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Query: ACL93486.1, from C.crescentus

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTQRDTGRLDAIVLAAGRGVRFGGGKLTALLDGDPLVAAALLTAFLAPARRVVVAVGPEPDVRQAVEATATRLLARERLVLVPIDDPSAGMGASLAAAARSLPGDTDGVFVFLGDMPRIDPATPRHLAAALRDPGDIVAPTYLGRRGHPVLFGARWAPVLGALSGDEGARAIVDKAGESLVLVPVDDPGVHLDVDRPSDLARVQTDRRTLLast
1 -74.800[R] COG2068 Uncharacterized MobA-related protein  ali follow..  31  3LPAKSRLKVGIVLLAAGRSSRMGGNKLLALFDGKPLVRRTAERALGSKASGTIVVTGHQRERVRAA-------LSGLDVTFADNPDFANGLSTSLKAGIAYLPEDTAGAMIVLGDMPGVVSGDLDRLIDAFRKGNSVVRASHQGKRGNPVLLPRALFPAIAHLEGDTGARHLVEAEGLDVVDVEIGE-GASVDVDTREALEGAGGVLQD. 206
2 -35.300[H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A  ali follow..  18  2.......KHVNVLLAGGASRRFGEPKAFVKWKGRMLYECAKEALG----EQTVIISRPEF-------IDRFQENGENEVYQDAEPFQGMGPLAGIYTAFKKTDGDL--YTVLSCDTPLIQRRTMLELKRLMIAGADAVVPISDGQV-QPLIYHKRIMPVLYDQEKRLRISDLLGRISVCYVQAE-ANPAEFININTRDDFSCLEEKSNS. 195
3 -33.800[H] COG2266 GTP:adenosylcobinamide-phosphate guanylyltransferase  ali follow..  15  1........MLTLLMCGGKGTRLGREKPLFEVCGMKLIDHSLLQYKDF---DVIAITSPHTPATE-------SYLAEKGVEVYRAAG--KGYIEDYSEACRELAIN-EPVIVASADIVYIRDIAFDIVDAYMKTIKPALTVVMEGEPVGVNIIDSLLINTWQE------------------EEIYSIEKDSVVNVNTVADVERAERLWTT. 171
4 -22.400[M] COG1213 Predicted sugar nucleotidyltransferases  ali follow..  18  1........MEAVILAAGFGSRLGHPKALLKIGKRPLIYYTVQTLMENGIRDVVVVTGHKGYVLREYLSQ-----FDLNFKFVHNSLYKKNNIYSLYLAMDHVSKG---FYILNSDV-LFHPGIFRELHSSTKENLILSVDTFKELGEEEMKVEENIIDDLYNHVSRVMERKGRRVFYEEAFQSMMDDGIAVIEIDTPADLMKARYE.... 234
5 -20.800[I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase  ali follow..  20  5.IAKSTRRIVAVVPAAGIGSRMQMPKQYLHIHGKTILEHTLSVLLGYPIEKIILAVAANDPYISTCP-----LLTHPKIQLVEGGSSRA---DSVLNGLNAVKSAVQN-WVMVHDRPCLTHQDLDKLVQVEDQNGAILAIPATDT--TPQFFPIATLAQALEQALAQGLQSAMEFAGFRPHLVAGRSDNI--KVTRPEDFA......... 228
6 -20.600[M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)  ali follow..  19  2....PQNTLNIVILAAGKGTRMYSPKVLHEIGGETMLGRVIDTAAALNPQNICVVVGHGKEQVLDTVKRDVVWVEQTE---------QLGTGHAVKTALPHLAAE-GRTLVLYGDVPLIDVETLETLLEAAGNEVGLLTDVPADPSGLGRIINAKLEAWLNSLSSNNAQGEKAVADGIKIHPVQVRSSHLAAGVNNKLQLAELERIFQT. 240
7 -20.100[S] COG1920 Uncharacterized conserved protein  ali follow..  14  1........MKTCAIIPVSRFTHAKTRLSPTLSPKAMLMDVSGALARHVDRVLVISADEDVLEYAYSLGLK-----------ILEEEGERDLNGALEQAMDFCAPEFDRVIITPSDIPLIGKADVSNLLDHASRADVVIAPANGG--GTNTLILRPSAMSLR-FGDCSFFEHIHEARERGLSVSVYDSFYLSLDVNTAEDLGEIILH.... 191
8 -20.000[M] COG4750 CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes  ali follow..  16  1........MKAIILAAGLGTRLNTPKALVQVNQKPLIEYQIEFLKEKGINDIIIIVGYLKEQFD-------YLKEKYGVRLVFNDKYADNNFYSLYLVKEELANS----YVIDADNYLFKNMFRNDLTRSYGDDYKVQDIIVDSKAGR-SFWDAPTAEKIVSIDKAYVSGEFVDLYWDNMVKDNIKELDVYYEIDSVQDYRKLEEILKN. 227
9 -19.800[M] COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase  ali follow..  20  2......TNFTVIIPARYASTRLPG-KPLAEIAGKPMIAHVFEKAMQSGAKRVIVATDHEQ---------VATVARGFGAEVCMTSETHQSGTERLAEVVEKLGIAEDEIIVNIGDEPLIPPAIVRQVAENLAKYQVKMASLAVDHAGYVLYFSRAPIPQPSVLEQIESLEQLRVLWYGEKIHVELAREVPPVGVDTAEDLEKVRSILEK. 258
10 -18.700[M] COG1861 Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog  ali follow..  12  2......NDILFIIQARMGSTRLPG-KVLRPLGSNRLLDILVHRVRQSARDNLVIATSDKET-----DDILEAHCIKQGFRVF------RGSEERVLDRFVKVIEKPSVIIRLTGDNPFVDPELLDVMIQAHFDQGSDYTYILNAPLGICGVVNANLLIDISRIQALEHVTLYIRNHPALYRVQFLE-PQYRLTIDTKEDYESIKALYQKA 212
11 -16.500[M] COG1083 CMP-N-acetylneuraminic acid synthetase  ali follow..  13  1..MKIIMTRIAIIPARAGSKGI-KDKNLQLVGGVSLVGRAILAAQESGMFDQIVVTSDGENILKEATKYGAKPVARPE----SLAQSDTRTIDAILHCLETLNISQGTAALLQPTSPLRNALDIRNAMEIFLGGKYKSVVSACECEHHPYKSFESPRQKLPKSYRANGAIYINDIFIAPMRFYLMPTYRSI-DIDSTLDLQLAESLISK. 226
12 -16.300[M] COG1210 UDP-glucose pyrophosphorylase  ali follow..  13  8..........AVIPAAGLGTRFAQPKEMLPIVDKPAIQYIVEEAAESGIEDILIITGRNKRSIEETLKEMQQIADLANIHYIRQKE-PLGLGHAVLCAEHFIGD--EPFAVLLGDD---ETPALRQLMDVYDVYGTEVVGVQSVLPEDVYVLNSSIFSVLKTIGNEIQLTDALREVCRKEPIHARLLEGNRYDIGDKLGCFKA....... 265
13 -15.400[M] COG1209 dTDP-glucose pyrophosphorylase  ali follow..  17  4........RKGIILAGGSGTRLAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQTPRFQQLLGDGSQW--GLNLQYKVQPS-PDGLAQAFIIGEEFIGG--DDCALVLGDN-IFYGHDLPKLMEAAVNKESGAT-VFAYHVNDPERYG------VVEFDKNGTAISLEEKPLE................................ 166
14 -14.300[MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)  ali follow..  15  1........MRAVLMAGGSGTRLDLPKPMVPILNRPIAEHIINLLKRHHITEVIATLHYLPDVLRDYFQDGGDF--GVQMTYAVEEDQPLGTAGCVKNIAELLD---ETFLVISGDS--ITDFDLGEAIAFHKQKQSKATLILT-RVPNPIEFG------VVITDEAGKIKRFLEKPSTSEIFSDTVNTGTYI.................. 175
15 -14.300[S] COG3222 Uncharacterized protein conserved in bacteria  ali follow..  14  2....SCLPVSVLVVAKAPEPGRVKTRLAAAIGDAAALLDTLDAVAAAPVTARAVALTGDLDS-----AADSAEIRRRLKSFTVFRQRGDAFADRLANAHVDAADGYPVLQI--MDTPQVTAELLADCARLLLQIPAVLGLAFDG--GWWVLGIRTPTAAECLRAVPMSQPDTGELTLKALRDIDVTLVQRLGDFDIVDDIALVRDCCAP. 207
16 -12.600[J] KOG1461 Translation initiation factor 2B, epsilon subunit (eIF-2Bepsilon/GCD6)  ali follow..  14  18.EQSRRQRLQAILLADSFATKLERPNVLLPLVNIPMIDYTLAWLESAGIEEVFVFCSMQVIDYLNNSDWYSHK--DFTVKTIESPQNSTSAGDALRYIYEQQIETSGDFVLVNGCI--VSNMPLTQLIQEHRDRKKMVIRQSLITDHQLFIAVNPLTKQLLYYDEDN-DKSLLDRNPSVLLCSDMQDCYIDI.................. 222
17 -12.400[GMO] KOG1460 GDP-mannose pyrophosphorylase  ali follow..  12  1MGSSMEEKVVAVIMVGGKGTRFNIPKPLFPIAGQPMVHHPISACKRIPLAQIYLVGFYEEREFALYVSAISNEL-KVPVRYLR-EDKPHGSAGGLYHFRNLIMEDSPSHIFLLNCDVCCSFPLPKMLEAHRGYGGIGTLLVIKVSPESASQFG------ELVADPVTNELLHYTEKPETFVSDRINCGVYVFTPEIFNAIGD........ 202
18 -11.200[J] KOG1462 Translation initiation factor 2B, gamma subunit (eIF-2Bgamma/GCD1)  ali follow..  16  32.LQSIPIEFQAVVFA-GFGNSLALPKALLPIGNKPMLHYPLYWLEAAGFTSAILICMEEAEAINAWLRSGYEGHMRIHVEAPTILDDSKSSADALRAVSHLIKSQQNDFVCLSCDS--IVGLPPIYGLDKFRLDNPSALAVY.................................................................... 184
19 -10.700[M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate guanylyltransferase  ali follow..  11  77TQNADPKNVASIILGGGAGTRLFRAKPAVPIGGCRLIDIPMSNCINSGIRKIFILTQFNSFSLNRHLSRTYNVLAATQTSGDAGKKWFQGTADAVRQFIWVFEKNVEHVLILSGDH--LYRMDYMNFVQKHIESNALLKIDQSGK--KPYVFRKEVLLKLLRSSYPTSGSEIIPLAVGEHNVQAFLFNDYWEDIGTIGSFFD........ 357
20 -9.910[G] COG0448 ADP-glucose pyrophosphorylase  ali follow..  13  15.KYELVKDTLVLILAGGRGSRLYRAKPALYFGGNRIIDFALSNCLNSGLNRIGVVTQYAAHSLLRHLQNGWSFLPAERGEFIDDSTWYRGTADAVYQNMAIIRDHYCPKYILILAGDHIYKQDYSQMLLDHHSGAKCTVGCIEVEREKATEFG------VMAVNENLKVKSFVEK................................... 198
21 -9.400[R] COG1216 Predicted glycosyltransferases  ali follow..  14  2....SNKRIGVVIVS---------------YGHEQDVANLVDTFADQLKTGDRVVVVDNRKPWVLKDAVGERL--EKHGAEIINHD-NGGFAAGCNVGAAHIVDDVDLLFFLNPDT-VIDDPTLFNSLRRVDEQWAAFMPYL-NSAGNALHIPVEGSSEVTDISIASGACLAVRV--DWWKRLGGMEELYFMDTD............... 192
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.