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Query: [I] COG0170 Dolichol kinase, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFHPRAACFYLFPLPQNSMKTLLLCGAPLDIVDFMVGTVALEAHGKSFGALERYVVMAILKHIERKLWIGSPLLGVKYTITTGAYKPLLTKISECLAIVDIPGYILHVLDEIRQAPYAFVEIGCILLACLLAQVLLLRSPCTNLKRKTFHLFAFLVFYKEHRVSFLLAEGLLLFMSLLSSCRYTNSLLRPFFSRNDKGRTLLSPIYLLSACMYPRLFIEDVEYVSALISICFQDSAASIAGKWFGVTEKSIQGAIAGVISGTVVYFALYGRIDMLPFFIFAGSVEYLVPINDNITIPLFAVLYFQAPEKACFSSIPSLast
1 -88.400[I] COG0170 Dolichol kinase  ali  100  1MFHPRAACFYLFPLPQNSMKTLLLCGAPLDIVDFMVGTVALEAHGKSFGALERYVVMAILKHIERKLWIGSPLLGVKYTITTGAYKPLLTKISECLAIVDIPGYILHVLDEIRQAPYAFVEIGCILLACLLAQVLLLRSPCTNLKRKTFHLFAFLVFYKEHRVSFLLAEGLLLFMSLLSSCRYTNSLLRPFFSRNDKGRTLLSPIYLLSACMYPRLFIEDVEYVSALISICFQDSAASIAGKWFGVTEKSIQGAIAGVISGTVVYFALYGRIDMLPFFIFAGSVEYLVPINDNITIPLFAVLYFQAPEKACFSSIPS 317
2 -51.800[S] KOG4453 Predicted ER membrane protein  ali follow..  20  80....................................................................................................................FGVTSIVAFSCLGFWGEIGKRGIFDQKLIRKLVHINIGLVFMLCWPLFSSGIQGALFASLVPGLNIVREGTIKSMSRHGDRRELLKGPLYYVLSITSACIYYSSPIAIAVICNLCAGDGMADIVGRRFGTEKKSFAGSIGMATAGFLASVAYMYYFAFLVISIASALVESLPDIDDNLTISLTSALAGFLL.......... 306
3 -47.200[I] KOG2468 Dolichol kinase  ali follow..  21  329.......................................................................................................VLTFVFSEPLKRLSLCIYWILLIVVSVSRFISRSSKVERILLRKYYHLMAVLMFLPALVLAFGAALAVFVALEIIPLGEPLHQFMNAFTDHRDSEHLIVSHFSLLLGCALPIWMSRALSPFAGILSLGIGDTMASMVGHKYGVLRKTVEGTAAGITSMMAVCFVLQGWWSLLVAVTATGMLEAYTAQLDNAFIPLVFYSLLCL........... 598
4 -12.100[I] COG0575 CDP-diglyceride synthetase  ali follow..  16  24..................................................................................................................FAWFMLALAVVTLLGFWEWTQFVNQPSRMLAMIPALLVGGISVALIDFAHFIVLGIGSLWWLVSSGLAITYPRSRPLWEHSSTVRHLFGLFTLLPFFWSVLFLYGAKLVLFVCFLVWAADSGAYFVGKSLGKHKKTIEGLVGGIVTAMLVGYWVSSMPVMLLIILLTVVISVLGDLVESMIIPTAAFPVFALLYFLF...... 280
5 -11.500[R] COG4589 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase  ali follow..  12  63..................................................................................................................KWLALTFFGFISFLSLKEYLTLAPTRRSDSVPLLWMYAAIPLQYVWIGMSWYGMFIIFIPIYVFLFLPARMVLVGDTKGFHSASIMHWGMMATVFALSHVAYLAGALLVIFLVVATELNDISQYLWGKSLGKIKKTLAGLLGGVLTTMLLAAIFGPLLTIGLSGFCGDVVMSAIKRDDSLIYPLFFHFYHYFY.......... 308
6 -9.950[I] KOG1440 CDP-diacylglycerol synthase  ali follow..  20  210...............................................................................................................................................................................................................................LLPASLIIINDIFAYIFGFFFGRTKKTWEGFIGASVTTIISAFVLANILHALCLGLFASIIAPFGGFFASGSIPMVMAVFAYIYLQSF...... 377
7 -9.500[T] KOG2290 Rhomboid family proteins  ali follow..  13  662...............................................................................................................................................LHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLPYRAEVGPAGSQFGILACLFVELFQSFKLLAVVLFLFTFGDNFAHISGFISGKFDLYRKRCQIIIFQVVFLGLLAGLVVLFYVYPVRCEWCEFLT------CIPFTDKFC.............. 845
8 -8.620[P] KOG3684 Ca2+-activated K+ channel proteins (intermediate/small conductance classes)  ali follow..  11  289IFGMFGIVVMVIETELSKDSMFSLALKCLISLSTIILLGLIIAYHTREAQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLIS---------------ITFLSIGYGDMVP-----------HTYCGKGVCLLTGIMGAGCT-----ALVVAVVARKLE-LTKAEKHVHNFMMDTQLTKRIKNAAANVLRE 578
9 -8.500[S] COG1836 Predicted membrane protein  ali follow..  11  2.......................................................................................................................IVLALLGVLLLSVYAYKTKKLTLSGAISAFVVGALISFGLGFKGLLLLAIFFFTSGFWSRFYQERKENEITAKGSTRDGWQVLANGGFAAICALLFSILQDPCGFVASLAAANADTWASEVGPLAKRRPISAIGTAAAFAGSFIIVVVSI-LFSLTLAGFLGNLFDTLVGATNNDTVNAICTGTGALFGIVAGLIL.. 261
10 -8.160[S] KOG4491 Predicted membrane protein  ali follow..  12  54.........................................................................................................................WLFSVVVPVLIVSNGLKKKSLDHSGALGGLVVGFILTIAFSFFTSLLMFFLSSSKLTKWKGEVKKRLDSEYKEGGQRNFCNGAVPTELALLYMIENGPGELSLLAALACSAGDTWASEVGPVLSKSSPTVVGLVSSLLGGTFVGIAYF-IAFGGLAGLLGSIVDSYLGATDNNAVNLFSSVLIALLLPTAAWGF.. 332
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;