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Query: [M] COG1861 Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNDILFIIQARMGSTRLPGKVLRPLGSNRLLDILVHRVRQSAFYQKDRDNLVIATSDKETDDILEAHCIKQGFRVFRGSEERVLDRFVKVIEAVKPSVIIRLTGDNPFVDPELLDVMIQAHFDQGSDYTYILNAPLGICGEVVNANLLIDISRIQALEDQYQEHVTLYIRNHPALYRVQFLEAPERFRAPQYRLTIDTKEDYESIKALYQKAGERPDVSASELITLLNRNPDAATETRGLast
1 -112.000[M] COG1861 Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog  ali  100  1MNDILFIIQARMGSTRLPGKVLRPLGSNRLLDILVHRVRQSAFYQKDRDNLVIATSDKETDDILEAHCIKQGFRVFRGSEERVLDRFVKVIEAVKPSVIIRLTGDNPFVDPELLDVMIQAHFDQGSDYTYILNAPLGICGEVVNANLLIDISRIQALEDQYQEHVTLYIRNHPALYRVQFLEAPERFRAPQYRLTIDTKEDYESIKALYQKAGERPDVSASELITLLNRNPDAATETRG 239
2 -42.800[M] COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase  ali follow..  18  1MTNFTVIIPARYASTRLPGKPLAEIAGKPMIAHVFEKAMQSG-----AKRVIVATDHEQVATVARGFGAE--VCMTSETHQSGTERLAEVVEKLGIEIIVNIQGDEPLIPPAIVRQVAENLAKYQVK-MASLAVNITDPEELFNPNAVKVLTDHAGYVLYFSRHIGIYAYRAGFIKQYIQWQLEQIESLEQLRVGVDTAEDLEKVRSILEK............................ 258
3 -27.400[M] COG1083 CMP-N-acetylneuraminic acid synthetase  ali follow..  14  4IMTRIAIIPARAGSKGIKDKNLQLVGGVSLVGRAILAAQESGM----FDQIVVTSD----GENILKEATKYGAKPVARPESDAILHCLETLNI-SQGTAALLQPTSPLRNALDIRNAMEIFLGGKYKSVVSACECEHHPYKSFTLEG-DFESPRQKLPKSYRANGAIYINDIQSLFEEKRFFIAPMRFYTYRSIDIDSTLDLQLAESLISK............................ 226
4 -21.800[H] COG2266 GTP:adenosylcobinamide-phosphate guanylyltransferase  ali follow..  11  1...MLTLLMCGGKGTRLGRKPLFEVCGMKLIDHSLLQYKDFD------VIAITSPHTPATESYLAEKGVEVYRAAGKGYIEDYSEACRELAIN---EPVIVASADIVYIRDIAFDIVDA-YMKTIKPALTVVMEGEPVGVNIIDSLLINTWQEEEIYSIE-----------------------------KDSVVNVNTVADVERAERLWTTMRKERG...................... 177
5 -19.600[H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A  ali follow..  10  2..KHVNVLLAGGASRRF-PKAFVKWKGRMLYECAKEALG---------EQTVIISRPEFIDRFQENGENEVYQDAEPFQGMGPLAGIYTAFKKTDGDLYTVLSCDTPLIQRRTMLELKRLMIAGADAVVPISDGQVQPLIAIYHKRIMPVLYDQLSEKRLRISDL--------GRISVCYVQAENIGANPAEFININTRDDFSCLEEKSNSLKRD........................ 199
6 -18.200[R] COG2068 Uncharacterized MobA-related protein  ali follow..  14  10..KVGIVLLAAGRSSRMPNKLLALFDGKPLVRRTAERALGSK-----ASGTIVVTGHQR--ERVRAALSGLDVTFANGLSTSLKAGIAYLPE--DTAGAMIVLGDMPGVVSGDLDRLIDAFRKAGGNSVVRASHQGKRGNPVLLPRALFPAIAHLEGDTGARH----LVEAEGLDVVDVEIG-------EGASVDVDTREALEGAGGVLQD............................ 206
7 -17.900[I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase  ali follow..  9  10.RRIVAVVPAAGIGSRMQMKQYLHIHGKTILEHTLSVLLGY----PLIEKIILAVAANDPYISTCPLLTHPKIQLVEGGSSNGLNAVKSAVQNSEDFWVMVHDAARPCLTHQDLDKLVQVEDQN------------GAILAIPATDTIKRA-LHNQQIHYTEDRSQLWLAQTPQFFPIATLAQALEQALAQ-NIKVTRPEDFALAEFYLSR............................ 236
8 -15.800[S] COG1920 Uncharacterized conserved protein  ali follow..  14  2..KTCAIIPVSHAKTRL-SPTLSPSEREGLLKAMLMDV--SGALARHVDRVLVISA----DEDVLEYAYSLGLKILEEEGERDLNGALEQAMDFEFDRVIITPSDIPLIGKADVSNLLDHA--SRADVVIAPANGGGTNTLILRPSAMSLRFGDCSFFEHIHEARERGL---------------SVYDSFYLSLDVNTAEDLGEIIL................................ 190
9 -12.700[M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)  ali follow..  14  3QNTLNIVILAAGKGTRMYSKVLHEIGGETMLGRVIDTAAALN-----PQNICVVVGHGK--EQVLDTVKRDVVWVEQTEQLGTGHAVKTALPHLAEGRTLVLYGDVPLIDVETLETLLEAAGNEVGLLTDVPADPSGLGRIIRDSSSVTAIVEEKDADAAQKANTGILVLPNAKLEAWLN-SLSSNNAQGEYYLTVNNKLQLAELERIFQT............................ 240
10 -12.600[M] COG1209 dTDP-glucose pyrophosphorylase  ali follow..  16  1MKMRKGIILAGGSGTRLPSKQLLPIYDKPMIYYPLSTLMLAG-----IRDILIISTPQDTPRFQQLLGDGSQWGLVQPSPDGLAQAFIIGEEFIGGDDCALVLGDNIFYGHDLPKLMEAAVNKESGATVFAYHVNDPERYGVVEFDKAISLEEKPLEPKSNYAVTGLYFYDND.................................................................. 182
11 -12.400[M] COG4750 CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes  ali follow..  14  1...MKAIILAAGLGTRLP-KALVQVNQKPLIEYQIEFLKEKG-----INDIIIIVGYLK--EQFDYLKEKYGVRLVFNDKYADYNNLYLVKEELANSYVI-YLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYSGVSFWDAPTAEKIVSFIDKAYVSGEFVDLY-WDNMVKDNIKELDVYVEELEGNSIYEIDSVQDYRKLEEILKN............................ 227
12 -12.200[M] COG1213 Predicted sugar nucleotidyltransferases  ali follow..  13  1...MEAVILAAGFGSRLP-KALLKIGKRPLIYYTVQTLMENG-----IRDVVVVTGHKG--YVLREYLSQFDLNF-LYKKTNNIYSLYLAMDHVSKGFYI-LNSD--LFHPGIFRELHSSTKENLILSVDTFKELGEEEMKVIEDGVVKRISKQLNPSEADGEYIGIARVEENIIDDLYNHVSRVMERKGR--IEIDTPADLMKARYEI.............................. 235
13 -10.900[S] COG3222 Uncharacterized protein conserved in bacteria  ali follow..  13  3CLPVSVLVVAKA-KTRLAAAIGDKVAADIAAAALLDTLDAVAAAPVTARAVALTGDLDSAADSAEIRRRLKSFTVFRQRGDAFADRLANAVDAADGYPVLQIGMDTPQVTAELLADCARLL--LQIPAVLGLAFDGGWWVLGIRTPTAAECLR---AVPMSQPDTGELTLKALRDNGIDVTLVQRLGD-------FDIVDDIALVRDCCA............................. 206
14 -10.700[J] KOG1462 Translation initiation factor 2B, gamma subunit (eIF-2Bgamma/GCD1)  ali follow..  6  37.IEFQAVVFAGFGNSLYP-KALLPIGNKPMLHYPLYWLEAAG-----FTSAILICMEEAEA-APTILDDSKSSADALRAVSHLIKSQKMLTDTHQNDFVC-LSCD--SIVGLPPIYGLDKFRLDNPSALA----------------VYSPVLKYEHITSQSKEIDAKQLIGIEEKTSRLLYAKSSADVGSDFTFRMSLLWKHPRVTLNTNLSDAHIFVFKHWVIDLIREKESISSIRGD 275
15 -10.500[GMO] KOG1460 GDP-mannose pyrophosphorylase  ali follow..  15  10..VAVIMVGGPTKGTRF--KPLFPIAGQPMVHHPISACKRIPN----LAQIYLVGFYEERALYVSAISNELKVPVRYLREDGGLYHFRNLIMEDSPSHIFLLNCD--VCCSFPLPKMLEAHRGYGGIGTPESASQFGELVADPVTNELLHYTEKPETFVSDRINCGVYVFTPKRVSSFEALQPATRIPTDFVRLDQDILSPLAGKKRLYTYETMDFWEQIKSPGMSLRCSGLYLS.... 276
16 -10.500[M] COG1210 UDP-glucose pyrophosphorylase  ali follow..  14  1MRKKVAVIPAAGLGTRFP-KEMLPIVDKPAIQYIVEEAAESG-----IEDILIITGRNKRSKEMQQIADLANIHYIRQKEPLGLGHAVLCAEHFGDEPFAVLLGDDIMVETPALRQLMDVYDVYGTEVVGVQSVLPGIINTSGSQGHVYEVNDSPEEAPSEIAVMGRYVLN-SSIFSV--LKTIGRGAGNEIQLT-DALREVCRKEPIHARLLEGNRYDIGDKLGCFKASTEIGLMRPE 275
17 -9.610[M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate guanylyltransferase  ali follow..  14  82PKNVASIILGGGAGTRL-AKPAVPIGGCRLIDIPMSNCINSG-----IRKIFILTQFNSFS-AATQTSGDAGKKWFQGTADAVRQWVFEDAKTKNVEHVLILSGD--HLYRMDYMNFVQKHIESNADITVSCLLKIDQSGKIIQFTSILGLPPKEAAESPYIASMGVYVFRKEVLLKLLRSSYPTSNDFGS-----EIIPLAVGEHNVQAFLFNDYWEDIGTIGSFFDANLALTE.... 364
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 3 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Erlandsen H, Godzik A. HEPN: a common domain in bacterial drug resistance and human neurodegenerative proteins. Trends Biochem Sci. 2003 May;28(5):224-6. Review.