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Query: [O] COG1612 Uncharacterized protein required for cytochrome oxidase assembly, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MVHQSATFNRTGQIMAAISASAPYVARDRDLRNRALVRGWLYVVLLVLFALVLVGGATRLTESGLSITQWQPIHGVIPPLNDAEWQEEFQRYQQIPQYTELNKGMSIEAFKSIFWWEWAHRLLARSVGLVFALPLLFFWVSRRIERGLGPKLVGILLLGGLQGAIGWWMVASGLVDRVSVSQYRLATHLTLAALIFTATMVVARGLAPHSEPAADRSTQRLAGFIVLLALIQIYLGGLVAGLDAGLSYNTWPLMDGKIIPGDLLILEPAWRNFFESPKTVQFVHRLGAYTVFAVALWHMIATRRRLPGSTHARRATLLFVLVLVQASIGIGTLLMQVPLHMALTHQGFALIVLGFAAAHWRGTKGAYPLPQEIVLRSLast
1 -121.000[O] COG1612 Uncharacterized protein required for cytochrome oxidase assembly  ali  100  1MVHQSATFNRTGQIMAAISASAPYVARDRDLRNRALVRGWLYVVLLVLFALVLVGGATRLTESGLSITQWQPIHGVIPPLNDAEWQEEFQRYQQIPQYTELNKGMSIEAFKSIFWWEWAHRLLARSVGLVFALPLLFFWVSRRIERGLGPKLVGILLLGGLQGAIGWWMVASGLVDRVSVSQYRLATHLTLAALIFTATMVVARGLAPHSEPAADRSTQRLAGFIVLLALIQIYLGGLVAGLDAGLSYNTWPLMDGKIIPGDLLILEPAWRNFFESPKTVQFVHRLGAYTVFAVALWHMIATRRRLPGSTHARRATLLFVLVLVQASIGIGTLLMQVPLHMALTHQGFALIVLGFAAAHWRGTKGAYPLPQEIVLRS 377
2 -100.000[O] KOG2725 Cytochrome oxidase assembly factor COX15  ali follow..  33  51.KTVSIRPFSLSSPVFKPHVASESNPIESRLKTSKNVAYWLIGTSGLVFGIVVLGGLTRLTESGLSITEWKPVTGTLPPMNQKEWEEEFIKYKESPEFKLLNSHIDLDEFKFIFFMEWIHRLWGRAIGAVFILPAVYFAVSKKTSGHVNKRLFGLAGLLGLQGFVGWWMVKSGLDQEQLVSQYRLTTHLGTAFFLYMGMLWTGLEILRELDNPAIGPMRKISLALLAVSFLTAMSGGMVAGLDAGWVYNTWPKMGERWFPSSRELMDENWRNLLENPVTVQLVHRTCAYVAFTSVLAAHMYAIKKKIPRNAMTSLHVMMGVVTLQATLGILTILYLVPISLASIHQAGALALLTSSLVFASQLRKPRAPMRNVIITL 463
3 -9.090[O] COG1928 Dolichyl-phosphate-mannose--protein O-mannosyl transferase  ali follow..  9  18....LIWRTPIVKEELEDADNFLKDDAELYDKVKNESAVSHLDTIVMPIIFTVLGMFTRMYK--IGRNNWDEAHDVHPPLGKMLVGLSGYLAGYNGSWDFPSGEVYPDYIDYVKM-----RLFQAMFSSLCVPLAYFTGRAIGFSRLS---VWLFTILVIFENSY------------ATLGKFILLDSMLLFFTVSSYFCLAKFHTMRKSPFSAR----------LWLCLTGLNLGCAISVKMVGL----------------------------------------FIISVVGIYTISELWNLLSDRSVSWKVYVNHWLARIFGLIIIPVCVFLLCFKIHFDLLSNSG............................. 309
4 -9.030[O] KOG3359 Dolichyl-phosphate-mannose:protein O-mannosyl transferase  ali follow..  9  22.TLRQRESSSISVSEELSSADERDAEDFSKEKPAAQSSLLRLESVVMPVIFTALALFTRMYK--IGINNWDEAH-DVHPPLGKMLVGLSGYLAGYNGSWDFLLEIYPDYLDYVKM-----RLFNASFSALCVPLAYFTAKAIGFSLPT---VWLMTVLVLFENSY------------STLGRFILLDSMLLFFTVASFFSFVMFHNQRSKPFSRK----------KWLLITGISLGCTISVKMVGLF--------------------------------------IITMVGIYTVIDLWTFLKSMSWKTYINHWLARIFGLIIVPFCIFLLCFKIHF........................................ 308
5 -8.720[C] COG1969 Ni,Fe-hydrogenase I cytochrome b subunit  ali follow..  8  18.........................................................................................................................................................................................................................VRIWHWLTVLCMAVLMVTGYFIGKPLPSVSGEA---------------------TYLFYMGYIRLIHFSAGMVFTVVLLMRIYWAFDIGHNPIAQAAMFGYFLMSVFMIITGFALWTGGNSMDIHSWHRLGMWLIGAFVIGHVYMALREDIMSDDTVIST 216
6 -8.300[C] COG2864 Cytochrome b subunit of formate dehydrogenase  ali follow..  8  2.........................................................................................................................................................................................................SKIEISNDTRIIRHRTPARISHWMLVICFFMTMFTGVA----------------------FFFPDFAWLTEILGTPQIARAIHPFTGILMFFAFIYLALLYWDHKYNLGQKMLFWTLNLAMVTLLVTGIIMWRQYF--IAILLHSASAFMLFTGILVHIYMAFWVKGSIRGI.... 188
7 -7.650[S] COG5522 Predicted integral membrane protein  ali follow..  12  21.......................................................................................................................HVVTLAIISLLAILLFLFQDEVKQPRASRFLRSLFVFLLLGSQIGYQIWMVATDRWSVRTSLPLQLSDLSVYLSAIMLVTKSR---------------------KLFVFLFFVGIGSSIQALATPDLGMFSFPHIR----------------------ILFFISHGSVFLSCLLMAVIGTYRMGQRSLWVTVLLVNVYGVCIFLIDRWLGANYMYLTKKPGGSSLYIVSAEAITIASFFILYWL.............. 231
8 -7.310[C] COG1271 Cytochrome bd-type quinol oxidase, subunit 1  ali follow..  14  22......................................................................................................................FHMLWPVLTGMGIYLVIIEGLDYYHHARFWARLYVLNFGIGVATGLPPFSESVGDFFGTVLGFEGTMAFMLEASFLGIMLFGWDRVPPLIH-----------------YLATILVAIGANLSTILSANSWLQTPA--GGIFVDGKFVVQDYFAAIANPFMVNSFLHMFFATLETSMFVIGGISAWCILTGRSLQVILVVVMAVAPLQIFIG-EQVSVHQPAKLAAME................................ 259
9 -7.060[S] KOG2970 Predicted membrane protein  ali follow..  8  1.......................................MRVLRNFTIFFLFTALSLFRQISASAG-PVYVSCVNRCIENKCHGNPSDTSNCGYECEITAENYFAAHNLPSQQYHGKWFIRVFGSMLNFMIHYNGYHIMRRCIPDEHPAKRLCLSWAIVGMNAWVWSSVFHIRDTPITEKLDYFSAGAFVLFGSYCTLILMLRLDQLPGGK--------------LLCWIIGVIFIAAFIAHVSYLSFYSF-----------------------------DYGYNMKANVAVGLVQNILWYYYSWSNRNSGLYWTRWPAYIVTSLMLATSLELFDFSPIA-ALWHLSTVPITHYLYGFVVRKCSYDLTKGTFKIKAY 327
10 -7.050[O] COG1138 Cytochrome c biogenesis factor  ali follow..  12  206..................................RFTRPWTLAAWIFLTLGIVLGSAWAYYELGWG---W-------------------------------------------FWDPVEN---ASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLVSVHA--LAFMVLVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTL------------LPLVHKQLGLGSISIGEPFFNTMF-----------LMVPFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVAMTVVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVD. 522
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Robinson-Rechavi M, Godzik A. Structural Genomics of Thermotoga maritima Proteins Shows that Contact Order Is a Major Determinant of Protein Thermostability. Structure (Camb). 2005 Jun;13(6):857-60.