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Query: [M] COG1361 S-layer domain, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKKAMALILGLILGSLVQPSLAQGPELLYEGYMNKGDYLLVGPLMILLKDVVYDINDGKWKGVFIVFNEDMEPIGPNLTLIYVPDPQKVRTLLQNQTFLRAMAETLGYNPDNPIEYAEFLRWLSTASQMEIWNAIVKTIDEHPELGIRLEDISKPYYVPNARPVGVNETIKIEYRGKTVYITVLSAYPNGVKVSISGPIQWRASMVQGLLLSKIDVKGTIKPGQYFTVEVHLKNIGSRKVRFVTAVLSPTPVVPSSTKFKTEEESLATTVPQVLTQTGTIQGTLYPVESSVKFIDLIEPGEDKVIKFLYKVNENAKPGDYPLYLTVIYFAYTTGENLEQRTLYDTAVVTVARDYEANFIIVQNVPRIVHPGEDFTINVTFKNMGEDPAKDVRGTLILEDITGRVFTPVSPSNFYRKFVDPGMEFNETFKLHVSESAKTGTYTFKIRLKYYSGNSNQEKTQDFTISTTVIRRREAFIEIDNVTLTPEKIEPGTTFNITLRLRNVGEGYAKGLEVRIVPTKALVRREIKKVDLSQLSNLPIPGGKELAKNLQTALNQVIGQIAQEEVSAFLPIGEDNVKYNGVIMPNQTIEIHFTLKANERLENNIYPIKIEIKYLSSPDDKLISDERIIGIDVTGSEKLVISSISTSPSRILPGTSNVEISFKIENVGDGKADYIIIMPNPQFPFKLSETSDQIINVGSLGKGDSAQASFKVDVDENAKSGRYLIPLTIEYKDPTGKFRQIEVNIPVIIAEKPKLVITDVRFGEKPVQGKDVNIYITVKNVGGEQAESVVIEGVVRSSQPFTLVKRTDYIGTLNPNQTGEGVITLSIEKDAVPKVYNILIRMRAVGDKEKGDDNVYVFEGTIKVPVKENTESKEKLRNLAIGAGILAIVITLLTYFKRRHLast
1 -222.000[M] COG1361 S-layer domain  ali  100  1MKKAMALILGLILGSLVQPSLAQGPELLYEGYMNKGDYLLVGPLMILLKDVVYDINDGKWKGVFIVFNEDMEPIGPNLTLIYVPDPQKVRTLLQNQTFLRAMAETLGYNPDNPIEYAEFLRWLSTASQMEIWNAIVKTIDEHPELGIRLEDISKPYYVPNARPVGVNETIKIEYRGKTVYITVLSAYPNGVKVSISGPIQWRASMVQGLLLSKIDVKGTIKPGQYFTVEVHLKNIGSRKVRFVTAVLSPTPVVPSSTKFKTEEESLATTVPQVLTQTGTIQGTLYPVESSVKFIDLIEPGEDKVIKFLYKVNENAKPGDYPLYLTVIYFAYTTGENLEQRTLYDTAVVTVARDYEANFIIVQNVPRIVHPGEDFTINVTFKNMGEDPAKDVRGTLILEDITGRVFTPVSPSNFYRKFVDPGMEFNETFKLHVSESAKTGTYTFKIRLKYYSGNSNQEKTQDFTISTTVIRRREAFIEIDNVTLTPEKIEPGTTFNITLRLRNVGEGYAKGLEVRIVPTKALVRREIKKVDLSQLSNLPIPGGKELAKNLQTALNQVIGQIAQEEVSAFLPIGEDNVKYNGVIMPNQTIEIHFTLKANERLENNIYPIKIEIKYLSSPDDKLISDERIIGIDVTGSEKLVISSISTSPSRILPGTSNVEISFKIENVGDGKADYIIIMPNPQFPFKLSETSDQIINVGSLGKGDSAQASFKVDVDENAKSGRYLIPLTIEYKDPTGKFRQIEVNIPVIIAEKPKLVITDVRFGEKPVQGKDVNIYITVKNVGGEQAESVVIEGVVRSSQPFTLVKRTDYIGTLNPNQTGEGVITLSIEKDAVPKVYNILIRMRAVGDKEKGDDNVYVFEGTIKVPVKENTESKEKLRNLAIGAGILAIVITLLTYFKRRH 899
2 -53.800[S] COG1470 Predicted membrane protein  ali follow..  12  1MNRYLLLLVLLLLTPSIKLSTAKEVNIIFKGRILPQERLIIG----------------NYTITV--------------------EFGIDNFPYVIVSNGTSKLVIERAEFGASITIENLSITIGSYNARKGLFIVASWSSEGEKHVAKVGRYFEGFEVITVTNSSVTLKRGITTKLILYGRYGIRYSNGTIFLYKLPSVEVKKKEERELVVFYPYSEVTTEVNRSIMLPLTIFNNGTET-VNVTFSVVNAPK----------------------------DVKFYYQGIEIKKL-KLREKESITLQLKV---LPSSAGSHVVKFSIN-----------GDIYSFYVNVVQPKMEALKIT-APILVQEAEAGSKVTFSVLLSAGEDSV---ISMDVREPRDWKACILVDGVRAQEI-YLRRGETKVVNLILEIPRNASLGYYESKISFTVRKSNGEVIKNETITLGVNI-----------------YKTYKGQKATLKLILVDDTGSPVPKALVKVG--------------------------------------------------------------------NESYATDSTGTLEVEMNPGKYVITIEKEGYETKKELGDGEKKELKLLLVREPYYFNVEAQSDIYPIVMEGLSRPFTIVIENLGKSDDEYKLEIRGIPENWNAFFTESAEGNIEKVKSGETKTVYLKVYPSLNAMPGTYNATITVI----SSSGIKKEIPVKIKLIGSYNMNVNLLNYRLTITAGEEKTAMMDIFNFGNAPLTNLKITVKGPQGWDVKVDPSQ--IPSLSPKGRERVTITVKVPEGTPAGDYRVQITVK---------ADQAEWQDTLRVVVRQRSTST-------IGVLILIISFALVLFMMRR. 724
3 -19.100[R] COG2373 Large extracellular alpha-helical protein  ali follow..  8  395..............DLYRP----GETVILNGLLRDADLDVIKPLYHFTWPLDSNAATGMWHIRANT---GDNQYRMWDFHVEDFMPERMALNLTGEKTPLTPKDEVKFSVVAPANGNTLQGQLFRPLREAVSALPGFEFGDIAAENLSRTLDEVQLTLDDKGRGEVSTESQWKETHSPLQVIFQGSLLESGGRPVTRRAEQAIWPADALP-DSTVKQPIVDEGSNAAFDIVYSDAQGVKKAVSGLQVRLIRE---DYYWNWSEDEGWQSQFDQKDLIENEQTLDLKADETGKVSFPVEWGA-----YRLEVKAPNEAVSSVRFWAGYSWQDNSDGSGAV---------------RPDRVTLKLDKASYRPGDTIKLHIAAPTAGKG-----------------YAMVESSEGPLWWQEIDVRAQGLDLTIPVDKTWNRHDLYLSTLV-VRPGDKSRSATPKRAVGVLHLPLGDENRRLDLALETPAKMRPNQPLTVKIKASTKNGEKPKQVNVLVSAVDSFFGQKRYGADIYDIYGQVIEGQGRLAALRFGGDGDELKRGGKPPVNHVNIV----VQQALPVTLNEQGEGSVTLPIGD---NGELRVMAQAWTADDFGSNESKVIVAAPVIAELN------------PRFMASGDTSRLTLDITNL-TDKPQKLNVALTASGLLELVSDSPAAV---ELAPGVRTTLFIPVRALPGYGDGEIQATISGLALPGET---VADQHKQWKIGVRPAFPAQTVNYGTALQPGETWAIPADGLQNFSPVTLEGQLLL--SGKPPLNIARYIKELKAYPYGQTASGLFPSLYTNAAQL................................................................... 1206
4 -16.800[U] KOG3317 Translocon-associated complex TRAP, beta subunit  ali follow..  12  50.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SEDETRARLLVSKQILNKYLVEKSDLLVRYTIFNVGSGAATKVRLVDSGFHPEAFDVVGGQPVVDRIAPQTNFTHVLVVRPK---AFGYFNFTAEVSYKAVEESETLQLAVSSEPGEGGIVNLNEYNKRFSSHFFDWVAFAVMTLPSLAINKKH 220
5 -13.900[W] KOG4802 Adhesion-type protein  ali follow..  8  189.......................................................................................................................................................................................................................................................................................................ELRFTELQSGQLEVKWSSKFNISIEPVIYVVQRRWNYGIHPSEDDATHWQTVAQTTDE--------RVQLTDIRPSRWYQFRVAAVNVGTRGFTAPSKHFRSSKDPS---APPAPANLRLANSTVNSDGSVTVTIVWDLPEEPDIPVHHYKVFWSWMVSSKSLVPTKKKRRKTTDGFQNSVILEK-------LQPDCDYVVELQAITYGQTRLKSAKVSLHFTSTHATNNKEQLVKTRKGGIQTQLPFQRRRPTRPL----------------------------EVGAPFYQDGQLQVKVYWKKTEDPTVNRYHVRWFPEACAHNRTTGSEASSGMTHENYIILQDLS---------SCKYKVTVQPIRPSHSKAEAVFFTTPPCSALKGKSHKPIG---GEAGHVLSKVLAKPENLSASFIVQDVNITGHFSWKMAKANLY-----------------------------QPMTGFQVTWAEVTTESRQNSLPNSIISQSQILPSDHYVLTVPNLRPSTL--YRLEVQVLTPGGEGPATIKTFRTPELPPSSAHRSHLKHRHPHHYK................................... 674
6 -13.500[S] COG1572 Uncharacterized conserved protein  ali follow..  11  8LNRFFLYFAGILIFFIYTPCLAT-----FEGTPE-QDEL-------------IEITSGTVKGGLYVDGGEGLKKTPYVQEFNVPGDVVTWARVYVGVWGGTEEKTGTLDLTINGEEFESLDLEGKNDKGDDEDQNPAIYCTGHGVYWIAYDVGTNI---STGPVTVEAQTEGDIDGRVYGIILAAVYEDKEGQSTKYWVE-SETLASTHDEGYADFSGKVDTDKYNTANLAVVYLCGTPGLDDSLYFNEEQLSDGENSNDIANSKS--------------------FDFKFFDVLDLLEEDDNELKFQ------------------------RDEEDYVHPVLAALTLGTGEEGTSDLIVSGLTVPLLYAGKDNTIKASIKNIGKDSAYGFQAALYADGEI---------STAPVSSLSSGKSKTIEFNWKP---AWDGEQALKVYVDYTNKKKETCEVNNWNSPFLAKVVDLTPPELEIDYPEDGARVDAGYLTVSGTIEDTNR----NLTVDVNGQNALISGESWSATIVVSAVDGENNTGRELIVVEGKESSTDSKESSQSDLTVSSKAENETEPVNQSILGSQTREYEKQAVLSPISEGIGFISAILFLRYRNRGKR...................................................................................................................................................................................................................................................................................... 570
7 -12.800[R] COG3291 FOG: PKD repeat  ali follow..  8  1MKSKTLFIVFTLIFLIGVPSTVSARDIIVGG--EAGDVIIIKP--------------GTYVENINVSKARLTIKPETNNVFIEPADSTKATIILSNVGITLTGFDIDGSVYVNNENGGIGVGSESSGIIISGN----KITGGTGIDVACCGDYNEITDNDILNCSTGIYVYDERYVPPISGNKINNCDVGIHVS-----GLYYDLENNEITNCGVGVIAGETGGASLIGNKIMYCSDCGLK-VLGSLETKGAYNNYFNNTVNVKFGDYEDTYTWNTSLTEGTNIFGGPYLGGNYWAKPDGTGFSQTAVDANGDGIADSAYAISEKNYDYLPLTAKYNSASPASDFTANVTSGTAPLVVLFTDTGSGV---GDTYDVSLTVTNAAGSSTVNKSNYISVTPPQAPVADFFSPEVNDLRDFGESIPINETVSFIDNSTGSPMSWL-----DFGDGATSTARNPEHAYS-----------------------ARG-GYTVNLTVTNSGSNTTSKYGYVLVGVIDAPAIPAYFSSDVRSGNAPLTVTFVDDLDAES--------------------PNYPIWREWDFGDGVVQTYMVDDNDSATKKPGKYTVTLYMD--NRGGNSIITKYHYITVTDPNATVVNFS------ANVSSGPAPLVVLFTDTSTGPAPSS-------------------------DFGDGINSKHAMN--THTFTEPGNYTVSLTVE--NSAGNNTVTKTDYIVVTDPVATSSSGGSSHKSTKNATCVVYVGFDAKRTGKTTTIVEQLKNSSSLVSELPEGEVNIWVGSGETSSSKNIENPVIG---KVEKAWIQDKGID----QASISLNRYKDEKWEQFPASLSGEDDKFLYFTAETPGFSSFAITGE....... 891
8 -11.600[S] COG4885 Uncharacterized protein conserved in archaea  ali follow..  12  26........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KFESYARFGDIDMKLEAVNDSHAVVTFVT---EVRKENVEEFAIKAKIYDIQTDLLLNELEETFKSPESRFTAELTIPFE-----KTRDYKIVLYLQVGDRIYDSYRLTLRNLRNLVMKLEASLVDSDFLLTSVKNGSVGFVARFYVESVKD-YDVVARIKVLQADSNVLVGESWKNVTLQKGKTNIVSAEFEVPDD---YNYVVKLDVKKLSKGEVEKEVDFEAEKFVTAVEPEYVPKSGGVPGFEVVFALMALAGVALWRKARR. 301
9 -11.400[S] COG4719 Uncharacterized protein conserved in bacteria  ali follow..  9  1..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MFPG-GTTVKTHLTLTALALTSVSFAAQAAPAATSPIKLSGATYSVAQVTENGKTTERLVDASGKGALPGSLLQMTQKVQNVSARSVNGLRLNMRVDPATIYQSATCD--LPSLAASQTVNCNLRVRVK........................................................................ 176
10 -9.940[R] KOG3515 Predicted transmembrane protein of the immunoglobulin family of cell adhesion molecules  ali follow..  8  1...............MEGQIIPAGSVQKLLCVSSGGN-----PLATL-----------TW-------YKNDKRINSVIRAADKSVSAEITILANVSDNQAQYRCEASNSATEIPLFQSTTLSVHFAPETVKIRIEPEELRPGMEATISSNPPAKLSWWKDGIPIEAIWQLEACPSQFAMDLPAPPVHFAGARFHDNIRFACQSLKLRPFFLRTHSYLIPLPCPIRILCPCPPTGTPDMPQP----------------------------------------------GINNTSKPGLWGGTVSTLEFRVNVTQEMNGQVYTCQSA-----------NEALQRSAHEAVSLDVLYRPKFVPPPSSTAVGVEGESLQVSLQTR--ANPTPVTYK---TTIPQDGDHRIFADGGSLNFTRLHRDDAGI--YSCSASNSQGGATLNITVVVEYVSENIVVNPGEDAMLSCTVEGKPLTEEHVKTSYLHIKDAKREDVGNFRCVADNRDNPTNRDILLIVKFAPEIAKTPTLL-------RAASGTGERGRLPCRAQGSPKPQFIWRQDKKDLPINRTYKYEVEERKIDSLTYESTLIVDKVAPADYGAYECVAR----NELGEAVETVRLEITSQPDPPLSLNILNVTHDTVTLADGGLKASYRVRYRMADREQYKYIDGL-----------PNSHKLTIGGLRMNTL--YLFSVMSWNELGQSSYLPDLARAETKEAPPPSHPPTTSQTPLGGTSGMLLVGVGAGIVVVLVFVIGCCLHKRNEKRLKRVKKGYS----------SQTSSIDIRAL....................................................................................... 729
11 -9.930[S] KOG3594 FOG: Cadherin repeats  ali follow..  8  1..................................................................................................................................................................................................................MGNSSGWRGPAGQRRMLFLFLLSLLDQVLSEPIRYAIPEELDRGSLVGNLAKDLGFGVGDLPTRNLRVIAEKKFFTVSPENGNLLVSDR-CGKKSTCVLEFEMVAEKPLNFFHVTVLIQDINDNPPT----SQNITELEISELALTGATFALESAQDPDVGVNSLQQYYLSPDPHFSL----------IQKENLDGSRYPELVLKAPLDREEQPHHHLVLTAVDGGEPSSCTTQIRVIVADANDNPPVFTQDMYRVNVAENLPAGSSVLKVMAIDMDE--GINAEIIYAFINIGKEVRQLFKLD--------------------------------------------------------SKTGELTTIGELDFEERDSYTIGVEADGGHHTAYCKVQIDISDENDNAPEITLASESQHIQEDAELGTAVALIKTHDLDS---GFNGEILCQLKGNDREQIPEYNVTITATDKGNPPLSSSKTITLHILDVNDNVQASYTVHVAENNPPGASIAHVRVSYYIVASDLEPRELSSYVSVSARSGVVFAQRAFDHEQLR--AFELTLQARDQGSPTLSAVLVDDRNDNAPLVLGPEGSALFDMVPRSAEPGYLVTKVVAVDADSGYNALSYHIVQASEPGLFSLGLRTGEVRTARTLGDREAARQRLLVTVRDGGQQPLSATVMLHLI... 663
12 -9.730[M] COG4932 Predicted outer membrane protein  ali follow..  11  807............................................LEFGNLDTNRVF--KYKTKPKDNWFFSQWVNNKAIVSDNGADEQIYETKEFAFLQNEVIKVAGNIDSTFGNKVNWNMELLNIPERTLSNPVITNRLEQGNTGAQFIKNSFQVINTKTNEPINEENYDITFEGNTFTIQFKNYTAMAPKVNYSTISLLSGPISNETTVEAEDFSNVPMFFKKRNVAVSPVGTGSGIATIGTIKITKVDEDDTTKKLEGAKFQLYTLDGEKSGQEITTN------SEGEILLDGIQSGK-------YKLVETKAPEGYNIS---EYKEGKEITVSSSGEELLLTIKNAMKKGNVILTKKDSASHEVLADAEFELQ---NATGSKLKEKLTTD--------------ASGNIEITDLAPGDYKLIETKAPTGYQLDATPVNFTIDFNQSEAAKVSKTNTAKTGTVMLTKKDSAELRNEDETLVRENLVTDDNGEISVADLAPGDYKLIETKAPTGYQLDATPVNFTIDFNQSEVEKVSKTNTAKTGTVVLTKKDSATNAELADAT-FELRNESDTLVRENLVTDDNGEISV-----ADLAPGDYKLI---ETKAPAGYQLDATPVNFTIDFNQSEAAKVSKINTAKTGTV-------VLTKKDSATNAELADATFELRNESD-NLVTDDNGEISVADLAPGD-------YKLIETKAPTGYQLD-------------ATPVNFTIDFNQSEAAKVTKTNKK------KIGTIIVNFIDVDGNQLNDKEVHTGNVGEEY-KEIVGHTLVKDPANKKGMYKETSQEITFVYEKKAMPITVEPTEPSKPTEQLTESATVAEPKPIKQNIKTTNKSPNNKRKL-TGLFVSVAGVFFLRKPKQ 1620
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Li W, Godzik A. In search for more accurate alignments in the twilight zone. Protein Sci. 2002 Jul;11(7):1702-13.