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Query: [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSWSVTLNQLIEVLLARPVNISEAALTQVSSGIQTDTRMIKPGEVFLAFRGEKFDGHEFISSAIARGAIAAIVDDDYENPGLPVLQVSNTLEAYQKLGRWWRDRFDIPVIGVTGSVGKTTTKELIAAVLGTKGNVLKTYGNYNNEIGVPKTLLELNAEHDYAVIEMAMRGRGQIAELAQIARPTIGVITNVGTAHIELLGSEEAIAEAKCELLAEMPKDSVAILNHDNPLLMATAAKFWSGEVLTYGLSGGDVQGSLVDNAIVEVAGLRLPLPLPGRHNATNYLAALAVAKVLGIEWSSLQAGVSVNMPTGRSQRFSLPNDVLILDETYNAAPEAMLAALQLLADTPGKRKIAVLGAMKELGERSAQLHQRVGETVRNLKLDGLLVLVDGEDAEAIARSAEGIPSECFATHADLVARLTTFVQGGDRLLFKAAHSVGLDRVVSQLRAEFSNLast
1 -131.000[M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase  ali  100  1MSWSVTLNQLIEVLLARPVNISEAALTQVSSGIQTDTRMIKPGEVFLAFRGEKFDGHEFISSAIARGAIAAIVDDDYENPGLPVLQVSNTLEAYQKLGRWWRDRFDIPVIGVTGSVGKTTTKELIAAVLGTKGNVLKTYGNYNNEIGVPKTLLELNAEHDYAVIEMAMRGRGQIAELAQIARPTIGVITNVGTAHIELLGSEEAIAEAKCELLAEMPKDSVAILNHDNPLLMATAAKFWSGEVLTYGLSGGDVQGSLVDNAIVEVAGLRLPLPLPGRHNATNYLAALAVAKVLGIEWSSLQAGVSVNMPTGRSQRFSLPNDVLILDETYNAAPEAMLAALQLLADTPGKRKIAVLGAMKELGERSAQLHQRVGETVRNLKLDGLLVLVDGEDAEAIARSAEGIPSECFATHADLVARLTTFVQGGDRLLFKAAHSVGLDRVVSQLRAEFSN 451
2 -48.200[M] COG0769 UDP-N-acetylmuramyl tripeptide synthase  ali follow..  21  1....MKLRELLATVDSVEN-LPPVLADAEVKGIKTNSHACGAGDLFIGMPGTRVDGGEFWPSAIASGAIAAIVSPQAVHDEAVVISSNNMTKACAAIAAAFYGY-KLKLVGVTGTNGKTTTTHLIEFFLTKAKLSTALMGTLYTRWP-AVELQQQNAGCEFGVMEVS-SHALAQGRVLGCP--EVGVFSNLTQDHLDYHSDMEDYFAAKALLFSPEYLKGRAIINADDTYGQRLIKALSPEKVWSYSVNDADLWMSDLGTIHTPEGNVSFRSPLVGQYNLENLLAAVGAVLHLGLNLQLIANAIPEFPGVPGRMERVQINPISVIVD-YAHTPDSLENLLKAARPFIPGRMICVFG-----GDRDRTKRPKMGKIVAELA-DLAFVTSDNPRTEDLAGIPDTVQPTVIGDRAIAIRTAILQAQPGDGVLLAG-KGHEDYQILGTEKIHFDD 482
3 -34.100[M] COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase  ali follow..  21  8..............................................ILVAGLGGTGISMIAYLRKNGAEVAAYDAELKPERVSQIGISERQPDIEELLADIVNRRDDKVIAITGSNGKTTVTSLVGYLCIKCGLDTVIAGN----IGTPVLEAEWQREADVWVLELSSFQLENTESL----RPTAATVLNISEDHLDRYDDLLDYAHTKAKIFRG---DGVQVLNADDAFCRAMKR--AGREVKWFSLEHEADFWLERETGRLKQGNEDLDIPLQGLHNAANVMAAVALCEAIGLSREALLEHVKTFQGLPHRVEIGEKNGVVFIDDSKGTNVGATAAAIAGLQ----NPLFVILG-----GMGKGQDFTPLRDALVGK-AKGVFLIGVDAPQIRRDLDGCGLNMTDCATLGEAVQTAYAQAEAGDIVLLSPARSEVFIEAFKAL...... 445
4 -29.000[M] COG0773 UDP-N-acetylmuramate-alanine ligase  ali follow..  19  51.............................IGGVGMSGIAEVLHNLGFKVSGSDQARNAATEHLGSLGIQVYPGHTAEHVNGADVVVTSTAVLMLAELMRFRDG------IAIAGTHGKTTTTSLTASIL--------GAAGLDPTFVIGGKLNAAGTNARLGKGEYIVAEADESDASFLHLTPIMSVVTNIDEDHMDTYGSVEKLHQAFIDFIHRMPFYGKAFLCIDSEHVRAILPKV-SKPYATYGLDTADIYATDIEMKGHEQGSFEVVLNMPGRHNVLNALAAIGVALEVGASVEAIQKGLLGFEGVGRRFQKYNGGTALLVDD-YGHHPVEMAATLSAARGAYPEKRLVLA----HRYTRTRDLFEDFTKVLNTVDALVLTEVADSRALARAIRVLGKLEPIYCENVADLPEMLLNVLQDGDIVLNMGA---SINRVPAALLELSKQ 505
5 -20.500[H] COG0285 Folylpolyglutamate synthase  ali follow..  15  20......................................................................................IDMGLERTSEVKKRMKLEPQCPVVVVAGTNGKGSVCAYLTQIYKQAGYKIGTLTSYNERIEISLTYFEFREQVDVMILEVGLG--GRLDA-VNAFDGDCAVVTSVDLDHQAFLGTVEQVGFEKAGVFR----SGKPAICGQNPAPKSLLSHAEAIGAFEFHAMENIQWNYRFRPQHSDDPARNRNPALRGTYQLSNAACALTVLECLNVDIGAIKRGLLLVENPG-RFQVLPGRPLTVLDVGHN--PHAARALRRSLINLAFAQKRTAV-----FSMLSDKDIDGVLETVKDQFDEWYIAPLDVPRGQNKLHEHSIENIQTFAAVREAYRAAASKAGENDRIVVFGS.................. 413
6 -17.800[H] KOG2525 Folylpolyglutamate synthase  ali follow..  15  59......................................................................................MVEMRHWLRCIGYQPSDLNRLNVIHVAGTKGKGSTCAFTSSILQQIQKSGERSIPKC--IGMPLTLMAWSENVDAAIIEVGIG--GEYDSTNLIEKPYATAVTSLGLDHTSLLGTIAEIAWQKAGIY----KESAIALTCEQA-----------PEAMNVLKNRAAERNTSLKVVIPPAELTPDMIGLSGVHQLGNTSLAVSLVQEFPYQDPAILDGLKYVKWPGRCQIEEINNIKWCFDGAHT--KESLEATGLWLASKDADARILLFNQQSRDDPIARSFLKGLESSGTGISFTHVIFSTNVTWKDAGYNPGTTSEATVAPTIQEAIETVMSIKQRNTFVCVTGSLHL-TGGVFVVLDQAV.. 504
7 -8.860[S] COG3367 Uncharacterized conserved protein  ali follow..  15  63..........................DVPVVSSVEKAKEMGAEVLIISNPGGYLQIATLVKKALSLGMDVISGLHFKISQQTEFTRIIDIRIPPLELDVLRGGRKKIKVVGVFGTDGKRTTAVQLWERALEKGIKAGFLATGQTGIVVEKAVLKLEKTGKEIVFVEGQGALRHPAYLLYGSNPDVVFLHDPSRDHFESFPEIPKKFEEERRLIETLSNAKVIGLNGGFET............................................................................................................................................................................................................................. 315
8 -6.280[R] COG5271 AAA ATPase containing von Willebrand factor type A (vWA) domain  ali follow..  11  118.....................................................................GNVFFNSHVPLPCSLVLTKSTQENLNRITPYLVQKRPILLAGPEGI-GKKFLITQIAAKL-----------------GQQIIRIHLSDSTDPKML-IGTYTSPK-VLTQAVITGKWILFTNIEHAPSEVLSVLLPLLEKRQLVIPSRGEGSFQMFATSSMKTKILGQRLWQILDLTYQPDECVEVVSTLYPVLSIICPTLYSVYKDIFDLFSQRSFLATSKIYRRLCLRDFYKFIKRVAFLYHKFMIPSDHVVISQELQDAVFKEAIDMFGAFIPSRDGFDLVVRNVAIELNIPPEKALQLRYSIPVFQNLEHNINIGRCSLKKLSTIRSCSTNSYAFTSSSLGLLEQLAAGVQTNEPLLLVGETGTGKTTTIQLLAGLLGQ 493
9 -5.550[I] KOG0693 Myo-inositol-1-phosphate synthase  ali follow..  10  7..............................STLEVISPKVQVDDEFITTD------YDYQTSHVKRTADGQL-------------QVHPQTTSLKIRTGRHVPKLGVMLVGWGGNNGSTLTAALEANRRQLKWRK-RTGVQEANWYGTQASTVFIGSDEDGGDVYVPMKELLPMVEPDNIIVDGWDILQDQIYDQLAQLRPRPSIYDRADNVIRGTRLEQYEQIRKD---IRDFRERSGVDSVIVLWTANTERFADVQPGLNTTSQELIASLEANHSEVSPSTIFAMAS----------IAEGCTYI----------------------NGSPQN--TFVPGLIQLAEEKNVFIAGDDFKSG--QTKIKSVLVDFLVGAGIKPVSIASYGNNDGKNLSAPQQFRSKEISKSNVVDDMV................................. 368
10 -5.280[T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases  ali follow..  12  29......................SSSELDFVSRFKTGELAVESGSLYTVLHG---DGRRQILNYVMPGDLVGLQGTVMGEMEHSVEALSPVTLCVFERSRLNNLFTDHPTLAFD-SIGRRTAIERAAYLIAFLYRKAKAANLLPGETPIPVTQQHVAD--------LGLSIVHTNKTLRKLVDRGL-IRWIDKGCLVLDEAGLSHVAGWESDEKR............................................................................................................................................................................................................................................. 245
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.