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Query: [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB), from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MASVVTITLNAAYDLVGRLNRIQLGEVNTVETLGLFPAGKGINVAKVLKDLGVNVAVGGFLGKDNSADFEQMFNQHGLEDKFHRVDGKTRINVKITETEADVTDLNFLGYQISPQVWQQFVTDSLAYCLNYDIVAVCGSLPRGVSPELFADWLNQLHQAGVKVVLDSSNAALTAGLKAKPWLVKPNHRELEAWVGHPLNSLEEIIAAAQQLKAEGIENVIISMGAKGSLWINNEGVLKAEPAQCENVVSTVGAGDSMVAGLIYGFEKGLSKTETLAFATAVSAFAVSQSNVGVSDLSLLDPILEKVQITMIEGLast
1 -94.300[G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)  ali  100  1MASVVTITLNAAYDLVGRLNRIQLGEVNTVETLGLFPAGKGINVAKVLKDLGVNVAVGGFLGKDNSADFEQMFNQHGLEDKFHRVDGKTRINVKITETEADVTDLNFLGYQISPQVWQQFVTDSLAYCLNYDIVAVCGSLPRGVSPELFADWLNQLHQAGVKVVLDSSNAALTAGLKAKPWLVKPNHRELEAWVGHPLNSLEEIIAAAQQLKAEGIENVIISMGAKGSLWINNEGVLKAEPAQCENVVSTVGAGDSMVAGLIYGFEKGLSKTETLAFATAVSAFAVSQSNVGVSDLSLLDPILEKVQITMIEG 313
2 -36.900[G] COG0524 Sugar kinases, ribokinase family  ali follow..  21  1MMSVFIL--SYAKALVMTTDRILAGETLIGYDFRQTWGGKGSDMAVQAVRLGAEVAYAGVVGDDTGHEFVGLMQEEGVNIDALTISGELPTGAGLIDKEARNVIVVDMG--ANKLFTPALVDSALSQLKQSNVVLTQLEIP----LETARYGLQRAKEFGKITILNAPARDLRGLDLSAIDYLTPNETEARVALGLPPDDPRSNREIANLLLETGCQYVVMTLGESGSAVFGRNDTQEIPPCII-DVVDSNGAGDSFNAALAVALDEGLPISEAVLFANATAALCCMDWETSYRYREDVDAFMRSITVKE... 309
3 -30.800[G] KOG2854 Possible pfkB family carbohydrate kinase  ali follow..  13  15.........NPLLDVSAVVDQ-MYDEMSQKFNVEYIAGGATQNVAQWMLQVPGATSYMGSIGKDKGEAMKKDATAAGVYVHYYEDEATPTGTCGVCVLGGERSLIANLSAA-NCYKVEHLKKPENWALVEKAKFYYIAGFFLTVSPESIQLVREHAAANNKVFTMNLSAPFICEKCLPYMDYIFGNETEARTFSRVHGWETDDVEQIAIKMSQTYKRTTVITQGADPVVVAEDGKVKKYPVIPLEKLVDTNGAGDAFVGGFLSQLVHGKGIEECVRAGCYASNVVIQRSGCTYPEKPDFN............. 344
4 -28.300[G] KOG2855 Ribokinase  ali follow..  17  8KGLIVSF--EMLIDFVPTVSGVSLSESPGFLK---APGGAPANVAIAVSRLGGRAAFVGKLGDDDGHMLAGILRKNGVDDQGINFDEGARTALAFVTLRSDGER-PSADMLLRPDELNL------ELIRSAKVFHYGSSLITEPCRSAHMKAMEVAKEAGALLSYDPN-RTQIMSIWDKADIIKVSDVELEFLTENK----TMDDKTAMSLWHPNLKLLLVTLGEKGCTYFTKKFHGSVETFHV-DAVDTTGAGDSFVGALLQQIVDDARLRKVLRFANACGAITTTKKGAALPTDIEALSFLKD........ 325
5 -25.000[M] COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase  ali follow..  17  13....VLVLGDVMLDRYWATNRISPEAVVRVQENEERAGGAA-NVAMNIASLNVPVQLMGLIGQDTGSALSLLLEKQKIDCNFVALETHTITKLRILSRHQQLLRLDFEED-FNNVDCKDLLAKLESAVKNYGALILS-DYGKGT-LKDVQKMIQIARKANVPVLIDPKGTDFER---RGATLLTPNMSEFEAVVGKCNTEEEIIEKGLKLISDIELTALLVTRSEKGMTLLRPNQEPYHLPTVAKEVFDVTGAGDTVISVLATALADGRSFEESCYLANVAAGIVVGKLGTSTVSTVELENAIHA........ 314
6 -17.500[R] KOG3009 Predicted carbohydrate kinase, contains PfkB domain  ali follow..  18  335....VVSIGATIVDFEAITSEVKDDGGSYNGQVVQRMGGVARNHADALARLGCDSVFISAIGDDNGHFFRQNSHKIVESNE--------------------------------------------DALESSDFILLDSNLSV----PVMARVLEIAKKHDKQVWLEPTDKVFDTGLVGAVTAASPNANEFLKWAKLCHVSVDELIEKEKTKLLLNTSIFIVTLANKGSAVVYRNKLSLPPPLQMNKVVSVSGAGDSFNSGVIAGLAHNKTVVESLQIGQECARLTLQTSLA...................... 597
7 -17.300[H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase  ali follow..  17  8...................................NDKSRALQ-ADIVA-----VQSQVVYGSVGNSIAVPAIKQNGLNVFAVP-------TVLLSNTPHYDT----YGGAIPDEWFSGYLRALQERDALRQLAVTTGYMGTASQIKILAEWLTAXRKDH-PVIGDIDSEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSAS-LVVVVTADSVNVISHSRVKT--DLKGTGDLFCAQLISGLLKGKALNDAVHRAGLRVLEVMRY......................... 266
8 -13.500[H] COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase  ali follow..  21  17....................................GGGAGIQADKTFQMRG--------------------------------VFGTCVITAVTAQNTLGVSAVHLVPTETITAQIQAIREDFD--------AYKIGMLGTAEIIECVADKLKMIAKGGAPLLQDSAVAALTRLLLPDTDVLTPNLPEAEALTGVHIENRKDAERAAKILLDYGVKNVVIKGGGRCTDWLFTQNETLELDSPRFPTAHTHGTGCTFSACITAELAKGLDVCKAVRTAKSYITAAISS......................... 250
9 -13.000[H] KOG2599 Pyridoxal/pyridoxine/pyridoxamine kinase  ali follow..  12  9.........................................IGNKRVLS---QSSVSHGYVGNRSATFPLQLHEWEVDVVPTVHFSNHLGYGAT-------------RGSACIPEEVHDLLNALLQDNGIVYDAILTGFVPNHDIIQVIFDCVLAYKKDKVLWLLDDQGKMYYKAMIPHAFAITPNAFEVEILTDIVIHTQMDAKRGLEKIYQLGIQNAIITSFEVESCEHGKPQLFLYQFPSLSG--VFTGTGDLFSGLLLAKYREELDKRKHQQSDETKQTKRPTVLACAV.................... 269
10 -12.200[HK] KOG2598 Phosphomethylpyrimidine kinase  ali follow..  15  45LPTVMSIA---GSD---------------------SSGGAGVEADKTITAHR--------------------------------CYAMTCVTTLTAQTPVKVYGAHNIPKKMVSQILDANLQDMK--------VIKTGMLTVDAIEVLHEKLLQL-GENRPKLVIDASDSLIIEKISPFADILTPNISDCFMLLGEEVSKLQDVLEIAKDLSRINCSNILVKGGITDVLYLGAEQKFITFKGQFVNTTRTHGAGCTLASAIASNLARGYSLSQSVYGGIEYVQNAIAI......................... 298
11 -10.100[G] COG0063 Predicted sugar kinase  ali follow..  14  51.....................................GGGPYSGAPALAALAALRAGADLVTVAVPESVAGIVASYSPDLIVRKLFSSV---------------------------CPEDLSILPDLINSHDVVVMGMGLGRATET---LETVRKLLPFCRKAVLDADALAALSG-GNCEIIVTPHAGEFARLRDMETPDSPETREKAVREFAAEKGVVTLLKGKVDIISDGKQTLLNRTGNP----MTVGGTGD-VLAGITGSLFSRNPAFLAAACAAAAGDLAFEKAGNALLATDVIGKISEIIK...... 297
12 -9.550[G] KOG3974 Predicted sugar kinase  ali follow..  14  23.........................................................MGVIGGSLEYTGAPYFAASSASRLGADL-------IHIFCDPDAAQVIKGYSPDLIVHPGMTANSIIPKLSRMDAIVIGPGLGRNPNIWPLMQELFEFVRNRDVPFVIDGDGLWFVSE-QMSATVLTPNIVEFSRLCKSALGEEDQLQHLAAELSRK-MNVTIYLKGEVDLVVTPNGEVSKCST---SSLRRCGGQGD-VTAGSLGLFLWTSAHHEAGIASSTAGRRAFEKHGRSMNTPLLLDEIPKLVR...... 289
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 9 3 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;