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Query: [Q] COG3321 Polyketide synthase modules and related proteins, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDAQVAVYQAALAVAGVEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSVFAVQVALATTMEQTYGVRPGAVIGHSMGESAAAVVAGALSLEDAARVICRRSKLMNRVAGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVMAREVAVDVASHSSQVDPILDDLAAALADIAPMTPKVPYYSATLFDPRELPVCNGAYWVDNLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMALAAAVEVFGEAAEVRAIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDDCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQLGAAFAGLATAHTAEAESGTVLAEVALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDPVVSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFVGVVTAVGEGVTGHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQAITAATAHATAWYGLNDLAGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITGGLGGLGLFFASKLAEAGCGRIVLTARSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGYIPILGAPWLPDLVRRSPWAEMLast
1 -343.000[Q] COG3321 Polyketide synthase modules and related proteins  ali  100  1METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDAQVAVYQAALAVAGVEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSVFAVQVALATTMEQTYGVRPGAVIGHSMGESAAAVVAGALSLEDAARVICRRSKLMNRVAGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVMAREVAVDVASHSSQVDPILDDLAAALADIAPMTPKVPYYSATLFDPRELPVCNGAYWVDNLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMALAAAVEVFGEAAEVRAIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDDCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQLGAAFAGLATAHTAEAESGTVLAEVALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDPVVSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFVGVVTAVGEGVTGHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQAITAATAHATAWYGLNDLAGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITGGLGGLGLFFASKLAEAGCGRIVLTARSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGYIPILGAPWLPDLVRRSPWAEM 1999
2 -39.500[IQ] KOG1394 3-oxoacyl-(acyl-carrier-protein) synthase (I and II)  ali follow..  24  57.TDPKKRVVITGMGLVSVFGN-DVDAYYEKLLSGESGISLI--DRFDASKF------------TRFGG---QIRGFSSEGY-IDGKNERRLDDCLKYCIVAGKKALESANLGGDKLNTRKAGVLVGTFSEGVQNLIEKGHRRISPFFIPYAITNMGSALLAIDLGLMGPNYSISTACATSNYCFYAAANHIRRGEADMMIAGGTEAAIIPIGLGGFVACRALSPQTASRPWDKARDGFVMGEGAGVLVMESLEHAMKRGAPIVAEYLGGAVNCDAHHMTDPRADGLGVSSCIERCLEDAGVSPEEVNYINAHATSTLAGDLAEINAIKKVFKSTSGIKINATKSMIGHCLGAAGGLEAIATVKAINTGWLHPSINQFNPEQAVDFD----TVPNEKKQHEV------DVAISNSFGFGGHNSVVAFSA................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 470
3 -38.700[I] COG0331 (acyl-carrier-protein) S-malonyltransferase  ali follow..  23  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVL----GYDLRRLIDSDLKLNQTSYTQPAILTSSIAIYRVL-GLHHVKPDMVAGLSLGEYSALVASGALSFEDTLSLVAKRGRLMEEAQGSGKMVAVNTDVQVIEEVCQIAAKHGVAPANYNTPSQIVIGGQTDAVNVAVELLKERGVRLIPLNVSGPFHTALLEPASRLLAKELERYNFSDFKIPLVGNTEANIMEKDRI-PELLARQVMEPVRFYDSVATLVESGITQFIEVGPGKVLTGFVKKIDKNLLCTSV---------ENMVSLRLFLDREDIHG......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 311
4 -37.400[IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase  ali follow..  26  2...SKRRVVVTGLGMLSPVGN-TVESTWKALLAGQSGISLI--DHFDTSAY------------TKFAG---LVKDFNCEDI-ISRKEQRKMDAFIQYGIVAGVQAMQDSGLEITEENATRIGAAIGSIEENHTSLMNGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISIATACTSGVHNIGHAARIIAYGDADVMVAGGAEKASTPLGVGGFGAARALSPQAASRPWDKERDGFVLGDGAGMLVLEEYEHAKKRGAKIYAELVGFGMSSDAYHMTSPPENGAGAALAMANALRDAGIEASQIGYVNAHGTSTPAGDKAEAQAVKTIFGEASRVLVSSTKSMTGHLLGAAGAVESIYSILALRDQAVPPTINLDNPDEGCDLD----FVPHEARQ-----VSGMEYTLCNSFGFGGTNGSLIFKK................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 412
5 -30.900[I] KOG2926 Malonyl-CoA:ACP transacylase  ali follow..  18  2.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SAILFPGQGVDWKTWMQPYLE-NNIVQNTLKEAENVT----EIEIRKYIVEAEAQPITTIAQPAILACSIALLRAF-PPFTKKFRFYVGHSLGEYSAFVASQTLSFSSALKLVQARAKAMSYASNPTSMLAILTSRFPTDNFLNTQKYRLIDIANVNSDRQIVLSGDKKELESITSTLSELVLRSNWLDVSGAFHSRYMLPARDSLKNALGETEFNKRFLPIISNVTAELYPADEEDRRQLLLQCFRPVLFKNCLKTVKSKGANLFYAYGPGTTMQSIAKQNGISTKS...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 316
6 -17.300[CR] KOG1197 Predicted quinone oxidoreductase  ali follow..  25  4...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GIRVYEHGGPEVLKWEDVEVGEPKEGEIRVKNKAIGLNFIDVYFRKGVYKPAS--PFTPGMEAVGEVVAVGSGLTGRMIGDLVAAGNPMGAYAEEQILPADKVVPVPSSIDPIVAASIMLKGMTAQFLLRRCFKVEPGHTILVHAAAGGVGSLLCQWANALGATVIGTVSTNEKAAQAKEDGCHHVIMYKNEDFVSRVNDITSGKGVNVVYDSVGKDTFKGSLACLKSRGYMVSFGQSSGSPDPIPLSDLAPKSLFLTRPSMMHYN-ETRDELLECAGEVFANVTSGILKARVNHKYPLSRVADAHADLENRITSGSVVL.................................................................................................................................................................................................................................................................... 322
7 -14.900[R] COG0300 Short-chain dehydrogenases of various substrate specificities  ali follow..  16  3.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KKTIFITGASSGLGRQLAIDFSWEET-VLCLFARS--QERLENVQRIVVENGGEAHIYPVDLADPQSIDRSFAEAISAVGVVDVLINNAGYGVFEPFCDSQMDENERMFRVNVFGLMRATAAVREQGSGHIINIASQAGKIATAKSAIYSATKGFTNSLRMELKGTGIHVSAVNPGP-QADKEGAYTSKVQRIMLDPEDVSEKIVQLTKKPKRELNL..................... 230
8 -13.600[M] COG3967 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)  ali follow..  16  4................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TNNTVLITGGSAGIGLELAKRLLELGN-EVIICGRS------EARLAEAKQQLPNIHTKQCDVADRSQREALYEWALKEYPNLNVLVNNAGIQKEIDFKKGTEEVDGDEIELNFQAPVHLSALLMKQPEAAIVQVTSGLAFNPLAVYPVYCATKAALLTLRHHVRDTSVEVIEMAPPMVDTGQKSRDKQGLTYRGISSEEYVQYFLDGLKEGKQEITN..................... 226
9 -13.400[CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases  ali follow..  17  3...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ALLLEQQDGKTLASVQTLDESRLPEGDVTVDVHWSSLNYKDALAITGKGKIIRNFPMIPGIDFAGTVRTSE--DPRFHAGQEVLLTGWGGGLAEQARVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALGVRPQDGEIVVTGASGGVGSTAVALLHKLGYQVVAVSGRESTHEYLKSLGASRILPRDEFAESRPL----EKQVWAGAIDTVGDKVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPERRAQAWQRLVADLP----ESFYTQAAKEISLSEAPNFAEAIINNQIQGRTLVKVN................................................................................................................................................................................................................................................................. 324
10 -13.100[I] KOG1200 Mitochondrial/plastidial beta-ketoacyl-ACP reductase  ali follow..  18  76.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SPVVVITGASRGIGKAIALALGKAGCK--VLVNYARSAKEAEEVAKQIEEYGGQAITFGGDVSKATDVDAMMKTALDKWGTIDVVVNNAGITRDTLLIRMKQSQWDEVIALNLTGVFLCTQ-------GRIINISSVVGLIGNIGQANYAAAKGFSKTAAREGASRNINVNVVCPG-FIASDMTAELGEDMEKKILGTIPLGRYGKAEEVAGLVEFLALSPAASYITG.......... 297
11 -13.000[KC] KOG0025 Zn2+-binding dehydrogenase (nuclear receptor binding factor-1)  ali follow..  21  42................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KPSADQVLVQWIAAPINPADLNQIQGVYPVKPALPAVGGNEGFGKVISVGSNVSSIKVGDHVIPDRSGGTWRELGLHQENDLFPIDNTLSMEYAATFQVNPPTAYRMLKDFIDLKKGDTVAQNGANSAVGKHVIQICRILGIKTVNVVRSRDNLEELVKE-LKDLGADEVITQEELYSRKKKFPGVKLALNCVGGRSSLFLASLLDHGGCMVTYGGMSKQPVDCPTGPLIFKDISLRGFWMSRDIQKSPEKRHEMYQELAGWMKSGEIKKQEIVKNRLEDHAKALDTALSKFDKKQFFV.................................................................................................................................................................................................................................................................... 342
12 -12.400[CR] KOG1198 Zinc-binding oxidoreductase  ali follow..  23  5...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................YVVHDEISGFDQLKPEEYEVPQKNPGEVLVKLKAASLNYRDLIITKGLYPLPLQLPVVPGSDGAGIIEKVGEDVEGFEKGDSVVGGTRDGCFQKYAVLPAHALVHAPKNLSFEEIATLPCAAVTAWNGLFGSHQVKPGNNVLVL-GTGGVSTFALQFALAAGANVTVTSSSDEKLEFAKKLGATHTINYKKTQWASPALKMTNGVGYHHVIEVGGEKTLPQSIACLAKDGMISMIGFVA--EGTTPNLTSIIGQILNRNANIRGIFVGS----VSMFRDMVACIEAKDIHPVVDKVFPFDQLKEAYEYQWSQAHIGKVVLKID................................................................................................................................................................................................................................................................. 346
13 -12.300[R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity  ali follow..  16  7.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GKIAVITGAASGIGLATTEALLEQGAT-VVMVDWN-----EKALNDLAAKLGERAIPQVTNLLDADSCNAMIPEILGKVDHIDILYCNAGTYIGGDLTETTPEAIDKMLNLNVNAVMKNVQAVVPHMSEDIIVTCSIAGHFPTYWEPVYSGSKSFVQGMRRQMIPHGVRVAQVSPGP............................................................. 185
14 -11.800[Q] KOG1210 Predicted 3-ketosphinganine reductase  ali follow..  16  31................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PGAHVVVTGGSSGIGKCIAIECYKQGA-FITLVARN--EDKLLQAKKEIEMHSIVVLCISVDVSDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVKERRVGRIVFVSSQAGQLGLFGFTAYSASKGLAEALQMEVKPYNVYITVAYPPD-RTKPLETRLISETTSVCKPEQVAKQIVKDAIQGNFNSSL..................... 267
15 -11.700[Q] KOG1204 Predicted dehydrogenase  ali follow..  14  4...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VILITGASRGIGLQLVKTVIEEDDE-CIVYGVARTEAGLQSLQREYG--ADKFVYRVLDITDRSRMEALVEEIRQKHGKLDGIVANAGMLEPQSNSEHDIKQWERLFDVNFFSIVSLPLLKSSPFVGNIVFVSSGASVKPYNGWSAYGCSKAALNDIASEEPSDKVRAVCIAPGV--DTQMQKDIRETLGPQGMTPKALERFTQLYKTSS.......................... 223
16 -11.500[Z] COG5245 Dynein, heavy chain  ali follow..  10 1228....................VKTYDLVWRSIKNLWEDVQRTFETPWDLANFLRRADELPRKQFEMYKSLFSQVNMLTSVNKILVELKDGALKPRH-------WNMIFRD------------------IGKRQIQKNLLDKLEFSLKDVMVLNLTLNEILLTKIIERAQKEFVIEKSLNRIKKFWKEAQYEVIEHSSGLKLVREWDVLEQ-ACKEDLEELVSMKASNYYKIFEQDCLDLESKLTKLSEIQVNWVEVQFYWLDLYGILGENL---------------DIQNFLPLETSKFKSLTSEYKMITTRAFQLDTTIEVIHIPNFDTT--------LKLTIDSLKMIKSS------LSTFLERQRRQFP-RFYF------LGNDDLLKIIGSGKHHDQVSKFMKKMFGSIESIIF---LEDFITGVRSVEGEVLNLNEKIELKDSIQAQEWLNILDTEIKLSVFTQFRDIEVVVSKYIFQAILAQVMWTELVEKCLQTNQFSKYWKEVDMKIKGLLDKLNKKKIEALLVEYLHFNNVITKEEARLLWAKVQKFYQKND-----TLDDLNSVFISQSGYLLQEYIGIPERL----IYTPLLLIGFATLTDSLHQKYGGCFFGPAGKAFGQNLGRVVV-VFNCDDSFDYQVL-SRLLVGITQIGAWGCFD-EFNRLDEKVLSAVSANIQQGLQVGKSHITLLEEETPLS------PHTAVFIT-LNPGYNGRS----ELPENLKKSFREFSMKSPQSGTIAEMI--LQIMGFEDSKSLASKI---HFLELLSSKCSSMNHYHFGLRTLKGVLRNCSPLISEFGEGEKTVVESLK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 1999
17 -11.300[R] KOG0725 Reductases with broad range of substrate specificities  ali follow..  17  3...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................CALVIGATSTLGKAVVRRLAFTGYK-VAAAADC--PNSVGKVAEDNIKVGGDVTAFSLDVANAEHRKELITKVAEKLGGLDTLIIVPPQNEVGEIIETSGEDFDKLFANNLTTPFRLSQAAMSTLAKSIIYLTSCFGFTPSIDMGLYSVASSSVKSVAQSAAKQGVRVNSVVSG.............................................................. 182
18 -11.200[Q] KOG1201 Hydroxysteroid 17-beta dehydrogenase 11  ali follow..  12  51................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AGEVAVVTGAGHGLGRAISLELAKKGC-HIAVVDIN--VSGAEDTVKQIQDIKVRAKAYKANVTNYDDLVELNSKVVEEMGPVTVLVNNAGVMMHRNMFNPDPADVQLMINVNLTSHFWTKLVMKELRKGFIVTISSLAGVFPLPYSATYTTTKAHMRTLRMELDLENQKDIHVT-NSDVTQLTHTIGFGDVYPLFTGEEVAQRIVAGMVRGEAEITV..................... 282
19 -11.100[Q] KOG1205 Predicted dehydrogenase  ali follow..  17  47.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GKVVIITGSSSGIGEHLAYEYARRGA-YLTLVARR--EDRLQVVADRCRKLGSDVAVVRGDVSVIKDCKRFVQETISRFGRLDHLVNNAGIAEAKFFEDYSESDVLPIVNTNFWGPVYATHFAIPH--GKIIAVASPAGWSGVPRMSIYAASKAAMINFYETLRIEEVGVTIVFPGL-AESLLQKQDWSQVVTIESAAECAKAVVNGICRGKTFVAE..................... 278
20 -10.900[O] KOG3525 Subtilisin-like proprotein convertase  ali follow..  16  160....................FPDPKDQWYLHGGAVGGYDMNVRQAWLQ--------GYAGRNVS---SILDD---------GI---QRDHPDLAANYDPLASTDINDHDDDPTPQNNGDNK---------------------------------------------HG------TRCAGEVAAL-------GNNQCGVGVAGGVRMLDGAVSDSVEAASLSLNQD--SASWGPEDDGKT--DGPGPLAREAFYRGIKNGGNIFVWASGNGCSADGYTTSVYT----------------------SISSATYDNHRPWYLEE--PSSIATTYSSADFRQPAIVTVDVGTSASAPLAAGIIALAL--------------EANPELTWRDMQHLVLRTANWWSRNG------VGRNKFGYGLIDGGALVNMAPEQHICTYEYRLANPNPRPIVGRFQLNFTLDVNGCESGTPVLYLEHVQVH-------TVRYL---KRGDLKLTLFSPSGTRSVLLPP........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 570
21 -10.800[IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)  ali follow..  20  6.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GKTALITGASQGIGEGIARVFARHGANLILL----DISDEIEKLADELGGRGHRCTAVKADVRDFASVQAAVARAKETEGRIDILVNNAGVCRLGNFLDMSEEDRDFHIDINIKGVWNVTKAVLPEMIKRIVMMSSVTGMVADPGETAYALSKAAIKSLAVEYAQSGIRVNAICPG.............................................................. 186
22 -10.700[KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family  ali follow..  14  695............................................................................................PQQ---IQATLRSYQTEGVH-ERLRKMHLN---GILADD-----------------MGLGKTLQA--IIAVTKGSGCSLIV---CPTSLVY---------KEEFR----------FNPEFRTLVIDG---VPSQRRKQLTALAD----------VAITSYNLLQKDVELYKSFRFDYVVLDEAHH----IKNRTTRNA-------------KSVKMIQSDHRLILTGTPIELEELWSLFDFLMPGLLSSGNYMGNKADNMVALKKKVSPFI-LRRKDLPPVSEILY---HCHLTESQKELYQSYA----ASAKQELSRLVKQEGFERIHIHVLLTRLKQICCHPAIFAKDAPEPGD---------SAK----YDMLMDLLSSLVDSGHKTVVFSQYTKMLGIIKKDLESRFVYLDGSTKNRLDLVNQFNEDPSLL-----------VFLISLKAG---GTGLNLVGADTVI---------------------------------HYDM-------------WWNPAVENQAT-VHRIGQSRSVSSYKLVTIEEKITLQNRKKSLVKKVINSDDEVVSKLTWEEVLELLQ...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 1165
23 -10.200[Z] COG5022 Myosin heavy chain  ali follow..  11  69.................RSINSDADDLTDLSYLNEPSVLDALSTRYNQLQIY-----------TYSGIVLIAVNPFQPNLYTYSEKSRDELDPHLYAIAEDSYKCMNQEHKNQTIIISGESG--------------------------AGKTVSA----MRYFASVQALIQSTDSNFHEAPQLTAVENEILATNPIMEAF-GNSKTSRNDNS----------SRFGKYIQILFDGNATIIGAKIQTYLLERQPNQERNYHIFYQILAGSSSEKQGNCSTIEGVNDKEEFKATVDALKTVGIDNDTCECI--------------FSLLAAL------LHIGNIESKNENLINATSLLGLTKRKIKMASEGILKPLNEFQAVVA---DSVAKFLYASLFDWLVATINKALMYSADKSNQTAKSFIGVLD-----------------------GFEHFKKNSFEQFCINYANEKLQQEFYRH-------------------------VFKLEQEE-----------------------------YAAEGLNWSYID-SMIESRLGILSLLDE-ECRMPTNSDENWVSKLNDSKPEFKNSYQKSRF-----------------NKEFTIKHYALDVV---AEGFID-RDTI-----SDELLELFTNSDVPFVKDLVLFRLEQTAPPADTKK---IKTKPKSNTLGSMFKSSLVSLMSTINETN-YIRCIKPNEEKEAWKFDNVVSQLRGVLETIKISCAGFPSYYMLVPSAVRTTE-------LTFSKAILEKHADPTKYQIGKKIFFRSGVTPLLESARDKALKHA---AHLLYEAFAVNYYRTRFLLSRKRV............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 796
24 -10.100[I] KOG4087 Phospholipase A2  ali follow..  18  1..................................................................................................MTIIFKKLK-CGIPLRLMQGS------GLASRTKAQRT----GQFSTVIPSATTAAKAEGK-------QGPGVADD--CLES--GVH---RS---------------FQLLPKPHPLFSCYDCVSPDPPCRSSEKGPEEKVQNNGIGT----RLSSPKMAAEDV--IICDT-----------LQPCHVAMATVI-----DADRKTAKVQSV-AKGVG--FGESLEDKGF-------------SVRKN-GK-EAKAGL-NTVKMC--------PRMLHTQRRLQD---------KSPNLSIPNQNATVKAYQYKTSGL----QPSPYFLQELPPKSRGHPLDTPHLPQELPPGLPNNINIKTHRPHLAFRRIK......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 294
25 -10.100[I] KOG1014 17 beta-hydroxysteroid dehydrogenase type 3, HSD17B3  ali follow..  14  48.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GQWAVITGAGDGIGKAYSFELAKRGL-NVVLISRT--LEKLEAIATEIERTGRSVKIIQADFTKDDIYEHIKEKL--AGLEIGILVNNVGMLPNPSHFLNAPDEIQSLIHCNITSVVKMTQLIESRQKGLILNISSGIALFPWPLYSMYSASKAFVKALQEEYKAKEVIIQVLT--PYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETC....................... 266
26 -9.950[I] KOG1206 Peroxisomal multifunctional beta-oxidation protein and related enzymes  ali follow..  14  8.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KDRVVVITGAGGGLGKVYALAYASRG-----AKVVVNDLGGTLGGSGHNSKAADLVVDEIKKAGGIAVANYDSVNENGEKI------TAIKEFGRVDVLINNAGILRDVSFAKMTEREFASVVDVHLTGGYKLSRAASQKFGRIINTASPAGLFGNFGQANYSAAKMGLVGLAETLAKEGAKYNINVNSIAPLARSRMTENVLPPH-------ILKQLGPEKIVPLVLYLTHESTKVSNSIFELAAGFFGQLRWERSSGQIFNPDPKTYTPEAILNKWKEITDYRDKPFNKTQHPYQLSDYNDLITKAKKLPPNEQGSVKIKSLC---------------------NKVVVVTGAGGGLGKSHAIWFARYGAKVVV-----NDIKDPFSVVEEINKLYGEGTAIPDSHDVVTEAPLIIQTAISKFQRVDILVNNAGILRDKSFLKMKDEEWFAVLKVHLFSTFSLSKAVTKQKSGFIINTTSTSGIYGNFGQANYAAAKAFSKTIALEGAKRGIIVNVIAPHAETAMTKTIFSEKELSNHFDASQVSPLVVLLASEELQKYSGRRVIGQLF............. 549
27 -9.880[I] COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH)  ali follow..  16  8...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RILVTGVASSIAYGIAQAMHREGAE-LAFTYQN---DKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSM--SALLTLSYLGAERAIPNYNVMGLAKASLEAMANAMGPEGVRVNAISAGP............................................................. 191
28 -9.820[J] COG0532 Translation initiation factor 2 (IF-2; GTPase)  ali follow..  13  363....EVGMNVQDIAKSI--KREPAEIIKKLFMMGTMVNQNQSLDE--------------------------DTIELILMDYGVTPVKKVEEDKSDIERLFVEDGYLKEENMVE------RPAVVTIMGHVDHGKTTLLDR---ESRVTEGEAGGITQHIGAYQIKANGKKITLDTP--------HEAFTSMRARGASVT---DITILV-------------VAADDGVMPQTIEAINHSKAAGVPIIVINKIDKPGANPQRVTQELTEHGVFPVPENG-ISAKFNQNLDELLDTVLLVA-----EVQELKADPTVRAIGTVVEAR-LDQGKGAIATLLVQQGTLHVQDPIVVGNTYGRVRTMTNDLGRRI------KEAGPSTPIE----------------------LTGLSDVPQAGDHFAVFEDEKAARAAGEERAKRAQLIK----------RQNTRRVNLDNLFDTLKEGQTKSVNIIIKADVQGSA------------------EALAASLQKIEVEGV-----------KVDIVHSAVGA--------ISESDISLAAASNAIIIGFNVRPTGLAREQAAQEEDIRLHSIIYKVIEEVETAMRGML------DPEEIIGEAVGTIAGFMVIGKVARDASVRVI--REGVV-----DGAIASLKHFKDDVKE-VGNAQEGGLMVEDFND----VEIDD------TFEVYKMVEIERK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 944
29 -9.600[G] COG3459 Cellobiose phosphorylase  ali follow..  11  452IPEDARTLVAV------PCMLTSRDSVDEMM------------RNIEVHYLANPHGEI---------SLVSD--------WRDAPYEQSDEDLE---ILDYAKRELAALNLHRRRIYNSAEECWMG-------ERKRGKLHELNMLLRGDKDTTFLGGANIVPADVK--VMTLDADAVTKLVGKHPINRPKIDPVSGRVVEG----LLQPRVTPSLTTGKDASVFQRVFSINRGIDPYVFSEGTGLYDVDAFEAALKG-----RIEENSILSHD----------------LLEGSFARCAL-VTDVELVEDFPTRYEVGD----QLLPFIIDRARGVMVDNLRRSLAHFHTIWSEIRATNAQVALRIVFIADAACMM---DAIVRSLYRLLVSHKMLEWRTAASMQPVVAMLGLLFAALPGDNAFLIGIPFTLLWVLSPAVAWYVSQSAETEDRLFVSEHVSFELRKIARRYEAFVTPQENHLPPDNFQETVASRTSPTNIGVYLLSV----SARQFGWISFADTLERIENTIQTVEKMEKHRGHLYNWYHT-DTLQTLGPRYVSAVDSGNLAGHLIAVSSACRDWAEAPSAHLQGNLDGIGDVAGILRETLKALPDNRKTLRPLHRRLEERIIGFSNALASVKREHEFASIRVINLAVLARDIQKLATNVDHEVKAQLLVESCEAHISDSAIDLTNMEPLRQRLASLRDRSRNLAFSRKDRRLLSIGYRVESKELDEACYDLLASECRLT------SLFAIAKGD------LPTEHWYR-LGRQVVPIGAQGALVSWSGSMFEYLMP-PLVMQERQGGILNQTNNLIVKEQMN----------------HGRRLGTPWGISEAAFNARDH-NMNYQYTNFGV------------------PTLG-------------------------LKRGLGQNAVIAPYASILASQYDPDGAL................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 1408
30 -9.580[L] COG4581 Superfamily II RNA helicase  ali follow..  11  274............................................................................................................................................................ALDFPFELDFQKEAIYHLEMGDSVFVAAHTSAGKTVVAEYAIALAMTKAIYTSPIKALSNQKFRDFK-----HKFED----------VGILT----------GD--------VQVNPEGSCLLMTT-------EILRSMLYRGADLIRDVEFVEVH-----VNDLER----------------GVV-------EVIIMLPPHVTLILL--SATVPNTKEFASWVGRTKKKNIYV-ISTLKRPVP-----------LEHYLWVKQNMFKIVDQPVIAKDNKNSARGRGAARGRGVQTNMMRGRGSAKSVERRDANTWVHLIGHLHKQNLLPVIVFVFSKKRCEEYVDTLNNHQEKSEVHVVIEKAVARLKKEDRLLPQIGRMREMLSRGLAVHHGGL--------PIIKEIV----------------EILFQRGLVK-------VLFATET--------AMGVNPASVVFSGTGRNFRDLLPG-----EYTQCSGRAGR--RGLDVTGTVIILSRSELPDTASLR---------HMIMGPSSKLISQFRLTYNMILNLLRVETLRIEDM-IKRSFSENVNQTLVPQHEEKIKSFEEKLSALKKEMSDVDLKEIKSCLLSSESFKEYTKKMH............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 810
31 -9.550[I] KOG1406 Peroxisomal 3-ketoacyl-CoA-thiolase P-44/SCP2  ali follow..  14  13............................................................................RVFVVGVGMTKFVKPGAEPDLAEEAGKKALADAQIPYSAVDQACVGYVFG-------------------------DSTCGQRAIYHSLGMTGPIINVNNNCATGSTALFMARQLIQGGVAECVLALGFEKMSKLSAHPVAPQMFGYAGKEHMEKYGTKIEHFAKSDGAAAAILASEAFVQKYGLQSKAVILAQEMMTDLPSSIIKMVGFDMSKEAARKCYEKSGLTPNDIDVIELHDCFS-TNELLTYEALGTLVDRGDNTYGGKWVIN-GHPLGATGLAQCAELCWQLRGEAGKRQV------------------------------PGAKVALQHNLGIGGAVVVTLYKMGFPEAASSFRTHQIEAVPTSSAS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 428
32 -9.500[J] COG0525 Valyl-tRNA synthetase  ali follow..  13  22...........................................KHWEESGYFKPSEDTSKPSYSNVTGSLHMGHAFQQTLMDILIR-------FNRM--NTLWTGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDK---DWKAYSGGTISQQMRRLGNSIDWERERFTMDEGLSDAVKEVF-----VRLHEEGLIYRGKRLVNWDPKLHTAISDLEVENKESKGSLWHFRANGAKTADGKDYLVVATTRPETMLGDTAVAVHPEDERYQSLIGKTVVLPLANREIPIIADDYVDREFGTGVVKITPAH-------DFNDYE-----VGKRHQLPMVNVMTLNADIRAEAEIIGSDGKILESYTALIPTK-------------------------YQGMERFAARKQIVADFEELG----LLDEIKPHDLKVPYGDRGGVPIEPMLTDQWYVSVKPLAEVAVKAVEDGEIQFVPKQYENL-MRDIQDWCISRQLWWGHRIPAVARDEAEVRAKHNLPADLALKQD-VLDTWFSSGLWTFSTLG--WPKQTPDLKMFHST--DVLITGFDII-----WVARMIMFTMHFVKDENGKPQVPFK-TVYVTGLIRDEQGQKMSKSKGNVIDP---------LDMIDGIDLESLLEKRTGNM----------MQPQLAEKIAKATIKA---------PEGIAEHG-TDALRFTLTALATNGRDINWDMKRLEGYRNFCNKLWNASRFVLTNDKLDLSEGSVEYSVADRWIQSEFNRTVEAFRNALAQFRFDLCATALYEQFCDWYLELT-KPVLVNGSVAQKRGASQTLINV------------LEKLLRLTH--------------------PVMPFITEEIWHKVKAFAGVSGDTIMLQAFPQFEQSALDYQAEAEINWMKEVIVAV------RNIRAESNIPPSKGLDLLLRNLSEADQNALENNRTLIQA---MAKLDAIRVLEAGEDAPLSVAKLVNNAELLVPMAGFINKEAELARLNKEIEKYQGEIQRIENKLANEAFVAKAPPA.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 925
33 -9.270[C] COG1038 Pyruvate carboxylase  ali follow..  11  1...................................................................................................................................................................MVLLLYSAVQQNSVLACGETVLKISKILVANRSEIAI------VFRAANELGIKTVAIWAEEDKLSLHRFKADSYQVGRGPHLAKDMGPIESYLSIEEVIRVAKLSGADAIHPGYGLLSESPEFVEACNKAGITFIGPTPDTMR---------QLGNKVAARNLAISVD---PVVPATMAEEIGYLKASWGGGG-MRAI---KKEDLAREVTEAKREAKAAFGKDEVYLEKLV--------ERARHVESQILG--GNVVHLVVERAPAPY-----------------------LSEAQRQELAAYSLKIAAATNYIGAGT------------------------------------------------------VEYLMDADTGKFIEVNPRIQVEHTVTEVVIDIVKAQIHILEGAAI----TAESGVPKQEDIRLNGHALQCRITTE-------DPEHNFIPDYGRITAYRSASGFGI-----------RLDGGTSYTGAVITRYYDPLLVKVTAWAPEPDEAISRMDRALREFRIRGVATNLTFLEAIIGHDSFRNNTYTTRFIDSTPELFAQVKR-QDRATKLLTYLADVTVNGHPETKGRAKPADKAAKPIVPYIDAPTPDGTKQLLDKLGPKGFADWMRNEKRVLVTDTTMRDGHQS---LLATRVRTHDIARVASVYSKALPQLLSLEWGGATFDVSMRFLTEDPWERLSLIREGAPNRGANGVGYKNYPDNVVKYFVRQAARGGVDLFRV----DCLNWVENMRVSMDAIAEENKLCEATICYTGDLLNSARPKYDLKYYTNLLLKPAAAKVLFKALREATGLPIHFHTHDTSG--ISAATVLAAVDAGVDAVDAAMDAFSGNTSQP-CLGSIVEALSGSERDTGLDTEWIRRI...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 830
34 -9.130[Q] KOG1209 1-Acyl dihydroxyacetone phosphate reductase and related dehydrogenases  ali follow..  18  5...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DESPVVLITGSQGGIGHALAREFTEKG--RVVATSRS------RSTMTDLEQDS-RLFVKELDVQSDQNVSKVLSEVIDKFGKIDVLVNNAGVQCVGPLAETPISAMENTFNTNVFGNKDL-PHMVSKKKGKIVNVGSITVMAPGPWAGVYTATKAAIHALTDTLRLEGIDVINVVPG.............................................................. 203
35 -9.090[NU] COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1  ali follow..  14  591..................................................................................................VNNDLKANAKVAADAEKMVASLKQAFSRIVAE----------TKGAGTGLSSNSARLETGAVTYQAQFFGDLIAYHVDKVTGALTPFWNANFPAWEQRVITFANGTTLQDFTKKNLGETALASASAQ-----------NYLRGD--------RSQEGNVPGKRIRSGIMGDIVNSQ--------PLYVGAPNGRLYTTASFTGASAYAAFVAQQANRAPV------------------VYVGA---NDGMLHAFDANTG--KEIFAF----VPRAAEYTDQN--VDGELTAADIYDTKSGW--------RSVLVGTLGRGGKGLFALDVTDPSNIRL------------------LWDKTSAEIGGLGNTLSKPMIVQTSDGTWSVLLGNGPNSTADNAQ----LIVMNLLTGHATQVVVS-SNGLSGVLPWSSQSNGITDRVYAGLGTLWFTFSDNAWKVAPLFTAT---------------------------YQGKAQPISATPLGAITGRMWIFFGT------GRSSHDMDNKEVQSWYGLIDQGTTIPGRTGLSQV------------------QIVDEGVVNGYAVRTVSDPKNIGTDG--------------------YMDLISPKSGKQGERMIVSNMFRGAAL--------IGTTRIPDNSDICKLSGSGFVMAI................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 1135
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Lukasz Jaroszewski, Zhanwen Li, S. Sri Krishna, Constantina Bakolitsa, John Wooley, Ashley M. Deacon, Ian A. Wilson, Adam Godzik, Exploration of Uncharted Regions of the Protein Universe. Plos Biology. 2009 Sep. 7(9):e1000205