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Query: [P] COG2111 Multisubunit Na+/H+ antiporter, MnhB subunit, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst FRKELWKIAETSPFPIATGNDILSMLVYRANLLGKFFGRMADSMSPRRHLVSLIVLLWALAAFATIHPSVQLAPKQPGIDRWIDLIPLAIIALSVFGLLTTRNRLSAAVLVGTVGVGVSFQMLLLGAPDVALTQFLVEGLVVVIIMMVVRHQPANFKRIKPSRRRSTVLVAVLAAFAAFMAVWGLLGRHERSELAMWYLNQGPEITSGANVVNTILVEFRALDTLGELSVLGMAAVVIGAMVASMPRHPFAKGTHPRPFGQSQLNSIPLRMLLKVLVPALCFLSFMVFMRGHNDPGGGFIAALIAGGALMLLYLSKAKDGRIFRPNVPFILTGAGILMAVFSGVLGLTHGSFLYAIHFNFVGQHWTTSMIFDLGVYLAVLGMVSMAINGLGGYLRPGTDIADLDYARRSGPLPATPTVEPEPEGDEDWPEPINPAGDNKEEANRLast
1 -113.000[P] COG2111 Multisubunit Na+/H+ antiporter, MnhB subunit  ali  100  1FRKELWKIAETSPFPIATGNDILSMLVYRANLLGKFFGRMADSMSPRRHLVSLIVLLWALAAFATIHPSVQLAPKQPGIDRWIDLIPLAIIALSVFGLLTTRNRLSAAVLVGTVGVGVSFQMLLLGAPDVALTQFLVEGLVVVIIMMVVRHQPANFKRIKPSRRRSTVLVAVLAAFAAFMAVWGLLGRHERSELAMWYLNQGPEITSGANVVNTILVEFRALDTLGELSVLGMAAVVIGAMVASMPRHPFAKGTHPRPFGQSQLNSIPLRMLLKVLVPALCFLSFMVFMRGHNDPGGGFIAALIAGGALMLLYLSKAKDGRIFRPNVPFILTGAGILMAVFSGVLGLTHGSFLYAIHFNFVGQHWTTSMIFDLGVYLAVLGMVSMAINGLGGYLRPGTDIADLDYARRSGPLPATPTVEPEPEGDEDWPEPINPAGDNKEEANR 444
2 -23.300[P] COG1563 Predicted subunit of the Multisubunit Na+/H+ antiporter  ali follow..  27  4...........................................................................KMTKYDLFIYIITALLPLSACLLIVQVNPYHALVIRGILGAVAALAYTLLGAADVALTEALVGTMLAITLYAIAVR..................................................................................................................................................................................................................................................................................................... 79
3 -18.300[C] COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J)  ali follow..  9  11....................................................................................YLFAFVAVASAFMVISSRNPVHSVLFLILTFFNAAGLFMLTGAEFLAMILLVVYVGAVMVLFLFVVMMLDVDFAEMKEGALQYAPIGALVGLILAAELIIVLGGYTFAPKLA--IPDLATRSNTAALGDILYTDY-YFQISG--LILLVAMIGAIVLTLRHKEGVKRQSIAAQVGRTPATGMEIRKV............................................................................................................................................................................. 200
4 -11.000[S] COG4039 Predicted membrane protein  ali follow..  17  11..................................................................................ITNVGVFVIFTGAAGIILLSRPLDKIIMFSLLQGGFVMVLAAARYLDVAMAAALFDPISTIILLMAVMRI.................................................................................................................................................................................................................................................................................................... 80
5 -9.420[R] COG3907 PAP2 (acid phosphatase) superfamily protein  ali follow..  9  1...........................................................................................................................MITVPLFATSASGHTVKISKTTRQASTGPSTLNNRSTVPTIKTISLQVFGLLLVGLLFLALSRSEQLDWLISNYWFDPVGQNFPWEH--------LDLLNHRLLKMALIATAIAALLWGIYRRNGR-------------------LVTTALLFGLGPLVIGILKATSAHSCPGGCFPGG--ASSGFAVMALFF----YPERPRLAMLCWFAGIGLGMLMGFGQIMRGAHFL------------THNLWAGWWVWLSQLAAFWIISGYYQRIKGTE.............................................. 271
6 -9.000[P] KOG4505 Na+/H+ antiporter  ali follow..  11  16....................................................................................AIIGGFTSLFMLCSLIIKEKLGEATMATATGLIFGLFVPTSWGNTDYITEELARVLLVVEVFAAGAELPRAYMLRHWRSMFVMLLPVMIFGWLVSSLAIAACITATDPVLASSIVGKGKFARRVPGHLRNMLLAESGCDGMAIPFLYL-----AIYLIIEKPARHAGRDWVCIIILYECTFGCVLGAIIGVIA-FYFVLALFCGGIGTIIGVDDLLVSFCAGAAFSWDSWFSKKTEESHVSNVIDLLLNLSFFVYV---------GAIMPWPQFHMPHMDLSVWRLVVLAICILIARRIPAVL......................................................... 346
7 -8.590[P] COG1006 Multisubunit Na+/H+ antiporter, MnhC subunit  ali follow..  16  6....................................................................................SILIGLIFAAAVYLILSKSLLRIIIGTAVLSHGVNLLVLTMGGLKLILTAIVISFGVTAFFLVLAYRA.................................................................................................................................................................................................................................................................................................... 95
8 -8.000[S] COG4036 Predicted membrane protein  ali follow..  11  34.........................................................................................................................................................................PAIYTGLIAGFIALLGISFQKND--------SALIITDIVGIAMLVIVAAVGTD-LAEALILPGLVVELAEIMAISEILISREMRILGEVPVVEHRPMVFRTAPNFLALILIAYGVFLT---------GFTGGAVAGAGILFYVATRRARGLPTVEDGIAGISGVTWCLWLAGFLIFFTAPQLWL-----PALFMSGCGILIKVASKMGLIGVL............................................................. 229
9 -7.820[S] COG3238 Uncharacterized protein conserved in bacteria  ali follow..  10  9.....................................................................................PLLMLATILAGMLSPMQSAVNGQLGHWLQDGNAC-----------AVISFASGLVVMFFIIIARKETRQQFASIPTLIKKRKIPLWNWFAGLCGAMVVFSEGASASALGVATFQTALI----SALLLSGLLCDRFGI-TPWRITGALFAVIATIFVVSPQWHSTSF-QPAGNAKVAEATGSMLVSITWNFIVGFCVLGAALAIRIALPDTWWMYLGGPLGLLSIGLMAIL---------------VRGLGLLMLGVASTAGQLLGSVLIDELIPSLGNTVYLVTI--IGTLFALVGAIVTTIPEYRASKMAQRIEVSE......................................... 323
10 -7.790[I] KOG3750 Inositol phospholipid synthesis protein, Scs3p  ali follow..  11  2....................................................................................EHLERCEWLLRGTLVRAAVRRYLPWALVASMLAGSLLKELSPLPE-VLNVYFVKVAFCLLLPFIALTNYHLTGKAGLVLRRLSTLLVGTAIWYICTSIFSNIEHYTGSCYQSPALEGVRKEHQSKQQCHQEGGFWHGFDISGHSFLLTFCAL----MIVEEMSVLHEVKTDRSHCLHTAITTLVVALGILTFIWVLMFLCTAVYFHNLSQKVFGTLFGLLS........................................................................................................................................... 229
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Flexible structure alignment by chaining aligned fragment pairs allowing twists. Bioinformatics. 2003 Oct;19 Suppl 2:II246-II255.