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Query: [O] COG0760 Parvulin-like peptidyl-prolyl isomerase, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MMDNLRAAANNVVLKIILALIMLSFILTGVGSYLIGGSNDYAAKVNDQDISRAQLEQAMQSERGRLQQKLGEQFSVLAANEGYMQQLRQQVLGQLINNVLLDQYARKLGLTVSDEQVKESIRQIPDFQTGEHFDNNRYLALINQLGYTPEQFAQLQRQQLINQQLLKAFSDTGFVLPIEVQAMSALVLQQRDVRLATLDLKALQAEQKVTDEELQAYYDQNKHNFIAPEQMKVSFIAMDAAAMQSNITVTEEDIAAYYDQNRSSYTQPERRNYSVIQFKTEVEAKAALDELKKGADFAVIAKEKSTDIISRNNGGELGWLEPETTPDEVKAANLSEKGQLSDVIKSSVGYLIVRLNDIKPELVKPLSEVHDELAKKLKQEKALDAYYALQQKVNDAATSDNESLASAEEVAGTKAQQTGWFTRDTVPAEINFKPVVQAIFDGRLVGENGSAGSNSEVITVDGDRAFVIRIDGHKPEGIEPFDQVRDQISELVKRQKAEQQARVDGEKILTALKQGKGEEAMKSAGISFGEKKTLSYASVDDQLMQTIFALAHPQKDQPVYGLSQDRQGNIVLIELLSVTPGKLQESETKIFIEKMQEESVSMIFDALMANLHKQATIKIGPAEQQQPQLast
1 -158.000[O] COG0760 Parvulin-like peptidyl-prolyl isomerase  ali  100  1MMDNLRAAANNVVLKIILALIMLSFILTGVGSYLIGGSNDYAAKVNDQDISRAQLEQAMQSERGRLQQKLGEQFSVLAANEGYMQQLRQQVLGQLINNVLLDQYARKLGLTVSDEQVKESIRQIPDFQTGEHFDNNRYLALINQLGYTPEQFAQLQRQQLINQQLLKAFSDTGFVLPIEVQAMSALVLQQRDVRLATLDLKALQAEQKVTDEELQAYYDQNKHNFIAPEQMKVSFIAMDAAAMQSNITVTEEDIAAYYDQNRSSYTQPERRNYSVIQFKTEVEAKAALDELKKGADFAVIAKEKSTDIISRNNGGELGWLEPETTPDEVKAANLSEKGQLSDVIKSSVGYLIVRLNDIKPELVKPLSEVHDELAKKLKQEKALDAYYALQQKVNDAATSDNESLASAEEVAGTKAQQTGWFTRDTVPAEINFKPVVQAIFDGRLVGENGSAGSNSEVITVDGDRAFVIRIDGHKPEGIEPFDQVRDQISELVKRQKAEQQARVDGEKILTALKQGKGEEAMKSAGISFGEKKTLSYASVDDQLMQTIFALAHPQKDQPVYGLSQDRQGNIVLIELLSVTPGKLQESETKIFIEKMQEESVSMIFDALMANLHKQATIKIGPAEQQQPQ 628
2 -41.200[O] KOG3259 Peptidyl-prolyl cis-trans isomerase  ali follow..  16  2................................................................................................................................................................................................................ADEEKLPPGWE---------KRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVEALELINGYIQKIKSGEDFESLASQFSDCS-SAKARGDLGAFSRGQMQKPFEASFALRTGEMSGPVFTDSGIHIILRTE............................................................................................................................................................................................................................................................................... 163
3 -6.870[M] COG4775 Outer membrane protein/protective antigen OMA87  ali follow..  9  1............MKKLLIASLLFGS---------------TTAFAAPFVVKDIRVDGVQAGTEGSVLATLPVRVGQRATDNDIANVVRKLFLSGQYDDVKASREGNTLVVTVMPKPVISNV----VIDGNKSIPDEAIKQNLDANGFKVGDVLNRAKLEEFRKGIVEHYNSVGRYNAKVEAIVNTLPNNSAEIKIALFKEIIFEGNQAFSSSKLEDQMELQTDAW---------WKLFGNKFDQTQFNKDLETLRSYYLDRDTDIKLSDDKKEARVIIKVKEELAPILDAIQLNGLFRRANVLEVEQRIKSK--GERGYATFDEQDKTISLDFIVEAGK------------TVRQIRFEGNTSSADSTLRQEMRQQEGAWLSSELVELGKLRLDRTGFFESVETKPGSDQVDVIYKVKE................................................................................................................................................................................................................. 415
4 -5.620[P] COG3119 Arylsulfatase A and related enzymes  ali follow..  7  14................IVVIMLDDVGPALPDTFGGVIETPTLSRLAQDGLSYNRFHNAAMCSPSRAALLTGRNHHRVGNGQIAELANDWDGYTGRIPRTSVAKVLGYYGYATA----KWHNTPANETTAVGPYTDIGFDYFYGFLAGESSQWEPAVVENTVRVDPSHG-KEGYHFTEDMTNKAVTWMKQVHALTFMYWAPGAAHGPHHIFKDWADKYFDDGWDAMRERIYARQKQLGWIPQNTQLTPRPDTLSGWEDIPEDEKPFQRRLMEVFAGYTEHADVQAGRLLEALDELGIRDNTLIFYVWGDNGSSAEGQAGWAWAGSTPHRSTKLVAAHFGGTRTPLVVSWPGKIKPDQTPR-SQFHHLNDIVPTIYDVLDIQPPKLVDGISQDPLDGVSMTDSPEASGQKKEQYFEIMGSRAIYQDEWIASVFGPRIPWKAGLDPAIFKWSPDNDLWELHDLSQDYSQAKNVAADHPEKVE-------ALKRAFGVQAEANKVFPVGGGLWSAVFHPEDAPSNPATEFQFTQDVVGVPEFTAPKVGARSNLVTIEAELRPDSEGVLYALGA........................................................... 618
5 -5.350[R] KOG4700 Uncharacterized homolog of ribosome-binding factor A  ali follow..  13  98.....................................................................................GLLYKALTDLLCTPEVSQELYDLNVELSKVSLTPDFSACRAY--LSAEQNAHMEAVLQRSA-------AHMRHLLMSQQTLRNVPPIVFVQDKGNAALAELDQ--------LLAVADFGPRDERDNFVQNDFRDPDAPQ-TTEPTTSSSLCGIDHEALNKQIMEYKRRKDKGLGGLVWQGQVAELTT------QMQKGRKRAKPRLEQDSSLKSYLSGEEVE................................................................................................................................................................................................................................................................................................................................. 302
6 -5.100[A] KOG0117 Heterogeneous nuclear ribonucleoprotein R (RRM superfamily)  ali follow..  12  2......................................................................................................ESNHKSGDGLKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERFIGKLPRDLFEDELIPLCEKIGKIYEMRM--MMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKT-------KKREEILSEMKKYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSN-REDAVEAMKALNSPIEVTLAKPVDKDS................................................................................................................................................................................................................................................... 308
7 -5.040[K] KOG2251 Homeobox transcription factor  ali follow..  17  44..........................................................................................................................................................................................RKQRRE---TTFTRAQL--------DVLEALFA--KTRY--PD-------IFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNG................................................................................................................................................................................................................................................................................................................................................................. 111
8 -5.020[R] KOG0488 Transcription factor BarH and related HOX domain proteins  ali follow..  11  167..........................................................................................................................................................................................................................KKPRTSFSRVQICELEYLA-ERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEERE----AERQQASRLMLQLQHDAFQKSLNDSIQPDPLCLHNS.......................................................................................................................................................................................................................................................................................................................... 266
9 -4.930[K] KOG0484 Transcription factor PHOX2/ARIX, contains HOX domain  ali follow..  20  88..........................................................................................................................................................................................RKQRRI---TTFTSAQL--------KELERVFA--ETHY--PD-------IYTREELALKIDLTEARVQVWFQNRRAKFRKQER...................................................................................................................................................................................................................................................................................................................................................................... 150
10 -4.910[G] KOG0563 Glucose-6-phosphate 1-dehydrogenase  ali follow..  12  51..........................................................................................TIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMDA----------------LHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDL------------------QSSDRLSNHISSLFREDQIYRIDHYL--GKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFD--------EFGIIRDVMQNHL-LQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEES--ELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELR..................................................................................................... 459
FFAS is supported by the NIH grant R01-GM087218-01
1 4 2 0 2 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Functional differentiation of proteins: implications for structural genomics. Structure. 2007 Apr;15(4):405-15.