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Query: [P] COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MISRRSALVIAAGLSALALASCSGKSDAPAANNEVTFSILSTESTQNMESYWTPILKDMEKQTGLKVKPFFSSNYSSLIVAMGAKQTDLGWFSNQSGLEAVRRSNGEVFARTFDPSGTDGYKSVIIVPADSKIQSVQDLLKCDKSLDFGIGDKKSTSGTLAPMTYVFIPANKKPETCFKTVISANHQANLFAVANGKLDASTNNSTAIGLSKARGEGVTDKIRVIWESPTLPEDPLVWRKDIDPVVKEKLRQFFLTYAQGDTPEAEQQRGYLKRLSIGGFKPADDTHLLVVREMEATEQLGLAREAGDQAKVAAAQKVLDGVKAERLAAEGKAGVVAQPANLast
1 -110.000[P] COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component  ali  100  1MISRRSALVIAAGLSALALASCSGKSDAPAANNEVTFSILSTESTQNMESYWTPILKDMEKQTGLKVKPFFSSNYSSLIVAMGAKQTDLGWFSNQSGLEAVRRSNGEVFARTFDPSGTDGYKSVIIVPADSKIQSVQDLLKCDKSLDFGIGDKKSTSGTLAPMTYVFIPANKKPETCFKTVISANHQANLFAVANGKLDASTNNSTAIGLSKARGEGVTDKIRVIWESPTLPEDPLVWRKDIDPVVKEKLRQFFLTYAQGDTPEAEQQRGYLKRLSIGGFKPADDTHLLVVREMEATEQLGLAREAGDQAKVAAAQKVLDGVKAERLAAEGKAGVVAQPAN 341
2 -21.300[P] COG4521 ABC-type taurine transport system, periplasmic component  ali follow..  15  1..........MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQA----DNTFAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVAASQQVPIEVFLLASKLGNS---EALVVKKT--ISKPEDL----IGKRIAVPFISTTHYSLL---AALKHWGIKPGQVEIVNL--QPPAIIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQV-GQWGAPTLDVWVVRKDFAEKHPEVVKAFSKSAID-----------------AQQPYIANPDVWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQQQTAELTGPVNKAIIDTAQ 295
3 -19.400[P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components  ali follow..  11  8FSRRKFIFTAGASASAVFLKGCLGSAEQAPEVTTVKLGYIPIVESAPL---------IIAKEKGFNVELSKQASWGSARDNVEIGSAGGGIDGGEGLITKGNQKIPMYVLCQLITHGNG--GSGIGLRLASAKSLFSKLKASPTPFTAAQTFPAVNQDFWI--RYWLAAGGIDPDADVKLLTV-PSAQTVANMKTGTMDAFSTGDPWPFRIVKDK-------FMAALTAEIPEEYLAMRSDWHPKATKALLKGLMEAQQ---DNFDNRKELAEIVAARAYFNVPVDVLIDP.................................................. 332
4 -16.600[K] COG3888 Predicted transcriptional regulator  ali follow..  6  41.DLEEKGIIKRRTIGGKIKHVWLAEYYPYYDEKLLRIGCLRSTEYVKFVSVAKNYS----ESKGIDLIVRFYDDAISLMNDLSQGLLEFALAPIFTEIIYSISNRNSIILG-------------AVASGGSGVYKNVNC----NCGKILT--SESSSMMILAREFAKTRK------ISEIAIFKDPRRAIKDYESFKAEYIVIWEPYASKIMGE--------KMASFSDVLDSFPISVSENNREN--RTLIEIVRLYKRSRFTAREDVIDIFAKSSLENYIWDIKFYRSDLKKYLEFIGYPPIEEIIEK................................ 322
5 -16.300[R] COG2358 TRAP-type uncharacterized transport system, periplasmic component  ali follow..  12  1MSLSRRFGLFTLAATVTFSTSVFAAPT--------FINILTGGTSGVYYPIGVGLSQIYGHDIGAKTSVQATKASVENLNLLQAGRGELALALGDSVADAWN--GVADAGFKAPLKKLRAIGNTVVASQASGIKTLADL----KGKRISVGAPKS--GTELNARAIFKAAGLSYEDMGKVEYL-PYAESVELIKNRQLDATLQSSGLGMAAIRD--ASTMPITFVYHAASIPAGTLVSHSGVSDELAYQMTKLMFDNLPRLVTAHAAAKDIALDKAAKN.............................................................. 298
6 -15.500[H] COG2998 ABC-type tungstate transport system, permease component  ali follow..  13  1MEFTMKKTTFTLAAASLILVSYSASS---ADDARIRLATTTSTYDSGL---LDYLLPKFEQDTGYKVDVIATGT-GKALKMGENGDVDLVMTHAPKAEASFVEAGFGVLPRKLMYN-----DFVVVGPESDPIADEKNIAKVFENIAKSFISRGDDSGTHKKELGIWAQNKIEPNFGGYRSIGQGMGPTLNMASEMQAYTLTDRGTWLAYNNKL------ALKILFEGDE-PYQVIIVNPERYPTTQYHAAKVFSDW------VNPKGQQLINEFKVNGFVANADKQ...................................................... 275
7 -15.200[P] COG4150 ABC-type sulfate transport system, periplasmic component  ali follow..  10  1MKQNSVKKNARNGLTHIALFSALILSGVTASATELLNSSYDVSRETALNPGFQAQWEQQNPGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQITDVQILHDRGNLIPADWQARLPNNSSPFAFLVRKGNPIRNWDDLVR--EDVKLVFPNPKTSGNGRYTYLAAWGATQLADGG-VEVFDTGGRGATTTFVERGLGDVLISFESEVNNIRKEYGSDQYEVIVPPVDILAEFPVAWVDKNVEKNGTEKAAKAYLNY-----LYSPPAQQVITRF---NYRVYDKA....................................................... 298
8 -14.900[P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen  ali follow..  11  5FIMKFSLKSLLTIAAAASTLILAGCGEKAVDNNKVKIGVMAGAEAQVAEVAAKVAK----EKYNLDVELVTFTDYVTPNAALDDGSIDANAFQHKPYLDKQIADRGYKLAIVGNTFVYP------IAGYSKQIKSVDEL---QDGARIAVPNDPTNLGRLQQQGLLKLREDVGLLATVRDIVENPKKLEILELDADDVALSIINT---TYASSINLTPEKDGIFVENKESPYVNILVARENVNAENVQNFKKAY---------QTDEVAKAASEIFQGGAVKG.......................................................... 274
9 -14.600[R] COG4134 ABC-type uncharacterized transport system, periplasmic component  ali follow..  7  1.MMRHCGWLLGLLSLFSLATHASDWQEIKNEAKGQTVWFNAWGGDTAINRYLDWVSGEMKTHYAINLKIVRLADAADAVKRIQTGSVDLLWVNGENFRTLKEANLLQTDWAETLPNWRYIARRDVTPQPPQTPQALLEFAKANPGT-VTYPRPPDFTGTAFLEQLLIMLTPDPAAL-EGKDFPPSPARMDALLKAGTFRLSLTFNPAHAQQKIASGDLPASSYSFGFRE--VHFVTIPANANASAAXKVVANFLLS..................................................................................... 323
10 -14.500[ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain  ali follow..  14  1..MKKLVLSLSLVLAFSSATAAFAAIP-----QNIRIGTDPTYAPFESKNS--DLAKELCKRINTQCTF-VENPLDALIPSLKAKKIDAIM---SSLSITEKRQQEIAFTDKLYAAD-----SRLVVAKNSDQPTVESL----KGKRVGVLQGTTQETFGNEHW---------APKGIEIVSYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPVGKDGPSVKDEKLFGVGTGMGLRKE-DNELREALNKAFAEMRADGT............................................................................... 244
11 -14.300[P] COG1613 ABC-type sulfate transport system, periplasmic component  ali follow..  10  1..MSSNSLAGIVKLALVVGSLQLGSIGLALADTTILN------SYDPTRELYKEFNAAFAEKETVTIQTSHGGSGKQARSVIDGLEADVVTLALEADIDAIAKESGKIPADWKSRFENNS---VFLVRKGNAIKDWGDLVR--EDVQVITPNPKTSGGARWNFLAAWAWARAANNG-VPVLDTGARGATTTFVQRGLGDVLLAWENEAYLSLEELGPDNFDIVTPSISIKAEPPVALVDGNVDSKGTRKVAEAYLDY-------SDVGQKIAAKH---YYRPFKPE....................................................... 295
12 -13.000[R] COG2107 Predicted periplasmic solute-binding protein  ali follow..  9  2.................................KIRVAHTPDADDA-------FMFYAMTHDTWLEIEHVIED--ETLNRKAFNAEYEVTAISAHAYALLDDKY---RILSAGASVGDGYGPVVVAKSE-----------ISLDGKRIAVPGRYTTANLLL-KLAVEDFEPVEMP----------FDRIIQAVLDEEVDAGLLIHEGQITYADYGLKCVLDLWDWWSE-PLPLGLNAIRRDLSVEVQEEFLRAM---RESIAFAIENPDEAIEYAMKYSRGLDRERAKRFAMMYVNDYTYNMPESVDA................................. 246
13 -12.600[P] COG1840 ABC-type Fe3+ transport system, periplasmic component  ali follow..  14  12QTQTMEEIMRLTIISSLLLAGTTLLGVPAHAAGDLNL-------CAADVVICEQMKGDFEKTHDIKVNMVRMSSYAKIRAEARNPKTDLWWAGTGDPHLQAASENLTLEYKSKMLDQLQDYNTDIFKKKGYKEKCWADLLAPELKGEIQIANPNSGTAYTALASLVQIMGEDQAFDYLKKLYTKSGSAPVKAAARGETAVGIVFMHDAVAQTAEG----FPVKSVAPCE-EIGSMSIVKGARNLENAKTWYDWALQ..................................................................................... 295
14 -12.300[P] COG0725 ABC-type molybdate transport system, periplasmic component  ali follow..  12  1.MAHSWLRLVAGATLSFVIAGHALADE-----GKITVFA-----AASLTNAMQDIAAEYKKEKNVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAADKK---AVDTTTRETLLGNSLVVVAPKASEIDNKTDWIRLLNGGRLAVGDPQHVPAGIYAKEAL-QKLGAWQTLEPKLAPGEDVRGALALVERNEAPLGIVY--------GSDAVASKGVNVVATFPEDSHKKVEYPIAIVEGHKNATVSAFYDY------KGPQASAIFKRYGFT............................................................... 255
15 -12.300[H] COG4143 ABC-type thiamine transport system, periplasmic component  ali follow..  11  1..........MLKKYLPLLLLCAAPAFAKPV-----LTVYTYDSFAADWGPGPAVKKAFEADCNCELKLVALEDGVSLLNRLRMEGADVVLGLDNNLLEAATQTKLFAKSGVANEAVKVPGGWAFVYDKSNPPKSLKELVESDQKWRVIYQDPRTSTPGLGLLLWMRKVYGDNAPQAWQKLVTKGWSEAYGLFLKGESDLVLSYTTSPAYHIIEEK--KDNYAAANFSE-QVEVAARTVASKQPELAEKFLKFMVS..................................................................................... 268
16 -12.000[R] COG1427 Predicted periplasmic solute-binding protein  ali follow..  11  2.................................TITVGEIKYTNAF-------PFFYYVDRNKLLEKDCHFLIQTATLNREMKAGRIQVGPISSFAYAENVDEF---VLMPNLSVSANGPVGSIFLYTK----RPLEEL----EGSRIALTTTSATSVHLL-KILLKQYVGVNVTYDEM--------DPSFDEMMQDHDGCLLDEAIVTSWREEVETYRYDLGELWKE-SMTFAVFAVRKDAIARQRAILEELYTAFVLSKEKNRKEQYASMIGHIQKGMGGTTAFWNHYFSNLVYDFHTQQQK..................................... 251
17 -11.300[Q] COG4663 TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component  ali follow..  13  1MDRRSFIKHASIGGLGAAAASALAAPAIAQTNPKVTWRLTSSKSLDTIYGGAEVLSKYVSEATDGNFQIQVFAA-LQAADAAAAGTVEACHTVAYYYWGKDPTWALGMNAWHYHGGGIDLFNEFLGGWFRKEIKTVADM----KGLKMRVGGFAGK---------VMERLGVVPQQL-------AGGDIYPALEKGTID-AAEWVGPYDDEKLGFYKVAPYYYYPGWWEGGPTVHAMFNKALPKAYQSLLRTACQATDANMLQKDYLNPSAIKRLVAAGLSPFSPEILSACFDESNKVYAEMEASNAPFKKI............................. 333
18 -10.600[R] COG4588 Accessory colonization factor AcfC, contains ABC-type periplasmic domain  ali follow..  12  1..MKKIITLFGACALA-----------FSMANADVNL------GPGGPHTALKDIANKYSEKTGVKVNVNFGPQ-ATWFEKAKKDADILFGASDQSALAIASDFGKDFNVSKIKP---YFREAIILTQKGNPIKGLKDLANKK--VPEGAGKSNTSGTGVWEDMIGRTQDIKTIQNFRNVAFVPNSGSARKLFAQDQADAWITWIDWSKSNPDI------TAVAIEKDLVVYRTFNVIAKEGASKETQDFIAYLSS---------KEAKEIFKKYGWRE.............................................................. 250
19 -9.090[S] COG3181 Uncharacterized protein conserved in bacteria  ali follow..  8  1..MKILNALLGAATAVSLFAASASAQTYPERTITMVVPFSAGGPTDTVARL---VAESMSKDLGQQIIVENVGGAGGTLGRVAQADPDLHHIGMATSATLYRKLAYDTLNAFEYVGLVTEVPMTIVARKDFEPTDLKGLIEHVKANTVTVANAGIGAASHLCGMMFMSAIETP---LTTVPYKGT-GPAMTDLLGGQVDIMCDQTTNTTKQIQGGTIKAYAVTSPQRLKIFPDLPTAEEAGLPAEVTDRLSKSLQKALKDENVVARFGELGTEPSSEADATPAAESEIGRWKPVIEAAGQYAD...................................... 325
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 3 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Erlandsen H, Godzik A. HEPN: a common domain in bacterial drug resistance and human neurodegenerative proteins. Trends Biochem Sci. 2003 May;28(5):224-6. Review.