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Query: [C] COG1600 Uncharacterized Fe-S protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLWSIMSKPLDLNQLAQNIKQWGLELGFQQVGITDTDLRASEPALQAWLDKQYHGEMAWMARHGMMRARPHELLPGTLRVISVRMNYLPANAAFASTLKDPTLGYVSRYALGRDYHKLLRSRLKKLGEQIQQYCGSLNFRPFVDSAPILERPLAEKAGLGWTGKHSLILNREAGSFFFLGELLIDLPLPVDQPVEEGCGKCVACMTICPTGAIVEPYTVDARRCISYLTIELEGAIPEAFRPLIGNRIYGCDDCQLICPWNRYSQLTDEADFSPRKALHNPDLLELFSWSEAQFLKVTEGSAIRRIGHLRWLRNVAVALGNAPWSNAVITALESRKGEHPLLDEHIEWAIAQQIEKRNACIIEVQLPKKQRLVRVIEKGLVRDALast
1 -136.000[C] COG1600 Uncharacterized Fe-S protein  ali  100  1MLWSIMSKPLDLNQLAQNIKQWGLELGFQQVGITDTDLRASEPALQAWLDKQYHGEMAWMARHGMMRARPHELLPGTLRVISVRMNYLPANAAFASTLKDPTLGYVSRYALGRDYHKLLRSRLKKLGEQIQQYCGSLNFRPFVDSAPILERPLAEKAGLGWTGKHSLILNREAGSFFFLGELLIDLPLPVDQPVEEGCGKCVACMTICPTGAIVEPYTVDARRCISYLTIELEGAIPEAFRPLIGNRIYGCDDCQLICPWNRYSQLTDEADFSPRKALHNPDLLELFSWSEAQFLKVTEGSAIRRIGHLRWLRNVAVALGNAPWSNAVITALESRKGEHPLLDEHIEWAIAQQIEKRNACIIEVQLPKKQRLVRVIEKGLVRDA 384
2 -19.100[C] COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB  ali follow..  36  114..................................................................................................................................................................................................ENNCIGCTKCIQACPVDAIVGAHTVMSDLCT------------------------GCNLCVDPCPTH........................................................................................................................... 160
3 -18.500[C] COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)  ali follow..  13  3.................................................................................................................KEIINVVHGTFTQLRSLVMIFGHAFRKRDTLQYPEEPVYLPPR----YRGR---------------------IVLTRDPDGEERCVACNLCAVACPVGCIPEFFRINFSRCI-------------------------CGLCEEACPTTAIQLTPDFEMGEFKRQDLVYEKHDLLISGPGKNPDYNYYRVAGMAIAGKPKGAAQNEAEPINVKSLLP....................................................... 182
4 -18.300[C] KOG3256 NADH:ubiquinone oxidoreductase, NDUFS8/23 kDa subunit  ali follow..  15  25...............................................................................LLAAQRAEPKDIVEVPKGYVYVNNKELSMEFADITDRAASTMFFGELLRGFAVTLAHIFKEPATINYPFEKGPLSP----RFRGEHA---------------------LRRYPSGEERCIACKLCEAICPAQAITTRYDIDMTKCI------------------------YCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLCNGDKWESEIASNLQADHLYR............................................................................ 217
5 -17.700[C] COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit  ali follow..  30  50..................................................................................................................................................................................................ESKCVKCYICWKFCPEPAIYGFVAIDYDYCK------------------------GCGICANECPTKAITMVREEK.................................................................................................................. 105
6 -17.400[C] COG1146 Ferredoxin  ali follow..  15  43..................................................................................................................................................................................................YDKCVTCGICFVTCGRRVFDVIVARPYNCMV------------------------ACQTCMNLCPTGA.......................................................................................................................... 93
7 -15.100[C] COG1142 Fe-S-cluster-containing hydrogenase components 2  ali follow..  22  37.......................................................................................................................................................................................LRVMLNEKESAPQLCHHCEDCAVVCPVNAITRV-QLNESLCV------------------------SCKLCGIACPFG........................................................................................................................... 95
8 -14.000[C] COG0348 Polyferredoxin  ali follow..  22  203............................................................................................................................................................................IGAAYGVIGAKGLFRIKVEH--RQQCDNCMDCYNVCPEPQVLESPLVLSKDCIS------------------------CGRCIDVCPEK........................................................................................................................... 274
9 -13.900[C] COG1145 Ferredoxin  ali follow..  25  286..................................................................................................................................................................................................TSRCIACGICMLRCPMKAIKEPASVDAEKCL------------------------GCGVCVPTCPMEAIELVERDELLELPDGMT--YVQELLADKGRDPSGLF...................................................................................... 368
10 -13.200[C] COG1150 Heterodisulfide reductase, subunit C  ali follow..  20  22..................................................................................................................................................................................LSELVEPVFEEEEVLSVQACYQCGTCTGSCPSGRRTS---YRTRLIMRKLQLGLVDEVIKS------DELWTCYTCYERCPRG........................................................................................................................... 98
11 -13.100[C] COG0437 Fe-S-cluster-containing hydrogenase components 1  ali follow..  32  63.................................................................................................................................................................................................LSISCNHCDDCTKVCPSGAMHKR-VVDEDVCI------------------------GCRYCHMACPYG........................................................................................................................... 112
12 -13.000[C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit  ali follow..  19  168...................................................................................................................................................................................................YECILCACCSTSCPSYWWNGDRYLGPAVLLQAYLIDSRDEATGERLDNLPFRLYRCHTCAQACPKG........................................................................................................................... 240
13 -12.800[C] KOG3049 Succinate dehydrogenase, Fe-S protein subunit  ali follow..  13  15............................................................................ATTLGGACLQASRGAQTAAATAPRIKKFAIYRWPHMQTYEVDLNKCGPMVLDALIKIKNEVDSTL----------TFRRSCREGICGSCAMNINYPLPHMYVIKDLVPDLSNFYAQYKSYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRIDSRDDFTEERLAKLPFSLYRC-NCTRTCP............................................................................................................................. 254
14 -12.300[C] COG2440 Ferredoxin-like protein  ali follow..  13  9...........................................................................................................................................................................RVEEKLYQNRYLVDPGRPHIKVRPHERPSANLLTHICPAKCYEGQVETTSDGCM------------------------ECGTCRVLCEASGEIV....................................................................................................................... 84
15 -11.800[C] COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit  ali follow..  19  275..................................................................................................................................................................................................SENCTMCNECAFVCPHAAILTNEEEMESAPEGFMTREMRGKDGLRYRIQVSMDCTGCNLCAETCPAKDKALVMKPFEEVAAKENPNWSFAINVKPKKNPGKK........................................................................................ 380
16 -11.600[R] COG2768 Uncharacterized Fe-S center protein  ali follow..  34  201..................................................................................................................................................................................................EEKCTKCDECVKICPSNAIEDY-QINREKCV------------------------KCLGCSEACDYGA.......................................................................................................................... 243
17 -10.300[C] COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain  ali follow..  199.............................................................................ADIGVSGCNFAVAETGSVCLVTNEGNLRLATSL--PKTHIAVMG-MERLAPTFKEVDVLITLLARSAVGARLTGYNTWLTG-----RLAGETDGPEEFHLVIVDNGRSKMLGSEFREVLRCIRCGACLNTCPAYRQIGGHGYGSIYPGPIGSVISPILGGYEEFKDLPSACSLCTACNQVCP-------------------VKIPLANLLLKHRRHIAESGMNPLAERLSVKAFTL----ANSHPSLWKIGMNVGAKVAK-PIQVGAIAEWTKARDLPDAEGESFRSWFKNR............... 467
18 -9.430[C] COG1035 Coenzyme F420-reducing hydrogenase, beta subunit  ali follow..  12  11..................................................................................................................................................................................................YDVCAACGACEAVCPIGAVT---GGGYQVCE------------------------GCLTCSRVCPVVDGFIQDELT-----------NVRKFFGARSKDNVGSQDGGVASGILKSLFKQGKIDCAVGITRNEKWEPEVVLLTSAEDVERTRGT----KYTSDPVLAALREAFEKYDRIA........... 165
19 -9.260[C] COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC  ali follow..  16  128.......RQRDKMALLDRIHQAGI-AGLGGAGFTASKLQGGLNGIITLIINAAECEPYITADDRLMQEHADEVITGIQVLIGIEDNKPEAIAALQRALRGQDDIHLTKYPSGGA---------KQLTKILTGKEVPFGKRAVIDDEPLIERVVTL-TGDA-IGTPVLYLLKLAGFKPLMGFTLPSLDVPIVKISEQSCIRCGLCVDACPAGLLPQQ-NHNLFDCIE------------------------CGACAYVCP-------------------SNIPLVQYYRQEKAEIRAL-ESARAAEAKARFEAKQARLAREKLARELRHKQAAVKLTDDQQTVDAAVSRLTRQSDGSESVINIPAAAREARKAQARARQAEKQQA 545

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 6 2 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Comparative analysis of protein domain organization. Genome Res. 2004 Mar;14(3):343-53.