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Query: [S] COG2121 Uncharacterized protein conserved in bacteria, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSLKFFRKNIVLKVVPRLAFGVLWLLHKTCKNRYFLAQDLKEKPFIVSCWHGELGMIGFAYLRLQKPSVYVIASQHFDGSIAAGLFESFGFKNIRGSSKKGGVKVLIEGLKRLKEGCDVAITPDGPKGPRHSIADGVIALAQKSGVGISACRVVCKNAWRLNTWDQFEIPKPFSEVRYYMLESVIIPKEWELSKAKEYLKTRMDSVGFEESQRGLGALast
1 -87.900[S] COG2121 Uncharacterized protein conserved in bacteria  ali  100  1MSLKFFRKNIVLKVVPRLAFGVLWLLHKTCKNRYFLAQDLKEKPFIVSCWHGELGMIGFAYLRLQKPSVYVIASQHFDGSIAAGLFESFGFKNIRGSSKKGGVKVLIEGLKRLKEGCDVAITPDGPKGPRHSIADGVIALAQKSGVGISACRVVCKNAWRLNTWDQFEIPKPFSEVRYYMLESVIIPKEWELSKAKEYLKTRMDSVGFEESQRGLGA 217
2 -24.200[I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase  ali follow..  8  41..GSVARQLAARRIIGTSWRLFVAYLKWSLEVSFKGVEKLNRPGQLILANHPSLLDVVLLVGHVPEMNC-IVKKDLQHNPAMSSQIKGAGYIPNEESE-----AMLETVKAVFDSGQSLLVFPEGTRDGRVKMHRGAVSLGLRYAEVITPVCIKMNPPNFKKGQPWYRIPPKRIRYEITVGDDILPQDWLAEKPLPIAARRLNEYLQDYFTR..... 249
3 -20.700[I] KOG2848 1-acyl-sn-glycerol-3-phosphate acyltransferase  ali follow..  11  85.............................FRFKIENEEILRHKSAVLVVNHQSELDILAIGRTFGPNYSVIAKKSLRYVPILGWFMILSDVVFIDRSRRSDAIQLFAKAARRMKENISIWVFAEGTRSYSLKLKKGAFHLAVQAQVPIIPIAIQTYG----HLFHPPTKVFNKGEALIKVLDPIPTETAEDVNDLLHETETAMNNALVEIDDYGKVK 277
4 -16.600[I] KOG4321 Predicted phosphate acyltransferases  ali follow..  11  98.................IASFWDGVGNVWHGYELRGIENVPEGSALFIYYHGCLYYLISKLVIHKNRSLHCVGDKF---PGWRPLCKLFS--ITSGTVE--------ECTEELKEGNLLCIAPGGVREALFS-RLGFAKVIIGSKTPVIPMFTENCRESFRTPEWGRSFGFP-VKMITHLGKPIYFDFDVTPEEVRKTVKREIRMMIKEHQRLPGS. 319
5 -12.900[I] KOG2898 Predicted phosphate acyltransferase, contains PlsC domain  ali follow..  12  128.....LRKKIERVLVEMICSFFVASW--TGVVKYHGPRPSIRPKQVYVANHTSMI--FIVLEQMTAFAVIMQKHPGWVGLLQSTILESVGCIWFNRSEAKDREIVAKKLRDHVQGADPLLIFPEGTCVNNNYTKKGAFEL----DCTVCPIAIKYNKIFVDAFWN-QLMTSWAVVCEVWYLEPQTIRPGETGIEFAERVRDMISL............ 335
6 -12.700[R] COG4261 Predicted acyltransferase  ali follow..  15  101..............................RVRFDDPAPFSGRGALVIGAHGNLEMTRALATRHGQVKVTAVVYIEHANRVLAGAHPEFATHLL--EVSDFGPATAMRMQERIDAGELLVIVGD---GAPARFAQGPYILAHALGCPVYLF-------FCLKTRQDYTL------------EPFAERIELPRHARATHLATLAQRYASRLEHHCRKA 290
7 -12.000[I] COG2937 Glycerol-3-phosphate O-acyltransferase  ali follow..  10  260.......SYEMIRLTDRILGFTWNRLYQGINVERVRQLAHDGHEIVYVPCHRSYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLTVFREYLGLFSRGYSVEYFVEGGRGRLLDPKTGTLSMTIQAPITLVPIYIGYEHVMEVGTYAKELRGATLGQGYVNFGEPMPLMTAIRPAWLTPTVNSIAADLMVRINNAG... 520
8 -11.700[M] COG1560 Lauroyl/myristoyl acyltransferase  ali follow..  9  117..............................RGELIGEENLSGERVILLVPHSWAIDYAAVMLAARGYKVANIMKPQRNDWLMHVQRMQYGGRIFTRES------GIKPFLRSIQSGYVGYWVPDEDHGPQNSV-KGFGKMAKLCKAHVVPLMSCYNSD---------------GRYEVHILPALQNFPTGDEEADALAMNRAIEALVTPQPE..... 297
9 -11.700[I] KOG3729 Mitochondrial glycerol-3-phosphate acyltransferase GPAT  ali follow..  14  213.......NNGLLAFTSWILYKLLPCFLSGVVTNTKQIEMLKGTPLIFVPLHRSYIMVTWILTNNDIRSPLVAAGNNLQIPVFGGLLRGLGAFFIKRKPVEGKKDVLYRAAHALKQGHNVEFFIEGGRGKPCMPKGGILSVIVNADALLVPVSV---------NYERLALKSNYGLMRIDFNEPYSIRELVNSYNKIAREDGNIAKVYKPSARVLQHN 469
10 -11.000[I] KOG3730 Acyl-CoA:dihydroxyactetone-phosphate acyltransferase DHAPAT  ali follow..  9  101.......NLYNVRSFGYAVCKAMEKLYDGIYVNEKKLLEIKKDCVIFMPSHKTLLLSLICFQYDIQLPAIAAGQDFMSMKFMAGVLRRSGAFFMRRSFGTDQLAVFSEYVQTHNNDRTVEFFVEATRGKSLHPKYGMLQMVLEPDIVIVPVSMNYDKILEEKLYAYELLGFPHGSCFLTFGEPISVRDHFGVSLHRNT................... 332
11 -10.800[I] KOG4666 Predicted phosphate acyltransferase, contains PlsC domain  ali follow..  9  161.................DMDSNPKTTSTEINQKGEAATEEPERPGAIVSNHVSYLDILYHMSA--SFPSFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDFKGVSGTVNSNKSAPTIMLFPEGTTTNGDYLKTGAF----LAGTPVLPVILKYPYERFSVAWDTILLCQVVNHLEVIRLPVYYPSEKDDPKLYASNVRKLMAT............ 362
12 -9.910[I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)  ali follow..  10  104........................................TDKNYLVGI-HGIISMAAWSNFATNGTGIYEKFPGIRWNLCTLALQFRM-LLLLTGLIDCSRESIEYVLDKCGQKGRAVVLVIGGAEEALDASRKGFVREALITGAYLVPVYSFGENQEWCKSIFGISYPIFHGRIDTVVGAPIPVPTKEQIDELHTIYCQKLTELFDEHKEKYG.. 330
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.