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Query: [R] COG2068 Uncharacterized MobA-related protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst EPLPAKSRLKVGIVLLAAGRSSRMGGPNKLLALFDGKPLVRRTAERALGSKASGTIVVTGHQRERVRAALSGLDVTFADNPDFANGLSTSLKAGIAYLPEDTAGAMIVLGDMPGVVSGDLDRLIDAFRKAGGNSVVRASHQGKRGNPVLLPRALFPAIAHLEGDTGARHLVEAEGLDVVDVEIGEGASVDVDTREALEGAGGVLQDLast
1 -88.800[R] COG2068 Uncharacterized MobA-related protein  ali  100  1EPLPAKSRLKVGIVLLAAGRSSRMGGPNKLLALFDGKPLVRRTAERALGSKASGTIVVTGHQRERVRAALSGLDVTFADNPDFANGLSTSLKAGIAYLPEDTAGAMIVLGDMPGVVSGDLDRLIDAFRKAGGNSVVRASHQGKRGNPVLLPRALFPAIAHLEGDTGARHLVEAEGLDVVDVEIGEGASVDVDTREALEGAGGVLQD 206
2 -35.400[H] COG2266 GTP:adenosylcobinamide-phosphate guanylyltransferase  ali follow..  14  1..........MLTLLMCGGKGTRLGRGEKPLFEVCGMKLIDHSLLQYKDFD---VIAITSPHTPATESYLAEKGVEVYRAAG--KGYIEDYSEACRELAIN-EPVIVASADIVYIRDIAFDIVDA-YMKTIKPALTVVMEGEPVGVNIIDSLLI------------------NTWQEEEIYSIEKDSVVNVNTVADVERAERLWTT 171
3 -31.000[H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A  ali follow..  15  1........MKHVNVLLAGGASRRFGEPKAFV-KWKGRMLYECAKEAL----GEQTVIISRPEFIDRFQENGENEVYQDAEPFQGMGPLAGIYTAFKKT--DGDLYTVLSCDTPLIQRRTMLELKRLM--IAGADAVVPISDGQV-QPLIYHKRIMPVLYDQEKRLRISDLLGRISVCYVNIGANPAEFININTRDDFSCLEEKSNS 195
4 -22.700[M] COG1213 Predicted sugar nucleotidyltransferases  ali follow..  21  1..........MEAVILAAGFGSRLGEIPKALLKIGKRPLIYYTVQTLMENGIRDVVVVTGHKGYVLREYLSQLNFKFVHNSLYKKNNIYSLYLAMDHVSKG---FYILNSDV-LFHPGIFRELHSSTKENLILSVDTFKELGEEEMKVKIEDGVVKRISKQLNPSEADQSMMDDGIAVYYETTKGLPWIEIDTPADLMKARYEI.. 235
5 -22.000[M] COG4750 CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes  ali follow..  16  1..........MKAIILAAGLGTRLRNTPKALVQVNQKPLIEYQIEFLKEKGINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADNNFYSLYLVKEELANS----YVIDADNYLFKNMFRNDLTRSLVYGDDYKVQDIIVDSKAGR-SFWDAPTAEKIVSFIDKAYVSGEFVDKELDVYVEELEGNSIYEIDSVQDYRKLEEILKN 227
6 -20.800[M] COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase  ali follow..  21  3.........NFTVIIPARYASTRL--PGKPLAEIAGKPMIAHVFEKAMQSGAKRVIVAT--DHEQVATVARGFGAEVCMTSETHQSGTERLAEVVEKLGIAEDEIIVNIGDEPLIPPAIVRQVAENLAKYQVKMAAVKVLTDHAGYVLYFSRAPIPVLEQIESLEQLRVL--WYGEKIHVELAREVPPVGVDTAEDLEKVRSILEK 258
7 -20.600[M] COG1083 CMP-N-acetylneuraminic acid synthetase  ali follow..  17  3......IIMTRIAIIPARAGSKGI--KDKNLQLVGGVSLVGRAILAAQESGMFDQIVV-TSDGENILKEATKYGAKPVARPESLAQSDTRILHCLETLNISQGTAALLQPTSPLRNALDIRNAMEIFLGGKYKSVVSACLEGTEVQPIHELTDFEQKLPKSYRANGAIYINDIQIAPMRFYLMPTYRSIDIDSTLDLQLAESLISK 226
8 -18.700[S] COG1920 Uncharacterized conserved protein  ali follow..  16  1........MKTCAIIPVSRFTHAKTRLSPTLSPSEREGLLKAMLMDVSGALARHV-VLVISADEDVLEYAYSLGLKILEEEG-ERDLNGALEQAMDFCAPEFDRVIITPSDIPLIGKADVSNLLDHASRAD--VVIAPANGG--GTNTLILRPSAMSLRFGDCSFFEHIHEARERGLSVSVYDSFYLSLDVNTAEDLGEIILH... 191
9 -18.400[M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)  ali follow..  20  2......PQNTLNIVILAAGKGTRMYSKMKVLHEIGGETMLGRVIDTAAALNPQNICVVVGHGKEQVLDTVKR-DVVWVEQTE-QLGTGHAVKTALPHLAAE-GRTLVLYGDVPLIDVETLETLLEAAGNEVGLLTDVPADPSGLGRIIRDSSGSVTAIVEEKDADAAQKAVKEINTGILVLP........................ 175
10 -18.300[I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase  ali follow..  20  6....AKSTRRIVAVVPAAGIGSRMQMDPKQYLHIHGKTILEHTLSVLLGYPLIEKIILAVAANDPYISTCPLLTHPKIQLVEGGSSRADSVLNGLNAVKSAVEDFWVMVHDRPCLTHQDLDKLVDTIKRALHNQQIHYTEDRSQ-TPQFFPIATLAQALEQALAQGLQSAMEFAGFRPHLVA-GRSDNIKVTRPEDFALAEFYLSR 236
11 -18.100[M] COG1861 Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog  ali follow..  14  3.........DILFIIQARMGSTRL--PGKVLRPLGSNRLLDILVHRVRQSARDNLVIATSDKEDILEAHCIKQGFRVF------RGSEERVLDRFVKVIEKPSVIIRLTGDNPFVDPELLDVMIQAHFDQGSDYTYILNAPLGICGEVVNANLLIDISRIQALEDQYQEYIRNHPALYRVQFLEPQYRLTIDTKEDYESIKALYQK 211
12 -15.400[M] COG1209 dTDP-glucose pyrophosphorylase  ali follow..  16  4..........RKGIILAGGSGTRL-AVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRFQQL-GLNLQYKVQPS-PDGLAQAFIIGEEFIGG--DDCALVLGDNIFYGHDLPKLMEAAVNKESGATVFAYHVNDPERYGVFYDNDVVQMAKNLKPSARGERIYLEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIAT 242
13 -13.600[M] COG1210 UDP-glucose pyrophosphorylase  ali follow..  17  8............AVIPAAGLGTRF-AQPKEMLPIVDKPAIQYIVEEAAESGIEDILIITGRNKRSIEDHFDRANIHYIRQKE-PLGLGHAVLCAEHFIGD--EPFAVLLGDD-VSETPALRQLMDVYDVYGTEVVGVQSVLPED-KPYVLNSSIFSVLKTIGRGAGNEIQLTDALREVCR----EGNRYDIGDKLGCFKA...... 265
14 -12.800[MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)  ali follow..  16  1..........MRAVLMAGGSGTRLRDLPKPMVPILNRPIAEHIINLLKRHHITEVIATLHYLPDVLRDYFQGVQMTYAVEEDQPLGTAGCVKNIAELLD---ETFLVISGDS--ITDFDLGEAIAFHKQKQSKATLIPSTSEIFSDTVILEPEVLEYLPSNTECDFSKDLFPLLLAKDEPM-VAEGYWCDVGHLDAYREAQYDGLD 234
15 -12.200[S] COG3222 Uncharacterized protein conserved in bacteria  ali follow..  14  2......SCLPVSVLVVA--KAPEPGRVKTRLAAAIGAAALLDTLDAVAAAPVTARAVALTGDSAADSAEIRRRLKSFTVFRQRGDAFADRLANAHVDA--DGYPVLQIGMDTPQVTAELLADCARLLLQIP--AVLGLAFDG--GIRTPTAAECLRAVPMSQPDTGELTLKALRDNGIDVTLVQR--LGDFDIVDDIALVRDCCAP 207
16 -11.100[J] KOG1461 Translation initiation factor 2B, epsilon subunit (eIF-2Bepsilon/GCD6)  ali follow..  15  19....QSRRQRLQAILLADSFATKL-ERPNVLLPLVNIPMIDYTLAWLESAGIEEVFVFCSMQVIDYLNNSDDFTVKTIESPQNSTSAGDALRYIYEQQIETSGDFVLVNGCI--VSNMPLTQLIQEHRDRKKK......................................................................... 157
17 -10.600[GMO] KOG1460 GDP-mannose pyrophosphorylase  ali follow..  15  1..MGSSMEEKVVAVIMVGGKGTRFRNIPKPLFPIAGQPMVHHPISACKRIPLAQIYLVGFYEEREFALYVSAISNELKVPVRYLRGSAGGLYHFRNLIMEDSPSHIFLLCDV--CCSFPLPKMLEAHRGYGGIGTLLVI-KVSPESASQFG------ELVADPVTNELLHYTEKPETFVSDRINCGVYV................. 191
18 -10.100[G] COG0448 ADP-glucose pyrophosphorylase  ali follow..  15  13.PNKYELVKDTLVLILAGGRGSRLYRAKPALYFGGNRRIIDFALSNCLNSGLNRIGVVTQYAAHSLLRHLQN-ARQQIDDSTWYRGTADAVYQNMAIIRDHYCPKYILILAGDHIYKQDYSQMLLDHIHSGAKCTVG..................................................................... 169
19 -10.000[J] KOG1462 Translation initiation factor 2B, gamma subunit (eIF-2Bgamma/GCD1)  ali follow..  14  33....QSIPIEFQAVVFA-GFGNSLDALPKALLPIGNKPMLHYPLYWLEAAGFTSAILICMEEAEAHINAWMRIHVEAPTILDDSKSSADALRAVSHLIKSQQNDFVCLSCD--SIVGLPPIYGLDKFRLDNPSALAV..................................................................... 183
20 -9.770[M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate guanylyltransferase  ali follow..  12  77..TQNADPKNVASIILGGGAGTRLFKRAKPAVPIGGCRLIDIPMSNCINSGIRKIFILTQFNSFSLNRHLSR-QTSGDAGKKWFQGTADAVRQFIWVFTKNVEHVLILSGDH--LYRMDYMNFVQKHIESNADITVSCL-------PMDESRASDFGLLKIDQSGKIIQFSEKPKGDDLKAMQVDTSILGLPPKEA.......... 290
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 3 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Erlandsen H, Godzik A. HEPN: a common domain in bacterial drug resistance and human neurodegenerative proteins. Trends Biochem Sci. 2003 May;28(5):224-6. Review.