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Query: ACL93471.1, from C.crescentus

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLILGLTGSIGMGKSTTSKMFQDEGVPVYDADAAVHALYASGGAAVAPVETAFPGVVVDGAIDRAKLSAQVVGNSEALAKLEAIVHPLVGAHRIGFFEQAKAEGHEIVVLDIPLLFETGGEKRVDKVVVVSAPAEVQRERVLARPEMTPEKFEAILARQTPDADKRARADFVIDTGQGLDHARRQVRDLLTLLRTARSALast
1 -88.300[H] COG0237 Dephospho-CoA kinase  ali follow..  38  2TLVIGLTGGIASGKSTVANMLIEKGITVIDADIIAKQAVEKGMPAYRQIIDEFGEDILNGDIDRKKLGALVFTNEQKRLALNAIVHPAVRQEMLNRRDEAVANREAFVVLDIPLLFESKLESLVDKIIVVSVTKELQLERLMKRNQLTEEEAVSRIRSQMPLEEKTARADQVIDNSGTLEETKRQLDEIMNSW...... 196
2 -80.000[H] KOG3220 Similar to bacterial dephospho-CoA kinase  ali follow..  31  1MFIVAVTGGIATGKSTISKVFERQGIPVIDADKIAREIVEPGQPCWRQIREVFGDEVLSKEINRAVLGKMIFEDKELRGKLNKITHPTIHRKIFWQVCKLLVTGHAWIVLDLPLLFETGLMDFIHKIVCVTCDSDKQLERLIARNELSESEARHRVDSQMPLDKKCEKSHFVIDNNGSVEEAESSAMSIYNLMRDSKQ. 201
3 -17.800[F] COG0572 Uridine kinase  ali follow..  15  9.VIIGIAGASASGKSLIASTLYREHIGVIPEDGYYKDQSHLSMEERVKTNYDHPSAM-DHNLLLEHLQALKAGKPVELPLYSYTEH-------TRKKETVHLEPKKVIILEILLLTDIRLRQEMNFSIFVDTPLDICLMRRMKRDVNERGRSMDSVMAQYQKTVRKQYADIIVPRGGKNRIAIDILKAKISQFFE.... 213
4 -17.300[FH] KOG2702 Predicted panthothenate kinase/uridine kinase-related protein  ali follow..  17  128.RLVGLAGPPGAGKSTVANEVVRR-AIVLPMD------FHLYRSQLDAMEDPKEAHARRGTFDPALLLNCL----KKLKNEGSVYVPSFDHGVGDPVEDDIFLQHKVVIVE--ILLEEGISDMFDEKWFIDVNLDTAMQRVENRHGKPPDVAKWRVDYN--IIKSKTNADLLIRSM....................... 331
5 -16.900[F] COG1102 Cytidylate kinase  ali follow..  16  5CLVITVSGLAGSGTTTLCRNLAKYGFKHVYAGLIFRQMAKERGMSLEEFQKY----------------------AELHPEIDREVDRRQVEAAKECNVVIEGRLAGWMVKNADL-------------IWLDAPIRVRAERVAKREGISVEEAFMKIAEREMQNRKRSIYDLIIDTSKSPEGVFAIVKAAIDHLYEK... 180
6 -16.100[H] COG1072 Panthothenate kinase  ali follow..  16  81.YIISIAGSVAVGKSTTARVLQAL-VELITTDGF-QVLKERGLMKKKGFPESYDMHRLVKFVSDLKSGV------------PNVTAPVYSHLIYDVIPDGDKVQPDILILEGLNVLQSGVSDFVDFSIYVDAPEDLLQTWYINRAKLTKEEAIKTAMTLWKEINWRERASLILTKSANHAVEEVRLRK........... 308
7 -16.000[F] KOG3308 Uncharacterized protein of the uridine kinase family  ali follow..  12  5TIIVGVSGASCSGKSTLCQLLHAIGSSLVHEDDFYKEIPVKNGIADWDCQESLNLDAFLENLHYIRDHGVLLRNRENKNVAPEALIEYADIIKEFKAPAIPTLEQHLVFVDGFMMYNEDLINAFDIRLMLVTDFDTLKRRREARTGYITLE................................................ 164
8 -15.800[F] KOG3347 Predicted nucleotide kinase/nuclear protein involved oxidative stress response  ali follow..  15  3LPNILLTGTPGVGKTTLGKELASSGLKYINVGDLARE---------EQLYDGYDEEYDCPILDEDRV-----------------------------VDELDNQMREGGVIVDYHGCDFFPERWFHIVFVLRTDTNVLYERLETRGKLTDNIQCEIFQVLYEEATASYKEEIVHQPSNKPEELENNVDQILKWIEQ.... 165
9 -15.700[V] COG3896 Chloramphenicol 3-O-phosphotransferase  ali follow..  16  25..LILLNGGSSAGKTSLALAFQDL----IGIDLFWFALPPEQLDLARVRPEYYT----DSAVEADGLEWFTVHPGPILDLAMHSRYRAIRAYLDNGMN---------VIADDVIWTREWLVDALRVFVGVHVSDEEGARRELERG----DRHPGWNRGSARAAHADAEYDFELDTTAPVHELARELHESYQA....... 209
10 -15.200[C] COG3954 Phosphoribulokinase  ali follow..  14  6.PVIAVTGSSGAGTTTTSLAFRKIHAAEVEGDSFHRYTRPEMDMAIRKARDAGRHEANDFSLLEHTFIEYGQTGKGQSRKYLHTYDEAVPWNQVP--WQPLPEPTDVLFYE-----QHDVARHVDLLVGVVPIVNLEWIQKLIRDGHSREAVMDSVVRSMDDYINFSRTHINFQRVPTVDTSNPFAAKGIPSLDES... 228
11 -14.700[R] COG0645 Predicted kinase  ali follow..  15  2.FLAVTHGVSAVGKSQVAMRLVELGAVRLRSDIERKRLFG-----------------EQPEHDRGQFAAGIYSSQASEATYAHLHQ----------LAAKILQAGYPVVIDAAYLKQNQRQAACHLILDCQAPEAVIAGWLAQRQAATLDVIRTQQATREPLTAAETVQSKRVDTHDALDGLVDGIRQRLPGL...... 185
12 -14.200[F] COG1936 Predicted nucleotide kinase (related to CMP and AMP kinases)  ali follow..  15  1.MLIAITGTPGVGKTTVAKLLAKLNYEYVSLKDFALE-----KGCGRRVNDEVEVEI---------------------------------DELAYFIERELKGKNAVLDGHLSHLMPV------DLVVVLRAHPKLIGERLRERGKIGENVEAELVDAVLIEAIEEHENVIEVDTNKSPEDVVEEIVSLINSGIKKRVG 160
13 -14.200[TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin  ali follow..  11  65LILVGLAGPSGAGKTIFTEKILNFSIAIINMDNYNDGTRVIDGN----------PRLTDYDTLLDNIHGLRDGKPVQVPIYDFKSSSRIGY------RTLEVPSSRIVILEGIYALSEKLRPLLDLRVSVTGGVHFDLVKRVLRDIQRAGQEPEEIIHQISETVYLKTAQIKILNKFNPFSGFQNPTYILKSSKAVTP. 261
14 -14.100[P] COG3709 Uncharacterized component of phosphonate metabolism  ali follow..  15  16.TMIVIVGPSGAGKDTLMDYAAAQ---HFTRRVITRSCDAGGENHDAVSMHEFNQLEDAGAF-----------------AVSWQAHGLKYGIPAAVYRHLEAGDVVIANGSRSALPHFGTAFSRLKVVNIVARPDVLARRLEQRGRESRDDILRRLE-RSSLAVAGDFDVTTVDNSGAIEDAGKTIMQVLQQSAGSSQ. 198
15 -13.800[F] COG2019 Archaeal adenylate kinase  ali follow..  12  1.MRSVITGVAGVGKTTVLDIVARSGIPVVNYGTLMFEVAKRRG---------------------------LVENRDQIRKLSRETQVDLQKLAGEEIGKMEN-----AIVDPGLPEWVLRSINASVFVIIEADPAIIKRRRDNRDDEGVDSIREHQEMNRYFAAAYSIF-IVKNEEGKPEQAADEIVRVIK........ 181
16 -12.400[F] COG4088 Predicted nucleotide kinase  ali follow..  12  1MPLIIVSGYPSSGKTTRSN----------------------------ELKKALEDRIHQNIDNTKDYRVIIINDESLNIEKETYRESKNEKAARGLLYSAVQRKSTFVICDALNYIKGFRYQLYCEVIHVAVPQDLCRKFNSNKEQPYPDDVLEQLMFRYEEPNGMTRWDFTVLHDDASCPIDDIWSVLIHN....... 179
17 -12.300[G] KOG3354 Gluconate kinase  ali follow..  13  17FVVIGPAG---SGKTTMAKAVSELGFEYIEGDD------------------------LHPKANIEKMSQHPLNDNDRWGWLHNC--------GGACAMELDKESIKGVVLTCSALKRSYRDILRSSLIYLAASRETLIKRTTSRKN------ADMVESQLAILEAPTADEITISVENGKEQSEEECLDIVHKMVNENK. 191
18 -12.100[F] COG1428 Deoxynucleoside kinases  ali follow..  11  7.KVIVLAGMIGAGKSSYTELI---------ANELGTKAFYESIKDNRILEMFYDDPKRWAALQIYFLNTRFRSIKAALTDQNNVLDRSIYEDAEGNISEPEMDTYLDLLDNMMEELAYMPKKAPDLLIYLRGSLDTVLSRISLRGRPYEQTFDNPGLLDYYKHLHSRYDSWVINIDEVDINKPSDAKYVMQLIHE.... 210
19 -11.800[R] COG3911 Predicted ATPase  ali follow..  16  9...FVLTGGPGSGKTTLIAALRRAGFATS--VVAGRGIVRDQSSIGGTALPLFAELMLSWEMRSYQ-KGPVFFDRGVPETL-RLSGLPVADHVSTAAKRFRYNPRVFIAPPWPDIFAQDEERKYELVPLPLAPVETRLRFVLADAGLN................................................... 183
20 -11.700[S] COG4185 Uncharacterized protein conserved in bacteria  ali follow..  18  14..FLIVAGPNGSGKSSVYANADLESVWIVNPDLLAGRISEVENKP-LPEANLVAVQRIEAWIQSSISVHKTIGVETVLSTDKYR----------RLVEAAEAVGFAIWL-----------------FYTVLDSPERSIERIKLRHDVPADKVRARYARSLDQPWFLERADWIWDNSGATPKLIGEKQD........... 183
21 -11.500[G] COG2074 2-phosphoglycerate kinase  ali follow..  10  92.LIILIGGASGVGTSSIAFEVNRLGIRNMISTDMIREVMRKIVSR-ELLPSIYESSYTAYQSLRIPPPPELDEVLIGFRDHVESVSIGVEAVIERALTEGIS-----IVIEGVHIVPGFIREDLVNFVLTVSDENVHKGRFYSRCRQMWAR-AIRRIHRYIENQARKHGVPVIENIDVVTTIDSIIKSLTKTTVKGGEK 300
22 -11.500[G] COG3265 Gluconate kinase  ali follow..  13  6IIVMGVSG---TGKSCVGQALALLGAKFIDGD-----------------------DLHPRANIQKMAAGQPLNDQDRAPWLERLSDVAYSLQQKNEVGFLVCSALKKQYRDRLREGNEGI-----RFLWLTGDYDLVLHRMQQRAG------ESLLKSQFATLEAPGSDEIPIDISSSIADVVEHCIAALSLENHVSAI 175
23 -11.400[R] COG4240 Predicted kinase  ali follow..  11  89.FIQGILGSQGTGKTTMSLVIQLIRTLSLSLDDL---KTYSDRLVLLQQDPRLIWRGPPGTHDIDLGLNVL---EQIRQGKSPVIVPRFDKSAHAGAGDRTITGVDILIFE--VGVRPIDPSLFNPPSPILTDEDKAFARDMNLRLNHYLPLWEKLDSLILLYPTRKQAEQKMIAAGKTGMSNTQIEEFVNYFWRS... 298
24 -11.200[C] KOG3877 NADH:ubiquinone oxidoreductase, NDUFA10/42kDa subunit  ali follow..  12  83.KVICVEGPIAAGKSKFAKELAELDMEYYPAVDLDLIYINSYGYDMRKLDPQLPPSCRSYDVRN------FCLDPSHDLAAQQIRMYMLRYSQYIDALQHVLSTGQGVVLESDFVFMEAMFRQ-HLVIYLDLPVDAVKKQIKARNVDYEVQSKVFSDAYLSDSTHAELLIYDWTAGGETEVVVEDIERI.......... 307
25 -11.100[F] KOG3079 Uridylate kinase/adenylate kinase  ali follow..  14  36.LVVFVLGGPGAGKGTQCARIEKYGYTHLSAGELLRDERKNPDSQYGELIEKYEGKIVPVEITISLLKREMDQTMAANAQKNKFLFPRNQDNLQGWNKTMDGKAD------------------VSFVLFFDCNNEICIERCLERGKSSSDDNRESLEKRIQTYLQSTKP-KKIDASKSVDEVFDEVVQIFDK....... 226
26 -11.100[F] COG0125 Thymidylate kinase  ali follow..  12  4.LFITFEGPEGAGKTTVLQEIKNI------LTAEGLQVMATREPGGIDIAEQIREVILNENNILDPKTEALLYAAARRQHLVEKVKPALEQRFIDSPLAYQGYARGLGIDEVLSINEFAIGDMMHVTVYFSIDPEEGLKRIYANGSREKNRLDKVQEGYQELMKRFPERFHSVDAGQSKDLVVQDVLKVIDEALKKIQ. 211
27 -10.900[R] COG0523 Putative GTPases (G3E family)  ali follow..  16  9.....LTGFLGAGKTTLLRHI----------------LNEQHGFKIAVIENEFGEVSVDDQL-------IGDRATQIKTLTNGCICCTRSNELEDALLDLLDSRDRGDIAFDRLVIECTGMADPGPIIQTFFSHDVLCERYLLDGVIALVDAVEQMNQFTIAQSQIGYADRILLTKTDVAGDSEKLRERLARINARAP. 181
28 -10.200[E] COG0703 Shikimate kinase  ali follow..  18  74...IFLVGPMGAGKSTIGRQLAQLNMEFYDSD---QEIEKRTGADVGWVFDLEGE-------------------------------EGFRDREEKVINELTEKQGIVLATGGGSVKSRETRNRLSAVVYLETTIEKQLARLLHVETPPREVLEALANERNPLYEEI--ADVTIRTDD--QSAKVVANQIIHMLES.... 239
29 -9.950[F] COG0283 Cytidylate kinase  ali follow..  14  5.KVIAIDGPGASGKGTVAARVAALGYDYLDTGALYRLTA-HDEENVSELAKKLPAVFSDSRLGGEDVSDGIRTEAIGMGASAVAQLPKVRASLLQRQRDFLTEKG--LVAD----TGSVVFPQAELKIFLTAESKIRAERRAKQEGLAFERILSDIEARDEADRNRKVAPLLLDTSRTIEETVKKVLDWYRKV...... 218
30 -9.850[R] KOG3062 RNA polymerase II elongator associated protein  ali follow..  14  1MPLVVITGLPASGKSTRARQLRDHKVHLISENEAVPKAGFGKNSH--------------------------TGDSQKEKVVRSDLKSEASRHLNQ---------EDLVILDAGNYIKGYRYELYCMTVFTCIPQEEAWTFNSQRDTLDMEAIYKALYESQPLPPNQSTYNAPLGTTNYLFELDKIVQAIIKEILGAVKI 233
31 -9.790[F] KOG0707 Guanylate kinase  ali follow..  16  139..PIVISGPSGVGKGTLISMLMKFGFSVSHTTRSPRSMEMDGVHYHFADKKVMEKEIKDGKLEFASVHGNLYGTS--IESVEAVT-----------------DSGKRCILDIDV-ARSVRASSLDAIFIFVCPPSMKEDRLRARGTETEEQIQKRLRNEIKEGISSGIFGLILYND-NLEECYKKLKVNHLLLIAQ... 324
32 -9.760[F] COG0194 Guanylate kinase  ali follow..  12  46.LLIVLSGPSGVGKGTVRQAITKFEYSISVTTRSPREGEVNGVDYFFKTRDEFEQMIADNKLEWAEYVGNYYGTP--VDYVEQTL-----------------QDGKDVFLEIEVQGALQVRNAFPEGLFIFLSLSELKNRIVTRGTETDALIENRMKAAKAEIEMMDAYDYVVEND-NVETACDKIKAIVLA....... 225
33 -9.690[H] COG3172 Predicted ATPase/kinase involved in NAD metabolism  ali follow..  11  8VRTVAILGGESSGKSTLVN----------------------------KLANIFNTTSAW-EYGRDYVFSHLGGDEIALQYSDYD---KIALGHAQYIDFAVKYANKVAFIDTDFV-ALIDEYRFDLVILLENNTPWVADGLRSLGSSVDRK---EFQNLLVEMLEENNIEFVRVEEEDYDSRFLRCVELVREMMGEQR. 187
34 -9.610[R] KOG2878 Predicted kinase  ali follow..  16  26.FILGISGPQGSGKSTLASALDTESVVKFSLDDFEQVELAKNNPNNPLVQHRGLAGTHDVTFLNNVLNAFVKGSD------EEVSIPFYDKSKFGGYGDRGDESQWKKANPKTVIFEVGFEPLDSCMLSVRARSTRWQNIEGSLLWVNRQKIDSLVELEAQEINYRLQQEHALKARIHKGMSDEEVIEFVNHYMPQYV. 246
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.