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Query: [S] COG4645 Uncharacterized protein conserved in bacteria, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLQKTFEGGNDQRGVAHPVPTGRDTRLDVFRALCLLTIFVNHVPGQYLEYLTHKNFGFSDSAEAFVLISGLSVGAAYSGKFLAGGRLALTLKIWRRALALYVAHIMTSVVTLAIFAGGALYFGRQELIGEINIRPIVEQTEQGIVAMVLLGHQLGYNNILSMYAVLFLLLPGFLWLNAVRPRLLFAFSATLWLAAGCFKMVPYNFLDDGYWFLNPWSWQFLFVIGILCMSHVRRGGSLPRSPWLLGISVAYLAISAFWVLFSWWNIDLSFGLPAVLTGFDKTFLSLTRLLHVLALAYILATVPVFSRLTRVGSNHPLVMIGRHSLAVFIFGTILAMAGQVLLLVTDRDRIIGTIFVIGGIGLHFAYAYYLEWLKEVSVAPPLKAALast
1 -114.000[S] COG4645 Uncharacterized protein conserved in bacteria  ali  100  1MLQKTFEGGNDQRGVAHPVPTGRDTRLDVFRALCLLTIFVNHVPGQYLEYLTHKNFGFSDSAEAFVLISGLSVGAAYSGKFLAGGRLALTLKIWRRALALYVAHIMTSVVTLAIFAGGALYFGRQELIGEINIRPIVEQTEQGIVAMVLLGHQLGYNNILSMYAVLFLLLPGFLWLNAVRPRLLFAFSATLWLAAGCFKMVPYNFLDDGYWFLNPWSWQFLFVIGILCMSHVRRGGSLPRSPWLLGISVAYLAISAFWVLFSWWNIDLSFGLPAVLTGFDKTFLSLTRLLHVLALAYILATVPVFSRLTRVGSNHPLVMIGRHSLAVFIFGTILAMAGQVLLLVTDRDRIIGTIFVIGGIGLHFAYAYYLEWLKEVSVAPPLKAA 385
2 -34.600[S] COG3503 Predicted membrane protein  ali follow..  12  2..............PNSISNSSRLHSIDALRGLVMLFMLLDHVRETFFLHRQVGD-----CAPVFVFLTGLSAFLYGEKHQGRR---AVSAFLFKRGLFLVALELTLVNFAWTFQLPPTVI----------------------------------YLQVIWAIGLSMLALAALLWLPRPLLAALGVLLVAGWAVLHDRGWIEAGDALRLRTSYPLLPWIGVIALGYAAGNWFSGATPATTRRRYLLAGGGGLLLGFILLRLLNGYAFGETPAITLMGFFNVTKYPPSLLFLALTLGIGLLLLAWFERLDWSGRGKALVAFGGAPMFFYLLHLYLLKLLYLLALAIWSSVPALWLCSILLAVALYPAVHWFAGFKARRRD...... 377
3 -28.400[G] COG3594 Fucose 4-O-acetylase and related acetyltransferases  ali follow..  8  1MLDNIRAGAKGRGSCP-AGTNNRDLSFDFAKGILITLVIIGHLLQYLIYQ-PYFKSIYMFHMPLFMAISGYLSSGAILRK-------SFTQGVGERAMQL----LLPMLFWCTLIWTLKSAVIFPMKSLTDTLLDLSTEVIGTY------------------FIWAAFISFILIRVLTTFNRLSIWIISASAIAVAFAPITLSITP-------LLKYTYPFYCLGFLFAQPIGWQNGVIWRYKWIFVVLLSIAAFICFLGWGKETYAYNNLVLIHDEQSAKQVFLMFSGSLAASAVAMQSMFQCWRLVYSTRARFVAVQLGQSTLLLYLVQGAVFRLMDLIQFGEVWNLTTRITFATVLGVAIVVIA.................. 339
4 -26.600[G] COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation  ali follow..  11  49.........................STDCIKGLSILVIILHHISLRMQPVGFMGIYTCLGAVSMFLFFSGYGLMVSKLKK------NYFKGFFSKRLSKVYLPFVIINAITIILTSLIFGTK----------------NLKDIIFYLSGLSLIDSTQWFVIAILVFYLCFYVCFKFLSTNLAQHILLFLTFVYFFAMIFMGFREW----------YNTAFCFPLGVYAAINYDALTKFLEKHYVKTLIIALIAFTFFFF-------------------LAHMLPSAIMPLYQTIASIIFVYLVLLFLFKFRLSSKPLLFLGNIAYEIYLVHMKILVAFFSFIGARGSYIVYLYLILVIIVAFCF..................... 341
5 -26.300[S] COG4763 Predicted membrane protein  ali follow..  11  2....................KQKELWINQIKGLCICLVVIYHSVITFYPHMTTFQHPLSEVLSVFFFISGYLIRRYIDSVPWGN--------LDKRIWNIFWVLALWGVVQWLALSALNQWLAPERDLSNASNAAYADSTGEFLHGMIT-------------YLYALIVYFVVCKIFSRLALPLFALFVLLSVAVNFVPTPWWG---------SVIRNLPYYSLGAWFGATIMTCVKEVPLRRHLLMASLLAALAVGAWLFTISL-----------------------LLSLVSIVVIMKLFYQYEQRFGMRSTSLLNVIGSNTIAIYTTHRILVEIFSLTLLAQMNAARWSPQVELTLLLVYPFVS.................. 320
6 -25.200[S] COG3274 Uncharacterized protein conserved in bacteria  ali follow..  10  2....................TNKIDWIDNLRAVACIMVVMIHSTTYYVTRGAQVG-----CVPLFFMISGYLF-------------FGEKSAQKKHFMRIGLCLLFYSVIALIYISTLT------------------PIDGWASLRNILQKPVFYHLWFFYAIIVVYLVSPLIKVKPVSGRYLAILILLLAVVANPQTSKFSLDDFRLLPANLYIYGDTFYYLLYALLGRAMGMLETQGRMISWGAALLFVVSVICIAISTEKQTRINGSFADTFY-----MYCSPLVFIAAVSLWVWFKNC-------LNQHIAWLSGLARHSLAIYGFHALIIHFIRTHHYDFTAYPVLDILYVFALTLGLSTLL.................. 316
7 -22.600[S] KOG4683 Uncharacterized conserved protein  ali follow..  11  14LLEPKEDTSSSYTRRSLAGNRPRLASLDIFRGLTVALMILVDDAGGDWPMIAHAPWNGCNLADFFLFIVGVSIALSLKRISNKFACKKVGFRTCKLLFWGLLLQGGFIALSYLVVALVEIFTKDSHEENLSTGRIVAASVLVIYLATLYGTYVPDWENAVGYVDRQVLGINHMYHHPAWRRSKACTDDSPYEGAIRQDAPSWCRAPFEPEGILSSISAILSTIIGVHFGHIILHLKGHSARLKHWISTGLVLLALGLTLHFTHL--------------LNKQSFSYICVTSGAAALVFSSLYSLVDILEWKHMFLPLKWIGMNAMLVYVMGAEGILAAFFFIRVWHSRRVGVLMYVIFAEILFWGLVTGVFHRFKI......... 451
8 -20.100[S] COG4299 Uncharacterized conserved protein  ali follow..  12  2.................SQPAARFLSLDVFRGLTVFLMIVVNTAGPQLVHAPWFGFTAADAVPSFLFAVGCSMAFAFSKPIPLN---DFTVKVLRRA--ALIFLLGFLMYWFPFVRKVDGDWALIPFSDTRVMGVLQRIALCYLLAAFAVRWLSPRLIVALCAVLLLGYWAILMAFGDPAAPLSKLGNAGTRLLIGQNHLYRKDGGFDPEGLLGTLPSTVNVLAGYLAARFLKENPGSSQAMGRMAIAGLVLILAGLVW--------------SPLFPIAKKLWTSSFVLLTVGIDLILLAGLAK-----NPGTYFFQVFGLNPLVLYLFSELFVWVGVNLFQAVMPGAFGSLLCALAYTLVCWLLGYVMARRG........... 367
9 -18.100[I] COG1835 Predicted acyltransferases  ali follow..  13  7..........................IDGLRAVAVLPVVLFHFGVSAIP-------GFT-GVDIFFVISGYLISGSLLDDLERGQFSIGR--YWRRARRILPALTFVILLASIAAWFILLPSDLHEYSLSVIAASTFWSNIYFWKTTNYFSIDAELRPLLHTWSLYYIFAPVLVYLIYRYASKRWLTILLPIAIGSFALAVMATTLAPTAGFY---IWELA--LGAMLMLRKPPALASRPLTELIGLAGFGLIAFGFVTISESDPFP-----------------GYNALFPCIGTALLIYA-RPVPVATQVLRLTPLVWIGLISYSLYLVHWPINSFVHYLSLKAIGVPTILAMIVASVALATFSWKYVEQPFRQKRAFTAPLPI 350
10 -17.700[S] COG2311 Predicted membrane protein  ali follow..  11  2.....................ERNVTLDFVRGVAILGILLLNISAFGLPKAAYLNPAWYGAITPFALLFGAGLQMLLPR---------GRRWIQSRLTLLVLLGFIHGLLF----------------------------------------------DILLAYGLVGLI---CWRLVRDAPSVKSLFNTGVMLYLVGLGVILYEKYWKLHGGVEAISNRAMMLIGAALMRSGWLKGQFSLRHYRRTGFVLVAIGVTINLPAIALQWQLDWAYRWCAFLLQMPRE-------FQAIGYASLFYGFWPQLSRFKLVLAIACVGRMALTNYLLQTLICTTLFYHLGLFMHFDRLELLAFVIPVWLANIL................... 350
11 -13.900[R] KOG3700 Predicted acyltransferase  ali follow..  12  249...HGILALSKCQGDIQNEAEGQVTSLNCIRTISTVWVILGHFTKTYMGALLVNAY----AVDTFFFISAFLLSFLWFKQLQKQRKALISMFYVHRIARLSPAYYIAILFVTFVYIRMLRDMPAFMSPAIQD---------------LNLLYIENIVDTKNIYLALYLMSPILLLSFAIGGAVFGLFASVVALVASTAFNAYQIFFWYVWNYYNPLIRCQIYIMGLVLGYFMRKVPKININPWVDRIMWVLSLGSMVFVVLVIQDYSSGDGWTPVQTAL---YRSYSKTALAKLILESVSEQVF---IRDFMSLSFWTPLARLSFCAYLVHWMVLGYFFGRNHSELYFSTLSYFFLIPVTALSFVIAIFWSSMFEIP........ 724
12 -11.200[R] KOG1699 O-acetyltransferase  ali follow..  13  151MTSLRKHNDKSPISGKSILYLNRH-QTEEWKGWMQVLFLMYHYFAAAEIYNAIRIF-----IAAYVWMTGFGNFSYYYVRKD---------SVARFAQMMWRLNFFVAFCCIVLNNDYMLYYICP-------------HTLFTLMVYGALGIFSKYNEIGSVMALKIFSCFLVVFLLWEIPGAFEIFWGPLTFLLGYNDPAKPDLHRLHEWHFRSGLDRYIWIIGMIYAYTVERWMEKLEDCETKKRLSIKAAIVTITVLVGYVWYECIYKLDRTSYNMYHPYTSWIPITSVHKTLF----------------LLVFIFVSYVT............................................................. 435
13 -10.800[S] COG5062 Uncharacterized membrane protein  ali follow..  10  99..VLRRKPGCCLTKKNENTFDRRIAGVTFYRSQMMLVTVTCILAVDFYAKVETWGTSLMDGVGSFMFSSGTV-----AGRKNDIKKPNAFKNVLWNSFILLILGFARMFLTKSI-----------------NYQEHVSEYGMHWNFFFTLGFMALGVFFFRRSLKKVSYFNLATFITLLHHCLLVLTPFQKWALSA----RTNILAQNREGIASLPGYIAIYFYGMYTGSVVLADRPLMYTRAESWKRFQRLLFPLCILLVLYL------VSNFLSVGVSRRLANTPYVANVAFIILIDAYLFPSSVPYGSRVPKLLEDANNNGLLVFLIANVLTGVVNLSFDTLHSSNAKGLTIMTMYLFIICYMAHWLAQHG........... 454
14 -10.300[S] KOG0411 Uncharacterized membrane protein  ali follow..  10  85WPGNPSSYPKQSVDAPQDDEPYTSMAIDRTRFLIIGCVVIAIFASDFLGKSMGYGLKLMDGVGSFVYNAGFFSTRADPQRKMKNALSSFFFGML-RYLSKFGVHLNFFLMLGVLNLASL----------------VINTRANFLLGFG----------MCLTHELFLKFFGLEKLIYSSARSSIITSN--------------------IEGITFLLPQMGMFLMAADISKVVFKKKNLSIIILYNAFFVAVLSIARVYS-------------------SCRRIHNLYFCMVIMLLTTHGIVFEVFSRTFKIRNLEMHRFISKYLLFILVWSNMLVTLNKLLSASKDMSRCSSHALCITYLVLVFYVPCAINSKV........... 414
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 2 6 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.