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Query: gi|29345424|ref|NP_808927.1| two-component system histidine kinase with response regulator receiver domain BT_0014 [Bacteroides thetaiotaomicron VPI-5482], from B.thetaiotaomicron

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLILLLGFIIYLFRGERMKRDELKWEMKELGIIRDLTRKTYGHLLELASQGEVVSTWSESDLRLYRERREKTCGVLKELQQFVHTPEQQERIDSLCLLLEQKEMLLSAAMSTFDELENIGETVGEKVPAIVRQVRRQPTRNILAPAVKEAYAGTATTGEEQPEKKKSFLKKVFGGKEKKSAYRQQREQQRAASEKVPSSTTRNSGNNAAVHLLHALSREVTEKQKEQREKLSAQMDSLHLSSRALNKRLNGLVGDFDKVAGERLETRYNAIAADREKSYNTAATLALFVFLLAIVLYTLLHRDVNRCLRYRRELESSDLKNKELLQSRKNMMLTIAHDLRAPLTAIKGYAELLPGEVDEKRKDEYAVHIVRSSDYMIGLVNSLIEFYLLDAGKGKMNVTVFRPLSLFDEIVKLHTPSVRKEGLTLCTDFEGLDTVVEGDRPRIMQIANNLLSNAIKFTRKGKISLQAAYGQGELRFSVQDTGPGMTEDEQKRIFRAFERLDNARYLPGFGLGLAIVSRLTELLGGRITVESPYGTGSLFRVALPLSEVAKHGEDGENGYAEDYGLEGTYVLVIDDDRIQLDITRRMLVRNKVRCECCRTVRELMAALRERTYDLLLSDIQMPDMDGYRILDLLRSSNMENARTIPVLAVTACADDEEHYISFGFAGCLRKPFSMDELISTVSRMVVKTGKKEPDFSFILSGEKDKGRMLDIFIRETEESIHTLENALCGHDRDTIHKVLHKNLPLWETVRMNFPMARLRGLVTHTAAVWEERQYMEVGEIIHAAEKLAESARKIRESIDEEHTDYRGLast
1 -59.9004q20_A mol:protein length:268 Sensor protein DivL  ali model follow..  26  6...........................................................................................................................................................................................................................................................................................................SGLVPRGSHMLQSALADRSAALAEAERLKRDFVGNVSYELRTPLTTIIGYSELLERDGISERGRNHVAAVRAAATQLARSIDDVLDMAQIDAGEMALEIEDIRVSDLLLNAQERALKDAQLGGVTLAVECEEDVGLIRGDGKRLAQTLDHLVENALRQTPPGRVTLSARRALGEVRLDVSDTGRGVPFHVQAHIFDRFVG----RDRGGPGLGLALVKALVELHGGWVALESEPGNGSTFTCHLPETQQPGAMQPELG.......................................................................................................................................................................................................................................................... 261
2 -58.2002ayx_A mol:protein length:254 Sensor kinase protein rcsC  ali model follow..  19  1.................................................................................................................................................................................................................................................................................................................................................................................................................................................................MGGSGVEGLSGKRCWLAVRNASLCLETSLQRSGIVVTTEGQEPTPEDVLITDEVKKWQGRAVVT-FCRRHIGIPGEWVHSVAAPHELPALLARIYLIEMESDDPANALPSTDKSDNDDMMILVVDDHPINRRLLADQLGSLGYQCKTANDGVDALNVLSKNHIDIVLSDVNMPNMDGYRLTQRIRQLG----LTLPVIGVTANAEEKQRCLESGMDSCLSKPVTLDVIKQTLTLYAERVRKSRDS................................................................................................................. 254
3 -56.2004jas_A mol:protein length:258 Histidine kinase  ali model follow..  28  1......................................................................................................................................................................................................................................................................................................VENVTESKELERLKRID--------------RMKTEFIANISHELRTPLTVIKGYAEMIYNELDLSTLKEFLETIIEQSNHLENLLNELLDFSRLERKSLQINREKVDLCDLVESAVNAIKEFASSHNVNVLFESNPCPVEAYIDPTRIRQVLLNLLNNGVKYSKKDAVKVILDEKDGGVLIIVEDNGIGIPDHAKDRIFEQFYRVDSTYEVPGTGLGLAITKEIVELHGGRIWVESEVGKGSRFFVWIPKDRAGEDNRQDN........................................................................................................................................................................................................................................................... 258
4 -55.0005uht_A mol:protein length:259 Sensor histidine kinase  ali model follow..  27  1.....................................................................................................................................................................................................................................................................................................MVENVTESKELERLKRID--------------RMKTEFIANISHELRTPLTAIKAYAETIYNSLGESTLKEFLEVIIDQSNHLENLLNELLDFSRLERKSLQINREKVDLCDLVESAVNAIKEFASSHNVNVLFESNPCPVEAYIDPTRIRQVLLNLLNNGVKYSKKDAVKVILDEKDGGVLIIVEDNGIGIPDHAKDRIFEQFYRVDSTYEVPGTGLGLAITKEIVELHGGRIWVESEVGKGSRFFVWIPKDRAGEDNRQDN........................................................................................................................................................................................................................................................... 259
5 -50.7004u7n_A mol:protein length:277 Histidine protein kinase sensor protein  ali model follow..  24  2..............................................................................................................................................................................................................................................................................................GSSSSGLVPRGSAEFHDVTEQQKID--------------NDRKQFVSNVSHELRTPLTSLRSYIEALSDGAWKDPEPGFLKVTQEETDRMIRMINELLSLSRMDSGTTRVDMELVNINEMFNYVLDRFDMILKKKYYTIKREFTKRDLWVEIDTDKFTQVLDNIMNNAIKYSPDGVVTCRLLETHNQVIISISDQGLGIPRADLGHVFDRFFRVDKSRAQGGTGLGLAISKEVVQMLGGRIWVDSVEGKGSTFYISLPYEPYEEEDLWDDDSQA....................................................................................................................................................................................................................................................... 271
6 -49.4004pl9_A mol:protein length:183 Ethylene receptor 1  ali model follow..  32  2.......................................................................................................................................................................................................................................................................................................................................................................................................GSLQLELGTFNLHTLFREVLNLIKPIAVVKKLPITLNLADLPEFVVGDEKRLMQIILNIVGNAVKFSKQGSISVTALVTKSDLRVKVKDSGAGINPQDIPKIFTKFAQTQATRSSGGSGLGLAISKRFVNLMEGNIWIESDGGKGCTAIFDVKLGISERSNE.............................................................................................................................................................................................................................................................. 183
7 -46.2003jz3_A mol:protein length:222 Sensor protein qseC  ali model follow..  23  2.......................................................................................................................................................................................................................................................................................................................................ERRFTSDAAHELRSPLTALKVQTEVAQLSDDDPQAKKALLQLHSGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSSVMDIYHTAQQAKIDVRLTLNAHSIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVDVTLN----ADNFIVRDNGPGVTPEALARIGERFYRPPGQTA-TGSGLGLSIVQRIAKLHGMNVEFGNAEQGGFEAKVSWL....................................................................................................................................................................................................................................................................... 215
8 -45.3003mm4_A mol:protein length:206 Histidine kinase homolog  ali model follow..  22  1..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GSSSSGLVPRGSHMASTDS----ESETRVKSVRTGRKPIGNPEDEQETSKPSDDEF--LRGKRVLVVDDNFISRKVATGKLKKMGVEVEQCDSGKEALRLVTELPFDYIFMDCQMPEMDGYEATREIRKVEKSYGVRTPIIAVSGHDEEARETIQAGMDAFLDKSLN--QLANVIREIESKRHLE.................................................................................................................... 194
9 -45.2004i5s_A mol:protein length:450 Putative histidine kinase CovS; VicK-like protein  ali model follow..  17  83...............................................................................................................................................................................RLTHENLAQEKNRLTSILSYMTDGVLATDRSGKITV----INDMAQKQLNVTREQALECNILDILDDDSYTYNDLITKTP---------EIVLTRRDEYDEFITLRIRFALNRRESGFISGLIAVLHDATEQEKEE--------------RERRLFVSNVSHELRTPLTSVKSYLEALDDGALTESVPSFIKVSLDETNRMMRMITDLLSLSRIDNQTSHLDVELTNFTAFMNYILDRFDQIQSQQSTNKVYEIPDKSVWIEIDTDKMTQVIDNILNNAIKYSPDGKVTITMQTTDTQLILSISDQGLGIPKKDLPLIFDRFYRVDKSRAQGGTGLGLAIAKEIVKQHKGFIWANSEEGEGSTFTIVLPYENDNDAIDEWEEDEDES..................................................................................................................................................................................................................................................... 450
10 -41.4004biu_A mol:protein length:298 SENSOR PROTEIN CPXA  ali model follow..  21  37..................................................................................................................................................................................................................................................................................................QGNLRQHPELEAGPQEFLAAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRSGESKE---LERIETEAQRLDSMINDLLVMSRNQQKN-ALVSETIKANQLWSEVLDNAAFEAEQMGKSLTVNFPPGPWPLYGNPNALESALENIVRNALRYSHTK-IEVGFAVDKDGITITVDDDGPGVSPEDREQIFRPFYRTDEARD-GGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIWLPLYKRS.................................................................................................................................................................................................................................................................. 292
11 -40.2003sl2_A mol:protein length:177 Sensor histidine kinase yycG  ali model follow..  26  1..............................................................................................................................................................................................................................................................................................................................................................................................................MWIQIVRFMSLIIDRFEM-TKEQHVEFIRNLPDRDLYVEIDQDKITQVLDNIISNALKYSPEGGFSIDVNEEEELLYISVKDEGIGIPKKDVEKVFDRFYRVDKTRKLGGTGLGLAIAKEMVQAHGGDIWADSIEGKGTTITFTLPYKEEQEDDWDEAENLY....................................................................................................................................................................................................................................................... 166
12 -38.7001ys3_A mol:protein length:150 Sensor-type histidine kinase prrB  ali model follow..  22  2..........................................................................................................................................................................................................................................................................................................................................................................................................SDDHVPVDITDLLDRAAHDAARIYPDLDVSLVPS----TCIIVGLPAGLRLAVDNAIANAVKHGGATLVQLSAVSSRAGVEIAIDDNGSGVPEGERQVVFERFSRGSTASH-SGSGLGLALVAQQAQLHGGTASLENSPLGGARLVLRLPGPS.................................................................................................................................................................................................................................................................... 150
13 -38.5003a0r_A mol:protein length:349 Sensor protein  ali model follow..  19  3.....................................................................................................................................................................................VEHLRNFSESILESLETAIITLSKDGRIT----EWNKKAEQLFGLKKENVLGRRLKDLPDFEEIGSVAESVFEN---------KEPVFLNFYKFGERYFNIRFSPFRNAKTQLEGVIITIDDVTELYKYEEERKRRERLS-----ILGEMTARVAHEIRNPITIIGGFIMRMKKHDDPETLKKYINIITNELSRLETIVKEILEYSK----RQVLEFTEFNLNELIREVYVLFEEKIRKMNIDFCFETDNEDLRVEADRTRIKQVLINLVQNAIETGENGKIKITSEDMYTKVRVSVWNSGPPIPEELKEKIFSPF-----TTKTQGTGLGLSICRKIIE--GGKIWTENR-ENGVVFIFEIPKTPEKR................................................................................................................................................................................................................................................................. 349
14 -38.5006blk_C mol:protein length:158 Signal transduction histidine-protein kinase/phosphatase mprB  ali model follow..  23  2.........................................................................................................................................................................................................................................................................................................................................................................................................AMVVHEPVDMTEVIDRSLERVRRRRSDIEFEVTVT----PWQVIGDSSGLGRAVLNVLDNAAKWSPPGRVGVRLQIDPGHAELVITDQGPGIPPQERHLVFERFFRSASARSMPGSGLGLAIVKQVVLKHGGALRVDAAQPPGTAIHIVLPGRPM................................................................................................................................................................................................................................................................... 158
15 -38.5003m6m_D mol:protein length:143 Sensory/regulatory protein rpfC  ali model follow..  22  2..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SNPFLRHRARVRSMRMLVADDHEANRMVLQRLLEKAGHKVLCVNGAEQVLDAMAEEDYDAVIVDLHMPGMNGLDMLKQLRVMQASGMRYTPVVVLSADVEAIRACEQAGARAFLAKPVVAAKLLDTLADLAVSTRQLAT.................................................................................................................. 142
16 -37.7004euk_A mol:protein length:153 Histidine kinase 5  ali model follow..  21  1...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GSHMETSKPKILLVEDNKINIMVAKSMMKQLGHTMDIANNGVEAITAINSSSYDLVLMDVCMPVLDGLKATRLIRSYEETGNNRLPIIAMTANTESSEECYANGMDSFISKPVTLQKLRECLQQYL.......................................................................................................................... 152
17 -37.6004kp4_A mol:protein length:236 Osmolarity sensor protein EnvZ, Histidine kinase  ali model follow..  24  2.............................................................................................................................................................................................................................................................................................................................AAGVKQLADDRTLLMAGVSHDLRTPLTRIRAYAETIYNSLGESTLKELAESINKDIEECNAIIEQFIDYLRTGQEM---PMEMADLNAVLGEVIA----AESGYEREIETALYPGSIEVKMHPLSIKRAVANMVVNAARYG-NGWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVRGDSARTISGTGLGLAIVQRIVDNHNGMLELGTSERGGLSIRAWLPVPVTRAQGTTKE........................................................................................................................................................................................................................................................... 235
18 -37.3004gcz_A mol:protein length:385 Blue-light photoreceptor, Sensor protein fixL  ali model follow..  16  2..............................................................................................................................................................................ASFQSFGIPGQLEVIKKALDHVRVGVVITDPALE-DNPIVYVNQGFVQMTGYETEEILGKNCRFLQGKHTDPAEVDNIRTAL--QNKEPVTVQIQNYKKDGTMFWNELNIDPMEIEDKTY--FVGIQNDITEHQQTQARLQELQSELVHVSRLSAEMASALAHELNQPLAAISNYMKGSRRDPNTPKVESALDRAAEQALRAGQIIRRLRDFVA----RGESEKRVESLSKLIEEAGALGLAGAREQNVQLRFSLDPGADLVLADRVQIQQVLVNLFRNALEAMAQSELVVTNTPADDMIEVEVSDTGSGFQDDVIPNLFQTF-----TTKDTGMGVGLSISRSIIEAHGGRMWAESNASGGATFRFTLPAADENLE................................................................................................................................................................................................................................................................ 377
19 -36.3003d36_A mol:protein length:244 Sporulation kinase B  ali model follow..  19  2..........................................................................................................................................................................................................................................................................................................................PHMVIRAEKMEAV-THLAASISHEIRNPLTAARGFIQLIEEQPLADKRRQYARIAIEELDRAEAIITDYLTFAKPAPETPE----KLNVKLEIERVIDILRPLANMSCVDIQATLAPF--SVIGEREKFRQCLLNVMKNAIEMPNGGTLQVYVSIDNGRVLIRIADTGVGMTKEQLERLGEPY----TTKGVKGTGLGMMVVYRIIESMNGTIRIESEIHKGTTVSIYLPLASSPSSSTISDKEKQLFAAL.................................................................................................................................................................................................................................................. 244
20 -36.3003cgy_A mol:protein length:157 Virulence sensor histidine kinase phoQ  ali model follow..  21  1........................................................................................................................................................................................................................................................................................................................................................................................................SVLLSRELHPVAPLLDNLISALNKVYQRKGVNISMDISP-EISFVGEQNDFVEVMGNVLDNACKYC-LEFVEISARQTDDHLHIFVEDDGPGIPHSKRSLVFDRGQRADTLR--PGQGVGLAVAREITEQYAGQIIASDSLLGGARMEVVFGRQHPTQKEE.............................................................................................................................................................................................................................................................. 157
21 -35.6004mt8_A mol:protein length:102 Ethylene response sensor 1  ali model follow..  14  8........................................................................................................................................................................................................................................................................................................LEESMHARDQLMEQNFALDKARQEAEMAVHARNDFLAVMNHEMRTPMHAIISLSSLLLETELSPEQRVMIETILKSSNLVATLISDVLDLSRLE................................................................................................................................................................................................................................................................................................................................................................................................................................. 101
22 -35.5003c97_A mol:protein length:140 Signal transduction histidine kinase  ali model follow..  20  2..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SLEPSQIMPLSVLIAEDNDICRLVAAKALEKCTNDITVVTNGLQALQAYQNRQFDVIIMDIQMPVMDGLEAVSEIRNYERHNTKRASIIAITADTIDDDR--GAELDEYVSKPLNPNQLRDVVLTCHSEGAE..................................................................................................................... 133
23 -35.3001m5t_A mol:protein length:124 cell division response regulator DivK  ali model follow..  26  1......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TKKVLIVEDNELNMKLFHDLLEAQGYETLQTREGLSALSIARENKPDLILMDIQLPEISGLEVTKWLKED--DDLAHIPVVAVTAFAGDEERIREGGCEAYISKPISVVHFLETIKRLLERQPA..................................................................................................................... 124
24 -34.8001dcf_A mol:protein length:136 ETR1 PROTEIN  ali model follow..  20  3..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SNFTGLKVLVMDENGVSRMVTKGLLVHLGCEVTTVSSNEECLRVVSH-EHKVVFMDVCMPGVENYQIALRIHEKFTQRHQRPLLVALSGNTSTKEKCMSFGLDGVLLKPVSLDNIRDVLSDLLEPRVLYE................................................................................................................... 134
25 -34.8001id0_A mol:protein length:152 PHOQ HISTIDINE KINASE  ali model follow..  23  1.............................................................................................................................................................................................................................................................................................................................................................................................................RELHPVAPLLDNLTSALNKVYQRKGVNISLDISP-EISFVGEQNDFVEVMGNVLDNACKYC-LEFVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLR--PGQGVGLAVAREITEQYEGKIVAGESMLGGARMEVIFGRQHSAPKDE.............................................................................................................................................................................................................................................................. 152
26 -34.5004cti_A mol:protein length:273 OSMOLARITY SENSOR PROTEIN ENVZ, AF1503  ali model follow..  23  34................................................................................................................................................................................................................................................................................................................DEIGILAKSIERLRRSLKQLADDRTLLMAGVSHDLRTPLTRIRLATEMM-----SEQDGYLAESINKDIEECNAIIEQFIDYLRTGQEM---PMEMADLNAVLGEVIA----AESGYEREIETALYPGSIEVKMHPLSIKRAVANMVVNAARYGN-GWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVRGDSARTISGTGLGLAIVQRIVDNHNGMLELGTSERGGLSIRAWLPVPVTRAQGTTKE........................................................................................................................................................................................................................................................... 272
27 -34.2001oxb_B mol:protein length:134 SLN1  ali model follow..  23  1......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SVKILVVEDNHVNQEVIKRMLNLEGIEIELACDGQEAFDKVKEENYNMIFMDVQMPKVDGLLSTKMIRRDL---GYTSPIVALTAFASNIKECLESGMNGFLSKPIKRPKLKTILTEFCAAYQGKKNN................................................................................................................. 133
28 -33.6003i42_A mol:protein length:127 Response regulator receiver domain protein (CheY-like)  ali model follow..  19  1....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MSLQQALIVEDYQAAAETFKELLEMLGFQADYVMSGTDALHAMSTRGYDAVFIDLNLPDTSGLALVKQLRAL--PMEKTSKFVAVSGFANDLGKEACELFDFYLEKPIDIASLEPILQSIEG......................................................................................................................... 121
29 -33.0003kht_A mol:protein length:144 Response regulator  ali model follow..  19  2...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SLRSKRVLVVEDNPDDIALIRRVLDRKDIQLEFVDNGAKALYQVQQAKYDLIILDIGLPIANGFEVMSAVRKP--GANQHTPIVILTDNVDRAKQCMAAGASSVVDKSSNNGRIYAIFSYWLTVNHCQE................................................................................................................... 137
30 -32.8002e0a_A mol:protein length:394 Pyruvate dehydrogenase kinase isozyme 4  ali model follow..  11  75...........................................................................................................................................................................................................................................................................................................YIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQGIIEYKDACTVDPVTNQNQYFLDRFYMNRISTRMLMNQHILIQTGNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQY-TQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIEKNKSAFKHYQMSSEADDWCIPSREPKNLAKEVAM............................................................................................................................................................................................................................. 394
31 -32.4005kbx_B mol:protein length:218 Osmolarity two-component system protein SSK1  ali model follow..  19  1..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TTSEKVFPKINVLIVEDNVINQAILGSFLRKHKISYKLAKNGQEAVNIWKEGGLHLIFMDLQLPVLSGIEAAKQIRDFEKQNGAPVIIVALTASNMDKRKALLSGCNDYLTKPVNLHALSKKITEWG.......................................................................................................................... 153
32 -32.0001jm6_A mol:protein length:407 Pyruvate dehydrogenase kinase, isozyme 2  ali model follow..  11  88...........................................................................................................................................................................................................................................................................................................YVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSNQNQYFLDRFYLSRISIRMLINQHTLIFDGSTNNCSVSDVVKDAYDMAKLLCDKYYMASPDLEIQEVNATNTQPIHMVYVPSHLYHMLFELFKNAMRATVESHIKIMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVEKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS............................................................................................................................................................................................................................... 407
33 -31.9001y8n_A mol:protein length:419 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3  ali model follow..  12  91...........................................................................................................................................................................................................................................................................................................YMQSFLELLEYENKSPEDPQVLDNFLQVLIKVRNRHNDVVPTMAQGVIEYKEKFGDPFISTNIQYFLDRFYTNRISFRMLINQHTLLFGGDTNTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAKADKPIQVVYVPSHLFHMLFELFKNSMRATVELYVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMYSTTRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKA--LSSESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKAKQ...................................................................................................................................................................................................................... 413
34 -30.9002q8f_A mol:protein length:407 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1  ali model follow..  13  109...........................................................................................................................................................................................................................................................................................................FTDTVIRIRNRHNDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSISIRMLLNQHSLLFGGKGKGSPSHRKHIGSINPNCNVLEVIK----------DGYENARRLCDLYYINSPELELEELNAKSGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKA--LSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRS........................................................................................................................................................................................................................ 406
35 -30.9004v25_A mol:protein length:408 [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 2, MITOCHONDRIAL  ali model follow..  11  89...........................................................................................................................................................................................................................................................................................................YVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSNQNQYFLDRFYLSRISIRMLINQHTLIFDGSTNPCNVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANKQPIHMVYVPSHLYHMLFELFKNAMRATVESHIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLK--ALSTDSVERLPVYNKSAWRHYQTIQEAGDW-CVPSTEPKNTSTYRVS...................................................................................................................................................................................................................... 408
36 -30.2003grc_A mol:protein length:140 Sensor protein, Kinase  ali model follow..  20  8........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RILICEDDPDIARLLNLMLEKGGFDSDMVHSAAQALEQVARRPYAAMTVDLNLPDQDGVSLIRALRR--DSRTRDLAIVVVSANAREGENSQPLAVSTWLEKPIDENLLILSLHRAIDNMAEGKE.................................................................................................................. 133
37 -30.0005t3y_A mol:protein length:125 Two-component system response regulator  ali model follow..  20  4........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TILAIDDSATMRALLHATLAQAGYEVTVAADGEAGFDLAATTAYDLVLTDQNMPRKSGLELIAALRQL--SAYADTPILVLTTEGSDAFKARDAGATGWIEKPIDPGVLVELVATLSEPAAN..................................................................................................................... 125
38 -30.0004r3a_A mol:protein length:352 Blue-light-activated histidine kinase 2  ali model follow..  17  2...............................................................................................................................................................................EFKGLMAVGLAEHDKEAWGRLPFSLTIADISQD--EPLIYVNRAFEQMTGYSRSSVVGRNCRFLQGEKTDPGAVERLAKAIRN--CEEVEETIYNYRADGEGFWNHLLMGPLEDQDEKCRYFVGIQVDMGQSESPDRATE------------LDRQLAEVQHRVKNHLAMIVSMIRIQSSQA--GGVGSQFDSLSRRVEAL-QLLYQEMDIAG----AAKATDKIIPLGAYLGRIASAINHIDGRGAIKVNVQADTVDVPV-ETAGRIGLLVSEVLTNALQHAASGVVQLRSSVMSGQLRVTVEDDGRGIPEDCDWP--------------NEGNLGSRIVRQLVQGLGAELNVTRG-GTGTIVNIDIPLSQQKTLIADERTK......................................................................................................................................................................................................................................................... 351
39 -29.9004h60_A mol:protein length:120 Chemotaxis protein CheY  ali model follow..  24  4........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KVLAVDDSISIRQMVSHTLQDAGYEVETAADGREALAKAQKARFDVIISDVNMPVMTGFEFVKAVRM--QSQYKFTPILMLTTETSPKQEGKAVGATGWLVKPFNPETLLKTLQRVL.......................................................................................................................... 120
40 -29.8003c3m_A mol:protein length:138 Response regulator receiver protein  ali model follow..  25  1....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MSLYTILVVDDSPMIVDVFVTMLERGGYRPITAFSGEECLEALNATPPDLVLLDIMMEPMDGWETLERIKT--DPATRDIPVLMLTAKPLEEANEYGSYIEDYILKPTTHHQLYEAIEHVLARRHSIA................................................................................................................... 128
41 -29.8003gt7_A mol:protein length:154 Sensor protein  ali model follow..  27  6.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RAGEILIVEDSPTQAEHLKHILEETGYQTEHVRNGREAVRFLSLTRPDLIISDVLMPEMDGYALCRWLKG--QPDLRTIPVILLTIDPRDVVRSLECGADDFITKPCKDVVLASHVKRLLSGVKRTE................................................................................................................... 132
42 -29.4002zay_A mol:protein length:147 Response regulator receiver protein  ali model follow..  18  7.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KWWRIMLVDTQLPALAASISALSQEGFDIIQCGNAIEAVPVAVKTHPHLIITEANMPKISGMDLFNSLKK--NPQTASIPVIALSGRATEEAQLLDMGFIDFIAKPVNAIRLSARIKRVLK......................................................................................................................... 127
43 -29.4003a0r_B mol:protein length:116 Response regulator  ali model follow..  21  3........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RILVVDDEPNIRELLKEELQEEGYEIDTAENGEEALKKFFSGNYDLVILDIEMPGISGLEVAGEIRKKK----KDAKIILLTAYSHYRSDMSSWAADEYVVKSFNFDELKEKVKKLLS......................................................................................................................... 116
44 -29.3003cg4_A mol:protein length:142 Response regulator receiver domain protein (CheY-like)  ali model follow..  17  9........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DVMIVDDDAHVRIAVKTILSDAGFHIISADSGGQCIDLLKKGFSGVVLLDIMMPGMDGWDTIRAILD--NSLEQGIAIVMLTAKNAPDAKMLQEYVVDYITKPFDNEDLIEKTTFFMGFVRNQT................................................................................................................... 132
45 -29.2002j48_A mol:protein length:119 TWO-COMPONENT SENSOR KINASE  ali model follow..  13  1......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AGHILLLEEEDEAATVVCEMLTAAGFKVIWLVDGSTALDQLDLLQPIVILMAWPPPDQSCLLLLQHLREH--QADPHPPLVLFLGEP-PVDPLLTAQASAILSKPLDPQLLLTTLQGLCPPN....................................................................................................................... 119
46 -28.9006azr_B mol:protein length:123 Chemotaxis regulator-transmits chemoreceptor signals to flagelllar motor components CheY  ali model follow..  29  1....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MMSKKVLLVDDSAVLRKIVSFNLKKEGYEVIEAENGQIALEKLSEFTPDLIVLDIMMPVMDGFTVLKKLQE--KEEWKRIPVIVLTAKGGEEDESLSLGARKVMRKPFSPSQFIEEVKHLLNE........................................................................................................................ 123
47 -28.8004ja2_A mol:protein length:122 Response regulator  ali model follow..  28  2......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SKKVLLVDDSAPIRKMVSFVLKKEGYEVIEAENGQIALEKLSEFTPDLIVLDIMMPVMDGFTVLKKLQE--KEEWKRIPVIVLTAKGGEEDESLSLGARKVMRKPFSPSQFIEEVKHLLNE........................................................................................................................ 122
48 -28.7005idj_A mol:protein length:242 Cell cycle histidine kinase CckA  ali model follow..  25  2...............................................................................................................................................................................................................................................................................................................................SQAQKMQAIGQLAGGVAHDFNNLLTAIQLRLDQLLHRPVGDPSYEGLNEIRQTGVRAADLVRKLLAFSR----KQTVQREVLDLGELISEFEVLLR-RLLREDVKLITDYGRDLPQVRADKSQLETAVMNLAVNA---KGGGVVRIRTAADGDTAFIEVSDDGPGIPPDVMGKIFDPF----TTKPVGGTGLGLATVYGIVKQSDGWIHVHSRPNEGAAFRIFLPVYEA................................................................................................................................................................................................................................................................... 242
49 -28.6004hnq_A mol:protein length:124 Chemotaxis protein CheY  ali model follow..  23  3.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KNMKILIVDDFSTMRRIVKNLLRDLGFNTQEADDGLTALPMLKKGDFDFVVTDWNMPGMQGIDLLKNIRA--DEELKHLPVLMITAEAKREAEAAQAGVNGYIVKPFTAATLKEKLDKIFE......................................................................................................................... 124
50 -28.5001p6q_A mol:protein length:129 CheY2  ali model follow..  20  5.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EKIKVLIVDDQVTSRLLLGDALQQLGFKITAAGDGEQGMKIMAQNPHHLVISDFNMPKMDGLGLLQAVRA--NPATKKAAFIILTAQGDRALKAAALGANNVLAKPFTIEKMKAAIEAVFGA........................................................................................................................ 127
51 -28.4003cnb_A mol:protein length:143 DNA-binding response regulator, merR family  ali model follow..  20  7.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NDFSILIIEDDKEFADMLTQFLENLYAKIKIAYNPFDAGDLLHTVKPDVVMLDLMMVGMDGFSICHRIKS--TPATANIIVIAMTGTDDNVSRIVALGAETCFGKPLNFTLLEKTIKQLVEQKKATSEG................................................................................................................. 137
52 -28.4003t6k_A mol:protein length:136 Response regulator receiver  ali model follow..  23  2....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MKPHTLLIVDDDDTVAEMLELVLRGAGYEVRRAASGEEALQQIYKNLPDALICDVLLPGIDGYTLCKRVRQ--HPLTKTLPILMLTAQGDISAKIFEAGANDYLAKPFEPQELVYRVKNILARTTIETPT................................................................................................................. 131
53 -28.3003hzh_A mol:protein length:157 Chemotaxis response regulator (CheY-3)  ali model follow..  17  1...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MRGSGSIQKTTIAADSSSKPRGINYDTGI------PFNVLIVDDSVFTVKQLTQIFTSEGFNIDTAADGEEAVIKYKNHNIDIVTLDITMPKMDGITCLSNIMEFD----KNARVIMISALGKEQLDCLIKGAKTFIVKPLDRAKVLQRVMSVFVK........................................................................................................................ 151
54 -28.3003tz0_A mol:protein length:418 [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial  ali model follow..  16  131...................................................................................................................................................................................................................................................................................................................RAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAGLRESRKHIEDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARRLCEHKGNAPRVRINGVAARFPFIPMPLDYILPELLKNAMRATMESHVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHHSGGQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREES............................................................................................................................................................................................................................................................... 409
55 -28.3003f7n_A mol:protein length:128 Chemotaxis protein cheY  ali model follow..  28  3.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDDESTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWMMPNMDGLELLKTIRA--DGAMSALPVLMVTALAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 127
56 -28.2003ffw_A mol:protein length:128 Chemotaxis protein cheY  ali model follow..  28  3.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDDQSTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWKMPNMDGLELLKTIRA--DGAMSALPVLMVTAYAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 127
57 -28.2001ab6_A mol:protein length:125 CHEMOTAXIS PROTEIN CHEY  ali model follow..  27  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LKFLVVDDNSTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRA--DGAMSALPVLMTTAEAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 124
58 -28.2001udr_A mol:protein length:129 CHEY PROTEIN  ali model follow..  29  4.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDDFSTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRA--DGAMSALPVLMVTAEADAENALAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 128
59 -28.2001ab5_A mol:protein length:125 CHEY  ali model follow..  29  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LKFLVVDDNSTMRRITRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRA--DGAMSALPVLMVTAEAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 124
60 -28.2001hey_A mol:protein length:128 CHEY  ali model follow..  25  3.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVGNGGTGKSTVRNLLKELGFNVEDAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRA--DGAMSALPVLMVTAEAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 127
61 -28.2002id7_A mol:protein length:128 Chemotaxis protein cheY  ali model follow..  26  3.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDDFSTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISCWNMPNMDGLELLKTIRA--DGAMSALPVLMVIAEAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 127
62 -28.2003ffx_A mol:protein length:128 Chemotaxis protein cheY  ali model follow..  28  3.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDDESTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWRMPNMDGLELLKTIRA--DGAMSALPVLMVTAHAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 127
63 -28.1001ymu_A mol:protein length:130 CHEY  ali model follow..  28  5.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDDFSTGRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRA--DGAMSALPVLMVTAEAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 129
64 -28.1003fft_A mol:protein length:128 Chemotaxis protein cheY  ali model follow..  28  3.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDDESTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRA--DGAMSALPVLMVTARAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 127
65 -28.1003rvj_A mol:protein length:132 Chemotaxis protein CheY  ali model follow..  28  7.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDDFSTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWDMPNMDGLELLKTIRA--DGAMSALPVLMVTAQAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 131
66 -28.1001djm_A mol:protein length:129 CHEMOTAXIS PROTEIN Y  ali model follow..  28  4.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDDFSTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRA--DGAMSALPVLMVTAEAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 128
67 -28.1006chy_A mol:protein length:128 CHEY  ali model follow..  27  3.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDDFSTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRA--DGAMSALPVLMVIAEAKKENAAAQAGASGWVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 127
68 -28.1001u8t_A mol:protein length:128 Chemotaxis protein cheY  ali model follow..  27  3.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDKFSTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRA--DGAMSALPVLMVTAEAKKENAAAQAGASGWVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 127
69 -28.1001ymv_A mol:protein length:129 CHEY  ali model follow..  28  4.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDDGGTGRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRA--DGAMSALPVLMVTAEAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 128
70 -28.1002fka_A mol:protein length:129 Chemotaxis protein cheY  ali model follow..  27  4.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDDFSTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGFGFIISDWNMPNMDGLELLKTIRA--DSAMSALPVLMVTAEAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 128
71 -28.1001e6m_A mol:protein length:128 CHEMOTAXIS PROTEIN CHEY  ali model follow..  27  3.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDDFSTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISAWNMPNMDGLELLKTIRA--DGAMSALPVLMVTAEAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 127
72 -28.0001e6k_A mol:protein length:130 CHEMOTAXIS PROTEIN CHEY  ali model follow..  27  5.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVADFSTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRA--DGAMSALPVLMVTAEAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 129
73 -28.0003to5_A mol:protein length:134 CheY homolog  ali model follow..  22  11.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KNMKILIVDDFSTMRRIVKNLLRDLGFNTQEADDGLTALPMLKKGDFDFVVTDWNMPGMQGIDLLKNIRA--DEELKHLPVLMITAEAKREQEAAQAGVNGYIVKPFTAATLKEKLDKIFER........................................................................................................................ 133
74 -28.0001jbe_A mol:protein length:128 Chemotaxis protein CHEY  ali model follow..  28  3.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KELKFLVVDDFSTMRRIVRNLLKELGFNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRA--NXAMSALPVLMVTAEAKKENAAAQAGASGYVVKPFTAATLEEKLNKIFEKLG...................................................................................................................... 127
75 -27.8003lte_A mol:protein length:132 Response regulator  ali model follow..  22  5.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................QSKRILVVDDDQAMAAAIERVLKRDHWQVEIAHNGFDAGIKLSTFEPAIMTLDLSMPKLDGLDVIRSLRQNKV---ANQPKILVVSGLDKLQQAVTEGADDYLEKPFDNDALLDRIHDLVNEG....................................................................................................................... 126
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I. and Godzik A Connecting the Protein Structure Universe by Using Sparse Recurring Fragments. Structure (Camb.) (2005) Aug;13(8):1213-24