVRDQRGDGEEPSSDPLIEEAIKLVGSDLIEVKD 564
2 -72.100[L] COG0470 ATPase involved in DNA replication  ali follow..  20  10KENLPWVEKYRPETLDEVYGQNEVITTVRKFVDEGKLPH-LLFYGPPGTGKTSTIVALAREIYG-------------------KNYSNMVLELNASDDRGIDVVRNQIKDFASTIFSKGFKLIILDEADAMTNAAQNALRRVIERYTKNTRFCVLANYAHKLTPALLSRCTRFRFQPLPQEAIERRIANVLVHEKLKLSPNAEKALIELSNGDMRRVLNVLQSCKATLDDEISDDVIYECCGAPRPSDLKAVLKSILEDDWGTAHYTLNKVRAKGLALIDLIEGIVKILEDYELQNEETRVHLLTLADIEYSISKGGNDQIQGSAVIGAIKASFENETVKA............................................................................................................................................................................................................................. 338
3 -70.400[L] KOG0991 Replication factor C, subunit RFC2  ali follow..  22  33HYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARALLG-------------------PALKDAMLELNASNDRGIDVVRNKIKQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFG-FINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLK---------------------------LEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS................................................................................................................................................................................................... 354
4 -68.000[L] KOG0990 Replication factor C, subunit RFC5  ali follow..  20  36SKATPWVEKYRPQSLDDVAAHRDIIDTIDRLTNENKLPHLLLY-GPPGTGKTSTILAVARKLYG-------------------PKYRNMILELNASDDRGIDVVRQFASTQSFSLGKSSVKLVLLDEADAMTKDAQFALRRVIEKYTKSTRFALIGNHVNKIIPALQSRCTRFRFAPLDGVHMSQRLKHVIEAERLVVSDCGLAALVRLSNGDMRKALNILQSTHMASKKQITEEDVYLCTGNPLPKDIEQISHWLLNKPFDECYKDVSEIKRKGLAIVDIVKEITLFIFKIKMPSAVRVQLINDLADIEYRLSFGCNDKL---QLGAIISTFTHARSIIVGAAK......................................................................................................................................................................................................................... 369
5 -57.100[DL] KOG2035 Replication factor C, subunit RFC3  ali follow..  15  1MAL--WVDKYRPKDLLGKDGVDYHIEQAHLKFLSADCMPHLLFCGPSGAGKKTRIKCLLRELYGVGKSFTSPSNKKLEIQTVSSNYHIEMTPSDVGIYDRVDLVKEMAQTSQIESTQRSFKVVVLCEADSLTRDAQHGLRRTMEKYANNCKIVLSCESLSRIIEPLQSRCIIINVPAPTDEDVTKVLRKVIERESFLLPENVLQKIVEKSEGNLRRAILMTEALRMENESGVAESVVIPVPEWEIQETARLILQKQSSDMLLKVRERLYELLSRCIPPTVIFKKLLEHLLPKCPPQIARE----------------------------VVSEAAKFEHRLVLGQKAIFHLEGFVAAFMDI.......................................................................................................................................................................................................... 345
6 -57.100[L] KOG2028 ATPase related to the helicase subunit of the Holliday junction resolvase  ali follow..  18  98RQHQPLSERMRPRTLDDVVGQDHLLSLLRSAVESNRLPSIVFW-GPPGTGKTSIAKSLINSSKDPSLYRFVSLS---------------------AVTSGVKDVRDAVESAKRLNLEGRKRVLFMDEVHRFNKSQQDTFLPVIEDGSILFIGATTENPSFHLITPLLSRCRVLTLNPLKPNHVETLLRRAVDDSSVEVDDSVIEFLANNCDGDARVALNALEISATMATTRAGTDAVVSIDGEQHYNLISALHKSMRGGDANAAIYWLARMLEGGEEPLYIARRLIRFASEDIGLADPSALTQAVACYQASHFLGMPECNVILAQCTAYLALAPKSIAVYRAIGAAQKVVKDSVGQNEGVP......................................................................................................................................................................................................... 462
7 -56.400[L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase  ali follow..  18  12EDFRPLAARMRPQTVEQYIGQQHILKPLRRALEAGHI-HSMILWGPPGTGKTTLAEVAANYANAE-------------------------VERVSAVTSGVKEIRAAIEKARENKLSGRRTILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARVYKLTSLNQQEILQALHQAIADTAAVFADNVLDRLAELVNGDARMSLNYLELLYDMAREDIDLPLLAEVAGDIWYDLISAVHKSIRGSDPDAALYWAARMISAGCDPLYIARRLLAIASEDVGNADPRGMQVALAAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSDAHNLPEFEV............................................................................................................................................................................................................ 369
8 -47.300[L] COG2255 Holliday junction resolvasome, helicase subunit  ali follow..  17  14NDEESIDRAIRPKLLTEYVGQPHVREQMEIFIQRGDALDHVLIFGPPGLGKTTLANIIANEMGVNLRTTSGPVLEKAGDLA------AMLTNLEPHDVLFIDEIHRLSPVVE----EILYPAMEDYQLDIMIGEGPAARSIKLDLP--PFTLIGATTRAGSLTSPLRDRFGIQRLEFYQVADLEHIVSRSAKCLGLELTPEGAHQLARRSRGTPRITNRLLRRVRDFAEVR--ADGAINGEVAMKALDMLNVDAEGFDFMDRKLLLAVIDKFMGGPVGLDNLAAAIGEERETIEDVLEP....................................................................................................................................................................................................................................................................... 303
9 -43.600[K] KOG2680 DNA helicase TIP49, TBP-interacting protein  ali follow..  18  148SSGVASKSGKMTMKTTDMETVYDMGAKMIEALNKEKVQSGDVIAIDKATGKITLGRSFSRSRDYDAMGAQTQCPEGELQKRKEVVHCVTLHEIDVINSRTQGFLAEVREQIEEGKAEIVPGVLFIDEVHMLDIECFSFLNRALENEMSPILVVATNKSPHGIPIDLLDRLLIITTQPYTDDDIRKILEIRCQEEDVEMNEEAKQLLTLIGDTSLRYAIHLITAAALSCGKVVEVEDIQRVYRLFLDVR--RSMQYLVEYQSQYMFSEPIKNDEAAAEDEQDAMQI..................................................................................................................................................................................................................................................................................... 469
10 -35.000[L] KOG1942 DNA helicase, TBP-interacting protein  ali follow..  15  182ALIKEKVAVGDVIYIEANSGAVKRVGRSDAFATEFDLEAEEYVPLPKGEVHKKKEIVQDVTLQDLDAANARPQGGQDILSLMGQMMKPRKTEITDKLRQEINKV--VNRYIDEGVAELVPGVLFIDEVHMLDMECFSYLNRALESSLSPIVIFATNRGPHGVPIDLLDRLVIIRTQIYDPSEMIQIIAIRAQVEELTVDEECLVLLGEIGRTSLRHAVQLLSPASIVARDNICKADIEEVTSLLDAKSSAKLLHEQQEK............................................................................................................................................................................................................................................................................................................... 455
11 -22.400[L] KOG1968 Replication factor C, subunit RFC1 (large subunit)  ali follow..  21  364........KYAPTSLKDICGNKGVVQKLQKWLQD---YKAVLLSGPPGIGKTTAAHLVAKLEG------------------------YDVLELNASDTRSKRLLDEQLFGVTDSQSAKSRLVLIMDEIDGMSSGDRGGVIKKSMIP----IICICNDRAHPKLRPLDRTTFDLRFRRPDANSMRSRIMSIAYREGLKLSPQAVDQLVQGTQSDMRQIINLL-STYKLSCSEMTPQNSQAVIKNSEKHIVMKPWDICSR................................................................................................................................................................................................................................................................................................................ 620
12 -21.000[DL] KOG1970 Checkpoint RAD17-RFC complex, RAD17/RAD24 component  ali follow..  14  94........KYKPETQHELAVHKKKIEEVETWLKAKQGGSILLITGPPGCGKTTTLKILSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRAT-DDLRTDKKIILVEDLPNQFYRD-EVLRKYVRIGRCPLIFIISDSLSGDFPKEIQEEISNISFNPVAPTIMMKFLNRIVTIEANKNDKTSLELLCQGCSGDIRSAINSL-QFSSSKGENNLRPRKKGM.................................................................................................................................................................................................................................................................................................................................. 358
13 -19.500[L] COG1466 DNA polymerase III, delta subunit  ali follow..  11  4................PMQKSLTSFDDFSQAY--AEKVPAIALIGSA-------LEDDKDALI-------------------ELLVSESFKELGGQG-----MPATLMSWTETFALFQEHETLGIIHAEKFPLATKEFLSRYARNPQPHLTILIFTTKQEC--RELSKALPSGEWPADRQKRIIRLLLQRAERVGISCSQSLASLFLRALASSLPDILSEFDKLLCSVGKKLDHSDIKELVVKKEKASLWKFRDSLLKRDPVEGHQQLHFLLEDGEDPLGIITFLRTQCLYGLRSI----------EEGSKENKHRMFVLYGKERLHQALNSLFYAETLIKNNVDPIVAVETLVIRMVNL.......................................................................................................................................................................................................... 315
14 -16.400[R] COG2607 Predicted ATPase (AAA+ superfamily)  ali follow..  16  49......LPDPHTFPLVRLAGVGRQTELLVRNTEVGRPANNVLMSGARGTGKSSLVKALLHEYA---------------------DKGLRLIEVDK------SDLIGLPYLLTLLKECPEKFIVFCDDLSFESGDETYKALKTLSQRCANVLVYATSNRRHLMPEYFISLSDRFGFYPFDQNDYLAAVQNWLEDFGVPYDETALQWAQTRGSRSGRSAWQFACDWAG................................................................................................................................................................................................................................................................................................................................................ 279
15 -14.500[LD] KOG2227 Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase  ali follow..  13  115...EALHVSKAP---STILCREDIFEFVKGCIDQQKAGSLYI-CGCPGTGKSLSMEKVVQQVGDWSTQAGLP-----NCTSLSKTTDIGEIKPGKNANTNSSPLQHLQNLFKQESSSSRMMLIIADEMDYLITKDRGVLYDLFMLTPFSRCILIGVANAIDLADRFLPK-MVITFRAYSKDQILRILQRLRVLSYVAFQPKALELCARKVSGDMRKALCVCRSALEILEIEVRMDHMAAALSKTFKSPVVETIQSLPQHQ-QIIICAAAKAFRGSKK-DATVGELNKLYLEICMCTVLNDQGILKVGQARRDKLKRVSLRVDESDITFALQ....................................................................................................................................................................................................................................... 495
16 -14.400[H] COG1239 Mg-chelatase subunit ChlI  ali follow..  17  55..............FPGVVGYDDTVIPLVNALLAR---QNFILLGLRGQAKSRILRAITELLGVDMPDDPNPIGAEGQHLLEAHGMELDVTVADLIGDVDPIKATSLGDTRSMHFPRANRGIFAVNELADLSPKVQVALFNILQEGDVQIVMLVFSANPEKIVTPLKDR---IGSERTHYPTDVQLGMDITAQEGVVVPPFIAELIEDIAF-SQRLPISLMELACANAERRSLVSGDAPVVRVTDVYAGLPAITGKMELEYEGELKGADNVAKD................................................................................................................................................................................................................................................................................................ 378
17 -14.300[L] KOG1514 Origin recognition complex, subunit 1, and related proteins  ali follow..  15  383.AKATLLLATRP---KSLPCRSKITAFIKGSISDDQCLGRCMYHGVPGTGKTISVLSVMKNLKAEVEAGSVS--------------PYCFVEINGLKLASPENISVIYEGLKIGKENEKPCILLIDELDVLVTRNQSVLYNILDWPPNSKLVVLGIANTMDLPEKLLPRISRLCFGPYNHRQLQEIISTRLEGINA-FEKTAIEFASRAISGDARRALEICRRAAEVADYRVIMADVEVAIQEMFQAPHIQVMKSVSKLSRIFLTAMVHELYKTGMA-ETSFDRVATTVSSICIGCDLGECRIVLCEPGEKHRLQKLQLNFPSDDVAFALK....................................................................................................................................................................................................................................... 759
18 -14.200[R] COG1223 Predicted ATPase (AAA+ superfamily)  ali follow..  22  103.............TLDDVVGQEEAKRKAKVILEGKWAPKNVLFYGPPGTGKTMMAKALS-------NEAKTP--------SVKSTKLIGEHVGDGARR-----VHELYERAR-APC-----IVFLDEFDAIASEIVNALLTELDNSNEGICTIAATNRVELLDASIRSR---FEEEEFRLPSYEERLEILRNLEEFPVPVKALELVAAASEGSGRDLVEKVIKASLHKAIAEGKDKIETKMPSRQPPKQMFV...................................................................................................................................................................................................................................................................................................................... 352
19 -13.600[R] KOG2170 ATPase of the AAA+ superfamily  ali follow..  15  75...............NLLFGQHLVKDVVVNSIKSHWYNEVLSFHGYTGSGKNYVAEIIANNTFRLGLRST-------------------VATNDFPDKNKLEEYQELRNRILTTVQKCQRSIFIFDEADKLPEQLLGAIKPFLDY--RRSIFILSNKGGGEIARITKEQYESGYPRELRLEAFERELMNFSYNEKGGLQMSELI------------SNHLIDHFVPF---PLQREHVRSCV----GAYLRKRGRGDLVSNVDFVERVLNSLQYFPESSKAFSSSGCKRVDAKTDLEMAKIRPLLSSVHFDDE.......................................................................................................................................................................................................................................................... 355
20 -13.500[O] KOG0737 AAA+-type ATPase  ali follow..  17  412.............TFADIGSLDETKESLQELVM--KPCRGILLFGPPGTGKTMMAKAIANEAGAS------------------------FINVSMSTGEDEKNVRALFTLAKVSPT-----IIFVDEVHEAMRKIKNEFMTHWDNAGDRILVLAATNRPFDLDEAIIRRFERRIMVGLPSVESREKILRTL--SKEKTENLDFQELAQMTDGSGSDLKNFCTTAA................................................................................................................................................................................................................................................................................................................................................. 629
21 -13.300[LO] COG1474 Cdc6-related protein, AAA superfamily ATPase  ali follow..  15  31...EVLRPSYTPDLLLHRNEQNSLATILVSALRGETPSNVLIY-GKTGTGKTAVTRYVGKEINCEVIDTQY-----RLLANLARHFEEEVPMTGWPTDQVFMKFKEAIDA------RDQVIIIILDEIDKLGDDVLYNLSRINTDLRKAKVSMIGVSNDLKFTEFLDPRVKELIFPPYDAEQISDILKQRAKMNDGVLGEMVIPLCAAFAHGDARRALDLLRVSGEIAEREVLEEHVRRAQEKIEIDRVVEVVRTLPTQSKLVLYSIILLRSRGREGKNVTTGEMYNVYRQLC--------HHIDVDILTQRRVTDLMSELDMLGIVNA......................................................................................................................................................................................................................................... 371
22 -13.200[O] COG0542 ATPases with chaperone activity, ATP-binding subunit  ali follow..  19  567...............KRVIGQHEAIEAVSNAIRRSRAG-SFLFLGPTGVGKTELCKTLANFL-----------DDENAMVRIDMSEFMEVSRLVGAP--GYEEGGYLTEAVRRRP----YSVILLDEVEKAHHDVFNILLQVLDD---------RLTD---------GQGRTVDFRNTVVIMTSNLGSHLIQENSTLDYPSMKELVMSVVGQHFREFINRIDETVVF--HPLGKENIREIATI----QLARLIKRMESHGYQLHFACLDFIGEVGYDPVYGARPLKRAIQQEIENPLA........................................................................................................................................................................................................................................................................ 828
23 -13.100[S] COG4916 Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain  ali follow..  14  2VDKKTLGDVFKTVGLPPYVKPKHFGEVRADISQVGK--HLLIE-GPSGIGKTCVVFKVFEELQWSQGRD--------------------FTYVGCRDQNAEQIIDDFLKNAAAGNALSP-CVLVIDDFHLLSQAKRMEILKRLQAEPAKVILIGIPTAGVSL-YDLGPRLGSYALTRASDVEIDKLISE--GEQALAVLFEDRDVLLAESAGNFWLAQYVCNKVCAIEEVYETQDDAKIL--TFDILGIRGRLMAELTQRYLPIARTFAKGKRWRPGGNKPYLEILLAL................................................................................................................................................................................................................................................................................. 276
24 -12.400[O] KOG0743 AAA+-type ATPase  ali follow..  14  699........GWGPSTFETLA-KKKIIDDMERFLKRREFKRGYLLYGPPGTGKSSLIAAMANYLK------------------------FDVFDLELSSIYENAQLKSILLSTT------NRSILVIEDIDC-GRVTLSGLLNFVD---DERIIVFTTNHKERLDPALL-RPGRMDMH---------------------CTGLGFRTLVSNYLGLGGLNHPLCEEIEAIDSTEVTPAELAEEL--------------MQEDDTDVVLRGVVSFVEN................................................................................................................................................................................................................................................................................................ 946
25 -12.300[O] KOG0726 26S proteasome regulatory complex, ATPase RPT2  ali follow..  18  182.............TYADIGGLDTQIQEIKESVE--KPPKGVILYGPPGTGKTLLAKAVANQTSAT--------------LRVVGSELIQKYLGDGPKL-----VRELFRVAE-APS-----IVFIDEIDAVGTKRYDSLLNQLDDSRGDVKVIMATNRIETLDPALI-RPGRIDRKEFPLPDEKTKRRIFIHTSRMTLAEDVLSELIMAKDDLSADIKAICTEALRERRMKVTNEDFKKSKESVLYRKKEGTPEGL.................................................................................................................................................................................................................................................................................................................. 437
26 -12.200[O] COG1222 ATP-dependent 26S proteasome regulatory subunit  ali follow..  20  146.............TYEDIGGLERQIEELNEAIV--KPPKGVLMYGPPGTGKTLMARACASKTNA-------------TFLKLAGPQLVQMYIGDGARL-----VRDAFALAK-KPT-----IIFIDEIDAIGAKRSDSLLNQLDSSSEEVKIIAATNRVDILDPALL-RSGRLDRKEFPLPNTLGRKRILIHARKMSVRDDVFDELARSTEGFNAQCKAVCVEALRKEKTEISQNDFMDGIQEVLSRKKSKLL..................................................................................................................................................................................................................................................................................................................... 398
27 -12.100[O] COG0465 ATP-dependent Zn proteases  ali follow..  18  150.............SFADVAGCDEAKEEVSELVDGGKIPKGVLMVGPPGTGKTLLAKAIA-------GEAKVP--------TISGSDFVEMFVGVGASR-----VRDMFEQAK-APC-----IIFIDEIDAVGRQTLNQMLVEMDEGNEGIIVIAATNRPDVLDPALL-RPGRFDRQVVGLPDVRGREQILVHMRRVPLDTDIASVIARGTPGSGADLANLVNEAALFAARVVSMVEFEKMMGAERRSMVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKV--TIIPRGRALGVTFFLPEGDAISASRQKSQISTLYGGRLAEEIIYGPEKVSTGASNDIKVATS......................................................................................................................................................................................................................... 498
28 -12.100[O] KOG0727 26S proteasome regulatory complex, ATPase RPT3  ali follow..  17  153.............SYNDIGGCDIQKQEIREAVE--DPPRGVLLYGPPGTGKTMLAKAVANHTTA------------------------AFIRVVGSEGEGPRMVRDVFRLAK-APA-----IIFIDEVDAIATARFDALLNQMDDQTVNVKVIMATNRADTLDPALL-RPGRLDRKEFPLPDRRQKRLVFVCTSKMNLSDEVLEDYVSRPDKISAEIAAICQEAVRKNRYVILPKDFEKGYRANVKKPDTDF...................................................................................................................................................................................................................................................................................................................... 404
29 -12.100[O] COG0466 ATP-dependent Lon protease, bacterial type  ali follow..  20  324...............SNHNGLEKVKERIIQHLAVMKLGSILLLTGPPGTGKTSLGKSIADALG-------------REYVRISLGGVRDEAEIRGHRRTYIGAIQGMRKAGTKNP------VFILDEVDKLSTS--SALLEVLDPEQSEVFFIATANSLASIPWPLLDRMETIEISAIAKDHLLPCILE-LDADKLKIEDEALKGIIDTREAGVRGLKKQLARTARFVSEKVRADMLKEVLGEARKENVPGVVTGLAWTPVGGDILFIEGTFMPGNGKLTLTGQLGDVMKESAQISLS........................................................................................................................................................................................................................................................................ 646
30 -12.000[O] KOG0740 AAA+-type ATPase  ali follow..  17  399.............NWEDIAGVEFAKATIKEIVV-RGPPKGILLFGPPGTGKTLIGKCIASQSGAT------------------------FFSISASSGEGEKMVRALFAVARQQPA-----VIFIDEIDSLSRRIKTEFLVQLDSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEAS-KQIVINLMSKEQCCLSEEEIEQIVQQSDASGADMTQLCRGASLGPIRSLQTADIATI---------PDQVRPIAYIDFENAFRTVRPSVSP................................................................................................................................................................................................................................................................................................ 657
31 -12.000[O] KOG0728 26S proteasome regulatory complex, ATPase RPT6  ali follow..  18  146.............TYEMVGGLDKQIKEIKEVIE--AQPKGVLLYGPPGTGKTLLARAVAHHTEC------------------------TFIRVSGSEGEGSRMVRELFVMAR-APS-----IIFMDEIDSIGSSRIESLLNQLDEATKNIKVIMATNRIDILDPALL-RPGRIDRKEFPPPNEEARLDILIHSRKMNLTRGILRKIAELMPGASAEVKGVCTEALRERRVHVTQEDFEMAVAKVMQKDSEKNM..................................................................................................................................................................................................................................................................................................................... 398
32 -12.000[QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism  ali follow..  16  326...........PPALRRLGGDAVIAALQAKAAKLARTRLPILIQGETGTGK----EHLARAIH-EGSGLEGP-----NCAAIPE----QLIESEGASAKGRKGLIEQADG-----------TLFLDEIGDMPLALQSRLLRVLAE-KVRIRIVSASH--RPLQTLVSQGAFREDLDRPDFDWVLEQLLKRHGDGELILSPAALSALKAHDPGNIRELDNVIGVAAALAENGVELGDLPDQLLANADTVGGNEASATLSLTLTACNWNISEAARRGLDRSTVHRQIKRY.................................................................................................................................................................................................................................................................................. 620
33 -11.700[O] COG0464 ATPases of the AAA+ class  ali follow..  18  487.............SWEDVGGLERVKELLKEVVE--EAPKGVLLYGPPGTGKTLLAKAIAHESD------------------------ANFITAKGSDGESEKRIAEVFTRARVAPS-----IIFLDELDSLAPIILNQLLSEMDEELRAVVVIGATNRPDIIDPALL-RPGRFDELLVPVPDEGARFRVHTKNMALAEDVD-IEKLVSFTDQYTADIAAVCKKAGDLHAKKVRQKHFLQAIEETGPSVTPDTMKYYIKGELRKRKS........................................................................................................................................................................................................................................................................................................ 755
34 -11.600[U] COG3267 Type II secretory pathway, component ExeA (predicted ATPase)  ali follow..  16  19...........ARYLYLSQRHQEAIVHLQAGLGDGG----AMLTGEVGTGKTTVARAILASLP-GKTRAGMILNPTFSDLELLE-AICDEFEVSYPKKATLKKTQVLHEFLLAEHAQGIQVLLMIDEAQHLAPDVLEQLLTNLETESHKLLKVLLIGQPEQLAQRITGRYHLLPLNEEQTADYIRFRIEQASGNPELFNRKACQWIAEQTHGIPRLINLVCDAALKQAEPTLSLARIKLAC................................................................................................................................................................................................................................................................................................................................. 262
35 -11.600[O] KOG0739 AAA+-type ATPase  ali follow..  17  125.............RWNDVAGLEGAKEALKEAV--RTPWRGILLFGPPGTGKSYLAKAVA-----------------------TEANNSTFFSVSSSDGESEKLVKNLFELARHKPS-----IIFIDEVDSLNESEAARRIKTVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEA-AQMFRLHLGSTPHNLTDANIHELARKTEGSGADISIIVRDSL................................................................................................................................................................................................................................................................................................................................................. 342
36 -11.500[O] COG1219 ATP-dependent protease Clp, ATPase subunit  ali follow..  17  77...............QYVIGQERAKKVLAVAVYNHYKRSNILMIGPTGSGKTLLAETLARLLN------------------------VPFTIADATTGEDVENIQKLLQKCDYDVEKAQMGIVYIDEIDKISRGVQQALLKLIEG--RNILFICGGA--AGLERVIQNRSAR---GGIGFNAEVRSQEMGKKVGEAFKEVEPEDLVK----GLIPEFVGRLPVIATL--DELDEAALMQILTEPKNALTKQYAKLFEMEGVDLEFDALKAVARKALERKTGARGLRSILEGILL............................................................................................................................................................................................................................................................................ 381
37 -11.500[O] KOG0741 AAA+-type ATPase  ali follow..  14  216.............EKMGIGGLDKEFSDIFRRAFAFRVFPGILLYGPPGCGKTLLARQIGKMLNAR--------------PKVVNGPEI-LNKYVGESEANIRKLADAEEEQRRLGANSGLHIIIFDEIDAIHDTVVNQLLSKIDEQLNNILVIGMTNRPDLIDEALL-RPGRLEVKEIGLPDEKGRLQILMRGHQLLSADVDIKELAVETKNSGAELEGLVRAAQSTAMNRHIKASTKVEV-QVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIKWGDPVTRVLDDGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSC.............................................................................................................................................................................................................................. 599
38 -11.500[K] COG2909 ATP-dependent transcriptional regulator  ali follow..  13  1...MLIPSKLSPVRLQNTVVRDRLLVKLSSAANYRLT----LINCPAGYGKTTLIAQWAA-----------------------DQSNLGWYSLDESDNQ-FIELSNWDGPL----------YLVIDDYHLITNDAIHEAMRFLRHQPENLTLIILSRTLPSLG---IANLRRDQLLELGMQQLHEAQQFFECRLSSPLEQGDSSRLCDEVEGALQ-ALSSAKRLAGLNASHLSDYLVDEVLDQVDSKARAFLLRCSVLRSMNDAL----VRLTGEDNGQQLLEELER--QGLFIHRMDDSAEWFCFHPLFATFLRQRCQWELALELPELHHAAAE................................................................................................................................................................................................................................... 349
39 -11.500[KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains  ali follow..  16  268.............HIEQLVGECRVMRQLKRLISRAPSPSSVMVVGESGTGK----EVVARAIHKLSGRRNKP-----NCAAIPE----QLLESEGASANGKTGLIQAANT-----------TLFLDEIGDMPLMLQAKLLRAIEA-QVDIRIISATNQ-NVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEILRKHRPGNLRELSNLMEYLVNVVGEVIDSTLLPPNL-LSLDDAGGTALEEMEKQMIREALSRHNSKKQVADELGIGIATLYRKIKKYELLNT......................................................................................................................................................................................................................................................................... 592
40 -11.500[O] KOG0651 26S proteasome regulatory complex, ATPase RPT4  ali follow..  20  148.............SYSDVGGLAEQIRELREVVE--TPPKGCLLFGPPGTGKTLLARAVASQLDC------------------------NFLKVVSSAGESARMIREMFNYAR-QPC-----IVFMDEIDAIGGRRFSELLNQLDDSLGKVKVIMATNRPDTLDPALL-RPGRLDRKEIGLPNEQSRLEILIHSNKITKHGEIFEAVVKLSDGFSADLRNVCTEAIRAEREFVIDEDFMKAVRKVGDAKRLET...................................................................................................................................................................................................................................................................................................................... 399
41 -11.400[O] KOG0652 26S proteasome regulatory complex, ATPase RPT5  ali follow..  19  169.............DYNDIGGLEKQIQELVEAIV--RPPKGVLLYGPPGTGKTLMARACAAQTNA-------------TFLKLAGPQLVQMFIGDGAKL-----VRDAFQLAK-APC-----IIFIDEIDAIGTKRFDSLLNQLDSSDERIKVIAATNRADILDPALM-RSGRLDRKEFPHPTEEARARILIHSRKMNVHPDVFEELARSTDDFNAQLKAVCVEALRRDATEVNHEDFNEGIIQVQAKKKASL...................................................................................................................................................................................................................................................................................................................... 420
42 -11.300[O] KOG2004 Mitochondrial ATP-dependent protease PIM1/LON  ali follow..  24  478...............EGHYGMKDVKERIMEFIAVNLLGKILCFHGPPGVGKTSIAKSIATALN-------------REYFRFSVGGMTDVAEIKGHRRTYVGAIQCMKKVKTENP------LVLIDEVDKIGGAGFHALLELLD-PEQNVLFICTANEISKIPGPLRDRMEMIDVSEIAHQHLIPQLRK-LATEQLKIEDSALEELIKCRESGVRNLQQHIERIFRKAALQIAEQQ...................................................................................................................................................................................................................................................................................................................................... 721
43 -11.000[R] COG0714 MoxR-like ATPases  ali follow..  19  16.................IVGKDEAIRLVLVALLSG--GHA-LLEDVPGVGKTLLAKSLARSINGKQRVQCTP----------------DLLPTD----TGTNIWNPSSREFEFLPGPAFANILLADEINRATPRTQAALLEVMEELVPHPFFVIATQNPIEYQGTF-AQLDRFALS-ISLEEVEALQKAV---RQVKLTEDLQQYLLRLVRASPRGTTALQRATQAFERDYAIDDDVKFVAPHV-------LAHRLIPASGKDPKAILQRLLDS................................................................................................................................................................................................................................................................................................ 300
44 -11.000[O] KOG0731 AAA+-type ATPase containing the peptidase M41 domain  ali follow..  17  318.............YFKDVAGCDEAKQEIMEFVHGAKIPKGALLVGPPGTGKTLLAKATA-------GESGVP--------SISGSDFMEMFVGVGPSR-----VRHLFQEAR-APS-----IIFIDEIDAIGRSTLNQLLVEMDGTTAGVVVLAGTNRPDILDKALL-RPGRFDRQTIDKPDIKGRDQIFIYLKKIKLDHEPSQRLAALTPGAGADIANVCNEAALIAAATVTMAHFESIGGLEKKNRVISKLE-----------RRTVAYHESGHAVVGWFLEHAEPLLKVTIVQYVPNENLLMTKEQLFDMTCMTLGGRAAEQVL-IGKISTGAQNDLEKVTK......................................................................................................................................................................................................................... 666
45 -11.000[O] KOG0734 AAA+-type ATPase containing the peptidase M41 domain  ali follow..  18  280.............TFEHVKGVEEAKQELQEVVEGGKLPKGILLVGPPGTGKTLLARAVA-------GEADVP--------YASGSEFDEMFVGVGASR-----IRNLFREAK-APC-----VIFIDELDSVSRQTINQLLAEMDKPNEGVIIIGATNFPEALDNALI-RPGRFDMQTVPRPDVKGRTEILWYLNKIKFDQSVPEIIARGTVGSGAELENLVNQAALKAAEMVTMKELEFLMGPERRSVEIDNKN-----------KTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSRVAEELIFGTDHITTGASSDFDNATKIAKRM............................................................................................................................................................................................................ 631
46 -10.900[O] KOG1051 Chaperone HSP104 and related ATP-dependent Clp proteases  ali follow..  23  171.....LTELARNGQLDPVIGREDEIRRTIRVLSRRTKNNPVLI-GEPGVGKTSIAEGLARRIIDDDVPAN---------------SNCKLLSLDGSKFRG-ERIKSVLKEVEESETP----ILFVDEMHLLGMDAANLLKPMLAR--GKLHCIGATTEYKK--AAFERRFQIILVKEPSIEDTISILRGLKEKHGVTISDRALVTAAHLASRYLTSAIDLVDEAAA................................................................................................................................................................................................................................................................................................................................................ 403
47 -10.800[O] KOG0729 26S proteasome regulatory complex, ATPase RPT1  ali follow..  17  173.............TYSDVGGCKEQIEKLREVVE--EPPKGVLLFGPPGTGKTLCARAVANRTDA------------------------CFIRVIGSEGEGARMVRELFEMAR-KAC-----LIFFDEIDAIGGARFDDLINQLDDPRGNIKVLMATNRPDTLDPALM-RPGRLDRKSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPN--AEIRSVCTEAIRARRKIATEKDFLEAVNKV.............................................................................................................................................................................................................................................................................................................................. 416
48 -10.700[KT] COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains  ali follow..  16  189............RDSVEIIGNSGPMLAMKADIDV-PSQFNILIHGETGVGK----ELVARTIHQRSNRKRQP-----NCAAIPE----NLLESEKGAFTGADRAR-----------MGKFALLFLDEIGELPLSAQSKILRALQN-TVDVRILAATN--RDLKKEVEAGRFRADYHRLSVYPIVEQARRKLGITQLKLHGDVLSQLIQYPPGNVRELEHVINRAALKAKARQ.......................................................................................................................................................................................................................................................................................................................................... 429
49 -10.600[T] COG2766 Putative Ser protein kinase  ali follow..  12  75..............FEEFYGMEDAIEQIVSYLKHAAQGQILYLLGPVGGGKSSLAERLKSLMQ-RSPVNDHP-IMSPWAAKRLHEFGVVKVWPSILEQIAIQDISALVGKVDIR-CRANQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGGIILAHSNESKNNEAFLDRVYIVKVPYCEEIKIYEKLLNHSELAHAPCAPGTLETLSRFSILS--ENSSIYSKMRVYDGESLTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRV--FNFDHAEVAANPVHLFYVLEQQIEREQFPQEQAERYLEFLKGYLIPKYAEFIGKEIQTAY........................................................................................................................................................................................................................................ 491
50 -10.600[R] COG4928 Predicted P-loop ATPase  ali follow..  12  29...............DDKLGYAPFAKNLAESICKMSPPDGLVIAAPWGLGKSTLLNFIIHYLKQKPEQEQNPIESFAERVSTVPGLWTKGFAATVKTVISPKDIHKLKQEIEETLKKQQKRILVIDDIDRLTAEEIRQLFRVIKA--PNVVYLLL--DKEVVIKALLEKIVQVSFRIQLSRLFDSQLDKIISGTPEELFDEIYWQGIEHFITTPRSILRLANTLYPGVKGEVNFVDFVAI.................................................................................................................................................................................................................................................................................................................................. 323
51 -10.400[O] KOG0733 Nuclear AAA ATPase (VCP subfamily)  ali follow..  18  172.............SLSDIGGLDDCINELLELVAM-HPPRGVLLHGPPGCGKTMLANALANELG------------------------VPFISISAPSGESEKKVREVFEEAK-APC-----LMFIDEIDAVTPKIVAQFLTCMDTDGKPVLVIGATNRPDSLDSALRGRFDREICLTVPSQDAREKILRTMAKGLKLSGDFDFRQLAKQTPG--ADLKALTAAA.................................................................................................................................................................................................................................................................................................................................................. 392
52 -10.300[R] COG2842 Uncharacterized ATPase, putative transposase  ali follow..  16  70.............AFIETATSRQIFKTLEFAQIANCLA---TVYGMSGVGKTKAIQEFAK-----------------------SHANVWLVTASPSRSSLSEILYEIALELGISDAKGTEGLLIVDEADHLPYEALEELRIMQEEAGIGLVLVGNDKVYTRM-ARLWSRVKNTSIQKTKKADT----QAVAQAWGLETDEEALKVMQSITEGGLRILTQTYACRNGSK.............................................................................................................................................................................................................................................................................................................................................. 281
53 -10.300[R] COG5545 Predicted P-loop ATPase and inactivated derivatives  ali follow..  11  348VLELALANSYSPDPLHAALMKRTLIAAVARAFEPGKHDEITILQGKQKSLKSTFWEILAGEEFFTDDLNGT-----DEVLKISQYWILEYAEFENSYKKK--DVSQLKAFLSRKKDSMR-RPY-----------------TDIEDFPRPSILVGTTNLDEFLYDPTGER--RFLFKKIPIKMLQQERDLIWAAAVAAYRNGEQWRLTEVEDEWLDAANK------QYQSTDTWEEAVMAWAELQKEVSVGEILSDVLKIELAKQQNRVAAILRS-HGWTRGDRKRVNGRLIRPWVRPQQEVEQEVERGVEQEVERGVEQEVEQPQALVTTDLEPECSTCSTNSPQTFPNFDSNNETAQWIAPQTAAPFVTPQETTPTEANEKSLEGQGVEQPVDEPQTQSPQVIEECSTPCFTSGSSLELSFEQKLMGNVALIRESIADQCWGTLTEEWTSEFKSAVWKELTPQERQAVKQ........................................................................................... 831
54 -10.200[L] COG0593 ATPase involved in DNA replication initiation  ali follow..  11  119.....LNTKHLFDNF--VEGKSNLARAVGQKLAQAPGEPSAFFLGGTGLGKTHLLHAIGNGI-----------------LADKPNARVLYIHANNFMQHMVKAVRD-NKMDQFKKFYRSLDALLVDDIQFFAEHIFNSLFETSDRYPKEI---------EKIEERLKSRFG--AIEPPDLETRVAILLKKAEEHNMNLPEEVAFFIAQRLRTNVRELEGALNRVKAMQGGDIDIDFVRDTLK-----------DILALQERLVTIENIQKVVAEYYRIK--VSDLKSKSRARSVTR-PRQIAMALAKELTNRSLPEIGRAFDRDH-TTVLNACREVPKFREQDNSIQEDWANLIRTL............................................................................................................................................................................................................. 452
55 -10.200[O] KOG0736 Peroxisome assembly factor 2 containing the AAA+-type ATPase domain  ali follow..  19  688.............KWDDVGGLEDVKTSILDTVQ--RKRSGVLLYGPPGTGKTLLAKAVATECS------------------------LNFLSVKGPEGESEKNVRDIFEKAR-RPC-----VIFFDELDSLAPAVVSQMLAEIDDSSQDLFIIGASNRPDLIDPALL-RPGRFD-----------KLLYVGVNADASYRERVLKALTRKFK--LSEDVS-LYSVAKKCPSTFTGADMYALCADAWFQAAKRKVSKSDSGDMPTEEDDPDSVVVEYVDFIKAMDQL..................................................................................................................................................................................................................................................................................... 949
56 -10.200[O] KOG0730 AAA+-type ATPase  ali follow..  14  238.............GYDDVGGVRKQMAQIRELVE--KPPKGILLYGPPGSGKTLIARAVANETG------------------------AFFFCINGPEGESESNLRKAFEEAE-APS-----IIFIDEIDSIAPKIVSQLLTLMDKSRAHVIVMGATNRPNSIDPALR-RFGRFDREGVPDEIGRLEVLRIHTKNMKLAEDVDLERISKDTHG--ADLAALCTEAALQCIREVSNEHFHTALGNSNPSALRETVVEVPNGGLENVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLT--MWFGESEANVREIFDKARQSAPCVLFFDELDSIATQRGNSAGDAGGAADRVLNQ.................................................................................................................................................................................. 639
57 -10.200[L] KOG2228 Origin recognition complex, subunit 4  ali follow..  10  538...STIAARLCGKSHIPLVGHMKLYQWVRQTIVLGE-GNSVIIVGPRGSGKSVLVDDILSRAA-------------------EINEKSYVVRLNGTYQTD---LREISRQLS-VMTTSAAVIFVLEEFDLFVQHSRQMLLYNLFDIAQS-ILIIGLTTRYDCSESLEKRVKRFSHMVISLSEFEQILKSVLYVSDEGGKDQIITCWNQRVDELLSDTRSHLHKLVQ-PDRPLLADEDFANISLKVSDHKVELVKNLSLLELA-LLICAVRFEARDIPFNSAYQEYRQLHQSSVINAAASGALAHSSRLWGRDVALEAWETLGSIGLIIPVH-PEVDINVVSVGLREHRRLPSHYYRWLK........................................................................................................................................................................................................... 969
58 -9.980[R] COG5271 AAA ATPase containing von Willebrand factor type A (vWA) domain  ali follow..  9 1537...............TYSLHTDTTLMNASKVLRALQVLKPILLEGSPGVGKTSLITALARETG-------------HQLVRINLSDQTDLMDLFGSDVP-----VEGGEGGQFAMRNGHW--VLLDELNLASQSVLEGLNACLDH-KAHPNFVFAAQNPKGLPRSFINRFSVVYVEALKEKDMIEIAACNYHQVNEDWRLKIIKFMFRLQD-NLRDTLRWLQLL-----NDAPKYTCVSPADYLEVMVLHRMRTVEDRVRTCELFKEVFDIDYEPRTIGFSLSSQCFKVGHSLLVRDVERQDSQNILQSQLPVLESVITCINKKWPCILVGDTATGKTCILRLLAAIAGAKIKEMAVNSDTDTMD..................................................................................................................................................................................................... 1910
59 -9.920[R] COG3903 Predicted ATPase  ali follow..  13  2...........................VQEVLTNYRL---VTLRGEGGVGKTRLAIQIAAASEFRDGL-----------VDLAPIADPGMVSTTAAHALGLIDFDTLSHAIG-----NCHMLMVLDNCHVLDACA--SILATSRESANEAIQLFTERARLVQPDAVSEICRRLDGMPLAIELAAARLRSLSPNEIANSLDDRFRLLT----GGARSTVQTLRASMDWSYALLTDTELFRRLAVFVGGFDLTAASEVAAAGRYSVLDQLTLLVDKSLVVAEESRGLLETVRQYALEKLNESEEIDGVRARHRTHYATMAAGLNVPASTDYEQRLLQAEAEI---DNLRAAFTWSR................................................................................................................................................................................................................ 363
60 -9.910[KE] COG3283 Transcriptional regulator of aromatic amino acids metabolism  ali follow..  15  202.............AFSQIIAVSAMKHVVEQARKLAMLSAPLLITGDTGTGK----DLFAYACHQASPRSAKP-----NCASIPE----DAVESEPEGKKGFFEQAN---------------SVLLDEIGEMSPRMQAKLLRFLND-HVDVRVICATQK-NVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLSADLSTVLTRYGPGNVRQLKNAIYRALTQLEGYLRPQDILLPD-DAMEGSLDDITSRFERSVLTQLYRSYPSTRKLAKRLGVSHTAIANKLREYGL............................................................................................................................................................................................................................................................................ 506
61 -9.590[G] COG3265 Gluconate kinase  ali follow..  16  3.....................................GKCIIVMGVSGTGKSCVGQALALALGAK--IDGDDLHPRANIQKMAAGQPLNFLVCSALKKQYRDRLREGNEGIRFLWLTGDYDLVL-RAGHFMPESLLKSQFATLEAP-PDVIPIDISSSIADVVEHCIAALSL...................................................................................................................................................................................................................................................................................................................................................................................................... 168
62 -9.440[F] COG1618 Predicted nucleotide kinase  ali follow..  11  2.............................RIEGKEKTMLRIAVTGSPGVGKSTVVAKTAEKLAEKPGFKIG---RTAEIRKEGHREGFSIRDLATGKTGILSHVKGSGPRANAVRNALACDLVVIDEIGPMESQSFVSAVEEVLESDKPVLAVLHHSSRHPLAQRFRKGFEVLTVDKGNRDELPEKITNRFLR................................................................................................................................................................................................................................................................................................................................................................................. 181
63 -9.100[KL] KOG1123 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, 3`-5` helicase subunit SSL2  ali follow..  12  336....................QEKSLRKMFGNGRARS-----VIVLPCGAGKSLVGQQFKMWSTADDSMICRFTSE----KDKPMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQ--EWGIMVLDEVHTIPAKMFRRVLTIVQ--SHCKLGLTATLLREDLNFLIGPKLYEANWLELQKKGYIARVQCAEVWCPMSPEFSKKMLLYVMNPSKFRSCQFLIDKTIVFSDNVFALKHYAIKMGPTSQNERIQILQNFKFNSKVNTI-FVSKVADTSFDLPEA---------NVLIQISSHGGSRRQEAQRLGRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKRQRFLV................................................................................................................................................................................................................... 697
64 -9.080[R] COG1203 Predicted helicases  ali follow..  13  4............KAFRKLTGQKEAMDNLLE-------GKSLIIRAPTGAGKTEASLIPFIYGLNDYLPPQ-PTRTLVESIGERAIKYASFKKLRVAIHHGVTTIDQTAGAYLSVPLSMPKRLTVFDEVHTLDPEKGLQTAAAIAM--LPSIIMSAT-----LPDVFIERVKERIEKNGGKVEIMDKVELINRPDEMLTADTVLKEAENCRKNTVERAQNLYLDLRKKIDYPIFL---SRYLEKDRAEKEKSFEKVFGKNGKGECIFISTQVIEVGMDIS-----------PIILSEVAPIDALIQ................................................................................................................................................................................................................................................................. 330
65 -9.030[KT] COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain  ali follow..  15  214.............VLGDMLGQSPQMEQVRQTILLARSSAAVLIEGETGTGKELAAQAIHRE-DARQGKKSHP-----NCGAIAE----SLLEAEGSRRGGRAGLFEIAHG-----------TLFLDEIGEMPLPLQTRLLRVLEE-PVDVRVISATH--CNLEEDMRQGQFRRDL-RLQLPPLRERVADIFSAALRQGLQASETVLVHYDPGNIRELRNMMERLALFLSVEPTPDLTPQFLQLLLPEL-ARESAKIPAPRLLTPQQALEKFNGDKTAAANYL........................................................................................................................................................................................................................................................................................ 515
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.