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Query: [P] COG0672 High-affinity Fe2+/Pb2+ permease, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRIWQKFLLLFCCWVLSGPLVWASTDYSLWVNDIQSRLDKTAQLYQQQKTDEARAMVQMAYFEVFENLEGPIRINISAQKSFQMEAAFGEIRRMIGEGKSQADVDNKINWLKGELTGVLPVLVDGHKLTAEQQHAAYENSDIAVYWQQSFRIIDDLLAQAISEYQDGKYAEASKSVQQAHYQGFKNSEMEMSVRGNRSAQQAAEINQQFTALIDLARQPDKMTEVAYRVTGLLHTIEDILPGLPTTREQQQITVDQPISSDAIPDTQANADWAQVSSKINQAVTEAIGQYQQGKITPAMMAVQDAYFDLFEASGMENKVGSRDAAFKSTLEGHFTRLVGLMKAEKPVEQLQAEAVALQKDLVNAAEMLGDGGETDWSLFVYSLLIIVREGLEALLIVAAIVAYLVKNNHQDKLPLIRQSVVVALIASVLTAFIFQWLFANSGQSRELLEGFTMMIAVVMLFSMSYWLLSKAEARNWKAYLEGKFAKSLSSGSIIGLWLTSFLAVYREGAETVLFYLALIGDANTTSGHLSVLAGFGVGCVILLVAYLVMRFTVVKLPLKPFFIFTGGFMYLMAFVFAGKSVLELIEGKLFEPTLLPGVPEISWLGIYPYVETLIPQGVLLIAALVALWVMQWRSRTVHRLast
1 -114.000[P] COG0672 High-affinity Fe2+/Pb2+ permease  ali  100  1MRIWQKFLLLFCCWVLSGPLVWASTDYSLWVNDIQSRLDKTAQLYQQQKTDEARAMVQMAYFEVFENLEGPIRINISAQKSFQMEAAFGEIRRMIGEGKSQADVDNKINWLKGELTGVLPVLVDGHKLTAEQQHAAYENSDIAVYWQQSFRIIDDLLAQAISEYQDGKYAEASKSVQQAHYQGFKNSEMEMSVRGNRSAQQAAEINQQFTALIDLARQPDKMTEVAYRVTGLLHTIEDILPGLPTTREQQQITVDQPISSDAIPDTQANADWAQVSSKINQAVTEAIGQYQQGKITPAMMAVQDAYFDLFEASGMENKVGSRDAAFKSTLEGHFTRLVGLMKAEKPVEQLQAEAVALQKDLVNAAEMLGDGGETDWSLFVYSLLIIVREGLEALLIVAAIVAYLVKNNHQDKLPLIRQSVVVALIASVLTAFIFQWLFANSGQSRELLEGFTMMIAVVMLFSMSYWLLSKAEARNWKAYLEGKFAKSLSSGSIIGLWLTSFLAVYREGAETVLFYLALIGDANTTSGHLSVLAGFGVGCVILLVAYLVMRFTVVKLPLKPFFIFTGGFMYLMAFVFAGKSVLELIEGKLFEPTLLPGVPEISWLGIYPYVETLIPQGVLLIAALVALWVMQWRSRTVHR 639
2 -14.600[S] COG4280 Predicted membrane protein  ali follow..  19  4........................................................................................................................................................................................................................................................................................................................................................................................SIFLAALGSTSVEFFEVVAIAYAI-------GSSGYVKEAIWGSIVGLIAVLSVAIALGTGLQFLP-----LQPLQIVIGGLLLWFGWGWA-KKSVRRLATGRRAGWIDDQVLEKEGIVLFLIMTKSVALEALEIFVIVITLGLATSA-----EAIAATGFALLLSLVFVIFLHPYLVKLPEVLIKLGAGIMLSAMGTFWLGEGV.......................................................... 203
3 -12.700[S] COG2119 Predicted membrane protein  ali follow..  21  2........................................................................................................................................................................................................................................................................................................................................................................FVYGSIINPCPTEHVMSVLAISITVALAEIGDKTQLLSLLLAS-----RYRKPIPIIAAIFLATLANHALAAWLGVVVA-----DYLSPDILKWVLVVSFLAMAGWI------------LIPDKLDGEESISTRGPFVASFIAFFAEGDKTQI--ATSILGAQYADALSWVIVGTTLGMLLANVPVVLIKLSADKMPLGLIRKVTAGLFLLMALATA.............................................................. 198
4 -11.300[S] COG4393 Predicted membrane protein  ali follow..  9  1..............................................................................................................................................................................................................................................................................................................................................................................................MNYFFTSLLQTLLPFALLLGCAWSYHPQVNMKSRLWLALLCFVAGAILSIYL--------PKSQRINLVLSAWIITSLLLFCLSQYWHNKT------------------TSFWHVLLSFIAGLLWGKDPNLSA--ITHTDVINTDFILHSSAIILAILLAIFVASWLSSKIQHKLTALAPLLTYLIVILLLIPQSAELMLSLMKLQLLDLTKA----RLSFVAKAGNLTNFFNYLQSAILLIIMLSFWFRVHLARQH 231
5 -10.900[S] KOG2881 Predicted membrane protein  ali follow..  11  32.....................................................................................................................................................................................................................................................................................................................................................TVDVKLDETAVVEKTEEKEAQKEHKKISSEDISFYHGFLASFVIVVSELGDKTWFIAVIMS------MRHSRLTVFSGAMGALALMTVLSACLGWITQV------IPRAVTYYLSTALFALFGLKMLGKFEMLEGGGGVASQSETRKIFLFTSRIFIEAFSLTF-EGDRSQLTTIIL----GARENIAGVIGGGILGHALCTGIAVIGKIVAQRISVRTVTLIGGVVFLLFALSALFINDIE........................................................ 292
6 -10.300[S] COG2836 Uncharacterized conserved protein  ali follow..  9  3........................................................................................................................................................................................................................................................................................................................................................................................PDYLGAWVVGLLGAGHCLGMCGGISALLTLDPSKRLLSYALIGGIVGGITASLT----------ELIDVQSALVWLRIFAAVLMIVLGLYIGREKVGQKIWRWISPLGKTLLPLKKQWHALPFGLVWGW--GLVYSMLTWSAVAGSFSQGALIMLSFGFGT-LPAMLASGWGANKLMHWQNSHLFRQCAAILVIGYGLFTAYDAVKLMINLG................................................... 224
7 -9.780[P] COG0861 Membrane protein TerC, possibly involved in tellurium resistance  ali follow..  13  6...................................................................................................................................................................................................................................................................................................................................................................................DPSIWAGLVTLIVIELVLGIDNLVFIAILAEKLPPGQRD---RARITGLILAMIMRLLLLASISWLVTLT-----SVQALSFSARDLIMLFGGFFLLFKATMELNERLEGKDSANPTQRKGAKFWAVVAQIVV----LDAIFSLDSVITAVGMVDHLAVMMAAVIIAISLMLLASKSLTRFVNNHPT--IVILCLSFLLMIGFSLVAEGFG......................................................... 206
8 -9.380[U] COG2095 Multiple antibiotic transporter  ali follow..  10  7........................................................................................................................................................................................................................................................................................................................................................................................AIFLQFFLGLV---VNPVGIMPVFVSLTGHMTLEEKNKTAATANIAVAIILIIALLAGQMLLDLFSISLDSFR----VAGGLLLLSIAFSMMSGKLG---EDKQNKQEKSEYISREQIAVVPLAMPLMAGPGAISSTIVYG------SRYPNMLDTLGIILTVVAFSFCSWLLFRSAPYI-INVITRIMGLILGALGIEFIANGLRNL....................................................... 207
9 -9.010[R] COG1279 Lysine efflux permease  ali follow..  10  9..........................................................................................................................................................................................................................................................................................................................................................................................LALGAAMILPLGPQNAFVM---------------NQGIRRQYHIMIALLCAISDLVLICAGIFGMQSPWLLALVTWGGVVFLLWYGFGAFKTAMSSNIELASAEVLKQGRWKIIATML-AVTWLN--HVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWFFGLAILAAWLAPRLRTAKSQRVVGCVMWFIALQLARDGIAHAQAL.................................................... 209
10 -8.600[P] COG4300 Predicted permease, cadmium resistance protein  ali follow..  12  7........................................................................................................................................................................................................................................................................................................................................................................................QNVVTSIILYSGTAVDLLIILMLFFA---KRKSRKDIINIYLGQFLGSVSLILLSLLFAFVLDYI---SKEILGLLGLIPILL----------KVLLLGDSDGEAIAKEGLRKDNKNLIFLVAMITFASC-GADNIGVFVPYFTTLNLANLIVALLTFLVMIYLLVFSAQKLAQVPSVGETLEKY--------WFVAVVYLGLGIYILVENNSFD................................................ 201
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 9 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Jaroszewski L, Li W, Godzik A. A segment alignment approach to protein comparison. Bioinformatics. 2003 Apr 12;19(6):742-9.