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Query: [L] COG3293 Transposase and inactivated derivatives, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSRYDLSDFEWHVIKPLLPNKPRGVPRVDDRRVMNGIFWVLRSGAPWRDLPERYGPRTTCYNRFVRWRKASVWDRLMDAITAVHDGDIQMIDSTSVRAHQQAATAKKGGQITVSVTRGGLTTKIHVVVDAQGLPIRLGLTAGQAHDSQIADQLLNHLSPRTIVLADKAYDADRIRSLIEGQGATPNIPPKSNRRWKPCFSKRLYRERNLIERFFSKLKHFRRIATRYDKLAANFLAMVQLASMRLWLRAYESTALast
1 -115.000[L] COG3293 Transposase and inactivated derivatives  ali  100  1MSRYDLSDFEWHVIKPLLPNKPRGVPRVDDRRVMNGIFWVLRSGAPWRDLPERYGPRTTCYNRFVRWRKASVWDRLMDAITAVHDGDIQMIDSTSVRAHQQAATAKKGGQITVSVTRGGLTTKIHVVVDAQGLPIRLGLTAGQAHDSQIADQLLNHLSPRTIVLADKAYDADRIRSLIEGQGATPNIPPKSNRRWKPCFSKRLYRERNLIERFFSKLKHFRRIATRYDKLAANFLAMVQLASMRLWLRAYESTA 254
2 -20.100[L] COG5558 Transposase  ali follow..  13  30.EKEKYPYTEWERKREVVQKRVGRPKKVDLEKRVMLFLFARLMDKSNRDIEELLELFEPLYKTIERLYSDEEVRMALHNLFILLLREEGVS-GDFSGDGTGYSLTITKHYRSNPKRKGKDFRYVFRIIDDTGMYVGFGYSDRSEKDAFEKALGMLKSMKVNSISLDKYYSSRKTLRLFDAETAVYVIPKRNLARIGFDWLRVIYFKRNLSEAGFSADKRIRQRREDRREMALFAVGLWHNVFAVRVVR...... 322
3 -15.100[L] COG3385 FOG: Transposase and inactivated derivatives  ali follow..  15  1MRF---TPSIFAQLLKAIDRRSAYDKCFTSWDHLVALIYAQLSATT-RGLEASFNA-RSTLSDANRRRPVAVFAETFALLAGQLDRQTRREGTKMLRLIDSTPIPLGKLYDWAKSNGRIRGMKLHVVYDKADCPGILDITDANVNDAQIGRTI--TIEKGATYVFDKGYCHYGWWTAIAEAGASFVTRPKTNMGLALVAERQLYKDRWQIELLFRWIKQHLKIRKFLGNNDNAIRLQIFAAMIAYALLRIAARL 335
4 -13.700[L] KOG4585 Predicted transposase  ali follow..  13  273FDILRMHQSTFRTLCKILSEQLEESCNIYLEESVAMFIEMVAQDLTVRVIAERYQSLETVKRKLDEVLSRDDVTGISPFLVNDKRYMPYFIDCIGALDGTHVSVRPPSGDVERYRGRKSEATMNILAVCNFSMKFNIAYVGGRAHDCATHEASFPHPPAGKYYLVDSGYPTRSGYLGRTRYHLELFNRGGPPTNSRELFNRRHSSLRSVIERTFGVWKKWRILDRKHPKYEVKKWIKIVTSTMAL......... 545
5 -13.500[L] COG3039 Transposase and inactivated derivatives, IS5 family  ali follow..  14  38..........LNLVTSDLRRTETGRQGLPSEAVLRCALLKQYRQLSYEELAFHLED-SASFRAFISAIRADTWEAVNKMLLASARQERLESGRVVRVDSTVTAALIHEPSDS-GSRDVDYGHKLNLTTGRSGLILDLVIEAGNPADSERLLPLLERHIAPRQAAADGGYASRENLRQAKAWGVRDMAFHKKSGLRIEDMVRKLRNFRAGIEAGISCLKRTYGLARCTWRGLDHFKTYVWSSVVAYNLALFARL. 441
6 -8.210[R] COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA  ali follow..  16  1MKTGPLNESELEWLDDILTKYNTDHAILDVAE-LDGLLTAVLSS-QW--LVAVWGGADY-----PRWASEKEMTRFMNLAFQHMAD........................................................................................................................................................................ 85
7 -8.200[L] COG2818 3-methyladenine DNA glycosylase  ali follow..  20  40....AYHDNEW------------GVPVADDFRLFEKILEGFQSGLSWLTILRKRENFRAAFDGFNFHRIATYDESDVERLLADKGIVRHRGKIVSVINNAGRAIELIEEKGSLAA........................................................................................................................................... 139
8 -7.640[L] COG3666 Transposase and inactivated derivatives  ali follow..  15  28......ENHVARVVNDMVESKGGGRPAYHPKMMTKILLYGYTQKWF-RAIAKA-PDFRTI-NRFRSERLKPLMDTLFSALTHLLIKEGYVDGSSYFLDGTKIEANANKYTKDDHMKNGQLKAGYNWQIGTQDQFILFYTVHPNPTDTRCLLPHVEALKESKTLIADAGYGSESNYVAMADELFETLIPAKQHQKLKSEEGRTLYQKR-DVESVFGHVKQNLGFRRLHLRGKESVHIELGLVALAHNLRKRAT.. 528
9 -7.240[K] KOG2473 RNA polymerase III transcription factor (TF)IIIC subunit  ali follow..  11  243....ALFEERWTRIVQRLLDKGLTCTHHMLNRFLLRAAYYFSGG-PFLRFPRKDPEFQRMEFRVPPWFSEALLDNLRLRVAVRFVSVFPEPGFEDVFKSIQEEFERSEKTRIQKDALQPSQRNHQETTKD............................................................................................................................ 444
10 -6.670[B] KOG2748 Uncharacterized conserved protein, contains chromo domain  ali follow..  11  1MELPAVGEHVFA-VESIE-----------KKRIRKGVEYLVK----WRGWSPKYNTWERLLIAFQNRERQ........................................................................................................................................................................................ 63
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.