Scheduled maintenance will begin on May 30th, 2025. Server will be temporarily unavailable — learn more.
current user: public
If you have questions about the server, please let us know.

Query: [M] COG3307 Lipid A core - O-antigen ligase and related enzymes, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410
# Score Template Links and tools%idFirst MTTLSPAIPVNRRSEMLCSIAALLLGISMPTNNQLMSVSLVLIIISLIINRKSLDFKPLLTSPLVYLPAAMFVLLALSLLYQNNSYGPDMVGKYKKLLYILPLALFFMNQPRLIKLFCTGFLVANAVILAGSLAVGVLHIPLSGVDPTNPTIFKLQITQNFFMALAALLWLVLAFQHQGWKRWGYSVLVVAASYSILFLVLGRTGYVALIVGLGVWLFFSLGNRQRLTLVVLGALAFAALIFIPNKATDRIVQGVDEIKVCMAASATDAADACNSSMGQRSAFVVEAARLIKESPILGHGAGGFYYENKEVDYKVNNPHNQYLLETIQSGVIGLFLFLAWVICCYRVIWQQTPALRNVLLAVLTSYMACNFFNSFLLDSSEGHLFMIFVAVLAGYSVSGSQSIAGKRLPTLast
1 -103.000[M] COG3307 Lipid A core - O-antigen ligase and related enzymes  ali  100  1MTTLSPAIPVNRRSEMLCSIAALLLGISMPTNNQLMSVSLVLIIISLIINRKSLDFKPLLTSPLVYLPAAMFVLLALSLLYQNNSYGPDMVGKYKKLLYILPLALFFMNQPRLIKLFCTGFLVANAVILAGSLAVGVLHIPLSGVDPTNPTIFKLQITQNFFMALAALLWLVLAFQHQGWKRWGYSVLVVAASYSILFLVLGRTGYVALIVGLGVWLFFSLGNRQRLTLVVLGALAFAALIFIPNKATDRIVQGVDEIKVCMAASATDAADACNSSMGQRSAFVVEAARLIKESPILGHGAGGFYYENKEVDYKVNNPHNQYLLETIQSGVIGLFLFLAWVICCYRVIWQQTPALRNVLLAVLTSYMACNFFNSFLLDSSEGHLFMIFVAVLAGYSVSGSQSIAGKRLPT 410
2 -10.600[D] COG0772 Bacterial cell division membrane protein  ali follow..  10  23................................................................LLLGVLALMGFGLVVMYSASGQSLAMMDRQAMRMAMALIIMVILAPPRTYESAAPILFFCGVILLVCVLLFGEISKGAQRWLDLGFVRFQPSELLKLAVPLMVARYIGKHALPPSFKTLFASLVMVFVPTILIAKQPDLGTSILIAASGIFVIFLAGISWKLITAAAVAIGAFVPVLLMHEYQKTRVRTLFD--------------ESDPLGAGYHII---QSKIAIGSGGLSGKGWLHGTQSQLEFLPE---RHTDFIFAVIEWGMIGLSLYLFIIGRGLYLASHAQTSFGRMMAGSIVLSFFVYVFVNI-YGGTSMVTLMAGFGILMSIHTHRKAFSKT..... 372
3 -9.440[S] COG4713 Predicted membrane protein  ali follow..  8  118.................................................................IVYIPQSIGINLAKIFRASALYMMYFGRIANLICWTIIVFFSVKLIPFKKNLMAFLALTPMNLYQAASLSA------------------------TNSMAFLSIALVLRYAFGEEEAKLTKRQIVTMIIAFTLLAFSKRIYFVMCILFFIIPIKKFNSKKDYIGTFVIMLGACLMSLV-----------------SVISKILAIKVSAGSYTPGQMEF-------VLSHPI---------TYIHILLRTFHFKMSFYAISFI--GVFGFYGVALVLIALFEHTLIEKNKDRIIMFIVFIINVGLIMSALYVSWTPKAAYFIPIIPLLGCFIGVKANKSRNV.... 425
4 -8.850[S] COG4292 Predicted membrane protein  ali follow..  9  77...............................KASFPELFFDLVFVFALIQLSESLSDDFSLGIAAEAVLFIFALWWVTTWVMDLLDTEIEPVRLLLFTLMFFGIVMAIALPEAFKGMGLLFAVAYSAMQVSRSLFALYAFRRGDPASFMTF-----FRITAWLTISSTFWITGGLSEPHLRVVLWIVALVVEYTGPTVRYAERSALFVIIALILTIGKHTFSNLETEGTPWVLCFSFLTTVLMWWIYFHDGQQRAAD----------KAEDTSKPQTTAQYLFTYGHLPIVGGIIFTAVGEDFS------LAHPYQLGTYNFALAQL-----GPILFLAGTMWMKRVSSRVLPYSHVFGISLLTASFTLVPFVANFAIQALTGVILLVVAVWEYVALKHLRRSAA..... 451
5 -7.860[O] COG4346 Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase  ali follow..  8  178.........................................................................IIALGMLIEDKPFYWRIPGIIEHALIVIIVTLVA---YKITKSYLASSIAATFAALDPLLF-----------------ATGIVAMLDIHVAFFIALFMLFLALDR----------IRLSGIALGLAAATKLSGAFAFPILWFKILKEKDLKEYLISGLVLPMVSFLIPEITIIKAIGFIPWLEEFIASFSWHLSFKGEHPSEAP------W-----FVSLKPFP-------------FDPDVYAVTDPIL-------ISMIVFVFAVPYVSLRRKGLSEIFWMFWSAFFALQYILGGKTQFIFYATPLIPPGAVALGVISYEIIKWEYFERS..... 456
6 -7.510[RT] KOG0748 Predicted membrane proteins, contain hemolysin III domain  ali follow..  14  1..................................................................................................................................................................................................................................................MGDEAEIKEHLKPQASSETMDKKHNVKGKRLWQKVKYQLVEFHSLPAYLRDNEYIIGHY---EWPIKQILLSIFTIHNETLNVWTH--LIGFFLFLALTIYTA................................................................. 100
7 -7.360[BK] KOG3001 Dosage compensation regulatory complex/histone acetyltransferase complex, subunit MSL-3/MRG15/EAF3, and related CHROMO domain-containing proteins  ali follow..  5  538...................................................................................................................................................................................................................................................NVSKPQKLARSPARISPHIKDGEKDKHREKHPNSSPRTYKWSFQLNELDN---------NSTERISFLQEKLQEIRKYYMSLKSEVATID------------KRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVL........................... 660
8 -7.240[P] COG3303 Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit  ali follow..  13  3....................................................................................................................................................................................................IYL---RFVWILIIILNFLLNLFITTNGVIIVNAFKKSLIVAASFASLSLFNSATAELVYKPLEQPVEPAKPDLKIESVNEKNQYNSWRSTAN-DEENPRLGYAFAK--------EYNAPRGHFYAVT...................................................................................... 138
9 -6.720[O] COG4745 Predicted membrane-bound mannosyltransferase  ali follow..  10  1MRRSRDDSSPRVAAAVVAVTAAALLARLWALGWRVAH-ARVADWTLQYMDLGAWQYRPIIHGP-----FLPHVNGVVFDVFGATDFTMRLVVAVVGGLLP-LTAWLYRTRLSDVEVGALAVLLAANPVVLY---------------------YSRFMRNDLLLAGFMFTAVGLFVRFLDTHRARYLYASAVPF--ALAFTTKENSLLYPLCWLGALALVTDDRMAVAGATDTSRLAVVRRAAARIRHRAWRAKAALAGSALTAAVIVVSFYAPKPDLYRLFEQPGRAPAVLEAATIGTY---DLWASTSTVAHSYVAFLSHDLSVLVACGTVVSVAAVVGYLANRYATETPRPLVSFAFYWGVFSVLGYPAVVDIWTAVNALVPLAIPAAVGVGAVVRYGRRGAAAGDTA 387
10 -6.670[O] KOG2292 Oligosaccharyltransferase, STT3 subunit  ali follow..  7  94...............MITSGGIHWLLHVLNIPVHIRDICGLTSISTYLLT------KELWSAGAGLFAASFIAIVPGYISRSVAGSYDNEGIAIFALQFTYFLWVRSVKTGSVFWSAAAALSYFYMVSA-----------------------WGGYVFIINLIPLHVFVLLIMGRYSPRLLTSYSTFYILGLLFSMQIEHMAALGVFVLLMAVATLRHLQSEFRKLFIVGGLLVGVGVFVAVVVLTMLGVVAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTTWFSFFFDLHILVCAFPVGVWYCIKQINDERV------------------FVVLYAISAVYFAGVMVRLMLTLTPVVCMLAGVAFSGLLDVF................................... 430
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 0   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Schwarzenbacher R, Godzik A, Jaroszewski L. The JCSG MR pipeline: optimized alignments, multiple models and parallel searches. Acta Crystallogr D Biol Crystallogr. 2008 Jan;64(Pt 1):133-40. Epub 2007 Dec 5.