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Query: [E] COG1280 Putative threonine efflux protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNTALLGLFIPTFFFVSITPGMNMTLALTLGMSVGYRRTLWMMVGELLGVALVAVSAVVGIAAVMLRYPDIFTLFKIVGASYLVYLGVQMWRSRGKLAINIEQENTYQGSDWGLLVQGFVTAIANPKGWAFMVSLLPPFIDQSLSLAPQLTVLVAIILLSEFISMSLYATGGKGLKRLLSQAHHVRLLNRIAGSLMAGVGIWLYFSLast
1 -93.600[E] COG1280 Putative threonine efflux protein  ali  100  1MNTALLGLFIPTFFFVSITPGMNMTLALTLGMSVGYRRTLWMMVGELLGVALVAVSAVVGIAAVMLRYPDIFTLFKIVGASYLVYLGVQMWRSRGKLAINIEQENTYQGSDWGLLVQGFVTAIANPKGWAFMVSLLPPFIDQSLSLAPQLTVLVAIILLSEFISMSLYATGGKGLKRLLSQAHHVRLLNRIAGSLMAGVGIWLYFS 206
2 -64.900[R] COG1279 Lysine efflux permease  ali follow..  12  2..FSYYFQGLALGAAMILPLGPQNAFVMNQGI--RRQYHIMIALLCAISDLVLICAGIFGGSALLMQSPWLLALVTWGGVVFLLWYGFGAFKTAMSSNIELASAEVLKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDV--EPKRWFALGTISASFLWFFGLAILAAWLAPRLRTAKSQRIINLVVGCVMWFIALQLARD 201
3 -12.600[S] KOG2881 Predicted membrane protein  ali follow..  15  68.......GFLASFSVIVVSELGDKTWFIAVIMSMRHSR-LTVFSGAMGALALMTVLSAC-LGWITQVIPRAV--TYYLSTALFALFGLKMLHEGWTMSPNEGQEGYEEAQAEVA-TRKIFLFTSRIFIEAFSLTFVAEWGDRSQLTTIILGARENIAGVIGILGHALCTGIAVIGGKIVAQRISVRTVTLIGGVVFLLFALSALFI 288
4 -11.500[O] COG0785 Cytochrome c biogenesis protein  ali follow..  12  1MDVGLVTAFL-GGTLALLSP-PAFFASSVGAGPRMILHGVVFYAGLL------VLLVPLGLGILGELFITQRQTIIVVSSIVLIILGFVQIGKALPGLDRLQSKATVTSGLGKSFLLGMTSSIAGFCSGPILGAVL--TLAATSGNSITSALILSAYGAGMVLPLMAIAALWAKLGQRGQQGRQWHIVSVISGALIIAVGILFWST 221
5 -11.100[U] COG2095 Multiple antibiotic transporter  ali follow..  11  1MQSFEIAIFLQFFLGLVAAVNPVGIMPVFVSLTGHMEKNKTAATANIAVAIILIIALLAG-QMLLDLFSISLDSFRVAGGLLLLSIAFSMMSGKLGEDKQNKQEKSEYISREQIAVVPLAMPLMGPGAISSTIVY-------GSRYPNMLDTLGIILTVVAFSFCSWLLFRSAPYIVRLLGQTGINVITRIMGLILGALGIEFIAN 202
6 -10.200[P] COG4300 Predicted permease, cadmium resistance protein  ali follow..  10  3...CFMIQNVVTSIILYSGTAVDLLIILM-AKRKSRKDIINIYLGQFLGSVSLILLSLLFAFVLDYIPSKEI--LGLLGLI--ILLGIKVLLLGDSDGEAIAKEGLRKDNKNLIFLVAMITFASC------IGVFVPYFTTLNLA---NLIVALLTFLVMIYLLVFSAQKLAQV----SVGETLEKYSRWFVAVVYLGLGIYILVE 196
7 -9.910[S] COG2119 Predicted membrane protein  ali follow..  12  19.......VLAISITTVALAEIGDKTQLLSLLLASRYRKPIPIIAAIFLATLANHALAAWLGVVVADYLSP--DILKWVLVVSFLAMAGWILIPDKLDGEESISTRGPFVASFIA----FFMAEIGDKTQIATSIL-----------GAQYADALSWVIVGTTLGMLLANVPVVLIGKLSADKMPLGLIRKVTAGLFLLMALATAF. 199
8 -9.590[OC] COG4232 Thiol:disulfide interchange protein  ali follow..  16  166....SALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIMALTYTALGLVVAAAGLQFQAALVLIGLAIVFTLLAMSMF-SSLQTRLTLMSNRQQGGSPGGVFVMGAIAGLISPCTTAPLSAIL--YIAQSGNMWLGGGTLYLYALGMGLPLMLITVFGNRLL----KSGPWMEQVKTAFGFVILALPVFLL.. 377
9 -9.260[R] COG2215 ABC-type uncharacterized transport system, permease component  ali follow..  9  81....LIGLSFTYGVFHAAGPGHGKAVISSTELKRGVLLSFLSSILQGVVAILLIGAVYLVLRGSSISMTNATRALEIASYALIAAFGGWLVFRKHAHAPDPALLKGDRFALSEAWSAIVAVGLR-P-IVLSFALLNGLYLGGVLSVFAMSIGTAITVSILATMAVTAKGIAVRYASSDSAAARISNGIEIAGALLVLLLGLVLLGA 340
10 -7.990[P] COG0672 High-affinity Fe2+/Pb2+ permease  ali follow..  10  379.........FVYSLLIIVREGLEALLIVAAIVAYLVKNN-LIRQSVVVALIA-SVLTAFIFQWLFANSGQSRELLEMIAVVMLFSMSYWLLSKAEARNEGKFAKSLSSGSIIGLWLTSFLAVYRE-ETVLFYLALIGDANTTSGHLSVLAGFGVGCVILLVAYLVMRFTVVKLPLKPFF----------IFTGGFMYLMAFVFA.. 577
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Schwarzenbacher R, Godzik A, Jaroszewski L. The JCSG MR pipeline: optimized alignments, multiple models and parallel searches. Acta Crystallogr D Biol Crystallogr. 2008 Jan;64(Pt 1):133-40. Epub 2007 Dec 5.