Scheduled maintenance will begin on May 30th, 2025. Server will be temporarily unavailable — learn more.
current user: public
If you have questions about the server, please let us know.

Query: [J] COG1096 Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain), from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .
# Score Template Links and tools%idFirst MEEGEERKKTIKNGDFVLPGDYLGVIEEYLPGEGVIVEDGNLYSARAGWVKINKDKVEISLEPASSVPPIPKKGDIVYARVIDVKQQAVLLRMIKIEGQENREIATSKLAGIHISQVKDGFVEDLRNEFKIGDIVRARVIADEKSPIQLTTKDPDLGVVYALCSKCRTPLVRKGNQLVCPRCGNVETRKISTLYRKVKLLast
1 -97.400[J] COG1096 Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain)  ali  100  1MEEGEERKKTIKNGDFVLPGDYLGVIEEYLPGEGVIVEDGNLYSARAGWVKINKDKVEISLEPASSVPPIPKKGDIVYARVIDVKQQAVLLRMIKIEGQENREIATSKLAGIHISQVKDGFVEDLRNEFKIGDIVRARVIADEKSPIQLTTKDPDLGVVYALCSKCRTPLVRKGNQLVCPRCGNVETRKISTLYRKVKL 199
2 -77.700[J] KOG3409 Exosomal 3`-5` exoribonuclease complex, subunit ski4 (Csl4)  ali follow..  23  2.......SEQQDETVVCLPGERLCRTEDIVLGIGTYEQNGYIYASKSGIVNIEDSGQVVSVHKPGFHLTIPATGDVVTARVLVTTPKFAKCAIFCVRNVLLESSYRGLLRKEDVRETEKDRV-DIYKSFRPGDVILARVINQLEQSFLLTTAENELGVVIAYASDYRKMVPVGWSEMQCPQTTIKEPRKVAKVLPESSI 200
3 -55.700[A] KOG3013 Exosomal 3`-5` exoribonuclease complex, subunit Rrp4  ali follow..  17  42GEDVLEEFDKSIHQNLVTPGQLVTDDPQFMRGHGTYFEDGGIYASVAGSVQRVNKLISV---KPLRSKYVPEIGDLIIGKIAEVQPKRWKVDIGAKQNAVLMLSSINLPGGIQRRKLETDEL-QMRSFFQEGDLLVAEVQQYFSDSVSIHTRSLKYGKLRNGVFLKVPPVVRSKSHAYALAGG................ 223
4 -43.900[J] COG1097 RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain)  ali follow..  18  1...........MDKKIVIPGDLLSE-NQKKAGYGTYVKNDKIYSSLCGIENLKEDKVGVI---PLAGAYIPSANDVVIGIVIVVTPSNWIFDIAAPYDGLLHVSEYPR----------RVESREMPEILNVGDSVILRVKDVDSMKVELALRDPSLGQIIKVESVKVPRVIGHGGSMISMLKKETNCSIFVGQNGRIWI 180
5 -35.800[J] KOG1004 Exosomal 3`-5` exoribonuclease complex subunit Rrp40  ali follow..  13  2.....AEVEEKGLLSYYFPGERIPQDGSIRLGPGLVDREEEIVVSKAGRLHQTGKN--AMLIDSRTKRYIPATNDQVIGQIISRFAEGYRVDIGSAHIAQLNALAF------------ENVTRKSRPNLNVGSLVYARVSLADRMEPELECFDATTYMITGLSLSHCRKLILPKNTLLQTLGSYIPFEIAVGMNGRVWV 203
6 -16.000[J] COG1093 Translation initiation factor 2, alpha subunit (eIF-2alpha)  ali follow..  24  7......................................................................PEVGDLVVVKITEVKNFGANGIL---------EEYPGVEGYIHISEVATGWVKHIRSYLREGQRVVCKVINVNQERKNVDLSLKRV........................................... 83
7 -14.600[J] KOG2916 Translation initiation factor 2, alpha subunit (eIF-2alpha)  ali follow..  14  14......................................................................PEVEDVVMVNVRSIAEMGAYVSL---------LEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRV........................................... 90
8 -13.800[J] COG1098 Predicted RNA binding protein (contains ribosomal protein S1 domain)  ali follow..  25  4.......................................................................EVGSKLQGKITGITNFGAFVELPG-----------GSTGLVHISEVADNYVKDINDHLKVGDQVEVKVINVEDGKIGLSIKK.............................................. 75
9 -12.700[K] COG1095 DNA-directed RNA polymerase, subunit E`  ali follow..  16  22YDVAVREVTKRSLEGRLV--DVINEKTSQNEGKYLVISVLYTESIGEGTI-VHGDGGVYQEVKYRALVYYPEMQEIVDGEVVSVQKFGAFIKFSSFEGLLHISQIMDDRIDIDLENKR----KETKRDLKVGDRVRVRIVAMN-SKIGFTMKQVGLGKL........................................ 183
10 -11.500[K] KOG3298 DNA-directed RNA polymerase subunit E`  ali follow..  15  33....................ADVEGTCSGQYGYIICVLDSNTIDIDKGRVVPGQGFAEFE-VKYRAVLWRPFRGEVVDAIVTTVNKMGFFANIGPLNVFVSSHLVPPDMKFDPTANP-----SGEDQVIEKGSNVRLKIVGTRTDATEITMKEDYLGVL........................................ 172
11 -10.500[K] KOG3297 DNA-directed RNA polymerase subunit E`  ali follow..  12  22TISAITHQLNNKFANKIIPGLCITIYDLLTVEEGQLKPGD-------GSSYINVTFRAVV--------FKPFLGEIVTGWISKCTAEGIKVSLLGIFDDIFNMLFEGCYYTPEESAWIWPMDEETKLYFDVNEKIRFRIEREVAYALLGSCQTDGMGLV........................................ 208
12 -9.030[J] COG0539 Ribosomal protein S1  ali follow..  12  390................LVHLSDISWNVPGEEAVREFKKGDEISAVVL-AVDAERERISLGIKQMENDPFN-KKGALVNGTVTAVDAKGATIELED-----------GVEGYIRASEVSRDRIEDASLILNVGDKVEAKFTGVDRKNRVINLSIKAK........................................... 522
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 7   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.