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Query: [R] COG1579 Zn-ribbon protein, possibly nucleic acid-binding, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MHDALLSILAIQELDIKMIRLMRVKKEHQKELAKVQSLKSDIRRKVQEKELEMENLKTQIRDGENRIQEISEQINKLENQQAAVKKMDEFNALTQEMTTANKERRSLEHQLSDLMDKQAGGEDLIVSLKESLASTENSSSVIEKEIFESIKKINEEGKALLEQRTELKHATNPELLSIYERLLNNKKDRVVVPIENRVCSGCHIVLTPQHENLVRKKDRLIFCEHCSRILYWQESQVNAQENSTAKRRRRRAAVLast
1 -75.400[R] COG1579 Zn-ribbon protein, possibly nucleic acid-binding  ali  100  1MHDALLSILAIQELDIKMIRLMRVKKEHQKELAKVQSLKSDIRRKVQEKELEMENLKTQIRDGENRIQEISEQINKLENQQAAVKKMDEFNALTQEMTTANKERRSLEHQLSDLMDKQAGGEDLIVSLKESLASTENSSSVIEKEIFESIKKINEEGKALLEQRTELKHATNPELLSIYERLLNNKKDRVVVPIENRVCSGCHIVLTPQHENLVRKKDRLIFCEHCSRILYWQESQVNAQENSTAKRRRRRAAV 254
2 -15.400[S] COG4372 Uncharacterized protein conserved in bacteria with the myosin-like domain  ali follow..  13  84.........QLRVAKTELEQASQAKEEIESELTAVREEQQLVQERSRELNRNYTKALQLLRRVSEQSRNLRQEVANLSAERAQ--LNEQKDSLLAESSELQSQVKLRDQELSKRQERIAQQEKVLARQREQVQSLEKRFASLEAQRQQLQAEINQRDTKIDQLDQAIAAK.................................................................................... 242
3 -15.300[U] KOG0946 ER-Golgi vesicle-tethering protein p115  ali follow..  10  790LKQELATL-QLNSQSVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKE--QLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLADQDQKILSLKNKLKDLGHPVEEEDELESGDQEDEDDESEDPGKDLDH................................................................................. 961
4 -13.900[U] KOG4809 Rab6 GTPase-interacting protein involved in endosome-to-TGN transport  ali follow..  13  474.........HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQK--KIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSL................................................................................. 635
5 -12.800[S] COG3883 Uncharacterized protein conserved in bacteria  ali follow..  14  32.........DIQNQDKKINDIKSKKTGLQSDLSSLVADLEKAQEKAKSLQGEFDQTGKELKQLNQDIKDINERIKERETVLKEILDAENLSDLVGRVSAVNQLVDSDKSILEDQEKALKTKQTAVKKKQEEQATAIHEFEAQQNKIEAQKAEKEAIVAQLAADQAS........................................................................................ 208
6 -12.100[Z] KOG1003 Actin filament-coating protein tropomyosin  ali follow..  12  1..........MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVI................................................................................. 171
7 -12.000[O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation  ali follow..  13  656.......IAEMETIGQAYEDMQTQNQHLLQQVAERDDYNIKLVSESVKTKHAYNTHLSEKQVMEKQLHQVNASVENFKARIAHNEEQSEAYKLIQEDRHLVISLETTKWEVADADKEFRWLKSAVSSSEKEYEQISRRTDDIKLELDDEEEELMELNKELEELGSESVEAAIVRLQEEVKNCKNRPKEVVIVKCYHLFCQQC---IQRSLEIRHRK------CPGCGT.......................... 887
8 -11.100[S] COG5280 Phage-related minor tail protein  ali follow..  10  1MAKKISGIT---AIGADTTGVTNGLKDIGKQSNSVNSELRDVERLLKLNPNNVELVAQKQQLLSKQVELTTKKLDGLKGAQADVDRQKSGDIGEEQYRAFQREVVATEGRLDHYKQSLKDVESSSGEAGNATKGLGGKFDELGQSVEDVGEAVKGGVLMEAAD........................................................................................... 162
9 -11.100[D] KOG4438 Centromere-associated protein NUF2  ali follow..  12  222.........RLNELKLLVVSLKEIQESLKTKIEKLKNYKEKMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKIQD-EKLASILKESLNLEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKINKKHEDVKQYKRTVIEDCNKVQEKRGAVYERVTT................................................................................. 393
10 -10.700[UR] KOG4677 Golgi integral membrane protein  ali follow..  10  216.....ELKLARQKAQDQKEKAVEECNMHKRKIVGLEEEIRAMVEQLRLAKFNLNENKKEFDEYKNKLTAKEKLVESLKSEQGIGSSDRPVHLLQAEVEEIRVERDLTKADLESAQLQVYTLRSDMEELEAQIRDLQSQLSDQKRTHLEEKQTWDSTIGLLNEKVECSRIENE.................................................................................. 386
11 -10.700[YU] KOG4460 Nuclear pore complex, Nup88/rNup84 component  ali follow..  13  559.EECLQLLSRATQVEQYILKQDLAKEEIQRRVKLLCDQKKKQLEDLSYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKLLSDSE-RDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSLPKPTIILSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVN.................................................................................. 740
12 -10.400[R] COG5415 Predicted integral membrane metal-binding protein  ali follow..  8  2FSALGKWVRGSRNDKDFVTKYTADLSQITSQIHQLDVALKKSQSILSQWQSNL--YAFYNNNRLRKLAKLR---AIHQKKLEKLKEETHYNATSSIIQRFSSGEDQNDDAMVLLDDELNAKYQELNNLKTELEKFKKESHVKGLKKEDSDAWFDKIISVLAGGNELDSTSSLSPFKKI-------------------ICPQCHWKCYRLASKPII-----FICPHCNHKIDEVKEREDAIEAKQPAQPSQSEK. 274
13 -10.200[S] COG5293 Uncharacterized protein conserved in bacteria  ali follow..  14  266.........RVNFLTSQIHEATNKNITDQKLLEFYQSSLKSIENRREFLGSEIKRLRRDLVSRENFIREKSNERAELLEVLKTHGALEEYTMLQEIYLDNVANLNEINKR----IEELKQFEEERSSLKIEKELLLQRARRDYGERNEQAERAIDLFRINSRF........................................................................................... 453
14 -10.000[A] KOG4394 RNase P subunit that is not also a subunit of RNase MRP, involved in pre-tRNA processing  ali follow..  11  1.................................................................................................................MGKKAHGGKMKPEIDENGTLLVPPPRTIANQDHFHRLNYLYQISAYQTRARQKARTDAHTPLARNYIKSMDLISKKTKTSLKRTICKKCHRLLWTPKKLEITSDGALSVMCGCGTV......................... 120
15 -9.960[J] COG2023 RNase P subunit RPR2  ali follow..  17  1...................................................................................................................................MVDIVKRRDWEKKEKKKIAIERIDTLFTLAERVARYSPDLAKRYVELALEIQKKAKVKIPRKWKRRYCKRCHTFLIPGVNARVRLRTKVITCLECGYI......................... 103
16 -9.940[R] KOG4398 Predicted coiled-coil protein  ali follow..  14  101...........................................ESLTEKQQRYINLQAGLKTFSTRYERLIGQHRSNEDRLMAIKAKRKLELLQQLISGTGQRLRVLGERRDELRRANAEKRKNLPKYPDKVKMLENYVLDRVEKIEKLRETHLGLLDSIKQAARRSIQQL................................................................................... 229
17 -9.920[D] COG4942 Membrane-bound metallopeptidase  ali follow..  13  47.........QLKSIQADIAAKERAVRQKQQQRASLLAQLKKQEEAISEATRKLRETQNTLNQLNKQIDEMNASIAKLEQQKAAQERNQARQETIAQLKQTREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALNERKKTLAGLESSIQQGQQQLSELRANESRLRNSIAR................................................................................. 250
18 -9.880[D] COG5185 Protein involved in chromosome segregation, interacts with SMC proteins  ali follow..  15  355..DSLKYQVENQDISSEFEKMVSEREQLDRNLNMIGSKISELRKEVFDTDLLIQASIDSLEKKVQKFNSLAYRINKVRPFINEVRRS-----ITLEFHEEQNKSLKLQEHVDTVNDLIAELQDELRGIESRLTSVLSECNMLRETASEEKNAFDAESDKLERELQQLKLSSHNSMLQLDQRIQSIN.................................................................... 566
19 -9.550[U] KOG3838 Mannose lectin ERGIC-53, involved in glycoprotein traffic  ali follow..  8  313...........SENQRELRQIWQGQSQIADHLRELSRKVDEIIGRQETTLSLVSRNAGQALPPPAAGGVPQQQLPVGA------VSRSDVDLLLTNQNMLLSSIREIRQLVGDINVRTDNIQTNQKHPTAQIQSTGYDVQTLIAEMRDGMNQVKQGITHVGQRLAASVTVVQLLLVFIYNVFKNRSEAQA................................................................ 508
20 -9.520[L] COG0419 ATPase involved in DNA repair  ali follow..  10  90LTKTFKNLSEAKPIFDEIELLDKRLSETKTELSDLQGDLQGLDIRKDEIQSELDTLYLRRANLEKEIRTIDRETEVLRIELPSSIAHHNLDEIYAEREKLLEKRGYLRKQIERTKLEETSFKKKIDDAVLANNEQKLKLTKLNFQVN-ELEQLEKDINKSSEDCDLQKKKLLE................................................................................. 274
21 -9.480[S] COG5283 Phage-related tail protein  ali follow..  10  1MADIMVDSVTTG-IDLNETKAVEAINRLKSAVKDSTREWQINEAQAKSAGDAVSASKYRYEGLSEAMEKQKAYIANLSEGMKTIAGEKAYQKYNAQLTTAERSLASMTGQLNRAKSAYEYQQTGIEDLNKSLSANDKLMQSQIDLYEKKMGAAKAEVSGLSTSYAKQTEIYRAQ--TELKRLEAAEGTSS................................................................ 196
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;