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Query: [G] COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPTLTFKLIFSYRIFIYLLVFVLFPILLFYNSSLLGVKSYNHEFLSKKSTDCIKGLSILVIILHHISLRMQPVGFMGIYTCLGHLAVSMFLFFSGYGLMVSKLKKKNYFKGFFSKRLSKVYLPFVIINAITIILTSLIFGTKFNLKDIIFYLSGLSLIDSTQWFVIAILVFYLCFYVCFKFLSTNLAQHILLFLTFVYFFAMIFMGFREWWYNTAFCFPLGVYAAINYDALTKFLEKHYVKTLIIALIAFTFFFFLAHMLPSAIMPLYQTIASIIFVYLVLLFLFKFRLSSKPLLFLGNIAYEIYLVHMKILVAFFSFIGARGSYIVYLYLILVIIVAFCFNKLFNLNKNKKVKLTLast
1 -107.000[G] COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation  ali  100  1MPTLTFKLIFSYRIFIYLLVFVLFPILLFYNSSLLGVKSYNHEFLSKKSTDCIKGLSILVIILHHISLRMQPVGFMGIYTCLGHLAVSMFLFFSGYGLMVSKLKKKNYFKGFFSKRLSKVYLPFVIINAITIILTSLIFGTKFNLKDIIFYLSGLSLIDSTQWFVIAILVFYLCFYVCFKFLSTNLAQHILLFLTFVYFFAMIFMGFREWWYNTAFCFPLGVYAAINYDALTKFLEKHYVKTLIIALIAFTFFFFLAHMLPSAIMPLYQTIASIIFVYLVLLFLFKFRLSSKPLLFLGNIAYEIYLVHMKILVAFFSFIGARGSYIVYLYLILVIIVAFCFNKLFNLNKNKKVKLT 356
2 -45.500[S] COG3274 Uncharacterized protein conserved in bacteria  ali follow..  13  4.............................................KIDWIDNLRAVACIMVVMIHSTTYYVTRGIANVLNSASRACVPLFFMISGYLFFGE--------KSAQKKHFMRIGLCLLFYSVIALIYISTLTPIDGW----SLRNILQKPVFYHLWFFYAIIVVYLVSPLIKVKPVSGRYLAILILLLAVVANPQTSKFS-GDTFYYLLYALLGRAMGMLETQGRMISWGAALLFVVSVICIAISTEKQTRINGSFADTFYMYCSPLVFIAAVSLWVWFKNCLIAWLSGLARHSLAIYGFHALIIHFIRTHHTAYPVLDILYVFALTLGLSTLLSMGLQRI........ 323
3 -38.100[G] COG3594 Fucose 4-O-acetylase and related acetyltransferases  ali follow..  16  26.................................................FDFAKGILITLVIIGHLLQYLIYQGTDAFWLSIYMFHMPLFMAISGYLSSGAILRKS--FTQGVGERAMQLLLPMLFWCTLIWTLKSAVIFPMKSLTDTLLDLS---EVIGTYWFIWAAFISFILIRVLTTFNRL--SIWIISASAIAVAFAPITLSITPLLKYTYPFYCLGFLFAQPIGWQNGVIWRYKWIFVVLLSIAAFICFLGWGKETYAYNSLAASAVAMQSMFQCWRLVYSTRVARFVAVQLGQSTLLLYLVQGAVFRLMDLIQLTTRITFATVLGVAIVVIAMAIRSIARN......... 348
4 -36.700[I] COG1835 Predicted acyltransferases  ali follow..  15  4..............................................RRDIDGLRAVAVLPVVLFHFGVS---------AIPGGFTGVDIFFVISGYLISDDLERGQFSIGRFYWRRARRILPALTFVILLASIASTFWSNIYFWKTTNYFSIDAELRPLLHTWSLSVEEQYYIFAPVLVYLIYRYASKRWLTILLPIAIGSFALTAGFYLLPTRIWELALGAMLMLRPPALASRPLTELIGLAGFGLIAFGFVTISESDPFPGYNALFPCIGTALLIYA---PVATQVLRLTPLVWIGLISYSLYLVHWPINSFVHYLSLKAGVPTILAMIVASVALATFSWKYVEQPFRQ..... 340
5 -36.200[S] COG4763 Predicted membrane protein  ali follow..  13  8.................................................INQIKGLCICLVVIYHSVITFYPHMWIYFNLYLAPFRMPVFFFISGYLIRRYIDSVP--WGNCLDKRIWNIFWVLALWGVVQWLALSALNQWLAPERDLSNALHGMITASTSLWYLYALIVYFVVCKIFSRL--ALPLFALFVLLSVAVNFVPTPWWGMNSVIRNLPYYSLGAWFGATIMTCVKEVPLR----RHLLMASLLAALAVGAWLFTISLLLSLVSIVVIMKLFYQYEQRFGMRSTSLLNVIGSNTIAIYTTHRILVEIFSLTLLA-LLVYPFVSLFICTVAGLLVRKLSQRA........ 338
6 -26.600[S] COG4645 Uncharacterized protein conserved in bacteria  ali follow..  11  26................................................RLDVFRALCLLTIFVNHVPGQYLEYLTHKNFGFSD--SAEAFVLISGLSVGAAYSGK-LALTLKIWRRALALYVAHIMTSVVTLAIFAGGALYF-QTEQGIVAMVLLGHQLGYNNILSMYAVLFLLLPGFLWLNAVRPRLLFAFSATLWLAAGCFKMVPYNF-WSWQFLFVIGILCMSHVRRGGSLPRSPWLLGISVAYLAISAFWVFDKTFLSLTRLLHVLALAYILATVPVFSRLTRVGSNHPLVMIGRHSLAVFIFGTILAMAGQVLLLVTDRDRIIGTIFVIGGIGLHF............... 364
7 -26.200[R] KOG3700 Predicted acyltransferase  ali follow..  15  244.....................GVEDFHGILALSKCQGDIQNEAEGQVTSLNCIRTISTVWVILGHCAAMLILKTYMGALLVNAYFAVDTFFFISAFLLSFLWFKQ-GGWMMFYVHRIARLSPAYYIAILFVTFVYIRMLRDMPLNLLYIENIVDTKNIYVISWYLATDLQLYLMSPILLLSFAIGGAVFGLFASVVALVASTAFNAYQIFFLIRCQIYIMGLVLGYFMRKVPKININPWVDRIMWVLSLGSMVFVVLIYNCFSRVLWGFAMSWIVISTYYRKGLIRDFMSLSFWTPLARLSFCAYLVHWMVLGYFFGRNHSELYFSVIPVTALSFVIAIFWSSMFEIPFAKIEGL. 731
8 -22.900[S] COG3503 Predicted membrane protein  ali follow..  14  10.............................................RLHSIDALRGLVMLFMLLDHVRETFFLHRQVGLSRTLAHLCAPVFVFLTGLSAFLYGEKGRRAVSAFLFKRGLFLVALELTLVNFAWTFQLPPTVIYLQV-------------------IWAIGLSMLALAALLWLPRPLLAALGVLLVAGHNLLDPLHFAPGSALLPWIGVIALGYAAGNWFSGATPATTRRRYLLAGGGGLLLGFILFFNVTKYPPSLLFLALTLGIGLLLLAWFERLDWSGRGKALVAFGGAPMFFYLLHLYLLKLLYLLALFSSVPALWLCSILLAVALYPAVHWFAGFKAR..... 374
9 -15.500[R] KOG1699 O-acetyltransferase  ali follow..  11  125...LLGDSTKNYNRDLFLFLYVLLIIVSAMTSLRKHNDKSPISYLNRHQTEEWKGWMQVLFLMYHYFAAAEIYNAIRIF-------IAAYVWMTGFGNFSYYYVRK----DFSVARFAQMMWRLFFVAFCCIVLNNDYMLYYICPMHTL-------------FTLMV----YGALGIFSKYNEIGSVMALKIFSCFLVVFLLWEIPGAFEIFWGPLTFLIGMIYAYYHPTVERWLSIKAAIVTITVLVGYVWYECIYKLDRTSYNMYHPYTSWIPITSVHKT-------FLLVFIFVSYVT....................................................... 435
10 -15.400[S] COG2311 Predicted membrane protein  ali follow..  15  3.............................................RNVTLDFVRGVAILGILLLNISAFGLPKAAYLNPAWYGAITLTLFALLFGAGLQMLLPRG----RRWIQSRLTLLVLLGFIHGLLF-------------------------------WD---ILLAYGLVGLICWRLVRDAPSVKSLFNTGVMLYLVGLGVLLLLGWQLAGMMLIGAALMRSGWLKGQFSLRHYRRTGFVLVAIGVTINLPAIALQWQLDW-PFQAIGYASLFYGFWPQLSRFKLVLAIACVGRMALTNYLLQTLICTTLFYHLGLFMHFDRLELLAFVIPV-WLANILFSVIWLRYFRQG 362
11 -12.700[S] KOG4683 Uncharacterized conserved protein  ali follow..  12  36.............................................RLASLDIFRGLTVALMIIAHAP---------------GCNLADFFLFIVGVSIALSLKRKFEACKKVGFRTCKLLFWGLLLQGGFSHAPDELTYGVDVTMMRFC--------------ILQRIALSYLVVALVEIFTKDSHEENLSTGRIVAASVLVIYLATLYGSISAILSTIIGVHFGHIILHLKGHSARLKHWISTGLVLLALGLLNKQLYSFSYICVTSGAAALVFSSLYSLVDILEWKHMFLPLKWIGMNAMLVYVMGAEGILAAFFN--GVLMYVIFAEILFWGLVTGVFHR-----FKIYWKL. 455
12 -11.600[S] COG4299 Uncharacterized conserved protein  ali follow..  12  7.............................................RFLSLDVFRGLTVFLMILVHAP---------------GFTAADAFLFAVGCSMAFAFSKLNDFTVKVLRRAALIFLLGFLMYWFPFVRKVDGDWALIPFSDTRVMGV------------LQRIALCYLLAAFAVRWLSPRLIVALCAVLLLGYWAILMAFGDPA-TLPSTVNVLAGYLAARFLKENPGSSQAMGRMAIAGLVLILAGLVWSPLFTSSFVLLTVGIDLILLAGLAKLLEGKASNPGTYFFQVFGLNPLVLYLFSELFVVVLGMIEVAPSLLCALAYTLVCWLLGYVMAR............. 365
13 -9.320[O] KOG2292 Oligosaccharyltransferase, STT3 subunit  ali follow..  10  1MNRTPKMLNSKVAGYSSLITFAILLIAWLAGFSSRLFAVIRDPWFNYRATAYM-GLMITSGGIHWLLHVLNIPVHIRDICVFGLTSISTYLLFAASFIAIVPGYISRSVAGSYDNEGIAIF--ALQFTYFLWVRSVKTGSVFWSAAAALSYFYMVS-----AWFIINLIPLHVFVLLIMGRYSPRLLTSYSTFYILGLLFSMQIAALGVFVLLMAVATLRHLQSVLSRNEFRKLFIVGGLLVGVGVFVAVVVLTMLGVVAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTTWFSFFFDLHILVCAFPVGVWYCIKQI--NDERVFVVLYAISAVYFAGVMVRLMLTLTPVVCMLA 419
14 -9.140[P] KOG4505 Na+/H+ antiporter  ali follow..  9  56AKLFVPTSWGNTDYITEELARVLLVVEVFAAGAELPRAYM------LRHWRSMFVMLLPVMIFGWLVSTGFMYALIPRLSFLESLAIAACITATDPVLASSIVGKGKFARR-VPGHLRNMLMAIPFLYLAIYLIIEKPARHAGRDWVCIIILYECTFGCVLGAIIGVIARKMIKFSERRGLMDRESFLVFYFVLALFCGGIGTIIGVDDL----LVSFCAGAAFSWDSWFSKKTEESHVSNVIDLLLNLSFFVYVGAIMPWPQFHMPHMDLSVWRLVVLAICILIARRIEALFAGHFGALYTCLVARAELDAIENPEIPNWYCIQVMWPVVCFLVLSSIIVHGSSIAFFMLGKRIN 441
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. Discovering new genes with advanced homology detection. Trends Biotechnol. 2002 Aug;20(8):315-6.