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Query: [P] COG4150 ABC-type sulfate transport system, periplasmic component, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKQNSVKKNARNGLTHIALFSALILSGVTASATELLNSSYDVSRELFTALNPGFQAQWEQQNPGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQITDVQILHDRGNLIPADWQARLPNNSSPFYSTMAFLVRKGNPKNIRNWDDLVREDVKLVFPNPKTSGNGRYTYLAAWGATQLADGGDEAKTRDWMKRFLKNVEVFDTGGRGATTTFVERGLGDVLISFESEVNNIRKEYGSDQYEVIVPPVDILAEFPVAWVDKNVEKNGTEKAAKAYLNYLYSPPAQQVITRFNYRVYDKAAMEAAKSQFPDTKLFRVEDQFGSWPQVMSTHFTTGGVLDKLLAEGHQLast
1 -123.000[P] COG4150 ABC-type sulfate transport system, periplasmic component  ali  100  1MKQNSVKKNARNGLTHIALFSALILSGVTASATELLNSSYDVSRELFTALNPGFQAQWEQQNPGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQITDVQILHDRGNLIPADWQARLPNNSSPFYSTMAFLVRKGNPKNIRNWDDLVREDVKLVFPNPKTSGNGRYTYLAAWGATQLADGGDEAKTRDWMKRFLKNVEVFDTGGRGATTTFVERGLGDVLISFESEVNNIRKEYGSDQYEVIVPPVDILAEFPVAWVDKNVEKNGTEKAAKAYLNYLYSPPAQQVITRFNYRVYDKAAMEAAKSQFPDTKLFRVEDQFGSWPQVMSTHFTTGGVLDKLLAEGHQ 345
2 -99.000[P] COG1613 ABC-type sulfate transport system, periplasmic component  ali follow..  42  1MSSNSL--AGIVKLALVVGSLQLGSIGLALADTTILNVSYDPTRELYKEFNAAFAEKWQADT-GETVTIQTSHGGSGKQARSVIDGLEADVVTLALEADIDAIAKESGKIPADWKSRFENNSAPYTSTIVFLVRKGNPKAIKDWGDLVREDVQVITPNPKTSGGARWNFLAAWAWARAANNGDDAKAQEYVAQLFKHVPVLDTGARGATTTFVQRGLGDVLLAWENEAYLSLEELGPDNFDIVTPSISIKAEPPVALVDGNVDSKGTRKVAEAYLDYLYSDVGQKIAAKHYYRPFKPELADPKDTARFTELKLVTIDDFGGWKEAQPKFFGDGGVFDQIYRPGQ. 341
3 -56.500[R] COG4588 Accessory colonization factor AcfC, contains ABC-type periplasmic domain  ali follow..  13  1.............MKKIITLFGACALAFSMANADVNLYGPGGPHTALKDIANKYSEK-------TGVKVNVNFGPQATWFEKAKKDAD-ILFGASDQSALAIASDFGKDFNVS------KIKPLYFREAIILTQKGNPLKIKGLKDLANKKVRIVAGKSNTSGTGVWEDMIGRTQDI-----------KTIQNFRNNI-VAFVPNSGSARKLFAQDQADAWITWIDWSKSNPDI-----GTAVAIEKDLVVYRTFNV----IAKEGASKETQDFIAYLSSKEAKEIFKKYGWR.................................................... 249
4 -53.800[P] COG0725 ABC-type molybdate transport system, periplasmic component  ali follow..  14  2.......AHSWLRLVAGATLSFVIAGHALADEGKITVFAAASLTNAMQDIAAEYKKE-------KNVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAADKKAVDTTTRET-------LLGNSLVVVAPKASEQKPFTIDNKTD---RLAVGDPQHVPAGIYAKEALQKLGAWQTLEPK---------------LAPGEDVRGALALVERNEAPLGIVYGSDAVASKGV---NVVATFPEDSHKKVEYPIAIV-----EGHKNATVSAFYDYLKGPQASAIFKRYGFTT................................................... 256
5 -49.600[H] COG2998 ABC-type tungstate transport system, permease component  ali follow..  12  1MEFTMKK---TTFTLAAASLILVSYSASSADDARIRLATTTSTYDSLDYLLPKFEQD-------TGYKVDVIATGTGKALKMGENGDVDLVMTHAPKAEASFVEAGFGV----------LPRKLMYNDFVVVGPESDPAKIADEKNIAKVFENIAKSGAVFISRGDDSGTHKKELGIWAQNKIEPNFGGYRS---------IGQGMGPTLNMASEMQAYTLTDRGTWLAYNNKL---ALKILFEGDEQLFNPYQVIIVNPERYPTTQYHAAKVFSDWLVNPKGQQLINEFKFVANADK............................................... 274
6 -38.100[H] COG4143 ABC-type thiamine transport system, periplasmic component  ali follow..  15  1.............MLKKYLPLLLLCAAPAFAKPVLTVYTYDSFWGPGPAVKKAFEAD-----CNCELKL-VALEDGVSLLNRLRKNSKADVVLGLDNNLLEAATQTKLFAKSGVANE-DTFVPFDYGYFAFVYDKS-KNPPKSLKELVESDQKVIYQDPRTSTPGLGLLLWMRKV---------DNAPQAWQKLAAKTVTVTKGW-SEAYGLFLKGESDLVLSYTTSPAYHIIEEKKDNYAAANFSEGHYLQVEVA---ARTVASKQPELAEKFLKFMVSPAFQNAIPTGNWMPVADVALPAKPATTLEFTPQQVAAQRQAWISEWQRAVSR............. 327
7 -36.500[P] COG1840 ABC-type Fe3+ transport system, periplasmic component  ali follow..  13  11IQTQTMEEIMRLTIISSLLLAGTTLLGVPAHAAGDLNLICAADVVICEQMKGDFEKT-------HDIKVNMVRMSSGEAYAKIRRNPKTDLWWAGTGDPHLQAASENLTLEYKTVGVYAGALGWGYNT---IFKKKGYKEPKCWADLLAPELKIQIANPNSSGTAYTALASLVQI-------GEDQAFDYLKKLNGNISQYTKSG-SAPVKAAARGETAVGIVFMHDAVAQTAE--GFPVKSVAPCEGTGYEIGSMSI---VKGARNLENAKTWYDWALQPDVQSRMKDAKSFQLPSNKTAEIPKEAPRFEDIKLINYDFKTYGDPEKRKALLERWDKDVGAAAN 360
8 -24.100[R] COG4134 ABC-type uncharacterized transport system, periplasmic component  ali follow..  10  1.....MMRHCGWLLGLLSLFSLATHASNEAKGQTVWFNAWGGINRYLDWVSGEMKTHY-------AINLKIVRLADAEAAAGRKTGGSVDLLWVNG-ENFRTLKEANLLQTDWAETLPNWRYVWGGAQLTFIARRDVPQPPQTPQALLE---TVTYPRPPDFTGTAFLEQLLIMLT--TFARVTAPLWQYLDALHPYLWREGKPSPARMDALLKAGTFRLSLTFNPAHAQQKIASGDASSYSFGFREGMIGNVHFVTI---PANANASAAXKVVANFLLSPDAQLRKADPAVQKLPDGQRETLQSRMPQDLPPVLAEPHAGWVNALEQEWLH............. 384
9 -20.800[E] COG0687 Spermidine/putrescine-binding periplasmic protein  ali follow..  11  1.....MMKRFGKTLLALTLAGSVAGMAQAADNKVLHVYNWSDYIA--PDTLEKFTKET-------GIKVVYDYDSNEVLEAKLLAGKSGDVVVPSN-SFLAKQIKAGVYQKLDKSKLPNWKNLIGYNPDKVKAAFGDNAPVDSWDLVFKPENIVSFLDSPTEILP----AALHYLGYKPDTDNPKELKAAEELFLKIRPYVTYFHSSKYISDLANGNICVAIGYSGDIYQAKSRANKVTVKYNIPKEGAGSFFDMVAI---PKDAENTEGALAFVNFLMKPEMAEITDVVQFPNGNAAATPLVSEAIRNDPGIYPSEEV--WTKIKS.................. 365
10 -15.200[P] COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component  ali follow..  10  1MISRRSALVIAAGLSALALASCSGKSDAPAANNEVTFSILSTEST--QNMESYWTPILKDMEKQTGLKVKPFFSSNYSSLIVAMGAKQTDLGWFSNQSGLEAVRRSNGEVFARTFDPSGTDGYKS----VIIVPADSK--IQSVQDLLKKSLDFGIGDKKSTSGTLAPMTYVFIPANKKPET---------------FKTVISANHQANLFAVANGKLDASTNNSTAIGLSKARGEGVTDKIRVIWESPTLPEDPLVWRKDIDPVVKEKLRQFFLTYPEAEQQRGYLKRLGFKPADDT............................................... 286
11 -15.000[G] COG1653 ABC-type sugar transport system, periplasmic component  ali follow..  13  1MFNNSI------HKVSICIALTLTFSANAMAVTEIPFWHSGELGKEVDSIADRFNQS------QPDYKIVPVYKGNAAGIAAFRSGKAPAILQVYEV-GTATMMASKAIKPVY--PFNSSTPVLYYNKEAFKKAGLDPEQPKTWQELAADTAKLRAAGSSCGYASGWNGFDGTDAVLEFNKPLQVKHIQLLSDMNKKGDFTYFGRKDESTSKFYNGDCAITTASSGSLASIRHYAKFNFGVGMMPYDADAKNAPQNAIIGGASDKETYKGVAEFLQYLVKPEIAAEWHQTGYLPITTAAYE............................................ 357
12 -14.700[G] COG2182 Maltose-binding periplasmic proteins/domains  ali follow..  12  1MK----IKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKF--EKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAH-DRFGGYAQSGLLAEITPDKAFQDKLYIAVEALSLIYNKD-PNPPKTWEEIPALDKELKAKGPLIAADGGYAFKYENGKYDIKDVGGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINWAWSNIDTSKVNYG-VTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKD--PRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQT 392
13 -14.300[P] COG0226 ABC-type phosphate transport system, periplasmic component  ali follow..  11  5IKRIKNNRIPVSITVLTLAMSLAACGGQQGSDNSLTGAGASFPAPLYASWFTDLNKK------YPNLQINYQSVGSGAGVEQFIQG-TVDFGASDVAMKDEEIQKVQ-------------LLPVTAGGIVLAYNLPGVTKIKTWDAVNLPSQPITV---RSDGSGTTGVFT----KHLAAVSPEWKSKVGEGKSVSWPVGVGGKGNEGVTAQIKQTQGAIGYIYAKQNNISYATLENKAGKFVKYNDESASQYPIVMAYKNYPDPVKAKAMEAAIEYALT-EGQKISGELGYIPLPQAVVQKTATVADQIS.................................. 376
14 -12.700[R] COG2358 TRAP-type uncharacterized transport system, periplasmic component  ali follow..  9  1MSLSRR-------FGLFTLAATVTFSTSVFAAPTFINILTGGTSGVYYPIGVGLSQIYGHDIQGAKTSVQAT-KASVENLNLLQAG-RGELALALGDSVADAWNGVADAGFKAPLKKLRAIGNTYPNYIQVVASQAS--GIKTLADL--KGKRISVGAPKS-GTELNARAIFKAAGL-----------------YEDMGKVEYLPYAESVELIKNRQLDATLQSSRDLASTMPITFVAIPADVVAKIDSPAYHAASIPAGTYDGQEQDVPTVAIDNILVSHSGVSDELAYQMTKLMFDNLPRLVTAHAAAKDIALDKAAKN-HPGAERFYKEKGVLPE....... 319
15 -12.200[P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen  ali follow..  13  1MNKEIMKFSLKSLLTIAAAASTLILAGCGEKAVDNNKVKIGVMAGAEAQVAEVAAKVAKEKY---NLDVELVTFTDYVTPNAALDDGSIDANAFQHKPYLDKQIAD-------------RGYKLAIVGNTFVYPIA-SKQIKSVDEL-QDGARIAVPNDPTNLG---SLLLLQQQGLLK-LREDVGLLATVRDIVENPKKLEILELDAAQLPRSLDDVALSIINTTYASSINLTPEKDGIFVENKES------PYVNILVAREANVNAENVQNFKKAYQTDEVAKAASE........................................................ 265
16 -10.900[E] COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components  ali follow..  7  1.....MLKQITAMTAGLLMTIGVAAAAEPESCKTVRFSDVGTDITSTTAVASTILEAL-------GYAPQSKLLSIPVTYASMKNK-DIDVYLPSMEADRKPFLEDKSIEVIGPNLTGAKYTFAVPK-----VADAGVKDISDLQKFPDKFGRKIYGIEPGNNGNRMILDMINKGDFGLTGWELVESSE-------------QGMLAEVERATKDDQWIVFLGWAPHPMNTR-----QIDYLSGADAYFGPNYGGADIYTNIRAGQECPNVARFVT-FTLEMENEIMNGILNDGNDPKDAAAD------------PEAVAPWLEGVTTFDGAPAK-EAVESALKS 312
17 -10.700[M] COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)  ali follow..  11  1MTI--------SKLWVSSLALLATVSLPLQAASPVTVGSKIDTEGAL--LGNMILQVLESH--GVKTVNKIQLGTTPVVRGAITAG-ELDIYPEYTGNGAFFFKDENDPAWKNAKQGFEKTPAPANNTWTIAIRQDEKNKLSSLADLSRGTFKLAASAEIERADALPAFEKAYDFTLNQNQLLSLAGGDTAVTIKAAA--------------QQTSGVNAAMAYGTDGPVAALG-----LQTLSDPKGVQPIYAPAPVVRESVLQAYPQIADW-LQPVFASLDEKTLQQLNARIAVEGLDA---------------------KKVAADYLRQKGWVK........ 305
18 -9.520[P] COG1910 Periplasmic molybdate-binding protein/domain  ali follow..  15  101................................................................IQETPLRKYKGSLNSLIDMYQGK-VSLHLYDAETGQYNAPYVKRILTGEPFCLIN----VVLRKAGLYVQKGNPKNIQGWKDLKRADIRIINREKGS------GARVLLDEQLGLLGVNPADVVGYGDIVTDHY---------AAASQVSSGQADAGIGAQHAAHMGS--LIDEQYDIVVLKKN---EQLLKAVKEILNSEDYKANLSHLNGYETKLTGKVILET........................................................ 308
19 -9.270[P] COG4521 ABC-type taurine transport system, periplasmic component  ali follow..  11  1..........MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAK-----AQADNTFAKESGATVDWR-KFDSGASIVRALASG-DVQIGNLGSSPLAVAASQQVPIEVFLLASKLGNSE-------ALVVKKT----ISKPEDLIGKRIAV----PFISTTHYSLLAALKHWG-----------------IKPGQVEIVNLQPPAIIAAWQRGDIDGAYVW--APAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHPEVVKAFSKWLKQPENISKLARLSGVPEGPGLVKGNTYLTPQQQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQ 312
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Erlandsen H, Godzik A. HEPN: a common domain in bacterial drug resistance and human neurodegenerative proteins. Trends Biochem Sci. 2003 May;28(5):224-6. Review.