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Query: [V] COG3725 Membrane protein required for beta-lactamase induction, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTLGMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRNDSHARATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPVTLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHVLDWVPVRLAGVVYALIGHGEKALPAWFASLGDFRTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIALLTIYGALVLast
1 -102.000[V] COG3725 Membrane protein required for beta-lactamase induction  ali  100  1MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTLGMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRNDSHARATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPVTLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHVLDWVPVRLAGVVYALIGHGEKALPAWFASLGDFRTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIALLTIYGALV 284
2 -35.200[H] COG1270 Cobalamin biosynthesis protein CobD/CbiB  ali follow..  14  3IKLIVLSLALLLDRFIGDLPLLHPVVLLGKAISWGEKNFNDSSLTVGLVAACIFAGLVIRSILPHAGTAGAIAEVVIVAILLAQKSLADHVQAVAQALRDDGIEGGRKAVSMIVGRNPDRL--DEGGVSRAAIESLAENASDGIVAPAFWFLVGGLPGLFAYKFINTA---DSMIGHLNDRYRDFGRFAAKLDDVANYIPARLTGLLAALATAGRQALSIMCRDARLHRSPNAGWPEAAFAGALGLALAGPEARDIDAALVLFWSTMSLMTGLVIAASLVGLFV 326
3 -7.720[T] COG5040 14-3-3 family protein  ali follow..  9  38............................................................LSVEERNLLSVAYKNVI-------GARRASWRIVSSIEQKEESKEKSEHQVELICSYRSKIETELTKISDDILSVLLIPSATTGESKVFYYKMKG-----YHRYLAEFSSGDAREKATNASLEAYKTASEIATTELP--PTHPIRLGLAL-------FSVFYYEIQNSPDKACHLAKQAFDDAIAETLSEESYKDSTLIMQLLRDNLTLW.............. 233
4 -6.890[S] COG3898 Uncharacterized membrane-bound protein  ali follow..  10  2IRLLAFLIVVFALGLGFAWLADRPGDMVVTFNGYQYQV----SLMVAAVAIVAVVAAVMILWWLIRSLWNSPYTISRYFRVRRRDRGYQALSTGMIAAGAGDGALARKKTKEAAKLIRSDQEPLIHLLEAQASLL------------------EGDHEGARQKFESMLDDPEMRLYLEAERLGDRNAARHYAGRAAAVAPAESTLEELTARGDWDGALKLVDAQKSTRQIERDAVLLTAKAQSLADSDPNAARTAALEANKLQPDFAPAAVAAAAALFKQN... 277
5 -6.830[BD] KOG4563 Cell cycle-regulated histone H1-binding protein  ali follow..  9  479..................................................................................GSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQA--HLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQL--------GLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKI................. 653
6 -6.600[S] KOG2706 Predicted membrane protein  ali follow..  7  9..VICLLGCIGAGSYVKKIADEGQRKLVSTGLGVLVVVIVSGHSLHCFVSLALGTAAVLLVHPSKGHLVTFAVMFGYLVFFTNMIQMILTLKVSGIAFEKTAAWKRLQAHDEQKKNDQRDVHQESPIEITDYDVELQSLSAAEILHYSFNYVLTGP--YYRYRTYRDYFEMPFKTYAPTVEATLEKLKYAVFYCALYLATNYMWPLDYALSDEFFNDRSFVYRLLYVWPT----------------------------FFTFRARIYTGLTLSECVCTMAGF.. 273
7 -6.550[S] COG3014 Uncharacterized protein conserved in bacteria  ali follow..  13  4....................................................................FVLLMSVILGISLTGCIGYRMDLEHFNTLYYEESPKKAYEYSKQFTKKKKNA---------------------------LLWDLQNGLSALYARDYKTSLGVLDQAEQRFDKTQSAFTRGAGYVGATMEGVLINYYAIDYMLLNDSAKARVQFNR............................................................. 145
8 -6.440[S] COG4700 Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats  ali follow..  13  14...................................................................................................................................CIHAYRTGQERYWIFIIFCFPVIG---CVAYFVIVMLPETGADRHGHTLLMRNPERHLRKLTEELAIAET--LANELARLGRYHEAVPHYQQALSGIFAHEAAMMLSLAQAQFAIQEFAACQQTLEDVMRY...................... 150
9 -6.230[S] COG3523 Uncharacterized protein conserved in bacteria  ali follow..  12  14LAVVVLVLALLV--------------FVGPLVSFDTLRPLASVGSRVVTIALLLMLLVLWLVNWSMSIIGISV-LCLAIGFVTPL-LYGLYRLWRALRMDEQLLRRFLHPRGEEVPVAGEIKADLRTVNHIVTQAIRQLRQLRVLYELPWFMVVGSPGDGKTTALLNTGLQFPLAEQMEQTSRILTVPGGGTLHCDWWFTNE--AVLIDTAGRYARH-GEWQGFLHRPGAPLNGVILTLNVADLTAQSPAERLAACAALRARLAERFPVYLVVTKMDLLPGF.. 344
10 -6.140[O] KOG0841 Multifunctional chaperone (14-3-3 family)  ali follow..  9  36............................................................LSNEERNLLSVAYKNVV-------GARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKG-----YYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQ--PTHPIRLGLAL------NFSVFYYEILNSPEKACSLAKTAFDEAIAETLSEESYKDSTLIMQLLRDNLTLW.............. 228
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Liu T, Rojas A, Ye Y, Godzik A. Homology modeling provides insights into the binding mode of the PAAD/DAPIN/pyrin domain, a fourth member of the CARD/DD/DED domain family. Protein Sci. 2003 Sep;12(9):1872-81.