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Query: [G] COG4677 Pectin methylesterase, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKKLast
1 -130.000[G] COG4677 Pectin methylesterase  ali  100  1MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK 427
2 -13.300[P] COG3420 Nitrous oxidase accessory protein  ali follow..  12  32...........................................................................................AVGESVQAAIEKAEPGD-----VVRLRAGRHEGAVVIDRA---IELTGEPGAVLD-----------------------------------------------GLGTGNAITVNAPNAIVRGLEVHGS--GDNLPDLHSGIFVSRTATGARVENNRLIGNTYGIYLHGAADSIAIGNEVLGRRGVRMAETGSGV-SVWNAPGAQVVGNTIRYGRDGNASRKNIFRDNVMEDVRFAVHYMYTD............................................................................................... 217
3 -6.030[Z] KOG3121 Dynactin, subunit p25  ali follow..  13  10....................................................................................................................................................................................................................................KDEYVETASGNKVSRHTVLCGSQNIILNGKV-------------IVQSGAIIRGDLANVTGRYCVIGKNSVIRPKQFSKGIAFFPMHVGEHVFVGEGAVVSAATI----GSYVYIGK---------NAIIGRRCVLKDCCVIEDG...................................................... 131
4 -6.020[M] COG5434 Endopolygalacturonase  ali follow..  10  66....................................................................................GNPSNSQPDASRIQTAIDNCPAGQAVRLVKGSAGESGFKSGVTL-RDTVGSGIVGDGIGRGGSLVTSGPNANRLTWWDIAYLNKTKGLNQQNPRLVQLYNGSAFTLYRVTVQNSPNFHIVTAGVTAWGIKIVTTCFTPETVKNTDGFDPG-QSTNVVLANSYISTGDDHVAIKASGGATR-------NLLFAHNHFYYGHGLSIGSSNMQVTDLAMDGNDSSGGNGLRIKSDISRGGKVNNIVYNGICMRNVKE......................................................................................... 393
5 -5.950[QC] COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein  ali follow..  20  10..................................................................................................................................................................................................VTGQIVCTVRHQGLAHDKLLMVEMIDAQGNPDGQCAVAIDSIG----------AGTGEWVLLVSGSSARQAHRSELS-----DLCVIGIVDEVVAGGKVVFHK.................................................................................................................................. 99
6 -5.740[R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily  ali follow..  11  2...............................................................................................................................................................................................SYYAFEGLIPVVHPDAFVHPSAVLIGDVIVGAGVYIGPLASLR--GDYGRLILEAGSNLQDGCIMHGYCDTDTIVHENGHGAILHGCVVGRDA--LVGMNSVIMDGAVI-------GEESIVAAMS--------FVKAGFQG---EARQLLVGSP................................................................................. 137
7 -5.660[J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit  ali follow..  11  2..........................................................................................REQLEALRDDAIKKIEQAQEKKVVQEIRVKYLGKKGPVTEVLRGMGKLSPEERPVIGQLANDVREAIGKAIESKMEALEQAEIHRKLQEETIDVTLPGRPVLKGGAHPLTATITEVEDLFIGLGFSVAEGPQIETDYYNFEALNLPKDHPA------RDMQDSFYFTDELLLRTQTSPVQARTMEKKIICPGKVDDDDATHSHQFMQIE-----------GLYVDHGVRMSDLKGVLQAFAKSFFGEERSIRLRPSFFPFTEPSVEVDVSCGICHGRVCKQTGWIEILGAG.............................................. 288
8 -5.180[KT] COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases)  ali follow..  12  25..............................................................................SPSIRQMMQAMNLKSPAPIQSRLEHLRTKG-----YIEWTEGKARTIRVLQPIKQGVPVLGAIAAGGLIEPFTDAVEHIDFSNF------------------------------VLPAQTYALRVTGDSMIEDDLVFLRPVPEPDQLKNGTIVAARVDGYGNTLKRFYRSGDRITLKPANPK--------------YNPIEVAAIQVEVQGSLVGVWRG.................................................................................................................................. 199
9 -4.960[S] COG2717 Predicted membrane protein  ali follow..  14  46........................................................................................................................................................................................................................DPVKTFEHLLGLWALRFLI-----------------TLLVTPMRDLTGITLLRYRRAL-------GLLAFYY----ALMHFTTYMVLDQGLNLSAIITDIVRRPFITIGMLLVPLALTSNNWSIRKLGRRWSSLHKLVYIAIAG................................................................... 166
10 -4.930[M] COG0729 Outer membrane protein  ali follow..  11  48......................................................................PDTESVKLKPKFPVRIDTQDSEIKDMVEEHLPLITQQQEEVLDKEQTGFGYFSSKVSLTEKDGAYTVITPGPRTKIANVGVAILGDILSDGNLAEYYRNALENWQQPVGSDFDQDSWENSKT-----SVLGAVTRKAYPLAKLGNTRAAVNPDTATADLNVVVD-SGRPIAFGDFEITGTQR----------------------YPEQIVSGLARFQPGT---PYDLDLLLDFQQALEQNGHASVQADFDRLQGDRVPVKVSVTEVKRHKLETGIRLDSEYGLGGKIAYDYYNL............................................................... 330

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Robinson-Rechavi M, Godzik A. Structural Genomics of Thermotoga maritima Proteins Shows that Contact Order Is a Major Determinant of Protein Thermostability. Structure (Camb). 2005 Jun;13(6):857-60.