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Query: ACL93470.1, from C.crescentus

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTNAITGAAIVGGVCGQPIKHSMSPVIHNAWIAAAGLDAAYVPFAPAADRFETFVDGLRGGAVRGLNVTIPFKERALAVADTASDLARMAGAANLLVFNEDGSVHADNTDGPGLLGAIAIQAPGFDVTAAPVVILGAGGAARGAVAALLLAGAPRIAVVNRTVARAQDLADTFGEKVVAKGEDALPALLPEAGLIINATSLGLGGGAGPSADLTLTPKTAVVMDMVYKPLRTEFLRRAEAAGRRTVDGLEMLLRQAIPTFETIYGQAPSPKIDVRVLALKLLGEVLast
1 -92.900[E] COG0169 Shikimate 5-dehydrogenase  ali follow..  34  1....MASQIDQYAVFGNPINHSKSPFIHTLFARQTQQSMIYTAQCVPVDGFTEAAKHFFAQGGRGCNVTVPFKEEAYRFADRLTERARLAGAVNTLKKLDDGEILGDNTDGEGLVQDLLAQ--QVLLKGATILLIGAGGAARGVLKPLLDQQPASITVTNRTFAKAEQLAELVAAYGE-VKAQAFEQLKQSYDVIINSTSASLDGEL-PAIDPVIFSSRSVCYDMMYGKGYTVFNQWARQHGCQAIDGLGMLVGQAAESFMLWRGLRPGTKQILRELRKNLEGAL 278
2 -13.000[H] COG0373 Glutamyl-tRNA reductase  ali follow..  17  51......NRTEIYCDVRSASKNKVIEWLSQFHQVSLDELKPSLYVHEEQAAIRHLMR------ACGLDSLVLGEPQILGQVKQAYAEARENHAVNPATEKSVAKRVRTETEIGGSAVSVAYAACTLSLADATVLLVGAGETIELVAKHLAGHHCKRMIVANRTRERALSLAQQFGAD--VIALNEIPDYLAQADIVISSTAS-IGKGMVESALKARRHQPMLLVDIAVPRDIEPQVGKLNDAYLYSVDDLQSIVDSNIEQ.......................... 311
3 -11.400[E] KOG0172 Lysine-ketoglutarate reductase/saccharopine dehydrogenase  ali follow..  17  393.......................................................SGILMCSIDNLPAQLPFGDMLYPYVEEMILSQNFSPVVRDAVITSNGTLPDKYKYIQTLRESRERAQSLSMGTRRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMQEEKLGFLVAKQDLVISLLPYVLH----PLVAKACITNKVNMVTASYTPALKELEKSVEDAGITIIGGLDHMLAM-IESYISYCGGLPAPEHSNNPLRYKF.... 650
4 -11.000[E] COG1748 Saccharopine dehydrogenase and related proteins  ali follow..  21  2................................................................................................................................KKNVLIIGAGGVAQVVAHKCAQNSLGDIHIASRTVDKCRKIVESVREKLDALDVEATKALIVSSQIVINVGS----AFVNMSVLRACMDTGVAYMDT-YGNYEWKRAAECKEKGITAILGVGAYARLAKDEYF........................ 168
5 -10.200[R] COG5322 Predicted dehydrogenase  ali follow..  13  1MNPSTAPKTMKFGFIAHPTSVALKRHVKIVDLLE--RDDRWQWRNLVPFADFGRIVSAQGAVCEGILHYMPL-VDAVESLKDQGAQVVGLGGFTAIVGNRGLQTTGNSLTAYAAYRNVLEDRLGVEPADTEVAVVGYPGSIALVIAKLLAGHGCRLCLVHRGSEAQGRQGLAYPMHAQVRLSNDIEHCYEHVQFYVAATS------TGGLIDPYRLRPGSVVVDAAL-PRDVK--YRKDRNDILIIDG..................................... 277
6 -9.600[E] COG0703 Shikimate kinase  ali follow..  4  1......................................................................................................................................................................................................................MVARQRACSDQICRGMGD-LFSCQTRWSIEIIFSLTLAISYEVSVHVLRSSLSEAGLSLTNSLSS...... 64
7 -9.480[E] KOG3007 Mu-crystallin  ali follow..  14  57...........................................LLIMPCWIPGKFLGVKQVNVFPENTKLPSLSSHYLLSDATTGCHLAQLDGNELTSRRTAAASALASSYLS------------KEDSTSLLIIGSGKVAEKLIHAHCSRPIRSVRIWNHRFESAKSLASRASKEIDAVPIQNLENAVKCSDIISSATLVGGFTPHMHEADSKCIQISNVFVD............................................................. 252
8 -8.790[Q] COG5310 Homospermidine synthase  ali follow..  16  17................................................................................................................................TGPVVMIGFGSIGRGTLPLIERHFKSRMTVLDPRDTDRKLLDEAVTENNYKKLLTPLLTNGGGQGFCVNLSV----DTGSVDLMRLCRKLGVLYIDTVVEPEAMIKEKHDKPGGATVVSTCGWFVKQALVNLA........................ 184
9 -8.650[R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity  ali follow..  14  4.............................................................................................................................SLQGKIAVITGAAGIGLATTEALLEQGA-TVVMVDWNEKALNDLAAKLGERAIPQVTNEILGKVDHIDILYCNAGTYIGGDLTETTPEAIDKMLNLNVNAVMKNVQAVVPHMSERKTGDIIVTCSIAGHFPTYWEPVYSGSKWAITSFVQGMRRQMIPH. 174
10 -8.570[Q] COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis  ali follow..  17  10..................................................................................................................................RVLIVGAKGEMYLNAFMQPPEGLELVGLLAQGSARSRELAHAFGIPL----YTSPEQITRMPDIACIVVRSTVAGGTGTQLARHFLTRGVHV--IQEHPLHPSLQTLAQEQGCCYWVNTFYPHTRAGRTW......................... 138
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.