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Query: [H] COG0196 FAD synthase, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRLIRGIHNLPPNLSGCALTIGNFDGVHLGHQAILRHLRQKADALNLPVVVMLFEPQPREYFTGDAIPARLMRLRDKLHYLAQAKVDYVLCIRFNENFASQTAEEFIEDWLVKKLNVRFLSIGDDFRFGAKRQGDFALLQKSGEAFGFFVEDNHSFCCDELRISSTAIREALAEDDLAYAEKMLGKPYRILGRVAHGNKLGRTIGFPTANIPLHRQVNPVKGVYAVKVRLKNQEIYHGVANIGKRPTINGVVQLLEVHIFDFHSTIYGQCLEVEFCHKIRNEFKFPSFEALKEQIAQDVETAKHFFRTQQILast
1 -108.000[H] COG0196 FAD synthase  ali  100  1MRLIRGIHNLPPNLSGCALTIGNFDGVHLGHQAILRHLRQKADALNLPVVVMLFEPQPREYFTGDAIPARLMRLRDKLHYLAQAKVDYVLCIRFNENFASQTAEEFIEDWLVKKLNVRFLSIGDDFRFGAKRQGDFALLQKSGEAFGFFVEDNHSFCCDELRISSTAIREALAEDDLAYAEKMLGKPYRILGRVAHGNKLGRTIGFPTANIPLHRQVNPVKGVYAVKVRLKNQEIYHGVANIGKRPTINGVVQLLEVHIFDFHSTIYGQCLEVEFCHKIRNEFKFPSFEALKEQIAQDVETAKHFFRTQQI 311
2 -53.700[H] KOG3110 Riboflavin kinase  ali follow..  26  1................................................................................................................................................................................MPRADCIMRLPYFCRGQVVRGFGRGKQLGIPTANFPEQVVDNISTGIYYGWASVGSGDVHKMVVSIGWNPYYKNTKKSMTHIMHTFKEDFYGEILNVAIVGYLRPEKNFDSLESLISAIQGDIEEAKKRLELPE. 141
3 -23.300[R] COG1019 Predicted nucleotidyltransferase  ali follow..  11  2...............PKVAVGGTFQYLHDGHARLIEKAFEIAGDGKVYIGLTS------EMLQKNHSIDNYENRRVRLLEYIDEMEIPKEKYEITRLNDPCGP--------TVEEDFDYIVVSPETYPVALKINRIREKKGKNPLEIVYVEYV--MAEDGTPISSTRIAKGEIDRHGKMKRESQA.............................................................................................................................. 156
4 -16.500[R] KOG3351 Predicted nucleotidyltransferase  ali follow..  12  143...............HVTALGGTFDHIHDGHKILLSVSTFITSQ------RLICGITCDELLQNKKYKELIEPYDTRCRHVHQF----IKLLKPDLSVELVPLRDVCGPTGKVP-EIECLVVSRETVSGAETVNKTRIEKGMSAVHVVNVLGGREEDGWSEKLSSTEIRRLLK--SSASPTCTPQNPC........................................................................................................................... 304
5 -12.800[H] COG1056 Nicotinamide mononucleotide adenylyltransferase  ali follow..  16  8.................AFYIGRFQPYHFGHHAVITRIAEEVDELVIGIGSAQKSHEATDPF----------TAGERVLMLYNA-LENLPVRHYVLPIEDVRYNSIWVHHVASRTPRFDVVYSNN-----------PLVIQLFREAGFCVKESPLYVRER--YSGTEIRRRMIAGE--KWEHLVPKPVAETIKDIDGITRLRNVSASDSNFSL.................................................................................................. 177
6 -12.200[H] COG0414 Panthothenate synthetase  ali follow..  17  1MLIIETLPLLRQQIRRRVALVPTMGNLHDGHMKLVDEAKARAD-----VVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLV----FAPSVKEIYPNGTETHTYVDVPGLSTMLEGAS--FGEKDFQQLALIRKMVADMGFDIEIVGPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAGERDLDEI------IAIAGQELNEKGFRADDIQIRDADTLLEVSETSKRAVILVAAWLGDARLID.................................................. 276
7 -12.100[H] COG0669 Phosphopantetheine adenylyltransferase  ali follow..  18  1.........MSQKRLSRVIYPGTFDPITNGHLDLIERAAQMFDE-----VIIAVAASPSK--------NTLFTLEERVEFARQVHLDNVSAKGFSGLLVDFAKAEKANVLI------RGLRTTVDFEYEFGLTNMYRRLMPGLE------SVFLTPAEEHAFISSTLVREVAIHGG-AIVANALHQKKKI......................................................................................................................... 164
8 -10.300[H] KOG3042 Panthothenate synthetase  ali follow..  12  37MKIFHTVEEVVQRFRETIGFVPTMGCLHSGHASLISQSVKENT-----YTVVSIFVNPSQFAPTEDLDNYPRTLPDDIKLLESLKVDVLFA-GLSEKLEGKTRPNFFRGVATVVTKLFNIVMADVAYFGQKDIQQFIVLQCMVDELFVNTRLQMPIVRNNNGLALSSRNKYLCPESLKISENLYRGLKAAENAIRRLAPGGRLSRSEIIDTQIWAPYVDSHDFKIDYVSLADFKTLDELSDVENTSEQQPIVISCAVYVTDREKPDTVVRL........................................ 339
9 -9.060[MI] COG0615 Cytidylyltransferase  ali follow..  17  89..........PEGRPVRVYADGVFDLFHIGHMRQLEQAKKVFPNVHLIVGLPN----DQLTHRLKGLT--VMNDKERAEALRHCKVDEVL----------ENAPWVITPEFLEEHKIDFVAHDDIPYASDDSGDIYLPVKKVGK----------IPTKRTEGVSTSDLITRIIRDYDQYVMRNLARGVN.......................................................................................................................... 243
10 -8.600[H] COG1057 Nicotinic acid mononucleotide adenylyltransferase  ali follow..  11  120..........EGKIPLVLVACGSFSPITYLHLRMFEMATDTIQEQTNMELVAGY-----SPVNDHYKKEGLAPAYHRVRMCE-------LACERTSSWLMVDAWESLQPSYTCTARV-MLLAGGDLSMGEPGVWSDKDLHHILGKFGCCIVERTGSDVWANDISSTKVRLFIRRGM----------RYLLPNSVIQ--------------------YIERYALYRDAEPVKTIFYQSPFVR--MEP................................................................. 365
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.