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Query: gi|11497099|ref|NP_051176.1| hypothetical protein (BB_P15) [Borrelia burgdorferi B31], from B.burgdorferi

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSDKFTIKFKGILDHAATKKAIEQDISKMEKYLKPKKSSLGSTKDIVKNNLSDKKKELSRQSKFESLRERVEKYRLTQTKKLIKQGMGFEKARKEAFRRSLMSDRDKRRLEYKELAKESKAKSKMLAASQGKGLVAKIAIGSALGNIISNAMSKVGGGLLGFAKKAVEEDTKTKRTQLLNKAFYGDPKEKEGLLKIIGGMKGFERDLEKEEFLNQASVFKGTLRDLDMLNETNLKNAVEFAAMLKSSGAMSSEDAVKAVNSVLGGDGSELFDLLKKSGVGDKYIEDAKMAWQSGAQVDLESRITKMMEMFEDFKSFGLTKKVNNAESIQSNLASAEQTLQNLTTTVLDPLLDLINKITNYFKDFAFETHIINPIINGIKSIFNLNYFFAKLKSMLPGWMGGDEGAALKKLQEEIQNQDNANSTPLast
1 -13.100[S] COG5280 Phage-related minor tail protein  ali follow..  10  1MAKKITIAINGLKDIGKQSNSVNSELRDVERLLKLNPNNVELVAQLLSKQVELTTKKLDGLKGAQADVDRQFKSGDIGEEQYRAFQREVVATEGRL--DHYKQSLKDVESSSGEAGNATKGLGGKFDELGQSVEDVGEAVKGGVLMEAADHLSVVGDKLKEFSGSAQEAFSDVDEGMDKITTTTGKASDEFKTQFDNIISSMAVDSFE--DVGSALGTLSAQFDMSG----DTLEKNSKLALQYANINDTDVKTSIESAKSAIEAYGLSNKDFSTVLDSVTATSQRTGVAVDSFDSAVKGAPQIKDLGLNFSQGTELLGQFSKAGVDGDAALSSLSKASIIYAKG-NKSLSEGLGETIEKIKNAKTKQEALTEAATVFSRMVDAIQRGAFNLSELGDVAKKSNGTISDTFNKTVDDIDEQQIA. 434
2 -12.300[R] COG3941 Mu-like prophage protein  ali follow..  9  1.........................................................MARNLRASLIVDLLGNIKSRQWSQELGAFSRSGQAGLGGLGNAARRAGQETDVLGSRMQRTLAGVRGSIRHVTSDFDRLQGSITGTIGRISN-GMLAGGAAVYGFNRGFIRPAAEMETYMIRLNSLYKGDRAKTDDVRRWAIQNAKETTWGLAGVMQEYTSSLGF-------SDREARNFVTMLQDQGAVGGWSLSDQMYARGSIQAADANILATYGINAYRVLADRLGVDQKVVRKLGEKGLLGPDSIRLLFQTLAEQARGAQKDAMNSWSGLTAMMGDVWDQFARDVMDSLKGNLRGFLSWVDSAKLAESTASAMNQGFEYARDAVTGFYQAIRKVRDTLQALRDAGYGD............... 371
3 -7.790[S] COG5412 Phage-related protein  ali follow..  9  2............................................................................................ADYTLTAKLTADPSGFRAGFQKAQESLANLQSRVNQTGKRVQSIGKSISDLGSKLTRNITVPAVGAATALTSITLVKGVGIDSARAKLKGLGHDAEAIDSIMDSALASVKG-TAFGLDEAATTAANAVAA----GIPPGKELTRYLSLTADTAAIAGTSLGEIGAILNKVTTSGRAYNSELQMLSDRGLPVYQWLAEEANTTADFDMASKGEISTDMLLNAIEKNIGGAAKIEESFSAAIANIGADIARIGANFLDAG--------------GKAGGFFSTVKPLLTEFRGFLAQVEEQAADWGVAFGQAFNNVIDRVRELKSWFDGLSPS. 321
4 -7.640[S] COG1511 Predicted membrane protein  ali follow..  8  109IPEDFSKNASTVLDKNPKKLDLKYHTNAGSNYVGATIG--EKAIDKLKASVSKEVTEQYTKVIFDNFKDIAKGLSDASSGKKIDDGTKDAKNGSAQLKENLAKLKESTATISDKTAQLADGAAQ-VTSGIQSLDSSLGKFQDSSNQILAAGSGELTSKMNELLAGLQNVQKGTPNLTNGLDQLNSKVQEGSEKAAKAEKIINALDLTKLETAVNNLEKSETAMKEFKKQLTDFENSLKNRDQAFKNVINSSDFLTAEQKSQLINSVEKKLPQVDAPDFDQILSQLPTADQLPDIATIKSSLEDVKAQVAQVKAMPEATSKLYNGAKTIQDAIDRLTEGADKIYNGSQK-LTDGQTKLTAGIGEYN---KQFAKAKAGSEQLVTGSSQVSGGLFKLLDGSKQVQSGSSKLADGSASLDTGLGKL. 531
5 -6.620[D] COG4477 Negative regulator of septation ring formation  ali follow..  7  127IRQGVAQLVEQEKRNSNKIQESLDLYDNLRSDIADNADLYGTVITELEKHLANIETEFSQFVTLNSTGDPIEAAEAEEHTIALRAITEQIPSFIKTIEKDVPKRLEELQEASDKFVAEEYILPDNVNERMDDLHDHLVESSSLLEQFELDRVEAELGLIQEKVEELYAIFEREYSARRNVEKRSSVLKEYIEHIRANNKNLLLEID-YVRGYQEHLESLDSDVDEILGNIQAKTMPYSILSRRVN-----SVVNALEDIEKNQIKISDTLTGLRDEERAAQEIAERFDSELRTIKRYVEKCNLPGLPKDYLDLFFTTGDRVQNNIDTINHLVDVSTEDMHVLKEATTNLTAVLAEQLIQYANRYKAANEQVAQGISRALQLFENSRDYDGSFDEISKTLELVEPGAASRISGVYFKNKPTPDY. 575
6 -6.300[U] KOG4809 Rab6 GTPase-interacting protein involved in endosome-to-TGN transport  ali follow..  10  394MERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKF----MKNKIGQVKQELSRDTELLALQTKLETLTNQFSDEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQD-MAEEKGTQAGEIHDLKDMLDVKERK-VNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL--------EEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEK--SEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEIL.............................................................................. 737
7 -6.050[U] KOG0946 ER-Golgi vesicle-tethering protein p115  ali follow..  9  652...........VTHYKNMIREQDLQLEELRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGA--QMNGIQPEEIGRLREEIEELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDS---EQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAFAKSVEVQ--------GETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTA-----IKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLADQDQKILSLKNKLKD--LGHPVEEEDELESGDQEDEDDESEDPGKDLDHI.................................................................................. 962
8 -5.980[D] COG5185 Protein involved in chromosome segregation, interacts with SMC proteins  ali follow..  8  238LVRTYHLYLDESPEESEPEKELKATFNQQNQDLYNQTEALKSTNEELINQIKSAEELDSAIQVLEERYRTMQR-DEVKFQSAMSGMKSKMESRTNLM-KQLQVNIEEKESQLQLLKEKRDSLKYQVE-NQDISISEFEKMVSEREQL-DRNLNMIGSKISELRKEVFDTDLLIQASIDSLEKKVQKFNSLAYRIGIVPIAAIRSANNDFE--LDLKNKVRPFINEVRRSITLEFHEEQNKSLKL--------QEHVDTVNDLIAELQDELRGIESRLTSVLSECNMLRETASEEKNAFDAESDKLERELLKLSSHNSMLQLDQRIQSINIEADQIAHACMEYKNNIYKEVAFVLGEIIHFKLHVQ-------------DSLEDLKMDYQKELDDLSR........................... 621
9 -5.760[D] KOG4438 Centromere-associated protein NUF2  ali follow..  7  102..NDFETA-----D-CPKAKRTSRFLSGIINFIHFREACRETYMEFLWQYKSSADKMQQLNAAHQEALMKLERLDSVPVEE--QEEFKQLSDGIQELQQSLNQDFHQKTIVLQEGNSQKKSNISEKTKRLNELKLLVVSLKEIQESLKTKIVDS------KLKNYKEKMKDTVQKLKNARQEVVEKYEIYGDSVDCLP-----SCQLEVQLYQKKIQDLSDNREKLASILKESLNLEDQIESDESE---KKLKTEENSFKRLMIVKKEKLATAQFKINKKHEDVKQYKRTVIEDCNKVQEKRGAVYERVIKLGIQQLKDAAEREKLKSQEIFLNLKTALEKYHDGIEKAAEDSYAKIDEKTAELK........................................................... 456
10 -5.720[S] COG5283 Phage-related tail protein  ali follow..  8  1MADI-SVTTGIDLNETKAINRLKSAVKDSTREWQINEAQAKSAVSASKYRYEGLSEAMEKQKYIANLSEGMKTINRNTDAQKYNAQLTTAERSLASMTGQLNRAKEYQQTGIEDLNKSLSANDKLMQSQIDLYEKTRNKMGAAKAEVQTEIYRAQVTELKRLEAAEGTSSETLVKQKTRVNEAASSLMNYRNKLLEANLA---QPFNSESLIGKGLNTVYQTTEKATDVMAAGYQKVKSAAYQSAFG-ASELQNQYKTTFNLLVT-QEQGSELSVKYGKTQKEIADGYQELIK-RGYTSSQALAALPTML-QASVASGDDFTDVVHNSTAALESFGMRSNDVAG-----MTKNTKEAVNQMAYAADMTA-FQNMGVAMEYVGASAHQSKLSLSETASAIGILSNNGLEADKAGTGLRKVIVSL. 471
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Jaroszewski L, Godzik A. Tolerating some redundancy significantly speeds up clustering of large protein databases. Bioinformatics. 2002 Jan;18(1):77-82.