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Query: [S] COG2431 Predicted membrane protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFSGLLIILVPLIVGYLIPLRHKAALQLINRLLSWIVYLILFFMGISLAFLDNLASNLVAIFHYSAVSITIILLCNIAALLWLERILPWRHHHQQEKLPSRIAMALESLQLCGVVVLGFVIGLSGLSVLQHATEASEYTLIFLLFLVGIQLRNSGMTLKQIVLNRRGMMVAVVVVASSLLGGVINAFILDLPLKTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELLAIMLIPGLVRRSRSTALGLCGATSMDFTLPVLQRSGGVEIVPAAIVHGFILSLLVPLLMAFFSALast
1 -90.000[S] COG2431 Predicted membrane protein  ali  100  1MFSGLLIILVPLIVGYLIPLRHKAALQLINRLLSWIVYLILFFMGISLAFLDNLASNLVAIFHYSAVSITIILLCNIAALLWLERILPWRHHHQQEKLPSRIAMALESLQLCGVVVLGFVIGLSGLSVLQHATEASEYTLIFLLFLVGIQLRNSGMTLKQIVLNRRGMMVAVVVVASSLLGGVINAFILDLPLKTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELLAIMLIPGLVRRSRSTALGLCGATSMDFTLPVLQRSGGVEIVPAAIVHGFILSLLVPLLMAFFSA 299
2 -8.740[P] KOG4505 Na+/H+ antiporter  ali follow..  14  7........................................................EISKPHLAYAIIGGFTSLFMLCSLIIKEKLFLGE--------------------ATMATATGLIFGPYVAKLFVITEELARVLLVVEVFAAGAELPRA--YMLRHWRSMFVMLLPVMIFGWLVSTGFMYALIPRLSFLESLAIAA----ITATDPVLASSIVGKGKFARRVPGHLRNMLLAMAIPFLYLAIYLIIEKPARHAGRDWVCIIILYE-----CTFGCVLGAIIGVIARKMIKFS.. 233
3 -8.720[R] KOG4821 Predicted Na+-dependent cotransporter  ali follow..  11  25..............................................................................................................FFICLAILIVIARFAPNFARDGGSIGYGCVAWIFLQSGLGMKSRSLMANMLNWRAHATILVLSFLITSSIVYGFCCAVIDDWVLIGLILTATCPTTVASNVIMTTNAGGNS-LLCVCEVFIGNLLGAFITPALVQMFTNRAPFAYGNPATGNGIGA---------LYGRVMKQVGLSVFVPLFVGQVI. 215
4 -6.780[R] KOG2563 Permease of the major facilitator superfamily  ali follow..  12  143.ICMTGQGIAAIAYPFIMFLPTKVAGSWFQRAIATSIGVMSNPLGVLMANL--IVKSPEHVIWLNIFTCVPSLIAMLIATFGVNRSEPKIPPTFSASKPGMKSCFSSKQYIILLIVMGGGIGMF---------NCLYTVMLELLCPSGYSNFFSG-------------VCAALMIVGGVFGAAASSIFVDRTKLYEETLKIALGAAVIFGLIF-----------LQLTLHQGYSVILGVTCLLFGVLGLATYPIGLELASECTFPVSEATSTGLIVLSGQIQSVIYVFIMKNFAR.... 414
5 -6.760[A] KOG2412 Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor  ali follow..  12  289...........................................INPKFGQLTNSNQQLFKIQNELTQLINDTKGDSLAYHWILNFIAKAVVHQAETEVRVKPESALPLGKLTLYLLQELFMARLVKKCPFVIGFTCEIDTEKGRQNMGWKRNNENKWEDNTSYDER-----MGGILSLFAIITRLQLPQEFITTTSHPFPIALSWHILARICNTPLNLITNTHFVILGSWWDKLLILIGEELTSR---MAEKKYVGAARLRILLEAWQNN............................. 528
6 -6.670[R] KOG2140 Uncharacterized conserved protein  ali follow..  11  159.................WEALKKSINGLINKVNISNISIIIQEL-LSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLTQVRNILHESEIDKRVYMIEVMFAV-PLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDTDSNTDQDNLVSFRRTIYLAIQLDFEECAHKLLKMEFPESQTKELC--MILDCCAQQRTYEKFFGLLAGRFC.......... 515
7 -6.610[R] COG0385 Predicted Na+-dependent transporter  ali follow..  19  35......................................................................................................................................ATKIAVGLLFFLHGARLSREAVIAGITHWKLHVTVLASTFVLFPILGLAAGWAISQSPFYTGILYLCVLPSTVQSSIAFTSMARGNV-SAAVVSASASNIFGMFLTPLL--------------------VGLLFAIKGGGGISMDALESILLQLLAPFVLGQVL. 180
8 -6.460[T] KOG2290 Rhomboid family proteins  ali follow..  14  638...................................................................................................................VCGLLPFLNPEVPDQFYRLWLSLFLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLP----YRAEVGPAGSQFGILACLFVEL----FQSWQILARPWRAFFKLLAVVLFL-------FTFGLLPWIDN---------------FAHISGFISGLFLSFAF..... 786
9 -6.390[S] KOG3100 Uncharacterized conserved protein  ali follow..  15  590.....................................................................................................................................................RTLTQIKEKKKNELLQKAVITPDFEKNHCVPPYSESKYQLQKKRRKERQKTAGDGWFGMKAPEMTN-------------ELKNDLKALKM-----------------RASMD---P-FYKKNDRDGFPKYFQIGTIVDNPADFY...... 701
10 -6.270[A] KOG2253 U1 snRNP complex, subunit SNU71 and related PWI-motif proteins  ali follow..  10  450.......................................................................................................................................................................................IPATKGKLFRRKHELFVHRIEWDQLDGKWMNDRIRPWVAVTQFLGEEDKSFCDFICDQIEKQATPQEILKDVAVIIDEDAEQFVIKM----YEGQARRLGIT.............. 554

FFAS is supported by the NIH grant R01-GM087218-01
1 4 5 9 0 4   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Functional differentiation of proteins: implications for structural genomics. Structure. 2007 Apr;15(4):405-15.