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Query: [R] COG3943 Virulence protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSIILYTANDGTAQFALQEFGGQLWLTQADMAELYQTTKQNISKHIKTILAEQELEEKATVNFQLTVQNENGRKVNRKIAHYSLPMIIAVGYRVRSARGIQFRQWATERLDEYLTKGFAIDDERLKGTGGGDYWKELLNRIRDIRSSEKALYRQVLDLYATSQDYNPKSSESQTFFAAVQNKLHYAASRQTAAELIYSRADSSKDFMGLTTFQGAIPTLNEAKIAKNYLTEDELFRLNRLVSAFFDLAEIKAQEQSPMYMRDWIAELDKFSGLYGQGTLQGAGSISRKQAEQKAEREYRAYEARILSPVEQAYLESVKALEKTAVQQIKQKKDRTKLast
1 -115.000[R] COG3943 Virulence protein  ali  100  1MSIILYTANDGTAQFALQEFGGQLWLTQADMAELYQTTKQNISKHIKTILAEQELEEKATVNFQLTVQNENGRKVNRKIAHYSLPMIIAVGYRVRSARGIQFRQWATERLDEYLTKGFAIDDERLKGTGGGDYWKELLNRIRDIRSSEKALYRQVLDLYATSQDYNPKSSESQTFFAAVQNKLHYAASRQTAAELIYSRADSSKDFMGLTTFQGAIPTLNEAKIAKNYLTEDELFRLNRLVSAFFDLAEIKAQEQSPMYMRDWIAELDKFSGLYGQGTLQGAGSISRKQAEQKAEREYRAYEARILSPVEQAYLESVKALEKTAVQQIKQKKDRTK 336
2 -8.100[S] COG3646 Uncharacterized phage-encoded protein  ali follow..  17  1MELVYMD------------GKKEPYTTSEIIAECAEVQHHTITRLIRENKADFE-ELGILGFKIHKLDTRG-----QPKKSYILNTFLITYLK-NTETVRQFKL--------NLVKAFFEMREELSE................................................................................................................................................................................................................. 104
3 -7.010[S] COG4353 Uncharacterized conserved protein  ali follow..  15  22..........EEYNVELFLEGERLWA------EVFNINPVFIGTEWEKIYC---LHRLMSPGDILYVEYVDDRETFIALQKGEAPEATRLGALLRKCGFKIVKNW-------YHPEGGLEGGMKLQAVK............................................................................................................................................................................................................... 141
4 -6.270[V] COG3023 Negative regulator of beta-lactamase expression  ali follow..  12  33.....FGPRRDGKQPVFLILHYTGLATAKEAMDVLKSPEMEVSAHY--VHEDGRVVQMVSEKARAWHAGKSFWKGETDINSASIGIIVNPGVLENYPPFHDAQIEAVIRLCQDICKRHEIRPENV................................................................................................................................................................................................................... 152
5 -6.230[K] COG1497 Predicted transcriptional regulator  ali follow..  18  1MKALRKKGELTRFQILSEIAMRQPYVRQKDIADKLGVTVQAVSENIKSLIAEGLVESGSGRSHYK-ITRRGAEKIKEAAMDLR............................................................................................................................................................................................................................................................. 82
6 -5.950[S] COG5451 Predicted secreted protein  ali follow..  16  95.............................RLSEILGA------QYLRTL-SGPEDWRKSMSALLAADTASEPERRQRMTAAFN-------GYRSFAAIHTSCTRAAIMAEENYRNEGATLAQE..................................................................................................................................................................................................................... 179
7 -5.950[G] COG3469 Chitinase  ali follow..  10  45.VLVGYWHSWKSSGKDGYQQGTSADIALKDTPKAYN--------VVDVSFMKGDGVNRIPTFKPVGINDSDFRAQVGALNKEGRAVLLALGVELKAGDEQAFANEIIRQVETYGFDGLDIDLEQITAGDNKTVIPAALKIVKDHYKAQGKNF........................................................................................................................................................................................ 194
8 -5.790[S] COG3398 Uncharacterized protein conserved in archaea  ali follow..  11  178.KVVSALQNATNQRIISEIQNGK--NTNLALAREIGVSRATISWYVKNLKETGLIDET----------RSGRSII----------------YSINPSYEPLIEKYG...................................................................................................................................................................................................................................... 255
9 -5.740[K] COG1654 Biotin operon repressor  ali follow..  15  11................ISLLADGEFHSGEQLGERLGMSRAAINKHIQTLRDWG----------------------------VDVFTVPGKGYSLPE................................................................................................................................................................................................................................................ 62
10 -5.710[K] COG3561 Phage anti-repressor protein  ali follow..  14  15...................NETTLLVNARDLHTFLGVGKR-FASWITERIEEYGFVENQDYIAISQKREIGYGRGKKDY-HLTLDTAKETAMVERNEKGRQIRRYFIECEKKL............................................................................................................................................................................................................................... 106

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Robinson-Rechavi M, Godzik A. Structural Genomics of Thermotoga maritima Proteins Shows that Contact Order Is a Major Determinant of Protein Thermostability. Structure (Camb). 2005 Jun;13(6):857-60.