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Query: [R] COG0433 Predicted ATPase, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSDHALGSVTQGSLSKGLEVRLHADVSVEEMRVGKFLVIQGRRSRFFCLLTDVSLGTANPRILANPPNINDDFLIDVLAGSGTYGTLELAPMLMLTESEKDSSYGESSVEQMNGQGDRQSNGNGLASYQANSNADVELLPVKTIPAHFSQVFEASERDFRLVFGWEDDPFRRNFAIGEPLDMAVPVCLDLDRFVERSNGVFGKSGTGKSFLTRLLISGIIHKQAAVNLMFDMHSEYGWEAMREGKTVSTVKGLRQLFPGEVEIFTLDAESTKRRGVRGAQELYLSFDQIEIEDIRLVGFELGLSEAALDNANILFSEFGSSWISRLLVMSNEEIKVFCEEKQGHPGSIMSLQRKLKRLENLKYLKQVSTHNYIDQLLQCLEAGKHVVIEFGSQSNLLSYMLATNMITRRIHSIYVKKAEKFLQTKHVGDRPRQLVITIEEAHRFLDSAIVHQTIFGTIAREMRKYFVTLLVVDQRPSGIDNEVMSQIGTRITCLLNDEKDIEAIFTGVAGGQNLRSVLAKLDSKQQALVLGHAVPMPVVVRTRPYDQQFYSEIGCQDWPNKTDAEVLAEAAIAREDLGFLast
1 -146.000[R] COG0433 Predicted ATPase  ali  100  1MSDHALGSVTQGSLSKGLEVRLHADVSVEEMRVGKFLVIQGRRSRFFCLLTDVSLGTANPRILANPPNINDDFLIDVLAGSGTYGTLELAPMLMLTESEKDSSYGESSVEQMNGQGDRQSNGNGLASYQANSNADVELLPVKTIPAHFSQVFEASERDFRLVFGWEDDPFRRNFAIGEPLDMAVPVCLDLDRFVERSNGVFGKSGTGKSFLTRLLISGIIHKQAAVNLMFDMHSEYGWEAMREGKTVSTVKGLRQLFPGEVEIFTLDAESTKRRGVRGAQELYLSFDQIEIEDIRLVGFELGLSEAALDNANILFSEFGSSWISRLLVMSNEEIKVFCEEKQGHPGSIMSLQRKLKRLENLKYLKQVSTHNYIDQLLQCLEAGKHVVIEFGSQSNLLSYMLATNMITRRIHSIYVKKAEKFLQTKHVGDRPRQLVITIEEAHRFLDSAIVHQTIFGTIAREMRKYFVTLLVVDQRPSGIDNEVMSQIGTRITCLLNDEKDIEAIFTGVAGGQNLRSVLAKLDSKQQALVLGHAVPMPVVVRTRPYDQQFYSEIGCQDWPNKTDAEVLAEAAIAREDLGF 579
2 -25.800[U] COG3451 Type IV secretory pathway, VirB4 components  ali follow..  12  172....................................................................................................................................................................................YRNQLAFIDIMNNTNYNMAVCGTSGAGKTGLIQPLIRSVLDSG-GFAVVFDMGDGYKSLCENMGGVYL-----------DGETLRFNPFANITNIDQSAERIRDQLSVMASPNGNLDEVHEGLLLQAVRAAWLTKKN--RARIDDVVDFLENRTSEQYAESPGIRSRLDEMIVLLNQYTAAGTYGRYFNSDEPSLRDD----ARMVVLELGGLDRPSLLVAVMFSLIIYIENRMYR-----------TPRNLKKLNVIDEGWRLLDKNRKVGDFIEKGYRTARRHTGAYITITQNIVDFARAAWGNSSYKIILKQSAKEFAKYNQLYPDQFPQLHREMIEKFGAASFLLQVENHSSWHRLFVDPLSRAMYSSDGPD....................... 539
3 -21.900[U] COG3505 Type IV secretory pathway, VirD4 components  ali follow..  10  142....................................................................................................................................................GTARWAGFGEMRHAGYLQRYNRIKGPIFGKTCGPRWFGSYLTNG--QPHSLVVAPTRAGKG--VGVVIPTLLTFKGS-VIALDVKGELFELTSRGDAVFKFSPLDPERRTHCYNPVLDIAALPPERQFTETRRLAANLITAKGKGAEGFIDGARDLFVAGILTCIERGTPTIGAVYDLFAQPGEKYKLAGNDTKILTSYTSVLGDGGLNLWADPLVKAATSRSDFS--VYDLRRKRTCVYLCVSPNDLEVVAPLMRLLFQQVVSILQRSL-------PGKDERHEVLFLLDEFKHL------KLEAIETAITTIAGYKGRFMFIIQSLSALTQNFLSNTGVQVFMATADDETPTYISKAIGDYTFKAREQVRLLDDNNEIVLIKGHP-PLKLR...................................... 574
4 -15.000[D] COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins  ali follow..  15  415..............................................................................................................................................EVPNQEVAIVTL--REVLDSPQAKADRNVLSVGLGRDIS-GEPVFAPLNKM---HLLVAGATGSGKSVCINGIITSILLKAKPKLMMIDPKNVY---------------------------------------------------------------------------------------NGIPHLLTPVVTEPKKASQALKKVVAEMERRYDLFSHSG--------------------------------------------TRNIEGYNEMITRQNEKEDAKQPTLPYIVVIVDEADLMMVASGDVEDSIARLAQMARAAGIHMILATQRPS-ITGVIKANIPSRIAFGVSSQTDSRTILDTGGAE--------KLLGRGDMLYLPMGATKPTRVQLSDEEVETIVEFVVAQQKAQYAEEMTPTEETKVTEKV. 719
5 -12.900[R] COG4637 Predicted ATPase  ali follow..  2........................................................................................................................................................................TETKDKQLSRIVLKGFKSIAKCDLEISRVNILIGANGAGKSNFIGFFVGQLVEENLQVFV--SRQGSPDALLHFGRKTTEHLEFQLYFGNNGYFATLEPTQDNRLMFARESFWWNMSGEHEIGRGHFETKVLTSTRTGIDEYVLSAMQQWRVYHFHDTSESAYIKQPHGINDNAYLRPDARNLASFLYLLRNSYPASYQRIVKTIRLVAPFFGDGQDIPFKAYLLSDGTLRFMCLATVF-------------------QPEDLQPETILVDEPELGLHPY-----AITVLASLMRTASKQVIVSTQSI-----ELLNQFEAKDVIVVDRSEGSSYLRRLNQGDRIHFTG.............................................................. 342
6 -10.300[L] COG3593 Predicted ATP-dependent endonuclease of the OLD family  ali follow..  10  1.............................................................................................................................................................................MHLRQLDVLGFRGIHRLSIHFSADMVLIGENMWGKSSLLSAL------------LIFNPEKALYQFTLRDFHIPAEQTEPVRHLILLFTFAESEKNEDSMEYHLPYLQHHLLVDHLDGYQRLYLRVEGQINANNEVNTTYAFLNEKGEPIRFRDARLNRAHHSFRFIRTEVQDETQDEIRAVSDLLCYYFLNHKNMTEIKQDTTLLWHKAKSLCTKLKQDETHRLRKKLFFSLASLF----------VRNQRIHFGRFTRPIILFEDPDARLHPRMV-----AIMWELVSYLPVQRITTTNSV-----ELLSQVNLNAICRLVGKEDFRRLTFHIHHNRSLA-----LFSRMWILVEGEVWILSELAKL..................................... 370
7 -9.920[R] COG4128 Zonula occludens toxin  ali follow..  23.......................................................................................................................................................................................................................................................................................................................................................................................LLPAIKSGRHIITNVRGLNLERMAKYLKMDVSDISIEFIDTDHPDGRLTMARFWHWAR-FLFIDECGRIWPPRLTVTNLFEVAFDMHRHHGWDICLTTPNIAKVHNMIREAAEIGYRHF-SGQMDSHALTRQVKKIPSPIFKMYASTTTGKA.................................................... 212
8 -9.600[R] COG3950 Predicted ATP-binding protein involved in virulence  ali follow..  2...................................................................................................................NEPTRIPKYVKDKIRQAKQGDLYSSFTVSEYYYDGEVLERDIEQSELYNVSRIINNAKIRLRNISLYDYKKFSKLKTSSEKNTTIIGNNGSGKSTILESISDNIRIQNNNNYKFQDSEINIHSISGQTIVRCILEIENDFSFSCSLTKNRENISRKVSSELEEFKALARMYQRSNELDNNTLEFKANDSITKEEIEYLLSKTDNKEKIGSLISQLLEKKNNYNNNEDREIRQQKVIQESIKTFVS-DIDQVKISRTPHLDMTVIKNGSEISIFNLSQ-GEKTLIALVSDIARRLV----------ILNPSLENPLNGYGIVLIDEIDLHLHPK--QQTIVQKLE---NTFNIQFILSTHSP------VLTTVTSEQIKIINELDYRFKLLSPTSNPFGKNASDA--LAIMETSESPLVHSEEILALIKKYESLVKRGQEDCRKTKEIKKRIES........... 509
9 -9.420[S] COG3421 Uncharacterized protein conserved in bacteria  ali follow..  54.....................................................................................................................................................PFFEWQKSALENFVIFDRASKLKDFP--------------------THLLFNMATGAGKTMMMAALILYYFEKGYRHFLFFVNQ------------------------------------------------------------------------------------------NNIVDKTENNFIDPAHAKFLFTEKILQGDTVIP--------------RKVEMFSPHSDGIEIKFTSIQKLYNDIHTERENQTTLADLHK-------------------LNLVMLGDEAHHLNAQTKGKHMVLELLLNKNGNPGQNVLLFTATLPE-NADVQQKYADKIITKLKEFLQKGYTKE......................................................................... 302
10 -8.660[S] COG4938 Uncharacterized conserved protein  ali follow..  10  2...............................................................................................................................................................................INEVTLRNFKCYKNQLFELANLTVFCGNNSSGKSTVIQSLL--ILQNNFSNKLELRGDGSYNDLHNRNADEDSLSILIDEEAPLPLLDFSDKTVLHKLRELYEDEFIYLHAERWGPRSSYPYSTRRRSQNWLGTNGEYAPQVLELVVKNIQTMPSDDVRIHPNLTDGSVVGIAQNLFEWMGEISPGVFIKAQAFKHADITTNQYTFGGSYRAVNVGFGLSYVLPIVLALLVTKP-------------------------LVIIEEAHLHPRGQSYLGRLIALAAEAGVQ----VVVETH-----SDHIINGIRLMPRLGKVQDKNLLFYQVINEDVGTTTVKKIIVNAQGQ..................................................... 349

FFAS is supported by the NIH grant R01-GM087218-01
1 4 0 5 9 4   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Reed JC, Doctor K, Rojas A, Zapata JM, Stehlik C, Fiorentino L, Damiano J, Roth W, Matsuzawa S, Newman R, Takayama S, Marusawa H, Xu F, Salvesen G, Godzik A.; RIKEN GER Group; GSL Members. Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res. 2003 Jun;13(6B):1376-88.